Contact Details
- Phone
- 64 3 474 0999 ext 58079
- michael.williams@otago.ac.nz
University Links
- Position
- Clinical Professor
- Department
- Department of Medicine (Dunedin)
- Qualifications
- MD FRACP FACC
- Research summary
- Cardiology
- Teaching
- Integration of cardiac investigations into clinical practice.
- Clinical
-
- Echocardiography.
- Interventional cardiology.
- General cardiology.
Research
Michael Williams' research interests include studying the effect of lifestyle factors and diet on arterial function and the development of arterial disease. He has investigated the influence of physical fitness on measures of arterial inflammation and the risk of developing chest pain and heart attack in later life. His other clinical research has focussed on understanding the biology of restenosis in stents inserted in patients' heart arteries to open blockages. Studies of cardiovascular genetics have contributed to international collaborative research and the identification of novel genetic markers of arterial disease. Michael's current investigations include the regulation of gene expression on the development of narrowing and stiffening of cardiac valves with the aim of developing therapies to delay or prevent the requirement for surgical valve replacement. He is presently Chair of the Medicine Department Peer Review Committee.
Publications
Jones, G. T., Williams, M. J. A., Khashram, M., Fitzgerald, S., Lyons, O. T. A., Griffin, C. L., Lesche, S., Krysa, J., & Coffey, S. (2026). A DNA methylation marker, cg05575921 (AHRR), outperforms self-reported smoking exposure for its association with cardiovascular disease prevalence. Nicotine & Tobacco Research, 28(3), 422-428. doi: 10.1093/ntr/ntaf165 Journal - Research Article
Papannarao, J. B., Coffey, S., Gray, A., Williams, M., & Katare, R. (2025). Serial measurement of circulating cardiovascular-enriched microRNAs in patients with ischaemic heart disease: A five-year longitudinal study. Bioscience Reports, 45(12), 809-814. doi: 10.1042/bsr20253835 Journal - Research Article
Roxburgh, B., Cunningham, M., Campbell, M., Cotter, J., Williams, M., & Thomas, K. (2025). Te Waiora: Thermal therapy for cardiovascular health. Heart, Lung & Circulation, 34(Suppl. 3), O28. doi: 10.1016/j.hlc.2025.05.029 Conference Contribution - Published proceedings: Abstract
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Williams, M. J. A., Gwynne-Jones, D., & Thomas, K. N. (2025). Three practical methods for estimating preoperative cardiorespiratory fitness in patients with severe hip or knee osteoarthritis: A cross-sectional study. Arthritis Care & Research. Advance online publication. doi: 10.1002/acr.25703 Journal - Research Article
Deo, N., Siddiqui, H., Peppercorn, K., Madani, G., Rutherford-Blyth, A., Rutledge, M., Williams, M. J. A., McCormick, S. P. A., & Redpath, G. M. I. (2025). Antidepressants stimulate lipoprotein(a) macropinocytosis via serotonin-enhanced cell surface binding. Journal of Lipid Research, 66(10), 100889. doi: 10.1016/j.jlr.2025.100889 Journal - Research Article
2026
Journal - Research Article
Jones, G. T., Williams, M. J. A., Khashram, M., Fitzgerald, S., Lyons, O. T. A., Griffin, C. L., Lesche, S., Krysa, J., & Coffey, S. (2026). A DNA methylation marker, cg05575921 (AHRR), outperforms self-reported smoking exposure for its association with cardiovascular disease prevalence. Nicotine & Tobacco Research, 28(3), 422-428. doi: 10.1093/ntr/ntaf165
2025
Journal - Research Article
Papannarao, J. B., Coffey, S., Gray, A., Williams, M., & Katare, R. (2025). Serial measurement of circulating cardiovascular-enriched microRNAs in patients with ischaemic heart disease: A five-year longitudinal study. Bioscience Reports, 45(12), 809-814. doi: 10.1042/bsr20253835
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Williams, M. J. A., Gwynne-Jones, D., & Thomas, K. N. (2025). Three practical methods for estimating preoperative cardiorespiratory fitness in patients with severe hip or knee osteoarthritis: A cross-sectional study. Arthritis Care & Research. Advance online publication. doi: 10.1002/acr.25703
Deo, N., Siddiqui, H., Peppercorn, K., Madani, G., Rutherford-Blyth, A., Rutledge, M., Williams, M. J. A., McCormick, S. P. A., & Redpath, G. M. I. (2025). Antidepressants stimulate lipoprotein(a) macropinocytosis via serotonin-enhanced cell surface binding. Journal of Lipid Research, 66(10), 100889. doi: 10.1016/j.jlr.2025.100889
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Williams, M. J. A., Gwynne-Jones, D. P., & Thomas, K. N. (2025). The effect of pre-operative cardiorespiratory fitness on functional and subjective outcomes following total hip and knee arthroplasty: A single centre, observational study. New Zealand Medical Journal/Te ara tika o te hauora hapori, 138(1614), 19-41. doi: 10.26635/6965.6855
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Williams, M. J. A., & Thomas, K. N. (2025). Both hot- and thermoneutral-water immersion reduce 24-h blood pressure in people with hypertension: A randomized crossover study. Temperature, 12(2), 166-178. doi: 10.1080/23328940.2025.2465025
Moore, M. K., Jones, G. T., Whalley, G., Williams, M. J. A., Stewart, R. A., & Coffey, S. (2025). The prevalence of aortic stenosis in Maōri undergoing clinically indicated echocardiography compared to New Zealand Europeans. New Zealand Medical Journal/Te ara tika o te hauora hapori, 138(1608), 84-93. Retrieved from https://www.nzmj.org.nz/
Conference Contribution - Published proceedings: Abstract
Roxburgh, B., Cunningham, M., Campbell, M., Cotter, J., Williams, M., & Thomas, K. (2025). Te Waiora: Thermal therapy for cardiovascular health. Heart, Lung & Circulation, 34(Suppl. 3), O28. doi: 10.1016/j.hlc.2025.05.029
2024
Journal - Research Article
Moore, M. K., Jones, G. T., McCormick, S., Williams, M. J. A., & Coffey, S. (2024). Association between lipoprotein(a), LPA genetic risk score, aortic valve disease, and subsequent major adverse cardiovascular events. European Journal of Preventive Cardiology, 31, 1303-1311. doi: 10.1093/eurjpc/zwae100
Moore, M. K., Jones, G. T., Whalley, G., Prendergast, B., Williams, M. J. A., & Coffey, S. (2024). Outcomes of patients with early calcific aortic valve disease detected by clinically indicated echocardiography. European Heart Journal: Cardiovascular Imaging, 25, 356-364. doi: 10.1093/ehjci/jead259
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Williams, M. J. A., Gwynne-Jones, D., & Thomas, K. N. (2024). Upper-limb high-intensity interval training or passive heat therapy to optimise cardiorespiratory fitness prior to total hip or knee arthroplasty: A randomised controlled trial. Arthritis Care & Research, 76(3), 393-402. doi: 10.1002/acr.25238
Conference Contribution - Published proceedings: Abstract
Moore, M. K., Jones, G. T., Whalley, G., Prendergast, B. D., Williams, M. J. A., & Coffey, S. (2024). Cardiac damage predicts the outcome of calcific aortic valve disease regardless of the severity of aortic stenosis. European Heart Journal, 45(Suppl. 1), ehae666.1881. doi: 10.1093/eurheartj/ehae666.1881
Bellae Papannarao, J., Coffey, S., Gray, A., Williams, M., & Katare, R. (2024). Serial measurement of circulating cardiovascular enriched miR-1 and -34a reflects the changes in cardiac function in patients with ischemic heart disease: A five year follow-up study. Circulation Research, 135(Suppl. 1), Tu147. doi: 10.1161/res.135.suppl_1.Tu147
Moore, M., Jones, G., Whalley, G., Stewart, R., Williams, M., & Coffey, S. (2024). The prevalence of aortic stenosis in Māori undergoing clinically indicated echocardiography. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S93). doi: 10.1016/j.hlc.2024.04.296
Tonkin, D., Schwenke, D., Williams, M., & Katare, R. (2024). Investigating microRNA therapeutics in a 3D model of the failing heart. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S70). doi: 10.1016/j.hlc.2024.04.245
Conference Contribution - Poster Presentation (not in published proceedings)
Tonkin, D., Williams, M., Schwenke, D., & Katare, R. (2024, August-September). Investigating microRNA therapeutics in a 3D model of the failing heart. Poster session presented at the 18th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2023
Journal - Research Article
Siddiqui, H., Deo, N., Rutledge, M. T., Williams, M. J. A., Redpath, G. M. I., & McCormick, S. P. A. (2023). Plasminogen receptors promote lipoprotein(a) uptake by enhancing surface binding and facilitating macropinocytosis. Arteriosclerosis, Thrombosis, & Vascular Biology, 43, 1851-1866. doi: 10.1161/atvbaha.123.319344
Kerr, A. J., Choi, Y., Williams, M. J. A., Stewart, R. A. H., White, H. D., Devlin, G., … Adamson, P. D., Fairley, S., … Poppe, K. (2023). Paired risk scores to predict ischaemic and bleeding risk twenty-eight days to one year after an acute coronary syndrome. Heart, 109(24), 1827-1836. doi: 10.1136/heartjnl-2023-322830
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Williams, M. J. A., Gwynne-Jones, D., & Thomas, K. N. (2023). Acute and adaptive cardiovascular and metabolic effects of passive heat therapy or high-intensity interval training in patients with severe lower-limb osteoarthritis. Physiological Reports, 11, e15699. doi: 10.14814/phy2.15699
Barrett-Young, A., Ambler, A., Cheyne, K., Guiney, H., Kokaua, J., Tham, Y. C., Williams, M. J. A., Wilson, G. A., … Poulton, R. (2023). Childhood social isolation as a predictor of retinal neuronal thickness in middle age: A lifecourse birth cohort study. Psychosomatic Medicine, 85, 238-249. doi: 10.1097/psy.0000000000001177
Conference Contribution - Published proceedings: Abstract
Sneddon, K., McLeod, P., Williams, M., & Coffey, S. (2023). Overcoming barriers to recruitment of an older heart valve population. Heart, Lung & Circulation, 32(Suppl. 2), P68. doi: 10.1016/j.hlc.2023.04.289
Moore, M., Jones, G., McCormick, S., Williams, M., & Coffey, S. (2023). Association between lipoprotein(a), LPA genetic risk score, aortic valve disease, and subsequent major adverse cardiovascular events. Heart, Lung & Circulation, 32(Suppl. 2), P66. doi: 10.1016/j.hlc.2023.04.287
Conference Contribution - Poster Presentation (not in published proceedings)
Bellae Papannarao, J., Coffey, S., Williams, M., McLelland, M., & Katare, R. (2023, August). Circulating microRNAs as prognostic biomarkers for ischemic heart disease. Poster session presented at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Tonkin, D., Williams, M., Schwenke, D., & Katare, R. (2023, August). Effects of synthetic miRNA cocktail for activation of endogenous progenitor cells in the diabetic heart. Verbal presentation at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Bingham, K. T., Fomison-Nurse, I. C., de Jonge, W., van Hout, I., Davis, P. J., Lim, L., Bunton, R. W., Williams, M. J. A., Coffey, S., & Lamberts, R. R. (2023, August). From fat to fibrillation: Investigating the relationship between epicardial adipose tissue, atrial fibrillation, and obesity. Verbal presentation at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2022
Journal - Research Article
McLeod, P., Coffey, S., Sneddon, K., Williams, M., Kerr, A., & Pemberton, J. (2022). Clinically acquired high sensitivity cardiac troponin T is a poor predictor of reduced left ventricular ejection fraction after ST elevation myocardial infarction: A national cohort study–ANZACS-QI 65. Heart, Lung & Circulation, 31, 1513-1523. doi: 10.1016/j.hlc.2022.07.014
Ghosh, N., Fenton, S., van Hout, I., Jones, G. T., Coffey, S., Williams, M. J. A., Sugunesegran, R., Parry, D., … Schwenke, D. O., Chatterjee, A., & Katare, R. (2022). Therapeutic knockdown of miR-320 improves deteriorated cardiac function in a pre-clinical model of non-ischemic diabetic heart disease. Molecular Therapy: Nucleic Acids, 29, 330-342. doi: 10.1016/j.omtn.2022.07.007
Journal - Research Other
Pons, A., Whalley, G., Sneddon, K., Williams, M., & Coffey, S. (2022). A systematic review of non-procedural contributors to quality of life in heart valve disease. Health Sciences Review, 4, 100050. doi: 10.1016/j.hsr.2022.100050
Pons, A., Whalley, G., Sneddon, K., Williams, M., & Coffey, S. (2022). Predictors of quality of life after revascularization for ischemic heart disease: A systematic review. Health Sciences Review, 2, 100017. doi: 10.1016/j.hsr.2022.100017
Conference Contribution - Published proceedings: Abstract
Roxburgh, B. H., Campbell, H., Cotter, J. D., Reymann, U., Gwynne-Jones, D., Williams, M. J. A., & Thomas, K. N. (2022). The effect of high-intensity interval training and heat therapy on cardiorespiratory fitness in patients with severe lower-limb osteoarthritis. Journal of Sport & Exercise Science, 6(4), (pp. 36-37). doi: 10.36905/jses.2022.04.01
Ismail, L., Black, M., Williams, M., Coassin, S., Forer, L., Kronenberg, F., & McCormick, S. (2022). Variants in solute cation transporters 3 associate with high Lp(a) levels independent of apo(a) isoform size. Circulation, 146(Suppl. 1), 12528. doi: 10.1161/circ.146.suppl_1.13062
Ismail, L., Black, M., Cadzow, M., Merriman, T., Williams, M., & McCormick, S. (2022). Two variants are associated with high lipoprotein (a) levels independent of apolipoprotein (a) isoform size. Proceedings of the ComBio Conference. (pp. 169). Retrieved from https://combio.org.au/combio2022/
