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Associate Professor Khoon Lim

Contact Details

Email
khoon.lim@otago.ac.nz
Position
Adjunct Associate Professor
Department
Department of Orthopaedic Surgery and Musculoskeletal Medicine (Christchurch)
Research summary
Bioengineering; tissue regeneration

Research

Associate Professor Khoon Lim is a biomedical engineer with specialisation in polymer chemistry. His research focus is on using a class of polymers known as hydrogels as tissue engineering matrices for a variety of applications.

His research technology platform involves photo-polymerisable hydrogel bioinks for 3D bioprinting of functional tissues and also delivery of bioactive molecules to promote tissue regeneration.

Associate Professor Lim's research projects include:

  • Developing new bioinks for 3D Bioprinting of functional tissues
  • Hydrogels for smart delivery of growth factors to promote bone vascularisation
  • Engineering 3D cancer models for high-throughput drug screening
  • Delivery of brain derived growth factor for improved post-stroke recovery
  • Engineering silk as tissue engineering matrices.

Associate Professor Lim is currently an Associate Investigator on the Centre of Research Excellence in Medical Technologies (MedTech CoRE), Affiliate Investigator on the Maurice Wilkins Centre (MWC) for Molecular Diversity and Executive Committee member of the Australasian Society of Biomaterials and Tissue Engineering (ASBTE).

Publications

Major, G., Simcock, J., Kumar, A., Kleffmann, T., Woodfield, T. B. F., & Lim, K. S. (2023). Comprehensive matrisome profiling of human adipose tissue for soft tissue reconstruction. Advanced Biology. Advance online publication. doi: 10.1002/adbi.202300448

Longoni, A., Major, G. S., Jiang, S., Farrugia, B. L., Kieser, D. C., Woodfield, T. B. F., … Lim, K. S. (2023). Pristine gelatin incorporation as a strategy to enhance the biofunctionality of poly(vinyl alcohol)-based hydrogels for tissue engineering applications. Biomaterials Science. Advance online publication. doi: 10.1039/d3bm01172k

Vahala, D., Amos, S. E., Sacchi, M., Soliman, B. G., Hepburn, M. S., Mowla, A., … Lim, K. S., & Choi, Y. S. (2023). 3D volumetric mechanosensation of MCF7 breast cancer spheroids in a linear stiffness gradient GelAGE. Advanced Healthcare Materials, 2301506. Advance online publication. doi: 10.1002/adhm.202301506

Major, G., Longoni, A., Simcock, J., Magon, N. J., Harte, J., Bathish, B., Kemp, R., Woodfield, T., & Lim, K. S. (2023). Clinical applicability of visible light-mediated cross-linking for structural soft tissue reconstruction. Advanced Science, 10, 2300538. doi: 10.1002/advs.202300538

Zou, Z., Li, H., Yu, K., Ma, K., Wang, Q., Tang, J., … Lim, K., Hooper, G., Woodfield, T., Cui, X., … Tian, K. (2023). The potential role of synovial cells in the progression and treatment of osteoarthritis. Exploration. Advance online publication. doi: 10.1002/EXP.20220132

Kieser, D., Soltani, S., Wyatt, M., Lim, K., & Kieser, S. (2020). Spontaneous spinal epidural haematomas. In B. Gürer (Ed.), Vascular malformations of the central nervous system. (pp. 103-111). London, UK: IntechOpen. doi: 10.1021/ic0482537

Chapter in Book - Research

Atienza Roca, P., Cui, X., Hooper, G. J., Woodfield, T. B. F., Lim, K. S., & Khang, G. (2018). Growth factor delivery systems for tissue engineering and regenerative medicine. In H. J. Chun, C. H. Park & I. K. Kwon (Eds.), Advances in experimental medicine and biology: (Vol. 1078) Cutting-edge enabling technologies for regenerative medicine. (pp. 245-269). Singapore: Springer. doi: 10.1007/978-981-13-0950-2_13

Chapter in Book - Research

Lim, K. S., Martens, P., & Poole-Warren, L. (2018). Biosynthetic hydrogels for cell encapsulation. In J. Li, Y. Osada & J. Cooper-White (Eds.), Functional hydrogels as biomaterials. (pp. 1-29). Berlin, Germany: Springer. doi: 10.1007/978-3-662-57511-6_1

