2022

Journal - Research Article

Ooi, J. M. F., Fairhall, J. M., Spangler, B., Chong, D. J. W., Feng, B. Y., Gamble, A. B., & Hook, S. (2022). Development of a bioorthogonal fluorescence-based assay for assessing drug uptake and delivery in bacteria. RSC Advances, 12, 15631-15642. doi: 10.1039/d2ra02272a

Conference Contribution - Verbal presentation and other Conference outputs

Su, S., Hook, S., Pletzer, D., & Gamble, A. (2022, November). Overcoming efflux-mediated multidrug resistance in Pseudomonas aeruginosa. Verbal presentation at the School of Pharmacy Research Day, Dunedin, New Zealand.

Kok, L. K., Lawer, A., Li, S., Li, P., Gamble, A., & Hook, S. (2022, November). Universal CAR-T cell therapy using stimuli-responsive "tags" and "pro-tags". Verbal presentation at the School of Pharmacy Research Day, Dunedin, New Zealand.

Brind, T., Lawer, A., Todd, T., Hook, S., & Gamble, A. (2022, November). Dendrimer prodrugs: Manipulating electronics to aid prodrug design. Verbal presentation at the School of Pharmacy Research Day, Dunedin, New Zealand.

Rani, P., Dadhwal, S., Hook, S., & Gamble, A. B. (2022, November). Click-to-dissolve: Stimuli-responsive biopolymer-based thermoresponsive hydrogels for improved drug delivery. Verbal presentation at the School of Pharmacy Research Day, Dunedin, New Zealand.

Ross, C. L., Lawer, A., Sircombe, K. J., Mros, S., McConnell, M., Pletzer, D., Gamble, A. B., & Hook, S. (2022, November). Development of a dual prodrug for triggered antibiotic activation. Verbal presentation at the School of Pharmacy Research Day, Dunedin, New Zealand.

Fairhall, J. M., Ooi, J. M. F., Spangler, B., Chong, D. J. W., Feng, B. Y., Gamble, A. B., & Hook, S. (2022, November). A flurogenic bioorthogonal assay for determining drug uptake and delivery in bacteria. Invited presentation at the New Zealand Controlled Release Society (NZCRS) Symposium, Auckland, New Zealand.

Gamble, A., Dadhwal, S., Paterson, D. A., Rani, P., Fairhall, J., Fong, W.-K., & Hook, S. (2022, November). Stimuli-responsive polymers, polymeric particles, and hydrogels for drug delivery. Invited presentation at the New Zealand Controlled Release Society (NZCRS) Symposium, Auckland, New Zealand.

Kok, L. K., Lawer, A., Li, S., Li, P., Gamble, A., & Hook, S. (2022, August). Universal CAR-T cell therapy using stimuli-responsive "tags" and "pro-tags". Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

2021

Journal - Research Article

Paterson, D. A., Fong, W.-K., Hook, S., & Gamble, A. B. (2021). Hydrogen sulfide-responsive bicontinuous nanospheres. Biomacromolecules, 22, 4770-4782. doi: 10.1021/acs.biomac.1c01070

Naciute, M., Kiwitt, T., Kemp, R. A., & Hook, S. (2021). Bacteria biohybrid oral vaccines for colorectal cancer treatment reduce tumor growth and increase immune infiltration. Vaccine, 39, 5589-5599. doi: 10.1016/j.vaccine.2021.08.028

Fairhall, J. M., Camilli, J. C., Gibson, B. H., Hook, S., & Gamble, A. B. (2021). EGFR-targeted prodrug activation using bioorthogonal alkene-azide click-and-release chemistry. Bioorganic & Medicinal Chemistry, 46, 116361. doi: 10.1016/j.bmc.2021.116361

Dadhwal, S., Lee, A., Goswami, S. K., Hook, S., & Gamble, A. B. (2021). Synthesis and formulation of self-immolative PEG-aryl azide block copolymers and click-to-release reactivity with trans-cyclooctene. Journal of Polymer Science, 59, 646-658. doi: 10.1002/pol.20210020

Azhari, H., Younus, M., Hook, S. M., Boyd, B. J., & Rizwan, S. B. (2021). Cubosomes enhance drug permeability across the blood-brain barrier in zebrafish. International Journal of Pharmaceutics, 600, 120411. doi: 10.1016/j.ijpharm.2021.120411

Conference Contribution - Published proceedings: Abstract

Ross, C. L., Lawer, A., Sircombe, K., McConnell, M., Pletzer, D., Gamble, A., & Hook, S. (2021). Developing a dual prodrug for triggered antibiotic activation. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 244). Retrieved from https://www.faobmb2021.org

2020

Journal - Research Article

Fairhall, J. M., Murayasu, M., Dadhwal, S., Hook, S., & Gamble, A. B. (2020). Tuning activation and self-immolative properties of the bioorthogonal alkene-azide click-and-release strategy. Organic & Biomolecular Chemistry, 18, 4754-4762. doi: 10.1039/d0ob00936a

Naciute, M., Niemi, V., Kemp, R. A., & Hook, S. (2020). Lipid-encapsulated oral therapeutic peptide vaccines reduce tumour growth in an orthotopic mouse model of colorectal cancer. European Journal of Pharmaceutics & Biopharmaceutics, 153, 183-192. doi: 10.1016/j.ejpb.2020.04.020

Dadhwal, S., Fairhall, J. M., Hook, S., & Gamble, A. B. (2020). Tetrafluoroaryl azide as an N-terminal capping group for click-to-dissolve diphenylalanine hydrogels. RSC Advances, 10(16), 9234-9244. doi: 10.1039/d0ra01013h

Journal - Research Other

Bobbala, S., & Hook, S. (2020). Vaccine implants: Current status and recent advancements. Emerging Topics in Life Sciences, 4, 601-612. doi: 10.1042/etls20200164

2019

Journal - Research Article

Vu, H. T. H., Streck, S., Hook, S. M., & McDowell, A. (2019). Utilization of microfluidics for the preparation of polymeric nanoparticles for the antioxidant rutin: A comparison with bulk production. Pharmaceutical Nanotechnology, 7, 469-483. doi: 10.2174/2211738507666191019141049

von Halling Laier, C., Gibson, B., Moreno, J. A. S., Rades, T., Hook, S., Nielsen, L. H., & Boisen, A. (2019). Microcontainers for protection of oral vaccines, in vitro and in vivo evaluation. Journal of Controlled Release, 294, 91-101. doi: 10.1016/j.jconrel.2018.11.030

Dadhwal, S., Fairhall, J. M., Goswami, S. K., Hook, S., & Gamble, A. B. (2019). Alkene-azide 1,3-dipolar cycloaddition as a trigger for ultrashort peptide hydrogel dissolution. Chemistry: An Asian Journal, 14, 1143-1150. doi: 10.1002/asia.201801184

2018

Journal - Research Article

Cooper, A. G., Oyagawa, C. R. M., Manning, J. J., Singh, S., Hook, S., Grimsey, N. L., Glass, M., Tyndall, J. D. A., & Vernall, A. J. (2018). Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1,8-naphthyridin-2-(1H)-one-3-carboxamide scaffold. MedChemComm, 9(12), 2055-2067. doi: 10.1039/c8md00448j

Vu, H. T. H., Hook, S. M., Siqueira, S. D., Müllertz, A., Rades, T., & McDowell, A. (2018). Are phytosomes a superior nanodelivery system for the antioxidant rutin? International Journal of Pharmaceutics, 548(1), 82-91. doi: 10.1016/j.ijpharm.2018.06.042

Bobbala, S., Gibson, B., Gamble, A. B., McDowell, A., & Hook, S. (2018). Poloxamer 407-chitosan grafted thermoresponsive hydrogels achieve synchronous and sustained release of antigen and adjuvant from single-shot vaccines. Immunology & Cell Biology, 96(6), 656-665. doi: 10.1111/imcb.12031

Matikonda, S. S., Fairhall, J. M., Fiedler, F., Sanhajariya, S., Tucker, R. A. J., Hook, S., Garden, A. L., & Gamble, A. B. (2018). Mechanistic evaluation of bioorthogonal decaging with trans-cyclooctene: The effect of fluorine substituents on aryl azide reactivity and decaging from the 1,2,3-triazoline. Bioconjugate Chemistry, 29(2), 324-334. doi: 10.1021/acs.bioconjchem.7b00665

Cooper, A. G., MacDonald, C., Glass, M., Hook, S., Tyndall, J. D. A., & Vernall, A. J. (2018). Alkyl indole-based cannabinoid type 2 receptor tools: Exploration of linker and fluorophore attachment. European Journal of Medicinal Chemistry, 145, 770-789. doi: 10.1016/j.ejmech.2017.11.076

Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2018). Characterization and evaluation of stabilized particulate formulations as therapeutic oral vaccines for allergy. Journal of Liposome Research, 28(4), 296-304. doi: 10.1080/08982104.2017.1370472

Conference Contribution - Published proceedings: Abstract

Dadhwal, S., Lee, K., Hook, S., & Gamble, A. B. (2018). Stimuli-responsive delivery of drug to tumour improves the survival in a mouse model. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Naciute, M., Niemi, G., Gibson, B., Kemp, R., & Hook, S. (2018). Oral therapeutic vaccination against colorectal cancer. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Harte, J., Niemi, G., Hook, S., & Kemp, R. (2018). Detection of AH1 antigen specific T cells in a murine colorectal cancer model. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Gaskarth, D., Niemi, G., Highton, A., Hook, S., & Kemp, R. (2018). Characterising T cell response in an orthotopic intracaecal mouse model of colorectal cancer. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Niemi, G. R., Highton, A. J., Hook, S. M., & Kemp, R. A. (2018). Modulating the immune response to colorectal cancer in mice using a cancer vaccine. New Zealand Medical Journal, 131(1470), (pp. 111). Retrieved from https://www.nzma.org.nz/journal

