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    Exploration of how experimental neuromodulation can be used to support or refute current concepts of pathophysiology in clinical human neuroscience.

    About this paper

    Paper title Applied Human Neuroscience
    Subject Neuroscience
    EFTS 0.1667
    Points 20 points
    Teaching period Semester 1 (On campus)
    Domestic Tuition Fees ( NZD ) $1,797.86
    International Tuition Fees Tuition Fees for international students are elsewhere on this website.
    May not be credited together with NEUR463 passed in 2016 or 2017 or with NEUR472 passed in 2018.
    This paper is available to 400-level Neuroscience majors.Enrolments for this paper require departmental permission. View more information about departmental permission.

    Neurosurgery Administrator (

    Teaching staff

    Professor Dirk de Ridder

    Paper Structure

    NEUR 453 Applied Human Neuroscience will consist of 12 two-hour seminars. It is expected that these will be held 9:00 - 10:50 am and 2:00 - 3:50 pm on some Mondays in the first semester.

    NEUR 453 is 100% internally assessed. Students will be assessed on two oral presentations (15% each), a written summary of each oral presentation (20% each), and a letter to the editor (30%).

    Exact dates for lectures/seminars and assignments will be advised in the course outline, which will be available from the Neurosurgery Administrator.

    Teaching Arrangements

    All seminars will be taught by Professor Dirk de Ridder in rooms at Dunedin Hospital.


    Readings consist of original journal articles and reviews.

    Graduate Attributes Emphasised
    Interdisciplinary perspective, Lifelong learning, Scholarship, Communication, Critical thinking, Ethics, Information literacy, Research, Self-motivation.
    View more information about Otago's graduate attributes.
    Learning Outcomes

    Students who successfully complete this paper will

    1. Have a clear understanding that different co-existing pathophysiological explanations exist in human neuroscience (critical thinking)
    2. Have a clear understanding how philosophy influences the interpretation of experimental data, explaining the different pathophysiological models (interdisciplinary perspective)
    3. Have a clear understanding of how basic neuroscience can be translated to the clinic, either via neurosurgery or neuromodulation (interdisciplinary perspective, lifelong learning)
    4. Have a clear understanding of the strengths and weaknesses of translational neuroscience (critical thinking)
    5. Have a basic but practical understanding of the functional and structural neuroimaging techniques used in human neuroscience (scholarship, lifelong learning)
      • Functional: fMRI, PET, EEG and MEG
      • Structural: VBM, DTI/DSI/DKI
    6. Have a clear understanding of human brain activity and human brain functional connectivity from a network point of view
    7. Have a specific understanding of oscillatory activity as it relates to information processing in the human brain
    8. Have a good understanding of the different resting state and triggered networks in the brain and their interaction (scholarship)
    9. Have a clear understanding of the different existing neuromodulation methods, as applied to humans (scholarship, ethics)
      • Non-invasive: Transcranial Direct-Current Stimulation (tDCS), Transcranial Alternating Current Stimulation (TACS), Transcranial Random Noise Stimulation (tRNS), Transcranial Magnetic Stimulation (TMS), neurofeedback, Electroconvulsive Therapy (ECT)
      • Invasive: Implanted electrodes
    10. Develop skills that permit them to devise a novel neuromodulation treatment for a brain related disorder (information literacy, research, critical thinking, lifelong learning)
      • Study pathophysiological literature
      • Know which functional imaging techniques can be applied to study the pathophysiological models
      • Know non-invasive neuromodulation techniques that permit to modulate the model suggested by functional imaging
    11. Develop skill in combining information from multiple sources to produce a review of a field of human neuroscience research (research, interdisciplinary perspective, critical thinking, communication, self-motivation)
    12. Develop skill in communicating applied neuroscience (interdisciplinary perspective, communication, self-motivation)


    Semester 1

    Teaching method
    This paper is taught On Campus
    Learning management system


    Stream Days Times Weeks
    A1 Monday 09:00-10:50 9-13, 15, 18
    Monday 14:00-15:50 9-13, 15, 18
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