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Authored Book - Research

Darlington, C. L. (2002). The Female Brain. London: Taylor and Francis, 211p.

Smith, P. F. (2002). Cannabis on the Brain. Palmerston North: Dunmore Press, 228p.

Smith, P. F., & Darlington, C. L. (1996). Clinical Psychopharmacology: A Primer. New York: Lawrence Erlbaum Associates, 143p.

Edited Book - Other

Sinclair, N., & Smith, N. A. (Eds.). (2003). 2003 healthcare handbook, incorporating the OTC Medicines Guide. Auckland: MediMedia.

Chapter in Book - Research

Maggo, S. D. S., & Ashton, J. C. (2015). Statins and the brain: Good, bad or both? In E. R. Travers (Ed.), Statins: Medical uses, mechanisms of action and clinical outcomes. (pp. 81-104). Nova Science.

Vidal, P. P., Cullen, K., Curthoys, I. S., Du Lac, S., Holstein, G., Idoux, E., … Smith, P. (2015). The vestibular system. In G. Paxinos (Ed.), The rat nervous system. (4th ed.) (pp. 805-864). London, UK: Academic Press. doi: 10.1016/B978-0-12-374245-2.00028-0

Nehoff, H., Parayath, N. N., Taurin, S., & Greish, K. (2014). In vivo evaluation of acute and chronic nanotoxicity. In S. C. Sahu & D. A. Casciano (Eds.), Handbook of nanotoxicology, nanomedicine and stem cell use in toxicology. (pp. 65-85). Chichester, UK: John Wiley & Sons. doi: 10.1002/9781118856017.ch3

Sundararajan, V., Rosengren, R. J., & Greish, K. (2014). Curcumin analogues for the treatment of breast cancer revisited: The nanotechnology approach. In D. L. Pouliquen (Ed.), Curcumin: Synthesis, emerging role in pain management and health implications. (pp. 347-378). Nova Science.

Nehoff, H., Taurin, S., & Greish, K. (2013). Toxicological assessment of nanomedicine. In Y. Yeo (Ed.), Nanoparticulate drug delivery systems: Strategies, technologies, and applications. (pp. 281-305). Hoboken, NJ: John Wiley & Sons.

Rivers, J. R., & Ashton, J. C. (2013). Neonatal asphyxia and stroke: Morbidity, models, consequences, and treatments. In D. Vordermark (Ed.), Hypoxia: Causes, types and management. (pp. 89-110). New York: Nova.

Taurin, S., & Greish, K. (2013). Enhanced vascular permeability in solid tumors: A promise for anticancer nanomedicine. In T. A. Martin & W. G. Jiang (Eds.), Cancer Metastasis: Biology and treatment (Vol. 19): Tight junctions in cancer metastasis. (pp. 81-118). Netherlands: Springer. doi: 10.1007/978-94-007-6028-8_4

Taurin, S., Nehoff, H., van Aswegen, T., & Greish, K. (2013). Tumor vasculature, EPR effect, and anticancer nanomedicine: Connecting the dots. In Y. H. Bae, R. J. Randall & K. Park (Eds.), Cancer targeted drug delivery: An elusive dream. (pp. 207-239). New York: Springer. doi: 10.1007/978-1-4614-7876-8_8

Greish, K., Thiagarajan, G., & Ghandehari, H. (2012). In vivo methods of nanotoxicology. In J. Reineke (Ed.), Nanotoxicity: Methods and protocols: Methods in molecular biology (Vol. 926). (pp. 235-253). New York: Springer. doi: 10.1007/978-1-62703-002-1_17

Dzeyk, J., Yadav, B., & Rosengren, R. J. (2011). Experimental therapeutics for the treatment of triple negative breast cancer. In E. Gunduz & M. Gunduz (Eds.), Breast cancer: Current and alternative therapeutic modalities. (pp. 371-394). Rijeka, Croatia: InTech.

Smith, P. F. (2011). The endocannabinoid system in the cochlear nucleus and its implications for tinnitus treatment. In A. R. Møller, B. Langguth, D. De Ridder & T. Kleinjung (Eds.), Textbook of tinnitus. (pp. 639-647). New York: Springer. doi: 10.1007/978-1-60761-145-5_79

Darlington, C. L., Zheng, Y., & Smith, P. F. (2009). Herbal medicinal products for tinnitus: Perspectives and evaluation. In P. Houghton & P. K. Mukherjee (Eds.), Evaluation of herbal medicinal products. (pp. 314-321). London: Pharmaceutical Press.

Giles, G. I. (2009). Redox-controlled transcription factors and gene expression. In C. Jacob & P. G. Winyard (Eds.), Redox signaling and regulation in biology and medicine. (pp. 245-270). Weinheim, Germany: Wiley-VCH.

Kerr, D. S. (2009). Domoic acid neurotoxicity. In M. D. Biner, N. Hirokawa & U. Windhorst (Eds.), Encyclopedia of neuroscience. (pp. 990-995). Berlin, Germany: Springer.

Rosengren, R. J. (2009). Utility of epigallocatechin gallate in the treatment and prevention of breast cancer: Molecular mechanisms for tumor suppression. In H. McKinley & M. Jamieson (Eds.), Handbook of green tea and health research. (pp. 301-323). New York: Nova.

Smith, P. F., Darlington, C. L., & Zheng, Y. (2009). Cognitive deficits following complete bilateral loss of vestibular function and their relationship to the hippocampus. In A. Lindqvist & G. Nyman (Eds.), Dizziness: Vertigo, disequilibrium and lightheadedness. New York: Nova Science.

Ashton, J. C., & Glass, M. (2008). Multiple roles for cannabinoids in neuroprotection during oxidative stress injury. In O. M. Roux (Ed.), Brain hypoxia-ischemia research progress. (pp. 229-244). New York: Nova.

Teng, X., Isbell, T. S., Crawford, J. H., Bosworth, C. A., Giles, G. I., Koenitzer, J. R., … Patel, R. P. (2008). Novel method for measuring S-nitrosothiols using hydrogen sulfide. In Methods in enzymology (Volo. 441: Nitric oxide, part G oxidative and nitrasative stress in redox regulation of cell signaling). (pp. 161-172). San Diego, CA: Academic Press. doi: 10.1016/s0076-6879(08)01209-3

Ashton, J. C. (2007). Oxidative stress induces upregulation of the CB2 receptor in a population of cells in the dentate gyrus subgranular layer. In S. G. Pandalai (Ed.), Recent Research Developments in Neuroscience (Vol. 2). (pp. 111-114). Trivandrum, India: Research Signpost.

Ashton, J. C., & Smith, P. F. (2007). Bcl-2 and mitochondrial control of apoptosis as a mechanism for regulating neural plasticity. In L. B. Shultz (Ed.), Cell Apoptosis: Regulation and Environmental Factors. (pp. 1-23). New York: Nova Science.

Clarkson, A. N., & Appleton, I. (2007). Cerebral hypoxia-ischemia-induced neuronal and cardiac impairment. In C. Kaur (Ed.), Hypoxia and the central nervous system. (pp. 109-144). Trivandrum, India: Transworld Research Network.

Smith, P. F., Zheng, Y., Goddard, M., & Darlington, C. L. (2007). Cognitive impairment due to inner ear damage. In H. C. Sentowski (Ed.), Cognitive Disorders Research Trends. (pp. 231-243). New York: Nova Science.

Coulter, D., Clark, D., Zhou, L., Ashton, J., & Harrison-Woolrych, M. (2006). Safety monitoring of celecoxib and rofecoxib in the New Zealand Intensive Medicines Monitoring Programme. In M. J. Howardell (Ed.), Trends in COX-2 inhibitor research. (pp. 105-135). New York: Nova Science.

Lees, G., Coyne, L., & Maddison, K. M. (2006). Ion channels. In H. F. Galley (Ed.), Anaesthesia science. (pp. 90-102). Malden, USA: Blackwell Publishing.

Smith, P. F. (2005). Cannabis and cannabinoids for the symptomatic treatment of multiple sclerosis. In F. Columbus (Ed.), Treatment and management of multiple sclerosis. (pp. 155-167). New York, NY: Nova Science Publishers.

Smith, P. F. (2005). Medicinal use of cannabis: Implications for lung cancer. In R. L. Carafaro (Ed.), Focus on lung cancer research. (pp. 193-209). New York, NY: Nova Science Publishers.

Rosengren, R. J., & Bray, B. J. (2003). Dietary retinol as a toxic substance. In Reviews in food and nutrition toxicity. (pp. 88-120). London: Taylor and Francis.

Temple, W. A., & Smith, N. A. (2001). Chapter 1. Basic pharmacology. In G. Park & M. Shelley (Eds.), Fundamentals of Anaesthesia and Acute Medicine Series. Pharmacology in the Critically ill: General Principles. (pp. 1-15). London: British Medical Journal Books.

Smith, P. F., & Darlington, C. L. (2000). The contributions of excitatory and inhibitory amino acid neurotransmitters to vestibular plasticity. In A. J. Beitz & J. H. Anderson (Eds.), Neurochemistry of the Vestibular System. (pp. 381-401). New York: CRC Press.

Darlington, C. L., Smith, P. F., & Maclennan, K. M. (1999). The neuroprotective properties of ginkgo extracts. In T. A. Van Beek (Ed.), Medicinal and Aromatic Plants - Industrial Profiles: Ginkgo Biloba. (pp. 331-344). Amsterdam: Harwood Academic Publishers.

Rose, J. C., Schwartz, J., Green, J., & Kerr, D. R. (1998). Development of the Corticotropin-Releasing Factor Adrenocorticotropic Hormone/Beta-Endorphin System in the Mammalian Fetus. In R. Polin & W. Fox (Eds.), Fetal and Neonatal Physiology. (pp. 2431-2442). Philadelphia, London: WB Saunders.

Smith, P. F., & Darlington, C. L. (1998). Neural mechanisms of psychiatric disturbances in patients with epilepsy. In H. McDonnell & P. Snyder (Eds.), Psychiatric co-morbidity in epilepsy: Basic mechanisms, diagnosis and treatment. (pp. 15-35). Washington DC: American Psychiatric Press.

Darlington, C. L., Smith, P. F., & Maclennan, K. M. (1997). Effects of Ginkgo biloba extract (EGb 761) on recovery from peripheral vestibular deafferentation (vestibular compensation). In V. Papadopoulos, K. Drieu & Y. Christen (Eds.), Advances in Ginkgo biloba Research, Vol. 6. (pp. 47-58). Paris: Elsevier.

Darlington, C., & Smith, P. (1996). What neurotransmitters are important in the vestibular system? In R. Baloh & G. M. Halmagyi (Eds.), Disorders of the Vestibular System. (pp. 140-144). New York: Oxford University Press.

Rathbone, M., Purves, R. D., Ghazali, F., & Ho, P. C. (1996). In vivo techniques for studying the oral mucosal absorption characteristics of drugs in animals and humans. In M. J. Rathbone (Ed.), Oral Mucosal Drug Delivery. (pp. 121-156). New York: Dekker.

Journal - Research Article

Aitken, P., Benoit, A., Zheng, Y., Philoxene, B., Le Gall, A., Denise, P., … Smith, P. F. (2016). Hippocampal and striatal M1-muscarinic acetylcholine receptors are down-regulated following bilateral vestibular loss in rats. Hippocampus, 26(12), 1509-1514. doi: 10.1002/hipo.22651

Alimoradi, H., Matikonda, S. S., Gamble, A. B., Giles, G. I., & Greish, K. (2016). Hypoxia responsive drug delivery systems in tumor therapy. Current Pharmaceutical Design, 22(19), 2808-2820.

Archibald, M., Pritchard, T., Nehoff, H., Rosengren, R. J., Greish, K., & Taurin, S. (2016). A combination of sorafenib and nilotinib reduces the growth of castrate-resistant prostate cancer. International Journal of Nanomedicine, 11, 179-201. doi: 10.2147/ijn.s97286

Badart, M. P., Squires, C. M. L., Baird, S. K., & Hawkins, B. C. (2016). The synthesis of clavatadine C. Tetrahedron Letters, 57(46), 5108-5111. doi: 10.1016/j.tetlet.2016.10.019

Balabhadrapatruni, S., Zheng, Y., Napper, R., & Smith, P. F. (2016). Basal dendritic length is reduced in the rat hippocampus following bilateral vestibular deafferentation. Neurobiology of Learning & Memory, 131, 56-60. doi: 10.1016/j.nlm.2016.03.009

Barzegar-Fallah, N., Baery, N., Soleymankhani, M., Malekmohammadi, N., Alimoradi, H., Parsa, A., & Barzegar-Fallah, A. (2016). Kelussia odoratissima Mozaff attenuates thromboembolic brain injury, possibly due to its Z-ligustilide content. Brain Injury, 30(7), 926-932. doi: 10.3109/02699052.2016.1144083

Hitier, M., Sato, G., Zhang, Y.-f., Zheng, Y., Besnard, S., Smith, P. F., & Curthoys, I. S. (2016). Anatomy and surgical approach of rat’s vestibular sensors and nerves. Journal of Neuroscience Methods, 270, 1-8. doi: 10.1016/j.jneumeth.2016.05.013

McKay, A. P., Lo, W. K. C., Preston, D., Giles, G. I., Crowley, J. D., Barnsley, J. E., Gordon, K. C., & McMorran, D. A. (2016). Palladium(II) and platinum(II) complexes of ((2-pyridyl)pyrazol-1-ylmethyl)benzoic acids: Synthesis, solid state characterisation and biological cytotoxicity. Inorganica Chimica Acta, 446, 41-53. doi: 10.1016/j.ica.2016.02.038

Milne, M., & Ashton, J. C. (2016). Effect of cannabinoids on CGRP release in the isolated rat lumbar spinal cord. Neuroscience Letters, 614, 39-42. doi: 10.1016/j.neulet.2015.12.060

Parayath, N. N., Nehoff, H., Norton, S. E., Highton, A. J., Taurin, S., Kemp, R. A., & Greish, K. (2016). Styrene maleic acid-encapsulated paclitaxel micelles: Antitumor activity and toxicity studies following oral administration in a murine orthotopic colon cancer model. International Journal of Nanomedicine, 11, 3979-3991. doi: 10.2147/IJN.S110251

Preston, D., McNeill, S. M., Lewis, J. E. M., Giles, G. I., & Crowley, J. D. (2016). Enhanced kinetic stability of [Pd2L4] 4+ cages through ligand substitution. Dalton Transactions, 45, 8050-8060. doi: 10.1039/c6dt00133e

Pritchard, T., Rosengren, R. J., Greish, K., & Taurin, S. (2016). Raloxifene nanomicelles reduce the growth of castrate-resistant prostate cancer. Journal of Drug Targeting, 24(5), 441-449. doi: 10.3109/1061186x.2015.1086360

Saisyo, A., Nakamura, H., Fang, J., Tsukigawa, K., Greish, K., Furukawa, H., & Maeda, H. (2016). pH-sensitive polymeric cisplatin-ion complex with styrene-maleic acid copolymer exhibits tumor-selective drug delivery and antitumor activity as a result of the enhanced permeability and retention effect. Colloids & Surfaces B, 138, 128-137. doi: 10.1016/j.colsurfb.2015.11.032

Smith, P. F. (2016). Age-related neurochemical changes in the vestibular nuclei. Frontiers in Neurology, 7, 20. doi: 10.3389/fneur.2016.00020

Smith, P. F., & Zheng, Y. (2016). Cannabinoids, cannabinoid receptors and tinnitus. Hearing Research, 332, 210-216. doi: 10.1016/j.heares.2015.09.014

Smith, P. F., Renner, R. M., & Haslett, S. J. (2016). Compositional data in neuroscience: If you've got it, log it! Journal of Neuroscience Methods, 271, 154-159. doi: 10.1016/j.jneumeth.2016.07.008

Taurin, S., Nimick, M., Larsen, L., & Rosengren, R. J. (2016). A novel curcumin derivative increases the cytotoxicity of raloxifene in estrogen receptor-negative breast cancer cell lines. International Journal of Oncology, 48, 385-398. doi: 10.3892/ijo.2015.3252

Tranter-Entwistle, I., Dawes, P., Darlington, C. L., Smith, P. F., & Cutfield, N. (2016). Video head impulse in comparison to caloric testing in unilateral vestibular schwannoma. Acta Oto-Laryngologica, 136(11), 1110-1114. doi: 10.1080/00016489.2016.1185540

Zadehvakili, B., McNeill, S. M., Fawcett, J. P., & Giles, G. I. (2016). The design of redox active thiol peroxidase mimics: Dihydrolipoic acid recognition correlates with cytotoxicity and prooxidant action. Biochemical Pharmacology, 104, 19-28. doi: 10.1016/j.bcp.2016.01.012

Baird, S. K. (2015). Mesenchymal stem cells: How can we realize their therapeutic potential in cancer therapy? Journal of Clinical & Experimental Pathology, 5(1), 206. doi: 10.4172/2161-0681.1000206

Baird, S. K., Allan, L., Renner, C., Scott, F. E., & Scott, A. M. (2015). Fibroblast activation protein increases metastatic potential of fibrosarcoma line HT1080 through upregulation of integrin-mediated signaling pathways. Clinical & Experimental Metastasis, 32(5), 507-516. doi: 10.1007/s10585-015-9723-4

Baird, S. K., Rigopoulos, A., Cao, D., Allan, L., Renner, C., Scott, F. E., & Scott, A. M. (2015). Integral membrane protease fibroblast activation protein sensitizes fibrosarcoma to chemotherapy and alters cell death mechanisms. Apoptosis, 20(11), 1483-1498. doi: 10.1007/s10495-015-1166-5

Barzegar-Fallah, A., Alimoradi, H., Asadi, F., Dehpour, A. R., Asgari, M., & Shafiei, M. (2015). Tropisetron ameliorates early diabetic nephropathy in streptozotocin-induced diabetic rats. Clinical & Experimental Pharmacology & Physiology, 42(4), 361-368. doi: 10.1111/1440-1681.12373

Barzegar-Fallah, A., Alimoradi, H., Razmi, A., Dehpour, A. R., Asgari, M., & Shafiei, M. (2015). Inhibition of calcineurin/NFAT pathway plays an essential role in renoprotective effect of tropisetron in early stage of diabetic nephropathy. European Journal of Pharmacology, 767, 152-159. doi: 10.1016/j.ejphar.2015.10.019

Clarke, M. R., Imhoff, F. M., & Baird, S. K. (2015). Mesenchymal stem cells inhibit breast cancer cell migration and invasion through secretion of tissue inhibitor of metalloproteinase-1 and -2. Molecular Carcinogenesis, 54(10), 1214-1219. doi: 10.1002/mc.22178

Cridge, B. J., & Cridge, A. G. (2015). Evaluating how universities engage school students with science: A model based on the analysis of the literature. Australian Universities' Review, 57(1), 34-44.

