Vasantharajan, S. S., Barnett, E., Gray, E. S., Rodger, E. J., Eccles, M. R., Pattison, S., Munro, F., & Chatterjee, A. (2023). Size-based method for enrichment of circulating tumor cells from blood of colorectal cancer patients. In G. J. Seymour, M. P. Cullinan, N. C. K. Heng & P. R. Cooper (Eds.), Oral biology: Molecular techniques and applications: Methods in molecular biology (Vol. 2588). (3rd ed.) (pp. 231-248). New York, NY: Springer. doi: 10.1007/978-1-0716-2780-8_15

Chapter in Book - Research

Al Momani, S., Rodger, E. J., Stockwell, P. A., Eccles, M. R., & Chatterjee, A. (2022). Generating sequencing-based DNA methylation maps from low DNA input samples. In J. Horsfield & J. Marsman (Eds.), Chromatin: Methods and protocols: Methods in molecular biology (Vol. 2458). (pp. 3-21). New York, NY: Springer. doi: 10.1007/978-1-0716-2140-0_1

Chapter in Book - Research

Chatterjee, A., Ahn, A., Rodger, E. J., Stockwell, P. A., & Eccles, M. R. (2018). A guide for designing and analyzing RNA-Seq data. In N. Raghavachari & N. Garcia-Reyero (Eds.), Gene expression analysis: Methods in molecular biology (Vol. 1783). (pp. 35-80). New York, NY: Humana Press. doi: 10.1007/978-1-4939-7834-2_3

Chapter in Book - Research

Chatterjee, A., Rodger, E. J., Morison, I. M., Eccles, M. R., & Stockwell, P. A. (2017). Tools and strategies for analysis of genome-wide and gene-specific DNA methylation patterns. In G. J. Seymour, M. P. Cullinan & N. C. K. Heng (Eds.), Oral biology: Molecular techniques and applications: Methods in molecular biology (Vol. 1537). (2nd ed.) (pp. 249-277). New York, NY: Springer. doi: 10.1007/978-1-4939-6685-1_15

Chapter in Book - Research

Yoon, H.-S., & Eccles, M. R. (2011). Mild forms of Alport syndrome: Hereditary nephropathy in the absence of extra-renal features. In S. S. Prabhakar (Ed.), An update of glomerulopathies: Clinical and treatment aspects. (pp. 417-436). Rijeka, Croatia: InTech. Retrieved from http://www.intechopen.com

Chapter in Book - Research

Eccles, M. R. (2008). PAX2 and the Renal-Coloboma Syndrome. In C. J. Epstein, R. P. Erickson & A. Wynshaw-Boris (Eds.), Inborn errors of development: The molecular basis of clinical disorders of morphogenesis. (2nd ed.) (pp. 796-802). Oxford University Press.

Chapter in Book - Research

Eccles, M. R. (2004). PAX2 and the renal-coloboma syndrome. In C. J. Epstein, R. P. Erickson & A. Wynshaw-Boris (Eds.), Inborn errors of development: The molecular basis of clinical disorders of morphogenesis. (pp. 633-642). Oxford University Press.

Chapter in Book - Research

Eccles, M. R., Bockett, N., & Stayner, C.-A. K. (2003). PAX2 and Renal-Coloboma Syndrome. In P. D. Vize, A. S. Woolf & J. B. L. Bard (Eds.), The kidney. (pp. 411-432). San Diego, USA: Elsevier Science.

Chapter in Book - Research

Fitzgerald, S., Blenkiron, C., Stephens, R., Mathy, J. A., Somers-Edgar, T., Rolfe, G., … Jackson, C., Eccles, M., … Rodger, E., … Guilford, P., … Print, C. G. (2023). Dynamic ctDNA mutational complexity in patients with melanoma receiving immunotherapy. Molecular Diagnosis & Therapy. Advance online publication. doi: 10.1007/s40291-023-00651-4

Journal - Research Article

Jasiak, A., Koczkowska, M., Stukan, M., Wydra, D., Biernat, W., Izycka-Swieszewska, E., … Eccles, M. R., Walker, L., … Ratajska, M. (2023). Analysis of BRCA1 and BRCA2 alternative splicing in predisposition to ovarian cancer. Experimental & Molecular Pathology. Advance online publication. doi: 10.1016/j.yexmp.2023.104856