Roxburgh, B., Campbell, H., Cotter, J., Reymann, U., Gwynne-Jones, D., Williams, M., & Thomas, K. (2022). The effect of heat therapy and high-intensity interval training on cardiometabolic health in patients with severe lower-limb osteoarthritis. Heart, Lung & Circulation, 31(Suppl. 3), (pp. S42). doi: 10.1016/j.hlc.2022.06.012
Moore, M., McLeod, P., Whalley, G., Williams, M., Jones, G., & Coffey, S. (2022). Long-term outcomes of aortic sclerosis in patients undergoing clinically indicated echocardiography. Heart, Lung & Circulation, 31(Suppl. 2), (pp. S23). doi: 10.1016/j.hlc.2022.05.008
Conference Contribution - Poster Presentation (not in published proceedings)
Tonkin, D., Williams, M., Schwenke, D., & Katare, R. (2022, August-September). Effects of synthetic miRNA cocktail for activation of endogenous progenitor cells in the diabetic heart. Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Bingham, K. T., Fomison-Nurse, I. C., de Jonge, W., van Hout, I., Parry, D. J., Williams, M. J. A., Coffey, S., & Lamberts, R. R. (2022, August-September). Effect of obesity on human epicardial adipose tissue induced arrhythmic susceptibility in human atrial myocardium. Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Jones, G. T., Bhat, B., Williams, M. J. A., Coffey, S., Lesche, S., Hill, B. G., & Krysa, J. (2022, August). Accelerated DNA methylation epigenetic age in vascular disease. Verbal presentation at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
2021
Journal - Research Article
Pasupathy, S., Lindahl, B., Litwin, P., Tavella, R., Williams, M. J. A., Air, T., … Beltrame, J. F. (2021). Survival in patients with suspected myocardial infarction with nonobstructive coronary arteries: A comprehensive systematic review and meta-analysis from the MINOCA Global Collaboration. Circulation: Cardiovascular Quality & Outcomes, 14(11), e007880. doi: 10.1161/circoutcomes.121.007880
Coffey, S., Dixit, P., Saw, E. L., Babakr, A. A., van Hout, I., Galvin, I. F., Saxena, P., Bunton, R. W., Davis, P. J., Lamberts, R. R., Katare, R., & Williams, M. J. A. (2021). Thiamine increases resident endoglin positive cardiac progenitor cells and atrial contractile force in humans: A randomised controlled trial. International Journal of Cardiology, 341, 70-73. doi: 10.1016/j.ijcard.2021.08.039
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Williams, M. J. A., Gwynne-Jones, D., & Thomas, K. N. (2021). The absolute and relative reliability of hand-held dynamometry in patients with severe lower-limb osteoarthritis scheduled for total joint replacement surgery. International Journal of Research in Exercise Physiology, 16(2), 81-91. Retrieved from https://ijrep.org
Aitken-Buck, H. M., Krause, J., van Hout, I., Davis, P. J., Bunton, R. W., Parry, D. J., Williams, M. J. A., Coffey, S., … Jones, P. P., & Lamberts, R. R. (2021). Long-chain acylcarnitine 18:1 acutely increases human atrial myocardial contractility and arrhythmia susceptibility. American Journal of Physiology: Heart & Circulatory Physiology, 321, H162-H174. doi: 10.1152/ajpheart.00184.2021
Ho, C. Y.-C., Lee, M., El-Jack, S., Barr, P., Simmonds, M., Devlin, G., Adamson, P. D., Williams, M., & Kerr, A. J. (2021). How common are non-acute coronary syndrome (ACS) diagnoses in patients with suspected ACS investigated with coronary angiography in New Zealand? (ANZACS-QI 58). New Zealand Medical Journal, 134(1537), 43-55. Retrieved from https://www.nzma.org.nz/journal
Williams, M. J. A., Lee, M., Alfadhel, M., & Kerr, A. J. (2021). Obesity and all cause mortality following acute coronary syndrome (ANZACS QI 53). Heart, Lung & Circulation, 30, 1854-1862. doi: 10.1016/j.hlc.2021.04.014
Purvis, N., Kumari, S., Chandrasekera, D., Bellae Papannarao, J., Gandhi, S., van Hout, I., Coffey, S., Bunton, R., Sugunesegran, R., Parry, D., Davis, P., Williams, M. J. A., Bahn, A., & Katare, R. (2021). Diabetes induces dysregulation of microRNAs associated with survival, proliferation and self-renewal in cardiac progenitor cells. Diabetologia, 64, 1422-1435. doi: 10.1007/s00125-021-05405-7
Saw, E. L., Pearson, J. T., Schwenke, D. O., Munasinghe, P. E., Tsuchimochi, H., Rawal, S., Coffey, S., … Bunton, R., Van Hout, I., … Williams, M. J. A., … Fronius, M., & Katare, R. (2021). Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications. Cardiovascular Diabetology, 20, 50. doi: 10.1186/s12933-021-01231-8
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Williams, M. J. A., Gwynne-Jones, D., & Thomas, K. N. (2021). Cardiopulmonary exercise testing in severe osteoarthritis: A crossover comparison of four exercise modalities. Anaesthesia, 76, 72-81. doi: 10.1111/anae.15162
Conference Contribution - Published proceedings: Abstract
Chan, D., Stewart, R., Kerr, A., Dicker, B., Kyle, C., Adamson, P., … Edmond, J., … Elliott, J., … Williams, M., … Somaratne, J. (2021). The impact of a national COVID-19 lockdown on acute coronary syndrome hospitalisations in New Zealand: An ANZACS-QI study. Heart, Lung & Circulation, 30(Suppl. 2), (pp. S62-S63). doi: 10.1016/j.hlc.2021.05.013
Ismail, L., Black, M., Jones, G., Williams, M., & McCormick, S. (2021). Identifying functional variants associated with high lipoprotein (a) phenotypes. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 55). Retrieved from https://www.faobmb2021.org
Mbizvo, R., Alfadhel, M., Williams, M. J. A., Coffey, S., Kerr, A., Webster, M., & Lee, M. (2021). A contemporary presentation of the incidence and management of spontaneous coronary artery dissection (SCAD) in New Zealand: An ANZACS-QI study. European Heart Journal, 42(Suppl. 1), (pp. 1306). doi: 10.1093/eurheartj/ehab724.1306
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Gwynne-Jones, D., Williams, M. J. A., & Thomas, K. N. (2021). The effect of heat therapy and high-intensity interval training on fitness, blood pressure and osteoarthritis impact in patients with severe lower-limb osteoarthritis. New Zealand Medical Journal, 134(1547), (pp. 136). Retrieved from https://www.nzma.org.nz/journal
Aitken-Buck, H. M., van Hout, I., Krause, J., Davis, P. J., Bunton, R. W., Parry, D. J., Williams, M. J. A., Coffey, S., … Jones, P. P., & Lamberts, R. R. (2021). Arrhythmogenic and inotropic effects of long-chain acylcarnitines in the human heart. New Zealand Medical Journal, 134(1537), (pp. 111-112). Retrieved from https://www.nzma.org.nz/journal
Bir, S., Chandrasekera, D., Van Hout, I., Lequeux, S., Coffey, S., Bunton, R. W., Davis, P., Williams, M. J. A., & Katare, R. (2021). Use of exosomes to deliver proangiogenic microRNAs and reduce the microvascular complications of diabetes mellitus. Proceedings of the 44th New Zealand Society for the Study of Diabetes (NZSSD) Annual Scientific Meeting. Retrieved from https://www.ivvy.com.au/event/NZSSD2021
2020
Journal - Research Article
Chan, D. Z. L., Stewart, R. A. H., Kerr, A. J., Dicker, B., Kyle, C. V., Adamson, P. D., … Edmond, J., … Elliott, J. M., … Swain, A. H., … Williams, M. J. A., … Somaratne, J. B. (2020). The impact of a national COVID-19 lockdown on acute coronary syndrome hospitalisations in New Zealand (ANZACS-QI 55). Lancet Regional Health: Western Pacific, 5, 100056. doi: 10.1016/j.lanwpc.2020.100056
Jones, G. T., Drinkwater, B., Blake-Barlow, A., Hill, G. B., Williams, M. J. A., Krysa, J., van Rij, A. M., & Coffey, S. (2020). Both small and large infrarenal aortic size is associated with an increased prevalence of ischaemic heart disease. European Journal of Vascular & Endovascular Surgery, 60, 594-601. doi: 10.1016/j.ejvs.2020.06.025
Aitken-Buck, H. M., Babakr, A. A., Fomison-Nurse, I. C., van Hout, I., Davis, P. J., Bunton, R. W., Williams, M. J. A., Coffey, S., Jones, P. P., & Lamberts, R. R. (2020). Inotropic and lusitropic, but not arrhythmogenic, effects of adipocytokine resistin on human atrial myocardium. American Journal of Physiology: Endocrinology & Metabolism, 319, E540-E547. doi: 10.1152/ajpendo.00202.2020
Moharram, M. A., Aitken-Buck, H. M., Reijers, R., van Hout, I., Williams, M. J. A., Jones, P. P., Whalley, G. A., Lamberts, R. R., & Coffey, S. (2020). Correlation between epicardial adipose tissue and body mass index in New Zealand ethnic populations. New Zealand Medical Journal, 133(1516), 22-32. Retrieved from https://www.nzma.org.nz/journal
Chandrasekera, D. N. K., Neale, J. P. H., van Hout, I., Rawal, S., Coffey, S., Jones, G. T., … Manning, P., Williams, M. J. A., & Katare, R. (2020). Upregulation of microRNA-532 enhances cardiomyocyte apoptosis in the diabetic heart. Apoptosis, 25(5-6), 388-399. doi: 10.1007/s10495-020-01609-1
Wang, T. K. M., Kasargod, C., Chan, D., Cicovic, S., Dimalapang, E., Webster, M., … Smyth, D., Williams, M., … Somaratne, J. (2020). Diagnostic coronary angiography and percutaneous coronary intervention practices in New Zealand: The All New Zealand Acute Coronary Syndrome-Quality Improvement CathPCI Registry 3-year study (ANZACS- QI 37). International Journal of Cardiology, 312, 37-41. doi: 10.1016/j.ijcard.2020.02.063
Moharram, M. A., Wilson, L. C., Williams, M. J. A., & Coffey, S. (2020). Beat-to-beat blood pressure measurement using a cuffless device does not accurately reflect invasive blood pressure. International Journal of Cardiology Hypertension, 5, 100030. doi: 10.1016/j.ijchy.2020.100030
Jones, G. T., Marsman, J., Bhat, B., Phillips, V. L., Chatterjee, A., Rodger, E. J., Williams, M. J. A., van Rij, A. M., & McCormick, S. P. A. (2020). DNA methylation profiling identifies a high effect genetic variant for lipoprotein(a) levels. Epigenetics, 15(9), 949-958. doi: 10.1080/15592294.2020.1739797
Babakr, A. A., Fomison-Nurse, I. C., van Hout, I., Aitken-Buck, H. M., Sugunesegran, R., Davis, P. J., Bunton, R. W., Williams, M. J. A., Coffey, S., Stiles, M. K., Jones, P. P., & Lamberts, R. R. (2020). Acute interaction between human epicardial adipose tissue and human atrial myocardium induce arrhythmic susceptibility. American Journal of Physiology: Endocrinology & Metabolism, 318, E164-E172. doi: 10.1152/ajpendo.00374.2019
Morgan, B. M., Brown, A. N., Deo, N., Harrop, T. W. R., Taiaroa, G., Mace, P. D., Wilbanks, S. M., Merriman, T. R., Williams, M. J. A., & McCormick, S. P. A. (2020). Nonsynonymous SNPs in LPA homologous to plasminogen deficiency mutants represent novel null apo(a) alleles. Journal of Lipid Research, 61, 432-444. doi: 10.1194/jlr.M094540
Lal, S., Gray, A., Kim, E., Bunton, R. W., Davis, P., Galvin, I. F., & Williams, M. J. A. (2020). Frailty in elderly patients undergoing cardiac surgery increases hospital stay and 12-month readmission rate. Heart, Lung & Circulation, 29, 1187-1194. doi: 10.1016/j.hlc.2019.10.007
Hancox, R. J., Thomas, L., Williams, M. J. A., & Sears, M. R. (2020). Associations between lung and endothelial function in early middle age. Respirology, 25, 89-96. doi: 10.1111/resp.13556
Journal - Research Other
Coffey, S., Moynagh, A., Green, B., Edmond, J., Wilkins, G. T., Pemberton, J., … Williams, M. J. A., & Arnold, B. (2020). Changes to management of a non-pandemic illness during the COVID-19 pandemic: Case study of invasive management of acute coronary syndrome. New Zealand Medical Journal, 133(1513), 101-106. Retrieved from https://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Ghosh, N., Weeks, R., Day, R., van Hout, I., Coffey, S., Williams, M. J., Davis, P., Chatterjee, A., & Katare, R. (2020). Therapeutic modulation of microRNA-320 using CRISPR/Cas9 to prevent apoptosis in high glucose cultured human ventricular cardiomyocytes. Proceedings of the Genetics Otago (GO) Epigenetics User Group (EUG) Symposium. Retrieved from https://blogs.otago.ac.nz/go/2020-3/
Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Gwynne-Jones, D., Williams, M. J. A., & Thomas, K. N. (2020). A crossover comparison of four cardiopulmonary exercise testing modalities in severe lower-limb osteoarthritis patients. New Zealand Medical Journal, 133(1527), (pp. 127). Retrieved from https://www.nzma.org.nz/journal
Roxburgh, B. H., Campbell, H., Cotter, J. D., Reymann, U., Gwynne-Jones, D., Williams, M. J. A., & Thomas, K. N. (2020). The effect of passive heat therapy on body composition and isometric muscle strength in patients with severe lower-limb osteoarthritis. Journal of Sport & Exercise Science, 4(3), (pp. 32). doi: 10.36905/jses.2020.03.01
Moharram, M., van Hout, I., Jones, P., Lamberts, R., Whalley, G., Williams, M., & Coffey, S. (2020). Speckle tracking strain analysis for the detection of changes in left ventricular function in patients with hypertension. Heart, Lung & Circulation, 29(Suppl. 1), (pp. S18). doi: 10.1016/j.hlc.2020.05.048
Conference Contribution - Verbal presentation and other Conference outputs
Roxburgh, B. H., Campbell, H., Cotter, J. D., Reymann, U., Gwynne-Jones, D., Williams, M. J. A., & Thomas, K. N. (2020, December). The effect of passive heat therapy on body composition and isometric muscle strength in patients with severe lower-limb osteoarthritis. Verbal presentation at the School of Physiotherapy Postgraduate Research Symposium, Dunedin, New Zealand.
