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Professor Justin Roake

Justin RoakeProfessor of Surgery

MB ChB(Otago) DPhil(Oxf) FRCS FRACS(Vascular, Endovascular, and Transplant Surgery)

Email justin.roake@cdhb.health.nz

Justin Roake is a specialist in vascular surgery and transplantation surgery.

He is Clinical Director of the Department of Vascular Endovascular and Transplant Surgery at Christchurch Hospital. He has a DPhil in transplantation immunology focused upon the biology of dendritic cells.

Professor Roake is co-convenor of the Trainee Intern year student attachment to surgery. He is Specialty Editor (Transplantation) of ANZ Journal of Surgery.

Research interests

  • The biology of vascular disease
  • Clinical prioritisation for surgery
  • Medical education
  • Modelling of clinical assessments of risks and benefits in surgery

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Publications

Prebble, H., Cross, S., Marks, E., Healy, J. L., Searle, E., Aamir, R., Butler, A., Roake, J., Hock, B., Anderson, N., & Gieseg, S. P. (2018). Induced macrophage activation in live excised atherosclerotic plaque. Immunobiology. Advance online publication. doi: 10.1016/j.imbio.2018.03.002

Khashram, M., Kvizhinadze, G., Khashram, Z., Williman, J. A., Jones, G. T., & Roake, J. A. (2018). Development and validation of a predictive model to aid in the management of intact abdominal aortic aneurysms. European Journal of Vascular & Endovascular Surgery, 56(1), 48-56. doi: 10.1016/j.ejvs.2018.03.013

Roake, J., & Morton, J. (2018). Live kidney donation: Managing the "tyranny of the gift". New Zealand Medical Journal, 131(1474), 7-9. Retrieved from https://www.nzma.org.nz/journal

Khashram, M., Pitama, S., Williman, J. A., Jones, G. T., & Roake, J. A. (2017). Survival disparity following abdominal aortic aneurysm repair highlights Inequality in ethnic and socio-economic status. European Journal of Vascular & Endovascular Surgery, 54(6), 689-696. doi: 10.1016/j.ejvs.2017.08.018

Khashram, M., Williman, J. A., Hider, P. N., Jones, G. T., & Roake, J. A. (2017). Management of modifiable vascular risk factors improves late survival following abdominal aortic aneurysm repair? A systematic review and meta-analysis. Annals of Vascular Surgery, 39, 301-311. doi: 10.1016/j.avsg.2016.07.066

Chapter in Book - Research

Roake, J. A. (2003). Managing waiting lists. In R. D. C. Gauld (Ed.), Continuity amid chaos: Health care management and delivery in New Zealand. (pp. 103-121). Dunedin: Otago University Press.

Roake, J. A. (2000). The adrenal gland. In P. J. Morris & W. Wood (Eds.), The Oxford Textbook of Surgery (2nd Edition) Vol 2. (pp. 1143-1165). Oxford: Oxford University Press.

Austyn, J. M., Chao, D., Lin, C.-L., Roake, J. A., & Suri, R. M. (2000). Dendritic cells. In M. J. Dallman & J. R. Lamb (Eds.), Haematopoietic and Lymphoid Cell Culture. (pp. 23-49). Cambridge University Press.

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Journal - Research Article

Prebble, H., Cross, S., Marks, E., Healy, J. L., Searle, E., Aamir, R., Butler, A., Roake, J., Hock, B., Anderson, N., & Gieseg, S. P. (2018). Induced macrophage activation in live excised atherosclerotic plaque. Immunobiology. Advance online publication. doi: 10.1016/j.imbio.2018.03.002

Khashram, M., Kvizhinadze, G., Khashram, Z., Williman, J. A., Jones, G. T., & Roake, J. A. (2018). Development and validation of a predictive model to aid in the management of intact abdominal aortic aneurysms. European Journal of Vascular & Endovascular Surgery, 56(1), 48-56. doi: 10.1016/j.ejvs.2018.03.013

Khashram, M., Pitama, S., Williman, J. A., Jones, G. T., & Roake, J. A. (2017). Survival disparity following abdominal aortic aneurysm repair highlights Inequality in ethnic and socio-economic status. European Journal of Vascular & Endovascular Surgery, 54(6), 689-696. doi: 10.1016/j.ejvs.2017.08.018

Khashram, M., Williman, J. A., Hider, P. N., Jones, G. T., & Roake, J. A. (2017). Management of modifiable vascular risk factors improves late survival following abdominal aortic aneurysm repair? A systematic review and meta-analysis. Annals of Vascular Surgery, 39, 301-311. doi: 10.1016/j.avsg.2016.07.066

