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    The epithelial and integrative functions of the gastrointestinal and renal systems of the human body will be examined at the cellular and molecular levels. Examples of pathophysiological conditions will be highlighted.

    PHSL 233 builds on and extends the renal/urinary and gastrointestinal system topics introduced in HUBS 192.

    About this paper

    Paper title Cellular, Gastrointestinal and Renal Physiology
    Subject Physiology
    EFTS 0.15
    Points 18 points
    Teaching period Semester 2 (On campus)
    Domestic Tuition Fees ( NZD ) $1,173.30
    International Tuition Fees Tuition Fees for international students are elsewhere on this website.
    (HUBS 191 or PTWY 131) and HUBS 192 and two of BIOC 192, CELS 191, CHEM 191, PHSI 191
    MELS 251, PHCY 251, PHSL 251, PHTY 251
    Recommended Preparation
    PHSL 231
    Schedule C
    Essential for Physiology, and Functional Human Biology majors
    Teaching staff

    Convener: Dr Andrew Bahn

    Lecturers: Dr Mike Gill

    Professor Fiona McDonald

    Associate Professor Kirk Hamilton

    Associate Professor Martin Fronius

    Dr Toni-Ann Alsop

    Dr Andrew Bahn

    Please note: Teaching staff maybe subject to change.

    Paper Structure

    The lecture blocks will focus on:

    • Cellular physiology
    • Introduction to epithelia
    • Cellular communication and signaling in epithelia
    • Epithelial polarity and protein trafficking
    • Renal system
    • Gastrointestinal system

    Six laboratories will give you skills in a range of techniques:

    • Passive movement of solutes through cell membranes, osmosis
    • Glucose transport into everted sacs of the small intestine
    • The properties of epithelia
    • Renal function
    • DNA analysis of the ENaC and ROMK1 genes
    • Smooth muscle contraction


    • Internal assessment (40%) comprises two evening progress tests
    • Final examination comprises 60% of the final grade
    Teaching Arrangements
    You will attend 2 or 3 lectures each week and a laboratory session on alternate weeks.

    The primary textbook for this paper is 'Berne & Levy Physiology', 7th edn, 2018, eds. Koeppen & Stanton.

    Graduate Attributes Emphasised
    Lifelong learning, Scholarship, Communication, Critical thinking, Ethics, Research, Self-motivation, Teamwork.
    View more information about Otago's graduate attributes.
    Learning Outcomes

    Students who successfully complete this paper will:

    • Acquire extensive knowledge of the physiology of the renal and gastrointestinal systems and some pathophysiological conditions that affect epithelial tissues
    • Master skills to study epithelial characteristics
    • Develop an understanding of ethics in physiology


    Semester 2

    Teaching method
    This paper is taught On Campus
    Learning management system


    Stream Days Times Weeks
    A1 Wednesday 09:00-09:50 29, 31, 33, 35, 38, 40, 42
    Thursday 09:00-09:50 29-35, 37-42
    Friday 09:00-09:50 29-35, 37-42


    Stream Days Times Weeks
    Attend one stream from
    A1 Monday 14:00-16:50 30, 32, 34, 37, 39, 41
    A2 Thursday 14:00-16:50 30, 32, 34, 37, 39, 41
    A3 Friday 14:00-16:50 30, 32, 34, 37, 39, 41
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