Daruwalla, J., Greish, K., Malcontenti-Wilson, C., Muralidharan, V., Maeda, H., & Christophi, C. (2015). Styrene maleic acid copolymer—pirarubicin induces tumor-selective oxidative stress and decreases tumor hypoxia as possible treatment of colorectal cancer liver metastases. Surgery, 158(1), 236-247. doi: 10.1016/j.surg.2015.03.019

Gliddon, C. M., & Cridge, B. (2015). Psychoactive Substances Bill and Act of New Zealand: A chance to engage undergraduate scientists with society using a transfer learning paradigm. Journal of Undergraduate Neuroscience Education, 14(1), A1-A7.

Hellyer, S. D., Indurthi, D., Balle, T., Runder-Varga, V., Selwood, A. I., Tyndall, J. D. A., … Kerr, D. S. (2015). Pinnatoxins E, F and G target multiple nicotinic receptor subtypes. Journal of Neurochemistry, 135(3), 479-491. doi: 10.1111/jnc.13245

Hitier, M., Hamon, M., Denise, P., Lacoudre, J., Thenint, M.-A., Mallet, J.-F., … Quarck, G. (2015). Lateral semicircular canal asymmetry in idiopathic scoliosis: An early link between biomechanical, hormonal and neurosensory theories? PLoS ONE, 10(7), e0131120. doi: 10.1371/journal.pone.0131120

Lamb, R. A., Badart, M. P., Swaney, B. E., Gai, S., Baird, S. K., & Hawkins, B. C. (2015). The synthesis and biological evaluation of anithiactin A/thiasporine C and analogues. Australian Journal of Chemistry, 68(12), 1829-1833. doi: 10.1071/CH15461

Lei, J., Burgess, E. J., Richardson, A. T. B., Hawkins, B. C., Baird, S. K., Smallfield, B. M., van Klink, J. W., & Perry, N. B. (2015). Cytotoxic amides from fruits of kawakawa, Macropiper excelsum. Planta Medica, 81, 1163-1168. doi: 10.1055/s-0035-1546106

Linsell, O., Brownjohn, P. W., Nehoff, H., Greish, K., & Ashton, J. C. (2015). Effect of styrene maleic acid WIN55,212-2 micelles on neuropathic pain in a rat model. Journal of Drug Targeting, 23(4), 353-359. doi: 10.3109/1061186x.2014.997737

Lo, W. K. C., Huff, G. S., Preston, D., McMorran, D. A., Giles, G. I., Gordon, K. C., & Crowley, J. D. (2015). A dinuclear platinum(II) N4Py complex: An unexpected coordination mode for N4Py. Inorganic Chemistry, 54(14), 6671-6673. doi: 10.1021/acs.inorgchem.5b01032

McNeill, S. M., Preston, D., Lewis, J. E. M., Robert, A., Knerr-Rupp, K., Graham, D. O., Wright, J. R., Giles, G. I., & Crowley, J. D. (2015). Biologically active [Pd2L4]4+ quadruply-stranded helicates: Stability and cytotoxicity. Dalton Transactions, 44, 11129-11136. doi: 10.1039/c5dt01259g

Nayak, P. K., & Kerr, D. S. (2015). Functional preservation of hippocampal CA1 by low-dose GYKI-52466 preconditioning in a rat model of hypoxic-ischemic brain injury. Brain Research, 1613, 100-109. doi: 10.1016/j.brainres.2015.04.004

Nehoff, H., Parayath, N. N., McConnell, M. J., Taurin, S., & Greish, K. (2015). A combination of tyrosine kinase inhibitors, crizotinib and dasatinib for the treatment of glioblastoma multiforme. Oncotarget, 6(35), 37948-37964. doi: 10.18632/oncotarget.5698

Parayath, N. N., Nehoff, H., Müller, P., Taurin, S., & Greish, K. (2015). Styrene maleic acid micelles as a nanocarrier system for oral anticancer drug delivery: Dual uptake through enterocytes and M-cells. International Journal of Nanomedicine, 10, 4653-4667. doi: 10.2147/ijn.s87681

Read, M. I., Harrison, J. C., Kerr, D. S., & Sammut, I. A. (2015). Atenolol offers better protection than clonidine against cardiac injury in kainic acid-induced status epilepticus. British Journal of Pharmacology, 172, 4626-4638. doi: 10.1111/bph.13132

Read, M. I., McCann, D. M., Millen, R. N., Harrison, J. C., Kerr, D. S., & Sammut, I. A. (2015). Progressive development of cardiomyopathy following altered autonomic activity in status epilepticus. American Journal of Physiology: Heart & Circulatory Physiology, 309(9), H1554-H1564. doi: 10.1152/ajpheart.00256.2015

Revalde, J. L., Li, Y., Hawkins, B. C., Rosengren, R. J., & Paxton, J. W. (2015). Heterocyclic cyclohexanone monocarbonyl analogues of curcumin can inhibit the activity of ATP-binding cassette transporters in cancer multidrug resistance. Biochemical Pharmacology, 93(3), 305-317. doi: 10.1016/j.bcp.2014.12.012

Salerno, S., Pittalà, V., Romeo, G., Modica, M. N., Marrazzo, A., Siracusa, M. A., … Greish, K. (2015). Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines. European Journal of Medicinal Chemistry, 96, 162-172. doi: 10.1016/j.ejmech.2015.04.003

Stiles, L., & Smith, P. F. (2015). The vestibular-basal ganglia connection: Balancing motor control. Brain Research, 1597, 180-188. doi: 10.1016/j.brainres.2014.11.063

Thaung, H. P. A., Yao, Y., Bussey, C. T., Hughes, G., Jones, P. P., Bahn, A., Sammut, I. A., & Lamberts, R. R. (2015). Chronic bilateral renal denervation reduces cardiac hypertrophic remodelling but not β-adrenergic responsiveness in hypertensive type 1 diabetic rats. Experimental Physiology, 100(6), 628-639. doi: 10.1113/EP085021

Tsukigawa, K., Liao, L., Nakamura, H., Fang, J., Greish, K., Otagiri, M., & Maeda, H. (2015). Synthesis and therapeutic effect of styrene—maleic acid copolymer-conjugated pirarubicin. Cancer Science, 106(3), 270-278. doi: 10.1111/cas.12592

Xian, S., Parayath, N. N., Nehoff, H., Giles, N. M., & Greish, K. (2015). The use of styrene maleic acid nanomicelles encapsulating the synthetic cannabinoid analog WIN55,212-2 for the treatment of cancer. Anticancer Research, 35(9), 4707-4712.

Zheng, Y., Dixon, S., McPherson, K., & Smith, P. F. (2015). Glutamic acid decarboxylase levels in the cochlear nucleus of rats with acoustic trauma-induced chronic tinnitus. Neuroscience Letters, 586, 60-64. doi: 10.1016/j.neulet.2014.11.047

Zheng, Y., McPherson, K., Reid, P., & Smith, P. F. (2015). The anti-inflammatory selective melanocortin receptor subtype 4 agonist, RO27-3225, fails to prevent acoustic trauma-induced tinnitus in rats. European Journal of Pharmacology, 761, 206-210. doi: 10.1016/j.ejphar.2015.05.007

Zheng, Y., Reid, P., & Smith, P. F. (2015). Cannabinoid CB1 receptor agonists do not decrease, but may increase, acoustic trauma-induced tinnitus in rats. Frontiers in Neurology, 6, 60. doi: 10.3389/fneur.2015.00060

Zheng, Y., Smithies, H., Aitken, P., Gliddon, C., Stiles, L., Darlington, C. L., & Smith, P. F. (2015). Cell proliferation in the cochlear nucleus following acoustic trauma in rat. Neuroscience, 303, 524-534. doi: 10.1016/j.neuroscience.2015.07.033

Baird, S. (2014). Mesenchymal stem cells in cancer therapy: Our chance to take charge. European Pharmaceutical Review, 19(2), 55-59.

Chiarovano, E., Darlington, C., Vidal, P.-P., Lamas, G., & de Waele, C. (2014). The role of cervical and ocular vestibular evoked myogenic potentials in the assessment of patients with vestibular schwannomas. PLoS ONE, 9(8), e105026. doi: 10.1371/journal.pone.0105026

De Wever, V., Nasa, I., Chamousset, D., Lloyd, D., Nimick, M., Trinkle-Mulcahy, L., … Moorhead, G. B. G. (2014). The human mitotic kinesin KIF18A binds protein phosphatase 1 (PP1) through a highly conserved docking motif. Biochemical & Biophysical Research Communications, 453(3), 432-437. doi: 10.1016/j.bbrc.2014.09.105

Garrett, A. T., Goosens, N. G., Rehrer, N. J., Patterson, M. J., Harrison, J., Sammut, I., & Cotter, J. D. (2014). Short-term heat acclimation is effective and may be enhanced rather than impaired by dehydration. American Journal of Human Biology, 26(3), 311-320. doi: 10.1002/ajhb.22509

Hellyer, S. D., Selwood, A. I., van Ginkel, R., Munday, R., Sheard, P., Miles, C. O., … Kerr, D. S. (2014). In vitro labelling of muscle type nicotinic receptors using a fluorophore-conjugated pinnatoxin F derivative. Toxicon, 87, 17-25. doi: 10.1016/j.toxicon.2014.05.013

Hitier, M., Barbier, C., Marie-Aude, T., Moreau, S., Courtheoux, P., & Patron, V. (2014). New treatment of vertigo caused by jugular bulb abnormalities. Surgical Innovation, 21(4), 365-371. doi: 10.1177/1553350613505918

Hitier, M., Besnard, S., & Smith, P. F. (2014). Vestibular pathways involved in cognition. Frontiers in Integrative Neuroscience, 8, 59. doi: 10.3389/fnint.2014.00059

Hosseini, S., Jamshidi, L., Mehrzadi, S., Mohammad, K., Najmizadeh, A. R., Alimoradi, H., & Huseini, H. F. (2014). Effects of Juglans regia L. leaf extract on hyperglycemia and lipid profiles in type two diabetic patients: A randomized double-blind, placebo-controlled clinical trial. Journal of Ethnopharmacology, 152(3), 451-456. doi: 10.1016/j.jep.2014.01.012

Kumari, S., Sammut, I. A., & Giles, G. I. (2014). The design of nitric oxide donor drugs: S-nitrosothiol tDodSNO is a superior photoactivated donor in comparison to GSNO and SNAP. European Journal of Pharmacology, 737, 168-176. doi: 10.1016/j.ejphar.2014.05.012

Linsell, O., & Ashton, J. C. (2014). Cerebral hypoxia-ischemia causes cardiac damage in a rat model. NeuroReport, 25(10), 796-800. doi: 10.1097/wnr.0000000000000190

MacDonald, C., Finlay, D. B., Jabed, A., Glass, M., & Graham, E. S. (2014). Development of positive control tissue for in situ hybridisation using Alvetex scaffolds. Journal of Neuroscience Methods, 238, 70-77. doi: 10.1016/j.jneumeth.2014.09.006

Maggo, S., & Ashton, J. C. (2014). Effects of HMG-CoA reductase inhibitors on learning and memory in the guinea pig. European Journal of Pharmacology, 723, 294-304. doi: 10.1016/j.ejphar.2013.11.018

Marchalant, Y., Brownjohn, P. W., Bonnet, A., Kleffmann, T., & Ashton, J. C. (2014). Validating antibodies to the cannabinoid CB2 receptor: Antibody sensitivity is not evidence of antibody specificity. Journal of Histochemistry & Cytochemistry, 62(6), 395-404. doi: 10.1369/0022155414530995

Mohamed, S., Parayath, N. N., Taurin, S., & Greish, K. (2014). Polymeric nano-micelles: Versatile platform for targeted delivery in cancer. Therapeutic Delivery, 5(10), 1101-1121. doi: 10.4155/tde.14.69

Nehoff, H., Parayath, N. N., Domanovitch, L., Taurin, S., & Greish, K. (2014). Nanomedicine for drug targeting: Strategies beyond the enhanced permeability and retention effect. International Journal of Nanomedicine, 9(1), 2539-2555. doi: 10.2147/IJN.S47129

Nehoff, H., Parayath, N. N., Taurin, S., & Greish, K. (2014). The influence of drug loading on caveolin-1 mediated intracellular internalization of doxorubicin nanomicelles in vitro. Journal of Nanomedicine & Nanotechnology, 5(2), 1000197. doi: 10.4172/2157-7439.1000197

Read, M. I., Andreianova, A. A., Harrison, J. C., Goulton, C. S., Sammut, I. A., & Kerr, D. S. (2014). Cardiac electrographic and morphological changes following status epilepticus: Effect of clonidine. Seizure, 23(1), 55-61. doi: 10.1016/j.seizure.2013.09.012

Rivers-Auty, J. R., Smith, P. F., & Ashton, J. C. (2014). The cannabinoid CB2 receptor agonist GW405833 does not ameliorate brain damage induced by hypoxia-ischemia in rats. Neuroscience Letters, 569, 104-109. doi: 10.1016/j.neulet.2014.03.077

Shahpoury, P., Hageman, K. J., Matthaei, C. D., Alumbaugh, R. E., & Cook, M. E. (2014). Increased concentrations of polycyclic aromatic hydrocarbons in alpine streams during annual snowmelt: Investigating effects of sampling method, site characteristics, and meteorology. Environmental Science & Technology, 48(19), 11294-11301. doi: 10.1021/es502999e

Shirazi, M., Alimoradi, H., Kheirandish, Y., Etemad-Moghadam, S., Alaeddini, M., Meysamie, A., … Dehpour, A. R. (2014). Pantoprazole, a proton pump inhibitor, increases orthodontic tooth movement in rats. Iranian Journal of Basic Medical Sciences, 17(6), 448-453.