2019
Journal - Research Article
Aitken-Buck, H. M., Moharram, M., Babakr, A. A., Reijers, R., Van Hout, I., Fomison-Nurse, I. C., Sugunesegran, R., … Bunton, R. W., Williams, M. J. A., … Jones, P. P., Coffey, S., & Lamberts, R. R. (2019). Relationship between epicardial adipose tissue thickness and epicardial adipocyte size with increasing body mass index. Adipocyte, 8(1), 412-420. doi: 10.1080/21623945.2019.1701387
Kerr, A. J., Lee, M., Grey, C., Pegg, T. J., Fisher, N. G., White, H. H., … Williams, M. J. A., Smyth, D., … on behalf of the ANZACS-QI investigators. (2019). Acute reperfusion for ST-elevation myocardial infarction in New Zealand (2015-2017): Patient and system delay (ANZACS-QI 29). New Zealand Medical Journal, 132(1498), 41-59. Retrieved from https://www.nzma.org.nz/journal
Kerr, A. J., Lee, M., Jiang, Y., Grey, C., Wells, S., Williams, M., … on behalf of the ANZACS-QI Investigators. (2019). High level of capture of coronary intervention and associated acute coronary syndromes in the all New Zealand acute coronary syndrome quality improvement cardiac registry and excellent agreement with national administrative datasets (ANZACS-QI 25). New Zealand Medical Journal, 132(1492), 19-29. Retrieved from https://www.nzma.org.nz/journal
Rawal, S., Nagesh, P. T., Coffey, S., Van Hout, I., Galvin, I. F., Bunton, R. W., Davis, P., Williams, M. J. A., & Katare, R. (2019). Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium. Cardiovascular Diabetology, 18, 13. doi: 10.1186/s12933-019-0814-4
Ellis, C. J., Gamble, G. D., Williams, M. J. A., Matsis, P., Elliott, J. M., Devlin, G., Mann, S., … for the Regional Cardiac Society NZ ACS Audit Group, including Richards, M., & Nixon, G. (2019). All-cause mortality following an acute coronary syndrome: 12-year follow-up of the comprehensive 2002 New Zealand Acute Coronary Syndrome Audit. Heart, Lung & Circulation, 28(2), 245-256. doi: 10.1016/j.hlc.2017.10.015
Jones, G. T., Sandiford, P., Hill, G. B., Williams, M. J. A., Khashram, M., Tilyard, M. W., Hammond-Tooke, G. D., Krysa, J., & van Rij, A. M. (2019). Correcting for body surface area identifies the true prevalence of abdominal aortic aneurysm in screened women. European Journal of Vascular & Endovascular Surgery, 57(2), 221-228. doi: 10.1016/j.ejvs.2018.08.048
Williams, M. J. A., Barr, P. R., Lee, M., Poppe, K. K., & Kerr, A. J. (2019). Outcome after myocardial infarction without obstructive coronary artery disease. Heart, 105(7), 524-530. doi: 10.1136/heartjnl-2018-313665
Journal - Research Other
Moharram, M. A., Lamberts, R. R., Whalley, G., Williams, M. J. A., & Coffey, S. (2019). Myocardial tissue characterisation using echocardiographic deformation imaging. Cardiovascular Ultrasound, 17, 27. doi: 10.1186/s12947-019-0176-9
Conference Contribution - Published proceedings: Abstract
Roxburgh, B. H., Campbell, H., Cotter, J. D., Reymann, U., Gwynne-Jones, D., Williams, M. J. A., & Thomas, K. N. (2019). A crossover comparison of four cardiopulmonary exercise testing modalities in severe lower-limb osteoarthritis patients. Journal of Sport & Exercise Science, 3(1), (pp. 32). doi: 10.36905/jses.2019.01.01
Pasupathy, S., Lindahl, B., Litwin, P., Tavella, R., Williams, M., Air, T., … Beltrame, J. (2019). Survival after myocardial infarction with non-obstructive coronary arteries (MINOCA): A comprehensive systematic review and meta-analysis. European Heart Journal, 40(Suppl. 1), (pp. 1366). doi: 10.1093/eurheartj/ehz748.0147
Litwin, P., Pasupathy, S., Lindahl, B., Tavella, R., Williams, M., Air, T., & MINOCA Global Collaboration. (2019). Prognosis of myocardial infarction with non-obstructive coronary arteries: A systematic review. Heart, Lung & Circulation, 28(Suppl. 4), (pp. S313-S314). doi: 10.1016/j.hlc.2019.06.415
Aitken-Buck, H. M., Moharram, M., Babakr, A., van Hout, I., Fomison-Nurse, I., Reijers, R., … Williams, M., Jones, P., Coffey, S., & Lamberts, R. (2019). Increasing general adiposity is not associated with hypertrophy of epicardial adipocytes in cardiac surgery patients. Heart, Lung & Circulation, 28(Suppl. 4), (pp. S177). doi: 10.1016/j.hlc.2019.06.101
Moharram, M., Aitken-Buck, H., Van Hout, I., Reijers, R., Williams, M., Whalley, G., Jones, P., Lamberts, R., & Coffey, S. (2019). Impact of ethnicity on the correlation between body mass index and epicardial adipose tissue. Heart, Lung & Circulation, 28(Suppl. 4), (pp. S251). doi: 10.1016/j.hlc.2019.06.276
Alfadhel, M., Pemberton, J., Williams, M. J. A., Pattison, S., McDiarmid, B., Pemberton, L., Whalley, G., & Coffey, S. (2019). Imaging guidelines adherence for chemotherapy-related cardiotoxicity: A retrospective study. Heart, Lung & Circulation, 28(Suppl. 1), (pp. S25). doi: 10.1016/j.hlc.2019.05.065
2018
Journal - Research Article
Shearer, D. M., Thomson, W. M., Cameron, C. M., Ramrakha, S., Wilson, G., Wong, T. Y., Williams, M. J. A., McLean, R., Theodore, R., & Poulton, R. (2018). Periodontitis and multiple markers of cardiometabolic risk in the fourth decade: A cohort study. Community Dentistry & Oral Epidemiology, 46(6), 615-623. doi: 10.1111/cdoe.12414
Fomison-Nurse, I., Saw, E. E. L., Gandhi, S., Munasinghe, P. E., Van Hout, I., Williams, M. J. A., Galvin, I., Bunton, R., Davis, P., Cameron, V., & Katare, R. (2018). Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells. Cell Death & Differentiation, 25, 1336-1349. doi: 10.1038/s41418-017-0047-6
Conference Contribution - Published proceedings: Abstract
Alfadhel, M., Kerr, A., Lee, M., & Williams, M. (2018). The effect of body mass index on clinical outcomes in patients with acute coronary syndrome. JACC, 72(13, Suppl.), (pp. B169-B170). doi: 10.1016/j.jacc.2018.08.1583
Alfadhel, M., Lee, M., Kerr, A., & Williams, M. J. A. (2018). Body mass index and clinical outcomes in patients with acute coronary syndrome. Heart, Lung & Circulation, 27(Suppl. 1), (pp. S6). doi: 10.1016/j.hlc.2018.05.113
Stevenson, A. J., Williams, M. J. A., & Jones, G. T. (2018). Post-hoc epigenome-wide association analyses validating differential DNA methylation patterns related to age, diabetes and smoking. New Zealand Medical Journal, 131(1470), (pp. 112). Retrieved from https://www.nzma.org.nz/journal
2017
Journal - Research Article
Kerr, A. J., Williams, M., White, H., Grey, C., Jiang, Y., Nunn, C., on behalf of the ANZACS-QI investigators. (2017). 30-day mortality aft er percutaneous coronary intervention in New Zealand public hospitals (ANZACS-QI 18). New Zealand Medical Journal, 130(1459), 54-63. Retrieved from http://www.nzma.org.nz/journal
Williams, M. J. A., Milne, B. J., Ambler, A., Theodore, R., Ramrakha, S., Caspi, A., Moffitt, T. E., & Poulton, R. (2017). Childhood body mass index and endothelial dysfunction evaluated by peripheral arterial tonometry in early midlife. International Journal of Obesity, 41, 1355-1360. doi: 10.1038/ijo.2017.108
Wilson, L. C., Peebles, K. C., Hoye, N. A., Manning, P., Sheat, C., Williams, M. J. A., Wilkins, G. T., Wilson, G. A., & Baldi, J. C. (2017). Resting heart rate variability and exercise capacity in Type 1 diabetes. Physiological Reports, 5(8), e13248. doi: 10.14814/phy2.13248
Elliott, J. M., Wang, T. K. M., Gamble, G., Williams, M., Matsis, P., Troughton, R., … Mann, S., Richards, M., … Ellis, C. (2017). A decade of improvement in the management of New Zealand ST-elevation myocardial infarction (STEMI) patients: Results from the New Zealand Acute Coronary Syndrome (ACS) Audit Group national audits of 2002, 2007 and 2012. New Zealand Medical Journal, 130(1453), 17-28. Retrieved from https://www.nzma.org.nz/journal
Rawal, S., Munasinghe, E. P., Nagesh, P. T., Lew, J. K. S., Jones, G. T., Williams, M. J. A., Davis, P., Bunton, R. W., Galvin, I. F., Manning, P., Lamberts, R. R., & Katare, R. (2017). Downregulation of miR-15a/b accelerates fibrotic remodelling in the Type-2 diabetic human and mouse heart. Clinical Science, 131(9), 847-863. doi: 10.1042/cs20160916
Rawal, S., Munasinghe, P. E., Shindikar, A., Paulin, J., Cameron, V., Manning, P., Williams, M. J. A., Jones, G. T., Bunton, R., Galvin, I., & Katare, R. (2017). Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. Cardiovascular Research, 113(1), 90-101. doi: 10.1093/cvr/cvw235
Sharma, M., Redpath, G. M., Williams, M. J. A., & McCormick, S. P. A. (2017). Recycling of apolipoprotein(a) after PlgRKT-mediated endocytosis of lipoprotein(a). Circulation Research, 120(7), 1091-1102. doi: 10.1161/circresaha.116.310272
Jones, G. T., Tromp, G., Kuivaniemi, H., Gretarsdottir, S., Baas, A. F., Giusti, B., … Phillips, L. V., Williams, M. J. A., Wei, W., … Thomson, I. A., Krysa, J., Hill, G. B., Roake, J., Merriman, T. R., … van Rij, A., … Bown, M. J. (2017). Meta-analysis of genome-wide association studies for abdominal aortic aneurysm identifies four new disease-specific risk loci. Circulation Research, 120, 341-353. doi: 10.1161/circresaha.116.308765
Journal - Research Other
Ram, T. P., Fomison-Nurse, I., Gandhi, S., Coffey, S., Saxena, P., Galvin, I., Bunton, R., Williams, M. J. A., Lamberts, R. R., & Katare, R. (2017). The diagnostic sensitivity of circulating cardio-enriched microRNAs is increased after normalization of high-density lipoprotein levels [Short communication]. International Journal of Cardiology, 236, 498-500. doi: 10.1016/j.ijcard.2017.01.119
Conference Contribution - Published proceedings: Abstract
Williams, M. J. A., Barr, P. R., Lee, M., & Kerr, A. J. (2017). Myocardial infarction with non-obstructive coronary artery disease: Not a benign condition. Heart, Lung & Circulation, 26(Suppl. 1), (pp. S23). doi: 10.1016/j.hlc.2017.05.060
Lal, S., Gray, A., Kim, E., Galvin, I., Bunton, R., Davis, P., & Williams, M. (2017). Frailty in elderly patients undergoing cardiac surgery increases hospital stay. Heart, Lung & Circulation, 26(Suppl. 1), (pp. S40-S41). doi: 10.1016/j.hlc.2017.05.109
Conference Contribution - Verbal presentation and other Conference outputs
Coffey, S., Williams, M. J. A., Phillips, L. V., Galvin, I. F., Bunton, R. W., & Jones, G. T. (2017, September). MicroRNA based investigations into the biology of aortic valve stenosis. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2016
Journal - Research Article
Coffey, S., Williams, M. J. A., Phillips, L. V., Galvin, I. F., Bunton, R. W., & Jones, G. T. (2016). Integrated microRNA and messenger RNA analysis in aortic stenosis. Scientific Reports, 6, 36904. doi: 10.1038/srep36904
Kerr, A. J., Williams, M. J. A., Harding, S., White, H., Doughty, R. N., Nunn, C., … on behalf of the ANZACS-QI Investigators. (2016). The All New Zealand Acute Coronary Syndrome Quality Improvement programme: Implementation, methodology and cohorts (ANZACS-QI 9). New Zealand Medical Journal, 129(1439), 23-36. Retrieved from https://www.nzma.org.nz/journal
Jones, G. T., Hill, B. G., Curtis, N., Kabir, T. D., Wong, L. E., Tilyard, M. W., Williams, M. J. A., & van Rij, A. M. (2016). Comparison of three targeted approaches to screening for abdominal aortic aneurysm based on cardiovascular risk. British Journal of Surgery, 103(9), 1139-1146. doi: 10.1002/bjs.10224
van 't Hof, F. N. G., Ruigrok, Y. M., Lee, C. H., Ripke, S., Anderson, G., de Andrade, M., … Jones, G. T., … van Rij, A. M., … Vascular Research Consortium of New Zealand, including Phillips, L. V., Hill, G. B., Williams, M. J. A., Thomson, I. A., Krysa, J., Wilkins, G. T., Merriman, T. R., Lewis, D. R., … de Bakker, P. I. W. (2016). Shared genetic risk factors of intracranial, abdominal, and thoracic aneurysms. Journal of the American Heart Association, 5(7), e002603. doi: 10.1161/jaha.115.002603
Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., … Williams, M. J. A., van Rij, A. M., Jones, G. T., … Stefansson, K. (2016). Variant ASGR1 associated with a reduced risk of coronary artery disease. New England Journal of Medicine, 374, 2131-2141. doi: 10.1056/NEJMoa1508419
Thomas, K. N., Cotter, J. D., Williams, M. J. A., & van Rij, A. M. (2016). Diagnosis, incidence, and clinical implications of perioperative myocardial injury in vascular surgery. Vascular & Endovascular Surgery, 50(4), 247-255. doi: 10.1177/1538574416637441
Jones, G. T., Phillips, V., Williams, M. J. A., van Rij, A. M., & Kabir, T. D. (2016). Two C-C family chemokines, eotaxin and RANTES, are novel independent plasma biomarkers for abdominal aortic aneurysm. Journal of the American Heart Association, 5(5), e002993. doi: 10.1161/jaha.115.002993
Thomas, K. N., Cotter, J. D., Williams, M. J. A., & van Rij, A. M. (2016). Repeated episodes of remote ischemic preconditioning for the prevention of myocardial injury in vascular surgery. Vascular & Endovascular Surgery, 50(3), 140-146. doi: 10.1177/1538574416639150