Conference Contribution - Poster Presentation (not in published proceedings)

Vu, H. T. H., Hook, S. M., Horsfield, J. A., & McDowell, A. (2018, August). Comparison of the uptake of rutin-loaded nanoparticles in a zebrafish model. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Dadhwal, S., Lee, K., Hook, S., & Gamble, A. B. (2018, August). Stimuli-responsive delivery of drug to tumor improves the survival in a mouse model. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Matikonda, S. S., Fairhall, J. M., Dadhwal, S., Gibson, B., Garden, A., Hook, S., & Gamble, A. B. (2018, August). Bioorthogonal prodrug activation. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Gaskarth, D. A., Niemi, G. R., Highton, A., Hook, S., & Kemp, R. A. (2018, August). Characterising T cell responses in an orthotopic intracaecal mouse model of colorectal cancer. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Naciute, M., Niemi, G., Gibson, B., Kemp, R., & Hook, S. (2018, August). Immune response to oral therapeutic vaccination against colorectal cancer. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

2017

Journal - Research Article

Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2017). Liposomal α-galactosylceramide is taken up by gut-associated lymphoid tissue and stimulates local and systemic immune responses. Journal of Pharmacy & Pharmacology, 69(12), 1724-1735. doi: 10.1111/jphp.12814

Cooper, A., Singh, S., Hook, S., Tyndall, J. D. A., & Vernall, A. J. (2017). Chemical tools for studying lipid-binding class A G protein-coupled receptors. Pharmacological Reviews, 69(3), 316-353. doi: 10.1124/pr.116.013243

Umair, S., Pernthaner, A., Deng, Q., Gibson, B., Hook, S., & Heath, D. (2017). Preliminary evaluation of a thermosensitive chitosan hydrogel for Echinococcus granulosus vaccine delivery. Veterinary Parasitology, 236, 117-120. doi: 10.1016/j.vetpar.2017.02.007

Even, M.-P., Bobbala, S., Gibson, B., Hook, S., Winter, G., & Engert, J. (2017). Twin-screw extruded lipid implants containing TRP2 peptide for tumour therapy. European Journal of Pharmaceutics & Biopharmaceutics, 114, 79-87. doi: 10.1016/j.ejpb.2016.12.033

Matikonda, S. S., Fairhall, J. M., Tyndall, J. D. A., Hook, S., & Gamble, A. B. (2017). Stability, kinetic, and mechanistic investigation of 1,8-self-immolative cinnamyl ether spacers for controlled release of phenols and generation of resonance and inductively stabilized methides. Organic Letters, 19(3), 528-531. doi: 10.1021/acs.orglett.6b03695

Conference Contribution - Published proceedings: Abstract

Niemi, G., Hook, S., & Kemp, R. (2017). Comparison of immune cell infiltrate between subcutaneous melanoma and colon carcinoma mouse models. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 62-63). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html

Niemi, G., Naciute, M., Highton, A., Gibson, B., Hook, S., & Kemp, R. (2017). Altering the immune response to colorectal cancer in mouse models. Proceedings of the 46th Australasian Society for Immunology (ASI) Annual Scientific Meeting. 341. Retrieved from http://www.asi2017.org/

Lee, K., Dadhwal, S., Gibson, B., Gamble, A., & Hook, S. (2017). Membrane-modified liposomes for vaccine delivery. Proceedings of the 46th Australasian Society for Immunology (ASI) Annual Scientific Meeting. 256. Retrieved from http://www.asi2017.org/

Gamble, A. B., Matikonda, S. S., Fairhall, J. M., Fiedler, F., Sanhajariya, S., Tucker, R., & Hook, S. (2017). Bioothogonal prodrug activation. Proceedings of the Royal Australian Chemical Institute (RACI) Centenary Congress. (pp. 4). Retrieved from http://www.racicongress.com/

Niemi, V. R., Highton, A. J., Hook, S. M., & Kemp, R. A. (2017). Comparison of immune cell infiltrate between subcutaneous melanoma and colon carcinoma mouse models. New Zealand Medical Journal, 130(1452), (pp. 78). Retrieved from https://www.nzma.org.nz/journal

Conference Contribution - Poster Presentation (not in published proceedings)

Cooper, A., Macdonald, C., Manning, J., Glass, M., Hook, S., Tyndall, J., & Vernall, A. (2017, September). Design, synthesis and pharmacological evaluation of fluorescent ligands as tools for studying cannabinoid type 2 receptor. Poster session presented at the 19th RSC/SCI Medicinal Chemistry Symposium, Cambridge, UK.

2016

Journal - Research Article

Gauld, N. J., Braganza, C., Babalola, O. O., Huynh, T. T., & Hook, S. M. (2016). Reasons for use and non-use of the pertussis vaccine during pregnancy: An interview study. Journal of Primary Health Care, 8(4), 344-350. doi: 10.1071/HC15049

Neumann, S., Shirley, S. A., Kemp, R. A., & Hook, S. M. (2016). Improved antitumor activity of a therapeutic melanoma vaccine through the use of the dual COX-2/5-LO inhibitor licofelone. Frontiers in Immunology, 7(537), 537. doi: 10.3389/fimmu.2016.00537

Highton, A. J., Girardin, A., Bell, G. M., Hook, S. M., & Kemp, R. A. (2016). Chitosan gel vaccine protects against tumour growth in an intracaecal mouse model of cancer by modulating systemic immune responses. BMC Immunology, 17, 39. doi: 10.1186/s12865-016-0178-4

Subharat, S., Shu, D., Zheng, T., Buddle, B. M., Kaneko, K., Hook, S., … Wedlock, D. N. (2016). Vaccination of sheep with a methanogen protein provides insight into levels of antibody in saliva needed to target ruminal methanogens. PLoS ONE, 11(7), e0159861. doi: 10.1371/journal.pone.0159861

Bobbala, S., & Hook, S. (2016). Is there an optimal formulation and delivery strategy for subunit vaccines? Pharmaceutical Research, 33(9), 2078-2097. doi: 10.1007/s11095-016-1979-0

Azhari, H., Strauss, M., Hook, S., Boyd, B. J., & Rizwan, S. B. (2016). Stabilising cubosomes with Tween 80 as a step towards targeting lipid nanocarriers to the blood-brain barrier. European Journal of Pharmaceutics & Biopharmaceutics, 104, 148-155. doi: 10.1016/j.ejpb.2016.05.001

Bobbala, S., Tamboli, V., McDowell, A., Mitra, A. K., & Hook, S. (2016). Novel injectable pentablock copolymer based thermoresponsive hydrogels for sustained release vaccines. AAPS Journal, 18(1), 261-269. doi: 10.1208/s12248-015-9843-4

Conference Contribution - Published proceedings: Abstract

Lee, K., Gamble, A., & Hook, S. (2016). Modified liposomes for the delivery of cancer vaccines to the cytosol of antigen presenting cells through the proton sponge effect. European Journal of Immunology, 46(Suppl. 1), (pp. 1228). doi: 10.1002/eji.201670200

Bobbala, S., Gibson, B., & Hook, S. (2016). Is the sustained release of vaccine antigens beneficial or detrimental to the development of immunity? European Journal of Immunology, 46(Suppl. 1), (pp. 811-812). doi: 10.1002/eji.201670200

Highton, A., Niemi, V., Hook, S., & Kemp, R. (2016). Chitosan hydrogel vaccine generates CD8⁺ T cell memory protective in a mouse tumour model of colorectal cancer. European Journal of Immunology, 46(Suppl. 1), (pp. 201). doi: 10.1002/eji.201670200

Azhari, H., Hook, S., Boyd, B., & Rizwan, S. (2016). Formulation and uptake of cationic cubosomes in the zebrafish brain. Proceedings of the Drug Delivery Australia Conference. (pp. 70). Retrieved from http://www.crsaustralia.org/

Vu, H. T. H., Hook, S. M., Rades, T., & McDowell, A. (2016). Characterization of phytosomes for the delivery of the antioxidant rutin. Proceedings of the Drug Delivery Australia Conference. (pp. 55). Retrieved from http://www.crsaustralia.org/

Dadhwal, S., Lee, A., Goswami, S., Hook, S., & Gamble, A. B. (2016). Bioorthogonal triggered responsive polymersomes for anticancer drug delivery. Proceedings of the Diagnostics, Drugs, Devices, Discovery (D4) Conference. Retrieved from http://www.otago.ac.nz/d4/index.html

Vu, H. T. H., Hook, S., & McDowell, A. (2016). Do phytosomes improve the stability of the antioxidant rutin for oral delivery? Proceedings of the Diagnostics, Drugs, Devices, Discovery (D4) Conference. Retrieved from http://www.otago.ac.nz/d4/index.html

Cooper, A. G., Macdonald, C., Glass, M., Hook, S., Tyndall, J. D. A., & Vernall, A. J. (2016). Development of tools for studying cannabinoid type 2 receptor: Design, synthesis and pharmacological evaluation of fluorescent ligands and intermediates. Proceedings of the Diagnostics, Drugs, Devices, Discovery (D4) Conference. Retrieved from http://www.otago.ac.nz/d4/index.html

Cooper, A. G., Macdonald, C., Glass, M., Hook, S., Tyndall, J. D. A., & Vernall, A. J. (2016). Development of fluorescent ligands as tools for studying cannabinoid type 2 receptor. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and the Molecular Pharmacology of G Protein-Coupled Receptors (ASCEPT-MPGPCR) Joint Scientific Meeting. 709. Retrieved from http://www.asceptasm.com/

Conference Contribution - Poster Presentation (not in published proceedings)

Cooper, A. G., Macdonald, C., Glass, M., Hook, S., Tyndall, J. D. A., & Vernall, A. J. (2016, August-September). Development of fluorescent ligands as tools for studying cannabinoid type 2 receptor. Poster session presented at the European Federation for Medicinal Chemistry (EFMC) International Symposium on Medicinal Chemistry, Manchester, UK.