Chapter in Book - Research

Woodfield, T., Lim, K., Morouço, P., Levato, R., Malda, J., & Melchels, F. (2017). Biofabrication in tissue engineering. In P. Ducheyne, D. W. Grainger, K. E. Healy, D. W. Hutmacher & C. J. Kirkpatrick (Eds.), Comprehensive biomaterials II: (Vol. 5) Tissue Engineering and regenerative medicine: Fundamentals. (2nd ed.) (pp. 236-266). Amsterdam, The Netherlands: Elsevier. doi: 10.1016/B978-0-12-803581-8.10221-8

Chapter in Book - Research

Ramaswamy, Y., Lim, K. S., Zreiqat, H., & Lu, Z. (2016). Stem cells for bone regeneration: Role of trophic factors. In A. Zorzi (Ed.), Advanced techniques in bone regeneration. (pp. 357-374). Rijeka, Croatia: Intech. doi: 10.5772/63357

Chapter in Book - Research

Abdelmoneim, D., Porter, G., Duncan, W., Lim, K., Easingwood, R., Woodfield, T., & Coates, D. (2023). Three-dimensional evaluation of the cytotoxicity and antibacterial properties of alpha lipoic acid-capped silver nanoparticle constructs for oral applications. Nanomaterials, 13, 705. doi: 10.3390/nano13040705

Journal - Research Article

Bolam, S. M., Zhu, M. F., Lim, K. S., Konar, S., Oliver, M. H., Buckels, E., … Woodfield, T., … Musson, D. S. (2023). Combined growth factor hydrogel enhances rotator cuff enthesis healing in rat but not sheep model. Tissue Engineering Part A. Advance online publication. doi: 10.1089/ten.TEA.2022.0215

Journal - Research Article

Dai, Y., Qiao, K., Li, D., Isingizwe, P., Liu, H., Liu, Y., Lim, K., Woodfield, T., … Cui, X. (2023). Plant-derived biomaterials and their potential in cardiac tissue repair. Advanced Healthcare Materials. Advance online publication. doi: 10.1002/adhm.202202827

Journal - Research Article

Joukhdar, H., Och, Z., Tran, H., Heu, C., Vasquez, G. M., Sultana, N., … Lim, K. S., … Rnjak-Kovacina, J. (2023). Imparting multi-scalar architectural control into silk materials using a simple multi-functional ice-templating fabrication platform. Advanced Materials Technologies, 2201642. doi: 10.1002/admt.202201642

Journal - Research Article

Longoni, A., Major, G. S., Jiang, S., Farrugia, B. L., Kieser, D. C., Woodfield, T. B. F., … Lim, K. S. (2023). Pristine gelatin incorporation as a strategy to enhance the biofunctionality of poly(vinyl alcohol)-based hydrogels for tissue engineering applications. Biomaterials Science. Advance online publication. doi: 10.1039/d3bm01172k

Journal - Research Article

Major, G., Longoni, A., Simcock, J., Magon, N. J., Harte, J., Bathish, B., Kemp, R., Woodfield, T., & Lim, K. S. (2023). Clinical applicability of visible light-mediated cross-linking for structural soft tissue reconstruction. Advanced Science, 10, 2300538. doi: 10.1002/advs.202300538

Journal - Research Article

Major, G., Simcock, J., Kumar, A., Kleffmann, T., Woodfield, T. B. F., & Lim, K. S. (2023). Comprehensive matrisome profiling of human adipose tissue for soft tissue reconstruction. Advanced Biology. Advance online publication. doi: 10.1002/adbi.202300448

Journal - Research Article

Mekhileri, N. V., Major, G., Lim, K., Mutreja, I., Chitcholtan, K., Phillips, E., Hooper, G., & Woodfield, T. (2023). Biofabrication of modular spheroids as tumour-scale microenvironments for drug screening. Advanced Healthcare Materials, 12, 2201581. doi: 10.1002/adhm.202201581

Journal - Research Article

Soliman, B. G., Longoni, A., Wang, M., Li, W., Bernal, P. N., Cianciosi, A., Lindberg, G. C. J., … Woodfield, T. B. F., … Lim, K. S. (2023). Programming delayed dissolution into sacrificial bioinks for dynamic temporal control of architecture within 3D-bioprinted constructs. Advanced Functional Materials, 2210521. Advance online publication. doi: 10.1002/adfm.202210521