Williams, M. J. A., Harding, S. A., Devlin, G., Nunn, C., El-Jack, S., Scott, T., … on behalf of the ANZACS-QI Investigators, including Matsis, P., Smyth, D., Blake, J., Elliott, J., Lainchbury, J., Bridgman, P., Troughton, R., Wilkins, G., Green, B., Edmond, J., & Milburn, K. (2016). National variation in coronary angiography rates and timing after an acute coronary syndrome in New Zealand (ANZACS-QI 6). New Zealand Medical Journal, 129(1428), 65-77. Retrieved from https://www.nzma.org.nz/journal
Coffey, S., Cox, B., & Williams, M. J. A. (2016). Changing causes of heart valve disease mortality in New Zealand from 1988 to 2007. New Zealand Medical Journal, 129(1428), 55-64. Retrieved from https://www.nzma.org.nz/journal
Devlin, G., Williams, M., Elliott, J., White, H., French, J., Gamble, G., Matsis, P., Troughton, R., Richards, M., & Ellis, C. (2016). Management of non ST-elevation acute coronary syndrome patients in New Zealand: A longitudinal analysis: Results from the New Zealand Acute Coronary Syndrome national audits of 2002, 2007 and 2012. New Zealand Medical Journal, 129(1428), 9-15. Retrieved from https://www.nzma.org.nz/journal
Barr, P., Smyth, D., Harding, S. A., El-Jack, S., Williams, M. J. A., Devlin, G., … on behalf of the ANZACS-QI Investigators. (2016). Variation in arterial access for invasive coronary procedures in New Zealand: A national analysis (ANZACS-QI 5). Heart, Lung & Circulation, 25, 451-458. doi: 10.1016/j.hlc.2015.10.009
Rawal, S., Parshu Ram, T., Coffey, S., Williams, M. J. A., Saxena, P., Bunton, R. W., Galvin, I. F., & Katare, R. (2016). Differential expression pattern of cardiovascular microRNAs in the human type-2 diabetic heart with normal ejection fraction. International Journal of Cardiology, 202, 40-43. doi: 10.1016/j.ijcard.2015.08.161
Mandic, S., Stevens, E., Hodge, C., Brown, C., Walker, R., Body, D., … Nye, E. R., & Williams, M. J. A. (2016). Long-term effects of cardiac rehabilitation in elderly individuals with stable coronary artery disease. Disability & Rehabilitation, 38(9), 837-843. doi: 10.3109/09638288.2015.1061611
Conference Contribution - Poster Presentation (not in published proceedings)
Rawal, S., Munasinghe, P. E., Cameron, V., Manning, P., Williams, M. J. A., Jones, G. T., Bunton, R., Galvin, I., & Katare, R. (2016, August). microRNA-126 and microRNA-132 are the early modulators of diabetic microangiopathy in heart. Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Sharma, M., Redpath, G., Williams, M. J. A., & McCormick, S. P. A. (2016, August-September). Recycling of apolipoprotein(a) after PlgRKT-mediated endocytosis of lipoprotein(a). Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
2015
Journal - Research Article
Theodore, R. F., Broadbent, J., Nagin, D., Ambler, A., Hogan, S., Ramrakha, S., … Williams, M. J. A., Harrington, H., Moffitt, T. E., … Milne, B., & Poulton, R. (2015). Childhood to early-midlife systolic blood pressure trajectories: Early-life predictors, effect modifiers, and adult cardiovascular outcomes. Hypertension, 66, 1108-1115. doi: 10.1161/HYPERTENSIONAHA.115.05831
Coffey, S., Williams, M. J. A., Phillips, L. V., & Jones, G. T. (2015). Circulating microRNA profiling needs further refinement before clinical use in patients with aortic stenosis. Journal of the American Heart Association, 4(8), e002150. doi: 10.1161/jaha.115.002150
Bussey, C. T., Hughes, G., Saxena, P., Galvin, I. F., Bunton, R. W., Noye, M. K., Coffey, S., Williams, M. J. A., Baldi, J. C., Jones, P. P., & Lamberts, R. R. (2015). Chamber-specific changes in calcium-handling proteins in the type 2 diabetic human heart with preserved ejection fraction. International Journal of Cardiology, 193, 53-55. doi: 10.1016/j.ijcard.2015.05.053
Ellis, C., Hammett, C., Ranasinghe, I., French, J., Briffa, T., Devlin, G., Elliott, J., … Williams, M., Troughton, R., … on behalf of Bi-National Acute Coronary Syndromes (ACS) 'SNAPSHOT' Audit Group. (2015). Comparison of the management and in-hospital outcomes of acute coronary syndrome patients in Australia and New Zealand: Results from the binational SNAPSHOT acute coronary syndrome 2012 audit. Internal Medicine Journal, 45(5), 497-509. doi: 10.1111/imj.12739
Horwood, H., Williams, M. J. A., & Mandic, S. (2015). Examining motivations and barriers for attending maintenance community-based cardiac rehabilitation using the Health-Belief Model. Heart, Lung & Circulation, 24, 980-987. doi: 10.1016/j.hlc.2015.03.023
Sharma, M., Von Zychlinski-Kleffmann, A., Porteous, C. M., Jones, G. T., Williams, M. J. A., & McCormick, S. P. A. (2015). Lipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipids. Journal of Lipid Research, 56, 1318-1328. doi: 10.1194/jlr.M056150
Mandic, S., Body, D., Barclay, L., Walker, R., Nye, E. R., Grace, S. L., & Williams, M. J. A. (2015). Community-based cardiac rehabilitation maintenance programs: Use and effects. Heart, Lung & Circulation, 24, 710-718. doi: 10.1016/j.hlc.2015.01.014
Majeed, K., Hamer, A. W., White, S. C., Pegg, T. J., Wilkins, G. T., Williams, S. M., … Williams, M. J. A. (2015). Prevalence of abdominal aortic aneurysm in patients referred for transthoracic echocardiography. Internal Medicine Journal, 45(1), 32-39. doi: 10.1111/imj.12592
Journal - Professional & Other Non-Research Articles
Walters, D. L., Webster, M., Pasupati, S., Walton, A., Muller, D., Stewart, J., Williams, M., … Bannon, P. (2015). Position statement for the operator and institutional requirements for a transcatheter aortic valve implantation (TAVI) program. Heart, Lung & Circulation, 24, 219-223. doi: 10.1016/j.hlc.2014.09.009
Conference Contribution - Published proceedings: Abstract
Coffey, S., Prendergast, B. D., Williams, M. J. A., & Jones, G. T. (2015). Unsupervised network analysis of genome wide association study data identifies the epidermal growth factor receptor as the most connected hub in aortic valve calcification. European Heart Journal, 36(Suppl. 1), (pp. 1128-1129). doi: 10.1093/eurheartj/ehv401
Lamberts, R. R., Hughes, G., Bussey, C. T., Saxena, P., Galvin, I. F., Noye, M. K., Coffey, S., Williams, M. J. A., Baldi, J. C., Jones, P. P., on behalf of HeartOtago. (2015). Left ventricular calcium-handling proteins in the type 2 diabetic human heart with preserved ejection fraction. European Heart Journal, 36(Suppl. 1), (pp. 312-313). doi: 10.1093/eurheartj/ehv399
2014
Journal - Research Article
Jin, C., Phillips, L. V., Williams, M. J. A., van Rij, A. M., & Jones, G. T. (2014). Plasma heat shock protein 27 is associated with coronary artery disease, abdominal aortic aneurysm and peripheral artery disease. SpringerPlus, 3, 635. doi: 10.1186/2193-1801-3-635
Kader, T., Porteous, C. M., Williams, M. J. A., Gieseg, S. P., & McCormick, S. P. A. (2014). Ribose-cysteine increases glutathione-based antioxidant status and reduces LDL in human lipoprotein(a) mice. Atherosclerosis, 237(2), 725-733. doi: 10.1016/j.atherosclerosis.2014.10.101
Francois, M. E., Baldi, J. C., Manning, P. J., Lucas, S. J. E., Hawley, J. A., Williams, M. J. A., & Cotter, J. D. (2014). ‘Exercise snacks’ before meals: A novel strategy to improve glycaemic control in individuals with insulin resistance. Diabetologia, 57(7), 1437-1445. doi: 10.1007/s00125-014-3244-6
Coffey, S., Cox, B., & Williams, M. J. A. (2014). The prevalence, incidence, progression, and risks of aortic valve sclerosis: A systematic review and meta-analysis. JACC, 63(25), 2852-2861. doi: 10.1016/j.jacc.2014.04.018
von Zychilinski, A., Williams, M., McCormick, S., & Kleffmann, T. (2014). Absolute quantification of apolipoproteins and associated proteins on human plasma lipoproteins. Journal of Proteomics, 106, 181-190. doi: 10.1016/j.jprot.2014.04.030
Lamberts, R. R., Lingam, S. J., Wang, H.-Y., Bollen, I. A. E., Hughes, G., Galvin, I. F., Bunton, R. W., Bahn, A., Katare, R., Baldi, J. C., Williams, M. J. A., Saxena, P., Coffey, S., & Jones, P. P. (2014). Impaired relaxation despite upregulated calcium-handling protein atrial myocardium from type 2 diabetic patients with preserved ejection fraction. Cardiovascular Diabetology, 13, 72. doi: 10.1186/1475-2840-13-72
Moore, A., Shindikar, A., Fomison-Nurse, I., Riu, F., Munasinghe, P. E., Parshu Ram, T., Saxena, P., Coffey, S., Bunton, R. W., Galvin, I. F., Williams, M. J. A., … Katare, R. (2014). Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1. Cardiovascular Diabetology, 13, 68. doi: 10.1186/1475-2840-13-68
Coffey, S., Cox, B., & Williams, M. J. A. (2014). Lack of progress in valvular heart disease in the pre—transcatheter aortic valve replacement era: Increasing deaths and minimal change in mortality rate over the past three decades. American Heart Journal, 167(4), 562-567. doi: 10.1016/j.ahj.2013.12.030
Journal - Research Other
Kerr, A., & Williams, M. (2014). Infective endocarditis: Trends in the disease and how we study them. New Zealand Medical Journal, 127(1391). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Ellis, C., Gamble, G., Devlin, G., Elliott, J., Hamer, A., Matsis, P., Williams, M., Troughton, R., Mann, S., … Richards, A., … for the NZ Regional Cardiac Society ACS Audit Group, and the CSANZ 'SNAPSHOT' ACS Audit Group. (2014). Improved rates of secondary prevention medication following hospitalisation for an acute coronary syndrome (ACS) in New Zealand (NZ) : Results from the NZ ACS national audits of 2002, 2007 and 2012. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e23-e24). doi: 10.1016/j.hlc.2014.04.187
Elliott, J., Williams, M., Matsis, P., Gamble, G., Troughton, R., Hamer, A., … Mann, S., Richards, A., … for the NZ Regional Cardiac Society ACS Audit Group, and the CSANZ 'SNAPSHOT' ACS Audit Group. (2014). A decade of improvement in investigations received and treatments delivered to New Zealand (NZ) ST-elevation myocardial infarction (STEMI): Results from the NZACS national audits of 2002, 2007 and 2012. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e22-e23). doi: 10.1016/j.hlc.2014.04.185
Devlin, G., Hamer, A., Troughton, R., Gamble, G., Matsis, P., Williams, M., Elliott, J., Mann, S., Richards, A., … for the NZ Regional Cardiac Society ACS Audit Group, and the CSANZ 'SNAPSHOT' ACS Audit Group. (2014). Management of non ST-elevation acute coronary syndrome (NSTEACS) patients in New Zealand (NZ): A longitudinal analysis: Results from the NZACS national audits of 2002, 2007 and 2012. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e8-e9). doi: 10.1016/j.hlc.2014.04.148
Thomas, K., Cotter, J., Williams, M., & van Rij, A. (2014). Enhancing remote ischaemic preconditioning for protection in vascular surgery. ANZ Journal of Surgery, 84(Suppl. 1), (pp. 216). doi: 10.1111/ans.12633
Thomas, K., Cotter, J., Williams, M., & van Rij, A. (2014). Diagnosis, incidence and clinical implications of myocardial injury in vascular surgery. ANZ Journal of Surgery, 84(Suppl. 1), (pp. 215). doi: 10.1111/ans.12633
Drinkwater, B., van Rij, A., Williams, M., Curtis, N., Hill, G., & Jones, G. (2014). Aortic diameter shows a bimodal risk association for atherosclerotic arterial disease. New Zealand Medical Journal, 127(1395). Retrieved from http://www.nzma.org.nz/journal
Coffey, S., Williams, M. J. A., & Jones, G. T. (2014). MicroRNA profiling of diseased aortic valves. Cardiology, 128, (pp. 137-138). doi: 10.1159/000362180
Fomison-Nurse, I., Saxena, P., Coffey, S., Menon, A., Bunton, R., Galvin, I., Bahn, A., Williams, M., Cameron, V., & Katare, R. (2014). Diabetes causes the activation of the pro-ageing miRNA-34a in the human heart. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e24). doi: 10.1016/j.hlc.2014.04.188
Peebles, K., Baldi, J. C., Hoye, N., Murray, A., Sheat, C., Williams, M., Wilson, G., & Wilson, L. (2014). Heart rate variability indices are poor predictors of exercise capacity in healthy type 1 diabetes. FASEB Journal, 28(1, Suppl.), LB664. [Abstract]
Wilson, L., Coffey, S., Hoye, N., Murray, A., Lamberts, R., Williams, M., Wilkins, G., & Baldi, J. C. (2014). Impaired cardiac parasympathetic control in healthy young people with type 1 diabetes. FASEB Journal, 28(1, Suppl.), LB658. [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Williams, M. (2014, November). MicroRNA profiling of diseased aortic valves. Verbal presentation at the HeartOtago First Australasian Symposium: Bench to Bedside and Back: New Advances in Cardiovascular Research, Dunedin, New Zealand.
Williams, M. (2014, July). Endothelial function assessed with brachial artery flow mediated dilation. Verbal presentation at the Australasian Society for Ultrasound in Medicine (ASUM) New Zealand Branch Annual Scientific Meeting, Dunedin, New Zealand.
Other Research Output
Williams, M. (2014, June). Prevention and cure: The fight against cardiovascular disease. University of Otago, Dunedin, New Zealand. [Inaugural Professorial Lecture].
