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Contact Details

Phone
64 3 474 0999 ext 58079
Email
michael.williams@otago.ac.nz
Position
Clinical Professor
Department
Department of Medicine (Dunedin)
Qualifications
MD FRACP FACC
Research summary
Cardiology
Teaching
Integration of cardiac investigations into clinical practice.
Clinical
  • Echocardiography.
  • Interventional cardiology.
  • General cardiology.

Research

Michael Williams' research interests include studying the effect of lifestyle factors and diet on arterial function and the development of arterial disease. He has investigated the influence of physical fitness on measures of arterial inflammation and the risk of developing chest pain and heart attack in later life. His other clinical research has focussed on understanding the biology of restenosis in stents inserted in patients' heart arteries to open blockages. Studies of cardiovascular genetics have contributed to international collaborative research and the identification of novel genetic markers of arterial disease. Michael's current investigations include the regulation of gene expression on the development of narrowing and stiffening of cardiac valves with the aim of developing therapies to delay or prevent the requirement for surgical valve replacement. He is presently Chair of the Medicine Department Peer Review Committee.

Publications

Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Williams, M. J. A., Gwynne-Jones, D. P., & Thomas, K. N. (2025). The effect of pre-operative cardiorespiratory fitness on functional and subjective outcomes following total hip and knee arthroplasty: A single centre, observational study. New Zealand Medical Journal/Te ara tika o te hauora hapori, 138(1614), 19-41. Retrieved from https://www.nzmj.org.nz/ Journal - Research Article

Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Williams, M. J. A., & Thomas, K. N. (2025). Both hot- and thermoneutral-water immersion reduce 24-h blood pressure in people with hypertension: A randomized crossover study. Temperature. Advance online publication. doi: 10.1080/23328940.2025.2465025 Journal - Research Article

Moore, M. K., Jones, G. T., Whalley, G., Williams, M. J. A., Stewart, R. A., & Coffey, S. (2025). The prevalence of aortic stenosis in Maōri undergoing clinically indicated echocardiography compared to New Zealand Europeans. New Zealand Medical Journal/Te ara tika o te hauora hapori, 138(1608), 84-93. Retrieved from https://www.nzmj.org.nz/ Journal - Research Article

Moore, M. K., Jones, G. T., Whalley, G., Prendergast, B. D., Williams, M. J. A., & Coffey, S. (2024). Cardiac damage predicts the outcome of calcific aortic valve disease regardless of the severity of aortic stenosis. European Heart Journal, 45(Suppl. 1), ehae666.1881. doi: 10.1093/eurheartj/ehae666.1881 Conference Contribution - Published proceedings: Abstract

Tonkin, D., Williams, M., Schwenke, D., & Katare, R. (2024, August-September). Investigating microRNA therapeutics in a 3D model of the failing heart. Poster session presented at the 18th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)

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