Journal - Research Article

Keighley, L. M., Lynch-Sutherland, C. F., Almomani, S. N., Eccles, M. R., & Macaulay, E. C. (2023). Unveiling the hidden players: The crucial role of transposable elements in the placenta and their potential contribution to pre-eclampsia. Placenta. Advance online publication. doi: 10.1016/j.placenta.2023.05.017

Journal - Research Article

Li, L., Li, C. G., Almomani, S. N., Hossain, S. M., & Eccles, M. R. (2023). Co-expression of multiple PAX genes in renal cell carcinoma (RCC) and correlation of high PAX expression with favorable clinical outcome in RCC patients. International Journal of Molecular Sciences, 24, 11432. doi: 10.3390/ijms241411432

Journal - Research Article

Lynch-Sutherland, C. F., McDougall, L. I., Stockwell, P. A., Almomani, S. N., Weeks, R. J., Ludgate, J. L., … Chatterjee, A., … Eccles, M. R., & Macaulay, E. C. (2023). The transposable element-derived transcript of LIN28B has a placental origin and is not specific to tumours. Molecular Genetics & Genomics. Advance online publication. doi: 10.1007/s00438-023-02033-1

Journal - Research Article

Ravindran Menon, D., Hammerlindl, H., Gimenez, G., Hammerlindl, S., Zuegner, E., Torrano, J., … Eccles, M. R., … Schaider, H. (2023). H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase. Drug Resistance Updates, 71, 100993. doi: 10.1016/j.drup.2023.100993

Journal - Research Article

Rodger, E. J., Gimenez, G., Ajithkumar, P., Stockwell, P. A., Almomani, S., Bowden, S. A., Leichter, A. L., Ahn, A., Pattison, S., McCall, J. L., … Frizelle, F. A., Eccles, M. R., Purcell, R. V., & Chatterjee, A. (2023). An epigenetic signature of advanced colorectal cancer metastasis. iScience, 26(6), 106986. doi: 10.1016/j.isci.2023.106986

Journal - Research Article

Ahmed, F., Tseng, H.-Y., Ahn, A., Gunatilake, D., Alavi, S., Eccles, M., … Al Emran, A. (2022). Repurposing melanoma chemotherapy to activate inflammasomes in treatment of BRAF/MAPK inhibitor resistant melanoma. Journal of Investigative Dermatology, 142, 1444-1455. doi: 10.1016/j.jid.2021.09.030

Journal - Research Article

Hossain, S. M., Gimenez, G., Stockwell, P. A., Tsai, P., Print, C. G., Rys, J., … Jackson, C., Chatterjee, A., & Eccles, M. R. (2022). Innate immune checkpoint inhibitor resistance is associated with melanoma sub-types exhibiting invasive and de-differentiated gene expression signatures. Frontiers in Immunology, 13, 955063. doi: 10.3389/fimmu.2022.955063

Journal - Research Article

Powell, R. M., Pattison, S., Moravec, J. C., Bhat, B., Guirguis, N., Markie, D., Jones, G. T., … Print, C. G., Morison, I. M., Gavryushkin, A., … Eccles, M. R., & Macaulay, E. C. (2022). Tuberous sclerosis complex: A complex case. Molecular Case Studies, 8, a006182. doi: 10.1101/mcs.a006182

Journal - Research Article

Vasantharajan, S. S., Barnett, E., Gray, E. S., McCall, J. L., Rodger, E. J., Eccles, M. R., Munro, F., Pattison, S., & Chatterjee, A. (2022). Assessment of a size-based method for enriching circulating tumour cells in colorectal cancer. Cancers, 14, 3446. doi: 10.3390/cancers14143446

Journal - Research Article

Ahn, A., Rodger, E. J., Motwani, J., Gimenez, G., Stockwell, P. A., Parry, M., … Chatterjee, A., & Eccles, M. R. (2021). Transcriptional reprogramming and constitutive PD-L1 expression in melanoma are associated with dedifferentiation and activation of interferon and tumour necrosis factor signalling pathways. Cancers, 13, 4250. doi: 10.3390/cancers13174250

Journal - Research Article

McDougall, L. I., Powell, R. M., Ratajska, M., Lynch-Sutherland, C. F., Hossain, S. M., Wiggins, G. A. R., … Motwani, J., Macaulay, E. C., Reid, G., Walker, L. C., … Eccles, M. R. (2021). Differential expression of BARD1 isoforms in melanoma. Genes, 12(2), 320. doi: 10.3390/genes12020320