2013
Journal - Research Article
Ellis, C., Gamble, G., Devlin, G., Elliott, J., Hamer, A., Williams, M., Matsis, P., Troughton, R., … for the New Zealand Acute Coronary Syndromes (NZACS) 'SNAPSHOT' Audit Group. (2013). The management of acute coronary syndrome patients across New Zealand in 2012: Results of a third comprehensive nationwide audit and observations of current interventional care. New Zealand Medical Journal, 126(1387). Retrieved from http://www.nzma.org.nz/journal
Mandic, S., Hodge, C., Stevens, E., Walker, R., Nye, E. R., Body, D., Barclay, L., & Williams, M. J. A. (2013). Effects of community-based cardiac rehabilitation on body composition and physical function in individuals with stable coronary artery disease: 1.6-year followup. BioMed Research International, 2013, 903604. doi: 10.1155/2013/903604
Mandic, S., Walker, R., Stevens, E., Nye, E. R., Body, D., Barclay, L., & Williams, M. J. A. (2013). Estimating exercise capacity from walking tests in elderly individuals with stable coronary artery disease. Disability & Rehabilitation, 35(22), 1853-1858. doi: 10.3109/09638288.2012.759629
Jones, G. T., Bown, M. J., Gretarsdottir, S., Romaine, S. P. R., Helgadottir, A., Yu, G., … Jin, C., … Phillips, L. V., Williams, M. J. A., Topless, R., Merriman, T. R., … Lewis, D. R., … van Rij, A. M. (2013). A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm. Human Molecular Genetics, 22(14), 2941-2947. doi: 10.1093/hmg/ddt141
Tarr, G. P., Williams, M. J. A., Wilkins, G. T., Chen, V. H. T., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2013). Intra-individual changes of active matrix metalloproteinase-9 are associated with clinical in-stent restenosis of bare metal stents. Cardiology, 124(1), 28-35. doi: 10.1159/000345591
Sorrenson, B., Suetani, R. J., Williams, M. J. A., Bickley, V. M., George, P. M., Jones, G. T., & McCormick, S. P. A. (2013). Functional rescue of mutant ABCA1 proteins by sodium 4-phenylbutyrate. Journal of Lipid Research, 54, 55-62. doi: 10.1194/jlr.M027193
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2013). Plasma active matrix metalloproteinase 9 and indices of diastolic function in patients with preserved systolic function. International Journal of Cardiology, 167(4), 1242-1246. doi: 10.1016/j.ijcard.2012.03.147
Murrell, C. J., Cotter, J. D., Thomas, K. N., Lucas, S. J. E., Williams, M. J. A., & Ainslie, P. N. (2013). Cerebral blood flow and cerebrovascular reactivity at rest and during sub-maximal exercise: Effect of age and 12-week exercise training. Age, 35(3), 905-920. doi: 10.1007/s11357-012-9414-x
Journal - Research Other
Coffey, S., Williams, M. J. A., & Cox, B. (2013). Letter by Coffey et al regarding article, Estimating deaths from cardiovascular disease: A review of global methodologies of mortality measurement. Circulation, 128(6), e84. doi: 10.1161/CIRCULATIONAHA.113.002123
Tiong, I. S., Williams, M. J. A., & Perez, D. J. (2013). Nonbacterial thrombotic endocarditis with ST-elevation myocardial infarction treated with percutaneous coronary aspiration thrombectomy. Heart, Lung & Circulation, 22(5), 386-389. doi: 10.1016/j.hlc.2012.10.013
Journal - Professional & Other Non-Research Articles
ST-Elevation Mycocardial Infarction Guidelines Group, and the New Zealand Branch of the Cardiac Society of Australia and New Zealand, also Wong, C.-K., Smyth, D., Wilkins, G., Crozier, I., Elliott, J., Simmonds, M., Williams, M., & Matsis, P. (2013). ST-elevation myocardial infarction: New Zealand management guidelines, 2013. New Zealand Medical Journal, 126(1387). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Horwood, H., Williams, M., & Mandic, S. (2013). Attendance to community-based cardiac rehabilitation: Reasons and outcomes. Proceedings of the Sport and Exercise Science New Zealand (SESNZ) Annual Conference: Exercise Science for Health and Sport Performance. (pp. 47-48). Retrieved from http://www.sesnz.org.nz/Conference/
French, J., Hammett, C., Ellis, C., Devlin, G., Williams, M., Elliott, J., … Chew, D. (2013). STEMI care in Australia and New Zealand: Results from the Australia and New Zealand SNAPSHOT ACS. Heart, Lung & Circulation, 22(Suppl. 1), (pp. S49). doi: 10.1016/j.hlc.2013.05.117
Majeed, K., Hamer, A., White, S., Williams, S., Chen, Y., & Williams, M. (2013). Prevalence of abdominal aortic aneurysm in patients referred for transthoracic echocardiograms. Heart, Lung & Circulation, 22(Suppl. 1), (pp. S23). doi: 10.1016/j.hlc.2013.05.051
Lamberts, R., Lingam, S., Wang, S., Saxena, P., Galvin, I., Bunton, R., Williams, M., Coffey, S., Baldi, J., & Jones, P. (2013). Impaired functional relaxation despite upregulated calcium handling proteins in human diabetic myocardium. Heart, Lung & Circulation, 22(Suppl. 1), (pp. S57). doi: 10.1016/j.hlc.2013.05.137
Willoughby-Martin, K., Jones, G. T., Williams, M. J. A., Curtis, N., Hill, G. B., & van Rij, A. M. (2013). Severity of coronary artery disease is associated with prevalence of abdominal aortic aneurysm: Use of complex scoring systems for severity of coronary artery disease does not demonstrate a significant staged association with AAA prevalence. Heart, Lung & Circulation, 22(7), (pp. 592). doi: 10.1016/j.hlc.2013.04.104
Majeed, K., Hamer, A. W., White, S. C., Williams, S. M., Chen, Y. H., & Williams, M. J. A. (2013). Focussed screening for abdominal aortic aneursym in transthoracic echocardiogram subjects. Heart, Lung & Circulation, 22(7), (pp. 568). doi: 10.1016/j.hlc.2013.04.050
Conference Contribution - Verbal presentation and other Conference outputs
von Zychilinski, A., Williams, M., Kleffmann, T., & McCormick, S. (2013, August). What is really on our lipoproteins? Quantitative information about the protein makeup of the major lipoprotein classes. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Lingam, S. J., Wang, S. H. Y., Saxena, P., Galvin, I. F., Bunton, R. W., Williams, M. J. A., Coffey, S., Baldi, J. C., Jones, P. P., & Lamberts, R. R. (2013, August). Relaxation in human diabetic myocardium. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2012
Journal - Research Article
Nadarasa, K., & Williams, M. J. A. (2012). Single high oral dose amiodarone for cardioversion of recent onset atrial fibrillation. Heart, Lung & Circulation, 21(8), 444-448. doi: 10.1016/j.hlc.2012.03.015
Nadarasa, K., Robertson, M. C., Wong, C.-K., Green, B. K. W., Chen, V. H. T., Wilkins, G. T., & Williams, M. J. A. (2012). Rapid cycle change to predominantly radial access coronary angiography and percutaneous coronary intervention: Effect on vascular access site complications. Catheterization & Cardiovascular Interventions, 79(4), 589-594. doi: 10.1002/ccd.23120
Journal - Professional & Other Non-Research Articles
Non ST-Elevation Acute Coronary Syndrome Guidelines Group, and the New Zealand Branch of the Cardiac Society of Australia and New Zealand, including Wong, C.-K., Smyth, D., Wilkins, G., Crozier, I., Elliott, J., Simmonds, M., Williams, M., Matsis, P., Harding, S., & Mann, S. (2012). New Zealand 2012 guidelines for the management of non ST-elevation acute coronary syndromes [Special article]. New Zealand Medical Journal, 125(1357). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Lingam, S. J., Saxena, P., Coffey, S., Williams, M. J. A., Baldi, J. C., Lamberts, R. R., & Jones, P. P. (2012). Protein expression of SERCA2a and PLB in diabetes. Proceedings of the Oxygen Theme Meeting. (pp. 34). Dunedin, New Zealand: University of Otago. Retrieved from https://www.otago.ac.nz/research/otago051864.pdf
Lingam, S., Saxena, P., Coffey, S., Williams, M., Baldi, J., Lamberts, R., & Jones, P. (2012). Improved atrial relaxation in human type 2 diabetes mellitus. New Zealand Medical Journal, 125(1367). Retrieved from http://www.nzma.org.nz/journal
Wang, H.-Y., Baldi, J., Saxena, P., Coffey, S., Williams, M., & Lamberts, R. (2012). Reduced cardiac function and β-adrenergic receptor responsiveness in the isolated human diabetic myocardium. New Zealand Medical Journal, 125(1367). Retrieved from http://www.nzma.org.nz/journal
Coffey, S., Cox, B., & Williams, M. J. A. (2012). The increasing mortality of valvular heart disease. European Heart Journal, 33, (pp. 526). doi: 10.1093/eurheartj/ehs282
Mandic, S., Walker, R., Stevens, E., Brown, C., Giraldo Ocampo, D., Nye, E. R., … Barclay, L., & Williams, M. J. A. (2012). Correlates of exercise capacity in elderly individuals with and without coronary artery disease. Medicine & Science in Sports & Exercise, 44(5, Suppl. 2), (pp. 403). doi: 10.1249/01.mss.0000417529.22755.ed
Mandic, S., Walker, R., Stevens, E., McIlraith, B., Featherston, S., Nye, E. R., … Barclay, L., & Williams, M. J. A. (2012). Field versus laboratory tests: Exercise capacity estimates in elderly patients with coronary artery disease. Medicine & Science in Sports & Exercise, 44(5, Suppl. 2), (pp. 294). doi: 10.1249/01.mss.0000417529.22755.ed
Morley, T. D., Redpath, G. M. I., Kleffmann, T., von Zychilinski, A., Williams, M. J. A., & McCormick, S. P. A. (2012). Characterisation of the low density lipoprotein receptor binding properties of lipoproteins from a familial hypoalphalipoproteinemia subject. Proceedings of the Medical Sciences Congress (MedSci). (pp. 68). Retrieved from http://www.medscinz.co.nz/QRW2012%20MedSci%20Abstracts.pdf
Ellis, C. J., Gamble, G. D., Hamer, A., Devlin, G., Elliott, J. M., Matsis, P., Williams, M. J. A., Mann, S., … Richards, A. M., … For the Cardiac Society NZ ACS Audit Group. (2012). Is the mortality risk following an acute coronary syndrome (ACS) admission to a non-intervention centre related to access to cardiac angiography? Eighteen month follow-up of the 2002/2007 New Zealand (NZ) ACS audits. Heart, Lung & Circulation, 21(8), (pp. 488). doi: 10.1016/j.hlc.2012.03.034
Ellis, C. J., Gamble, G. D., Devlin, G., Hamer, A., Elliott, J. M., Matsis, P., Williams, M. J. A., Mann, S., … Richards, A. M., … For the Cardiac Society NZ ACS Audit Group. (2012). All cause mortality following an acute coronary syndrome (ACS) admission: Six year follow-up of the 2002 New Zealand (NZ) acute coronary syndromes audit. Heart, Lung & Circulation, 21(8), (pp. 487-488). doi: 10.1016/j.hlc.2012.03.033
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2012). Elevated plasma active matrix metalloproteinase 9 level is associated with increased diastolic dysfunction independent of hypertension and left ventricular hypertrophy in patients with coronary artery. Heart, Lung & Circulation, 21(8), (pp. 484). doi: 10.1016/j.hlc.2012.03.026
Coffey, S., Cox, B., & Williams, M. J. A. (2012). Valvular heart disease mortality in New Zealand 1988 to 2007. Heart, Lung & Circulation, 21(8), (pp. 484). doi: 10.1016/j.hlc.2012.03.027
Tie, C. L. H., Chen, V. H. T., Wilkins, G. T., Williams, M. J. A., Wong, C. K., Herbison, P., McKay, E. C., Vardi, L., & Middleton, A. (2012). Single versus multi-vessel PCI in STEMI patients with multivessel coronary artery disease in Dunedin public hospital. Heart, Lung & Circulation, 21(8), (pp. 517). doi: 10.1016/j.hlc.2012.03.101
Mandic, S., Williams, M. J. A., Stevens, E., Brown, C., Nye, E. R., Body, D., … Walker, R. (2012). Long-term effects of cardiac rehabilitation on exercise capacity and cardiovascular function in coronary artery disease. Heart, Lung & Circulation, 21(8), (pp. 499). doi: 10.1016/j.hlc.2012.03.059
Mandic, S., Hodge, C., Stevens, E., Horwood, H., Walker, R., Nye, E. R., … Williams, M. J. A. (2012). Effects of community-based cardiac rehabilitation on physical function and body composition in coronary artery disease: 1.5-year follow-up. Heart, Lung & Circulation, 21(8), (pp. 499-500). doi: 10.1016/j.hlc.2012.03.060
Conference Contribution - Poster Presentation (not in published proceedings)
Lingam, S. J., Saxena, P., Coffey, S., Williams, M. J. A., Baldi, J. C., Lamberts, R. R., & Jones, P. P. (2012, September). Improved atrial relaxation in human type 2 diabetes mellitus. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.