Khashram, M., Thomson, I. A., Jones, G. T., & Roake, J. A. (2017). Abdominal aortic aneurysm repair in New Zealand: A validation of the Australasian Vascular Audit. ANZ Journal of Surgery, 87(5), 394-398. doi: 10.1111/ans.13702

Jones, G. T., Tromp, G., Kuivaniemi, H., Gretarsdottir, S., Baas, A. F., Giusti, B., … Phillips, L. V., Williams, M. J. A., Wei, W., … Thomson, I. A., Krysa, J., Hill, G. B., Roake, J., Merriman, T. R., … van Rij, A., … Bown, M. J. (2017). Meta-analysis of genome-wide association studies for abdominal aortic aneurysm identifies four new disease-specific risk loci. Circulation Research, 120, 341-353. doi: 10.1161/circresaha.116.308765

Khashram, M., Tiong, L. C., Jones, G. T., & Roake, J. A. (2017). The impact of CT colonography on abdominal aortic aneurysm referrals in a tertiary hospital. Journal of Medical Imaging & Radiation Oncology, 61(2), 180-184. doi: 10.1111/1754-9485.12535

Khashram, M., Hider, P. N., Williman, J. A., Jones, G. T., & Roake, J. A. (2016). Does the diameter of abdominal aortic aneurysm influence late survival following abdominal aortic aneurysm repair? A systematic review and meta-analysis. Vascular, 24(6), 658-667. doi: 10.1177/1708538116650580

Khashram, M., Williman, J. A., Hider, P. N., Jones, G. T., & Roake, J. A. (2016). Systematic review and meta-analysis of factors influencing survival following abdominal aortic aneurysm repair. European Journal of Vascular & Endovascular Surgery, 51(2), 203-215. doi: 10.1016/j.ejvs.2015.09.007

Khashram, M., Falconer, R., Mahmud, A., Khanafer, A., Laws, P., Beresford, T., & Roake, J. (2016). Rapid access carotid endarterectomy: Winning the RACE following a natural disaster. New Zealand Medical Journal, 129(1443), 53-60. Retrieved from http://www.nzma.org.nz/journal

Khashram, M., He, Q., Oh, T. H., Khanafer, A., Wright, I. A., Vasudevan, T. M., … Roake, J. A., & Civil, I. (2016). Late radiological and clinical outcomes of traumatic thoracic aortic injury managed with thoracic endovascular aortic repair. World Journal of Surgery, 40, 1763-1770. doi: 10.1007/s00268-016-3457-6

INSITE Collaborators (INternational Study group for Identification and Treatment of Endofibrosis), including Roake, J. (2016). Diagnosis and management of iliac artery endofibrosis: Results of a Delphi consensus study. European Journal of Vascular & Endovascular Surgery, 52(1), 90-98. doi: 10.1016/j.ejvs.2016.04.004

Peek, K. N., Khashram, M., Wells, J. E., & Roake, J. A. (2016). The costs of elective and emergency abdominal aortic aneurysm repair: A comparative single centre study. New Zealand Medical Journal, 129(1433), 55-65. Retrieved from http://www.nzma.org.nz/journal

Griffin, J. L., Clarke, G. A., Roake, J. A., & Lewis, D. R. (2015). A nurse-run clinic for patients with incidentally discovered small abdominal aortic aneurysms is feasible and cost-effective. Vascular, 23(2), 138-143. doi: 10.1177/1708538114537049

Khashram, M., Jones, G. T., & Roake, J. A. (2015). Prevalence of abdominal aortic aneurysm (AAA) in a population undergoing computed tomography colonography in Canterbury, New Zealand. European Journal of Vascular & Endovascular Surgery, 50(2), 199-205. doi: 10.1016/j.ejvs.2015.04.023

Janmale, T., Genet, R., Crone, E., Flavall, E., Firth, C., Pirker, J., Roake, J. A., & Gieseg, S. P. (2015). Neopterin and 7,8-dihydroneopterin are generated within atherosclerotic plaques. Pteridines, 26(3), 93-103. doi: 10.1515/pterid-2015-0004

Maze, M. J., Laws, P., Buckenham, T., Pithie, A., Gallagher, K., Metcalf, S., Roake, J., & Chambers, S. T. (2013). Outcomes of infected abdominal aortic grafts managed with antimicrobial therapy and graft retention in an unselected cohort. European Journal of Vascular & Endovascular Surgery, 45(4), 373-380. doi: 10.1016/j.ejvs.2013.01.019