Smith, P. F., & Zheng, Y. (2014). Cannabis, cannabinoids and tinnitus. Journal of Pharmacology & Drug Metabolism, 1, 1-6. Retrieved from http://www.jscholaronline.org/journals/journal-of-pharmacology-and-drug-metabolism/jhome.php

Smith, P. F., Darlington, C. L., & Zheng, Y. (2014). The effects of complete vestibular deafferentation on spatial memory and the hippocampus in rat: The Dunedin experience. Multisensory Research, 28(5-6), 461-485. doi: 10.1163/22134808-00002469

Taurin, S., Nehoff, H., van Aswegen, T., Rosengren, R. J., & Greish, K. (2014). A novel role for raloxifene nanomicelles in management of castrate resistant prostate cancer. BioMed Research International, 2014, 323594. doi: 10.1155/2014/323594

Tsenkina, Y., Ruzov, A., Gliddon, C., Horsburgh, K., & De Sousa, P. A. (2014). White matter tract and glial-associated changes in 5-hydroxymethylcytosine following chronic cerebral hypoperfusion. Brain Research, 1592, 82-100. doi: 10.1016/j.brainres.2014.09.060

Ulrich, K., Aitken, P. N., Abraham, W. C., Dalrymple-Alford, J. C., & McNaughton, N. (2014). Effects of thalamic lesions on repeated re-learning of a spatial working memory task. Behavioural Brain Research, 261, 56-59. doi: 10.1016/j.bbr.2013.12.002

Yao, Y., Fomison-Nurse, I. C., Harrison, J. C., Walker, R. J., Davis, G., & Sammut, I. A. (2014). Chronic bilateral renal denervation attenuates renal injury in a transgenic rat model of diabetic nephropathy. American Journal of Physiology: Renal Physiology, 307, F251-F262. doi: 10.1152/ajprenal.00578.2013

Zheng, Y., Geddes, L., Sato, G., Stiles, L., Darlington, C. L., & Smith, P. F. (2014). Galvanic vestibular stimulation impairs cell proliferation and neurogenesis in the rat hippocampus but not spatial memory. Hippocampus, 24(5), 541-552. doi: 10.1002/hipo.22247

Zheng, Y., McPherson, K., & Smith, P. F. (2014). Effects of early and late treatment with L-baclofen on the development and maintenance of tinnitus caused by acoustic trauma in rats. Neuroscience, 258, 410-421. doi: 10.1016/j.neuroscience.2013.11.032

Zheng, Y., Stiles, L., Chien, Y.-T., Darlington, C. L., & Smith, P. F. (2014). The effects of acute stress-induced sleep disturbance on acoustic trauma-induced tinnitus in rats. BioMed Research International, 2014, 724195. doi: 10.1155/2014/724195

Aitken, J. B., Shearer, E. L., Giles, N. M., Lai, B., Vogt, B., Reboucas, J. S., … Giles, G. I. (2013). Intracellular targeting and pharmacological activity of the superoxide dismutase mimics MnTE-2-PyP5+ and MnTnHex-2-PyP5+ regulated by their porphyrin ring substituents. Inorganic Chemistry, 52(8), 4121-4123. doi: 10.1021/ic300700g

Ashton, J. C. (2013). Phylogenetic methods in drug discovery. Current Drug Discovery Technologies, 10(4), 255-262. doi: 10.2174/15701638113109990033

Baek, J.-H., Darlington, C. L., Smith, P. F., & Ashton, J. C. (2013). Antibody testing for brain immunohistochemistry: Brain immunolabeling for the cannabinoid CB2 receptor. Journal of Neuroscience Methods, 216(2), 87-95. doi: 10.1016/j.jneumeth.2013.03.021

Bray, B. J., & Cridge, A. G. (2013). Can education programmes effect long term behavioural change? International Journal of Innovative Interdisciplinary Research, 2(2), 27-33.

Cridge, B. J., & Rosengren, R. J. (2013). Critical appraisal of the potential use of cannabinoids in cancer management. Cancer Management & Research, 5, 301-313. doi: 10.2147/CMAR.S36105

Cridge, B. J., Larsen, L., & Rosengren, R. J. (2013). Curcumin and its derivatives in breast cancer: Current developments and potential for the treatment of drug-resistant cancers. Oncology Discovery, 1(6). doi: 10.7243/2052-6199-1-6

Diwan, V., Mistry, A., Gobe, G., & Brown, L. (2013). Adenine-induced chronic kidney and cardiovascular damage in rats. Journal of Pharmacological & Toxicological Methods, 68(2), 197-207. doi: 10.1016/j.vascn.2013.05.006

Diwan, V., Poudyal, H., & Brown, L. (2013). Piperine attenuates cardiovascular, liver and metabolic changes in high carbohydrate, high fat-fed rats. Cell Biochemistry & Biophysics, 67(2), 297-304. doi: 10.1007/s12013-011-9306-1

Hellyer, S. D., Selwood, A. I., Rhodes, L., & Kerr, D. S. (2013). Neuromuscular blocking activity of pinnatoxins E, F and G. Toxicon, 76, 214-220. doi: 10.1016/j.toxicon.2013.10.009

Hitier, M., Zhang, M., Labrousse, M., Barbier, C., Patron, V., & Moreau, S. (2013). Persistent stapedial arteries in human: From phylogeny to surgical consequences. Surgical & Radiologic Anatomy, 35(10), 883-891. doi: 10.1007/s00276-013-1127-z

Nayak, P. K., & Kerr, D. S. (2013). Low-dose GYKI-52466: Prophylactic preconditioning confers long-term neuroprotection and functional recovery following hypoxic-ischaemic brain injury. Neuroscience, 232, 128-138. doi: 10.1016/j.neuroscience.2012.11.063

Nayak, P. K., Zhang, H., & Kerr, D. S. (2013). Determination of 1-(4’-aminophenyl)-4-methyl-7,8-methylene-dioxy-2,3-benzodiazepine by high-performance liquid chromatography—diode array detection in plasma and brain in healthy and hypoxic–ischaemic rats. Neuroscience, 232, 139-150. doi: 10.1016/j.neuroscience.2012.12.001

Rivers, J. R., & Ashton, J. C. (2013). Age matching animal models to humans: Theoretical considerations. Current Drug Discovery Technologies, 10(3), 177-181.

Skene-Arnold, T. D., Luu, H. A., Uhrig, R. G., De Wever, V., Nimick, M., Maynes, J., … Holmes, C. F. B. (2013). Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins. Biochemical Journal, 449(3), 649-659. doi: 10.1042/BJ20120506

Smith, P. F., & Zheng, Y. (2013). From ear to uncertainty: Vestibular contributions to cognitive function. Frontiers in Integrative Neuroscience, 7, 84. doi: 10.3389/fnint.2013.00084

Smith, P. F., & Zheng, Y. (2013). Principal component analysis suggests subtle changes in glutamate receptor subunit expression in the rat hippocampus following bilateral vestibular deafferentation. Neuroscience Letters, 548, 265-268. doi: 10.1016/j.neulet.2013.05.036

Smith, P. F., Ganesh, S., & Liu, P. (2013). A comparison of random forest regression and multiple linear regression for prediction in neuroscience. Journal of Neuroscience Methods, 220(1). doi: 10.1016/j.jneumeth.2013.08.024

Smith, P. F., Haslett, S., & Zheng, Y. (2013). A multivariate statistical and data mining analysis of spatial memory–related behaviour following bilateral vestibular loss in the rat. Behavioural Brain Research, 246, 15-23. doi: 10.1016/j.bbr.2013.02.033

Sutherland, B. A., Harrison, J. C., Nair, S. M., & Sammut, I. A. (2013). Inhalation gases or gaseous mediators as neuroprotectants for cerebral ischaemia. Current Drug Targets, 14(1), 56-73. doi: 10.2174/138945013804806433

Taurin, S., Allen, K. M., Scandlyn, M. J., & Rosengren, R. J. (2013). Raloxifene reduces triple-negative breast cancer tumor growth and decreases EGFR expression. International Journal of Oncology, 43(3), 785-792. doi: 10.3892/ijo.2013.2012

Taurin, S., Nehoff, H., Diong, J., Larsen, L., Rosengren, R. J., & Greish, K. (2013). Curcumin-derivative nanomicelles for the treatment of triple negative breast cancer. Journal of Drug Targeting, 21(7), 675-683. doi: 10.3109/1061186X.2013.796955

Thiagarajan, G., Greish, K., & Ghandehari, H. (2013). Charge affects the oral toxicity of poly(amidoamine) dendrimers. European Journal of Pharmaceutics & Biopharmaceutics, 84(2), 330-334. doi: 10.1016/j.ejpb.2013.01.019

Thiagarajan, G., Sadekar, S., Greish, K., Ray, A., & Ghandehari, H. (2013). Evidence of oral translocation of anionic G6.5 dendrimers in mice. Molecular Pharmaceutics, 10(3), 988-998. doi: 10.1021/mp300436c

Zheng, Y., Wilson, G., Stiles, L., & Smith, P. F. (2013). Glutamate receptor subunit and calmodulin kinase II expression, with and without T maze training, in the rat hippocampus following bilateral vestibular deafferentation. PLoS ONE, 8(2), e54527. doi: 10.1371/journal.pone.0054527

Aitken, J. B., Lay, P. A., Duong, T. T. H., Aran, R., Witting, P. K., Harris, H. H., … Giles, G. I. (2012). Synchrotron radiation induced X-ray emission studies of the antioxidant mechanism of the organoselenium drug ebselen. Journal of Biological Inorganic Chemistry, 17(4), 589-598. doi: 10.1007/s00775-012-0879-y

Ang, A. D., Konigstorfer, A., Giles, G. I., & Bhatia, M. (2012). Measuring free tissue sulfide. Advances in Biological Chemistry, 2(4), 360-365. doi: 10.4236/abc.2012.24044

Araújo, W. L., Tohge, T., Nunes-Nesi, A., Daloso, D. M., Nimick, M., Krahnert, I., … Fernie, A. R. (2012). Phosphonate analogs of 2-oxoglutarate perturb metabolism and gene expression in illuminated Arabidopsis leaves. Frontiers in Plant Science, 3, 114. doi: 10.3389/fpls.2012.00114

Ashton, J. C. (2012). Neuropathic pain: An evolutionary hypothesis. Medical Hypotheses, 78(5), 641-643. doi: 10.1016/j.mehy.2012.01.044

Ashton, J. C. (2012). Synthetic cannabinoids as drugs of abuse. Current Drug Abuse Reviews, 5(2), 158-168. doi: 10.2174/1874473711205020158

Ashton, J. C. (2012). The atypical cannabinoid O-1602: Targets, actions, and the central nervous system. Central Nervous System Agents in Medicinal Chemistry, 12(3), 233-239.

Breen, C., Brownjohn, P. W., & Ashton, J. C. (2012). The atypical cannabinoid O-1602 increases hind paw sensitisation in the chronic constriction injury model of neuropathic pain. Neuroscience Letters, 508(2), 119-122. doi: 10.1016/j.neulet.2011.12.039

Brownjohn, P. W., & Ashton, J. C. (2012). Spinal cannabinoid CB2 receptors as a target for neuropathic pain: An investigation using chronic constriction injury. Neuroscience, 203, 180-193. doi: 10.1016/j.neuroscience.2011.12.028

De Wever, V., Lloyd, D. C., Nasa, I., Nimick, M., Trinkle-Mulcahy, L., Gourlay, R., … Moorhead, G. B. G. (2012). Isolation of human mitotic protein phosphatase complexes: Identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21. PLoS ONE, 7(6), e39510. doi: 10.1371/journal.pone.0039510

Fang, J., Greish, K., Qin, H., Liao, L., Nakamura, H., Takeya, M., & Maeda, H. (2012). HSP32 (HO-1) inhibitor, copoly(styrene-maleic acid)-zinc protoporphyrin IX, a water-soluble micelle as anticancer agent: In vitro and in vivo anticancer effect. European Journal of Pharmaceutics & Biopharmaceutics, 81, 540-547. doi: 10.1016/j.ejpb.2012.04.016

Gandhy, S. U., Kim, K., Larsen, L., Rosengren, R. J., & Safe, S. (2012). Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting MicroRNAs. BMC Cancer, 12(1), 564. doi: 10.1186/1471-2407-12-564

Giles, N. M., Kumari, S., Gang, B. P., Yuen, C. W. W., Billaud, E. M. F., & Giles, G. I. (2012). The molecular design of S-nitrosothiols as photodynamic agents for controlled nitric oxide release. Chemical Biology & Drug Design, 80(3), 471-478. doi: 10.1111/j.1747-0285.2012.01420.x

Giles, N. M., Kumari, S., Stamm, R., Patel, S., & Giles, G. I. (2012). A hydrogen peroxide electrode assay to measure thiol peroxidase activity for organoselenium and organotellurium drugs. Analytical Biochemistry, 429(2), 103-107. doi: 10.1016/j.ab.2012.07.013

Greish, K. (2012). Enhanced permeability and retention effect for selective targeting of anticancer nanomedicine: Are we there yet? Drug Discovery Today: Technologies, 9(2), e161-e166. doi: 10.1016/j.ddtec.2011.11.010

Greish, K., Thiagarajan, G., Herd, H., Price, R., Bauer, H., Hubbard, D., … Ghandehari, H. (2012). Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles. Nanotoxicology, 6(7), 713-723. doi: 10.3109/17435390.2011.604442

Harrison-Woolrych, M., Härmark, L., Tan, M., Maggo, S., & van Grootheest, K. (2012). Epistaxis and other haemorrhagic events associated with the smoking cessation medicine varenicline: A case series from two national pharmacovigilance centres. European Journal of Clinical Pharmacology, 68, 1065-1072. doi: 10.1007/s00228-012-1220-y

Harrison-Woolrych, M., Maggo, S., Tan, M., Savage, R., & Ashton, J. (2012). Cardiovascular events in patients taking varenicline: A case series from intensive postmarketing surveillance in New Zealand. Drug Safety, 35(1), 33-43. doi: 10.2165/11597690-000000000-00000

James, R., Searcy, J. L., Le Bihan, T., Martin, S. F., Gliddon, C. M., Povey, J., … Horsburgh, K. (2012). Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge. Journal of Cerebral Blood Flow & Metabolism, 32, 164-176. doi: 10.1038/jcbfm.2011.120

Leung, E., Rewcastle, G. W., Joseph, W. R., Rosengren, R. J., Larsen, L., & Baguley, B. C. (2012). Identification of cyclohexanone derivatives that act as catalytic inhibitors of topoisomerase I: Effects on tamoxifen-resistant MCF-7 cancer cells. Investigational New Drugs, 30, 2103-2112. doi: 10.1007/s10637-011-9768-4

Maggo, S., Clark, D., & Ashton, J. C. (2012). The effect of statins on performance in the Morris water maze in guinea pig. European Journal of Pharmacology, 674(2-3), 287-293. doi: 10.1016/j.ejphar.2011.11.006

Mandhane, S., Nayak, P., Soni, D., Jain, S., Ashton, J. C., & Rajamannar, T. (2012). Induction of glucose intolerance by acute administration of rimonabant. Pharmacology, 89(5-6), 339-347. doi: 10.1159/000337731

Nair, S. M., Mishra, P., Norris, P. T., & Paul, C. (2012). The destination of Pacific Island health professional graduates from a New Zealand university. Human Resources for Health, 10(24). doi: 10.1186/1478-4491-10-24

Neo, P., Carter, D., Zheng, Y., Smith, P., Darlington, C., & McNaughton, N. (2012). Septal elicitation of hippocampal theta rhythm did not repair cognitive and emotional deficits resulting from vestibular lesions. Hippocampus, 22(5), 1176-1187. doi: 10.1002/hipo.20963

Price, R., Gustafson, J., Greish, K., Cappello, J., McGill, L., & Ghandehari, H. (2012). Comparison of silk-elastinlike protein polymer hydrogel and poloxamer in matrix-mediated gene delivery. International Journal of Pharmaceutics, 427(1), 97-104. doi: 10.1016/j.ijpharm.2011.09.037

Rivers, J. R., Maggo, S. D. S., & Ashton, J. C. (2012). Neuroprotective effect of hydroxypropyl-β-cyclodextrin in hypoxia-ischemia. NeuroReport, 23(3), 134-138. doi: 10.1097/WNR.0b013e32834ee47c

Smith, P. F. (2012). Dyscalculia and vestibular function. Medical Hypotheses, 79(4), 493-496. doi: 10.1016/j.mehy.2012.06.032

Stadler, N., Heeneman, S., Vöö, S., Stanley, N., Giles, G. I., Gang, B. P., … Davies, M. J. (2012). Reduced metal ion concentrations in atherosclerotic plaques from subjects with Type 2 diabetes mellitus. Atherosclerosis, 222(2), 512-518. doi: 10.1016/j.atherosclerosis.2012.03.015

Stiles, L., Zheng, Y., Darlington, C. L., & Smith, P. F. (2012). The D2 dopamine receptor and locomotor hyperactivity following bilateral vestibular deafferentation in the rat. Behavioural Brain Research, 227(1), 150-158. doi: 10.1016/j.bbr.2011.11.006

Stiles, L., Zheng, Y., Darlington, C. L., & Smith, P. F. (2012). The effects of the D2 dopamine receptor antagonist, eticlopride, on attention following bilateral vestibular deafferentation in the rat. Neuroscience Letters, 506(2), 193-197. doi: 10.1016/j.neulet.2011.11.003

Tran, H. T., Nimick, M., Uhrig, R. G., Templeton, G., Morrice, N., Gourlay, R., … Moorhead, G. B. G. (2012). Arabidopsis thaliana histone deacetylase 14 (HDA14) is an α-tubulin deacetylase that associates with PP2A and enriches in the microtubule fraction with the putative histone acetyltransferase ELP3. Plant Journal, 71(2), 263-272. doi: 10.1111/j.1365-313X.2012.04984.x

Winburn, I. C., Gunatunga, K., McKernan, R. D., Walker, R. J., Sammut, I. A., & Harrison, J. C. (2012). Cell damage following carbon monoxide releasing molecule exposure: Implications for therapeutic applications. Basic & Clinical Pharmacology & Toxicology, 111(1), 31-41. doi: 10.1111/j.1742-7843.2012.00856.x

Yadav, B., Taurin, S., Larsen, L., & Rosengren, R. J. (2012). RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ERnegative breast cancer models. International Journal of Oncology, 41(5), 1723-1732. doi: 10.3892/ijo.2012.1625