Journal - Research Article

Tran, H. A., Hoang, T. T., Maraldo, A., Do, T. N., Kaplan, D. L., Lim, K. S., & Rnjak-Kovacina, J. (2023). Emerging silk fibroin materials and their applications: New functionality arising from innovations in silk crosslinking. Materials Today. Advance online publication. doi: 10.1016/j.mattod.2023.03.027

Journal - Research Article

Vahala, D., Amos, S. E., Sacchi, M., Soliman, B. G., Hepburn, M. S., Mowla, A., … Lim, K. S., & Choi, Y. S. (2023). 3D volumetric mechanosensation of MCF7 breast cancer spheroids in a linear stiffness gradient GelAGE. Advanced Healthcare Materials, 2301506. Advance online publication. doi: 10.1002/adhm.202301506

Journal - Research Article

Alcala-Orozco, C. R., Mutreja, I., Cui, X., Hooper, G. J., Lim, K. S., & Woodfield, T. B. F. (2022). Hybrid biofabrication of 3D osteoconductive constructs comprising Mg-based nanocomposites and cell-laden bioinks for bone repair. Bone, 154, 116198. doi: 10.1016/j.bone.2021.116198

Journal - Research Article

Cui, X., Alcala-Orozco, C. R., Baer, K., Li, J., Murphy, C. A., Durham, M., Lindberg, G., Hooper, G. J., Lim, K. S., & Woodfield, T. B. F. (2022). 3D bioassembly of cell-instructive chondrogenic and osteogenic hydrogel microspheres containing allogeneic stem cells for hybrid biofabrication of osteochondral constructs. Biofabrication, 14(3), 034101. doi: 10.1088/1758-5090/ac61a3

Journal - Research Article

Kang, B., Park, Y., Hwang, D. G., Kim, D., Yong, U., Lim, K. S., & Jang, J. (2022). Facile bioprinting process for fabricating size-controllable functional microtissues using light-activated decellularized extracellular matrix-based bioinks. Advanced Materials Technologies, 7(1), 2100947. doi: 10.1002/admt.202100947

Journal - Research Article

Karimi, F., Lau, K., Kim, H. N., Och, Z., Lim, K. S., Whitelock, J., … Rnjak-Kovacina, J. (2022). Surface biofunctionalization of silk biomaterials using dityrosine cross-linking. ACS Applied Materials & Interfaces, 14, 31551-31566. doi: 10.1021/acsami.2c03345

Journal - Research Article

Li, J., Cui, X., Lindberg, G. C. J., Alcala-Orozco, C. R., Hooper, G. J., Lim, K. S., & Woodfield, T. B. F. (2022). Hybrid fabrication of photo-clickable vascular hydrogels with additive manufactured titanium implants for enhanced osseointegration and vascularized bone formation. Biofabrication, 14(3), 034103. doi: 10.1088/1758-5090/ac6051

Journal - Research Article

Lu, Y., Cui, X., Zhang, L., Wang, X., Xu, Y., Qin, Z., … Lim, K. S., Charles, C. J., … Tang, J. (2022). The functional role of lipoproteins in atherosclerosis: Novel directions for diagnosis and targeting therapy. Aging & Disease, 13(2), 491-520. doi: 10.14336/AD.2021.0929

Journal - Research Article

Major, G. S., Simcock, J. W., Woodfield, T. B. F., & Lim, K. S. (2022). Overcoming functional challenges in autologous and engineered fat grafting trends. Trends in Biotechnology, 40(1), 77-92. doi: 10.1016/j.tibtech.2021.04.006

Journal - Research Article

Man, K., Alcala, C., Mekhileri, N. V., Lim, K. S., Jiang, L.-H., Woodfield, T. B. F., & Yang, X. B. (2022). GelMA hydrogel reinforced with 3D printed PEGT/PBT scaffolds for supporting epigenetically-activated human bone marrow stromal cells for bone repair. Journal of Functional Biomaterials, 13, 41. doi: 10.3390/jfb13020041

Journal - Research Article

Qiao, K., Xu, L., Tang, J., Wang, Q., Lim, K. S., Hooper, G., Woodfield, T. B. F., … Cui, X. (2022). The advances in nanomedicine for bone and cartilage repair. Journal of Nanobiotechnology, 20, 141. doi: 10.1186/s12951-022-01342-8

