Contact Details
- Phone
- 64 3 595 6869
- tracy.melzer@nzbri.org
University Links
- Position
- Research Associate Professor and MRI Research Manager
- Department
- Department of Medicine (Christchurch)
- Qualifications
- BA, BSc(Hons), PhD
- Research summary
- Parkinson's disease
Research
As MRI Research Manager at the NZ Brain Research Institute, I oversee all imaging at the NZBRI. This provides me with the opportunity to become involved in a wide range of neurological research, including child development, mild traumatic brain injury, post-traumatic stress disorder, neurodegenerative diseases, and more.
As an Associate Professor in the Department of Medicine, my primary focus is on the development and application of Magnetic Resonance Imaging (MRI) techniques to advance our understanding of cognitive decline in Parkinson’s disease.
Publications
Reuben, A., Richmond-Rakerd, L. S., Milne, B., Shah, D., Pearson, A., Hogan, S., Ireland, D., Keenan, R., Knodt, A. R., Melzer, T., Poulton, R., … Moffitt, T. E., & Caspi, A. (2024). Dementia, dementia's risk factors and premorbid brain structure are concentrated in disadvantaged areas: National register and birth-cohort geographic analyses. Alzheimer's & Dementia. Advance online publication. doi: 10.1002/alz.13727 Journal - Research Article
Newburn, G., Condron, P., Kwon, E. E., McGeown, J. P., Melzer, T. R., Bydder, M., … Bydder, G. M. (2024). Diagnosis of delayed post-hypoxic leukoencephalopathy (Grinker's Myelinopathy) with MRI using divided subtracted inversion recovery (dSIR) sequences: Time for reappraisal of the syndrome? Diagnostics, 14(4), 418. doi: 10.3390/diagnostics14040418 Journal - Research Article
Kerestes, R., Laansma, M. A., Owens-Walton, C., Perry, A., van Heese, E. M., Al-Bachari, S., Anderson, T. J., … Dalrymple-Alford, J. C., … Melzer, T. R., … Pitcher, T. L., … and the ENIGMA-Parkinson's Study. (2023). Cerebellar volume and disease staging in Parkinson's disease: An ENIGMA-PD study. Movement Disorders. Advance online publication. doi: 10.1002/mds.29611 Journal - Research Article
Chaffey, T., Roberts, R., Morgan, C., Melzer, T., Kirk, I., Dalrymple-Alford, J., Cutfield, N., Anderson, T., … New Zealand-Dementia Prevention Research Clinics. (2023). The relationship between cortical thinning, grey matter atrophy, and cognitive performance in mild cognitive impairment. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 72). Retrieved from https://www.awcbr.org Conference Contribution - Published proceedings: Abstract
Aye, W. W. T., Le Heron, C., Dalrymple-Alford, J., Keenan, R. J., Anderson, T. J., & Melzer, T. R. (2023). Early-phase amyloid PET as a cerebral perfusion surrogate in cognitively impaired Parkinson's disease. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 68). Retrieved from https://www.awcbr.org Conference Contribution - Published proceedings: Abstract
2024
Journal - Research Article
Reuben, A., Richmond-Rakerd, L. S., Milne, B., Shah, D., Pearson, A., Hogan, S., Ireland, D., Keenan, R., Knodt, A. R., Melzer, T., Poulton, R., … Moffitt, T. E., & Caspi, A. (2024). Dementia, dementia's risk factors and premorbid brain structure are concentrated in disadvantaged areas: National register and birth-cohort geographic analyses. Alzheimer's & Dementia. Advance online publication. doi: 10.1002/alz.13727
Newburn, G., Condron, P., Kwon, E. E., McGeown, J. P., Melzer, T. R., Bydder, M., … Bydder, G. M. (2024). Diagnosis of delayed post-hypoxic leukoencephalopathy (Grinker's Myelinopathy) with MRI using divided subtracted inversion recovery (dSIR) sequences: Time for reappraisal of the syndrome? Diagnostics, 14(4), 418. doi: 10.3390/diagnostics14040418
2023
Journal - Research Article
Kerestes, R., Laansma, M. A., Owens-Walton, C., Perry, A., van Heese, E. M., Al-Bachari, S., Anderson, T. J., … Dalrymple-Alford, J. C., … Melzer, T. R., … Pitcher, T. L., … and the ENIGMA-Parkinson's Study. (2023). Cerebellar volume and disease staging in Parkinson's disease: An ENIGMA-PD study. Movement Disorders. Advance online publication. doi: 10.1002/mds.29611
Gooch, E. A., Horne, K.-L., Melzer, T. R., McAuliffe, M. J., MacAskill, M., Dalrymple-Alford, J. C., Anderson, T. J., & Theys, C. (2023). Acquired stuttering in Parkinson's disease. Movement Disorders Clinical Practice, 13758. Advance online publication. doi: 10.1002/mdc3.13758
Whitman, E. T., Knodt, A. R., Elliott, M. L., Abraham, W. C., Cheyne, K., Hogan, S., Ireland, D., Keenan, R., Leung, J. H., Melzer, T. R., Poulton, R., Purdy, S., Ramrakha, S., … Hariri, A. R. (2023). Functional topography of the neocortex predicts covariation in complex cognitive and basic motor abilities. Cerebral Cortex, 33, 8218-8231. doi: 10.1093/cercor/bhad109
Morris, L.-A., Harrison, S. J., Melzer, T. R., Dalrymple-Alford, J. C., Anderson, T. J., MacAskill, M. R., & Le Heron, C. J. (2023). Altered nucleus accumbens functional connectivity precedes apathy in Parkinson's disease. Brain, 146, 2739-2752. doi: 10.1093/brain/awad113
Barrett-Young, A., Abraham, W. C., Cheung, C. Y., Gale, J., Hogan, S., Ireland, D., Keenan, R., … Melzer, T. R., Moffitt, T. E., Ramrakha, S., … Wilson, G. A., … Poulton, R. (2023). Associations between thinner retinal neuronal layers and suboptimal brain structural integrity in a middle-aged cohort. Eye & Brain, 15, 25-35. doi: 10.2147/EB.S402510
Almuqbel, M. M., Palmer, N. J., Jenkins, A., Keenan, R. J., & Melzer, T. R. (2023). Magnetic resonance imaging of breast implants: Optimizing tissue contrast. Journal of Medical Imaging & Radiation Sciences. Advance online publication. doi: 10.1016/j.jmir.2022.12.001
Murray, S. J., Almuqbel, M. M., Felton, S. A., Palmer, N. J., Myall, D. J., Shoorangiz, R., … Palmer, D. N., Melzer, T. R., & Mitchell, N. L. (2023). Progressive MRI brain volume changes in ovine models of CLN5 and CLN6 neuronal ceroid lipofuscinosis. Brain Communications, 5(1), fcac339. doi: 10.1093/braincomms/fcac339
Tippett, L. J., Cawston, E. E., Morgan, C. A., Melzer, T. R., Brickell, K. L., Ilse, C., … Le Heron, C., Buchanan, S., … Anderson, T. J., Williams, J. M., Cutfield, N. J., Dalrymple-Alford, J. C., … the NZ-DPRC. (2023). Dementia Prevention Research Clinic: A longitudinal study investigating factors influencing the development of Alzheimer’s disease in Aotearoa, New Zealand. Journal of the Royal Society of New Zealand, 53(4), 489-510. doi: 10.1080/03036758.2022.2098780
MacAskill, M. R., Pitcher, T. L., Melzer, T. R., Myall, D. J., Horne, K.-L., Shoorangiz, R., … Livingston, L., … Pascoe, M. J., Marshall, E. T., … Perry, S. E., Meissner, W. G., … Le Heron, C. J., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2023). The New Zealand Parkinson’s progression programme. Journal of the Royal Society of New Zealand, 53(4), 466-488. doi: 10.1080/03036758.2022.2111448
Conference Contribution - Published proceedings: Abstract
Chaffey, T., Roberts, R., Morgan, C., Melzer, T., Kirk, I., Dalrymple-Alford, J., Cutfield, N., Anderson, T., … New Zealand-Dementia Prevention Research Clinics. (2023). The relationship between cortical thinning, grey matter atrophy, and cognitive performance in mild cognitive impairment. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 72). Retrieved from https://www.awcbr.org
Aye, W. W. T., Le Heron, C., Dalrymple-Alford, J., Keenan, R. J., Anderson, T. J., & Melzer, T. R. (2023). Early-phase amyloid PET as a cerebral perfusion surrogate in cognitively impaired Parkinson's disease. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 68). Retrieved from https://www.awcbr.org