Yadav, B., Taurin, S., Larsen, L., & Rosengren, R. J. (2012). RL71, a second-generation curcumin analog, induces apoptosis and downregulates Akt in ER-negative breast cancer cells. International Journal of Oncology, 41(3), 1119-1127. doi: 10.3892/ijo.2012.1521

Yu, T., Greish, K., McGill, L. D., Ray, A., & Ghandehari, H. (2012). Influence of geometry, porosity, and surface characteristics of silica nanoparticles on acute toxicity: Their vasculature effect and tolerance threshold. ACS Nano, 6(3), 2289-2301. doi: 10.1021/nn2043803

Zadehvakili, B., Fawcett, J. P., & Giles, G. I. (2012). Synthesis, structure activity relationship studies and antioxidant activity evaluation of some organochalcogen catalysts as novel GPx mimics. Free Radical Biology & Medicine, 53(Suppl. 1), S99. doi: 10.1016/j.freeradbiomed.2012.08.206

Zheng, Y., Balabhadrapatruni, S., Baek, J. H., Chung, P., Gliddon, C., Zhang, M., Darlington, C. L., Napper, R., … Smith, P. F. (2012). The effects of bilateral vestibular loss on hippocampal volume, neuronal number, and cell proliferation in rats. Frontiers in Neurology, 3, 20. doi: 10.3389/fneur.2012.00020

Zheng, Y., Cheung, I., & Smith, P. F. (2012). Performance in anxiety and spatial memory tests following bilateral vestibular loss in the rat and effects of anxiolytic and anxiogenic drugs. Behavioural Brain Research, 235(1), 21-29. doi: 10.1016/j.bbr.2012.07.025

Zheng, Y., McNamara, E., Stiles, L., Darlington, C. L., & Smith, P. F. (2012). Evidence that memantine reduces chronic tinnitus caused by acoustic trauma in rats. Frontiers in Neurology, 3, 127. doi: 10.3389/fneur.2012.00127

Zheng, Y., Vagal, S., McNamara, E., Darlington, C. L., & Smith, P. F. (2012). A dose–response analysis of the effects of L-baclofen on chronic tinnitus caused by acoustic trauma in rats. Neuropharmacology, 62, 940-946. doi: 10.1016/j.neuropharm.2011.09.027

Baek, J. H., Zheng, Y., Darlington, C. L., & Smith, P. F. (2011). Cannabinoid CB1 receptor expression and affinity in the rat hippocampus following bilateral vestibular deafferentation. Neuroscience Letters, 487(3), 330-334. doi: 10.1016/j.neulet.2010.10.050

Errington, A. C., & Connelly, W. M. (2011). Dendritic T-type Ca2+ channels: Giving a boost to thalamic reticular neurons. Journal of Neuroscience, 31(15), 5551-5553. doi: 10.1523/JNEUROSCI.0067-11.2011

Gormley, A. J., Greish, K., Ray, A., Robinson, R., Gustafson, J. A., & Ghandehari, H. (2011). Gold nanorod mediated plasmonic photothermal therapy: A tool to enhance macromolecular delivery. International Journal of Pharmaceutics, 415(1-2), 315-318. doi: 10.1016/j.ijpharm.2011.05.068

Greish, K., Muller, K., IvanaJay, J., & Lee, D. H. (2011). The cooperative anticancer effect of dual styrenemaleic acid nanomiceller system against pancreatic cancer. Journal of Nanomedicine & Nanotechnology, S4, 004. doi: 10.4172/2157-7439.S4-004

Greish, K., Ray, A., Bauer, H., Larson, N., Malugin, A., Pike, D., … Ghandehari, H. (2011). Anticancer and antiangiogenic activity of HPMA copolymer-aminohexylgeldanamycin-RGDfK conjugates for prostate cancer therapy. Journal of Controlled Release, 151(3), 263-270. doi: 10.1016/j.jconrel.2010.12.015

Hellyer, S. D., Selwood, A., Rhodes, L., & Kerr, D. S. (2011). Marine algal pinnatoxins E and F cause neuromuscular block in an in vitro hemidiaphragm preparation. Toxicon, 58, 693-699. doi: 10.1016/j.toxicon.2011.09.006

Hüfner, K., Strupp, M., Smith, P., Brandt, T., & Jahn, K. (2011). Spatial separation of visual and vestibular processing in the human hippocampal formation. Annals of the New York Academy of Sciences, 1233, 177-186. doi: 10.1111/j.1749-6632.2011.06115.x

Imlach, W. L., Finch, S. C., Zhang, Y., Dunlop, J., & Dalziel, J. E. (2011). Mechanism of action of lolitrem B, a fungal endophyte derived toxin that inhibits BK large conductance Ca2+-activated K+ channels. Toxicon, 57(5), 686-694. doi: 10.1016/j.toxicon.2011.01.013

Larson, N., Greish, K., Bauer, H., Maeda, H., & Ghandehari, H. (2011). Synthesis and evaluation of poly(styrene-co-maleic acid) micellar nanocarriers for the delivery of tanespimycin. International Journal of Pharmaceutics, 420(1), 111-117. doi: 10.1016/j.ijpharm.2011.08.011

Maggo, S. D. S., Kennedy, M. A., & Clark, D. W. J. (2011). Clinical implications of pharmacogenetic variation on the effects of statins. Drug Safety, 34(1), 1-19. doi: 10.2165/11584380-000000000-00000

Nair, S. M., Rahman, R. M. A., Clarkson, A. N., Sutherland, B. A., Taurin, S., Sammut, I. A., & Appleton, I. (2011). Melatonin treatment following stroke induction modulates L-arginine metabolism. Journal of Pineal Research, 51(3), 313-323. doi: 10.1111/j.1600-079X.2011.00891.x

Ray, A., Larson, N., Pike, D. B., Grüner, M., Naik, S., Bauer, H., … Greish, K., & Ghandehari, H. (2011). Comparison of active and passive targeting of docetaxel for prostate cancer therapy by HPMA copolymer—RGDfK conjugates. Molecular Pharmaceutics, 8(4), 1090-1099. doi: 10.1021/mp100402n

Reimer, M. M., McQueen, J., Searcy, L., Scullion, G., Zonta, B., Desmazieres, A., … Gliddon, C., … Horsburgh, K. (2011). Rapid disruption of axon-clial integrity in response to mild cerebral hypoperfusion. Journal of Neuroscience, 31(49), 18185-18194. doi: 10.1523/JNEUROSCI.4936-11.2011

Rivers, J. R., Sutherland, B. A., & Ashton, J. C. (2011). Characterization of a rat hypoxia-ischemia model where duration of hypoxia is determined by seizure activity. Journal of Neuroscience Methods, 197(1), 92-96. doi: 10.1016/j.jneumeth.2011.02.002

Shelker, W., Belton, A., & Glue, P. (2011). Academic performance and career choices of older medical students at the University of Otago. New Zealand Medical Journal, 124(1346). Retrieved from http://journal.nzma.org.nz/journal/124-1346/4965/content.pdf

Somers-Edgar, T. J., Taurin, S., Larsen, L., Chandramouli, A., Nelson, M. A., & Rosengren, R. J. (2011). Mechanisms for the activity of heterocyclic cyclohexanone curcumin derivatives in estrogen receptor negative human breast cancer cell lines. Investigational New Drugs, 29(1), 87-97. doi: 10.1007/s10637-009-9339-0

Sutherland, B. A., Shaw, O. M., Clarkson, A. N., Winburn, I. C., Errington, A. C., Dixon, C. L., Lees, G., Sammut, I. A., & Appleton, I. (2011). Tin protoporphyrin provides protection following cerebral hypoxia-ischemia: Involvement of alternative pathways. Journal of Neuroscience Research, 89(8), 1284-1294. doi: 10.1002/jnr.22661

Vranyac-Tramoundanas, A., Harrison, J. C., Sawant, P. M., Kerr, D. S., & Sammut, I. A. (2011). Ischemic cardiomyopathy following seizure induction by domoic acid. American Journal of Pathology, 179(1), 141-154. doi: 10.1016/j.ajpath.2011.03.017

Yadav, B., & Greish, K. (2011). Selective inhibition of hemeoxygenase-1 as a novel therapeutic target for anticancer treatment. Journal of Nanomedicine & Nanotechnology, S4, 005. doi: 10.4172/2157-7439.S4-005

Zheng, Y., Balabhadrapatruni, S., Masumura, C., Darlington, C. L., & Smith, P. F. (2011). Effects of the putative cognitive-enhancing ampakine, CX717, on attention and object recognition memory. Current Alzheimer Research, 8(8), 876-882. doi: 10.2174/156720511798192709

Zheng, Y., Begum, S., Zhang, C., Fleming, K., Masumura, C., Zhang, M., Smith, P., & Darlington, C. (2011). Increased BrdU incorporation reflecting DNA repair, neuronal de-differentiation or possible neurogenesis in the adult cochlear nucleus following bilateral cochlear lesions in the rat. Experimental Brain Research, 210(3-4), 477-487. doi: 10.1007/s00221-010-2491-0

Zheng, Y., Hamilton, E., Begum, S., Smith, P. F., & Darlington, C. L. (2011). The effects of acoustic trauma that can cause tinnitus on spatial performance in rats. Neuroscience, 186, 48-56. doi: 10.1016/j.neuroscience.2011.04.052

Zheng, Y., Hamilton, E., McNamara, E., Smith, P. F., & Darlington, C. L. (2011). The effects of chronic tinnitus caused by acoustic trauma on social behaviour and anxiety in rats. Neuroscience, 193, 143-153. doi: 10.1016/j.neuroscience.2011.07.026

Zheng, Y., Hamilton, E., Stiles, L., McNamara, E., de Waele, C., Smith, P. F., & Darlington, C. L. (2011). Acoustic trauma that can cause tinnitus impairs impulsive control but not performance accuracy in the 5-choice serial reaction time task in rats. Neuroscience, 180, 75-84. doi: 10.1016/j.neuroscience.2011.02.040

Baek, J. H., Zheng, Y., Darlington, C. L., & Smith, P. F. (2010). Evidence that spatial memory deficits following bilateral vestibular deafferentation in rats are probably permanent. Neurobiology of Learning & Memory, 94(3), 402-413. doi: 10.1016/j.nlm.2010.08.007

Connelly, W. M., & Lees, G. (2010). Modulation and function of the autaptic connections of layer V fast spiking interneurons in the rat neocortex. Journal of Physiology, 588(12), 2047-2063. doi: 10.1113/jphysiol.2009.185199

Connelly, W. M., Schulz, J. M., Lees, G., & Reynolds, J. N. J. (2010). Differential short-term plasticity at convergent inhibitory synapses to the substantia nigra pars reticulata. Journal of Neuroscience, 30(44), 14854-14861. doi: 10.1523/JNEUROSCI.3895-10.2010

Fraser, A., Haines, S. R., Stuart, E. C., Scandlyn, M. J., Alexander, A., Somers-Edgar, T. J., & Rosengren, R. J. (2010). Deer velvet supplementation decreases the grade and metastasis of azoxymethane-induced colon cancer in the male rat. Food & Chemical Toxicology, 48, 1288-1292. doi: 10.1016/j.fct.2010.02.024

Goddard, M., Smith, P. F., & Ashton, J. C. (2010). Behavioural effects of co-administration of Δ9-tetrahydrocannabinol with fluoxetine in rats. Pharmacology, 86(2), 125-128. doi: 10.1159/000317059

Goulton, C. S., Patten, A. R., Kerr, J. R., & Kerr, D. S. (2010). Pharmacological preconditioning with GYKI 52466: A prophylactic approach to neuroprotection. Frontiers in Neuroscience, 4, 54. doi: 10.3389/fnins.2010.00054

Imlach, W. L., Finch, S. C., Miller, J. H., Meredith, A. L., & Dalziel, J. E. (2010). A role for BK channels in heart rate regulation in rodents. PLoS ONE, 5(1), e8698. doi: 10.1371/journal.pone.0008698

Liu, P., Zhang, H., Devaraj, R., Ganesalingam, G., & Smith, P. F. (2010). A multivariate analysis of the effects of aging on glutamate, GABA and arginine metabolites in the rat vestibular nucleus. Hearing Research, 269(1-2), 122-133. doi: 10.1016/j.heares.2010.06.019

Rivers, J. R., & Ashton, J. C. (2010). The development of cannabinoid CBII receptor agonists for the treatment of central neuropathies. Central Nervous System Agents in Medicinal Chemistry, 10(1), 47-64. doi: 10.2174/187152410790780145

Sawant, P. M., Mountfort, D. O., & Kerr, D. S. (2010). Spectral analysis of electrocorticographic activity during pharmacological preconditioning and seizure induction by intrahippocampal domoic acid. Hippocampus, 20(8), 994-1002. doi: 10.1002/hipo.20698

Sawant, P. M., Tyndall, J. D. A., Holland, P. T., Peake, B. M., Mountfort, D. O., & Kerr, D. S. (2010). In vivo seizure induction and affinity studies of domoic acid and isodomoic acids-D, -E and -F. Neuropharmacology, 59, 129-138. doi: 10.1016/j.neuropharm.2010.03.019

Smith, P. F. (2010). New approaches in the management of spasticity in multiple sclerosis patients: Role of cannabinoids. Therapeutics & Clinical Risk Management, 6, 59-63.

Smith, P. F., & Darlington, C. L. (2010). A possible explanation for dizziness following SSRI discontinuation. Acta Oto-Laryngologica, 130, 981-983. doi: 10.3109/00016481003602082

Stuart, E. C., Jarvis, R. M., & Rosengren, R. J. (2010). In vitro mechanism of action for the cytotoxicity elicited by the combination of epigallocatechin gallate and raloxifene in MDA-MB-231 cells. Oncology Reports, 24(3), 779-785. doi: 10.3892/or_00000921

Yadav, B., Taurin, S., Rosengren, R. J., Schumacher, M., Diederich, M., Somers-Edgar, T. J., & Larsen, L. (2010). Synthesis and cytotoxic potential of heterocyclic cyclohexanone analogues of curcumin. Bioorganic & Medicinal Chemistry, 18(18), 6701-6707. doi: 10.1016/j.bmc.2010.07.063

Zheng, Y., Mason-Parker, S. E., Logan, B., Darlington, C. L., Smith, P. F., & Abraham, W. C. (2010). Hippocampal synaptic transmission and LTP in vivo are intact following bilateral vestibular deafferentation in the rat. Hippocampus, 20(4), 461-468. doi: 10.1002/hipo.20645

Zheng, Y., Masumura, C., Chung, P., Darlington, C. L., & Smith, P. F. (2010). Cell proliferation and survival in the vestibular nucleus following bilateral vestibular deafferentation in the adult rat. Neuroscience Letters, 468(1), 85-88. doi: 10.1016/j.neulet.2009.10.070

Zheng, Y., Stiles, L., Hamilton, E., Smith, P. F., & Darlington, C. L. (2010). The effects of the synthetic cannabinoid receptor agonists, WIN55,212-2 and CP55,940, on salicylate-induced tinnitus in rats. Hearing Research, 268(1-2), 145-150. doi: 10.1016/j.heares.2010.05.015

Zheng, Y., Vagal, S., Zhu, X.-X., de Waele, C., Smith, P. F., Wang, G., Zhang, M., & Darlington, C. L. (2010). The effects of the Chinese herbal medicine EMF01 on salicylate-induced tinnitus in rats. Journal of Ethnopharmacology, 128(2), 545-548. doi: 10.1016/j.jep.2010.01.053

Alexander, A., Smith, P. F., & Rosengren, R. J. (2009). Cannabinoids in the treatment of cancer. Cancer Letters, 285(1), 6-12. doi: 10.1016/j.canlet.2009.04.005

Baek, J. h., Zheng, Y., Darlington, C. L., & Smith, P. F. (2009). The CB1 receptor agonist, WIN 55,212-2, dose-dependently disrupts object recognition memory in adult rats. Neuroscience Letters, 464(1), 71-73. doi: 10.1016/j.neulet.2009.08.008

Chindo, B. A., Anuka, J. A., McNeil, L., Yaro, A. H., Adamu, S. S., Amos, S., Connelly, W. K., Lees, G., & Gamaniel, K. S. (2009). Anticonvulsant properties of saponins from Ficus platyphylla stem bark. Brain Research Bulletin, 78(6), 276-282. doi: 10.1016/j.brainresbull.2008.12.005

Connelly, W. M., & Baggott, M. J. (2009). Role of endocannabinoids in 5-HT2 receptor-mediated effects. Journal of Neurophysiology, 101(1), 5-7. doi: 10.1152/jn.91054.2008

Connelly, W. M., Shenton, F. C., Lethbridge, N., Leurs, R., Waldvogel, H. J., Faull, R. L. M., Lees, G., & Chazot, P. L. (2009). The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS. British Journal of Pharmacology, 157(1), 55-63. doi: 10.1111/j.1476-5381.2009.00227.x

Darlington, C. L., Goddard, M., Zheng, Y., & Smith, P. F. (2009). Anxiety-related behavior and biogenic amine pathways in the rat following bilateral vestibular lesions. Annals of the New York Academy of Sciences, 1164(1), 134-139. doi: 10.1111/j.1749-6632.2008.03725.x

