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Overview

Gene and genome structure and function. DNA replication. Genetic code and protein synthesis. Concepts of DNA cloning and gene analysis in disease and forensics. Concepts of gene therapy. Concepts of energy metabolism involving carbohydrates, fats and proteins. Regulation and integration of metabolism. Cell signalling in health and disease. Role of clinical diagnostics. Metabolic processes in drug metabolism and body organ function.

The replication of the genome of an organism in cell division and the expression of genes during the life of a cell are central to the functioning of the organism. Molecular-level understanding of the gene complement of the genome is critical for understanding health and disease processes. Understanding concepts of nucleic acid polymer and gene analysis are important in molecular diagnosis. Gene expression produces proteins, many of which catalyse reactions in metabolic pathways involved with the inter-conversion of carbohydrates, proteins and lipids that are essential for energy production and cell function. All of these cellular activities require co-ordination and control mediated by cell signaling processes. MELS 230 is complementary to and extends the biochemistry covered in the first-year paper BIOC 192, providing a foundation of biochemistry for students in the MELS programme.

About this paper

Paper title Biochemistry (for BMLSc)
Subject Medical Laboratory Science
EFTS 0.1425
Points 18 points
Teaching period Semester 1 (On campus)
Domestic Tuition Fees ( NZD ) $1,447.66
International Tuition Fees Tuition Fees for international students are elsewhere on this website.
Restriction
BIOC 221, BIOC 230 and PHCY 231. May not be taken if BIOC 223 has been passed prior to 2019 or HUNT 221 has been passed from 2019 onwards
Limited to
BMLSc
Eligibility
This paper provides a foundation of biochemistry, combined with BIOC 192, that is suitable for MELS students who do not advance biochemistry further in the MELS programme. MELS 230 is a terminating paper; it is not possible to pursue advanced biochemistry papers from this paper.
Contact

biochemistry@otago.ac.nz

Teaching staff

Dr Nicole Power

Textbooks

A variety of textbooks are suitable for MELS230. We recommend: Voet, D., Voet, J. G., and Pratt, C. W. Fundamentals of Biochemistry, John Wiley & Sons.

Graduate Attributes Emphasised
Global perspective, Interdisciplinary perspective, Lifelong learning, Scholarship, Communication, Critical thinking, Cultural understanding, Ethics, Environmental literacy, Information literacy, Research, Self-motivation, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes

Students who successfully complete this paper will:

  • Articulate a broad understanding of contemporary biochemistry, molecular life sciences and related scientific fields
  • Appropriately communicate biochemical concepts to both specialist and general audiences
  • Identify and critically evaluate relevant information
  • Work effectively both independently and as part of a team
Assessment details

Internal assessment – 20% total.

Final Exam – 80% (with a minimum requirement of 50% in the final exam)

Overview

Gene and genome structure and function. DNA replication. Genetic code and protein synthesis. Concepts of DNA cloning and gene analysis in disease and forensics. Concepts of gene therapy. Concepts of energy metabolism involving carbohydrates, fats and proteins. Regulation and integration of metabolism. Cell signalling in health and disease. Role of clinical diagnostics. Metabolic processes in drug metabolism and body organ function.

The replication of the genome of an organism in cell division and the expression of genes during the life of a cell are central to the functioning of the organism. Molecular-level understanding of the gene complement of the genome is critical for understanding health and disease processes. Understanding concepts of nucleic acid polymer and gene analysis are important in molecular diagnosis. Gene expression produces proteins, many of which catalyse reactions in metabolic pathways involved with the inter-conversion of carbohydrates, proteins and lipids that are essential for energy production and cell function. All of these cellular activities require co-ordination and control mediated by cell signaling processes. MELS 230 is complementary to, and extends the biochemistry covered in the first-year paper BIOC 192, providing a foundation of biochemistry for students in the MELS programme.

About this paper

Paper title Biochemistry (for BMLSc)
Subject Medical Laboratory Science
EFTS 0.1425
Points 18 points
Teaching period Semester 1 (On campus)
Domestic Tuition Fees Tuition Fees for 2027 have not yet been set
International Tuition Fees Tuition Fees for international students are elsewhere on this website.
Restriction
BIOC 221, BIOC 230 and PHCY 231. May not be taken if BIOC 223 has been passed prior to 2019 or HUNT 221 has been passed from 2019 onwards
Limited to
BMLSc
Eligibility
This paper provides a foundation of biochemistry, combined with BIOC 192, that is suitable for MELS students who do not advance biochemistry further in the MELS programme. MELS 230 is a terminating paper; it is not possible to pursue advanced biochemistry papers from this paper.
Contact

biochemistry@otago.ac.nz

Teaching staff

Dr Nicole Power

Textbooks

A variety of textbooks are suitable for MELS230. We recommend: Voet, D., Voet, J. G., and Pratt, C. W. Fundamentals of Biochemistry, John Wiley & Sons.

Graduate Attributes Emphasised
Global perspective, Interdisciplinary perspective, Lifelong learning, Scholarship, Communication, Critical thinking, Cultural understanding, Ethics, Environmental literacy, Information literacy, Research, Self-motivation, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes

Students who successfully complete this paper will:

  • Articulate a broad understanding of contemporary biochemistry, molecular life sciences and related scientific fields
  • Appropriately communicate biochemical concepts to both specialist and general audiences
  • Identify and critically evaluate relevant information
  • Work effectively both independently and as part of a team
Assessment details

Internal Assessment - 20% total.

Final Exam - 80% (with a minimum requirement of 50% in the final exam).

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