Lee, R. M., Shoorangiz, R., Foulds, J. A., Almuqbel, M. M., Le Heron, C., Cleland, L., Keenan, R. J., Mulder, R., Porter, R. J., Newton-Howes, G., Douglas, K. M., Butler, A. P. H., Boden, J. M., & Melzer, T. R. (2023). Long-term impacts of cannabis on resting state functional networks: Are there any? In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 57). Retrieved from https://www.awcbr.org
Ganderton, J., Pitcher, T., Melzer, T., Philips, S., Harris, A., Dobson, R., Anderson, T., … Dalrymple-Alford, J. (2023). Reflex tears to target alpha-synuclein in Parkinson's disease. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 51). Retrieved from https://www.awcbr.org
Harris, A. L., Melzer, T. R., Myall, D., Shoorangiz, R., Slater, N. M., Hall-McMaster, G., Livingston, L., Grenfell, S., … Anderson, T. J., & Dalrymple-Alford, J. C. (2023). Grey matter and cognitive impairment in Parkinson's disease. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 36). Retrieved from https://www.awcbr.org
Horne, K.-L., Harrison, S. J., Slater, N. M., Morris, L.-A., Myall, D. J., Melzer, T. R., Pitcher, T. L., Dalrymple-Alford, J. C., Anderson, T. J., & Le Heron, C. (2023). Understanding the development of anxiety over the disease course in Parkinson's disease. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 30). Retrieved from https://www.awcbr.org
Slater, N. M., Shoorangiz, R., Myall, D. J., Horne, K.-L., Anderson, T. J., Melzer, T. R., & Dalrymple-Alford, J. C. (2023). Cortical cholinergic pathway integrity in Parkinson's disease. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 29). Retrieved from https://www.awcbr.org
Other Research Output
Eglinton, T., Hooper, G., Woodfield, T., & Melzer, T. (2023, July). Surgery and medicine of the future: AI, robotics and “smart” implants. Public Talk Series: Celebrating 50 years of University of Otago Christchurch, Otautahi, New Zealand. Retrieved from https://events.otago.ac.nz/christchurch50/surgeryandmedicine/Site/Register
2022
Journal - Research Article
Carlisi, C. O., Moffitt, T. E., Knodt, A. R., Harrington, H., Langevin, S., Ireland, D., Melzer, T. R., Poulton, R., Ramrakha, S., Caspi, A., … Viding, E. (2022). Association of subcortical gray-matter volumes with life-course-persistent antisocial behavior in a population-representative longitudinal birth cohort. Development & Psychopathology, 34(5), 2012-2022. doi: 10.1017/S0954579421000377
Zhao, Y., van Heese, E., Laansma, M. A., Al-Bachari, S., Anderson, T., Assogna, F., … Dalrymple-Alford, J., … Melzer, T. R., … Pitcher, T., … Gutman, B. A. (2022). TV-L1 ordinal logistic regression reveals new morphometric patterns related to Parkinsonian symptom severity: An ENIGMA-PD study. Alzheimer's & Dementia, 18(Suppl. 6), e067037. doi: 10.1002/alz.067037
Morgan, C. A., Roberts, R. P., Chaffey, T., Tahara-Eckl, L., van der Meer, M., Günther, M., Anderson, T. J., … Dalrymple-Alford, J. C., … Melzer, T. R. (2022). Reproducibility and repeatability of magnetic resonance imaging in dementia. Physica Medica, 101, 8-17. doi: 10.1016/j.ejmp.2022.06.012
Conference Contribution - Published proceedings: Full paper
Zhao, Y., Laansma, M. A., van Heese, E. M., Owens-Walton, C., Parkes, L. M., Debove, I., … Anderson, T. J., … Melzer, T. R., Pitcher, T. L., … and for the ENIGMA consortium. (2022). Learning interpretable regularized ordinal models from 3D mesh data for neurodegenerative disease staging. In A. Abdulkadir, D. R. Bathula, N. C. Dvornek, M. Habes, S. Mostafa Kia, V. Kumar & T. Wolfers (Eds.), Machine Learning in Clinical Neuroimaging: Proceedings of the 5th International Workshop, held in conjunction with the 25th International Conference on Medical Imaging Computing and Computer Assisted Intervention (MICCAI): Lecture notes in computer science (Vol. 13596). (pp. 115-124). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-17899-3_12
Conference Contribution - Published proceedings: Abstract
Le Heron, C., MacAskill, M., Horne, K.-L., Livingston, L., Melzer, T., Myall, D., Pitcher, T., Dalrymple-Alford, J., Anderson, T., & Harrison, S. (2022). Temporal dynamics and longitudinal predictors of apathy in Parkinson's disease. Movement Disorders, 37(Suppl. 2), (pp. S630). doi: 10.1002/mds.29223
Slater, N., Shoorangiz, R., Hall-McMaster, G., Harris, A., Livingston, L., Grenfell, S., … Anderson, T., Melzer, T., & Dalrymple-Alford, J. (2022). Parkinson's disease and nucleus basalis of Meynert integrity: Cognition and everyday function. Movement Disorders, 37(Suppl. 2), (pp. S95). doi: 10.1002/mds.29223
Shoorangiz, R., Slater, N., Hall-McMaster, G., Peterson, E., Livingston, L., Grenfell, S., … Jones, R., Anderson, T., Melzer, T., & Dalrymple-Alford, J. (2022). EEG power-spectra parametrization and cognitive ability in Parkinson's disease. Movement Disorders, 37(Suppl. 2), (pp. S94-S95). doi: 10.1002/mds.29223
Nolan, D., Myall, D., Morgan, C., Shoorangiz, R., Livingston, L., Grenfell, S., Pitcher, T., MacAskill, M., Horne, K.-L., Le Heron, C., … Dalrymple-Alford, J., Anderson, T., & Melzer, T. (2022). MRI to investigate cerebrovascular changes in Parkinson's disease. Movement Disorders, 37(Suppl. 2), (pp. S87). doi: 10.1002/mds.29223
Aye, W. W. T., Melzer, T. R., Keenan, R. J., Croucher, M. J., Tippett, L. J., Anderson, T. J., & Le Heron, C. (2022). Early phase amyloid PET as a surrogate marker of brain metabolism in neurodegenerative disorders. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 88). Retrieved from https://www.queenstownresearchweek.org
Hall-McMaster, G., Shoorangiz, R., Slater, N. M., Peterson, E., Harris, A., Livingston, L., Grenfell, S., Clifford, K., Anderson, T., Melzer, T., & Dalrymple-Alford, J. (2022). Alterations in normalised EEG power across the cognitive spectrum in Parkinson's disease. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 83). Retrieved from https://www.queenstownresearchweek.org
Slater, N. M., Shoorangiz, R., Hall-McMaster, G., Harris, A. L., Livingston, L., Grenfell, S., Clifford, K. J., Anderson, T. J., Melzer, T. R., & Dalrymple-Alford, J. C. (2022). Cholinergic basal forebrain integrity and cognition in Parkinson's disease. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 75). Retrieved from https://www.queenstownresearchweek.org
Tahara-Eckl, L., Roberts, R., Morgan, C., Dell'Acqua, F., Kirk, I., Melzer, T. R., Dalrymple-Alford, J. C., Anderson, T. J., Cutfield, N. J., & Tippett, L. (2022). Poorer executive function performance is associated with lower white matter fibre in the superior longitudinal fasciculus in Alzheimer's disease risk groups. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 70). Retrieved from https://www.queenstownresearchweek.org
Deane, A. R., Shoorangiz, R., Schwartz, D., Silbert, L. C., Dalrymple-Alford, J. C., Anderson, T. J., & Melzer, T. R. (2022). Parkinson's disease: The role of perivascular spaces in cognitive decline. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 70). Retrieved from https://www.queenstownresearchweek.org
Lee, R. M., Cleland, L., Foulds, J. A., Shoorangiz, R., Almuqbel, M. M., Le Heron, C., Keenan, R., Mulder, R., Porter, R., Newton-Howes, G., Douglas, K., Butler, A., Boden, J. M., & Melzer, T. R. (2022). Early cannabis use and its impact on the ageing brain: An MRI study of a New Zealand longitudinal birth cohort. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 51). Retrieved from https://www.queenstownresearchweek.org
Morris, L.-A., Harrison, S., MacAskill, M., Anderson, T., Melzer, T., Dalrymple-Alford, J., & Le Heron, C. (2022). Altered nucleus accumbens functional connectivity predicts apathy development in Parkinson's disease. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 42). Retrieved from https://www.queenstownresearchweek.org