Gliddon, C. M., Shao, Z., LeMaistre, J. L., & Anderson, C. M. (2009). Cellular distribution of the neutral amino acid transporter subtype ASCT2 in mouse brain. Journal of Neurochemistry, 108, 372-383. doi: 10.1111/j.1471-4159.2008.05767.x

Graham, E. S., Ashton, J. C., & Glass, M. (2009). Cannabinoid receptors: A brief history and 'What's hot'. Frontiers in Bioscience, 14, 944-957. doi: 10.2741/3288

Imlach, W. L., Finch, S. C., Dunlop, J., & Dalziel, J. E. (2009). Structural determinants of lolitrems for inhibition of BK large conductance Ca2+-activated K+ channels. European Journal of Pharmacology, 605(1-3), 36-45. doi: 10.1016/j.ejphar.2008.12.031

Lees, G., & Shipton, E. (2009). Voltage-gated sodium channels in nociception and their potential as targets for new drugs in treatment of chronic neuropathic pain. Current Anaesthesia & Critical Care, 20(5-6), 204-208. doi: 10.1016/j.cacc.2009.06.002

Sandbo, N., Kregel, S., Taurin, S., Bhorade, S., & Dulin, N. O. (2009). Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-β. American Journal of Respiratory Cell & Molecular Biology, 41(3), 332-338. doi: 10.1165/rcmb.2008-0288OC

Smith, P. F., Brandt, T., Strupp, M., Darlington, C. L., & Zheng, Y. (2009). Balance before reason in rats and humans. Annals of the New York Academy of Sciences, 1164(1), 127-133. doi: 10.1111/j.1749-6632.2008.03726.x

Somers-Edgar, T. J., & Rosengren, R. J. (2009). Coenzyme Q0 induces apoptosis and modulates the cell cycle in estrogen receptor negative breast cancer cells. Anti-Cancer Drugs, 20(1), 33-40. doi: 10.1097/CAD.0b013e328314b5c5

Sun, Q., Taurin, S., Sethakorn, N., Long, X., Imamura, M., Wang, D.-Z., … Miano, J. M. (2009). Myocardin-dependent activation of the CArG box-rich smooth muscle γ-actin gene: Preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein. Journal of Biological Chemistry, 284(47), 32582-32590. doi: 10.1074/jbc.M109.033910

Sutherland, B. A., Rahman, R. M. A., Clarkson, A. N., Shaw, O. M., Nair, S. M., & Appleton, I. (2009). Cerebral heme oxygenase 1 and 2 spatial distribution is modulated following injury from hypoxia-ischemia and middle cerebral artery occlusion in rats. Neuroscience Research, 65(4), 326-334. doi: 10.1016/j.neures.2009.08.007

Taurin, S., Sandbo, N., Yau, D. M., Sethakorn, N., Kach, J., & Dulin, N. O. (2009). Phosphorylation of myocardin by extracellular signal-regulated kinase. Journal of Biological Chemistry, 284(49), 33789-33794. doi: 10.1074/jbc.M109.048983

van Rensburg, R., Errington, D. R., Ennaceur, A., Lees, G., Obrenovitch, T. P., & Chazot, P. L. (2009). A new model for the study of high-K+-induced preconditioning in cultured neurones: Role of N-methyl-D-aspartate and α7-nicotinic acetylcholine receptors. Journal of Neuroscience Methods, 177(2), 311-316. doi: 10.1016/j.jneumeth.2008.10.012

Zheng, Y., Balabhadrapatruni, S., Masumura, C., Munro, O., Darlington, C. L., & Smith, P. F. (2009). Bilateral vestibular deafferentation causes deficits in a 5-choice serial reaction time task in rats. Behavioural Brain Research, 203, 113-117. doi: 10.1016/j.bbr.2009.04.027

Zheng, Y., Goddard, M., Darlington, C. L., & Smith, P. F. (2009). Long-term deficits on a foraging task after bilateral vestibular deafferentation in rats. Hippocampus, 19(5), 480-486. doi: 10.1002/hipo.20533

Abuhamdah, S., Huang, L., Elliott, M. S. J., Howes, M.-J. R., Ballard, C., Holmes, C., … Lees, G., & Chazot, P. L. (2008). Pharmacological profile of an essential oil derived from Melissa officinalis with anti-agitation properties: Focus on ligand-gated channels. Journal of Pharmacy & Pharmacology, 60(3), 377-384.

Akimova, O. A., Taurin, S., Dulin, N. O., & Orlov, S. N. (2008). Purinergic inhibition of Na+,K+,Cl- cotransport in C11-MDCK cells: Role of stress-activated protein kinases. Purinergic Signalling, 4(2), 183-191. doi: 10.1007/s11302-007-9057-z

Ashton, J. C., & Milligan, E. D. (2008). Cannabinoids for the treatment of neuropathic pain: Clinical evidence. Current Opinion in Investigational Drugs, 9(1), 65-75.

Ashton, J. C., Smith, P. F., & Darlington, C. L. (2008). The effect of Δ9-tetrahydrocannabinol on the extinction of an adverse associative memory. Pharmacology, 81(1), 18-20. doi: 10.1159/000107663

Ashton, J. C., Wright, J. L., McPartland, J. M., & Tyndall, J. D. A. (2008). Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists. Current Medicinal Chemistry, 15, 1428-1443.

Baek, J.-H., Zheng, Y., Darlington, C. L., & Smith, P. F. (2008). Cannabinoid CB2 receptor expression in the rat brainstem cochlear and vestibular nuclei. Acta Oto-Laryngologica, 128(9), 961-967. doi: 10.1080/00016480701796944

Clark, D. W. J., Ashton, J. A., Zhou, L., Wallace, A. K., & Kennedy, M. A. (2008). Pharmacogenetic investigation using a pharmacovigilance database. PharmacoVigilance Review, 2(3), 9-13.

Clark, D. W. J., Coulter, D. M., & Besag, F. M. C. (2008). Randomized controlled trials and assessment of drug safety. Drug Safety, 31(12), 1057-1061. doi: 10.2165/0002018-200831120-00002

Errington, A. C., Stöhr, T., Heers, C., & Lees, G. (2008). The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels. Molecular Pharmacology, 73(1), 157-169.

Goddard, M., Zheng, Y., Darlington, C. L., & Smith, P. F. (2008). Locomotor and exploratory behavior in the rat following bilateral vestibular deafferentation. Behavioral Neuroscience, 122(2), 448-459. doi: 10.1037/0735-7044.122.2.448

Goddard, M., Zheng, Y., Darlington, C. L., & Smith, P. F. (2008). Monoamine transporter and enzyme expression in the medial temporal lobe and frontal cortex following chronic bilateral vestibular loss. Neuroscience Letters, 437(2), 107-110. doi: 10.1016/j.neulet.2008.03.073

Goddard, M., Zheng, Y., Darlington, C. L., & Smith, P. F. (2008). Synaptic protein expression in the medial temporal lobe and frontal cortex following chronic bilateral vestibular loss. Hippocampus, 18(5), 440-444. doi: 10.1002/hipo.20416

Howard, R., Karageorge, G., van Harselaar, K., Bell, M., Basford, P., Schultz, M., & Derrett, S. (2008). Post-procedure surveillance in liver biopsy: How long is long enough? New Zealand Medical Journal, 121(1280). Retrieved from http://journal.nzma.org.nz/journal/121-1280/3219/content.pdf

Huang, L., Abuhamdah, S., Howes, M.-J. R., Dixon, C. L., Ballard, C., Elliott, M. S. J., … Lees, G., & Chazot, P. L. (2008). Pharmacological profile of essential oils derived from Lavandula angustifolia and Melissa officinalis with anti-agitation properties: Focus on ligand-gated channels. Journal of Pharmacy & Pharmacology, 60(11), 1515-1522.

Liu, P., Chary, S., Devaraj, R., Jing, Y., Darlington, C. L., Smith, P. F., Tucker, I. G., & Zhang, H. (2008). Effects of aging on agmatine levels in memory-associated brain structures. Hippocampus, 18, 853-856. doi: 10.1002/hipo.20448

Liu, P., Smith, P. F., & Darlington, C. L. (2008). Glutamate receptor subunits expression in memory-associated brain structures: Regional variations and effects of aging. Synapse, 62, 834-841. doi: 10.1002/syn.20563

Numata, M., Fawcett, J. P., & Rosengren, R. J. (2008). Induction of in vitro EROD activity and in vivo caffeine metabolism in two species of New Zealand birds. Environmental Toxicology & Pharmacology, 25, 358-364. doi: 10.1016/j.etap.2007.11.005

Numata, M., Fawcett, J. P., Saville, D. J., & Rosengren, R. J. (2008). Hepatic cytochrome P450 activity and pollutant concentrations in paradise shelducks and southern black-backed gulls in the South Island of New Zealand. Ecotoxicology, 17, 697-708. doi: 10.1007/s10646-008-0218-9

Pugazhenthi, K., Kapoor, M., Clarkson, A. N., Hall, I., & Appleton, I. (2008). Melatonin accelerates the process of wound repair in full-thickness incisional wounds. Journal of Pineal Research, 44(4), 387-396. doi: 10.1111/j.1600-079X.2007.00541.x

Sawant, P. M., Holland, P. T., Mountfort, D. O., & Kerr, D. S. (2008). In vivo seizure induction and pharmacological preconditioning by domoic acid and isodomoic acids A, B and C. Neuropharmacology, 55, 1412-1418. doi: 10.1016/j.neuropharm.2008.09.001

Scandlyn, M. J., Stuart, E. C., & Rosengren, R. J. (2008). Sex-specific differences in CYP450 isoforms in humans. Expert Opinion on Drug Metabolism & Toxicology, 4(4), 413-424. doi: 10.1517/17425255.4.4.413

Scandlyn, M. J., Stuart, E. C., Somers-Edgar, T. J., Menzies, A. R., & Rosengren, R. J. (2008). A new role for tamoxifen in oestrogen receptor-negative breast cancer when it is combined with epigallocatechin gallate. British Journal of Cancer, 99(7), 1056-1063. doi: 10.1038/sj.bjc.6604634

Smith, P. F. (2008). Inflammation in Parkinson's disease: An update. Current Opinion in Investigational Drugs, 9(5), 478-484.

Somers-Edgar, T. J., Scandlyn, M. J., Stuart, E. C., Le Nedelec, M. J., Valentine, S. P., & Rosengren, R. J. (2008). The combination of epigallocatechin gallate and curcumin suppresses ERα-breast cancer cell growth in vitro and in vivo. International Journal of Cancer, 122(9), 1966-1971.

Stuart, E. C., & Rosengren, R. J. (2008). The combination of raloxifene and epigallocatechin gallate suppresses growth and induces apoptosis in MDA-MB-231 cells. Life Sciences, 82(17-18), 943-948. doi: 10.1016/j.lfs.2008.02.009

Taurin, S., Sandbo, N., Yau, D. M., Sethakorn, N., & Dulin, N. O. (2008). Phosphorylation of β-catenin by PKA promotes ATP-induced proliferation of vascular smooth muscle cells. American Journal of Physiology: Cell Physiology, 294, C1169-C1174. doi: 10.1152/ajpcell.00096.2008

Vranyac-Tramoundanas, A., Harrison, J. C., Clarkson, A. N., Kapoor, M., Winburn, I. C., Kerr, D. S., & Sammut, I. A. (2008). Domoic acid impairment of cardiac energetics. Toxicological Sciences, 105(2), 395-407. doi: 10.1093/toxsci/kfn132

Yau, D. M., Sethakorn, N., Taurin, S., Kregel, S., Sandbo, N., Camoretti-Mercado, B., … Dulin, N. O. (2008). Regulation of Smad-mediated gene transcription by RGS3. Molecular Pharmacology, 73(5), 1356-1361. doi: 10.1124/mol.108.044990

Zheng, Y., Goddard, M., Darlington, C. L., & Smith, P. F. (2008). Effects of bilateral vestibular deafferentation on anxiety-related behaviours in Wistar rats. Behavioural Brain Research, 193(1), 55-62. doi: 10.1016/j.bbr.2008.04.018

Zheng, Y., Hooton, K., Smith, P. F., & Darlington, C. L. (2008). Carbamazepine reduces the behavioural manifestations of tinnitus following salicylate treatments in rats. Acta Oto-Laryngologica, 128(1), 48-52. doi: 10.1080/00016480701361939

Ashton, J. C. (2007). Cannabinoids for the treatment of inflammation. Current Opinion in Investigational Drugs, 8(5), 373-384.

Ashton, J. C., & Glass, M. (2007). The cannabinoid CB2 receptor as a target for inflammation-dependent neurodegeneration. Current Neuropharmacology, 5(2), 73-80.

Ashton, J. C., & Smith, P. F. (2007). Cannabinoids and cardiovascular disease: The outlook for clinical treatments. Current Vascular Pharmacology, 5(3), 175-184.

Ashton, J. C., Rahman, R. M. A., Nair, S. M., Sutherland, B. A., Glass, M., & Appleton, I. (2007). Cerebral hypoxia-ischemia and middle cerebral artery occlusion induce expression of the cannabinoid CB2 receptor in the brain. Neuroscience Letters, 412, 114-117.

Clarkson, A. N., Clarkson, J., Jackson, D. M., & Sammut, I. A. (2007). Mitochondrial involvement in transhemispheric diaschisis following hypoxia-ischemia: Clomethiazole-mediated amelioration. Neuroscience, 144, 547-561.

Clarkson, A. N., Liu, H., Schiborra, F., Shaw, O., Sammut, I. A., Jackson, D. M., & Appleton, I. (2007). Angiogenesis as a predictive marker of neurological outcome following hypoxia-ischemia. Brain Research, 1171, 111-121.

Darlington, C. (2007). MBP-8298, a synthetic peptide analog of myelin basic protein for the treatment of multiple sclerosis. Current Opinion in Molecular Therapeutics, 9, 398-402.

Darlington, C. L. (2007). The changing face of insulin receptors. Current Opinion in Investigational Drugs, 8(11), 885-886.

Darlington, C. L., & Smith, P. F. (2007). Drug treatments for tinnitus. Progress in Brain Research, 166, 249-262. doi: 10.1016/s0079-6123(07)66023-3

Foronda, N. M., Fowles, J., Smith, N., Taylor, M., Temple, W., & Darlington, C. (2007). The use of myocardial and testicular end points as a basis for estimating a proposed tolerable daily intake for sodium monofluoroacetete (1080). Regulatory Toxicology & Pharmacology, 47(1), 29-36.

Hesp, B. R., Clarkson, A. N., Sawant, P. M., & Kerr, D. S. (2007). Domoic acid preconditioning and seizure induction in young and aged rats. Epilepsy Research, 76, 103-112.

Payne, H. L., Connelly, W. M., Ives, J. H., Lehner, R., Furtmuller, B., Sieghart, W., … Lees, G., & Thompson, C. L. (2007). GABAA α6-containing receptors are selectively compromised in cerebellar granule cells of the ataxic mouse, stargazer. Journal of Biological Chemistry, 282(40), 29130-29143.

Sawant, P. M., Weare, B. A., Holland, P. T., Selwood, A. I., King, K. L., Mikulski, C. M., … Kerr, D. S. (2007). Isodomoic acids A and C exhibit low KA receptor affinity and reduced in vitro potency relative to domoic acid in region CA1 of rat hippocampus. Toxicon, 50, 627-638.

Smith, P. F. (2007). Symptomatic treatment of multiple sclerosis using cannabinoids: Recent advances. Expert Review of Neurotherapeutics, 7(9), 1157-1163.

Smith, P. F. (2007). Will medicinal cannabinoids prove to be useful clinically? Current Drug Therapy, 2(2), 143-150.

Stuart, E. C., Larsen, L., & Rosengren, R. J. (2007). Potential mechanisms for the synergistic cytotoxicity elicited by 4-hydroxytamoxifen and epigallocatechin gallate in MDA-MB-231 cells. International Journal of Oncology, 30(6), 1407-1412.

Zheng, Y., Baek, J.-H., Smith, P. F., & Darlington, C. L. (2007). Cannabinoid receptor down-regulation in the ventral cochlear nucleus in a salicylate model of tinnitus. Hearing Research, 228, 105-111.

Zheng, Y., Goddard, M., Darlington, C. L., & Smith, P. F. (2007). Bilateral vestibular deafferentation impairs performance in a spatial forced alternation task in rats. Hippocampus, 17, 253-256.

Ashton, J. C., Darlington, C. L., & Smith, P. F. (2006). Co-distribution of the cannabinoid CB1 receptor and the 5-HT transporter in the rat amygdale. European Journal of Pharmacology, 537, 70-71.

Ashton, J. C., Friberg, D., Darlington, C. L., & Smith, P. F. (2006). Expression of the cannabinoid CB2 receptor in the rat cerebellum: An immunohistochemical study. Neuroscience Letters, 396, 113-116.