Conference Contribution - Verbal presentation and other Conference outputs

Vu, H. T. H., Hook, S., & McDowell, A. (2016, July). Phytosomes: A nanoformulation to improve the solubility of rutin. Verbal presentation at the Controlled Release Society (CRS) 43rd Annual Meeting & Exposition, Seattle, WA.

2015

Edited Book - Research

Foged, C., Rades, T., Perrie, Y., & Hook, S. (Eds.). (2015). Subunit vaccine delivery. New York: Springer. doi: 10.1007/978-1-4939-1417-3

Chapter in Book - Research

Rattanapak, T., Foged, C., & Hook, S. (2015). Transcutaneous immunization. In C. Foged, T. Rades, Y. Perrie & S. Hook (Eds.), Subunit vaccine delivery. (pp. 347-369). New York: Springer. doi: 10.1007/978-1-4939-1417-3

Journal - Research Article

Liau, J. J., Hook, S., Prestidge, C. A., & Barnes, T. J. (2015). A lipid based multi-compartmental system: Liposomes-in-double emulsion for oral vaccine delivery. European Journal of Pharmaceutics & Biopharmaceutics, 97, 15-21. doi: 10.1016/j.ejpb.2015.09.018

Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2015). Selective quantitation of the incorporation of the immunomodulator α-galactosylceramide in liposomes using LC-MS/MS. International Journal of Mass Spectrometry, 392, 96-101. doi: 10.1016/j.ijms.2015.09.016

Greatrex, B. W., Daines, A. M., Hook, S., Lenz, D. H., McBurney, W., Rades, T., & Rendle, P. M. (2015). Synthesis, formulation, and adjuvanticity of monodesmosidic saponins with olenanolic acid, hederagenin and gypsogenin aglycones, and some C-28 ester derivatives. ChemistryOpen, 4(6), 740-755. doi: 10.1002/open.201500149

Neumann, S., Young, K., Compton, B., Anderson, R., Painter, G., & Hook, S. (2015). Synthetic TRP2 long-peptide and α-galactosylceramide formulated into cationic liposomes elicit CD8⁺ T-cell responses and prevent tumour progression. Vaccine, 33, 5838-5844. doi: 10.1016/j.vaccine.2015.08.083

Even, M.-P., Bobbala, S., Kok, L. K., Hook, S., Winter, G., & Engert, J. (2015). Impact of implant composition of twin-screw extruded lipid implants on the release behavior. International Journal of Pharmaceutics, 493, 102-110. doi: 10.1016/j.ijpharm.2015.06.052

Engelke, L., Winter, G., Hook, S., & Engert, J. (2015). Recent insights into cutaneous immunization: How to vaccinate via the skin. Vaccine, 33, 4663-4674. doi: 10.1016/j.vaccine.2015.05.012

Highton, A. J., Kojarunchitt, T., Girardin, A., Hook, S., & Kemp, R. A. (2015). Chitosan hydrogel vaccine generates protective CD8 T cell memory against mouse melanoma. Immunology & Cell Biology, 93, 634-640. doi: 10.1038/icb.2015.14

Scherließ, R., Mönckedieck, M., Young, K., Trows, S., Buske, S., & Hook, S. (2015). First in vivo evaluation of particulate nasal dry powder vaccine formulations containing ovalbumin in mice. International Journal of Pharmaceutics, 479(2), 408-415. doi: 10.1016/j.ijpharm.2015.01.015

Kojarunchitt, T., Baldursdottir, S., Dong, Y.-D., Boyd, B. J., Rades, T., & Hook, S. (2015). Modified thermoresponsive Poloxamer 407 and chitosan sol-gels as potential sustained-release vaccine delivery systems. European Journal of Pharmaceutics & Biopharmaceutics, 89, 74-81. doi: 10.1016/j.ejpb.2014.11.026

Bobbala, S., McDowell, A., & Hook, S. (2015). Quantitation of the immunological adjuvants, monophosphoryl lipid A and Quil A in poly (lactic-co-glycolic acid) nanoparticles using high performance liquid chromatography with evaporative light scattering detection. Journal of Chromatography B, 975, 45-51. doi: 10.1016/j.jchromb.2014.11.006

Conference Contribution - Published proceedings: Abstract

Vu, H. T. H., Hook, S., & McDowell, A. (2015). Systematic study of the preparation and characterization of rutin polymeric nanoparticles using design of experiments. Proceedings of the Diagnostic Drug Device Discovery (D4) Conference. Retrieved from https://www.regonline.com.au/builder/site/Default.aspx?EventID=1758070

Azhari, H., Tey, W. K., Hook, S., Boyd, B. J., & Rizwan, S. (2015). Interaction of cationic cubosomes with immortalized human brain endothelial cells. Proceedings of the Diagnostic Drug Device Discovery (D4) Conference. Retrieved from https://www.regonline.com.au/builder/site/Default.aspx?EventID=1758070

Cooper, A., Hook, S., Tyndall, J. D. A., & Vernall, A. (2015). Development of fluorescent ligands as tools for studying the cannabinoid type 2 receptor. Proceedings of the Diagnostic Drug Device Discovery (D4) Conference. Retrieved from https://www.regonline.com.au/builder/site/Default.aspx?EventID=1758070

Sanhajariya, S., Matikonda, S. S., Gamble, A. B., & Hook, S. (2015). Evaluation of the cytotoxicity and kinetic profiles of the functionalised p-aminobenzyloxycarbonl (PABC) prodrugs. Proceedings of the Diagnostic Drug Device Discovery (D4) Conference. Retrieved from https://www.regonline.com.au/builder/site/Default.aspx?EventID=1758070

Bobbala, S., Gibson, B., & Hook, S. (2015). Sustained release formulations for vaccine delivery. Proceedings of the Diagnostic Drug Device Discovery (D4) Conference. Retrieved from https://www.regonline.com.au/builder/site/Default.aspx?EventID=1758070

Azhari, H., Boyd, B., Hook, S., & Rizwan, S. (2015). Enhanced uptake of drug into the brain when delivered in BBB-targeted cubosomes. In B. Leitch (Ed.), Proceedings of the 33rd International Australasian Winter Conference on Brain Research. (pp. 46). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr

Hook, S. (2015). Developing platforms for maximising immunisation responses. Proceedings of the Australasian Pharmaceutical Science Association and the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (APSA-ASCEPT) Joint Scientific Meeting: Drugs to Medicines: Up Close and Personal. 208. Retrieved from http://www.asceptasm.com/

Azhari, H., Rizwan, S., Hook, S., Boyd, B. J., & Strauss, M. (2015). Modifying the surface of cubosomes with blood-brain barrier targeting ligands strongly influences its nanostructure. Proceedings of the 27th National Conference on Microscopy. Retrieved from http://microscopy2015.otago.ac.nz/index.html

Conference Contribution - Poster Presentation (not in published proceedings)

Azhari, H., Hook, S., Boyd, B. J., & Rizwan, S. B. (2015, July). Zebrafish can be used to determine permeability of nanoparticles across the blood-brain barrier in vivo. Poster session presented at the 11th International Conference on Cerebral Vascular Biology, Paris, France.

Conference Contribution - Verbal presentation and other Conference outputs

Hook, S. (2015, May). One-shot sustained release nanoparticle vaccines. Verbal presentation at the Fifth International Conference on Modern Vaccines Adjuvants & Delivery Systems, Leiden, The Netherlands.

Hook, S. (2015, April). Development of community pharmacists as independent vaccinators. Verbal presentation at the Health Workforce Research and Policy Symposium: Questions, Conundrums and the Road Ahead, Wellington, New Zealand.

2014

Journal - Research Article

Hubert, M., Larsen, D. S., Hayman, C. M., Rades, T., & Hook, S. (2014). Physical characterization of synthetic phosphatidylinositol dimannosides and analogues in binary systems with phosphatidylcholine. Molecular Pharmaceutics, 11(3), 913-921. doi: 10.1021/mp400588y

Neumann, S., Burkert, K., Kemp, R., Rades, T., Dunbar, P. R., & Hook, S. (2014). Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants. Immunology & Cell Biology, 92, 535-542. doi: 10.1038/icb.2014.21

Even, M.-P., Young, K., Winter, G., Hook, S., & Engert, J. (2014). In vivo investigation of twin-screw extruded lipid implants for vaccine delivery. European Journal of Pharmaceutics & Biopharmaceutics, 87(2), 338-346. doi: 10.1016/j.ejpb.2014.02.014

Rattanapak, T., Birchall, J. C., Young, K., Kubo, A., Fujimori, S., Ishii, M., & Hook, S. (2014). Dynamic visualization of dendritic cell-antigen interactions in the skin following transcutaneous immunization. PLoS ONE, 9(2), e89503. doi: 10.1371/journal.pone.0089503

Conference Contribution - Published proceedings: Abstract

Liau, J. J., Kaneko, K., Hook, S., Prestidge, C., & Barnes, T. (2014). Nanostructured lipid in double emulsion: Multi-compartment system for oral vaccine delivery. Proceedings of the 5th Pharmaceutical Sciences World Congress (PSWC). Retrieved from http://www.fip.org/pswc2014/Melbourne/2041/Programme/

Kaneko, K., McDowell, A., Ishii, Y., Hayman, C., & Hook, S. (2014). A validated LC-MS/MS method for the quantitation of α-GalactosylCeramide incorporation in liposomes. Proceedings of the 5th Pharmaceutical Sciences World Congress (PSWC). Retrieved from http://www.fip.org/pswc2014/Melbourne/2041/Programme/

Bobbala, S., Tamboli, V., Young, K., McDowell, A., Mitra, A. K., & Hook, S. (2014). Novel injectable pentablock copolymer-based thermoresponsive hydrogels for sustained vaccine delivery. Proceedings of the 5th Pharmaceutical Sciences World Congress (PSWC). Retrieved from http://www.fip.org/pswc2014/Melbourne/2041/Programme/

Conference Contribution - Poster Presentation (not in published proceedings)

Lee, A., Gamble, A., & Hook, S. (2014, November). Characterisation of PDMS-b-PDMAEMA micelles. Poster session presented at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.