Journal - Research Article

McDougall, L., Kueh, J. T. B., Ward, J., Tyndall, J. D. A., Woolley, A. G., Mehta, S., Stayner, C., Larsen, D. S., & Eccles, M. R. (2021). Chemical synthesis of the PAX protein inhibitor EG1 and its ability to slow the growth of human colorectal carcinoma cells. Frontiers in Oncology, 11, 709540. doi: 10.3389/fonc.2021.709540

Journal - Research Article

Motwani, J., Rodger, E. J., Stockwell, P. A., Baguley, B. C., Macaulay, E. C., & Eccles, M. R. (2021). Genome-wide DNA methylation and RNA expression differences correlate with invasiveness in melanoma cell lines. Epigenomics, 13(8), 577-598. doi: 10.2217/epi-2020-0440

Journal - Research Article

Paumann-Page, M., Kienzl, N. F., Motwani, J., Bathish, B., Paton, L. N., Magon, N. J., … Eccles, M. R., & Winterbourn, C. C. (2021). Peroxidasin protein expression and enzymatic activity in metastatic melanoma cell lines are associated with invasive potential. Redox Biology, 46, 102090. doi: 10.1016/j.redox.2021.102090

Journal - Research Article

Shyam, S., Eccles, M. R., Rodger, E. J., Pattison, S., McCall, J. L., Gray, E. S., … Chatterjee, A. (2021). The epigenetic landscape of circulating tumour cells. Biochimica et Biophysica Acta: Reviews on Cancer, 1875(188514). doi: 10.1016/j.bbcan.2021.188514

Journal - Research Article

Smith, J., Banerjee, R., Waly, R., Urbano, A., Gimenez, G., Day, R., Eccles, M. R., Weeks, R. J., & Chatterjee, A. (2021). Locus-specific DNA methylation editing in melanoma cell lines using a CRISPR-based system. Cancers, 13, 5433. doi: 10.3390/cancers13215433

Journal - Research Article

Stockwell, P. A., Lynch-Sutherland, C. F., Chatterjee, A., Macaulay, E. C., & Eccles, M. R. (2021). RepExpress: A novel pipeline for the quantification and characterization of transposable element expression from RNA-seq data. Current Protocols, 1(8), e206. doi: 10.1002/cpz1.206

Journal - Research Article

Tran, K. B., Gimenez, G., Tsai, P., Kolekar, S., Rodger, E., Chatterjee, A., … Eccles, M. R., … Shepherd, P. R. (2021). Genomic and signalling pathway characterisation of the NZM panel of melanoma cell lines: A valuable model for studying the impact of genetic diversity in melanoma. Pigment Cell & Melanoma Research, 34(1), 136-143. doi: 10.1111/pcmr.12908

Journal - Research Article

Bowden, S. A., Stockwell, P. A., Rodger, E. J., Parry, M. F., Eccles, M. R., Stayner, C., & Chatterjee, A. (2020). Extensive inter-cyst DNA methylation variation in autosomal dominant polycystic kidney disease revealed by genome scale sequencing. Frontiers in Genetics, 11, 348. doi: 10.3389/fgene.2020.00348

Journal - Research Article

Honda, S., Chatterjee, A., Leichter, A. L., Miyagi, H., Minato, M., Fujiyoshi, S., … Eccles, M. R. (2020). A microRNA cluster in the DLK1-DIO3 imprinted region on chromosome 14q32.2 is dysregulated in metastatic hepatoblastomas. Frontiers in Oncology, 10, 513601. doi: 10.3389/fonc.2020.513601

Journal - Research Article

Lynch-Sutherland, C. F., Chatterjee, A., Stockwell, P. A., Eccles, M. R., & Macaulay, E. C. (2020). Reawakening the developmental origins of cancer through transposable elements. Frontiers in Oncology, 10, 468. doi: 10.3389/fonc.2020.00468

Journal - Research Article

Tiffen, J., Gallagher, S., Filipp, F., Gunatilake, D., Al Emran, A., Cullinane, C., … Chatterjee, A., Rodger, E. J., Eccles, M. R., & Hersey, P. (2020). EZH2 cooperates with DNA methylation to downregulate key tumour suppressors and IFN signatures in melanoma. Journal of Investigative Dermatology, 140, 2442-2454.e5. doi: 10.1016/j.jid.2020.02.042

Journal - Research Article

Macdonald, C. M., Kunnen, B., Stayner, C., & Eccles, M. R. (2019). Designing phantoms to accurately replicate circular depolarization in biological scattering media. Applied Optics, 58(35), 9577-9584. doi: 10.1364/AO.58.009577