Brewer, L. D., Porter, N. M., Kerr, D. S., Landfield, P. W., & Thibault, O. (2006). Chronic 1 alpha,25-(OH)(2) vitamin D-3 treatment reduces Ca2+-mediated hippocampal biomarkers of aging. Cell Calcium, 40(3), 277-286.

Clark, D. W. J., & Harrison-Woolrych, M. (2006). The role of the New Zealand Intensive Medicines Monitoring Programme in identification of previously unrecognised signals of adverse drug reactions. Current Drug Safety, 1, 169-178. doi: 10.2174/157488606776930544

Clark, D. W. J., & Strandell, J. (2006). Myopathy including polymyositis: A likely class adverse effect of proton pump inhibitors. European Journal of Clinical Pharmacology, 62(6), 473-479.

Errington, A. C., Coyne, L., Stöhr, T., Selve, N., & Lees, G. (2006). Seeking a mechanism of action for the novel anticonvulsant lacosamide. Neuropharmacology, 50(8), 1016-1029.

Fergusson, D. M., Poulton, R., Smith, P. F., & Boden, J. M. (2006). Cannabis and psychosis. BMJ, 332, 172-175. doi: 10.1136/bmj.332.7534.172

Galloway, D. J., & Ledingham, J. (2006). Additional lichen records from New Zealand 43. Umbilicaria deusta (L.) Baumg. Australasian Lichenology, 58, 14-16.

Goodin, M. G., Bray, B. J., & Rosengren, R. J. (2006). Sex- and strain-dependent effects of epigallocatechin gallate (EGCG) and epicatechin gallate (ECG) in the mouse. Food & Chemical Toxicology, 44, 1496-1504.

Harrison-Woolrych, M., Clark, D. W. J., Hill, G. R., Rees, M. I., & Skinner, J. R. (2006). QT interval prolongation associated with sibutramine treatment. British Journal of Clinical Pharmacology, 61(4), 464-469.

Harrison-Woolrych, M., Hill, G. R., & Clark, D. W. J. (2006). Bruising associated with sibutramine: Results from postmarketing surveillance in New Zealand. International Journal of Obesity, 30, 1315-1317. doi: 10.1038/sj.ijo.0803268

Kapoor, M., Kojima, F., Appleton, I., Kawai, S., & Crofford, L. J. (2006). Major enzymatic pathways in dermal wound healing: Current understanding and future therapeutic targets. Current Opinion in Investigational Drugs, 7(5), 418-422.

Landar, A., Giles, N., Zmijewski, J. W., Watanabe, N., Oh, J.-Y., & Darley-Usmar, V. M. (2006). Modification of lipids by reactive oxygen and nitrogen species: The oxy-nitroxy-lipidome and its role in redox cell signaling. Future Lipidology, 1(2), 203-211. doi: 10.2217/17460875.1.2.203

Lees, G., Stöhr, T., & Errington, A. C. (2006). Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro. Neuropharmacology, 50, 98-110.

Payne, H. L., Donoghue, P. S., Connelly, W. M. K., Hinterreiter, S., Tiwari, P., Ives, J. H., … Lees, G., & Thompson, C. L. (2006). Aberrant GABA(A) receptor expression in the dentate gyrus of the epileptic mutant mouse stargazer. Journal of Neuroscience, 26(33), 8600-8608.

Priest, V. L., Begg, E. J., Gardiner, S. J., Frampton, C. M., Gearry, R. B., Barclay, M. L., Clark, D. W., & Hansen, P. (2006). Pharmacoeconomic analyses of azathioprine, methotrexate and prospective pharmacogenetic testing for the management of inflammatory bowel disease. Pharmacoeconomics, 24(8), 767-781.

Russell, N. A., Horii, A., Smith, P. F., Darlington, C. L., & Bilkey, D. K. (2006). Lesions of the vestibular system disrupt hippocampal theta rhythm in the rat. Journal of Neurophysiology, 96, 4-14.

Smith, P. F., Ashton, J. C., & Darlington, C. L. (2006). The endocannabinoid system: A new player in the neurochemical control of vestibular function? Audiology & Neurotology, 11, 207-212.

Stuart, E. C., Scandlyn, M. J., & Rosengren, R. J. (2006). Role of epigallocatechin gallate (EGCG) in the treatment of breast and prostate cancer. Life Sciences, 79, 2329-2336.

Sutherland, B. A., Rahman, R. M. A., & Appleton, I. (2006). Mechanisms of action of green tea catechins, with a focus on ischemia-induced neurodegeneration. Journal of Nutritional Biochemistry, 17(5), 291-306.

Valentine, S. P., Le Nedelec, M. J., Menzies, A. R., Scandlyn, M. J., Goodin, M. G., & Rosengren, R. J. (2006). Curcumin modulates drug metabolizing enzymes in the female Swiss Webster mouse. Life Sciences, 78, 2391-2398.

Zheng, Y., Darlington, C. L., & Smith, P. F. (2006). Impairment and recovery on a food foraging task following unilateral vestibular deafferentation in rats. Hippocampus, 16, 368-378.

Zheng, Y., Lee, H. S., Smith, P. F., & Darlington, C. L. (2006). Neuronal nitric oxide synthase expression in the cochlear nucleus in a salicylate model of tinnitus. Brain Research, 1123, 201-206.

Abuhamdah, S., Furstner, A., Lees, G., & Chazot, P. L. (2005). Radioligand binding studies of caloporoside and novel congeners with contrasting effects upon [S-35] TBPS binding to the mammalian GABA (A) receptor. Biochemical Pharmacology, 70(9), 1382-1388.

Adlam, V. J., Harrison, J. C., Porteous, C. M., James, A. M., Smith, R. A. J., Murphy, M. P., & Sammut, I. A. (2005). Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury. FASEB Journal, 19, 1088-1095.

Ashton, J. C., Khalessi, A., Kapoor, M., Clarkson, A., Sammut, I. A., Darlington, C. L., & Smith, P. F. (2005). Characterization of mitochondrial respiratory chain energetics in the vestibular nucleus complex [Short Communication]. Acta Oto-Laryngologica, 125, 422-425.

Ashton, J. C., Little, E., Muir, M., Smith, P. F., & Darlington, C. L. (2005). Mitochondrial ultrastructure and apoptotic protein expression in the vestibular nucleus complex following unilateral labyrinthectomy. Brain Research, 1055, 165-170.

Benians, A., Nobles, M., Hosny, S., & Tinker, A. (2005). Regulators of G-protein signaling form a quaternary complex with the agonist receptor, and G-protein. Journal of Biological Chemistry, 280(14), 13383-13394.

Brandt, T., Schautzer, F., Hamilton, D. A., Brüning, R., Markowitsch, H. J., Kalla, R., Darlington, C., Smith, P., & Strupp, M. (2005). Vestibular loss causes hippocampal atrophy and impaired spatial memory in humans. Brain, 128(11), 2732-2741. doi: 10.1093/brain/awh617

Clarkson, A. N., Liu, H., Rahman, R., Jackson, D. M., Appleton, I., & Kerr, D. S. (2005). Clomethiazole: Mechanisms underlying lasting neuroprotection after hypoxia-ischemia. FASEB Journal, 19(8), 1036-1038.

Clarkson, A. N., Sutherland, B. A., & Appleton, I. (2005). The biology and pathology of hypoxia-ischemia: An update. Archivum Immunologiae et Therapiae Experimentalis, 53, 213-225.

Darlington, C. L. (2005). Astrocytes as targets for neuroprotective drugs. Current Opinion in Investigational Drugs, 6(7), 700-703.

Darlington, C. L. (2005). Technology evaluation: NeuroVax, Immune Response Corp. Current Opinion in Molecular Therapeutics, 7(6), 598-603.

Darlington, C. L. (2005). The potential role for statins in the treatment of multiple sclerosis. Current Opinion in Investigational Drugs, 6(7), 667-671.

Dougalis, A., & Lees, G. (2005). The endocannabinoid signalling system: Implications for anaesthesia and the pain clinic. Current Anaesthesia & Critical Care, 16, 71-80.

Errington, A. C., Madison, K., Kumar, A., & Lees, G. (2005). Voltage-gated sodium channels and their roles in drug action. Current Anaesthesia & Critical Care, 16, 81-87.

Errington, A. C., Stöhr, T., & Lees, G. (2005). Voltage gated ion channels: Targets for anticonvulsant drugs. Current Topics in Medicinal Chemistry, 5, 15-30.

Gliddon, C. M., Darlington, C. L., & Smith, P. F. (2005). Effects of chronic infusion of a GABAA receptor agonist or antagonist into the vestibular nuclear complex on vestibular compensation in the guinea pig. Journal of Pharmacology & Experimental Therapeutics, 313(3), 1126-1135. doi: 10.1124/jpet.104.082172

Gliddon, C. M., Darlington, C. L., & Smith, P. F. (2005). GABAA receptor subunit expression in the guinea pig vestibular nucleus complex during the development of vestibular compensation. Experimental Brain Research, 166, 71-77. doi: 10.1007/s00221-005-2344-4

Gliddon, C. M., Darlington, C. L., & Smith, P. F. (2005). GABAergic systems in the vestibular nucleus and their contribution to vestibular compensation. Progress in Neurobiology, 75, 53-81. doi: 10.1016/j.pneurobio.2004.11.001

Hesp, B. R., Harrison, J. C., Selwood, A. I., Holland, P. T., & Kerr, D. S. (2005). Detection of domoic acid in rat serum and brain by direct competitive enzyme-linked immunosorbent assay (cELISA). Analytical & Bioanalytical Chemistry, 383(5), 783-786.

Hoedemaker, J. R., Peake, B. M., & Kerr, D. S. (2005). Reduction in functional potency of the neurotoxin domoic acid in the presence of cadmium and zinc ions. Environmental Toxicology & Pharmacology, 20, 175-181.

Ledingham, J. M., & Ashton, N. (2005). Remodelling of mesenteric arteries in genetically hypertensive rats cross-fostered from birth to normotensive Wistar rats. Clinical & Experimental Pharmacology & Physiology, 32(10), 859-864.

Ledingham, J. M., & Laverty, R. (2005). Effect of simvastatin given alone in combination with valsartan or enalapril on blood pressure and the structure of mesenteric resistance arteries and the basilar artery in the genetically hypertensive rat model. Clinical & Experimental Pharmacology & Physiology, 32, 76-85.

Ledingham, J. M., & Laverty, R. (2005). Effects of glitazones on blood pressure and vascular structure in mesenteric resistance arteries and basilar artery from genetically hypertensive rats. Clinical & Experimental Pharmacology & Physiology, 32, 919-925.

Lindsay, L., Liu, P., Gliddon, C., Zheng, Y., Smith, P. F., & Darlington, C. L. (2005). Cytosolic glucocorticoid receptor expression in the rat vestibular nucleus and hippocampus following unilateral vestibular deafferentation. Experimental Brain Research, 162, 309-314. doi: 10.1007/s00221-004-2168-7

Liu, P., Smith, P. F., Appleton, I., Darlington, C. L., & Bilkey, D. K. (2005). Hippocampal nitric oxide synthase and arginase and age-associated behavioral deficits. Hippocampus, 15, 642-655.

Nobles, M., Benians, A., & Tinker, A. (2005). Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells. PNAS, 102(51), 18706-18711.

Parry, D. J., Winburn, I. C., Wilkins, G. T., & Bunton, R. W. (2005). Expanding retrograde saphenous vein graft aneurysm treated with endovascular coiling. Annals of Thoracic Surgery, 80, 2374-2376.

Rahman, R. M. A., Nair, S. M., Helps, S. C., Shaw, O. M., Sims, N. R., Rosengren, R. J., & Appleton, I. (2005). ( - )-Epigallocatechin gallate as an intervention for the acute treatment of cerebral ischemia. Neuroscience Letters, 382(3), 227-230. doi: 10.1016/j.neulet.2005.03.018

Smith, P. F. (2005). Cannabinoids as potential anti-epileptic drugs. Current Opinion in Investigational Drugs, 6(7), 680-685.

Smith, P. F. (2005). The safety of cannabinoids for the treatment of multiple sclerosis. Expert Opinion on Drug Safety, 4(3), 443-456.

Smith, P. F., & Darlington, C. L. (2005). Drug treatments for subjective tinnitus: Serendipitous discovery versus rational drug design. Current Opinion in Investigational Drugs, 6(7), 712-716.

Smith, P. F., Horii, A., Russell, N., Bilkey, D. K., Zheng, Y., Liu, P., Kerr, D. S., & Darlington, C. L. (2005). The effects of vestibular lesions on hippocampal function in rats. Progress in Neurobiology, 75, 391-405.

Smith, P. F., Zheng, Y., & Darlington, C. L. (2005). Ginkgo biloba extracts for tinnitus: More hype than hope? Journal of Ethnopharmacology, 100, 95-99.

Smith, P. F., Zheng, Y., Horii, A., & Darlington, C. L. (2005). Does vestibular damage cause cognitive dysfunction in humans? [Review]. Journal of Vestibular Research, 15, 1-9.

Sutherland, B. A., Shaw, O. M., Clarkson, A. N., Jackson, D. M., Sammut, I. A., & Appleton, I. (2005). Neuroprotective effects of (-)-epigallocatechin gallate following hypoxia-ischemia-induced brain damage: Novel mechanisms of action. FASEB Journal, 19(2), 258-260. doi: 10.1096/fj.04-2806fje

Zhang, R., Ashton, J., Horii, A., Darlington, C. L., & Smith, P. F. (2005). Immunocytochemical and stereological analysis of GABAB receptor subunit expression in the rat vestibular nucleus following unilateral vestibular deafferentation. Brain Research, 1037(1-2), 107-113. doi: 10.1016/j.brainres.2005.01.018

Zhang, R., Smith, P. F., & Darlington, C. L. (2005). Immunocytochemical and stereological studies of the rat vestibular nucleus: Optimal research methods using glucocorticoid receptors as an example. Journal of Neuroscience Methods, 144, 99-106.

Zhang, R., Smith, P. F., & Darlington, C. L. (2005). Immunocytochemical and stereological study of glucocorticoid receptors in rat medial vestibular nucleus neurons and the effects of unilateral vestibular deafferentation. Acta Oto-Laryngologica, 125, 1258-1264.

Ashton, J. C., Appleton, I., Darlington, C. L., & Smith, P. F. (2004). Cannabinoid CB1 receptor protein expression in the rat choroid plexus: A possible involvement of cannabinoids in the regulation of cerebrospinal fluid. Neuroscience Letters, 364, 40-42.

Ashton, J. C., Appleton, I., Darlington, C. L., & Smith, P. F. (2004). Immunohistochemical localization of cannabinoid CB1 receptor in inhibitory interneurons in the cerebellum. Cerebellum, 3, 222-226.

Ashton, J. C., Appleton, I., Darlington, C. L., & Smith, P. F. (2004). Immunohistochemical localization of cerebrovascular cannabinoid CB1 receptor protein. Journal of Cardiovascular Pharmacology, 44(5), 517-519.

Ashton, J. C., Zheng, Y., Liu, P., Darlington, C. L., & Smith, P. F. (2004). Immunohistochemical characterisation and localisation of cannabinoid CB1 receptor protein in the rat vestibular nucleus complex and the effects of unilateral vestibular deafferentation. Brain Research, 1021, 264-271.

Chisholm, K., Bray, B. J., & Rosengren, R. J. (2004). Tamoxifen and epigallocatechin gallate are synergistically cytotoxic to MDA-MB-231 human breast cancer cells. Anti-Cancer Drugs, 15, 889-897.

Clark, D. W. J., & Harrison-Woolrych, M. (2004). Sibutramine may be associated with memory impairment. British Medical Journal, 329, 1316.

Clark, D. W. J., Donnelly, E., Coulter, D. M., Roberts, R. L., & Kennedy, M. A. (2004). Linking pharmacovigilance with pharmacogenetics. Drug Safety, 27(15), 1171-1184.

Clark, D. W. J., Layton, D., & Shakir, S. A. W. (2004). Do some inhibitors of COX-2 increase the risk of thromboembolic events? Drug Safety, 27(7), 427-456.

Clarkson, A. N., Liu, H., Pearson, L., Kapoor, M., Harrison, J. C., Sammut, I. A., Jackson, D. M., & Appleton, I. (2004). Neuroprotective effects of spermine following hypoxia-ischemia-induced brain damage: A mechanistic study. FASEB Journal, 18(10), 1114-1116.

Clarkson, A. N., Rahman, R. M. A., & Appleton, I. (2004). Inflammation and autoimmunity as a central theme in neurodegenerative disorders: Fact or fiction? Current Opinion in Investigational Drugs, 5(7), 706-713.

Coulter, D. M., & Clark, D. W. J. (2004). Disturbance of vision by COX-2 inhibitors. Expert Opinion on Drug Safety, 3(6), 607-614.

Dougalis, A., Lees, G., & Ganellin, C. R. (2004). The sleep inducing brain lipid cis-oleamide (cOA) does not modulate serotonergic transmission in the CA1 pyramidal neurons of the hippocampus in vitro. Neuropharmacology, 46, 63-73.