Harris, A., Melzer, T. R., Shoorangiz, R., Slater, N. M., Hall-McMaster, G., Livingston, L., Grenfell, S., Clifford, K. J., MacAskill, M. R., Anderson, T. J., & Dalrymple-Alford, J. C. (2022). Parkinson's disease: Neuroanatomical differences and correlates of cognitive impairement. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 32). Retrieved from https://www.queenstownresearchweek.org
2021
Journal - Research Article
Morgan, C. A., Melzer, T. R., Roberts, R. P., Wiebels, K., Mutsaerts, H. J. M. M., Spriggs, M. J., … Anderson, T. J., Cutfield, N. J., … Tippett, L. J. (2021). Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia. Scientific Reports, 11, 23325. doi: 10.1038/s41598-021-02313-z
Laansma, M. A., Bright, J. K., Al-Bachari, S., Anderson, T. J., Ard, T., Assogna, F., … Dalrymple-Alford, J., … Melzer, T. R., … Pitcher, T. L., … and the ENIGMA-Parkinson's Study. (2021). International multicenter analysis of brain structure across clinical stages of Parkinson's disease. Movement Disorders, 36(11), 2583-2594. doi: 10.1002/mds.28706
d'Arbeloff, T., Elliott, M. L., Knodt, A. R., Sison, M., Melzer, T. R., Ireland, D., Ramrakha, S., Poulton, R., Caspi, A., Moffitt, T. E., & Hariri, A. R. (2021). Midlife cardiovascular fitness is reflected in the brain's white matter. Frontiers in Aging Neuroscience, 13, 652575. doi: 10.3389/fnagi.2021.652575
Murray, S. J., Russell, K. N., Melzer, T. R., Gray, S. J., Heap, S. J., Palmer, D. N., & Mitchell, N. L. (2021). Intravitreal gene therapy protects against retinal dysfunction and degeneration in sheep with CLN5 Batten disease. Experimental Eye Research, 207, 108600. doi: 10.1016/j.exer.2021.108600
Elliott, M. L., Caspi, A., Houts, R. M., Ambler, A., Broadbent, J. M., Hancox, R. J., … Hogan, S., Keenan, R., … Melzer, T. R., … Ramrakha, S., … Righarts, A., … Thomson, W. M., Thorne, P. R., … Wilson, G., … Poulton, R., & Moffitt, T. E. (2021). Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy. Nature Aging, 1(3), 295-308. doi: 10.1038/s43587-021-00044-4
Basukala, D., Mukundan, R., Lim, A., Hurrell, M. A., Keenan, R. J., Dalrymple-Alford, J. C., Anderson, T. J., Myall, D. J., & Melzer, T. R. (2021). Automated segmentation of substantia nigra and red nucleus using quantitative susceptibility mapping images: Application to Parkinson's disease. Computers & Electrical Engineering, 91, 107091. doi: 10.1016/j.compeleceng.2021.107091
Horne, K.-L., MacAskill, M. R., Myall, D. J., Livingston, L., Grenfell, S., Pascoe, M. J., … Shoorangiz, R., Melzer, T. R., Pitcher, T. L., Anderson, T. J., & Dalrymple-Alford, J. C. (2021). Neuropsychiatric symptoms are associated with dementia in Parkinson's disease but not predictive of it. Movement Disorders Clinical Practice, 8(3), 390-399. doi: 10.1002/mdc3.13151
Wheelock, M. D., Lean, R. E., Bora, S., Melzer, T. R., Eggebrecht, A. T., Smyser, C. D., & Woodward, L. J. (2021). Functional connectivity network disruption underlies domain-specific impairments in attention for children born very preterm. Cerebral Cortex, 31, 1383-1394. doi: 10.1093/cercor/bhaa303
Romer, A. L., Elliott, M. L., Knodt, A. R., Sison, M. L., Ireland, D., Houts, R., Ramrakha, S., Poulton, R., Keenan, R., Melzer, T. R., … Hariri, A. R. (2021). Pervasively thinner neocortex as a transdiagnostic feature of general psychopathology. American Journal of Psychiatry, 178(2), 174-182. doi: 10.1176/appi.ajp.2020.19090934
Elliott, M. L., Belsky, D. W., Knodt, A. R., Ireland, D., Melzer, T. R., Poulton, R., Ramrakha, S., Caspi, A., Moffitt, T. E., & Hariri, A. R. (2021). Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort. Molecular Psychiatry, 26, 3829-3838. doi: 10.1038/s41380-019-0626-7
Romer, A. L., Knodt, A. R., Sison, M. L., Ireland, D., Houts, R., Ramrakha, S., Poulton, R., Keenan, R., Melzer, T. R., Moffitt, T. E., Caspi, A., & Hariri, A. R. (2021). Replicability of structural brain alterations associated with general psychopathology: Evidence from a population-representative birth cohort. Molecular Psychiatry, 26, 3839-3846. doi: 10.1038/s41380-019-0621-z
Conference Contribution - Published proceedings: Abstract
Horne, K.-L., MacAskill, M. R., Myall, D. J., Livingston, L., Grenfell, S., Pascoe, M. J., … Shoorangiz, R., Melzer, T. R., Pitcher, T. L., Dalrymple-Alford, J. C., & Anderson, T. J. (2021). Hallucinations in Parkinson's disease: Are they predictive of dementia? New Zealand Medical Journal, 134(1539), (pp. 88-89). Retrieved from https://www.nzma.org.nz/journal
Working Paper; Discussion Paper; Technical Report
Carlisi, C. O., Moffitt, T. E., Knodt, A. R., Harrington, H., Langevin, S., Ireland, D., Melzer, T. R., Poulton, R., Ramrakha, S., Caspi, A., … Viding, E. (2021). Association of subcortical grey-matter volumes with life-course-persistent antisocial behavior in a population-representative longitudinal birth cohort. PsyArXiv. doi: 10.31234/osf.io/st2db
2020
Journal - Research Article
d'Arbeloff, T., Cooke, M., Knodt, A. R., Sison, M., Melzer, T. R., Ireland, D., Poulton, R., Ramrakha, S., Moffitt, T. E., Caspi, A., & Hariri, A. R. (2020). Is cardiovascular fitness associated with structural brain integrity in midlife? Evidence from a population-representative birth cohort study. Aging, 12(20), 20888-20914. doi: 10.18632/aging.104112
Hofer, E., Roshchupkin, G. V., Adams, H. H. H., Knol, M. J., Lin, H., Li, S., … ENIGMA consortium, including Pitcher, T. L., Melzer, T. R., Anderson, T. J., … Seshadri, S. (2020). Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications, 11, 4796. doi: 10.1038/s41467-020-18367-y
Darlow, B. A., Woodward, L. J., Levin, K. J., Melzer, T., & Horwood, L. J. (2020). Perinatal and childhood predictors of general cognitive outcome at 28 years in a very-low-birthweight national cohort. Developmental Medicine & Child Neurology, 62, 1423-1428. doi: 10.1111/dmcn.14649
Carlisi, C. O., Moffitt, T. E., Knodt, A. R., Harrington, H., Ireland, D., Melzer, T. R., Poulton, R., Ramrakha, S., … Viding, E. (2020). Associations between life-course-persistent antisocial behaviour and brain structure in a population-representative longitudinal birth cohort. Lancet Psychiatry, 7(3), 245-253. doi: 10.1016/s2215-0366(20)30002-x
Melzer, T. R., Keenan, R. J., Leeper, G. J., Kingston-Smith, S., Felton, S. A., Green, S. K., … Almuqbel, M. M., & Myall, D. J. (2020). Test-retest reliability and sample size estimates after MRI scanner relocation. NeuroImage, 211, 116608. doi: 10.1016/j.neuroimage.2020.116608
Theys, C., Kovacs, S., Peeters, R., Melzer, T. R., van Wieringen, A., & De Nil, L. F. (2020). Brain activation during non-habitual speech production: Revisiting the effects of simulated disfluencies in fluent speakers. PLoS ONE, 15(1), e0228452. doi: 10.1371/journal.pone.0228452
Borlase, N., Melzer, T. R., Eggleston, M. J. F., Darling, K. A., & Rucklidge, J. J. (2020). Resting-state networks and neurometabolites in children with ADHD after 10 weeks of treatment with micronutrients: Results of a randomised placebo-controlled trial. Nutritional Neuroscience, 23(11), 876-886. doi: 10.1080/1028415x.2019.1574329
Snell, D. L., Martin, R., Surgenor, L. J., Siegert, R. J., Hay-Smith, E. J. C., Melzer, T. R., Anderson, T. J., & Hooper, G. J. (2020). Wrestling with uncertainty after mild traumatic brain injury: A mixed methods study. Disability & Rehabilitation, 42(14), 1942-1953. doi: 10.1080/09638288.2018.1542461
Conference Contribution - Poster Presentation (not in published proceedings)
Laansma, M., Bright, J., Gutman, B., Rummel, C., Wiest, R., Debove, I., … Pitcher, T., Melzer, T., … Van der Werf, Y. (2020, June-July). Mega-analysis shows brain structure abnormalities related to disease severity in Parkinson's disease. Poster session presented at the Organization for Human Brain Mapping (OHBM) 26th Annual Meeting, [Online].