Journal - Research Article

Rodger, E. J., Chatterjee, A., Stockwell, P. A., & Eccles, M. R. (2019). Characterisation of DNA methylation changes in EBF3 and TBC1D16 associated with tumour progression and metastasis in multiple cancer types. Clinical Epigenetics, 11, 114. doi: 10.1186/s13148-019-0710-5

Journal - Research Article

Roy, R., Chatterjee, A., Das, D., Ray, A., Singh, R., Chattopadhyay, E., … Eccles, M., … Roy, B. (2019). Genome-wide miRNA methylome analysis in oral cancer: Possible biomarkers associated with patient survival. Epigenomics, 11(5), 473-487. doi: 10.2217/epi-2018-0078

Journal - Research Article

Stayner, C., Brooke, D. G., Bates, M., & Eccles, M. R. (2019). Targeted therapies for autosomal dominant polycystic kidney disease. Current Medicinal Chemistry, 26(17), 3081-3102. doi: 10.2174/0929867325666180508095654

Journal - Research Article

Bowden, S. A., Rodger, E. J., Bates, M., Chatterjee, A., Eccles, M. R., & Stayner, C. (2018). Genome-scale single nucleotide resolution analysis of DNA methylation in human autosomal dominant polycystic kidney disease. American Journal of Nephrology, 48(6), 415-424. doi: 10.1159/000494739

Journal - Research Article

Chatterjee, A., Rodger, E. J., & Eccles, M. R. (2018). Epigenetic drivers of tumourigenesis and cancer metastasis. Seminars in Cancer Biology, 51, 149-159. doi: 10.1016/j.semcancer.2017.08.004

Journal - Research Article

Chatterjee, A., Rodger, E. J., Ahn, A., Stockwell, P. A., Parry, M., Motwani, J., … Eccles, M. R., & Hersey, P. (2018). Marked global DNA hypomethylation is associated with constitutive PD-L1 expression in melanoma. iScience, 4, 312-325. doi: 10.1016/j.isci.2018.05.021

Journal - Research Article

Kaur, G., Li, C. G., Chantry, A., Stayner, C., Horsfield, J., & Eccles, M. R. (2018). SMAD proteins directly suppress PAX2 transcription downstream of transforming growth factor-beta 1 (TGF-β1) signalling in renal cell carcinoma. Oncotarget, 9(42), 26852-26867. doi: 10.18632/oncotarget.25516

Journal - Research Article

Chatterjee, A., Macaulay, E. C., Ahn, A., Ludgate, J. L., Stockwell, P. A., Weeks, R. J., Parry, M. F., Foster, T. J., … Eccles, M. R., & Morison, I. M. (2017). Comparative assessment of DNA methylation patterns between reduced representation bisulfite sequencing and Sequenom EpiTyper methylation analysis. Epigenomics, 9(6), 823-832. doi: 10.2217/epi-2016-0176

Journal - Research Article

Chatterjee, A., Stockwell, P. A., Ahn, A., Rodger, E. J., Leichter, A. L., & Eccles, M. R. (2017). Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis. Oncotarget, 8(4), 6085-6101. doi: 10.18632/oncotarget.14042

Journal - Research Article

Leichter, A. L., Sullivan, M. J., Eccles, M. R., & Chatterjee, A. (2017). MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours. Molecular Cancer, 16(1), 15. doi: 10.1186/s12943-017-0584-0

Journal - Research Article

Ludgate, J. L., Wright, J., Stockwell, P. A., Morison, I. M., Eccles, M. R., & Chatterjee, A. (2017). A streamlined method for analysing genome-wide DNA methylation patterns from low amounts of FFPE DNA. BMC Medical Genomics, 10, 54. doi: 10.1186/s12920-017-0290-1

Journal - Research Article

Macaulay, E. C., Chatterjee, A., Cheng, X., Baguley, B. C., Eccles, M. R., & Morison, I. M. (2017). The genes of life and death: A potential role for placental-specific genes in cancer: Active retrotransposons in the placenta encode unique functional genes that may also be used by cancer cells to promote malignancy. BioEssays, 39(11), 1700091. doi: 10.1002/bies.201700091

Journal - Research Article

Stayner, C., Poole, C. A., McGlashan, S. R., Pilanthananond, M., Brauning, R., Markie, D., … Slobbe, L., … Parker, K., Wiles, A., … Leichter, A., Leask, M., … Jennings, M., Horsfield, J. A., Walker, R. J., & Eccles, M. R. (2017). An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations. Scientific Reports, 7, 1601. doi: 10.1038/s41598-017-01519-4