Graham, P., Martin, G., Fraser, J., Cumming, J., Williams, H., Davidson, A., … Roake, J., & van Rij, A. (2012). Equity of access and variation in general surgeons' clinical judgements of patient priority. International Journal of Person Centered Medicine, 2(4), 883-898. doi: 10.5750/ijpcm.v2i4.298

Zainon, R., Ronaldson, J. P., Janmale, T., Scott, N. J., Buckenham, T. M., Butler, A. P. H., … Gieseg, S. P., Roake, J. A., & Anderson, N. G. (2012). Spectral CT of carotid atherosclerotic plaque: Comparison with histology. European Radiology, 22(12), 2581-2588. doi: 10.1007/s00330-012-2538-7

Kieser, D. C., Roake, J. A., Hammond, C., & Lewis, D. R. (2011). Negative pressure wound therapy as an adjunct to compression for healing chronic venous ulcers. Journal of Wound Care, 20(1), 35-37.

MacKenzie, K. A., Miller, A. P., Hock, B. D., Gardner, J., Simcock, J. W., Roake, J. A., Dachs, G. U., Robinson, B. A., & Currie, M. J. (2011). Angiogenesis and host immune response contribute to the aggressive character of non-melanoma skin cancers in renal transplant recipients. Histopathology, 58(6), 875-885. doi: 10.1111/j.1365-2559.2011.03845.x

Khashram, M., Roake, J. A., & Lewis, D. R. (2010). Patient flow to carotid endarterectomy: Hastening the patient journey. ANZ Journal of Surgery, 80(6), 406-410. doi: 10.1111/j.1445-2197.2010.05308.x

Ching, T., Roake, J. A., & Lewis, D. R. (2010). Net-based information on varicose vein treatments: A tangled web. New Zealand Medical Journal, 123(1323). Retrieved from http://journal.nzma.org.nz/journal/123-1323/4355/content.pdf

Mackenzie, K. A., Wells, J. E., Lynn, K. L., Simcock, J. W., Robinson, B. A., Roake, J. A., & Currie, M. J. (2010). First and subsequent nonmelanoma skin cancers: Incidence and predictors in a population of New Zealand renal transplant recipients. Nephrology Dialysis Transplantation, 25, 300-306. doi: 10.1093/ndt/gfp482

Edirimanne, S., Roake, J. A., & Lewis, D. R. (2010). Delays in discharge of vascular surgical patients: A prospective audit. ANZ Journal of Surgery, 80(6), 443-446. doi: 10.1111/j.1445-2197.2009.05130.x

Moesbergen, T., Law, A., Roake, J., & Lewis, D. R. (2009). Diastasis recti and abdominal aortic aneurysm. Vascular, 17(6), 325-329. doi: 10.2310/6670.2009.00047

Buckenham, T., McKewen, M., Laing, A., Roake, J., Lewis, D., & Gordon, M. K. (2009). Cyanoacrylate embolization of endoleaks after abdominal aortic aneurysm repair. ANZ Journal of Surgery, 79(11), 841-843. doi: 10.1111/j.1445-2197.2009.05113.x

Suh, J., Roake, J. A., & Lewis, D. R. (2009). Quality of clinical notes for vascular surgery admissions: A CRABEL score review. ANZ Journal of Surgery, 79(7-8), 539-543. doi: 10.1111/j.1445-2197.2009.04986.x

Laney, J., Roake, J., & Lewis, D. R. (2009). Topical negative pressure wound therapy (TNPWT): Current practice in New Zealand. New Zealand Medical Journal, 122(1295). Retrieved from http://www.nzma.org.nz/journal

Khashram, M., Roake, J. A., & Lewis, D. R. (2009). The effect of vacuum-assisted closure on the tissue oxygenation of venous ulcers: A pilot study. Wounds, 21(9), 249-253.

Khashram, M., Huggan, P., Ikram, R., Chambers, S., Roake, J. A., & Lewis, D. R. (2009). Effect of TNP on the microbiology of venous leg ulcers: A pilot study. Journal of Wound Care, 18(4), 164-167.