Journal - Research Article

Soliman, B. G., Major, G. S., Atienza-Roca, P., Murphy, C. A., Longoni, A., Alcala-Orozco, C. R., … Woodfield, T. B. F., & Lim, K. S. (2022). Development and characterization of gelatin-norbornene bioink to understand the interplay between physical architecture and micro-capillary formation in biofabricated vascularized constructs. Advanced Healthcare Materials, 11(2), 2101873. doi: 10.1002/adhm.202101873

Journal - Research Article

Tang, J., Cui, X., Zhang, Z., Xu, Y., Guo, J., Soliman, B. G., … Lim, K. S., Woodfield, T. B. F., & Zhang, J. (2022). Injection-free delivery of MSC-derived extracellular vesicles for myocardial infarction therapeutics. Advanced Healthcare Materials, 11(5), 2100312. doi: 10.1002/adhm.202100312

Journal - Research Article

Veenendaal, L., Longoni, A., Hooper, G. J., Lim, K. S., Woodfield, T. B. F., & Lindberg, G. C. J. (2022). 3D-bioassembly of VH-spheroids for cartilage regeneration: In vitro evaluation of chondrogenesis, fusion and lateral integration. Advanced Materials Interfaces, 9(31), 2200882. doi: 10.1002/admi.202200882

Journal - Research Article

Zhu, M., Tay, M. L., Lim, K. S., Bolam, S. M., Tuari, D., Callon, K., … Woodfield, T. B. F., … Musson, D. S. (2022). Novel growth factor combination for improving rotator cuff repair: A rat in vivo study. American Journal of Sports Medicine, 50(4), 1044-1053. doi: 10.1177/03635465211072557

Journal - Research Article

Alcala-Orozco, C. R., Cui, X., Hooper, G. J., Lim, K. S., & Woodfield, T. B. F. (2021). Converging functionality: Strategies for 3D hybrid-construct biofabrication and the role of composite biomaterials for skeletal regeneration. Acta Biomaterialia, 132, 188-216. doi: 10.1016/j.actbio.2021.03.008

Journal - Research Article

Aldrich, E. D., Cui, X., Murphy, C. A., Lim, K. S., Hooper, G. J., McIlwraith, C. W., & Woodfield, T. B. F. (2021). Allogeneic mesenchymal stromal cells for cartilage regeneration: A review of in vitro evaluation, clinical experience, and translational opportunities. Stem Cells Translational Medicine, 10(11), 1500-1515. doi: 10.1002/sctm.20-0552

Journal - Research Article

Kim, H., Kang, B., Cui, X., Lee, S.-H., Lee, K., Cho, D.-W., … Woodfield, T. B. F., Lim, K. S., & Jang, J. (2021). Light-activated decellularized extracellular matrix-based bioinks for volumetric tissue analogs at the centimeter scale. Advanced Functional Materials, 31(32), 211252. doi: 10.1002/adfm.202011252

Journal - Research Article

Levato, R., Lim, K. S., Li, W., Usua, A. U., Peña, L. B., Wang, M., … Woodfield, T. B. F., & Malda, J. (2021). High-resolution lithographic biofabrication of hydrogels with complex microchannels from low-temperature-soluble gelatin bioresins. Materials Today Bio, 12, 100162. doi: 10.1016/j.mtbio.2021.100162

Journal - Research Article

Li, W., Wang, M., Mille, L. S., Robledo Lara, J. A., Huerta, V., Uribe Velázquez, T., … Murphy, C. A., … Woodfield, T. B. F., Lim, K. S., & Zhang, Y. S. (2021). A smartphone-enabled portable digital light processing 3D printer. Advanced Materials, 33(35), 2102153. doi: 10.1002/adma.202102153

Journal - Research Article

Lindberg, G. C. J., Cui, X., Durham, M., Veenendaal, L., Schon, B. S., Hooper, G. J., Lim, K. S., & Woodfield, T. B. F. (2021). Probing multicellular tissue fusion of cocultured spheroids: A 3D-bioassembly model. Advanced Science, 8(22), 2103320. doi: 10.1002/advs.202103320

Journal - Research Article

Lindberg, G. C. J., Lim, K. S., Soliman, B. G., Nguyen, A., Hooper, G. J., Narayan, R. J., & Woodfield, T. B. F. (2021). Biological function following radical photo-polymerization of biomedical polymers and surrounding tissues: Design considerations and cellular risk factors. Applied Physics Reviews, 8(1), 011301. doi: 10.1063/5.0015093