Journal - Research Article

Chatterjee, A., Stockwell, P. A., Rodger, E. J., Parry, M. F., & Eccles, M. R. (2016). scan_tcga tools for integrated epigenomic and transcriptomic analysis of tumor subgroups. Epigenomics, 8(10), 1315-1330. doi: 10.2217/epi-2016-0063

Journal - Research Article

Jones, A. M., Ferguson, P., Gardner, J., Rooker, S., Sutton, T., Ahn, A., Chatterjee, A., … Sarwar, M., Emanuel, P., Kenwright, D., … Eccles, M. R. (2016). NRAS and EPHB6 mutation rates differ in metastatic melanomas of patients in the North Island versus South Island of New Zealand. Oncotarget, 7(27), 41017-41030. doi: 10.18632/oncotarget.9351

Journal - Research Article

Moktefi, A., Zhang, S.-Y., Vachin, P., Ory, V., Henique, C., Audard, V., … Eccles, M., … Pawlak, A. (2016). Repression of CMIP transcription by WT1 is relevant to podocyte health. Kidney International, 90(6), 1298-1311. doi: 10.1016/j.kint.2016.07.016

Journal - Research Article

Chatterjee, A., Leichter, A. L., Fan, V., Tsai, P., Purcell, R. V., Sullivan, M. J., & Eccles, M. R. (2015). A cross comparison of technologies for the detection of microRNAs in clinical FFPE samples of hepatoblastoma patients. Scientific Reports, 5, 10438. doi: 10.1038/srep10438

Journal - Research Article

Kunnen, B., Macdonald, C., Doronin, A., Jacques, S., Eccles, M., & Meglinski, I. (2015). Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media. Journal of Biophotonics, 8(4), 317-323. doi: 10.1002/jbio.201400104

Journal - Research Article

Leichter, A. L., Purcell, R. V., Sullivan, M. J., Eccles, M. R., & Chatterjee, A. (2015). Multi-platform microRNA profiling of hepatoblastoma patients using formalin fixed paraffin embedded archival samples. GigaScience, 4, 54. doi: 10.1186/s13742-015-0099-9

Journal - Research Article

Mainini, F., Larsen, D. S., Webster, G. A., Young, S. L., & Eccles, M. R. (2015). Bridging small molecules to modified bacterial microparticles using a disulphide linkage: MIS416 as a cargo delivery system. PLoS ONE, 10(12), e0145403. doi: 10.1371/journal.pone.0145403

Journal - Research Article

Pinnapureddy, A. R., Stayner, C., McEwan, J., Baddeley, O., Forman, J., & Eccles, M. R. (2015). Large animal models of rare genetic disorders: Sheep as phenotypically relevant models of human genetic disease. Orphanet Journal of Rare Diseases, 10, 107. doi: 10.1186/s13023-015-0327-5

Journal - Research Article

Eccles, M. R., & Stayner, C. A. (2014). Polycystic kidney disease: Where gene dosage counts. F1000 Prime Reports, 6, 24. doi: 10.12703/p6-24

Journal - Research Article

Hung, N., Chen, Y.-J., Taha, A., Olivecrona, M., Boet, R., Wiles, A., … Shaw, A., Eiholzer, R., Baguley, B. C., Eccles, M. R., Braithwaite, A. W., MacFarlane, M., Royds, J. A., & Slatter, T. (2014). Increased paired box transcription factor 8 has a survival function in Glioma. BMC Cancer, 14, 159. doi: 10.1186/1471-2407-14-159

Journal - Research Article

Stevens, A. J., Stuffrein-Roberts, S., Cree, S. L., Gibb, A., Miller, A. L., Doudney, K., Aitchison, A., Eccles, M. R., Joyce, P. R., … Kennedy, M. A. (2014). G-quadruplex structures and CpG methylation cause drop-out of the maternal allele in polymerase chain reaction amplification of the imprinted MEST gene promoter. PLoS ONE, 9(12), e113955. doi: 10.1371/journal.pone.0113955

Journal - Research Article

Eccles, M. R., He, S., Ahn, A., Slobbe, L. J., Jeffs, A. R., Yoon, H.-S., & Baguley, B. C. (2013). MITF and PAX3 play distinct roles in melanoma cell migration: Outline of a “genetic switch” theory involving MITF and PAX3 in proliferative and invasive phenotypes of melanoma. Frontiers in Oncology, 3, 229. doi: 10.3389/fonc.2013.00229

