Red X iconGreen tick iconYellow tick icon

Contact Details

64 3 474 7775 (Dunedin Hospital ext 8641)
Research Fellow
Department of Medicine (Dunedin)
BSc(Hons)(Massey) PhD(Otago)
Research summary
Molecular basis of polycystic kidney disease


My main research interest is the study of a human disease called Autosomal Dominant Polycystic Kidney Disease (ADPKD). This disorder affects up to 1 in 500 individuals and is a significant cause of renal failure in the population. I am interested in identifying the molecular pathways that lead to the progression of this disease, and investigating potential therapies for this condition.


Bowden, S. A., Rodger, E. J., Chatterjee, A., Eccles, M. R., & Stayner, C. (2021). Recent discoveries in epigenetic modifications of polycystic kidney disease. International Journal of Molecular Sciences, 22(24), 13327. doi: 10.3390/ijms222413327 Journal - Research Other

McDougall, L., Kueh, J. T. B., Ward, J., Tyndall, J. D. A., Woolley, A. G., Mehta, S., Stayner, C., Larsen, D. S., & Eccles, M. R. (2021). Chemical synthesis of the PAX protein inhibitor EG1 and its ability to slow the growth of human colorectal carcinoma cells. Frontiers in Oncology, 11, 709540. doi: 10.3389/fonc.2021.709540 Journal - Research Article

Bowden, S. A., Stockwell, P. A., Rodger, E. J., Parry, M. F., Eccles, M. R., Stayner, C., & Chatterjee, A. (2020). Extensive inter-cyst DNA methylation variation in autosomal dominant polycystic kidney disease revealed by genome scale sequencing. Frontiers in Genetics, 11, 348. doi: 10.3389/fgene.2020.00348 Journal - Research Article

Macdonald, C. M., Kunnen, B., Stayner, C., & Eccles, M. R. (2019). Designing phantoms to accurately replicate circular depolarization in biological scattering media. Applied Optics, 58(35), 9577-9584. doi: 10.1364/AO.58.009577 Journal - Research Article

Stayner, C., Brooke, D. G., Bates, M., & Eccles, M. R. (2019). Targeted therapies for autosomal dominant polycystic kidney disease. Current Medicinal Chemistry, 26(17), 3081-3102. doi: 10.2174/0929867325666180508095654 Journal - Research Article

Back to top