Shirley, S., Hook, S., Kemp, R., & Neumann, S. (2014, November). MDSC and their potential role in therapeutic vaccine formulations. Poster session presented at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.

Pena, A., Doronin, A., Hook, S., & Meglinski, I. (2014, November). Assessment of molecular diffusion in skin by Optical Coherence Tomography. Poster session presented at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Hook, S. (2014, July). Novel poly lactic-co-glycolic acid (PLGA) loaded-pentablock copolymer thermoresponsive hydrogels for sustained vaccine delivery. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Palmerston North, New Zealand.

Bobbala, S., Tamboli, V., McDowell, A., Mitra, A. K., & Hook, S. (2014, November). Novel injectable pentablock copolymer hydrogels for sustained release cancer vaccines. Verbal presentation at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.

2013

Journal - Research Article

Rattanapak, T., Birchall, J., Young, K., Ishii, M., Meglinski, I., Rades, T., & Hook, S. (2013). Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and two-photon microscopy. Journal of Controlled Release, 172(3), 894-903. doi: 10.1016/j.jconrel.2013.08.018

Scherließ, R., Buske, S., Young, K., Weber, B., Rades, T., & Hook, S. (2013). In vivo evaluation of chitosan as an adjuvant in subcutaneous vaccine formulations. Vaccine, 31(42), 4812-4819. doi: 10.1016/j.vaccine.2013.07.081

Hubert, M., Compton, B. J., Hayman, C. M., Larsen, D. S., Painter, G. F., Rades, T., & Hook, S. (2013). Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues. Molecular Pharmaceutics, 10(5), 1928-1939. doi: 10.1021/mp300707a

Rizwan, S. B., McBurney, W. T., Young, K., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2013). Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses. Journal of Controlled Release, 165(1), 16-21. doi: 10.1016/j.jconrel.2012.10.020

Journal - Research Other

Hook, S., & Windle, J. (2013). Community pharmacy influenza immunisation increases vaccine uptake and gains public approval. Australian & New Zealand Journal of Public Health, 37(5), 489-490. doi: 10.1111/1753-6405.12109

Conference Contribution - Published proceedings: Abstract

Neumann, S., Kemp, R., Dunbar, R., Rades, T., & Hook, S. (2013). Activation of the NLRP3 inflammasome through chitosan nanoparticles and subsequent cytokine production leads to the generation of CD11b⁺ Gr-1⁺ myeloid derived suppressor cells. Proceedings of the 11th Annual Meeting of the Association for Cancer Immunotherapy (CIMT). (pp. 178). Retrieved from http://www.cimt.eu/meetings/archive

Painter, G. F., Tang, C., Anderson, R. J., Compton, B. J., Hayman, C. M., Johnston, K. A., Young, K., Hook, S., Larsen, D. S., & Hermans, I. F. (2013). Synthetic self-adjuvanting peptide vaccines. Proceedings of the New Zealand Institute of Chemistry (NZIC) Conference. Christchurch, New Zealand: NZIC. [Abstract]

Hook, S. (2013). Turning weapons of mass destruction into precision guided munitions. Proceedings of the Australasian Pharmaceutical Science Association (APSA) Conference. Retrieved from http://apsa-online.org/home.html

Neumann, S., Young, K., Kemp, R., Painter, G., Dunbar, R., & Hook, S. (2013). Investigating cytotoxic T cell responses to long peptide vaccine formulations. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 158). Retrieved from http://www.asi2013.org/

Highton, A., Hook, S., & Kemp, R. (2013). Immunisation using a sustained release vaccine generates functional CD8 T cell memory. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 156-157). Retrieved from http://www.asi2013.org/

Subharat, S., Shu, D., Zheng, T., Buddle, B. M., Hook, S., Janssen, P. H., & Wedlock, D. N. (2013). Evaluation of salivary antibody and potential adjuvants for anti-methanogen vaccination in New Zealand sheep. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 143-144). Retrieved from http://www.asi2013.org/

Hook, S. (2013). Making great vaccines even better. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 51). Retrieved from http://www.asi2013.org/

Neumann, S., Kemp, R., Rades, T., Dunbar, R., & Hook, S. (2013). Evaluating adjuvant characteristics of particulate formulations. Proceedings of 15th Conference on Formulation and Delivery of Bioactives: Found in Translation. Retrieved from http://bioactives.otago.ac.nz/

Hook, S. (2013). (Almost) needle-free immunisation: Transcutaneous delivery of peptide actives. Proceedings of 15th Conference on Formulation and Delivery of Bioactives: Found in Translation. Retrieved from http://bioactives.otago.ac.nz/

Conference Contribution - Poster Presentation (not in published proceedings)

Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2013, September). Coated liposomes as oral vaccines for allergies. Poster session presented at the Division of Health Sciences Research Forum: Foundations for Health: Otago Health Research, Christchurch, New Zealand.

Hook, S., Young, K., Hermans, I., & Painter, G. (2013, May). Bridging innate and adaptive immunity through the development of an optimised formulation for the subcutaneous delivery a-galactosylceramide. Poster session presented at the Keystone Symposia on Molecular and Cellular Biology: Innate Immune Response in the Pathogenesis of Infectious Disease, Ouro Preto, Brasil.

Conference Contribution - Verbal presentation and other Conference outputs

Hook, S. (2013, July). Investigation of vaccine adjuvant activity of liposomes containing phophatidylinositol dimannosides and analogues. Verbal presentation at the 40th Annual Meeting & Exposition of the Controlled Release Society (CRS): Emerging Challenges for Global Delivery, Honolulu, Hawaii.

Hook, S. (2013, July). In vivo assessment of melanoma peptide vaccine formulations. Verbal presentation at the 40th Annual Meeting & Exposition of the Controlled Release Society (CRS): Emerging Challenges for Global Delivery, Honolulu, Hawaii.

Other Research Output

Hook, S. (2013, August). Why vaccines are good and how we can make them better. University of Otago, Dunedin, New Zealand. [Inaugural Professorial Lecture].

2012

Journal - Research Article

Rattanapak, T., Young, K., Rades, T., & Hook, S. (2012). Comparative study of liposomes, transfersomes, ethosomes and cubosomes for transcutaneous immunisation: Characterisation and in vitro skin penetration. Journal of Pharmacy & Pharmacology, 64(11), 1560-1569. doi: 10.1111/j.2042-7158.2012.01535.x

Kamali, T., Doronin, A., Rattanapak, T., Hook, S., & Meglinski, I. (2012). Assessment of transcutaneous vaccine delivery by optical coherence tomography. Laser Physics Letters, 9(8), 607-610. doi: 10.7452/lapl.201210046

Gordon, S., Young, K., Wilson, R., Rizwan, S., Kemp, R., Rades, T., & Hook, S. (2012). Chitosan hydrogels containing liposomes and cubosomes as particulate sustained release vaccine delivery systems. Journal of Liposome Research, 22(3), 193-204. doi: 10.3109/08982104.2011.637502

Conference Contribution - Published proceedings: Full paper

Kamali, T., Rattanapak, T., Hook, S., & Meglinski, I. (2012). Application of optical coherence tomography for assessment of transcutaneous vaccine delivery. Proceedings of SPIE (Vol. 8337): Saratov Fall Meeting: Optical Technologies in Biophysics and Medicine XIII. 833706. doi: 10.1117/12.923733

Conference Contribution - Published proceedings: Abstract

Highton, A., Girardin, A., Hook, S., & Kemp, R. (2012). Immunisation using a sustained release vaccine generates CD8 T cell memory population in the gut. New Zealand Medical Journal, 125(1364). Retrieved from http://www.nzma.org.nz/journal

Highton, A., Girardin, A., Hook, S. M., & Kemp, R. A. (2012). Immunisation using sustained release vaccines generates a discrete CD8 T cell memory population in the gut. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/

Neumann, S., Anzer, S., Boyd, B., Rades, T., & Hook, S. (2012). Investigating the phase behaviour of Freund’s incomplete adjuvant: A closer look at Mannide monooleate. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/

Hubert, M., Hook, S., Larsen, D., Hayman, C., Painter, G., & Rades, T. (2012). Investigating the interfacial behaviour of novel PIM Mimetics in pure and mixed monolayers using the Langmuir-trough technique. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/

Shen, W., Mros, S., McConnell, M., Hook, S., & Strachan, C. (2012). Microbiological quality of imported sexual performance medications. New Zealand Medical Journal, 125(1355). Retrieved from http://www.nzma.org.nz/journal

Conference Contribution - Poster Presentation (not in published proceedings)

Highton, A. J., Girardin, A., Hook, S. M., & Kemp, R. A. (2012, September). Immunisation using sustained release vaccines generates a discrete CD8T cell memory population in the gut. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.