Journal - Research Article

Wu, M. K., Sabbaghian, N., Xu, B., Addidou-Kalucki, S., Bernard, C., Zou, D., Reeve, A. E., Eccles, M. R., … Foulkes, W. D. (2013). Biallelic DICER1 mutations occur in Wilms tumours. Journal of Pathology, 230(2), 154-164. doi: 10.1002/path.4196

Journal - Research Article

Bower, M., Salomon, R., Allanson, J., Antignac, C., Benedicenti, F., Benetti, E., … Dixon, J., … Eccles, M., … Heidet, L. (2012). Update of PAX2 mutations in renal coloboma syndrome and establishment of locus-specific database. Human Mutation, 33(3), 457-466. doi: 10.1002/humu.22020

Journal - Research Article

Burger, M. C., Brucker, D. P., Baumgarten, P., Ronellenfitsch, M. W., Wanka, C., Hasselblatt, M., Eccles, M. R., … Steinbach, J. P. (2012). PAX2 is an antiapoptotic molecule with deregulated expression in medulloblastoma. International Journal of Oncology, 41(1), 235-241. doi: 10.3892/ijo.2012.1446

Journal - Research Article

Ineson, J., Stayner, C., Hazlett, J., Slobbe, L., Robson, E., Legge, M., & Eccles, M. R. (2012). Somatic reactivation of expression of the silent maternal Mest allele and acquisition of normal reproductive behaviour in a colony of Peg1/Mest mutant mice. Journal of Reproduction & Development, 58(4), 490-500.

Journal - Research Article

Li, C. G., & Eccles, M. R. (2012). PAX genes in cancer: Friends or foes? Frontiers in Genetics, 3, 6. doi: 10.3389/fgene.2012.00006

Journal - Research Article

McEwan, M. V., Eccles, M. R., & Horsfield, J. A. (2012). Cohesin is required for activation of MYC by estradiol. PLoS ONE, 7(11), e49160. doi: 10.1371/journal.pone.0049160

Journal - Research Article

Stayner, C., Shields, J., Slobbe, L., Shillingford, J. M., Weimbs, T., & Eccles, M. R. (2012). Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1^-/- mutant mouse embryos: An investigation of the feasibility of renal cyst prevention in the foetus. Nephrology, 17(8), 739-747. doi: 10.1111/j.1440-1797.2012.01639.x

Journal - Research Article

He, S., Li, C. G., Slobbe, L., Glover, A., Marshall, E., Baguley, B. C., & Eccles, M. R. (2011). PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression. Melanoma Research, 21(1), 24-34. doi: 10.1097/CMR.0b013e328341c7e0

Journal - Research Article

Li, C. G., Nyman, J. E., Braithwaite, A. W., & Eccles, M. R. (2011). PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein. Oncogene, 30, 4824-4834. doi: 10.1038/onc.2011.190

Journal - Research Article

Otto, E. A., Ramaswami, G., Janssen, S., Chaki, M., Allen, S. J., Zhou, W., … and the GPN Study Group, including Eccles, M. (2011). Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy. Journal of Medical Genetics, 48, 105-116. doi: 10.1136/jmg.2010.082552

Journal - Research Article

He, S., Yoon, H.-S., Suh, B.-J., & Eccles, M. R. (2010). PAX3 is extensively expressed in benign and malignant tissues of the melanocytic lineage in humans [Letter]. Journal of Investigative Dermatology, 130, 1465-1468. doi: 10.1038/jid.2009.434

Journal - Research Article

Hueber, P.-A., Fukuzawa, R., Elkares, R., Chu, L., Blumentkrantz, M., He, S.-J., Anaka, M. R., Reeve, A. E., Eccles, M. R., … Goodyer, P. R. (2009). PAX3 is expressed in the stromal compartment of the developing kidney and in Wilms tumors with myogenic phenotype. Pediatric & Developmental Pathology, 12(5), 347-354. doi: 10.2350/08-05-0466.1

Journal - Research Article

Jeffs, A. R., Glover, A. C., Slobbe, L. J., Wang, L., He, S., Hazlett, J. A., Awasthi, A., Woolley, A. G., … Print, C. G., … Eccles, M. R. (2009). A gene expression signature of invasive potential in metastatic melanoma cells. PLoS ONE, 4(12), e8461. doi: 10.1371/journal.pone.0008461

