Eukaryote genomes and genome evolution; phylogenetics; cytogenetics and chromosomes; extensions of Mendelian genetics; genetic mapping in eukaryotes; genes in populations; quantitative genetics.
GENE 222 gives a broad coverage of all of the concepts that are central to modern eukaryote genetics including human genetics. As such it is directly relevant for students with an interest in any of the biological or biomedical sciences. The different parts of the paper are linked by a common theme of genetic analysis and the use of specific examples to illustrate general principles. The lecture course is complemented by a laboratory course that gives hands-on experience of many of the methods that are used in genetic analysis of eukaryotes.
|Paper title||Genes, Chromosomes and Populations|
|Teaching period||Second Semester|
|Domestic Tuition Fees (NZD)||$1,080.30|
|International Tuition Fees (NZD)||$5,159.70|
- CELS 191 and 90 further points
- Recommended Preparation
- GENE 221 and BIOC 221
- Schedule C
- Appropriate for students majoring in genetics, other biological and health sciences and molecular biotechnology.
- More information link
- Teaching staff
Convenor: Professor Iain Lamont (Department of Biochemistry)
Other teaching staff: Professor Jon Waters (Department of Zoology), Dr Janice Lord (Department of Botany), Professor Tony Merriman (Department of Biochemistry), Dr Martyn Kennedy (Department of Pathology) and Dr Gillian MacKay (Genetics Programme)
- Paper Structure
- The lecture course is divided into seven blocks:
- Eukaryote genomes and genome evolution
- Cytogenetics and chromosomes
- Extensions of Mendelian genetics
- Genetic mapping in eukaryotes
- Genes in populations
- Quantitative genetics
- Teaching Arrangements
There are six weeks of laboratory classes, in three 2-week blocks, and students are assigned to one of four lab streams.
The recommended text book for GENE 221 is: Introduction to Genetic Analysis (Griffiths, Wessler, Carroll, Doebley), 11th Edition. Earlier editions of this book are also satisfactory if you have access to a copy.
- Graduate Attributes Emphasised
- Global perspective, Interdisciplinary perspective, Scholarship, Critical thinking,
View more information about Otago's graduate attributes.
- Learning Outcomes
- The broad objectives of GENE 222 are to understand:
- Genomic variation within and between species
- How to construct and interpret phylogenetic trees
- The origins and diagnostic features of karyotypic variation
- The extensions of Mendelian genetics
- How to test alternative genetic hypotheses
- How to map monogenic and complex disease genes
- How evolution is explained by principles of variation, heredity and selection
- Quantitative traits and the norm of reaction
- Heritability, QTLs and their uses