Hubert, M., Rades, T., Larsen, D., Hayman, C., Compton, B., & Hook, S. (2012, March). Physicochemical and biological characterization of PIM mimetics, novel immune modulating agents. Poster session presented at the 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey.

Conference Contribution - Verbal presentation and other Conference outputs

Rattanapak, T., Birchall, J., Meglinski, I., Rades, T., & Hook, S. (2012, June). Optimising transcutaneous immunization using microneedles and a colloidal carrier. Verbal presentation at the 39th Annual Meeting & Exposition of the Controlled Release Society: Smart Materials: From Innovation to Translation, Québec City, Canada.

2011

Journal - Research Article

Hook, S. M., Phipps-Green, A. J., Faiz, F., McNoe, L., McKinney, C., Hollis-Moffatt, J. E., & Merriman, T. R. (2011). Smad2: A candidate gene for the murine autoimmune diabetes locus Idd21.1. Journal of Clinical Endocrinology & Metabolism, 96(12), E2072-E2077. doi: 10.1210/jc.2011-0463

Rizwan, S. B., Assmus, D., Boehnke, A., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2011). Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines. European Journal of Pharmaceutics & Biopharmaceutics, 79(1), 15-22. doi: 10.1016/j.ejpb.2010.12.034

Kojarunchitt, T., Hook, S., Rizwan, S., Rades, T., & Baldursdottir, S. (2011). Development and characterisation of modified poloxamer 407 thermoresponsive depot systems containing cubosomes. International Journal of Pharmaceutics, 408(1-2), 20-26. doi: 10.1016/j.ijpharm.2011.01.037

Conference Contribution - Poster Presentation (not in published proceedings)

Kojarunchitt, T., Young, K., Baldursdottir, S., Dong, Y., Boyd, B., Rades, T., & Hook, S. (2011, December). Thermoresponsive gels as sustained release vaccine delivery systems. Poster session presented at the 41st Australasian Society for Immunology (ASI) Annual Meeting, Adelaide, Australia.

Neumann, S., Boyd, B., Rades, T., Hook, S., & Anzer, S. (2011, December). Investigating the phase behaviour of Freund's incomplete adjuvant: A closer look on Mannide monooleate. Poster session presented at the 41st Australasian Society for Immunology (ASI) Annual Meeting, Adelaide, Australia.

Highton, A. J., Girardin, A., Hook, S. M., & Kemp, R. A. (2011, December). Immunisation using sustained release vaccines generates a discrete CD8 T cell memory population in the gut. Poster session presented at the 41st Australasian Society for Immunology (ASI) Annual Meeting, Adelaide, Australia.

Hubert, M., Hook, S., Larsen, D., Hayman, C., Painter, G., Rendle, P., & Rades, T. (2011, October). Investigating the interfacial behavior of novel PIM mimetics in pure and mixed monolayers using the Langmuir-trough technique. Poster session presented at the American Association of Pharmaceutical Sciences (AAPS) Annual Meeting and Exposition, Washington, D.C.

Rattanapak, T., Young, K., Rades, T., & Hook, S. (2011, October). Transcutaneous immunisation using lipid colloidal systems. Poster session presented at the American Association of Pharmaceutical Sciences (AAPS) Annual Meeting and Exposition, Washington, D.C.

Conference Contribution - Verbal presentation and other Conference outputs

Kojarunchitt, T., Baldursdottir, S., Boyd, B., Rades, T., & Hook, S. (2011, December). Thermoresponsive gels as sustained release vaccine delivery systems. Verbal presentation at the Australasian Pharmaceutical Science Association (APSA) Annual Conference: Science Informing Practice: Practice Informing Science, Adelaide, Australia.

Hubert, M., Hook, S., Larsen, D., Hayman, C., Painter, G., Rendle, P., & Rades, T. (2011, February). Monolayer study of PIM mimetics: Novel immunomodulating agents. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Rattanapak, T., Young, K., Rades, T., & Hook, S. (2011, February). Transcutaneous immunisation by lipid colloidal systems. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Kojarunchitt, T., Baldursdottir, S., Rizwan, S., Rades, T., & Hook, S. (2011, February). In vivo investigation of modified P407 gels containing cubosomes as vaccine delivery system. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

2010

Journal - Research Article

Rizwan, S. B., Boyd, B. J., Rades, T., & Hook, S. (2010). Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins. Expert Opinion on Drug Delivery, 7(10), 1133-1144. doi: 10.1517/17425247.2010.515584

Gordon, S., Teichmann, E., Young, K., Finnie, K., Rades, T., & Hook, S. (2010). In vitro and in vivo investigation of thermosensitive chitosan hydrogels containing silica nanoparticles for vaccine delivery. European Journal of Pharmaceutical Sciences, 41(2), 360-368. doi: 10.1016/j.ejps.2010.07.004

Conference Contribution - Published proceedings: Full paper

Singh, R., Hook, S., Rades, T., & Graf, A. (2010). Influence of viscosity on entrapment and in vitro release of FITC-Ova from poly(alkylcyanoacrylate) nanoparticles dispersed in self-gelling microemulsion templates. 37th Annual Meeting & Exposition of the Controlled Release Society. Retrieved from http://www.controlledrelease.org/meeting/2010/program/ProgramBook.cfm

Conference Contribution - Published proceedings: Abstract

Kojarunchitt, T., Hook, S., Rizwan, S., Rades, T., & Baldursdottir, S. (2010). Development of sustained release vaccine delivery system containing modified poloxamer 407 loaded with cubosomes. Proceedings of the Globalization of Pharmaceutics Education Network (GPEN) 8th Biennial Meeting. (pp. 139). Retrieved from http://www.pharmacy.unc.edu/news/events/globalization-of-pharmaceutics-education-network-eighth-meeting-2010/program/GPEN2010_Program.pdf

Highton, A., Girardin, A., Hook, S., & Kemp, R. (2010). Site-specific memory T cells generated from sustained antigen-release vaccination. New Zealand Medical Journal. 123(1327). Retrieved from http://journal.nzma.org.nz/journal/123-1327/4493/content.pdf

Singh, R., Hook, S., Graf, A., & Rades, T. (2010). Polymeric nanoparticles dispersed in self-gelling microemulsion templates for sustained vaccine delivery. In L. Emmerton, A. Peters, D. Ross & B. Ross (Eds.), Proceedings of the Australasian Pharmaceutical Science Association (APSA) Annual Conference: Focus on the Future: Research and Education for a Healthier Community. (pp. 124). APSA. [Abstract]

Hubert, M., Hook, S., Larsen, D., Hayman, C., Painter, G., Rendle, P., & Rades, T. (2010). Synthesis and physical characterisation of PIM mimetics as novel immunomodulating agents. In L. Emmerton, A. Peters, D. Ross & B. Ross (Eds.), Proceedings of the Australasian Pharmaceutical Science Association (APSA) Annual Conference: Focus on the Future: Research and Education for a Healthier Community. (pp. 33). APSA. [Abstract]

Rattanapak, T., Rades, T., & Hook, S. (2010). Quantitation of entrapped MPL and Quil A in lipid transcutaneous vaccines using high performance liquid chromatography and evaporate light scattering detection. In L. Emmerton, A. Peters, D. Ross & B. Ross (Eds.), Proceedings of the Australasian Pharmaceutical Science Association (APSA) Annual Conference: Focus on the Future: Research and Education for a Healthier Community. (pp. 108). APSA. [Abstract]

Rattanapak, T., Rades, T., & Hook, S. (2010). Transcutaneous immunisation using colloidal carriers. Journal of Pharmacy & Pharmacology, 62(10), (pp. 1312-1313). doi: 10.1111/j.2042-7158.2010.01178.x

Conference Contribution - Poster Presentation (not in published proceedings)

Singh, R., Hook, S., Graf, A., & Rades, T. (2010, September). The effect of viscosity on entrapment and in vitro release of FITC-OVA from self-gelling microemulsion templates. Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand.

Hubert, M., Hook, S., Rades, T., Hayman, C., Painter, G., Rendle, P., & Larsen, D. (2010, February). Formulation and immunological characterization of novel carbohydrate containing immunopharmaceuticals. Poster session presented at the New Zealand Chapter of the Controlled Release Society 12th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Rattanapak, T., Rades, T., & Hook, S. (2010, February). Transcutaneous delivery of peptide vaccines using lipid carriers (liposomes, transfersomes, ethosomes and cubosomes). Poster session presented at the New Zealand Chapter of the Controlled Release Society 12th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Girardin, A., Hook, S. M., Kemp, R. A., & Highton, A. J. (2010, July). Site specific memory T cells generated from slow antigen release vaccination. Verbal presentation at the New Zealand Australasian Society for Immunology (NZ ASI) Branch Meeting, Wellington, New Zealand.

Singh, R., Hook, S., Rades, T., & Graf, A. (2010, February). Influence of composition variables of in situ gelling microemulsion templates on viscosity and release of FITC-Ova containing polymeric nanoparticles for sustained protein delivery. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 12th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

2009

Journal - Research Article

Ferderber, K., Hook, S., & Rades, T. (2009). Phosphatidyl choline-based colloidal systems for dermal and transdermal drug delivery. Journal of Liposome Research, 19(4), 267-277. doi: 10.3109/08982100902814006

Daines, A. M., Greatrex, B. W., Hayman, C. M., Hook, S. M., McBurney, W. T., Rades, T., … Sims, I. M. (2009). Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems. Bioorganic & Medicinal Chemistry, 17(14), 5207-5218. doi: 10.1016/j.bmc.2009.05.043

Myschik, J., Rades, T., & Hook, S. (2009). Advances in lipid-based subunit vaccine formulations. Current Immunology Reviews, 5(1), 42-48.