Firth, C. A., Crone, E. M., Flavall, E. A., Roake, J. A., & Gieseg, S. P. (2008). Macrophage mediated protein hydroperoxide formation and lipid oxidatiojn in low density lipoprotein are inhibited by the inflammation marker 7,8-dihydroneopterin. Biochimica et Biophysica Acta: Molecular Cell Reserch, 1783(6), 1095-1101. doi: 10.1016/j.bbamcr.2008.02.010

Carter, K., Roake, J. A., Buckenham, T., Frampton, C. M., & Lewis, D. R. (2008). Informed consent for vascular intervention: Completing one audit loop. New Zealand Medical Journal, 121(1269). Retrieved from http://journal.nzma.org.nz/journal/121-1269/2928/content.pdf

Horrocks, E., Roake, J., & Lewis, D. (2008). Best practice for assessment of patients with varicose veins. New Zealand Medical Journal, 121(1274). Retrieved from http://journal.nzma.org.nz/journal/121-1274/3065/content.pdf

Oram, B. J., Buckenham, T. M., Roake, J. A., & Lewis, D. R. (2008). Treatment delays for patients exiting an aortic aneurysm surveillance programme. ANZ Journal of Surgery, 78, 148-150.

Buckenham, T., Roake, J., Lewis, D., Gordon, M., & Wright, I. (2007). Abdominal aortic aneurysm surveillance: Application of the UK Small Aneurysm Trial to a New Zealand tertiary hospital. New Zealand Medical Journal, 120(1251). Retrieved from http://journal.nzma.org.nz/journal/120-1251/2472/content.pdf

Kang, A., Buckenham, T., Roake, J., & Lewis, D. (2007). Computed tomography arteriography to assess greater saphenous vein as a conduit for peripheral bypass. ANZ Journal of Surgery, 77, 870-872.

Nakka, P., Chu, J. J., Roake, J., & Lewis, D. (2007). Variability in counselling patients regarding the hereditary nature of abdominal aortic aneurysm (AAA): Lack of evidence or resources? New Zealand Medical Journal, 120(1251). Retrieved from http://journal.nzma.org.nz/journal/120-1251/2460/content.pdf

Moot, A. R., Ledingham, K. M., Wilson, P. F., Senthilmohan, S. T., Lewis, D. R., Roake, J., & Allardyce, R. (2007). Composition of volatile organic compounds in diathermy plume as detected by selected ion flow tube mass spectrometry. ANZ Journal of Surgery, 77, 20-23.

Muthu, C., Chu, J. J., Le Heron, C., Roake, J. A., & Lewis, D. R. (2007). Patient awareness of risk factors for perpheral vascular disease. Annals of Vascular Surgery, 21(4), 433-437.

Kandula, T., Roake, J. A., & Lewis, D. R. (2007). Vacuum assisted closure devices in the elderly: A word of caution. New Zealand Medical Journal, 120(1263). Retrieved from http://journal.nzma.org.nz/journal/120-1263/2752/content.pdf

Kuiper, N., Gordon, M., Roake, J., & Lewis, D. (2006). Treating claudication in 5 words (stop smoking and keep walking) is no longer enough: An audit of risk factor management in patients prescribed exercise therapy in New Zealand. New Zealand Medical Journal, 119(1231). Retrieved from http://journal.nzma.org.nz/journal/119-1231/1918/content.pdf

Mandhan, P., Beasley, S., Hale, T., Ellmers, L., Roake, J., & Sullivan, M. (2006). Sonic hedgehog expression in the development of hindgut in ETU-exposed fetal rats. Pediatric Surgery International, 22, 31-36.

Su, H., Gordon, M., Roake, J., & Lewis, D. (2006). Management of risk factors: A survey of New Zealand vascular surgeons. New Zealand Medical Journal, 119(1231). Retrieved from http://journal.nzma.org.nz/journal/119-1231/1905/content.pdf

Doughty, C., MacCormick, A., Roake, J., Fraser, J., Hider, P., Kirk, R., … van Rij, A., & Theis, J.-C. (2005). Prioritisation of elective surgery in New Zealand: The reliability study. New Zealand Medical Journal, 118(1219). Retrieved from http://journal.nzma.org.nz/journal/118-1219/1590/content.pdf

Temple-Doig, L., Gordon, M., Buckenham, T., Roake, J., & Lewis, D. (2005). Informed consent for vascular intervention. New Zealand Medical Journal, 118(1221). Retrieved from http://journal.nzma.org.nz/journal/118-1221/1630/content.pdf

Hock, B. D., Roberts, G., McKenzie, J. L., Gokhale, P., Salm, N., McLellan, A. D., Patton, N. W., & Roake, J. A. (2005). Exposure to the electrofusion process can increase the immunogenicity of human cells. Cancer Immunology, Immunotherapy, 54, 880-890.

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