Journal - Research Article

Mönnich, M., Banks, S., Eccles, M., Dickinson, E., & Horsfield, J. (2009). Expression of cohesin and condensin genes during zebrafish development supports a non-proliferative role for cohesin. Gene Expression Patterns, 9(8), 586-594. doi: 10.1016/j.gep.2009.08.004

Journal - Research Article

Chen, Y.-J., Campbell, H. G., Wiles, A. K., Eccles, M. R., Reddel, R. R., Braithwaite, A. W., & Royds, J. A. (2008). PAX8 regulates telomerase reverse transcriptase and telomerase RNA component in glioma. Cancer Research, 68(14), 5724-5732. doi: 10.1158/0008-5472.CAN-08-0058

Journal - Research Article

Frost, V., Grocott, T., Eccles, M. R., & Chantry, A. (2008). Self-regulated Pax gene expression and modulation by the TGFβ superfamily. Critical Reviews in Biochemistry & Molecular Biology, 43(6), 371-391. doi: 10.1080/10409230802486208

Journal - Research Article

Hueber, P.-A., Iglesias, D., Chu, L. L., Eccles, M., & Goodyer, P. (2008). In vivo validation of PAX2 as a target for renal cancer therapy. Cancer Letters, 265, 148-155. doi: 10.1016/j.canlet.2008.02.016

Journal - Research Article

Lu, W., van Eerde, A. M., Fan, X., Quintero-Rivera, F., Kulkarni, S., Ferguson, H., … Eccles, M. R., … Maas, R. L. (2007). Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux. American Journal of Human Genetics, 80(4), 616-632. doi: 10.1086/512735

Journal - Research Article

Wilson, J. C., Yoon, H.-S., Walker, R. J., & Eccles, M. R. (2007). A novel Cys1638Tyr NC1 domain substitution in α5(IV) collagen causes Alport syndrome with late onset renal failure without hearing loss or eye abnormalities. Nephrology Dialysis Transplantation, 22(5), 1338-1346. doi: 10.1093/ndt/gfl793

Journal - Research Article

Dziarmaga, A., Eccles, M., & Goodyer, P. (2006). Suppression of ureteric bud apoptosis rescues nephron endowment and adult renal function in Pax2 mutant mice. Journal of the American Society of Nephrology, 17, 1568-1575.

Journal - Research Article

Dziarmaga, A., Hueber, P.-A., Iglesias, D., Hache, N., Jeffs, A., Gendron, N., … Eccles, M., & Goodyer, P. (2006). Neuronal apoptosis inhibitory protein is expressed in developing kidney and is regulated by PAX2. American Journal of Physiology: Renal Physiology, 291, F913-F920. doi: 10.1152/ajprenal.00004.2006

Journal - Research Article

Hueber, P.-A., Waters, P., Clarke, P., Eccles, M., & Goodyer, P. (2006). PAX2 inactivation enhances cisplatin-induced apoptosis in renal carcinoma cells. Kidney International, 69, 1139-1145.

Journal - Research Article

Robson, E. J. D., He, S.-J., & Eccles, M. R. (2006). A PANorama of PAX genes in cancer and development. Nature Reviews Cancer, 6, 52-62.

Journal - Research Article

Stayner, C., Iglesias, D. M., Goodyer, P. R., Ellis, L., Germino, G., Zhou, J., & Eccles, M. R. (2006). Pax2 gene dosage influences cystogenesis in autosomal dominant polycystic kidney disease. Human Molecular Genetics, 15(24), 3520-3528.

Journal - Research Article

Torban, E., Dziarmaga, A., Iglesias, D., Chu, L. L., Vassilieva, T., Little, M., Eccles, M., … Goodyer, P. (2006). PAX2 activates WNT4 expression during mammalian kidney development. Journal of Biological Chemistry, 281(18), 12705-12712.

Journal - Research Article

Utsch, B., Sayer, J. A., Attanasio, M., Pereira, R. R., Eccles, M., Hennies, H.-C., … Hildebrandt, F. (2006). Identification of the first AHI1 gene mutations in nephronophthisis-associated Joubert syndrome. Pediatric Nephrology, 21, 32-35.

Journal - Research Article

He, S.-J., Stevens, G., Braithwaite, A. W., & Eccles, M. R. (2005). Transfection of melanoma cells with antisense PAX3 oligonucleotides additively complements cisplatin-induced cytotoxicity. Molecular Cancer Therapeutics, 4(6), 996-1003.