2011
Journal - Research Article
Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Pro-MMP-9/TIMP-1 ratio correlates poorly with a direct assessment of MMP-9 activity. Clinical Biochemistry, 44(17-18), 1480-1482. doi: 10.1016/j.clinbiochem.2011.09.019
Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Seasonal variation and stability of matrix metalloproteinase-9 activity and tissue inhibitor of matrix metalloproteinase-1 with storage at -80 oC. Clinical Biochemistry, 44(16), 1346-1348. doi: 10.1016/j.clinbiochem.2011.08.1139
von Zychlinski, A., Kleffmann, T., Williams, M. J. A., & McCormick, S. P. (2011). Proteomics of Lipoprotein(a) identifies a protein complement associated with response to wounding. Journal of Proteomics, 74, 2881-2891. doi: 10.1016/j.jprot.2011.07.008
Suetani, R. J., Sorrenson, B., Tyndall, J. D. A., Williams, M. J. A., & McCormick, S. P. A. (2011). Homology modeling and functional testing of an ABCA1 mutation causing Tangier disease. Atherosclerosis, 218(2), 404-410. doi: 10.1016/j.atherosclerosis.2011.06.019
Sorrenson, B., Suetani, R. J., Bickley, V. M., George, P. M., Williams, M. J. A., Scott, R. S., & McCormick, S. P. A. (2011). An ABCA1 truncation shows no dominant negative effect in a familial hypoalphalipoproteinemia pedigree with three ABCA1 mutations. Biochemical & Biophysical Research Communications, 409(3), 400-405. doi: 10.1016/j.bbrc.2011.05.006
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., & Ainslie, P. N. (2011). Syncope is unrelated to supine and postural hypotension following prolonged exercise. European Journal of Applied Physiology, 111(3), 469-476. doi: 10.1007/s00421-010-1671-8
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., & Ainslie, P. N. (2011). Cardiorespiratory and cerebrovascular responses to head-up tilt II: Influence of age, training status and acute exercise. Experimental Gerontology, 46(1), 1-8. doi: 10.1016/j.exger.2010.06.004
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Wilson, L., Thomas, K., Williams, M. J. A., & Ainslie, P. N. (2011). Cardiorespiratory and cerebrovascular responses to head-up tilt I: Influence of age and training status. Experimental Gerontology, 46(1), 9-17. doi: 10.1016/j.exger.2010.06.005
Journal - Research Other
Coffey, S., & Williams, M. (2011). Quetiapine-associated cardiomyopathy [Clinical correspondence]. New Zealand Medical Journal, 124(1337). Retrieved from http://journal.nzma.org.nz/journal/124-1337/4744/content.pdf
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2011). Plasma active matrix metalloproteinase 9 associated to diastolic dysfunction in patients with coronary artery disease [Letter]. International Journal of Cardiology, 147(2), 336-338. doi: 10.1016/j.ijcard.2010.12.093
Conference Contribution - Published proceedings: Abstract
Nadarasa, K., & Williams, M. (2011). Single high oral dose amiodarone for cardioversion of recent onset atrial fibrillation. Heart, Lung & Circulation, 20(Suppl. 2), (pp. S215-S216). doi: 10.1016/j.hlc.2011.05.530
Tarr, G. P., Williams, M. J. A., Wilkins, G. T., Chen, V. H. T., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). The development of bare metal in-stent restenosis is associated with intra-individual elevation of active MMP-9. Heart, Lung & Circulation, 20(6), (pp. 413). doi: 10.1016/j.hlc.2011.03.097
Conference Contribution - Poster Presentation (not in published proceedings)
Suetani, R., Sorrenson, B., Tyndall, J., Williams, M., & McCormick, S. (2011, September). Homology modelling and functional testing of ABCA1 mutations. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Nadarasa, K., & Williams, M. J. A. (2011, September). Single high oral dose amiodarone for cardioversion of recent onset atrial fibrillation. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2010
Journal - Research Article
Stewart, R. A. H., Kerr, A. J., Whalley, G. A., Legget, M. E., Zeng, I., Williams, M. J. A., Lainchbury, J., … Richards, M. A., … for the New Zealand Heart Valve Study Investigators. (2010). Left ventricular systolic and diastolic function assessed by tissue Doppler imaging and outcome in asymptomatic aortic stenosis. European Heart Journal, 31(18), 2216-2222. doi: 10.1093/eurheartj/ehq159
Ellis, C., Devlin, G., Elliott, J., Matsis, P., Williams, M., Gamble, G., … Richards, M., … for the New Zealand Acute Coronary Syndromes (NZACS) Audit Group. (2010). ACS patients in New Zealand experience significant delays to access cardiac investigations and revascularisation treatment especially when admitted to non-interventional centres: Results of the second comprehensive national audit of ACS patients. New Zealand Medical Journal, 123(1319). Retrieved from http://journal.nzma.org.nz/journal/123-1319/4237/content.pdf
Ellis, C., Gamble, G., Hamer, A., Williams, M., Matsis, P., Elliott, J., … Richards, M., … for the New Zealand Acute Coronary Syndromes (NZACS) Audit Group. (2010). Patients admitted with an acute coronary syndrome in New Zealand in 2007: Results of a second comprehensive nationwide audit and a comparison with the first audit from 2002. New Zealand Medical Journal, 123(1319). Retrieved from http://journal.nzma.org.nz/journal/123-1319/4235/content.pdf
Gretarsdottir, S., Baas, A. F., Thorleifsson, G., Holm, H., den Heijer, M., de Vries, J.-P. P. M., … van Rij, A. M., Williams, M. J. A., … Jones, G. T., … Stefansson, K. (2010). Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. Nature Genetics, 42(8), 692-697. doi: 10.1038/ng.622
Thomas, K. N., Galvin, S. D., Williams, M. J. A., Willie, C. K., & Ainslie, P. N. (2010). Identical pattern of cerebral hypoperfusion during different types of syncope. Journal of Human Hypertension, 24(7), 458-466. doi: 10.1038/jhh.2009.93
Sutherland, W. H. F., de Jong, S. A., Hessian, P. A., & Williams, M. J. A. (2010). Ingestion of native and thermally oxidized polyunsaturated fats acutely increases circulating numbers of endothelial microparticles. Metabolism, 59(3), 446-453. doi: 10.1016/j.metabol.2009.07.033
Conference Contribution - Published proceedings: Abstract
Mandic, S., Body, D., Nye, E., & Williams, M. (2010). Participation in community-based cardiac rehabilitation preserves physical function in elderly individuals. European Journal of Cardiovascular Prevention & Rehabilitation. 17(Suppl. 2), (pp. S23). [Abstract]
Chu, J., Jones, G., Tarr, G., Phillips, L., Wilkins, G., van Rij, A., & Williams, M. (2010). Elevated plasma active matrix metalloproteinase 9 level is associated with increased degree of diastolic dysfunction in patients with coronary artery disease. Heart, Lung & Circulation, 19(Suppl. 2), (pp. S216). doi: 10.1016/j.hlc.2010.06.524
Benoiton, L., Autagavaia, V., Pencheva, L., Perley, A., Hill, O., Song, N., Murphy, D., Sheriff, A., Allbon, D., … Williams, M. J. A., Wilkins, G. T., & Chen, V. H. T. (2010). Use of bivalirudin during primary percutaneous coronary intervention for acute ST elevation myocardial infarction. Heart, Lung & Circulation, 19(Suppl. 1), (pp. S4). doi: 10.1016/j.hlc.2010.04.008
Conference Contribution - Poster Presentation (not in published proceedings)
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2010, August). Elevated plasma active matrix metalloproteinase 9 level is associated with increased degree of diastolic dysfunction in patients with coronary artery disease. Poster session presented at the Cardiac Society of Australia and New Zealand Annual Scientific Meeting, Adelaide, Australia.
Tarr, G., Phillips, L. V., Wilkins, G. T., van Rij, A. M., Williams, M. J. A., & Jones, G. T. (2010, September). The development of in-stent restenosis is associated with intra-individual elevation of active MMP-9. Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand.
2009
Journal - Research Article
Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2009). Active matrix metalloproteinases 3 and 9 are independently associated with coronary artery in-stent restenosis. Atherosclerosis, 207(2), 603-607. doi: 10.1016/j.atherosclerosis.2009.05.036
Murrell, C. J., Cotter, J. D., George, K. P., Shave, R., Wilson, L. C., Thomas, K. N., Williams, M. J. A., … Ainslie, P. N. (2009). Influence of age on syncope following prolonged exercise: Differential responses but similar orthostatic intolerance. Journal of Physiology, 587(24), 5959-5969. doi: 10.1113/jphysiol.2009.179549
Thomas, K. N., Cotter, J. D., Galvin, S. D., Williams, M. J. A., Willie, C. K., & Ainslie, P. N. (2009). Initial orthostatic hypotension is unrelated to orthostatic tolerance in healthy young subjects. Journal of Applied Physiology, 107(2), 506-517. doi: 10.1152/japplphysiol.91650.2008
Gudbjartsson, D. F., Bjornsdottir, U. S., Halapi, E., Helgadottir, A., Sulem, P., Jonsdottir, G. M., … Williams, M. J. A., van Rij, A. M., Jones, G. T., … Stefansson, K. (2009). Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nature Genetics, 41(3), 342-347. doi: 10.1038/ng.323
Conference Contribution - Published proceedings: Abstract
Murrell, C., Cotter, J. D., George, K., Shave, R., Oxborough, D., Wilson, L. C., Thomas, K., Williams, M. J. A., & Ainslie, P. N. (2009). Older age has no effect on orthostatic tolerance following prolonged exercise. Medicine & Science in Sports & Exercise, 41(5, Suppl. 1), (pp. 7). doi: 10.1249/01.MSS.0000354584.40021.49
Brace, R., Williams, M., Sviridov, D., Mukhamedova, N., & McCormick, S. (2009). Influence of ABCA1 promoter haplotypes on a novel R1068H mutation. Atherosclerosis Supplements. 10(2), (pp. e452). [Abstract]
Sorrenson, B., Jones, G. T., Williams, M. J., Bickley, V. M., Scott, R. S., George, P. M., & McCormick, S. P. A. (2009). Functional studies of novel ABCA1 mutations associated with low HDL-cholesterol levels. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Brace, R. J., Williams, M. J., Tyndall, J. D. A., Sviridov, D., Mukhamedova, N., Albrecht, C., & McCormick, S. P. A. (2009). Characterisation of a novel Tangier disease ABCA1 protein. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Kwon, H. J., Chen, V. H. T., Wilkins, G. T., & Williams, M. J. A. (2009). Comparison of primary percutaneous coronary intervention with thrombolytic therapy for ST elevation myocardial infarction in Dunedin Hospital 2007. Heart, Lung & Circulation, 18(Suppl. 3), (pp. S206). doi: 10.1016/j.hlc.2009.05.511
Conference Contribution - Poster Presentation (not in published proceedings)
Sorrenson, B., Jones, G. T., Williams, M. J., Bickley, V. M., Scott, R. S., George, P. M., & McCormick, S. P. A. (2009, September). Functional studies of novel ABCA1 mutations associated with low HDL-cholesterol levels. Poster session presented at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand.
2008
Journal - Research Article
Manning, P. J., Sutherland, W. H. F., McGrath, M. M., de Jong, S. A., Walker, R. J., & Williams, M. J. A. (2008). Postprandial cytokine concentrations and meal composition in obese and lean women. Obesity, 16(9), 2046-2052. doi: 10.1038/oby.2008.334
Slatter, T. L., Jones, G. T., Williams, M. J. A., van Rij, A. M., & McCormick, S. P. A. (2008). Novel rare mutations and promoter haplotypes in ABCA1 contribute to low-HDL-C levels. Clinical Genetics, 73, 179-184. doi: 10.1111/j.1399-0004.2007.00940.x
Peng, T., Ainslie, P. N., Cotter, J. D., Murrell, C., Thomas, K., Williams, M. J. A., … Payne, S. J. (2008). The effects of age on the spontaneous low-frequency oscillations in cerebral and systemic cardiovascular dynamics. Physiological Measurement, 29, 1055-1069.
Ainslie, P. N., Cotter, J. D., George, K. P., Lucas, S., Murrell, C., Shave, R., Thomas, K. N., Williams, M. J. A., & Atkinson, G. (2008). Elevation in cerebral blood flow velocity with aerobic fitness throughout healthy human ageing. Journal of Physiology, 586(16), 4005-4010. doi: 10.1113/jphysiol.2008.158279
Jones, G. T., van Rij, A. M., Hill, G. B., Wilkins, G. T., & Williams, M. J. A. (2008). Common carotid intimal-medial thickness is associated with coronary in-stent restenosis. Journal for Vascular Ultrasound, 32(3), 129-132.
Conference Contribution - Published proceedings: Abstract
Manning, P. J., Sutherland, W. H. F., McGrath, M., de Jong, S. A., Walker, R. J., & Williams, M. J. A. (2008). The effect of meals rich in different types of fat and carbohydrate on plasma inflammatory cytokine concentrations in obese and lean women. Diabetes Research and Clinical Practice. 79(Suppl. 1), (pp. S16). [Abstract]
Stewart, R. A. H., Kerr, A., Legget, M. E., Richards, M., Whalley, G., Friedlander, D., … Williams, M., Simmonds, M., … Lainchbury, J., … White, H. D. (2008). N-terminal pro-B-type natriuretic peptide in aortic stenosis: Results from the NZ Heart Valve Study. Heart, Lung & Circulation, 17(Suppl. 2), (pp. S9-S10). doi: 10.1016/j.hlc.2008.03.019
Conference Contribution - Poster Presentation (not in published proceedings)
Brace, R. J., Williams, M. J., Sviridov, D., Mukhamedova, N., & McCormick, S. P. A. (2008, November-December). Influence of ABCA1 promoter SNPS on promoter activity in cultured cells. Poster session presented at the New Zealand Institute of Chemistry, New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Biologists Combined Conference, Dunedin, New Zealand.
Jones, G., Tarr, G., Phillips, V., Williams, M., Wilkins, G., & van Rij, A. (2008, June). Active forms of matrix metalloproteinases are independent predictors of in-stent restenosis. Poster session presented at the 15th International Vascular Biology Meeting, Sydney, Australia.
2007
Journal - Research Article
Tie, S., Wong, C.-K., Yap, J., Wilkins, G., Williams, M., & Kay, P. (2007). Timing of thrombotic events in patients receiving 2 weeks of clopidogrel therapy post bare metal coronary artery stenting: A New Zealand retrospective study. New Zealand Medical Journal, 120(1255). Retrieved from http://journal.nzma.org.nz/journal/120-1255/2553/content.pdf
Sutherland, W. H., Williams, M. J., & de Jong, S. A. (2007). Plasma protein lipofuscin-like fluorophores in men with coronary artery disease treated with statins. Archives of Medical Research, 38, 757-763.
Sutherland, W. H. F., Williams, M. J. A., de Jong, S. A., & McCormick, M. P. (2007). Ingestion of moderately thermally oxidized polyunsaturated fat decreases serum resistance to oxidation in men with coronary artery disease. Nutrition Research, 27, 265-272. doi: 10.1016/j.nutres.2006.12.014
Hancox, R. J., Poulton, R., Greene, J. M., Filsell, S., McLachlan, C. R., Rasmussen, F., Taylor, D. R., Williams, M. J. A., Williamson, A., & Sears, M. R. (2007). Systemic inflammation and lung function in young adults. Thorax, 62, 1064-1068.
Ainslie, P. N., Murrell, C., Peebles, K., Swart, M., Skinner, M. A., Williams, M. J. A., & Taylor, D. R. (2007). Early morning impairment in cerebral autoregulation and cerebrovascular CO2 reactivity in healthy humans: Relation to endothelial function. Experimental Physiology, 92(4), 769-777.
Jones, G. T., van Rij, A. M., Cole, J., Williams, M. J. A., Bateman, E. H., Marcovina, S. M., Deng, M., & McCormick, S. P. A. (2007). Plasma lipoprotein(a) indicates risk for 4 distinct forms of vascular disease. Clinical Chemistry, 53(4), 679-685.
