Overview
Molecular machines and protein complexes. How the atomic structures of proteins dictate function, reflect diversity and guide bioengineering. Design of novel proteins and drugs. Proteome and protein structure analysis.
The diverse enzymatic activities and interactions of proteins underpin all life on our planet. The atomic resolution structures of proteins provide profound insights into protein function, its evolution and how it can be manipulated in medicine and biotechnology. BIOC 351 focuses on these aspects of protein biochemistry and uses selected examples from research articles to illustrate how deep, fundamental understanding is achieved. With a strong emphasis on the experimental basis of biochemistry, BIOC 351 will prepare students for employment in jobs based on laboratory science or on the knowledge it generates. In addition, the paper emphasises skills that are crucial for success during postgraduate study in many life sciences.
About this paper
| Paper title | Advanced Protein Biochemistry |
|---|---|
| Subject | Biochemistry |
| EFTS | 0.15 |
| Points | 18 points |
| Teaching period | Semester 1 (On campus) |
| Domestic Tuition Fees ( NZD ) | $1,243.65 |
| International Tuition Fees | Tuition Fees for international students are elsewhere on this website. |
- Prerequisite
- BIOC 221 and BIOC 222
- Schedule C
- Science
- Notes
- In approved cases another 200-level science paper may be substituted for BIOC 221.
- Eligibility
This paper is suitable for students in any discipline who have an interest in protein structure and function.
- Contact
- biochem300.tf@otago.ac.nz
- Teaching staff
Convenor: Associate Professor Craig Marshall and Dr Ben Peters
- Paper Structure
Lectures are held twice a week for the semester with a third lecture per week for half of the semester.
Labs are held once a week per stream for five weeks.
- Teaching Arrangements
Arrangements can be made for students to leave the lab for other commitments such as lectures and are able to plan their laboratory experiments to fit in with those commitments.
- Textbooks
- Voet, D., Voet, J. G., and Pratt, C. W. Fundamentals of Biochemistry, John Wiley & Sons.
- Graduate Attributes Emphasised
- Lifelong learning, Scholarship, Critical thinking, Research, Self-motivation.
View more information about Otago's graduate attributes. - Learning Outcomes
Students who successfully complete this paper will:
- Articulate a detailed understanding of protein structure, molecular interactions and how these features define the functions of enzymes and signaling molecules
- Identify and critically evaluate relevant information about protein structure, function and engineering in primary sources and authoritative databases
- Critically assess experimental data from X-ray crystallography, mass spectrometry, and other biophysical techniques
- Understand the relationship between hypothesis, experimental design and data and know how to apply this to attain knowledge
- Design and execute experiments using contemporary biochemical techniques
- Assessment details
30% Internal assessments
70% Final examination