Journal - Research Article

Longoni, A., Li, J., Lindberg, G. C. J., Rnjak-Kovacina, J., Wise, L. M., Hooper, G. J., Woodfield, T. B. F., Kieser, D. C., & Lim, K. S. (2021). Strategies for inclusion of growth factors into 3D printed bone grafts. Essays in Biochemistry, 65(3), 569-585. doi: 10.1042/ebc20200130

Journal - Research Article

Man, K., Mekhileri, N., Lim, K. S., Jiang, L.-H., Woodfield, T. B. F., & Yang, X. B. (2021). MI192 induced epigenetic reprogramming enhances the therapeutic efficacy of human bone marrows stromal cells for bone regeneration. Bone, 153, 116138. doi: 10.1016/j.bone.2021.116138

Journal - Research Article

Stamp, L. K., Cameron, V. A., Woodfield, T. B. F., Walker, L., Currie, M., Templeton, E., Pilbrow, A. P., Tabakakis, K., Phillips, E., & Lim, K. S. (2021). Impact of COVID-19 on health research in New Zealand: A case study of a research-intensive campus. Journal of the Royal Society of New Zealand, 51(Suppl. 1), S75-S85. doi: 10.1080/03036758.2020.1867202

Journal - Research Article

Yang, K.-H., Lindberg, G., Soliman, B., Lim, K., Woodfield, T., & Narayan, R. J. (2021). Effect of photoinitiator on precursory stability and curing depth of thiol-ene clickable gelatin. Polymers, 13(11), 1877. doi: 10.3390/polym13111877

Journal - Research Article

Alcala-Orozco, C. R., Mutreja, I., Cui, X., Kumar, D., Hooper, G. J., Lim, K. S., & Woodfield, T. B. F. (2020). Design and characterisation of multi-functional strontium-gelatin nanocomposite bioinks with improved print fidelity and osteogenic capacity. Bioprinting, 18, e00073. doi: 10.1016/j.bprint.2019.e00073

Journal - Research Article

Atienza-Roca, P., Kieser, D., Cui, X., Bathish, B., Ramaswamy, Y., Hooper, G. J., Clarkson, A. N., … Wise, L. M., Woodfield, T. B. F., & Lim, K. S. (2020). Visible light mediated PVA-tyramine hydrogels for covalent incorporation and tailorable release of functional growth factors. Biomaterials Science, 8(18), 5005-5019. doi: 10.1039/D0BM00603C

Journal - Research Article

Baptista, M., Jouhkdar, H., Alcala-Orozco, C. R., Lau, K., Jiang, S., Cui, X., … Woodfield, T. B. F., Lim, K. S., & Rnjak-Kovacina, J. (2020). Silk fibroin photo-lyogels containing microchannels as a biomaterial platform for in situ tissue engineering. Biomaterials Science, 8, 7093-7105. doi: 10.1039/d0bm01010c

Journal - Research Article

Cui, X., Li, J., Hartanto, Y., Durham, M., Tang, J., Zhang, H., Hooper, G., Lim, K., & Woodfield, T. (2020). Advances in extrusion 3D bioprinting: A focus on multicomponent hydrogel-based bioinks. Advanced Healthcare Materials, 9, 1901648. doi: 10.1002/adhm.201901648

Journal - Research Article

Cui, X., Soliman, B. G., Alcala-Orozco, C. R., Li, J., Vis, M. A. M., Santos, M., … Woodfield, T. B. F., … Lim, K. S. (2020). Rapid photocrosslinking of silk hydrogels with high cell density and enhanced shape fidelity. Advanced Healthcare Materials, 9, 1901667. doi: 10.1002/adhm.201901667

Journal - Research Article

Li, J., Cui, X., Hooper, G. J., Lim, K. S., & Woodfield, T. B. F. (2020). Rational design, bio-functionalization and biological performance of hybrid additive manufactured titanium implants for orthopaedic applications: A review. Journal of the Mechanical Behavior of Biomedical Materials, 105, 103671. doi: 10.1016/j.jmbbm.2020.103671

Journal - Research Article

Li, J., Mutreja, I., Hooper, G. J., Clinch, K., Lim, K., Evans, G., & Woodfield, T. B. F. (2020). Combined infection control and enhanced osteogenic differentiation capacity on additive manufactured Ti-6Al-4V are mediated via titania nanotube delivery of novel biofilm inhibitors. Advanced Materials Interfaces, 7, 1901963. doi: 10.1002/admi.201901963