Journal - Research Other
Williams, M. (2007). Percutaneous coronary intervention in New Zealand [Editorial]. New Zealand Medical Journal, 120(1248). Retrieved from http://journal.nzma.org.nz/journal/120-1248/2398/content.pdf
Conference Contribution - Published proceedings: Abstract
Tarr, G., Jones, G. T., Chu, J., Wilkins, G., & Williams, M. J. A. (2007). Matrix metalloproteinases are independent predictors of in-stent restenosis. Heart, Lung & Circulation, 16(Suppl. 2), (pp. S171). doi: 10.1016/j.hlc.2007.06.426
Parker, S., Forward, K., Jones, G., Williams, M., Cole, J., van Rij, A., & McCormick, S. (2007). Screening for a new 'null' apo(a) allele. New Zealand Medical Journal, 120(1255). Retrieved from http://journal.nzma.org.nz/journal/120-1255/2574/content.pdf
Tarr, G., Jones, G. T., Chu, J., Wilkins, G., & Williams, M. J. A. (2007). Matrix metalloproteinases are independent predictors of in-stent restenosis. New Zealand Medical Journal, 120(1255). Retrieved from http://journal.nzma.org.nz/journal/120-1255/2574/content.pdf
Murrell, C. J., Cotter, J. D., George, K., Shave, R., Oxborough, D., Wilson, L., Thomas, K., Williams, M. J. A., & Ainslie, P. N. (2007). Effect of age on orthostatic tolerance following prolonged exercise. Proceedings of the New Zealand Sports Medicine+Science Conference. (pp. 70). Dunedin, New Zealand: Sports Medicine New Zealand. [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Jones, G., van Rij, A., McCormick, S., Deng, M., & Williams, M. (2007, August). Lipoprotein(a) is an independent predictor of atherothromobotic vascular disease. Verbal presentation at the Vascular Conference, Melbourne, Australia.
2006
Journal - Research Article
Jones, G. T., Kay, I. P., Chu, J. W. S., Wilkins, G. T., Phillips, L. V., McCormick, M., van Rij, A. M., & Williams, M. J. A. (2006). Elevated plasma active matrix metalloproteinase-9 level is associated with coronary artery in-stent restenosis. Arteriosclerosis, Thrombosis, & Vascular Biology, 26, e121-e125.
Tang, E. W., Wong, C.-K., Restieaux, N. J., Herbison, P., Williams, M. J. A., Kay, P., & Wilkins, G. T. (2006). Clinical outcome of older patients with acute coronary syndrome over the last three decades. Age & Ageing, 35, 280-285.
Williams, M. J. A., Williams, S. M., & Poulton, R. (2006). Breast feeding is related to C reactive protein concentration in adult women. Journal of Epidemiology & Community Health, 60, 146-148.
Slatter, T. L., Williams, M. J. A., Frikke-Schmidt, R., Tybjærg-Hansen, A., Morison, I. M., & McCormick, S. P. A. (2006). Promoter haplotype of a new ABCA1 mutant influences expression of familial hypoalphalipoproteinemia. Atherosclerosis, 187, 393-400.
Conference Contribution - Published proceedings: Abstract
Tie, S. L. J., Wong, C.-K., Yap, J., Wilkins, G. T., Williams, M. J., & Kay, I. P. (2006). Are there rebound thrombotic events if only two weeks of clopidogrel therapy was given post bare metal coronary artery stenting? Heart, Lung & Circulation, 15(Suppl. 1), (pp. S148). doi: 10.1016/j.hlc.2006.05.003
Ellis, C. J., Gamble, G. D., Elliott, J. M., Devlin, G., Matsis, P., Williams, M., Mann, S., … Richards, A. M., … for the NZ ACS Audit Group. (2006). The influence of gender and age on service provision for acute coronary syndrome patients in New Zealand. Heart, Lung & Circulation, 15(3), (pp. 222). doi: 10.1016/j.hlc.2006.03.008
Ellis, C. J., Gamble, G. D., Williams, M., Devlin, G., Matsis, P., Elliott, J. M., Mann, S., … Richards, A. M., … for the NZACS Audit Group. (2006). Service provision to Maori compared to non-Maori acute coronary syndrome patients in New Zealand. Heart, Lung & Circulation, 15(3), (pp. 223). doi: 10.1016/j.hlc.2006.03.008
van Rij, A. M., Jones, G. T., Phillips, L. V., Rossaak, J. I., Williams, M. J. A., & McCormick, S. P. A. (2006). Abdominal aortic aneurysm disease is not just atherosclerosis: Genetic and phenotypic comparisons. ANZ Journal of Surgery, 76(Suppl. 1), (pp. A95). doi: 10.1111/j.1445-2197.2006.03822.x
Hancox, R. J., Poulton, R., Williams, M., Caspi, A., Taylor, D. R., McLachlan, C. R., Williamson, A. J., Filsell, S. J., & Sears, M. R. (2006). Systemic inflammation and lung function in young adults. European Respiratory Journal, 28(Suppl. 50), (pp. 593s). [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Jones, G. T., Phillips, L. V., Williams, M. J. A., & van Rij, A. M. (2006, March). Renin-angiotensin system genotypes are associated with abdominal aortic aneurysm. Poster session presented at the Heart Foundation: Conference and Scientific Meeting, Sydney, Australia.
Conference Contribution - Verbal presentation and other Conference outputs
Jones, G. T., van Rij, A. M., Phillips, L. V., Deng, M., Williams, M. J. A., Kay, P., … Chu, J., & MacCormack, S. P. (2006, June). Differential genotypic and phenotypic risk factors for abdominal aortic aneurysm compared to peripheral vascular, carotid and coronary artery disease. Verbal presentation at the XXII World Congress of the International Union of Angiology, Lisboa, Portugal.
2005
Journal - Research Article
Tang, E. W., Wong, C.-K., Wilkins, G., Herbison, P., Williams, M., Kay, P., & Restieaux, N. (2005). Use of evidence-based management for acute coronary syndrome. New Zealand Medical Journal, 118(1223). Retrieved from http://journal.nzma.org.nz/journal/118-1223/1678/content.pdf
Williams, M. J., Sutherland, W. H., McCormick, M. P., Yeoman, D. J., & de Jong, S. A. (2005). Aged garlic extract improves endothelial function in men with coronary artery disease. Phytotherapy Research, 19(4), 314-319.
Williams, M. J. A., Milne, B. J., Hancox, R. J., & Poulton, R. (2005). C-reactive protein and cardiorespiratory fitness in young adults. European Journal of Cardiovascular Prevention & Rehabilitation, 12(3), 216-220.
Conference Contribution - Published proceedings: Abstract
Williams, M. J. A., Williams, S. M., & Poulton, R. (2005). Infant breast-feeding influences C-reactive protein concentration in adult women. Heart, Lung & Circulation, 14(2), (pp. 155-156). doi: 10.1016/j.hlc.2005.03.001
Tie, S., Wong, C.-K., Yap, J., Wilkins, G. T., Williams, M. J., & Kay, I. P. (2005). Is two weeks of clopidogrel therapy sufficient post coronary stenting? Heart, Lung & Circulation, 14(2), (pp. 154). doi: 10.1016/j.hlc.2005.03.001
Tie, S., Wong, C.-K., Yap, J., Williams, M. J., Kay, I. P., & Wilkins, G. T. (2005). Outcome in the first 70 days post-percutaneous coronary intervention in 1000 consecutive patients in Dunedin Hospital. Heart, Lung & Circulation, 14(2), (pp. 139). doi: 10.1016/j.hlc.2005.03.001
Tang, E. W., Wong, C.-K., Restieaux, N., Williams, M., Kay, I., & Wilkins, G. (2005). Changing demography and outcome of patients with acute coronary syndrome (ACS) admitted into Dunedin Coronary Care Unit (CCU) in the past 3 decades. Heart, Lung & Circulation, 14(1, Suppl.), (pp. S70). doi: 10.1016/j.hlc.2005.04.007
Williams, M. J. A., Jones, G. T., Phillips, L. V., & van Rij, A. M. (2005). Variations in inflammatory genetic polymorphisms are associated with susceptibility to coronary artery disease. Heart, Lung & Circulation, 14(1, Suppl.), (pp. S49). doi: 10.1016/j.hlc.2005.04.007
Chu, J. W., Jones, G., Kay, I. P., Williams, M. J., Wilkins, G. T., Phillips, V., McCormick, M., & van Rij, A. M. (2005). Plasma matrix metalloproteinase-9 level is a predictor for restenosis after coronary artery stenting. JACC, 45(Suppl. 1), (pp. 76A). [Abstract]
2004
Chapter in Book - Research
Williams, M. J. A. (2004). The importance of echocardiography to the interventionalist. In I. P. Kay, M. Sabaté & M. A. Costa (Eds.), Cardiac catheterization and percutaneous interventions. (pp. 407-416). London: Taylor & Francis.
Journal - Research Article
Williams, M. J. A., Williams, S. M., Milne, B. J., Hancox, R. J., & Poulton, R. (2004). Association between C-reactive protein, metabolic cardiovascular risk factors, obesity and oral contraceptive use in young adults. International Journal of Obesity, 28, 998-1003.
Chu, J., Wilkins, G., & Williams, M. (2004). Review of 65 cases of infective endocarditis in Dunedin Public Hospital. New Zealand Medical Journal, 117(1200). Retrieved from http://journal.nzma.org.nz/journal/117-1200/1021/content.pdf
Ellis, C., Devlin, G., Matsis, P., Elliott, J., Williams, M., Gamble, G., Mann, S., … for the New Zealand Acute Coronary Syndromes (NZACS) Audit Group. (2004). Acute coronary syndrome patients in New Zealand receive less invasive management when admitted to hospitals without invasive facilities. New Zealand Medical Journal, 117(1197). Retrieved from http://journal.nzma.org.nz/journal/117-1197/954/content.pdf
Ellis, C., Gamble, G., French, J., Devlin, G., Matsis, P., Elliott, J., Mann, S., Williams, M., … for the New Zealand Acute Coronary Syndromes (NZACS) Audit Group. (2004). Management of patients admitted with an acute coronary syndrome in New Zealand: Results of a comprehensive nationwide audit. New Zealand Medical Journal, 117(1197). Retrieved from http://journal.nzma.org.nz/journal/117-1197/953/content.pdf
Whelan, A. P., Sutherland, W. H. F., McCormick, M. P., Yeoman, D. J., de Jong, S. A., & Williams, M. J. A. (2004). Effects of white and red wine on endothelial function in subjects with coronary artery disease. Internal Medicine Journal, 34, 224-228.
Williams, M. J. A., Sutherland, W. H. F., Whelan, A. P., McCormick, M. P., & de Jong, S. A. (2004). Acute effect of drinking red and white wines on circulating levels of inflammation-sensitive molecules in men with coronary artery disease. Metabolism, 53(3), 318-323.
Conference Contribution - Published proceedings: Abstract
Williams, M. J. A., Jones, G. T., Chu, J. W. S., Kay, I. P., Phillips, V., McCormick, M. P., Wilkins, G. T., & van Rij, A. M. (2004). Plasma matrix metalloproteinase-9 level is a predictor for restenosis after coronary artery stenting. Heart, Lung & Circulation, 13(Suppl. 2), (pp. S46-S47). doi: 10.1016/j.hlc.2004.05.001
Ellis, C. J., French, J. K., Devlin, G., Elliott, J. M., Matsis, P., Williams, M., Mann, S., … for the NZACS Audit Group. (2004). Marked variation in troponin assays and use in New Zealand. Heart, Lung & Circulation, 13(2), (pp. 223-224). doi: 10.1016/j.hlc.2004.04.002
Williams, M. J. A., Williams, S. M., Milne, B. J., Hancox, R. J., & Poulton, R. (2004). Oral contraceptive use in healthy young women is associated with elevated C-reactive protein. Heart, Lung & Circulation, 13(Suppl. ), (pp. S43). doi: 10.1016/j.hlc.2004.02.001
Williams, M. J. A., Milne, B. J., Hancox, R. J., & Poulton, R. (2004). Physical fitness and C-reactive protein levels in young men and women. Heart, Lung & Circulation, 13(Suppl.), (pp. S68). doi: 10.1016/j.hlc.2004.02.001
Williams, M. J. A., Sutherland, W. H. F., McCormick, M. P., Yeoman, D. J., & de Jong, S. A. (2004). The effect of aged garlic extract on oxidised LDL, inflammatory markers, and endothelial function in men with coronary artery disease. Heart, Lung & Circulation, 13(Suppl.), (pp. S52). doi: 10.1016/j.hlc.2004.02.001
Williams, M. J., Milne, B. J., Hancox, R. J., & Poulton, R. (2004). Association between cardiorespiratory fitness and C-reactive protein in young adults. JACC, 43(5; Suppl. 2), (pp. 455A). doi: 10.1016/S0735-1097(04)91920-1
Conference Contribution - Poster Presentation (not in published proceedings)
Slatter, T. L., Williams, M. J., Frikke-Schmidt, R., Tybjærg-Hansen, A., Morison, I., & McCormick, S. P. A. (2004, December). ABCA1 promoter haplotypes influence HDL levels in a novel case of Tangier disease. Poster session presented at the 14th Annual Queenstown Molecular Biology Meeting in conjunction with the New Zealand Society for Biochemical and Molecular Biology Conference, Queenstown, New Zealand.
2003
Journal - Research Article
Pfeffer, M. A., McMurray, J. J. V., Velazquez, E. J., Rouleau, J.-L., Køber, L., Maggioni, A. P., … Wilkins, G., Williams, M., & Wong, C. K. (2003). Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. New England Journal of Medicine, 349(20), 1893-1906. doi: 10.1056/NEJMoa032292
Cohn, J. N., Pfeffer, M. A., Rouleau, J., Sharpe, N., Swedberg, K., Straub, M., … for the MOXCON Investigators, including Williams, M. (2003). Adverse mortality effect of central sympathetic inhibition with sustained-release moxonidine in patients with heart failure (MOXCON). European Journal of Heart Failure, 5, 659-667. doi: 10.1016/S1388-9842(03)00163-6
Journal - Research Other
Williams, M. (2003). Risk assessment and management of cardiovascular disease in New Zealand [Editorial]. New Zealand Medical Journal, 116(1185). Retrieved from http://journal.nzma.org.nz/journal/116-1185/661/content.pdf
Williams, M. J. A., Poulton, R., & Williams, S. M. (2003). Ferritin and cardiovascular risk [Letter to the editor]. Atherosclerosis, 167, 171.