Rizwan, S. B., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2009). Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: Characterisation, swelling and release kinetics. Journal of Pharmaceutical Sciences, 98(11), 4191-4204. doi: 10.1002/jps.21724

Greatrex, B. W., Brodie, S. J., Furneaux, R. H., Hook, S. M., McBurney, W. T., Painter, G. F., Rades, T., & Rendle, P. M. (2009). The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers. Tetrahedron, 65(15), 2939-2950. doi: 10.1016/j.tet.2009.02.018

Braund, R., Hook, S. M., Greenhill, N., & Medlicott, N. J. (2009). Distribution of fibroblast growth factor-2 (FGF-2) within model excisional wounds following topical application. Journal of Pharmacy & Pharmacology, 61(2), 193-200. doi: 10.1211/jpp/61.02.0008

Graf, A., Rades, T., & Hook, S. M. (2009). Oral insulin delivery using nanoparticles based on microemulsions with different structure-types: Optimisation and in vivo evaluation. European Journal of Pharmaceutical Sciences, 37(1), 53-61. doi: 10.1016/j.ejps.2008.12.017

Conference Contribution - Published proceedings: Full paper

Gordon, S., McBurney, W. T., Wilson, R., Rades, T., & Hook, S. (2009). In vitro and in vivo investigation of chitosan hydrogels containing liposomes as vaccine delivery systems. Proceedings of the 36th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] St. Paul, MN: CRS. [Full Paper]

Ferderber, K., Rades, T., & Hook, S. (2009). Phosphatidylcholine based colloidal systems for transdermal and dermal delivery of peptides. Proceedings of the 36th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] St. Paul, MN: CRS. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Kojarunchitt, T., Baldursdottir, S., Rades, T., & Hook, S. (2009). Development of vaccine formulations containing particulates in thermoresponsive gels. In S. Aldous, G. Peterson, G. Jacobson & L. Bereznicki (Eds.), Proceedings of the Australasian Pharmaceutical Science Association (APSA) Annual Conference in conjunction with the Australian Controlled Release Society (Aus-CRS) Symposium. (pp. 112). APSA. [Abstract]

Singh, R., Hook, S., Rades, T., & Graf, A. (2009). Influence of viscosity of in situ gelling microemulsion templates on entrapment and release of FITC-Ova containing poly(alkylcyanoacrylate) nanoparticles. In S. Aldous, G. Peterson, G. Jacobson & L. Bereznicki (Eds.), Proceedings of the Australasian Pharmaceutical Science Association (APSA) Annual Conference in conjunction with the Australian Controlled Release Society (Aus-CRS) Symposium. (pp. 69). APSA. [Abstract]

Gordon, S., Rades, T., & Hook, S. (2009). In-vitro and in-vivo investigation of thermosensitive chitosan hydrogels containing liposomes or silica nanoparticles for vaccine delivery. Journal of Pharmacy & Pharmacology, 61(Suppl. 1), (pp. A45). doi: 10.1211/002235709789036991

Hook, S., Myschik, J., Gordon, S., Rizwan, S., McBurney, W., & Rades, T. (2009). Designing sustained release, particulate, sub-unit vaccines. Proceedings of the Webster Centre for Infectious Diseases Symposium. WCID. Retrieved from http://www.webstercentre.otago.ac.nz/WCIDSymposiumProgramme.pdf

Conference Contribution - Poster Presentation (not in published proceedings)

Ferderber, K., Rades, T., & Hook, S. (2009, July). Phosphatidylcholine based colloidal systems for transdermal and dermal delivery of peptides. Poster session presented at the 36th Annual Meeting & Exposition of the Controlled Release Society, Copenhagen, Denmark.

Conference Contribution - Verbal presentation and other Conference outputs

Hook, S. (2009, November). Pharmacist immunisers: A feasible concept? Verbal presentation at the National Immunisation Conference, Auckland, New Zealand.

Hook, S. (2009, November). New Zealand preclinical developments: Formulation of safe, immune stimulatory vaccines. Verbal presentation at the National Immunisation Conference, Auckland, New Zealand.

Gordon, S., McBurney, W., Wilson, R., Rades, T., & Hook, S. (2009, July). In vitro and in vivo investigation of chitosan hydrogels containing liposomes as vaccine delivery systems. Verbal presentation at the 36th Annual Meeting & Exposition of the Controlled Release Society, Copenhagen, Denmark.

Gordon, S., McBurney, W. T., Wilson, R., Rades, T., & Hook, S. (2009, June). Investigation of thermosensitive chitosan hydrogels containing antigen-loaded nanoparticles for vaccine delivery. Verbal presentation at the New Zealand Australasian Society for Immunology (NZ ASI) Branch Meeting, Wellington, New Zealand.

Singh, R., Hook, S., Rades, T., & Graf, A. (2009, February). In situ forming liquid crystalline systems on the basis of microemulsions for sustained drug delivery. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 11th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Merriman, T., McNoe, L., Phipps-Green, M., Hollis-Moffatt, J., Hook, S., & Faiz, F. (2009, July). The SMAD2 gene, the IDD21.1 locus and autoimmune diabetes in the non-obese diabetic mouse. Verbal presentation at the 33rd New Zealand Society for the Study of Diabetes Annual Scientific Meeting, Dunedin, New Zealand.

2008

Journal - Research Article

Graf, A., Jack, K. S., Whittaker, A. K., Hook, S. M., & Rades, T. (2008). Protein delivery using nanoparticles based on microemulsions with different structure-types. European Journal of Pharmaceutical Sciences, 33, 434-444.

McBurney, W. T., Lendemans, D. G., Myschik, J., Hennessy, T., Rades, T., & Hook, S. (2008). In vivo activity of cationic immune stimulating complexes (PLUSCOMs). Vaccine, 26, 4549-4556. doi: 10.1016/j.vaccine.2008.06.024

Myschik, J., McBurney, W. T., Rades, T., & Hook, S. (2008). Immunostimulatory lipid implants containing Quil-A and DC-cholesterol. International Journal of Pharmaceutics, 363, 91-98. doi: 10.1016/j.ijpharm.2008.07.014

Myschik, J., McBurney, W. T., Hennessy, T., Rades, T., & Hook, S. (2008). Immunogenicity of lipid sustained release implants containing imiquimod, α-galactosylceramide, or Quil-A. Pharmazie, 63(9), 686-692. doi: 10.1691/ph.2008.8072

Myschik, J., McBurney, W. T., Hennessy, T., Phipps-Green, A., Rades, T., & Hook, S. (2008). Immunostimulatory biodegradable implants containing the adjuvant Quil-A - Part II: In vivo evaluation. Journal of Drug Targeting, 16(3), 224-232. doi: 10.1080/10611860701848886

Myschik, J., Eberhardt, F., Rades, T., & Hook, S. (2008). Immunostimulatory biodegradable implants containing the adjuvant Quil-A - Part I: Physicochemical characterisation. Journal of Drug Targeting, 16(3), 213-223. doi: 10.1080/10611860701848860

Graf, A., Ablinger, E., Peters, S., Zimmer, A., Hook, S., & Rades, T. (2008). Microemulsions containing lecithin and sugar-based surfactants: Nanoparticle templates for delivery of proteins and peptides. International Journal of Pharmaceutics, 350, 351-360. doi: 10.1016/j.ijpharm.2007.08.053

Gordon, S., Saupe, A., McBurney, W., Rades, T., & Hook, S. (2008). Comparison of chitosan nanoparticles and chitosan hydrogels for vaccine delivery. Journal of Pharmacy & Pharmacology, 60, 1591-1600. doi: 10.1211/jpp/60.12.0004

Conference Contribution - Published proceedings: Full paper

Rizwan, S. B., McBurney, W., Boyd, B. J., Rades, T., & Hook, S. (2008). In vitro activity of phytantriol cubosomes containing the adjuvants imiquimod or monophosphoryl lipid A in bone marrow derived dendritic cells. Proceedings of the 35th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] St Paul, MN: CRS. [Full Paper]

Krauel-Goellner, K., Girvan, L., Hook, S., & Rades, T. (2008). Characterisation of colloidal drug delivery systems: From the naked eye to cryo-FESEM. Proceedings of the 6th World Meeting on Pharmaceutics, Bioparmaceutics and Pharmaceutical Technology. [CD-ROM] [Full Paper]

Graf, A., Jack, K., Whittaker, A., Hook, S., & Rades, T. (2008). Microemulsion-based nanoparticles loaded with insulin. Proceedings of the 35th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] St Paul, MN: CRS. [Full Paper]

Rizwan, S. B., Boyd, B. J., Rades, T., & Hook, S. (2008). Characterisation, swelling and release from liquid crystalline systems of phytantriol and glycerylmonooleate as platforms for controlled release of bioactives. Proceedings of the 35th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] St Paul, MN: CRS. [Full Paper]