Journal - Research Article

Lim, K. S., Abinzano, F., Nuñez Bernal, P., Albillos Sanchez, A., Atienza-Roca, P., Otto, I. A., … Woodfield, T. B. F., … Levato, R. (2020). One-step photoactivation of a dual-functionalized bioink as cell carrier and cartilage-binding glue for chondral regeneration. Advanced Healthcare Materials, 9, 1901792. doi: 10.1002/adhm.201901792

Journal - Research Article

Lim, K. S., Galarraga, J. H., Cui, X., Lindberg, G. C. J., Burdick, J. A., & Woodfield, T. B. F. (2020). Fundamentals and applications of photo-cross-linking in bioprinting. Chemical Reviews, 120, 10662-10694. doi: 10.1021/acs.chemrev.9b00812

Journal - Research Article

Soliman, B. G., Lindberg, G. C. J., Jungst, T., Hooper, G. J., Groll, J., Woodfield, T. B. F., & Lim, K. S. (2020). Stepwise control of crosslinking in a one-pot system for bioprinting of low-density bioinks. Advanced Healthcare Materials, 9, 1901544. doi: 10.1002/adhm.201901544

Journal - Research Article

Zhang, J., Cui, X., Guo, J., Cao, C., Zhang, Z., Wang, B., … Lim, K., Woodfield, T., … Zhang, J. (2020). Small but significant: Insights and new perspectives of exosomes in cardiovascular disease. Journal of Cellular & Molecular Medicine, 24, 8291-9303. doi: 10.1111/jcmm.15492

Journal - Research Article

Cidonio, G., Alcala-Orozco, C. R., Lim, K. S., Glinka, M., Mutreja, I., Kim, Y.-H., … Woodfield, T. B. F., & Oreffo, R. O. C. (2019). Osteogenic and angiogenic tissue formation in high fidelity nanocomposite Laponite-gelatin bioinks. Biofabrication, 11, 035027. doi: 10.1088/1758-5090/ab19fd

Journal - Research Article

Klotz, B. J., Oosterhoff, L. A., Utomo, L., Lim, K. S., Vallmajo-Martin, Q., Clevers, H., Woodfield, T. B. F., … Gawlitta, D. (2019). A versatile biosynthetic hydrogel platform for engineering of tissue analogues. Advanced Healthcare Materials, 8, 1900979. doi: 10.1002/adhm.201900979

Journal - Research Article

Lim, K. S., Baptista, M., Moon, S., Woodfield, T. B. F., & Rnjak-Kovacina, J. (2019). Microchannels in development, survival, and vascularisation of tissue analogues for regenerative medicine. Trends in Biotechnology, 37(11), 1189-1201. doi: 10.1016/j.tibtech.2019.04.004

Journal - Research Article

Lim, K. S., Klotz, B. J., Lindberg, G. C. J., Melchels, F. P. W., Hooper, G. J., Malda, J., … Woodfield, T. B. F. (2019). Visible light cross-linking of gelatin hydrogels offers an enhanced cell microenvironment with improved light penetration depth. Macromolecular Bioscience, 19(6), 1900098. doi: 10.1002/mabi.201900098

Journal - Research Article

Lindberg, G. C. J., Longoni, A., Lim, K. S., Rosenberg, A. J., Hooper, G. J., Gawlitta, D., & Woodfield, T. B. F. (2019). Intact vitreous humor as a potential extracellular matrix hydrogel for cartilage tissue engineering applications. Acta Biomaterialia, 85, 117-130. doi: 10.1016/j.actbio.2018.12.022

Journal - Research Article

Mutreja, I., Warring, S. L., Lim, K. S., Swadi, T., Clinch, K., Mason, J. M., … Chambers, S. T., … Gerth, M. L., … Woodfield, T. B. F. (2019). Biofilm inhibition via delivery of novel methylthioadenosine nucleosidase inhibitors from PVA-tyramine hydrogels while supporting mesenchymal stromal cell viability. ACS Biomaterials Science & Engineering, 5(2), 748-758. doi: 10.1021/acsbiomaterials.8b01141

Journal - Research Article

Nugent, M., May, J. H., Parker, J. D., Kieser, D. C., Douglas, M., Pereira, R., Lim, K. S., & Hooper, G. J. (2019). Does tranexamic acid reduce knee swelling and improve early function following arthroscopic meniscectomy? A double-blind randomized controlled trial. Orthopaedic Journal of Sports Medicine, 7(8), 2325967119866122. doi: 10.1177/2325967119866122

