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    The current understanding of the neuropathophysiology of pain, including the concepts of transduction and transmission, nerve physiology, pain modulation, central nervous system changes in pain states, and chronic regional and neuropathic pain states.

    Pain science has, and is, developing very quickly. Understanding the neurobiological systems involved in the human experience of pain  assists with clinical diagnosis, management of painful disorders and knowing how to explain neurobiological information in the clinical context. This paper follows on from paper MSME 704 Introduction to Pain. It will extend students' understanding of neurobiological anatomy and physiological processes, including applicable clinical pain conditions.

    About this paper

    Paper title Neurobiology of Pain
    Subject Pain and Pain Management
    EFTS 0.125
    Points 15 points
    Teaching period Semester 2 (Distance learning)
    Domestic Tuition Fees ( NZD ) $1,469.00
    International Tuition Fees Tuition Fees for international students are elsewhere on this website.
    MSME 704 or MSMX 704
    PAIX 701
    Limited to
    MHealSc, PGCertHealSc, PGDipHealSc, PGDipPhty, MPhty

    Appropriately qualified health professionals, including medical practitioners, nurses, occupational therapists, osteopaths or physiotherapists.


    Teaching staff

    Paper Coordinator: Dr Iain Bell

    Paper Structure

    PAIN 701 consists of eight modules, covering topics that include:

    • Physiology of nociception
    • Anatomy and function of the dorsal horn
    • Pain modulation
    • Tissue-specific nociception
    • Neuropathic pain and associated factors in the nociceptive system
    • Nociplastic pain, pain vulnerability and persistent pain conditions
    Teaching Arrangements
    Material is delivered electronically and is distance taught. There are eight fortnightly online teaching sessions.

    There is no single textbook for this paper. Readings will be provided for students to access via the Library, with additional readings and other multimedia material provided via Blackboard.

    Graduate Attributes Emphasised
    Interdisciplinary perspective, Communication, Critical thinking, Information literacy, Self-motivation.
    View more information about Otago's graduate attributes.
    Learning Outcomes

    Students who successfully complete the paper will have developed an in-depth understanding of current scientific progress in pain neurobiology and the impact of these findings on clinical practice and understanding in the area of human pain experience.


    Semester 2

    Teaching method
    This paper is taught through Distance Learning
    Learning management system
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