Gordon, S., Saupe, A., McBurney, W. T., Hennessy, T., Rades, T., & Hook, S. (2008). In vivo investigation of a thermosensitive chitosan hydrogel as a sustained release vaccine delivery system. Proceedings of the 35th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] St Paul, MN: CRS. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Faiz, F., McNoe, L., Phipps-Green, M., Hollis-Moffatt, J., Hook, S., & Merriman, T. (2008). The Smad2 gene, the Idd21.1 locus and autoimmune diabetes in the non-obese diabetic mouse. Proceedings of the 8th Annual Australasian Microarray and Associated Technologies (AMATA) Conference. Retrieved from http://www.amata.org.au/index.php/resources/2008-conference-abstracts

Gordon, S., Saupe, A., McBurney, W., Hennessy, T., Rades, T., & Hook, S. (2008). Thermosensitive chitosan hydrogels as potential sustained release vaccine delivery systems. New Zealand Medical Journal, 121(1278). Retrieved from http://journal.nzma.org.nz/journal/121-1278/3179/content.pdf

Graf, A., Rades, T., & Hook, S. M. (2008). Bioactivity of insulin-loaded nanoparticles dispersed in biocompatible microemulsions. AAPS Journal, 10(S2). Retrieved from http://www.aapsj.org/abstracts/AM_2008/AAPS2008-001821.PDF

Rizwan, S., McBurney, W., Boyd, B., Rades, T., & Hook, S. (2008). Enhanced type-1 immune response from a novel particulate vaccine delivery system comprised of phytantriol cubosomes containing toll-like receptor agonists imiquimod and or monophosphoryl lipid A. AAPS Journal, 10(S2). Retrieved from http://www.aapsj.org/abstracts/AM_2008/AAPS2008-001145.PDF

Ferderber, K., Hook, S., & Rades, T. (2008). Lecithin based particulate systems for dermal/transdermal drug delivery. AAPS Journal, 10(S2). Retrieved from http://www.aapsj.org/abstracts/AM_2008/AAPS2008-001147.PDF

Conference Contribution - Poster Presentation (not in published proceedings)

Daines, A. M., Greatrex, B. W., Hayman, C. M., Hook, S., McBurney, W., Rades, T., … Sims, I. (2008, November-December). Mannosylated saponins based on oleanolic and glycyrrhizic acids. Poster session presented at the New Zealand Institute of Chemistry, New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Biologists Combined Conference, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Braund, R., Hook, S. M., Greenhill, N. S., & Medlicott, N. J. (2008, February). Confocal microscopy to determine intra-wound distribution of FGF-2 following topical application. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 10th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Rizwan, S. B., McBurney, W., Boyd, B. J., Rades, T., & Hook, S. (2008, November). In-vivo activity of a novel particulate vaccine delivery system comprised of phytantriol cubosomes containing toll-like receptor agonists imiquimod and monophosphoryl lipid A. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.

Gordon, S., Saupe, A., McBurney, W., Hennessy, T., Rades, T., & Hook, S. (2008, November). In-vivo immunogenicity of sustained release, thermosensitive chitosan hydrogel systems. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.

Myschik, J., McBurney, W., Rades, T., & Hook, S. (2008, November). Formulation and delivery of immunogenic sustained release subunit vaccines. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.

Rades, T., & Hook, S. (2008, February). Nanoparticles as delivery systems for subunit vaccines: A pharmaceutical approach. Invited presentation at the 1st International Conference on Drug Design and Discovery, Dubai, United Arab Emirates.

2007

Journal - Research Article

Braund, R., Hook, S., & Medlicott, N. J. (2007). The role of topical growth factors in chronic wounds. Current Drug Delivery, 4(3), 195-204. doi: 10.2174/156720107781023857

Demana, P. H., Davies, N. M., Hook, S., & Rades, T. (2007). Analysis of Quil A-phospholipid mixtures using drift spectroscopy. International Journal of Pharmaceutics, 342, 49-61.

Boyd, B. J., Rizwan, S. B., Dong, Y.-D., Hook, S., & Rades, T. (2007). Self-assembled geometric liquid-crystalline nanoparticles imaged in three dimensions: Hexosomes are not necessarily flat hexagonal prisms. Langmuir, 23(25), 12461-12464. doi: 10.1021/la7029714

Rizwan, S. B., Dong, Y.-D., Boyd, B. J., Rades, T., & Hook, S. (2007). Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM). Micron, 38, 478-485. doi: 10.1016/j.micron.2006.08.003

Krauel, K., Girvan, L., Hook, S., & Rades, T. (2007). Characterisation of colloidal drug delivery systems from the naked eye to Cryo-FESEM. Micron, 38, 796-803.

Lendemans, D. G., Egert, A. M., Hook, S., & Rades, T. (2007). Cage-like complexes formed by DOTAP, Quil-A and cholesterol. International Journal of Pharmaceutics, 332, 192-195.

Conference Contribution - Published proceedings: Full paper

Graf, A., Ablinger, E., Peters, S., Zimmer, A., Hook, S., & Rades, T. (2007). In-situ gelling microemulsions containing lecithin and capryl-caprylyl glucoside as nanoparticle templates: Protein delivery systems with depot effect? Proceedings of the 34th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

Myschik, J., McBurney, W. T., Hennessy, T., Rades, T., & Hook, S. (2007). Comparison of immunogenicity of sustained release implants containing imiquimod, α-galactosylceramide or Quil-A. Proceedings of the 34th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

McBurney, W., Lendemans, D., Hennessy, T., Myschik, J., Rades, T., & Hook, S. (2007). in vivo activity of cationic immune stimulating complexes (PLUSCOMs). Proceedings of the 34th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

Myschik, J., McBurney, W. T., Hennessy, T., Eberhardt, F., Phipps-Green, A., Rades, T., & Hook, S. (2007). In vitro and in vivo investigation of Quil-A containing biodegradable immunostimulatory implants. Proceedings of the 34th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

Hook, S., Rizwan, S., Gordon, S., Saupe, A., & Rades, T. (2007). Towards the development of controlled release cancer vaccines. Proceedings of the 34th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

Graf, A., Ablinger, E., Peters, S., Zimmer, A., Hook, S., & Rades, T. (2007). Nanoparticles for protein delivery from microemulsions containing lecithin and decyl glucoside. Proceedings of the 34th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

Graf, A., Jack, K., Graf, M., Whittaker, A., Hook, S., & Rades, T. (2007). Nanoparticles from different structure-types of microemulsions for protein delivery. Proceedings of the 34th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Radunskaya, A., & Hook, S. (2007). Heuristic optimization of a mathematical model of the innate immune response to cancer vaccines. In A. Korytowski, W. Mitkowski & M. Szymkat (Eds.), Proceedings of the 23rd International Federation for Information Processing 7th Technical Committee Conference. (pp. 237-238). Kraków, Poland: Wydawnictwa Wydzialu Elektrotechniki, Automatyki, Informatyki i Elektroniki. [Abstract]

Rades, T., & Hook, S. (2007). Nanoparticulate systems for the delivery of subunit vaccines. Journal of Pharmacy & Pharmacology, 59(Suppl. 1), (pp. A-67). doi: 10.1211/002235707781850023

Braund, R., Medlicott, N., & Hook, S. (2007). Distribution of fibroblast growth factor-2 within excisional wounds following topical application in rats. New Zealand Medical Journal, 120(1262). Retrieved from http://journal.nzma.org.nz/journal/120-1262/2740/content.pdf

Conference Contribution - Poster Presentation (not in published proceedings)

Rades, T., Hennessy, T., Gavin, P., Ogru, E., & Hook, S. (2007, November). Formulation and characterisation of vesicle dispersions of tocopheryl phosphate and di-tocopheryl phosphate. Poster session presented at the American Association of Pharmaceutical Scientists Annual Meeting and Exposition, San Diego, CA.

Rizwan, S., Assmus, D., Boyd, B., Rades, T., & Hook, S. (2007, November). Spontaneous formation of phytantriol based lyotropic liquid crystalline nanoparticles produced from liquid precursors. Poster session presented at the American Association of Pharmaceutical Scientists Annual Meeting and Exposition, San Diego, CA.

Braund, R., Hook, S., Greenhill, N., & Medlicott, N. (2007, July). Distribution of FGF-2 within excisional wounds following topical application. Poster session presented at the 34th Annual Meeting & Exposition of the Controlled Release Society, Long Beach, CA. Retrieved from http://www.nzma.org.nz/journal/120-1262/2740/content.pdf

Radunskaya, A., & Hook, S. (2007, July-August). Heuristic optimization of a delay-differential model of the immune response to cancer vaccines. Poster session presented at the First Joint International Meeting, Warszawa, Poland.

Rizwan, S., Assmus, D., Boyd, B. J., Rades, T., & Hook, S. (2007, February). Development and characterisation of phytantriol based lyotropic liquid crystalline nanoparticles produced via low viscosity precursors. Poster session presented at the 9th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Rizwan, S., Dong, C., Boyd, B. J., Rades, T., & Hook, S. (2007, February). Characterising bicontinuous cubic nanoparticles by cryo field emission scanning electron microscopy. Poster session presented at the 9th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Graf, A., Albinger, E., Hook, S., & Rades, T. (2007, February). Nanoparticles in a self-gelling microemulsion template. Poster session presented at the 9th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Myschik, J., McBurney, W. T., Hennessy, T., Eberhardt, F., Phipps-Green, A., Rades, T., & Hook, S. (2007, February). Investigation of biodegradable sustained release implants containing the adjuvant Quil-A for the delivery of subunit vaccines. Verbal presentation at the 9th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Graf, A., Jack, K., Graf, M., Whittaker, A., Hook, S., & Rades, T. (2007, February). Nanoparticles from different structure-types of microemulsions for the encapsulation of peptides. Verbal presentation at the 9th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

Hook, S., & Rades, T. (2007, February). Colloidal delivery systems for subunit vaccine delivery: A pharmaceutical approach Part 1: Physico-chemical characterisation. Verbal presentation at the Australian Colloid and Interface Symposium, Sydney, Australia.