Journal - Research Article

Parrish, J., Lim, K., Zhang, B., Radisic, M., & Woodfield, T. B. F. (2019). New frontiers for biofabrication and bioreactor design in microphysiological system development. Trends in Biotechnology, 37(12), 1327-1343. doi: 10.1016/j.tibtech.2019.04.009

Journal - Research Article

Soltani, S., Nogaro, M. C., Rougelot, C., Newell, N., Lim, K., & Kieser, D. C. (2019). Spontaneous spinal epidural haematomas in children. European Spine Journal, 28, 2229-2236. doi: 10.1007/s00586-019-05975-6

Journal - Research Article

Vanamala, R., Hammer, N., Soltani, S., Lim, K., Wyatt, M. C., & Kieser, D. C. (2019). Anatomical variations of the saphenous nerve in the adductor canal. Journal of Anesthesiology & Clinical Science, 8, 2. doi: 10.7243/2049-9752-8-2

Journal - Research Article

Klotz, B. J., Lim, K. S., Chang, Y. X., Soliman, B. G., Pennings, I., Melchels, F. P. W., Woodfield, T. B. F., … Gawlitta, D. (2018). Engineering of a complex bone tissue model with endothelialised channels and capillary-like networks. European Cells & Materials, 35, 335-349. doi: 10.22203/eCM.v035a23

Journal - Research Article

Lim, K. S., Levato, R., Costa, P. F., Castilho, M. D., Alcala-Orozco, C. R., van Dorenmalen, K. M. A., … Hooper, G. J., … Woodfield, T. B. F. (2018). Bio-resin for high resolution lithography-based biofabrication of complex cell laden constructs. Biofabrication, 10, 034101. doi: 10.1088/1758-5090/aac00c

Journal - Research Article

Mekhileri, N. V., Lim, K. S., Brown, G. C. J., Mutreja, I., Schon, B. S., Hooper, G. J., & Woodfield, T. B. F. (2018). Automated 3D bioassembly of micro-tissues for biofabrication of hybrid tissue engineered constructs. Biofabrication, 10(2). doi: 10.1088/1758-5090/aa9ef1

Journal - Research Article

Parker, J. D., Lim, K. S., Kieser, D. C., Woodfield, T. B. F., & Hooper, G. J. (2018). Is tranexamic acid toxic to articular cartilage when administered topically? What is the safe dose? Bone & Joint Journal, 100-B(3), 404-412. doi: 10.1302/0301-620X.100B3.BJJ-2017-1135.R1

Journal - Research Article

Parrish, J., Lim, K. S., Baer, K., Hooper, G. J., & Woodfield, T. B. F. (2018). A 96-well microplate bioreactor platform supporting individual dual perfusion and high-throughput assessment of simple or biofabricated 3D tissue models. Lab on a Chip, (18), 2757-2775. doi: 10.1039/c8lc00485d

Journal - Research Article

Bertlein, S., Brown, G., Lim, K. S., Jungst, T., Boeck, T., Blunk, T., … Hooper, G. J., Woodfield, T. B. F., & Groll, J. (2017). Thiol-ene clickable gelatin: A platform bioink for multiple 3D biofabrication technologies. Advanced Materials, 29(44), 1703404. doi: 10.1002/adma.201703404

Journal - Research Article

Brown, G. C. J., Lim, K. S., Farrugia, B. L., Hooper, G. J., & Woodfield, T. B. F. (2017). Covalent incorporation of heparin improves chondrogenesis in photocurable gelatin-methacryloyl hydrogels. Macromolecular Bioscience, 17(12), 1700158. doi: 10.1002/mabi.201700158

Journal - Research Article

Lim, K. S., Schon, B. S., Mekhileri, N. V., Brown, G. C. J., Chia, C. M., Prabakar, S., Hooper, G. J., & Woodfield, T. B. F. (2016). New visible-light photoinitiating system for improved print fidelity in gelatin-based bioinks. ACS Biomaterials Science & Engineering, 2, 1752-1762. doi: 10.1021/acsbiomaterials.6b00149