2019
Journal - Research Article
d'Arbeloff, T., Elliott, M. L., Knodt, A. R., Melzer, T. R., Keenan, R., Ireland, D., Ramrakha, S., Poulton, R., Anderson, T., … Hariri, A. R. (2019). White matter hyperintensities are common in midlife and already associated with cognitive decline. Brain Communications, 1(1), fcz041. doi: 10.1093/braincomms/fcz041
Ella, A., Barriére, D. A., Adriaensen, H., Palmer, D. N., Melzer, T. R., Mitchell, N. L., & Keller, M. (2019). The development of brain magnetic resonance approaches in large animal models for preclinical research. Animal Frontiers, 9(3), 44-51. doi: 10.1093/af/vfz024
Douglas, K. M., Groves, S., Porter, R. J., Jordan, J., Wilson, L., Melzer, T. R., … Bell, C. J. (2019). Traumatic imagery following glucocorticoid administration in earthquake-related post-traumatic stress disorder: A preliminary functional magnetic resonance imaging study. Australian & New Zealand Journal of Psychiatry, 53(12), 1167-1178. doi: 10.1177/0004867419851860
Melzer, T. R., Stark, M. R., Keenan, R. J., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Grenfell, S., Horne, K.-L., … Pascoe, M., Almuqbel, M. M., … Miller, D. H., Dalrymple-Alford, J. C., & Anderson, T. J. (2019). Beta amyloid deposition is not associated with cognitive impairment in Parkinson’s Disease. Frontiers in Neurology, 10, 391. doi: 10.3389/fneur.2019.00391
Pascoe, M. J., Melzer, T. R., Horwood, L. J., Woodward, L. J., & Darlow, B. A. (2019). Altered grey matter volume, perfusion and white matter integrity in very low birthweight adults. NeuroImage: Clinical, 22, 101780. doi: 10.1016/j.nicl.2019.101780
Elliott, M. L., Knodt, A. R., Cooke, M., Kim, M. J., Melzer, T. R., Keenan, R., Ireland, D., Ramrakha, S., Poulton, R., … Hariri, A. R. (2019). General functional connectivity: Shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks. NeuroImage, 189, 516-532. doi: 10.1016/j.neuroimage.2019.01.068
Conference Contribution - Published proceedings: Full paper
Basukala, D., Mukundan, R., Melzer, T., & Keenan, R. (2019). Segmentation of substantia nigra using weighted thresholding method. Proceedings of the 2018 International Conference on Image and Vision Computing New Zealand (IVCNZ). IEEE. doi: 10.1109/IVCNZ.2018.8634679
Conference Contribution - Published proceedings: Abstract
Stark, M., Melzer, T., Myall, D., Keenan, R., Pitcher, T., Horne, K.-L., Livingston, L., MacAskill, M., Dalrymple-Alford, J., & Anderson, T. (2019). Amyloid load and cognitive decline in Parkinson's disease: Preliminary longitudinal findings. Movement Disorders, 34(Suppl. 2), (pp. S831). doi: 10.1002/mds.27795
Horne, K.-L., Shoorangiz, R., Livingston, L., Grenfell, S., Almuqbel, M., Young, B., … MacAskill, M., Myall, D., Pitcher, T., Anderson, T., Dalrymple-Alford, J., & Melzer, T. (2019). Association of MRI-derived estimated brain age and cognitive ability in Parkinson's disease. Movement Disorders, 34(Suppl. 2), (pp. S796). doi: 10.1002/mds.27795
Horne, K.-L., Shoorangiz, R., Livingston, L., Grenfell, S., Almuqbel, M., Young, B., MacAskill, M. R., Myall, D. J., Anderson, T. J., Dalrymple-Alford, J. C., & Melzer, T. R. (2019). MRI-derived estimated brain-age and cognitive decline in Parkinson's disease. In K. Hillman (Ed.), Proceedings of the 37th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 65). Retrieved from http://www.otago.ac.nz/awcbr
Jay, S., Melzer, T., & Snell, D. (2019). Grey and white matter health after Mild Traumatic Brian Injury. ANZ Journal of Surgery, 89(Suppl. 1), (pp. 210). doi: 10.1111/ans.15180
Jay, S., Melzer, T., & Snell, D. (2019). Chronic pain and advanced MRI techniques. ANZ Journal of Surgery, 89(Suppl. 1), (pp. 131). doi: 10.1111/ans.15180
Castellazzi, G., Martinelli, D., Collorone, S., Alhamadi, A., Debernard, L., Melzer, T. R., … Mason, D. F., … Wheeler-Kingshott, C. A. M. (2019). A clinical decision system based on resting state fMRI-derived features to predict the conversion of CIS to RRMS. Multiple Sclerosis Journal, 25(2, Suppl.), (pp. 686-687). doi: 10.1177/1352458519868081
Elliott, M., Knodt, A., Cooke, M., Kim, J., Melzer, T., Keenan, R., Ireland, D., Ramrakha, S., Poulton, R., … Hariri, A. (2019). General functional connectivity: Shared features of resting state and task fMRI drive reliable and heritable individual differences in functional brain networks. Biological Psychiatry, 85(10), (pp. S299). doi: 10.1016/j.biopsych.2019.03.758
d'Arbeloff, T., Elliott, M., Knodt, A., Melzer, T., Keenan, R., Ireland, D., Ramrakha, S., Poulton, R., … Hariri, A. (2019). White matter lesions are common in midlife and associated with cognitive decline. Biological Psychiatry, 85(10, Suppl.), (pp. S213). doi: 10.1016/j.biopsych.2019.03.539
2018
Journal - Research Article
Castellazzi, G., Debernard, L., Melzer, T. R., Dalrymple-Alford, J. C., D'Angelo, E., Miller, D. H., … Mason, D. F. (2018). Functional connectivity alterations reveal complex mechanisms based on clinical and radiological status in mild relapsing remitting multiple sclerosis. Frontiers in Neurology, 9, 690. doi: 10.3389/fneur.2018.00690
Russell, K. N., Mitchell, N. L., Anderson, N. G., Bunt, C. R., Wellby, M. P., Melzer, T. R., … Palmer, D. N. (2018). Computed tomography provides enhanced techniques for longitudinal monitoring of progressive intracranial volume loss associated with regional neurodegeneration in ovine neuronal ceroid lipofuscinoses. Brain & Behavior, 8, e01096. doi: 10.1002/brb3.1096
Wheelock, M. D., Austin, N. C., Bora, S., Eggebrecht, A. T., Melzer, T. R., Woodward, L. J., & Smyser, C. D. (2018). Altered functional network connectivity relates to motor development in children born very preterm. NeuroImage, 183, 574-583. doi: 10.1016/j.neuroimage.2018.08.051
Mitchell, N. L., Russell, K. N., Wellby, M. P., Wicky, H. E., Schoderboeck, L., Barrell, G. K., Melzer, T. R., … Hughes, S. M., & Palmer, D. N. (2018). Longitudinal in vivo monitoring of CNS demonstrates the efficacy of gene therapy in a sheep model of CLN5 Batten disease. Molecular Therapy, 26(10), 2366-2378. doi: 10.1016/j.ymthe.2018.07.015
Snell, D. L., Martin, R., Macleod, A. D., Surgenor, L. J., Siegert, R. J., Hay-Smith, E. J. C., Melzer, T., Hooper, G. J., & Anderson, T. (2018). Untangling chronic pain and post-concussion symptoms: The significance of depression. Brain Injury, 32(5), 583-592. doi: 10.1080/02699052.2018.1432894
Groves, S. J., Pitcher, T. L., Melzer, T. R., Jordan, J., Carter, J. D., Malhi, G. S., … Porter, R. J. (2018). Brain activation during processing of genuine facial emotion in depression: Preliminary findings. Journal of Affective Disorders, 225, 91-96. doi: 10.1016/j.jad.2017.07.049
Journal - Research Other
Almuqbel, M. M., Leeper, G., Palmer, D. N., Mitchell, N. L., Russell, K. N., Keenan, R. J., & Melzer, T. (2018). Practical implications of motion correction with motion insensitive radial k-space acquisitions in MRI. British Journal of Radiology, 91(1087), 20170593. doi: 10.1259/bjr.20170593
Almuqbel, M. M., Leeper, G. J., Petelo, J. F., Page, T. J., & Melzer, T. R. (2018). MRI artefact in the rectum caused by ingested orthodontic brackets. Radiography, 24(2), e48-e50. doi: 10.1016/j.radi.2017.10.002
Conference Contribution - Published proceedings: Abstract
Melzer, T., Myall, D., Livingston, L., Almuqbel, M., MacAskill, M., Pitcher, T., Horne, K., Grenfell, S., … Keenan, R., Dalrymple-Alford, J., & Anderson, T. (2018). Longitudinal MRI to predict cognitive impairment in Parkinson's disease. Movement Disorders, 33(Suppl. 2), (pp. S701). doi: 10.1002/mds.116
Melzer, T., Stark, M., Myall, D., Keenan, R., Livingston, L., Almuqbel, M., MacAskill, M., Pitcher, T., Horne, K., Grenfell, S., … Dalrymple-Alford, J., & Anderson, T. (2018). Amyloid PET and cognition in Parkinson's disease. Movement Disorders, 33(Suppl. 2), (pp. S698). doi: 10.1002/mds.116
MacAskill, M., Myall, D., Pitcher, T., Melzer, T., Dalrymple-Alford, J., & Anderson, T. (2018). Does having more children really delay Parkinson's age of onset in women? Movement Disorders, 33(Suppl. 2), (pp. S356). doi: 10.1002/mds.116
Pascoe, M., Melzer, T., Horwood, L. J., & Darlow, B. A. (2018). Very low birthweight young adults: Grey matter (GM) volume and perfusion, white matter (WM) integrity and the influence of birthweight. Journal of Paediatrics & Child Health, 54(Suppl. 1), (pp. 99-100). doi: 10.1111/jpc.13881
Castellazzi, G., Debernard, L., Melzer, T. R., Dalrymple-Alford, J. C., D'Angelo, E., Miller, D. H., Mason, D. F., & Gandini Wheeler-Kingshott, C. A. (2018). Functional connectome analysis reveals different alterations between relapsing remitting multiple sclerosis with short and longer disease duration. Multiple Sclerosis, 24(Suppl. 2), (pp. 622-623). doi: 10.1177/1352458518798591
David, T., Mathias, E., & Melzer, T. (2018). Integrated models of neurovascular coupling and BOLD signals. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 75). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr
Muller, S. C., Melzer, T. R., & Theys, C. (2018). Patterns of brain activation during overt speech production in adults with persistent developmental stuttering. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 35). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr
Theys, C., Melzer, T., de Vos, M., & Guenther, F. (2018). The neural basis of stuttering: Where and when do differences in brain activation occur? In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 34). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr
Pascoe, M., Melzer, T., Horwood, L. J., & Darlow, B. (2018). Adults born with very-low-birth-weight demonstrate alterations in grey matter volume, perfusion, and white matter integrity. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 71). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr
Livingstone, M., Elias, B., Goh, J., Peterson, E., Goulden, M., Myall, D., Melzer, T., Pitcher, T., Livingston, L., Horne, K., … Wilkinson, M., MacAskill, M., … Mulligan, H., Anderson, T., Hale, L., … Dalrymple-Alford, J. (2018). Theory of mind in Parkinson's disease: A longitudinal follow-up. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 55). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr
Elias, B., Livingstone, M., Irish, M., Nicolson, M., Peterson, E., Goulden, M., … Myall, D., Melzer, T., Pitcher, T., Livingston, L., Grenfell, S., … Wilkinson, M., Horne, K., MacAskill, M., … Mulligan, H., Anderson, T., Hale, L., & Dalrymple-Alford, J. (2018). Autobiographical memory in Parkinson's disease. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 45). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr
Conference Contribution - Verbal presentation and other Conference outputs
Mitchell, N. L., Russell, K. N., Wellby, M. P., Wicky, H. E., Schoderboeck, L., Barrell, G. K., Melzer, T. R., … Hughes, S. M., & Palmer, D. N. (2018, August). Efficacy of gene therapy in a sheep model of CLN5 Batten disease. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2017
Journal - Research Article
Lean, R. E., Melzer, T. R., Bora, S., Watts, R., & Woodward, L. J. (2017). Attention and regional gray matter development in very preterm children at age 12 years. Journal of the International Neuropsychological Society, 23(7), 539-550. doi: 10.1017/S1355617717000388
Conference Contribution - Published proceedings: Abstract
Horne, K.-L., Myall, D., MacAskill, M., Livingston, L., Grenfell, S., Melzer, T., Pitcher, T., Anderson, T., & Dalrymple-Alford, J. (2017). Patient-reported hallucinations and the probability of progression to dementia in Parkinson’s disease. Movement Disorders, 32(Suppl. 2), (pp. S373). doi: 10.1002/mds.27086
Jay, S., Melzer, T., & Snell, D. (2017). Chronic pain and advanced MRI techniques. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 36-37). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html
Livingstone, M., Elias, B., Goh, J., Peterson, E., Wilkinson, M., Goulden, M., … Melzer, T., Pitcher, T., Livingston, L., Horne, K., … MacAskill, M., … Mulligan, H., Cutfield, N., Anderson, T., Hale, L., & Dalrymple-Alford, J. (2017). Maintaining independence in Parkinson's disease: Cognitive effects of a combined cognitive and physical exercise intervention. In B. Leitch (Ed.), Proceedings of the 35th International Australasian Winter Conference on Brain Research. (pp. 62). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr/index.html
Peterson, E., Goh, J., Wilkinson, M., Livingstone, M., Elias, B., Goulden, M., Myall, D., Melzer, T., Pitcher, T., Livingston, L., Horne, K., Grenfell, S., … MacAskill, M., … Mulligan, H., Cutfield, N., Anderson, T., Hale, L., & Dalrymple-Alford, J. (2017). Motor outcomes in Parkinson's disease patients: An RCT of physical exercise and cognitive enrichment. In B. Leitch (Ed.), Proceedings of the 35th International Australasian Winter Conference on Brain Research. (pp. 62). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr/index.html
Elias, B., Goh, J., Peterson, E., Livingstone, M., Goulden, M., Myall, D., Melzer, T., Pitcher, T., Livingston, L., Horne, K., Grenfell, S., … Wilkinson, M., MacAskill, M., … Mulligan, H., Cutfield, N., Anderson, T., Hale, L., & Dalrymple-Alford, J. (2017). Theory of mind in Parkinson's disease: Improvement after physical and cognitive exercise. In B. Leitch (Ed.), Proceedings of the 35th International Australasian Winter Conference on Brain Research. (pp. 61). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr/index.html
Stark, M. R., Melzer, T. R., Keenan, R. J., Myall, D. J., Kaur, G., Livingston, L., Horne, K., … MacAskill, M. R., Dalrymple-Alford, J. C., & Anderson, T. J. (2017). Parkinson's disease: No association between amyloid PET imaging and cognitive status. In B. Leitch (Ed.), Proceedings of the 35th International Australasian Winter Conference on Brain Research. (pp. 52). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr/index.html
Horne, K.-L., Myall, D. J., MacAskill, M. R., Livingston, L., Grenfell, S. F., Melzer, T. R., Pitcher, T. L., Anderson, T. J., & Dalrymple-Alford, J. C. (2017). Patient-reported hallucinations are associated with future progression to dementia in Parkinson's disease, but cognition is more informative. In B. Leitch (Ed.), Proceedings of the 35th International Australasian Winter Conference on Brain Research. 35, (pp. 40). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr/index.html
Conference Contribution - Poster Presentation (not in published proceedings)
Russell, K. N., Mitchell, N. L., Wellby, M. P., Melzer, T. R., Barrell, G. K., & Palmer, D. N. (2017, September). Longitudinal in vivo monitoring of disease progression and viral mediated gene injection therapy in ovine Batten disease. Poster session presented at the 21st European Study Group on Lysosomal Diseases (ESGLD) Workshop, Lyon, France.
Conference Contribution - Verbal presentation and other Conference outputs
Pascoe, M., Melzer, T., Darlow, B., & Horwood, J. (2017, November). Young adults born with very low birthweight: Grey matter volume and perfusion, WM integrity and the influence of birthweight. Verbal presentation at the Paediatric Society of New Zealand 69th Annual Scientific Meeting, Christchurch, New Zealand.
2016
Journal - Research Article
Wood, K.-L., Myall, D. J., Livingston, L., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., … Anderson, T. J., & Dalrymple-Alford, J. C. (2016). Different PD-MCI criteria and risk of dementia in Parkinson's disease: A 4-year longitudinal study. npj Parkinson's Disease, 2, 15027. doi: 10.1038/npjparkd.2015.27
Almuqbel, M., Melzer, T. R., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Wood, K.-L., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson’s disease in a clinical setting. Parkinsonism & Related Disorders, 22, 54-61. doi: 10.1016/j.parkreldis.2015.11.008
Conference Contribution - Published proceedings: Abstract
Tippett, L., Melzer, T., Ilse, C., & Williams, J. (2016). Introduction to Brain Research New Zealand - Dementia Prevention Research Clinics. Neuroepidemiology, 47(3-4), (pp. 129-130). doi: 10.1159/000453097
Innes, C., Poudel, G., Kelly, P., Hlavac, M., Melzer, T., & Jones, R. (2016). Previous and current research at the New Zealand Brain Research Institute: Impact of sleep restriction and obstructive sleep apnoea on cerebral perfusion. Journal of Sleep Research, 25(Suppl. 2), (pp. 64). doi: 10.1111/jsr.12453
Snell, D., Martin, R., Surgenor, L., Hay-Smith, J., Hooper, G., Melzer, T., Siegert, R., & Anderson, T. (2016). Mild traumatic brain injury and chronic pain: Using mixed methods to explore unique and overlapping phenomenology. Archives of Physical Medicine & Rehabilitation, 97(10), (pp. e2-e3). doi: 10.1016/j.apmr.2016.08.004
Melzer, T. R., Keenan, R. J., Myall, D. J., Kaur, G., Livingston, L., Horne, K., Marsh, S., MacAskill, M. R., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Amyloid imaging and cognition in Parkinson’s disease: Interim report. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 72). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Horne, K., Myall, D. J., Livingston, L., Grenfell, S. F., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., Anderson, T. J., & Dalrymple-Alford, J. C. (2016). Risk of dementia in Parkinson’s disease: Towards optimal short cognitive testing. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 61). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Pitcher, T. L., Wood, K., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Tracking Parkinson's disease over 2-6 years with MRI. Movement Disorders, 31(Suppl. 2), (pp. S427). doi: 10.1002/mds.26688
Almuqbel, M. M., Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Wood, K., Pitcher, T. L., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Corticol atrophy in cognitively impaired Parkinson's disease patients. Movement Disorders, 31(Suppl. 2), (pp. S397). doi: 10.1002/mds.26688
Kaur, G., Keenan, R. J., Marsh, S., Myall, D. J., Livingston, L., Dalrymple-Alford, J. C., Anderson, T. J., & Melzer, T. R. (2016). Amyloid imaging for cognitive impairment in Parkinson’s disease. New Zealand Medical Journal, 129(1439), (pp. 90). Retrieved from http://www.nzma.org.nz/journal
Stark, M., Keenan, R. J., Marsh, S., Myall, D. J., Livingston, L., Dalrymple-Alford, J. C., Anderson, T. J., & Melzer, T. R. (2016). Cognitive impairment in Parkinson’s disease: A study of early-phase amyloid PET and arterial spin labeling perfusion MRI. New Zealand Medical Journal, 129(1439), (pp. 89). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Poster Presentation (not in published proceedings)
Almuqbel, M., Melzer, T., Myall, D., MacAskill, M., Livingston, L., Wood, K., Pitcher, T., Keenan, R., Dalrymple-Alford, J., & Anderson, T. (2016, June). Regional cortical thinning is associated with cognitive decline in Parkinson's disease. Poster session presented at the 22nd Annual Meeting of the Organization for Human Brain Mapping (OHBM), Geneva, Switzerland.
