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Contact Details

+64 3 479 5942
Department of Microbiology and Immunology
Research summary
Applied and molecular immunology, medical microbiology, vaccines


My research interest is infection and immunity. In particular, I am interested in mucosal associated invariant T (MAIT) cells, their role in antibacterial immunity, and how they might be harnessed to prevent or treat bacterial infection. I have been involved in several fundamental discoveries in MAIT cell biology.

I am also interested in the antimicrobial resistance, in particular its rapid detection, characterisation, and transmission, especially in Enterobacteriaceae.

My clinical specialty is medical microbiology.

For more detail see:


Ussher, J. E., Bilton, M., Attwod, E., Shadwell, J., Richardson, R., de Lara, C., … Willberg, C. B. (2014). CD161++CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner. European Journal of Immunology, 44(1), 195-203. doi: 10.1002/eji.201343509 Journal - Research Article

Cosgrove, C., Ussher, J. E., Rauch, A., Gärtner, K., Kurioka, A., Hühn, M. H., … Klenerman, P. (2013). Early and nonreversible decrease of CD161++/MAIT cells in HIV infection. Blood, 121(6), 951-961. doi: 10.1182/blood-2012-06-436436 Journal - Research Article

Sheppard, H. M., Ussher, J. E., Verdon, D., Chen, J., Taylor, J. A., & Dunbar, P. R. (2013). Recombinant adeno-associated virus serotype 6 efficiently transduces primary human melanocytes. PLoS ONE, 8(4), e62753. doi: 10.1371/journal.pone.0062753 Journal - Research Article

Locke, M., Ussher, J. E., Mistry, R., Taylor, J. A., & Dunbar, P. R. (2011). Transduction of human adipose-derived mesenchymal stem cells by recombinant adeno-associated virus vectors. Tissue Engineering Part C: Methods, 17(9), 949-959. doi: 10.1089/ten.tec.2011.0153 Journal - Research Article

Ussher, J. E., & Taylor, J. A. (2010). Optimized transduction of human monocyte-derived dendritic cells by recombinant adeno-associated virus serotype 6. Human Gene Therapy, 21(12), 1675-1686. doi: 10.1089/hum.2010.087 Journal - Research Article

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