Dougalis, A., Lees, G., & Ganellin, C. R. (2004). The sleep lipid oleamide may represent an endogenous anticonvulsant: An in vitro comparative study in the 4-aminopyridine rat brain-slice model. Neuropharmacology, 46, 541-554.

Gliddon, C. M., Darlington, C. L., & Smith, P. F. (2004). Rapid vestibular compensation in guinea pig even with prolonged anesthesia. Neuroscience Letters, 371, 138-141.

Harrison-Woolrych, M., & Clark, D. W. J. (2004). Nose bleeds associated with use of risperidone. British Medical Journal, 328, 1416.

Hesp, B. R., Wrightson, T., Mullaney, I., & Kerr, D. S. (2004). Kainate receptor agonists and antagonists mediate tolerance to kainic acid and reduce high-affinity GTPase activity in young, but not aged, rat hippocampus. Journal of Neurochemistry, 90, 70-79.

Horii, A., Masumura, C., Smith, P. F., Darlington, C. L., Kitahara, T., Uno, A., … Kubo, T. (2004). Microarray analysis of gene expression in the rat vestibular nucleus complex following unilateral vestibular deafferentation. Journal of Neurochemistry, 91, 975-982.

Horii, A., Russell, N. A., Smith, P. F., Darlington, C. L., & Bilkey, D. K. (2004). Vestibular influences on CA1 neurons in the rat hippocampus: An electrophysiological study in vivo. Experimental Brain Research, 155(2), 245-250.

Jackson, D. M., & Sammut, I. A. (2004). Oxygen free radical traps for the treatment of ischemia-associated organ injury. Current Opinion in Investigational Drugs, 5(1), 50-54.

Kapoor, M., Howard, R., Hall, I., & Appleton, I. (2004). Effects of epicatechin gallate on wound healing and scar formation in a full thickness incisional wound healing model in rats. American Journal of Pathology, 165(1), 299-307.

Lees, G., & Coyne, L. (2004). The orexins: A novel family of sleep regulating neuropeptides. Current Anaesthesia & Critical Care, 15, 75-77.

Lees, G., & Dougalis, A. (2004). Differential effects of the sleep-inducing lipid olemide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro. Brain Research, 997, 1-14.

Lees, G., Coyne, L., Zheng, J., & Nicholson, R. A. (2004). Mechanisms for resin acid effects on membrane currents and GABAA receptors in mammalian CNS. Environmental Toxicology & Pharmacology, 15, 61-69.

Liu, P., Gliddon, C. M., Lindsay, L., Darlington, C. L., & Smith, P. F. (2004). Nitric oxide synthase and arginase expression changes in the rat perirhinal and entorhinal cortices following unilateral vestibular damage: A link to deficits in object recognition? Journal of Vestibular Research, 14, 411-417.

Liu, P., Jarrard, L. E., & Bilkey, D. K. (2004). Excitotoxic lesions of the pre- and parasubiculum disrupt the place fields of hippocampal pyramidal cells. Hippocampus, 14(1), 107-116.

Liu, P., Smith, P. F., Appleton, I., Darlington, C. L., & Bilkey, D. K. (2004). Age-related changes in nitric oxide synthase and arginase in the rat prefrontal cortex. Neurobiology of Aging, 25(4), 547-552.

Liu, P., Smith, P. F., Appleton, I., Darlington, C. L., & Bilkey, D. K. (2004). Potential involvement of NOS and arginase in age-related behavioural impairments. Experimental Gerontology, 39(8), 1207-1222.

Numata, M., Fawcett, J. P., Rosengren, R. J., & Wanwimolruk, S. (2004). Ontogeny of hepatic microsomal 3-hydroxylation of quinine in Adélie Penguins. Comparative Biochemistry & Physiology Part C, 138, 53-58.

Smith, P. F. (2004). GW-1000 GW Pharmaceuticals. Current Opinion in Investigational Drugs, 5(7), 748-754.

Smith, P. F. (2004). Medicinal cannabis extracts for the treatment of multiple sclerosis. Current Opinion in Investigational Drugs, 5(7), 727-730.

Zheng, Y., Darlington, C. L., & Smith, P. F. (2004). Bilateral labyrinthectomy causes long-term deficit in object recognition in rat. NeuroReport, 15, 1913-1916.

Ashton, J. C., Gliddon, C. M., Darlington, C. L., & Smith, P. F. (2003). Effect of low body temperature during unilateral labyrinthectomy on vestibular compensation in the guinea pig. Acta Oto-Laryngologica, 123, 448-452.

Ashton, N. G., Kelly, P. A., & Ledingham, J. M. (2003). Effect of cross-fostering on blood pressure and renal function in the New Zealand genetically hypertensive rat. Clinical & Experimental Pharmacology & Physiology, 30, 820-826.

Beers, S. A., Buckland, A. G., Giles, N., Gelb, M. H., & Wilton, D. C. (2003). Effect of tryptophan insertions on the properties of the human group IIA phospholipase A2: Mutagenesis produces an enzyme with characteristics similar to those of the human group V phospholipase A2. Biochemistry, 42, 7326-7338. doi: 10.1021/bi0343222

Benians, A., Leaney, J. L., & Tinker, A. (2003). Agonist unbinding from receptor dictates the nature of deactivation kinetics of G protein-gated K+ channels. PNAS, 100(10), 6239-6244.

Benians, A., Leaney, J. L., Milligan, G., & Tinker, A. (2003). The dynamics of formulation and action of the ternary complex revealed in living cells using a G-protein-gated K+ channel as a biosensor. Journal of Biological Chemistry, 278(12), 10851-10858.

Chaulk, D., Wells, J., Evans, S., Jackson, D., & Corbett, D. (2003). Long-term effects of clomethiazole in a model of global ischemia. Experimental Neurology, 182(2), 476-482. doi: 10.1016/S0014-4886(03)00121-3

Darlington, C. L. (2003). Dexanabinol: A novel cannabinoid with neuroprotective properties. IDrugs, 6(10), 976-979.

Darlington, C. L., & Smith, P. F. (2003). Vestibulotoxicity following aminoglycoside antibiotics and its prevention. Current Opinion in Investigational Drugs, 4(7), 841-846.

Giles, N. M., Giles, G. I., Holley, J. E., Gutowski, N. J., & Jacob, C. (2003). Targeting oxidative stress-related diseases: Organochalcogen catalysts as redox sensitizers. Biochemical Pharmacology, 66(10), 2021-2028. doi: 10.1016/S0006-2952(03)00544-6

Gliddon, C. M., Darlington, C. L., & Smith, P. F. (2003). Activation of the hypothalamic-pituitary-adrenal axis following vestibular deafferentation in pigmented guinea pig. Brain Research, 964, 306-310.

Gliddon, C. M., Smith, P. F., & Darlington, C. L. (2003). Interaction between the hypothalamic-pituitary-adrenal axis and behavioural compensation following unilateral vestibular deafferentation. Acta Oto-Laryngologica, 123(9), 1013-1021.

Goodin, M. G., & Rosengren, R. J. (2003). Epigallocatechin gallate modulates CYP450 isoforms in the female Swiss-Webster mouse. Toxicological Sciences, 76, 262-270.

Gray, C., Nukada, H., Jackson, D. M., McMorran, P. D., Wu, A., & Ma, F. (2003). Neuroprotective effects of nitrone radical scavenger S-PBN on reperfusion nerve injury in rats. Brain Research, 982, 179-185.

Green, A. R., Ashwood, T., Odergren, T., & Jackson, D. M. (2003). Nitrones as neuroprotective agents in cerebral ischemia, with particular reference to NXY-059. Pharmacology & Therapeutics, 100, 195-214.

Horii, A., Kitahara, T., Smith, P. F., Darlington, C. L., Masumura, C., & Kubo, T. (2003). Effects of unilateral labyrinthectomy on GAD, GATI and GABA receptor gene expression in the rat vestibular nucleus. NeuroReport, 14, 2359-2363.

Lees, G., & Kumar, A. (2003). Voltage gated sodium channels. CPD Anaesthesia, 5(2), 72-75. Retrieved from http://www.rila.co.uk/site/modules.php?name=Journals&file=journal2&func=showab&jid=027&aid=2932&iid=304

Liu, P., Bilkey, D. K., Darlington, C. L., & Smith, P. F. (2003). Cannabinoid CB1 receptor protein expression in the rat hippocampus and entorhinal, perirhinal, postrhinal and temporal cortices: Regional variations and age-related changes. Brain Research, 979(1-2), 235-239.

Liu, P., Smith, P. F., Appleton, I., Darlington, C. L., & Bilkey, D. K. (2003). Nitric oxide synthase and arginase in the rat hippocampus and the entorhinal, perirhinal, postrhinal, and temporal cortices: Regional variations and age-related changes. Hippocampus, 13, 859-867.

Liu, P., Smith, P. F., Appleton, I., Darlington, C. L., & Bilkey, D. K. (2003). Regional variations and age-related changes in nitric oxide synthase and arginase in the sub-regions of the hippocampus. Neuroscience, 119(3), 679-687.

Liu, P., Zheng, Y., King, J., Darlington, C. L., & Smith, P. F. (2003). Long-term changes in hippocampal N-methyl-D-aspartate receptor subunits following unilateral vestibular damage in rat. Neuroscience, 117, 965-970.

Liu, P., Zheng, Y., King, J., Darlington, C. L., & Smith, P. F. (2003). Nitric oxide synthase and arginase expression in the vestibular nucleus and hippocampus following unilateral vestibular deafferentation in the rat. Brain Research, 966, 19-25.

Liu, P., Zheng, Y., Smith, P. F., & Bilkey, D. K. (2003). Changes in NOS protein expression and activity in the rat hippocampus, entorhinal and postrhinal cortices after unilateral electrolytic perirhinal cortex lesions. Hippocampus, 13, 561-571.

Maclennan, K. M., Zheng, Y., Sheard, P. W., Williams, S. M., Darlington, C. L., & Smith, P. F. (2003). Adrenalectomy-induced cell death in the dentate gyrus: Further characterisation using TUNEL and effects of the Ginkgo biloba extract, EGb 761 and ginkgolide B. Hippocampus, 13, 212-225.

Mohammed, N. A., Abd-El-Aleem, S., Appleton, I., Maklouf, M. M., Said, M., & McMahon, R. F. T. (2003). Expression of nitric oxide synthase isoforms in human liver cirrhosis. Journal of Pathology, 200(5), 647-655. doi: 10.1002/path.1377

Nicholson, R. A., Liao, C., Zheng, J., David, L. S., Coyne, L., Errington, A. C., … Lees, G. (2003). Sodium channel inhibition by anandamide and synthetic cannabimimetics in brain. Brain Research, 978(1-2), 194-204.

Russell, N. A., Horii, A., Smith, P. F., Darlington, C. L., & Bilkey, D. K. (2003). Bilateral peripheral vestibular lesions produce long-term changes in spatial learning in the rat. Journal of Vestibular Research, 13(1), 9-16.

Russell, N. A., Horii, A., Smith, P. F., Darlington, C. L., & Bilkey, D. K. (2003). Long-term effects of permanent vestibular lesions on hippocampal spatial firing. Journal of Neuroscience, 23(16), 6490-6498.

Sammut, I. A., & Harrison, J. C. (2003). Cardiac mitochondrial complex activity is enchanced by heat shock proteins. Clinical & Experimental Pharmacology & Physiology, 30, 110-115.

Smith, P. F. (2003). Cannabinoids for the treatment of multiple sclerosis: No smoke without fire? Expert Review of Neurotherapeutics, 3(3), 327-334.

Smith, P. F. (2003). Neuroprotection against hypoxia-ischemia by insulin-like growth factor-I (IGF-I). IDrugs, 6(12), 1173-1177.

Smith, P. F. (2003). Therapeutic N-methyl-D-aspartate receptor antagonists: Will reality meet expectation. Current Opinion in Investigational Drugs, 4(7), 826-832.

Zheng, Y., Kerr, D. S., Darlington, C. L., & Smith, P. F. (2003). Unilateral inner ear damage results in lasting changes in hippocampal CA1 field potentials in vitro. Hippocampus, 13, 873-878.

Zheng, Y., Smith, P. F., Pearce, J. M., Vann, S. D., Good, M., Jenkins, T. A., & Aggleton, J. P. (2003). Using idiothetic cues to swim a path with a fixed trajectory and distance: Necessary involvement of the hippocampus, but not the retrosplenial cortex. Behavioral Neuroscience, 117(6), 1363-1377.

Bray, B. J., Brennan, N. J., Perry, N. B., Menkes, D. B., & Rosengren, R. J. (2002). Short term treatment with St John's wort, hypericin or hyperforin fails to induce CYP450 isoforms in the Swiss Webster mouse. Life Sciences, 70, 1325-1335.

Bray, B. J., Perry, N. B., Menkes, D. B., & Rosengren, R. J. (2002). St John's Wort extract induces CYP3A and CYP2E1 in the Swiss Webster Mouse. Toxicological Sciences, 66, 27-33.

Darlington, C. L., Dutia, M. B., & Smith, P. F. (2002). The contribution of the intrinsic properties of vestibular nucleus neurones to recovery from vestibular damage. European Journal of Neuroscience, 15, 1719-1727.

Farquhar, S., Fawcett, J. P., & Fountain, J. (2002). Illicit intravenous use of methylphenidate (Ritalin) tablets: A review of four cases. Australasian Emergency Nursing Journal, 5(2), 25-29.

Goodin, M. G., Fertuck, K. C., Zacharewski, T. R., & Rosengren, R. J. (2002). Estrogen receptor-mediated actions of Polyphenolic Catechins in vivo and in vitro. Toxicological Sciences, 69, 354-361.

Goodin, M. G., Walker, R. J., & Rosengren, R. J. (2002). Renal PGE2 production in the human and rat following phenactin, acetaminophen and p-aminophenol. Research Communications in Molecular Pathology & Pharmacology, 111, 153-166.

Horii, A., Smith, P. F., & Darlington, C. L. (2002). Application of real-time quantitative polymerase chain reaction to quantification of glutamate receptor gene expression in the vestibular brainstem and cerebellum. Brain Research Protocols, 9(1), 77-83. doi: 10.1016/S1385-299X(01)00139-8

Kerr, D. S., Razak, A., & Crawford, N. (2002). Age-related changes in tolerance to the marine algal excitotoxin domoic acid. Neuropharmacology, 43(3), 357-366.

King, J., Young, C., Highton, J., Smith, P. F., & Darlington, C. L. (2002). Vestibulo-ocular, optokinetic and postural function in humans with rheumatoid arthritis. Neuroscience Letters, 328, 77-80.

King, J., Zheng, Y., Liu, P., Darlington, C. L., & Smith, P. F. (2002). NMDA and AMPA receptor subunit protein expression in the rat vestibular nucleus following unilateral labyrinthectomy. NeuroReport, 13(12), 1541-1545.

Le Nedelec, M. J., & Rosengren, R. J. (2002). Methylphenidate inhibits cytochrome P450 in the Swiss Webster mouse. Human & Experimental Toxicology, 21, 273-280.

Leaney, J. L., Benians, A., Graves, F. M., & Tinker, A. (2002). A novel strategy to engineer functional fluorescent inhibitory G-protein α subunits. Journal of Biological Chemistry, 277(32), 28803-28809.

Ledingham, J. M., & Laverty, R. (2002). Fluvastatin remodels resistance arteries in genetically hypertensive rats even in the absence of any effect on blood pressure. Clinical & Experimental Pharmacology & Physiology, 29, 931-934.

Liu, H., Ledingham, J. M., Mullaney, I., & Laverty, R. (2002). Endothelial function in mesenteric resistance arteries from the genetically hypertensive rat. Clinical & Experimental Pharmacology & Physiology, 29, 405-411.

Liu, P., & Bilkey, D. (2002). The effects of NMDA lesions centered on the postrhinal cortex on spatial memory tasks in the rat. Behavioral Neuroscience, 116, 860-873.

Maclennan, K. M., Darlington, C. L., & Smith, P. F. (2002). The CNS effects of Ginkgo biloba extracts and ginkgolide B. Progress in Neurobiology, 67, 235-257.

Nicholson, M., King, J., Smith, P. F., & Darlington, C. L. (2002). Vestibulo-ocular, optokinetic and postural function in diabetes mellitus. NeuroReport, 13(1), 1-5.

Smith, P. F. (2002). The therapeutic applications of cannabinoids in the treatment of pain and spasticity in multiple sclerosis. Current Opinion in Investigational Drugs, 3, 1472-1477.

Suzuki, K., Murtuza, B., Sammut, I. A., Latif, N., Jayakumar, J., Smolenski, R. T., … Yacoub, M. (2002). Heat shock protein 72 enhances manganese superoxide dismutase activity during myocardial ischemia reperfusion injury, associated with mitochondrial protection and apoptosis reduction. Circulation, 106, 270-276.