Conference Contribution - Verbal presentation and other Conference outputs
Mitchell, N. L., Barrell, G. K., Russell, K. N., Wellby, M. P., Melzer, T. R., Wicky, H. E., Hughes, S. M., … Palmer, D. N. (2016, October). Gene transfer can prevent stereotypical disease development in ovine CLN5 and CLN6 models of NCL. Verbal presentation at the 15th International Conference on Neuronal Ceroid Lipofuscinosis (Batten Disease), Boston, USA.
Mitchell, N. L., Barrell, G. K., Russell, K. N., Wellby, M. P., Melzer, T. R., Wicky, H. E., Hughes, S. M., … Palmer, D. N. (2016, November). In vivo efficacy of viral-mediated gene transfer in ovine Batten disease. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society (NZMS) and the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB), Christchurch, New Zealand.
Mitchell, N. L., Barrell, G. K., Russell, K. N., Wellby, M., Melzer, T. R., Wicky, H. E., Hughes, S. M., … Palmer, D. N. (2016, August). Viral-mediated gene transfer prevents stereotypical disease development in ovine Batten disease. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
Other Research Output
Melzer, T. (2016, March). Brain imagining in Parkinson's disease. Public Health Lecture Series, University of Otago, Christchurch, New Zealand. [Public Seminar].
2015
Journal - Research Article
Melzer, T. R., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Watts, R., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2015). Tracking Parkinson's disease over one year with multimodal magnetic resonance imaging in a group of older patients with moderate disease. PLoS ONE, 10(12), e0143923. doi: 10.1371/journal.pone.0143923
Debernard, L., Melzer, T. R., Alla, S., Eagle, J., Van Stockum, S., Graham, C., Osborne, J. R., Dalrymple-Alford, J. C., Miller, D. H., & Mason, D. F. (2015). Deep grey matter MRI abnormalities and cognitive function in relapsing-remitting multiple sclerosis. Psychiatry Research: Neuroimaging, 234(3), 352-361. doi: 10.1016/j.pscychresns.2015.10.004
Innes, C. R. H., Kelly, P. T., Hlavac, M., Melzer, T. R., & Jones, R. D. (2015). Decreased regional cerebral perfusion in moderate-severe obstructive sleep apnoea during wakefulness. Sleep, 38(5), 699-706. doi: 10.5665/sleep.4658
Journal - Research Other
Darlow, B. A., Horwood, L. J., Woodward, L. J., Elliott, J. M., Troughton, R. W., Elder, M. J., Epton, M. J., Stanton, J. D., Swanney, M. P., Keenan, R., Melzer, T. R., McKelvey, V. A., Levin, K., Meeks, M. G., Espiner, E. A., Cameron, V. A., & Martin, J. (2015). The New Zealand 1986 very low birth weight cohort as young adults: Mapping the road ahead. BMC Pediatrics, 15, 90. doi: 10.1186/s12887-015-0413-9
Conference Contribution - Published proceedings: Abstract
Wood, K., Livingston, L., Myall, D. J., Grenfell, S., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., & Dalrymple-Alford, J. C. (2015). Neuropsychiatric status and different MCI criteria in Parkinson's disease. In B. Leitch (Ed.), Proceedings of the 33rd International Australasian Winter Conference on Brain Research. (pp. 37). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Castellazzi, G., Debernard, L., Melzer, T. R., Dalrymple-Alford, J. C., D'Angelo, E. U., Miller, D. H., … Mason, D. F. (2015). Functional connectivity impairment shows distinct sensory and cognitive patterns in relapsing remitting multiple sclerosis with different disease duration. Multiple Sclerosis Journal, 23(11, Suppl.), (pp. 11-12). doi: 10.1177/1352458515602640
Wood, K.-L., Myall, D. J., Livingston, L., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., … Anderson, T. J., & Dalrymple-Alford, J. C. (2015). Progression to dementia in Parkinson's disease over four-years: Risk with alternative MCI criteria. New Zealand Medical Journal, 128(1421). Retrieved from https://www.nzma.org.nz/journal
Innes, C., Kelly, P., Hlavac, M., Melzer, T., & Jones, R. (2015). Decreased regional cerebral perfusion in moderate-severe obstructive sleep apnoea during wakefulness. Australasian Physical & Engineering Sciences in Medicine, 38(1), (pp. 186-187). doi: 10.1007/s13246-014-0324-3
Almuqbel, M., Melzer, T., Myall, D., MacAskill, M., Livingston, L., Wood, K., Pitcher, T., Keenan, R., Dalrymple-Alford, J., & Anderson, T. (2015). Longitudinal magnetic resonance spectroscopy and cognitive impairment in Parkinson's disease. Proceedings of the Organization for Human Brain Mapping (OHBM) 21st Annual Meeting. 1902. Retrieved from http://www.humanbrainmapping.org
Melzer, T., Myall, D., Livingston, L., Wood, K., Pitcher, T., Watts, R., Keenan, R., MacAskill, M., Dalrymple-Alford, J., & Anderson, T. (2015). White matter lesions contribute to future dementia in Parkinson's disease. Proceedings of the Organization for Human Brain Mapping (OHBM) 21st Annual Meeting. 1167. Retrieved from http://www.humanbrainmapping.org
Myall, D. J., Wood, K.-L., Livingston, L., Pitcher, T. L., Melzer, T. R., MacAskill, M. R., Anderson, T. J., & Dalrymple-Alford, J. C. (2015). Individualised medicine using an abbreviated cognitive screen for dementia prediction in Parkinson's disease. Movement Disorders, 30(Suppl. 1), (pp. S346). doi: 10.1002/mds.26295
Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Pitcher, T. L., Watts, R., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2015). Multimodal MRI changes in Parkinson's disease over one year. Movement Disorders, 30(Suppl. 1), (pp. S18-S19). doi: 10.1002/mds.26295
Conference Contribution - Verbal presentation and other Conference outputs
Snell, D. L., Martin, R., Macleod, A. D., Surgenor, L., Siegert, R. J., Hay-Smith, E. J. C., Hooper, G. J., Melzer, T., & Anderson, T. (2015, October). Untangling symptoms: Postconcussion syndrome or chronic pain? Verbal presentation at the Australasian Faculty of Rehabilitation Medicine and the New Zealand Rehabilitation Association (AFRM/NZRA) Combined Rehabilitation Meeting, Wellington, New Zealand.