Conference Contribution - Published proceedings: Abstract
Williams, M. J. A., Milne, B. J., Hancox, R. J., & Poulton, R. (2003). C-reactive protein is related to physical fitness in young, healthy women. New Zealand Medical Journal, 116(1185). Retrieved from http://journal.nzma.org.nz/journal/116-1185/669/content.pdf
Williams, M. J. A., Poulton, R., & Williams, S. M. (2003). Obesity is associated with systemic inflammation independent of metabolic cardiac risk factors in healthy young adults. JACC, 41(6, Suppl. 1), (pp. 234A-235A). doi: 10.1016/S0735-1097(03)81674-1
Chu, J. W. S., Wilkins, G. T., & Williams, M. J. A. (2003). Infective endocarditis in Dunedin Public Hospital: A review of 65 episodes. New Zealand Medical Journal, 116(1185). Retrieved from http://journal.nzma.org.nz/journal/116-1185/669/content.pdf
Ellis, C. J., Gamble, G. D., French, J. K., Devlin, G., Elliott, J. M., Mann, S., Matsis, P., Williams, M., & White, H. D. (2003). Acute coronary syndrome (ACS) patients in New Zealand receive less invasive management if admitted to hospitals without invasive facilities. New Zealand Medical Journal, 116(1185). Retrieved from http://journal.nzma.org.nz/journal/116-1185/669/content.pdf
Ellis, C. J., Gamble, G. D., French, J. K., Devlin, G., Elliott, J. M., Mann, S., Matsis, P., Williams, M., & White, H. D. (2003). Inadequate service provision for the management of patients admitted with an acute coronary syndrome in New Zealand: A comprehensive nationwide audit of practice in 2002. New Zealand Medical Journal, 116(1185). Retrieved from http://journal.nzma.org.nz/journal/116-1185/669/content.pdf
2002
Journal - Research Article
Pacific Study Group, including Williams, M., & Mann, S. (2002). Effects of the vasopeptidase inhibitor, omapatrilat, in 723 patients with coronary heart disease. Journal of the Renin-Angiotensin-Aldosterone System, 3(4), 270-276.
Sutherland, W. H. F., De Jong, S. A., Walker, R. J., Williams, M. J. A., Skeaff, C. M., Duncan, A., & Harper, M. J. (2002). Effect of meals rich in heated olive and safflower oils on oxidation of postprandial serum in healthy men. Atherosclerosis, 160, 195-203.
Williams, M. J. A., Poulton, R., & Williams, S. M. (2002). Relationship of serum ferritin with cardiovascular risk factors and inflammation in young men and women. Atherosclerosis, 165, 179-184.
Aebli, N., Krebs, J., Davis, G., Walton, M. H., Williams, M. J. A., & Theis, J.-C. (2002). Fat embolism and acute hypotension during vertebroplasty: An experimental study in sheep. Spine, 27(5), 460-466.
Journal - Professional & Other Non-Research Articles
Williams, M. J. A., & Stewart, R. A. (2002). Inflammation, atherosclerosis and predicting cardiovascular risk. New Zealand Medical Journal, 115(1163), U196. Retrieved from http://www.nzma.org.nz/journal/115-1163/196
Conference Contribution - Published proceedings: Abstract
Ellis, C. J., French, J. K., Devlin, G. P., Matsis, P., Elliott, J. M., Williams, M. J. A., … White, H. D. (2002). Patients admitted with an acute coronary syndrome in New Zealand: An audit of practice in 2002. NZ Regional Scientific Meeting of Cardiac Society of Australia and New Zealand, the Internal Medicine Society of Australia and New Zealand and the Royal Australasian College of Physicians. 115, (pp. 64). New Zealand Medical Journal. [Abstract]
Williams, M. J. A., Poulton, R., & Williams, S. M. (2002). Ferritin is related to cardiovascular risk factors in young men and women. NZ Regional Scientific Meeting of Cardiac Society of Australia and New Zealand, the Internal Medicine Society of Australia and New Zealand and the Royal Australasian College of Physicians. 115, (pp. U194). New Zealand Medical Journal. Retrieved from http://www.nzma.org.nz/journal/115-162/194
Williams, M. J. A., Poulton, R., & Williams, S. M. (2002). Relationship between C-reactive protein and obesity in healthy young adults. NZ Regional Scientific Meeting of Cardiac Society of Australia & New Zealand, the Internal Medicine Society of Australia and New Zealand, and the Royal Australasian College of Physicians. 115, (pp. 51). New Zealand Medical Journal. [Abstract]
Aebli, N., Krebs, J., Davis, G., Walton, M. H., Williams, M. J. A., & Theis, J.-C. (2002). Fat embolism and acute hypotension during vertebroplasty in sheep. Journal of Bone and Joint Surgery (BR). 84B(Suppl. III), (pp. 287). [Abstract]
2001
Journal - Research Article
Williams, M. J. A., Sutherland, W. H. F., McCormick, M., de Jong, S. A., McDonald, J. R., & Walker, R. J. (2001). Vitamin C improves endothelial dysfunction in renal allograft recipients. Nephrology Dialysis Transplantation, 16, 1251-1255.
Williams, M. J. A., & Walker, R. J. (2001). When is an ANCA an anchor? Internal Medicine Journal, 31(5), 308-311.
Whelan, A. P., & Williams, M. J. A. (2001). Spontaneous intramural aortic haematoma. New Zealand Medical Journal, 114, 38-41.
Williams, M. J. A., Sutherland, W. H. F., McCormick, M., Yeoman, D., de Jong, S. A., & Walker, R. J. (2001). Normal endothelial function after meals rich in olive or safflower oil previously used for deep frying. Nutrition, Metabolism & Cardiovascular Diseases, 11, 147-152.
Kerr, A. J., Williams, M. J. A., & Stewart, R. A. H. (2001). Ventricular rate and beat to beat variation of stroke volume in atrial fibrillation. American Journal of Cardiology, 87(9), 1116-1119.
Conference Contribution - Published proceedings: Abstract
Aebli, N., Krebs, J., Davis, G., Walton, M., Williams, M. J. A., & Theis, J.-C. (2001). Fat embolism and acute hypotension during vertebroplasty in sheep. Journal of Bone and Joint Surgery (Br). 83B(Suppl. IV), (pp. 442). [Abstract]
Whelan, A. P., Wilkins, G. T., McCormick, M., & Williams, M. J. A. (2001). Target lesion revascularisation after stenting in small coronary vessels. Heart, Lung & Circulation, 10(3), (pp. A134). doi: 10.1046/j.1444-2892.2001.00002.x
Whelan, A. P., Sutherland, W. H. F., McCormick, M., Yeoman, D., de Jong, S. A., & Williams, M. J. A. (2001). Wine improves endothelial dysfunction in men with coronary artery disease. Heart, Lung & Circulation, 10(3), (pp. A109). doi: 10.1046/j.1444-2892.2001.00002.x
Conference Contribution - Verbal presentation and other Conference outputs
Aebli, N., Krebs, J., Davis, G., Walton, M., Williams, M. J. A., & Theis, J.-C. (2001, November). Cardiovascular changes during fat embolism caused by vertebroplasty in sheep. Verbal presentation at the Interpore Cross/AOM Vertebroplasty Workshop, Sydney.
Theis, J.-C., Krebs, J., Davis, G., Walton, M., Aebli, N., & Williams, M. J. A. (2001, June). Fat embolism during vertebroplasty in sheep. Verbal presentation at the StrykerRs ″Controversies and Challenges in Spine Surgery″, Queensland.
Aebli, N., Krebs, J., Davis, G., Walton, M., Williams, M. J. A., & Theis, J.-C. (2001, October). Fat embolism and acute hypotension during vertebroplasty in sheep. Verbal presentation at the Combined New Zealand and Australian Orthopaedic Associations (NZOA/AOA) Conference, Queenstown.
2000
Chapter in Book - Research
Swope, J. A., Kasabov, N. K., & Williams, M. J. A. (2000). Neuro-fuzzy modelling of heart rate signals and applications to diagnostics. In P. S. Szczepaniak, P. J. G. Lisboa & J. Kacprzyk (Eds.), Fuzzy Systems in Medicine. (pp. 519-542). Heidelberg: Physica Verlag.
Journal - Research Article
Williams, M. J. A., Low, C., Wilkins, G. T., & Stewart, R. A. (2000). Randomised comparison of the effects of nicardipine and esmolol on coronary artery wall stress: implications for the risk of plaque rupture and acute coronary events. Heart, 84, 383-389.
Williams, M. J. A., McCormick, M., Kay, I. P., & Restieaux, N. J. (2000). Improved coronary flow after coronary angioplasty in patients with unstable angina. Australian & New Zealand Journal of Medicine, 30, 226-230.
Williams, M. J. A. (2000). Echocardiographic evaluation of stroke. New Zealand Medical Journal, 113, 36-38.
Journal - Professional & Other Non-Research Articles
Williams, M. J. A. (2000). Endothelial function and coronary artery disease. Shadows, 43(3), 6-8.
1999
Journal - Research Article
Williams, M. J., Sutherland, W. H. F., McCormick, M. P., de Jong, S. A., Walker, R. J., & Wilkins, G. T. (1999). Impaired endothelial function after a meal rich in used cooking fat. JACC, 33, 1050-1055.
Sutherland, W. H. F., Williams, M. J. A., Nye, E. R., Restieaux, N. J., de Jong, S. A., & Walker, H. (1999). Associations of plasma noncholesterol sterol levels with severity of coronary artery disease. Nutrition, Metabolism & Cardiovascular Diseases, 8, 386-391.
Kay, I. P., & Williams, M. J. A. (1999). Spontaneous coronary artery dissection: long stenting in a patient with polycythaemia vera. International Journal of Cardiovascular Interventions, 2, 191-193.
Williams, M. J. A., Stewart, R. A., Low, C., & Wilkins, G. T. (1999). Assessment of the mechanical properties of coronary arteries using intravascular ultrasound: an in vivo study. International Journal of Cardiac Imaging, 15, 287-294.
Williams, M. J. A., & Stewart, R. A. (1999). Coronary artery flow 10 weeks after myocardial infarction or unstable angina: effects of a combination of warfarin and aspirin. International Journal of Cardiology, 69, 19-25.
1998
Journal - Research Article
Williams, M. J. A., Kay, I. P., & Wilkins, G. T. (1998). Spontaneous coronary artery dissection presenting as unstable angina. Journal of Invasive Cardiology, 10, 274-276.
Williams, M. J. A., Restieaux, N. J. A., & Low, C. (1998). Myocardial infarction in young persons with normal coronary arteries. Heart, 79, 191-194.
Sutherland, W. H. F., Restieaux, N. J., Nye, E. R., Williams, M. J. A., de Jong, S. A., Robertson, M. C., & Walker, H. (1998). IDL composition and angiographically determined progression of atherosclerotic lesions during simvastin therapy. Arteriosclerosis, Thrombosis, & Vascular Biology, 18, 577-583.
Conference Contribution - Published proceedings: Full paper
Kozma, R., Swope, J. A., Kasabov, N. K., & Williams, M. J. A. (1998). Multi-agent implementation of fractal analysis by fuzzy neural networks. In N. K. Kasabov, R. Kozma, K. Ko, Shea, G. Coghill & T. Gedeon (Eds.), Progress in Connectionist-Based Information Systems: Proceedings of the 1997 International Conference on Neural Information Processing and Intelligent Information Systems (ICONIP/ANZIIS/ANNES'97). 1, (pp. 162-165). Singapore: Springer. [Full Paper]
1997
Journal - Research Article
Williams, M. J. A., & Stewart, R. A. H. (1997). Serial angiography in cocaine-induced myocardial infarction. Chest, 111(3), 822-824.
Shaw, D. P., Rutherford, J. S., & Williams, M. J. A. (1997). The mechanism of blood flow in cardiopulmonary resuscitation: Introducing the lung pump. Resuscitation, 35(3), 255-258.
Kerr, A. J., Williams, M. J. A., & Wilkins, G. T. (1997). Primary stenting as treatment for coronary-subclavian steal syndrome. Australian & New Zealand Journal of Medicine, 27(1), 80-81.
Williams, M. J. A., Morison, I. M., Parker, J. H., & Stewart, R. A. H. (1997). Progression of the culprit lesion in unstable coronary artery disease with warfarin and aspirin versus aspirin alone: preliminary study. JACC, 30(2), 364-369.
Williams, M. J. A., Lee, M. Y., DiSalvo, T. G., Dec, G. W., Semigran, M. J., Levine, R. A., & Picard, M. H. (1997). Tricuspid regurgitation and right heart dimensions at early and late follow-up after orthotopic cardiac transplantation. Echocardiography, 14(2), 111-117.
Conference Contribution - Published proceedings: Full paper
Kozma, R., Kasabov, N. K., Swope, J. A., & Williams, M. J. A. (1997). Combining neuro-fuzzy and chaos methods for intelligent time series analysis: case study of heart rate variability. IEEE International Conference on Systems, Man, and Cybernetics: October 1997, Orlando, FL. 4, (pp. 3025-3029). Los Alamitos, CA: IEEE Computer Society Press. [Full Paper]
1996
Journal - Research Article
Williams, M. J. A., Dow, C. J., Palacios, I. F., & Picard, M. H. (1996). Prevalence and timing of regional myocardial dysfunction after rotational coronary atherectomy. JACC, 28(4), 861-869.
Williams, M. J. A., Lee, M. Y., DiSalvo, T. G., Picard, M. H., Palacios, I. F., & Semigran, M. J. (1996). Biopsy-induced flail tricuspid leaflet and tricuspid regurgitation following orthotopic cardiac transplantation. American Journal of Cardiology, 77, 1339-1344.
Williams, M. J. A., Low, C., & Restieaux, N. J. (1996). Tachycardia and cardiomyopathy. New Zealand Medical Journal, 109, 78-79.
1995
Journal - Research Article
Williams, M. J. A., McClements, B. M., & Picard, M. H. (1995). Improvement of transthoracic pulmonary venous flow Doppler signal with intravenous injection of sonicated albumin. JACC, 26, 1741-1746.
Conference Contribution - Published proceedings: Abstract
Williams, M. J. A., Hammond-Tooke, G. D., & Restieaux, N. J. (1995). Hypokalaemic periodic paralysis with cardiac arrhythmia and prolonged QT interval. Australian and New Zealand Journal of Medicine. 25(5), (pp. 549). [Abstract]