Tasker, R. A. R., Bernard, P., Doucette, T. A., Kerr, D. S., Zabidin, Y., Alvarez Fernandez, L., … Novelli, A. (2002). Comparison of the in vitro and in vivo neurotoxicity of three new sources of kainic acid. Amino Acids, 23, 1-10.

Abd-El-Aleem, S. A., Ferguson, M. W. J., Appleton, I., Bhowmick, A., Jones, K., McCollum, C. N., & Ireland, G. W. (2001). Expression of cyclooxygenase isoforms in normal human skin and chronic venous ulcers. Journal of Pathology, 195(5), 616-623.

Bray, B. J., & Rosengren, R. J. (2001). Retinol potentiates acetaminophen-induced hepatotoxicity in the mouse: Mechanistic studies. Toxicology & Applied Pharmacology, 173, 129-136.

Bray, B. J., Goodin, M. G., Inder, R. E., & Rosengren, R. J. (2001). Retinol's effect on hepatic and renal drug metabolising enzymes. Food & Chemical Toxicology, 39, 1-9.

Clark, D. W., Layton, D., & Shakir, S. A. W. (2001). Monitoring the safety of over the counter drugs. British Medical Journal, 323, 706-707.

Clark, D. W., Layton, D., Wilton, L. V., Pearce, G., & Shakir, S. A. W. (2001). Profiles of hepatic and dysrhythmic cardiovascular events following use of fluoroquinolone antibacterials: experience from large cohorts from the Drug Safety Research Unit Prescription-Event Monitoring database. Drug Safety, 24(15), 1143-1154.

Darlington, C. L., Ross, A., King, J., & Smith, P. F. (2001). Menstrual cycle effects on postural stability but not optokinetic function. Neuroscience Letters, 307, 147-150.

Green, A. R., Hainsworth, A. H., Misra, T. R., Debens, T. A., Jackson, D. M., Murray, T. K., … Cross, A. J. (2001). The interaction of AR-AOO8055 and its enantiomers with the GABAA receptor complex and their sedative, muscle relaxant and anticonvulsant activity. Neuropharmacology, 41, 167-174.

Horii, A., Smith, P. F., & Darlington, C. L. (2001). Quantitative changes in gene expression of glutamate receptor subunits/subtypes in the vestibular nucleus, inferior olive and flocculus before and following unilateral labyrinthectomy in the rat: Real-time quantitative PCR method. Experimental Brain Research, 139, 188-200.

Jayakumar, J., Suzuki, K., Sammut, I. A., Smolenski, R. T., Khan, M., Latif, N., … Yacoub, M. (2001). Heat shock protein 70 gene transfection protects mitochondrial and ventricular function against ischemia-reperfusion injury. Circulation, 104, I303-I307.

Jude, E., Tentolouris, N., Appleton, I., Anderson, S., & Boulton, A. J. (2001). Role of neuropathy and plasma nitric oxide in recurrent neuropathic and neuroischaemic foot ulcers. Wound Repair & Regeneration, 9, 353-359.

Layton, D., Clark, D. W. J., Pearce, G. L., & Shakir, S. A. W. (2001). Is there an association between selective serotonin reuptake inhibitors and risk of abnormal bleeding? Results from a cohort study based on prescription event monitoring in England. European Journal of Clinical Pharmacology, 57, 167-176.

Ledingham, J. M., & Laverty, R. (2001). Effects of NOS inhibition and low salt diet on blood pressure and mesenteric resistance artery remodeling in genetically hypertensive (GH) rats. Clinical & Experimental Pharmacology & Physiology, 28, 761-763.

McLaughlin, C. W., Peart, D., Purves, R. D., Carre, D. A., Peterson-Yantorno, K., Mitchell, C. H., Macknight, A. D. C., & Civan, M. M. (2001). Timolol may inhibit aqueous humor secretion by cAMP-independent action on ciliary epthelial cells. American Journal of Physiology: Cell Physiology, 281, 865-875.

McLaughlin, C. W., Zellhuber-McMillan, S., Peart, D., Purves, R. D., Macknight, A., & Civan, M. (2001). Regional differences in ciliary epithelial cell transport properties. Journal of Membrane Biology, 182, 213-222.

Patel, R., & Rosengren, R. J. (2001). Acetaminophen elicits anti-estrogenic but not estrogenic responses in the immature mouse model. Toxicology Letters, 122, 89-96.

Perry, N. B., Aiyaz, M., Kerr, D. S., Lake, R. J., & Leach, M. (2001). NOESY on neurotoxins: NMR and conformational assignments of picrotoxanes. Phytochemical Analysis, 12, 69-72.

Russell, B. R., & Laverty, R. (2001). The effect of (R)-HA966 or ACEA 1021 on dexfenfluramine or (S)-MDMA-induced changes in temperature, activity and neurotoxicity. Pharmacology Biochemistry & Behavior, 68(3), 565-574. doi: 10.1016/S0091-3057(01)00454-3

Sammut, I. A., Jayakumar, J., Latif, N., Rothery, S., Severs, N., Smolenski, R. T., … Yacoub, M. (2001). Heat stress contributes to the enhancement of cardiac mitochondrial complex activity. American Journal of Pathology, 158(5), 1821-1831.

Sari, P., & Kerr, D. S. (2001). Domoic acid-induced hippocampal CA1 hyperexcitability independent of region CA3 activity. Epilepsy Research, 47, 65-76.

Smith, N. A., & Temple, W. A. (2001). Poisons. Absinthe - l'heure verte. Australian Pharmacist, 20(9), 590.

Smith, P. F. (2001). New evidence that nicotine affects eye movement and balance in susceptible individuals. NeuroReport, 12, A31-A32.

Smith, P. F., Zheng, Y., Paterson, S., & Darlington, C. L. (2001). The contribution of nitric oxide to vestibular compensation: Are there species differences? Acta Oto-Laryngologica, 121(545), 57-60. doi: 10.1080/000164801750388126

Smolenski, R. T., Amrani, M., Jayakumar, J., Jagodzinski, P., Gray, C., Goodwin, A. T., Sammut, I. A., & Yacoub, M. (2001). Pyruvate/dichloroacetate supply during reperfusion accelerates recovery of energy equilibrium and improves mechanical function following cardioplegic arrest. European Journal of Cardio-Thoracic Surgery, 19, 865-872.

Suzuki, K., Murtuza, B., Smolenski, R. T., Sammut, I. A., Suzuki, N., Kaneda, Y., & Yacoub, M. (2001). Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with a reduction in apoptosis. Circulation, 104, I308-I313.

Suzuki, K., Murtuza, B., Smolenski, R. T., Sammut, I. A., Suzuki, N., Kaneda, Y., & Yacoub, M. (2001). Cell transplantation for the treatment of acute myocardial infarction using vascular-endothelial growth factor-expressing skeletal myoblasts. Circulation, 104, I207-I212.

Todd, L., King, J., Darlington, C. L., & Smith, P. F. (2001). Optokinetic reflex dysfunction in multiple sclerosis. NeuroReport, 12(7), 1399-1402.

Zheng, Y., Horii, A., Appleton, I., Darlington, C. L., & Smith, P. F. (2001). Damage to the vestibular inner ear causes long-term changes in nitric oxide synthase expression in the rat hippocampus. Neuroscience, 105(1), 1-5.

Zheng, Y., Horii, A., Smith, P. F., & Darlington, C. L. (2001). Differences in NOS protein expression and activity in the rat vestibular nucleus following unilateral labyrinthectomy. Molecular Brain Research, 88, 166-170.

Abd-El-Aleem, S., Ferguson, M. W. J., Appleton, I., Kairsingh, S., Jude, E. B., Jones, K., … Ireland, G. W. (2000). Expression of nitric oxide synthase isoforms and arginase in normal human skin and chronic venous ulcers. Journal of Pathology, 191, 434-442.

Al-Samarrai, T. H., Zhang, N. X., Lamont, I. L., Martin, L., Kolbe, J., Wilsher, M., … Schmid, J. (2000). Simple and inexpensive but highly discriminating method of computer-assisted DNA fingerprinting of Pseudomonas aeruginosa. Journal of Clinical Microbiology, 38(12), 4445-4452.

Alexander, H., Sansom, A. J., Kerr, D. R., Smith, P. F., Dragunow, M., & Darlington, C. L. (2000). An antisense oligonucleotide for c-fos does not delay vestibular compensation of the static symptoms following unilateral vestibular deafferention in guinea pig. Neuroscience Research Communications, 26(2), 123-128.

Alexander, H., Sansom, A. J., Kerr, D. R., Smith, P. F., Dragunow, M., & Darlington, C. L. (2000). Effects of c-fos antisense and mis-sense oligonucleotides on Fos expression in the vestibular nucleus and vestibular compensation following unilateral labyrinthectomy. Neuroscience Research Communications, 26(2), 123-128.

Bray, B. J., Inder, R. E., & Rosengren, R. J. (2000). Retinol-mediated effects on the activation and detoxification pathways of paracetamol. Australasian Journal of Ecotoxicology, 6(2), 75-79.

Bray, M., & Ghose, K. (2000). Knowledge of, and attitude to, prescribed medications of patients with frequent headaches. Headache Quarterly, 11(1), 37-40.

Clark, D. W., Morgan, A., Hananeia, L., Coulter, D. M., & Olds, R. J. (2000). Drug metabolism genotypes and their association with adverse drug reactions in selected populations: A pilot study of methodology. Pharmacoepidemiology & Drug Safety, 9, 393-400.

Crawford, N., Lang, T. K., Kerr, D. S., & de Vries, D. J. (2000). High affinity [3H] kainic acid binding to brain membranes: A re-evaluation of ligand potency and selectivity. Journal of Pharmacological & Toxicological Methods, 42(3), 121-125.

Darlington, C. L., Erasmus, J., Nicholson, M., King, J., & Smith, P. F. (2000). Comparison of visual-vestibular interaction in insulin-dependent and non-insulin-dependent diabetes mellitus. NeuroReport, 11(3), 487-490.

Gliddon, C. M., Sansom, A. J., Smith, P. F., & Darlington, C. L. (2000). Effects of intra-vestibular nucleus injection of the Group I metabotropic glutamate receptor antagonist AIDA on vestibular compensation in guinea pigs. Experimental Brain Research, 134(1), 74-80. doi: 10.1007/s002210000437

Goodin, M. G., Walker, R. J., & Rosengren, R. J. (2000). The effect of low doses of paracetamol on prostaglandin E2 production in the human and rat kidney. Australasian Journal of Ecotoxicology, 6(2), 85-88.

Gowans, J., Matheson, A. J., Darlington, C. L., & Smith, P. F. (2000). The effects of scopolamine and cyclizine on visual-vestibular interaction in humans. Journal of Vestibular Research, 10, 87-92.

Green, A. R., Hainsworth, A. H., & Jackson, D. M. (2000). GABA potentiation: A logical pharmacological approach for the treatment of acute ischaemic stroke. Neuropharmacology, 39(9), 1483-1494. doi: 10.1016/S0028-3908(99)00233-6

Hargreaves, P., Bray, B. J., Hooser, S. B., & Rosengren, R. J. (2000). Nodular-induced fatalities result from necrosis, not apoptosis in the male Swiss Webster mouse. Australasian Journal of Ecotoxicology, 6(1), 65-69.

Ho, P.-C., Ghose, K., Saville, D. J., Coville, P., & Wanwimolruk, S. (2000). Effect of grapefruit juice on pharmacokinetics and pharmacodynamics of verapamil enantiomers in healthy volunteers. European Journal of Clinical Pharmacology, 56, 693-698.

Ho, P.-C., Saville, D. J., & Wanwimolruk, S. (2000). Simultaneous HPLC analysis of verapamil and norverapamil enantiomers in human plasma and urine. Journal of Liquid Chromatography & Related Technologies, 23, 1711-1724.

Jayakumar, J., Suzuki, K., Khan, M., Smolenski, R. T., Latif, N., Raisky, O., Sammut, I. A., & Yacoub, M. H. (2000). Gene therapy for myocardial protection: Transfection of donor hearts with heart stress protein 70 gene protects cardiac function against ischaemia-reperfusion injury. Circulation, 102, 302-306.

Kerr, D. R., Sansom, A. J., Smith, P. F., & Darlington, C. L. (2000). Comparison of protein kinase activity and protein phosphorylation in the medial vestibular nucleus and prepositus hypoglossi in labyrinthine-intact and labyrinthectomized guinea pigs. Journal of Vestibular Research, 10(2), 107-117.

Lange, S., Niven, B., & Laing, R. M. (2000). Suitabiltity of leather for garments: Differences in selected properties attributable to processing and sampling location. Journal of the Society of Leather Technologists & Chemists, 84(1), 1-5.

Ledingham, J. M., & Laverty, R. (2000). Basilar artery remodelling in the genetically hypertensive rat: effects of nitric oxide synthase inhibition and treatment with valsartan and enalapril. Clinical & Experimental Pharmacology & Physiology, 27, 642-646.

Ledingham, J. M., Phelan, E. L., Cross, M. A., & Laverty, R. (2000). Prevention of increases in blood pressure and left ventricular mass and remodeling of resistance arteries in young New Zealand genetically hypertensive (GH) rats: The effects of chronic treatment with valsartan, enalapril and felodipine. Journal of Vascular Research, 37, 134-145.

Macknight, A. D. C., McLaughlin, C. W., Peart, D., Purves, R. D., Carre, D. A., & Civan, M. M. (2000). Formation of the aqueous humor. Clinical & Experimental Pharmacology & Physiology, 27, 100-106.

Maingay, M., Sansom, A. J., Kerr, D. R., Smith, P. F., & Darlington, C. L. (2000). The effects of intra-vestibular nucleus administration of brain-derived neurotrophic factor (BDNF) on recovery from peripheral vestibular damage in guinea pig. NeuroReport, 11(11), 2429-2432.

Marshall, J. W. B., Cross, A. J., Jackson, D. M., Green, A. R., Ridley, R. M., & Baker, H. F. (2000). Clomethiazole protects against hemineglect in a primate model of stroke. Brain Research Bulletin, 52(1), 21-29.

Norris, W. R., Temple, W. A., Eason, C., Wright, G. R., Ataria, J., & Wickstrom, M. (2000). Sorption of fluoroacetate (compound 1080) by colestipol, activated charcoal and anion-exchange resins in vitro and gastrointestinal decontamination in rats. Veterinary & Human Toxicology, 42(5), 269-275.

Orange, S. J., Ledingham, J. M., & Laverty, R. (2000). Cardiovascular effects of chronic nitric oxide synthase inhibition in genetically hypertensive rats. Clinical & Experimental Pharmacology & Physiology, 27, 488-493.

Patel, R., & Rosengren, R. J. (2000). Oestrogenicity of pentachlorophen and paracetamol. Australasian Journal of Ecotoxicology, 6(2), 81-84.

Paterson, S., Zheng, Y., Smith, P. F., & Darlington, C. L. (2000). The effects of L-NAME on vestibular compensation and NOS activity in the vestibular nucleus, cerebellum and cortex of the guinea pig. Brain Research, 879, 148-155.

Peeling, J., Del Bigio, M. R., Corbett, D., Green, A. R., & Jackson, D. M. (2000). Efficacy of disudium 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (NXY-059), a free radical trapping agent, in a rat model of hemorrhagic stroke. Neuropharmacology, 40(3), 433-439. doi: 10.1016/S0028-3908(00)00170-2

Peters, K., Darlington, C. L., & Smith, P. F. (2000). The effects of repeated optokinetic stimulation on human autonomic function. Journal of Vestibular Research, 10, 139-142.

Russell, B. R., & Laverty, R. (2000). Correlation between 5-HT content and uptake site density following (S)-MDMA and dexfenfluramine-induced depletion, and with neuroprotection by the glycine site-specific NMDA antagonist ACEA 1021. Annals of the New York Academy of Sciences, 914, 208-214. doi: 10.1111/j.1749-6632.2000.tb05197.x

Sammut, I. A., Burton, K., Balogun, E., Sarathchandra, P., Brooks, K. J., Bates, T. E., & Green, C. J. (2000). Time-dependent impairment of mitochondrial function following kidney storage and transplantation. Transplantation, 69, 1265-1275.

Sansom, A. J., Smith, P. F., Darlington, C. L., & Laverty, R. (2000). The effects of protein kinase C and calmodulin kinase II inhibitors on vestibular compensation in the guinea pig. Brain Research, 882(1-2), 45-54.

Sansom, A. J., Smith, P. F., Darlington, C. L., & Laverty, R. (2000). Vestibular nucleus N-methyl-D-aspartate receptors contribute to spontaneous nystagmus generation following unilateral labyrinthectomy in guinea pigs. Neuroscience Letters, 283(2), 117-120.

Smith, P. F. (2000). A neuroscientist looks at philosophy: Response to Beedle (1999). Journal of Neuroscience Research, 60, 281-283.

Smith, P. F. (2000). Are vestibular hair cells excited to death by aminoglycoside antibiotics? Journal of Vestibular Research, 10(1), 1-5.

Smith, P. F. (2000). Cannabis on the brain: Is it neurotoxic or neuroprotective? New Zealand Journal of Psychology, 29(1), 36-39.

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