Journal - Research Article

Roberts, J. J., Naudiyal, P., Lim, K. S., Poole-Warren, L. A., & Martens, P. J. (2016). A comparative study of enzyme initiators for crosslinking phenol-functionalized hydrogels for cell encapsulation. Biomaterials Research, 20, 30. doi: 10.1186/s40824-016-0077-z

Journal - Research Article

Lim, K. S., Ramaswamy, Y., Roberts, J. J., Alves, M.-H., Poole-Warren, L. A., & Martens, P. J. (2015). Promoting cell survival and proliferation in degradable poly(vinyl alcohol)-tyramine hydrogels. Macromolecular Bioscience, 15(10), 1423-1432. doi: 10.1002/mabi.201500121

Journal - Research Article

Lim, K. S., Roberts, J. J., Alves, M.-H., Poole-Warren, L. A., & Martens, P. J. (2015). Understanding and tailoring the degradation of PVA-tyramine hydrogels. Journal of Applied Polymer Science, 132(26), 42142. doi: 10.1002/app.42142

Journal - Research Article

Cheong, G. L. M., Lim, K. S., Jakubowicz, A., Martens, P. J., Poole-Warren, L. A., & Green, R. A. (2014). Conductive hydrogels with tailored bioactivity for implantable electrode coatings. Acta Biomaterialia, 10(3), 1216-1226. doi: 10.1016/j.actbio.2013.12.032

Journal - Research Article

Peterson, M. B., Le-Masurier, S. P., Lim, K., Hook, J. M., Martens, P., & Granville, A. M. (2014). Incorporation of 5-hydroxyindazole into the self-polymerization of dopamine for novel polymer synthesis. Macromolecular Rapid Communications, 35(3), 291-297. doi: 10.1002/marc.201300746

Journal - Research Article

Lim, K. S., Alves, M. H., Poole-Warren, L. A., & Martens, P. J. (2013). Covalent incorporation of non-chemically modified gelatin into degradable PVA-tyramine hydrogels. Biomaterials, 34(29), 7097-7105. doi: 10.1016/j.biomaterials.2013.06.005

Journal - Research Article

Lim, K. S., Kundu, J., Reeves, A., Poole-Warren, L. A., Kundu, S. C., & Martens, P. J. (2012). The influence of silkworm species on cellular interactions with novel PVA/silk sericin hydrogels. Macromolecular Bioscience, 12(3), 322-332. doi: 10.1002/mabi.201100292

Journal - Research Article

Daly, A. C., & Lim, K. S. (2023). High resolution lithography 3D bioprinting. Trends in Biotechnology, 41(3), 262-263. doi: 10.1016/j.tibtech.2022.11.007

Journal - Research Other

Levato, R., & Lim, K. S. (2023). Harnessing light in biofabrication. Biofabrication, 15, 020401. doi: 10.1088/1758-5090/acb50f

Journal - Research Other

Lim, K. S., Zreiqat, H., & Gawlitta, D. (2023). Biofabrication for orthopedic, maxillofacial, and dental applications. Acta Biomaterialia, 156, 1-3. doi: 10.1016/j.actbio.2022.12.064

Journal - Research Other

Zou, Z., Li, H., Yu, K., Ma, K., Wang, Q., Tang, J., … Lim, K., Hooper, G., Woodfield, T., Cui, X., … Tian, K. (2023). The potential role of synovial cells in the progression and treatment of osteoarthritis. Exploration. Advance online publication. doi: 10.1002/EXP.20220132

Journal - Research Other

Murphy, C. A., Lim, K. S., & Woodfield, T. B. F. (2022). Next evolution in organ-scale biofabrication: Bioresin design for rapid high-resolution vat polymerization. Advanced Materials, 34, 2107759. doi: 10.1002/adma.202107759

Journal - Research Other

Rnjak-Kovacina, J., Choi, Y. S., & Lim, K. S. (2022). Biofabrication Applications. Advanced Healthcare Materials, 11(24), 2202934. doi: 10.1002/adhm.202202934

Journal - Research Other

Gentile, C., Lim, K. S., & Vozzi, G. (2021). Editorial: 3D bioprinting of vascularized tissues for in vitro and in vivo applications. Frontiers in Bioengineering & Biotechnology, 9, 754124. doi: 10.3389/fbioe.2021.754124

Journal - Research Other

Lim, K. S., & Woodfield, T. B. F. (2015). Silk hydrogels for tissue engineering. Scripta-Ingenia, December(5), 3-7.

Journal - Research Other

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