2014
Journal - Research Article
Debernard, L., Melzer, T. R., Van Stockum, S., Graham, C., Wheeler-Kingshott, C. A. M., Dalrymple-Alford, J. C., Miller, D. H., & Mason, D. F. (2014). Reduced grey matter perfusion without volume loss in early relapsing-remitting multiple sclerosis. Journal of Neurology, Neurosurgery & Psychiatry, 86(5), 544-551. doi: 10.1136/jnnp-2013-305612
Le Heron, C. J., Wright, S. L., Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Keenan, R. J., … Dalrymple-Alford, J. C., & Anderson, T. J. (2014). Comparing cerebral perfusion in Alzheimer's disease and Parkinson's disease dementia: An ASL-MRI study. Journal of Cerebral Blood Flow & Metabolism, 34, 964-970. doi: 10.1038/jcbfm.2014.40
Conference Contribution - Published proceedings: Abstract
Innes, C., Kelly, P., Hlavac, M., Melzer, T., & Jones, R. (2014). Decreased regional cerebral perfusion in moderate-severe obstructive sleep apnoea during wakefulness. Proceedings of the Annual Conference of the New Zealand Branch of the Australasian College of Physical Scientists and Engineers in Medicine (NZPEM). (pp. 41-42). Retrieved from http://nzpem.org.nz/wordpress/?page_id=11
Wood, K.-L., Livingston, L., Myall, D. J., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., Anderson, T. J., & Dalrymple-Alford, J. C. (2014). Alternative criteria for mild cognitive impairment in Parkinson's disease: Relevance to dementia onset. Movement Disorders, 29(Suppl. 1), (pp. S371). doi: 10.1002/mds.25914
Le Heron, C. J., Wright, S. L., Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Keenan, R. J., … Dalrymple-Alford, J. C., & Anderson, T. J. (2014). Comparing cerebral perfusion in Alzheimer's disease and Parkinson's disease dementia: An ASL-MRI study. Movement Disorders, 29(Suppl. 1), (pp. S351-S352). doi: 10.1002/mds.25914
Myall, D. J., Wood, K., Livingston, L., Pitcher, T. L., Melzer, T. R., MacAskill, M. R., Anderson, T. J., & Dalrymple-Alford, J. C. (2014). Individualised medicine: Predicting dementia in Parkinson's disease. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 32nd International Australasian Winter Conference on Brain Research. 32, (pp. 73). AWCBR. Retrieved from https://web.psy.otago.ac.nz/awcbr/proceedings.html
Almuqbel, M., Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Wood, K.-L., Pitcher, T. L., Dalrymple-Alford, J. C., & Anderson, T. J. (2014). Cognitive status in Parkinson's disease characterized by magnetic resonance spectroscopy. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 32nd International Australasian Winter Conference on Brain Research. 32, (pp. 56). AWCBR. Retrieved from https://web.psy.otago.ac.nz/awcbr/proceedings.html
Wood, K., Myall, D. J., Livingston, L., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., Anderson, T. J., & Dalrymple-Alford, J. C. (2014). Comparing mild cognitive impairment criteria in Parkinson's disease: Influence on dementia onset. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 32nd International Australasian Winter Conference on Brain Research. 32, (pp. 41). AWCBR. Retrieved from https://web.psy.otago.ac.nz/awcbr/proceedings.html
Melzer, T. R., Myall, D. J., Livingston, L., Wood, K.-L., Pitcher, T. L., Keenan, R. J., MacAskill, M. R., Dalrymple-Alford, J. C., & Anderson, T. J. (2014). White matter lesions: A factor in developing dementia in patients with Parkinson's disease. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 32nd International Australasian Winter Conference on Brain Research. 32, (pp. 34). AWCBR. Retrieved from https://web.psy.otago.ac.nz/awcbr/proceedings.html
Almuqbel, M., Melzer, T. R., Myall, D., MacAskill, M., Livingston, L., Pitcher, T., Dalrymple-Alford, J., & Anderson, T. (2014). Magnetic Resonance Spectroscopy: A potential marker for cognitive impairment in Parkinson’s disease. New Zealand Medical Journal, 127(1396). Retrieved from http://www.nzma.org.nz/journal
2013
Journal - Research Article
Macrae, P. R., Jones, R. D., Myall, D. J., Melzer, T. R., & Huckabee, M.-L. (2013). Cross-sectional area of the anterior belly of the digastric muscle: Comparison of MRI and ultrasound measures. Dysphagia, 28(3), 375-380. doi: 10.1007/s00455-012-9443-8
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Livingston, L., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2013). White matter microstructure deteriorates across cognitive stages in Parkinson disease. Neurology, 80(8), 1841-1849. doi: 10.1212/WNL.0b013e3182929f62
Journal - Research Other
Melzer, T. R. (2013). The evolution of diffusion tensor imaging in Parkinson's disease research. Movement Disorders, 28(9), 1316. doi: 10.1002/mds.25566
Conference Contribution - Published proceedings: Abstract
Dalrymple-Alford, J. C., McCurrie, C. H., Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Keenan, R., Anderson, T. J., & Livingston, L. (2013). Domain specific cognitive dysfunction in Parkinson's and associated pattern of grey atrophy. Movement Disorders, 28(Suppl. 1), (pp. S202-S203). doi: 10.1002/mds.25605
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Livingston, L., Keenan, R., Dalrymple-Alford, J. C., & Anderson, T. J. (2013). Serial DTI and cognitive decline in Parkinson's disease. Movement Disorders, 28(Suppl. 1), (pp. S197-S198). doi: 10.1002/mds.25605
Debernard, L., Melzer, T., van Stockum, S., Graham, C., Dalrymple-Alford, J., Miller, D. H., & Mason, D. (2013). Volumetric, diffusion and perfusion imaging of grey matter in early relapsing remitting multiple sclerosis. Multiple Sclerosis Journal, 19(11, Suppl. 1), (pp. 414). doi: 10.1177/1352458513502429
Debernard, L., Alla, S., Melzer, T., van Stockum, S., Graham, C., Dalrymple-Alford, J., … Mason, D. (2013). Cortical perfusion is associated with cognitive function in relapsing remitting multiple sclerosis patients. Multiple Sclerosis Journal, 19(11, Suppl. 1), (pp. 171). doi: 10.1177/1352458513502429
Wood, K., Livingston, L., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., Anderson, T. J., & Dalrymple-Alford, J. C. (2013). Criteria for Parkinson's disease with mild cognitive impairment associated with increased progression to dementia. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 31st International Australasian Winter Conference on Brain Research. 31, (pp. 58). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2013copy.html
Debernard, L., Melzer, T. R., van Stockum, S., Graham, C., Dalrymple-Alford, J. C., Wheeler-Kingshott, C., Miller, D. H., & Mason, D. F. (2013). Grey matter hypoperfusion occurs in the presence of preserved grey matter structural integrity in early relapsing-remitting multiple sclerosis patients. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 31st International Australasian Winter Conference on Brain Research. 31, (pp. 55). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2013copy.html
Grenfell, S., Melzer, T. R., Young, B., Wang, A., Livingston, L., Keenan, R. J., MacAskill, M. R., Anderson, T. J., & Dalrymple-Alford, J. C. (2013). Reduced default mode network connectivity and autobiographical memory in mild cognitive impairment. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 31st International Australasian Winter Conference on Brain Research. 31, (pp. 47). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2013copy.html
Dalrymple-Alford, J. C., Livingston, L., Melzer, T. R., Wood, K., Goh, T. J., Pitcher, T. L., Graham, C. F., Keenan, R. J., MacAskill, M. R., & Anderson, T. J. (2013). Current perspectives on Parkinson's disease: Cognition to the fore. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 31st International Australasian Winter Conference on Brain Research. 31, (pp. 29). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2013copy.html
Feng, S. D. W., MacAskill, M. R., Pitcher, T. L., Melzer, T. R., Graham, C. F., Dalrymple-Alford, J. C., & Anderson, T. J. (2013). ASL derived perfusion network shows correlation with saccadic eye movement measures in Parkinson's disease. New Zealand Medical Journal, 126(1375). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Poster Presentation (not in published proceedings)
Melzer, T., Watts, R., MacAskill, M., Pitcher, T., Livingston, L., Keenan, R., Dalrymple-Alford, J., & Anderson, T. (2013, June). Longitudinal microstructural change is related to cognitive decline in Parkinson's disease. Poster session presented at the Organization for Human Brain Mapping (OHBM) 19th Annual Meeting, Seattle, WA.
Debernard, L., Melzer, T., Van Stockum, S., Eagle, J., Graham, C., Myall, D., … Miller, D., & Mason, D. (2013, June). Extensive GM perfusion abnormalities but preserved GM volume in early relapsing-remitting MS. Poster session presented at the Organization for Human Brain Mapping (OHBM) 19th Annual Meeting, Seattle, WA.
Debernard, L., Melzer, T., Van Stockum, S., Eagle, J., Graham, C., Dalrymple-Alford, J., Miller, D., & Mason, D. (2013, June). Evidence for deep GM perfusion abnormalities, prior to neuronal loss in relapsing-remitting MS. Poster session presented at the Organization for Human Brain Mapping (OHBM) 19th Annual Meeting, Seattle, WA.