Journal - Research Article

Johnstone, A. C., Davidson, B. I., Roe, A. R., Eccles, M. R., & Jolly, R. D. (2005). Congenital polycystic kidney disease in lambs. New Zealand Veterinary Journal, 53(5), 307-314.

Journal - Research Article

Clark, P., Dziarmaga, A., Eccles, M., & Goodyer, P. (2004). Rescue of defective branching nephrogenesis in renal-coloboma syndrome by the caspase inhibitor, Z-VAD-fmk. Journal of the American Society of Nephrology, 15, 299-305.

Journal - Research Article

Filipovska, A., Eccles, M. R., Smith, R. A. J., & Murphy, M. P. (2004). Delivery of antisense peptide nucleic acids (PNAs) to the cytosol by disulphide conjugation to a lipophilic cation. FEBS Letters, 556, 180-186.

Journal - Research Article

Muratovska, A., & Eccles, M. R. (2004). Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells. FEBS Letters, 558, 63-68.

Journal - Research Article

Discenza, M. T., He, S., Lee, T. H., Chu, L. L., Bolon, B., Goodyer, P., Eccles, M., & Pelletier, J. (2003). WT1 is a modifier of the Pax2 mutant phenotype: Cooperation and interaction between WT1 and Pax2. Oncogene, 22(50), 8145-8155. doi: 10.1038/sj.onc.1206997

Journal - Research Article

Dziarmaga, A., Clark, P., Stayner, C.-A. K., Julien, J. P., Torban, E., Goodyer, P., & Eccles, M. R. (2003). Ureteric bud apoptosis and renal hypoplasia in transgenic PAX2-Bax fetal mice mimics the renal-coloboma syndrome. Journal of the American Society of Nephrology, 14(11), 2767-2774.

Journal - Research Article

Edwards, S. J., Hananeia, L., Eccles, M. R., Zhang, Y.-F., & Braithwaite, A. (2003). The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions. Oncogene, 22(29), 4517-4523.

Journal - Research Article

Fukuzawa, R., Eccles, M. R., Ikeda, M., & Hata, J.-I. (2003). Embryonal hyperplasia of Bowman's capsular epithelium in patients with WT1 mutations. Pediatric Nephrology, 18(1), 9-13.

Journal - Research Article

Gough, S. M., McDonald, M., Chen, X.-N., Korenberg, J. R., Neri, A., Kahn, T., Eccles, M. R., & Morris, C. M. (2003). Refined physical map of the human PAX2/HOX11/NFKB2 cancer gene region at 10q24 and relocalization of the HPV6AI1 viral integration site to 14q13.3-q21.1. BMC Genomics, 4(1), 9.

Journal - Research Article

Muratovska, A., Zhou, C., He, S., Goodyer, P., & Eccles, M. R. (2003). Paired-box genes are frequently expressed in cancer and often required for cancer cell survival. Oncogene, 22(39), 7989-7997.

Journal - Research Article

Eccles, M. R., He, S., Legge, M., Kumar, R., Fox, J., Zhou, C., French, M., & Tsai, R. (2002). PAX genes in development and disease: The role of PAX2 in urogenital tract development. International Journal of Developmental Biology, 46, 535-544.

Journal - Research Article

Chen, F., Colin, G. B., Liu, K. C., Beier, D. R., Eccles, M. R., Nishina, P. M., … Epstein, J. A. (2001). Characterization of the Murine Lbx2 promoter, identification of the human homologue, and evaluation as a candidate for Alstrom syndrome. Genomics, 74(2), 219-227.

Journal - Research Article

Gus, P. I., de Souza, C. F. M., Porteous, S. H., & Eccles, M. R. (2001). Renal-coloboma syndrome in a Brazilian family. Archives of Ophthalmology, 119(2), 1563-1565.

Journal - Research Article

Walker, R. J., Dixon, S., Ruger, B. M., Davis, P. F., Hildebrant, F., Kremer, M., Eccles, M. R., McNoe, L. A., … Reid, J. J. (2001). Familial fibronectin glomerulopathy: Analysis of chromosome 1q32 and uteroglobulin gene loci in a large New Zealand family. Nephrology, 6, 191-197.

Journal - Research Article

Ades, L., Davies, R., Haan, E. A., Holman, K. J., Watson, K. C., Sreetharan, D., … Eccles, M. R., McNoe, L. A., & Harbord, M. (2000). Aortic dissection patent ductus arteriosus, iris hypoplasia and brachytelephalangy in a male adolescent. Clinical Dysmorphology, 8, 269-276.

Journal - Research Article