2012
Journal - Research Article
Pitcher, T. L., Melzer, T. R., MacAskill, M. R., Graham, C. F., Livingston, L., Keenan, R. J., … Dalrymple-Alford, J. C., & Anderson, T. J. (2012). Reduced striatal volumes in Parkinson's disease: A magnetic resonance imaging study. Translational Neurodegeneration, 1(1), 17. doi: 10.1186/2047-9158-1-17
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Livingston, L., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2012). Grey matter atrophy in cognitively impaired Parkinson's disease. Journal of Neurology, Neurosurgery & Psychiatry, 83, 188-194. doi: 10.1136/jnnp-2011-300828
Conference Contribution - Published proceedings: Abstract
Melzer, T. R., Myall, D. J., Watts, R., MacAskill, M. R., Pitcher, T. L., Keenan, R., Livingston, L., Dalrymple-Alford, J. C., & Anderson, T. J. (2012). MRI brain integrity and perfusion measures in Parkinson's disease: Prediction and progression. Movement Disorders, 27(Suppl. 1), (pp. S26-S27). doi: 10.1002/mds.25051
Borlase, N. M., Melzer, T., Livingston, L., Watts, R., Keenan, R., Anderson, T. J., & Dalrymple-Alford, J. C. (2012). Thalamo-cortical circuitry in mild cognitive impairment and dementia in Parkinson's disease: Combined diffusion tensor and fiber tractography study. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 30th International Australasian Winter Conference on Brain Research. 30, (pp. 27). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2012.html
2011
Journal - Research Article
Innes, C. R. H., Lee, D., Chen, C., Ponder-Sutton, A. M., Melzer, T. R., & Jones, R. D. (2011). Do complex models increase prediction of complex behaviours? Predicting driving ability in people with brain disorders. Quarterly Journal of Experimental Psychology, 64(9), 1714-1725. doi: 10.1080/17470218.2011.555821
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J. F., Rüeger, S., Pitcher, T. L., Livingston, L., Graham, C., Keenan, R., … Dalrymple-Alford, J. C., & Anderson, T. J. (2011). Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson's disease. Brain, 134(3), 845-855. doi: 10.1093/brain/awq377
Dalrymple-Alford, J. C., Livingston, L., MacAskill, M. R., Graham, C., Melzer, T. R., Porter, R. J., … Anderson, T. J. (2011). Characterizing mild cognitive impairment in Parkinson's disease. Movement Disorders, 26(4), 629-636. doi: 10.1002/mds.23592
Conference Contribution - Published proceedings: Abstract
Feng, S. D. W., MacAskill, M. R., Pitcher, T. L., Melzer, T. R., & Anderson, T. J. (2011). Correlations between ASL blood flow MRI and eye movement abnormalities in Parkinson's disease. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 7.5. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html
Borlase, N. M., Melzer, T., Watts, R., Livingston, L., Graham, C., Pitcher, T., MacAskill, M., Keenan, R., Anderson, T. J., & Dalrymple-Alford, J. C. (2011). Diffusion tensor imaging in the thalamus: An advanced method used to investigate cognitive decline in Parkinson's disease. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 2.2. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Keenan, R., Livingston, L., Dalrymple-Alford, J. C., & Anderson, T. J. (2011). Decreasing structural integrity with cognitive impairment in Parkinson's disease. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 2.1. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html
Awarded Doctoral Degree
Melzer, T. R. (2011). Magnetic resonance imaging of cognition in Parkinson's disease (PhD). University of Otago, Christchurch, New Zealand. 185p.
2010
Journal - Research Article
Dalrymple-Alford, J. C., MacAskill, M. R., Nakas, C. T., Livingston, L., Graham, C., Crucian, G. P., Melzer, T. R., … Keenan, R., Wells, S., Porter, R. J., … Anderson, T. J. (2010). The MoCA: Well-suited screen for cognitive impairment in Parkinson disease. Neurology, 75(19), 1717-1725. doi: 10.1212/WNL.0b013e3181fc29c9
Conference Contribution - Published proceedings: Abstract
Melzer, T. R., Watts, R., MacAskill, M., Keenan, R., Shankaranarayanan, A., Alsop, D. C., Graham, C., Livingston, L., Dalrymple-Alford, J. C., & Anderson, T. J. (2010). Perfusion networks in Parkinson's disease revealed using arterial spin labeling. Proceedings of the Joint Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM) & European Society for Magnetic Resonance in Medicine and Biology (ESMRMB). Retrieved from http://www.ismrm.org/meetings-workshops/2010-annual-meeting-3/
Borlase, N., Melzer, T., Watts, R., Livingston, L., Graham, C., Pitcher, T., … Keenan, R., Anderson, T., & Dalrymple-Alford, J. (2010). Diffusion tensor imaging and fibre tracking applied to the thalamus: A new approach to understanding Parkinson's disease. In B. Leitch (Ed.), Proceedings of the 28th International Australasian Winter Conference on Brain Research. 28, (pp. 54). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2010.htm
Feng, S. D. W., MacAskill, M. R., Pitcher, T. L., Melzer, T. R., Pearson, J. F., Graham, C., & Anderson, T. J. (2010). Correlations between ASL blood flow MRI and eye movement abnormalities in Parkinson's disease. In B. Leitch (Ed.), Proceedings of the 28th International Australasian Winter Conference on Brain Research. 28, (pp. 52). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2010.htm
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J. F., Keenan, R., Shankaranarayanan, A., … Graham, C., Livingston, L., Dalrymple-Alford, J. C., & Anderson, T. J. (2010). Reduced cerebral perfusion in cognitively impaired Parkinson's disease. In B. Leitch (Ed.), Proceedings of the 28th International Australasian Winter Conference on Brain Research. 28, (pp. 53). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2010.htm
Dalrymple-Alford, J. C., MacAskill, M. R., Nakas, C. T., Livingston, L., Wang, Y. C., Graham, C. F., Melzer, T., … Anderson, T. J. (2010). Parkinson's disease and cognition: Clarifying the spectrum of impairments. In B. Leitch (Ed.), Proceedings of the 28th International Australasian Winter Conference on Brain Research. 28, (pp. 52). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2010.htm
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J., Livingston, L., Graham, C., Keenan, R., … Dalrymple-Alford, J. C., & Anderson, T. J. (2010). Characteristic arterial spin labeling MRI perfusion abnormalities in early, treatment-free Parkinson's disease. New Zealand Medical Journal, 123(1313). Retrieved from http://journal.nzma.org.nz/journal/123-1313/4096/content.pdf
Conference Contribution - Poster Presentation (not in published proceedings)
Melzer, T. R., Watts, R., MacAskill, M. R., Keenan, R., Shankaranarayanan, A., Alsop, D. C., Graham, C., Livingston, L., Dalrymple-Alford, J. C., & Anderson, T. J. (2010, September). Can advanced Magnetic Resonance Imaging (MRI) help characterize cognitive and motor impairments in Parkinson's disease? Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand.
2009
Conference Contribution - Published proceedings: Abstract
Melzer, T. R., Watts, R., MacAskill, M. R., Keenan, R., Shankaranarayanan, A., Alsop, D. C., Graham, C., Livingston, L., … Anderson, T. J. (2009). Multimodal magnetic resonance imaging of the posterior cingulate in Parkinson's disease. In R. Napper (Ed.), Proceedings of the 27th International Australasian Winter Conference on Brain Research. 27, (pp. 67). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2009.htm
Pitcher, T. L., Dalrymple-Alford, J. C., Livingston, L., MacAskill, M. R., Melzer, T. R., Watts, R., & Anderson, T. J. (2009). MRI volumetric analysis of the putamen and caudate nucleus in Parkinson's disease. In R. Napper (Ed.), Proceedings of the 27th International Australasian Winter Conference on Brain Research. 27, (pp. 45). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2009.htm
Livingston, L., Graham, C. F., Melzer, T., Crucian, G., MacAskill, M. R., Watts, R., Anderson, T. J., & Dalrymple-Alford, J. C. (2009). Characterizing mild cognitive impairment in Parkinson's disease. In R. Napper (Ed.), Proceedings of the 27th International Australasian Winter Conference on Brain Research. 27, (pp. 46). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2009.htm
Chirackal, V. V., Livingston, L., Graham, C. F., Melzer, T., Crucian, G. P., MacAskill, M. R., … Anderson, T. J., & Dalrymple-Alford, J. C. (2009). Instrumental activities of daily living in cognitively impaired and unimpaired Parkinson's disease patients. In R. Napper (Ed.), Proceedings of the 27th International Australasian Winter Conference on Brain Research. 27, (pp. 66). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2009.htm
Wright, S. L., MacAskill, M. R., Watts, R., Melzer, T. R., Keenan, R., Shankaranarayanan, A., … Anderson, T. J. (2009). Cerebral blood flow perfusion patterns in Alzheimer's Disease using MRI arterial spin labeling: An initial study. Journal of Clinical Neuroscience. 16(11), (pp. 1528). doi: 10.1016/j.jocn.2009.07.039
Wright, S., MacAskill, M., Watts, R., Melzer, T., Keenan, A. J., Shankaranarayanan, A., … Anderson, T. (2009). Arterial spin-labeling magnetic resonance imaging in the identification of cerebral perfusion patterns in alzheimer's disease: An initial study. Alzheimer's and Dementia. 5(5), (pp. e17). [Abstract]
2008
Journal - Research Article
Melzer, T. R., Cook, N. J., Butler, A. P., Watts, R., Anderson, N., Tipples, R., & Butler, P. H. (2008). Spectroscopic biomedical imaging with the Medipix2 detector. Australasian Physical & Engineering Sciences in Medicine, 31(4), 300-306.
Butler, A. P. H., Anderson, N. G., Tipples, R., Cook, N., Watts, R., Meyer, J., … Melzer, T. R., & Butler, P. H. (2008). Bio-medical X-ray imaging with spectroscopic pixel detectors. Nuclear Instruments & Methods in Physics Research Section A, 591(1), 141-146. doi: 10.1016/j.nima.2008.03.039
Conference Contribution - Published proceedings: Abstract
Melzer, T., Butler, A. P., Cook, N. J., Watts, R., Anderson, N., Tipples, R., & Butler, P. H. (2008). Feasibility of spectroscopic biomedical imaging with Medipix2. Australasian Physical & Engineering Sciences in Medicine. 31(4), (pp. 442). [Abstract]
Melzer, T. R., Watts, R., MacAskill, M. R., Graham, C., Livingston, L., Dalrymple-Alford, J. C., & Anderson, T. J. (2008). Limbic system structural integrity and global cognitive status in Parkinson's disease: A DTI analysis. In J. G. Anson (Ed.), Proceedings of the 26th International Australasian Winter Conference on Brain Research. 26, (pp. 28). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2008Abstracts.pdf