Hook, S., & Rades, T. (2007, February). Colloidal delivery systems for subunit vaccine delivery: A pharmaceutical approach Part 2: Immunological testing. Verbal presentation at the Australian Colloid and Interface Symposium, Sydney, Australia.

2006

Journal - Research Article

Krauel, K., Graf, A., Hook, S. M., Davies, N. M., & Rades, T. (2006). Preparation of poly (alkylcyanoacrylate) nanoparticles by polymerization of water-free microemulsions. Journal of Microencapsulation, 23(5), 499-512.

Weir, C., McNeill, A., Hook, S., Harvie, M., La Flamme, A. C., Le Gros, G., & Bäckström, B. T. (2006). Critical role of preproenkephalin in experimental autoimmune encephalomyelitis. Journal of Neuroimmunology, 179, 18-25.

Grimwood, K., Huang, Q. S., Cohet, C., Gosling, I. A., Hook, S. M., Teele, D. W., … Leadbitter, P., & Lennon, D. R. (2006). Rotavirus hospitalisation in New Zealand children under 3 years of age. Journal of Paediatrics & Child Health, 42(4), 196-203. doi: 10.1111/j.1440-1754.2006.00829.x

Saupe, A., McBurney, W., Rades, T., & Hook, S. (2006). Immunostimulatory colloidal delivery systems for cancer vaccines. Expert Opinion on Drug Delivery, 3(3), 345-354.

White, K. L., Rades, T., Furneaux, R. H., Tyler, P. C., & Hook, S. (2006). Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells. Journal of Pharmacy & Pharmacology, 58, 729-737.

White, K., Rades, T., Kearns, P., Toth, I., & Hook, S. (2006). Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research, 23(7), 1473-1481.

Lendemans, D. G., Egert, A. M., Myschik, J., Hook, S., & Rades, T. (2006). On the dilution behaviour of immuno-stimulating complexes (ISCOMs). Pharmazie, 61(8), 689-695.

Myschik, J., Lendemans, D. G., McBurney, W. T., Demana, P. H., Hook, S., & Rades, T. (2006). On the preparation, microscopic investigation and application of ISCOMs. Micron, 37, 724-734.

Conference Contribution - Published proceedings: Full paper

Saupe, A., McBurney, W., Hennessy, T., Rades, T., & Hook, S. (2006). Preparation of immune stimulatory delivery systems using poly(acylcyanoacrylate) and chitosan. Proceedings of the 33rd Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

Saupe, A., McBurney, W., Hennessy, T., Rades, T., & Hook, S. (2006). Preparation of a thermosensitive hydrogel containing chitosan nanoparticles for vaccine delivery. Proceedings of the 33rd Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

Ferderber, K., Hook, S., Becket, G., & Rades, T. (2006). Lecithin based microemulsion systems for transdermal and dermal drug delivery. Proceedings of the 33rd Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Rades, T., & Hook, S. (2006). A pharmaceutical approach to colloidal vaccine delivery. Proceedings of the Immunet Researching for Health Meeting. Retrieved from http://immunet.otago.ac.nz/whatson2.htm

Myschik, J., McBurney, W. T., Eberhardt, F., Hennessy, T., Phipps-Green, M., Rades, T., & Hook, S. (2006). Preparation and investigation of solid lipid implants for sustained release of model antigen. Proceedings of the Immunet Researching for Health Meeting. Retrieved from http://immunet.otago.ac.nz/whatson2.htm

Saupe, A., McBurney, W., Hennessy, T., Rades, T., & Hook, S. (2006). Chitosan as an injectable thermosensitive hydrogel for sustained vaccine delivery. Proceedings of the Immunet Researching for Health Meeting. Retrieved from http://immunet.otago.ac.nz/whatson2.htm

Hook, S., McBurney, W. T., Lendemans, D., & Rades, T. (2006). The immunostimulatory effect of cationic iscoms in a mouse model. Proceedings of the 36th Annual Australasian Society for Immunology Conference. New Zealand: University of Auckland. Retrieved from http://www.nature.com/icb/asi_abs/index.html

Myschik, J., McBurney, W. T., Eberhardt, F., Hennessy, T., Phipps-Green, A., Rades, T., & Hook, S. (2006). Investigation of immune responses stimulated by a sustained release lipidic implant releasing self-assembling colloidal particles. In A. Davey (Ed.), Proceedings of the Australasian Pharmaceutical Science Association Annual Conference. (pp. 38). Adelaide, Australia: APSA. [Abstract]

Rades, T., & Hook, S. (2006). Creating a structured environment for postgraduate studies. In R. Spronken-Smith (Ed.), Spotlight on Teaching at Otago Conference. (pp. 16). Dunedin, New Zealand: HEDC, University of Otago. [Abstract]

Graf, A., Ablinger, E., Hook, S., & Rades, T. (2006). Nanoparticles in a self-gelling microemulsion-template. In A. Davey (Ed.), Proceedings of the Australasian Pharmaceutical Science Association Annual Conference. (pp. 100). Adelaide, Australia: APSA. [Abstract]

Graf, A., Graf, M., Hook, S., & Rades, T. (2006). Poly(alkyl cyanoacrylate) nanoparticles from different structure-types of microemulsions for encapsulation of insulin. In A. Davey (Ed.), Proceedings of the Australasian Pharmaceutical Science Association Annual Conference. (pp. 47). Adelaide, Australia: APSA. [Abstract]

Myschik, J., McBurney, W. T., Eberhardt, F., Hennessy, T., Phipps-Green, M., Rades, T., & Hook, S. (2006). Quil-A containing lipid implants as a potential delivery system for subunit cancer vaccines. New Zealand Medical Journal, 119(1237). Retrieved from http://journal.nzma.org.nz/journal/119-1237/2062/content.pdf

Rizwan, S., Boyd, B., Hook, S., & Rades, T. (2006). Characterisation of bicontinuous cubic liquid crystalline phases by cryo FESEM. In P. Munroe (Ed.), Proceedings of the Australian Conference on Microscopy and Microanalysis. Melbourne, Australia: Australian Microscopy and Microanalysis Society Inc. Retrieved from www.acmm19.org.au

Conference Contribution - Poster Presentation (not in published proceedings)

Lendemans, D. G., Egert, A. M., Hook, S., & Rades, T. (2006, March). Characterisation of dispersions containing Quillaja saponins and cationic lipids. Poster session presented at the 5th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva, Switzerland.

Hook, S., Myschik, J., Lendemans, D., McBurney, W., & Rades, T. (2006, May-June). Pharmaceutical approaches to improving subunit vaccine formulations. Poster session presented at the 1st Australian Vaccines & Immunotherapeutics Development Meeting, Parkville, Australia.

Hook, S., Lendemans, D., Hennessey, T., McBurney, W., & Rades, T. (2006, May). Nanoparticulate vaccine formulations. Poster session presented at the Particles International Conference, Orlando, Florida.

Rizwan, S., Dong, C., Boyd, B., Hook, S., & Rades, T. (2006, May). Characterising bicontinuous cubic nanoparticles by cryo field emission scanning electron microscopy. Poster session presented at the Particles International Conference, Orlando, Florida.

Krauel, K., Rades, T., & Hook, S. (2006, March). Delivery of antigen incorporated into PACA-Quil A nanoparticles to dendritic cells. Poster session presented at the 5th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva, Switzerland.

Braund, R., Hook, S. M., & Medlicott, N. J. (2006, July). Protein release from hydroxypropylmethylcellulose (HPMC) films. Poster session presented at the 33rd Annual Meeting & Exposition of the Controlled Release Society, Vienna, Austria.

Conference Contribution - Verbal presentation and other Conference outputs

Hook, S. (2006, July). Vaccines and immunisation. Verbal presentation at the Pharmacy School Seminar Series, Dunedin, New Zealand.

Braund, R., Hook, S. M., & Medlicott, N. J. (2006, February). Protein release from hydroxypropylmethylcellulose (HPMC) films. Verbal presentation at the 8th Conference on Formulation & Delivery of Bioactives in Association with the New Zealand Chapter Controlled Release Society, Dunedin, New Zealand.

2005

Journal - Research Article

Hollis-Moffatt, J. E., Hook, S. M., & Merriman, T. R. (2005). Colocalization of mouse autoimmune diabetes loci Idd21.1 and Idd21.2 with IddM6 (Human) and Iddm3 (Rat) [Brief Genetics Report]. Diabetes, 54, 2820-2825.

Hook, S., Chan, L., Cutfield, H., Dean, R., Keir, A., Gordon, G., & Norris, P. (2005). Immunisation knowledge and beliefs of health science and non-health science students at the University of Otago. New Zealand Family Physician, 32(6), 394-398.

Chen, Y. E., Beasley, S., Grimwood, K., and the New Zealand Rotavirus Study Group, including Hook, S. (2005). Intussusception and rotavirus associated hospitalisation in New Zealand. Archives of Disease in Childhood, 90, 1077-1081. doi: 10.1136/adc.2005.074104

Armstrong, D. S., Hook, S. M., Jamsen, K. M., Nixon, G. M., Carzino, R., Carlin, J. B., … Grimwood, K. (2005). Lower airway inflammation in infants with cystic fibrosis detected by newborn screening. Pediatric Pulmonology, 40, 500-510.

Krauel, K., Davies, N. M., Hook, S., & Rades, T. (2005). Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerization. Journal of Controlled Release, 106(1-2), 76-87. doi: 10.1016/j.jconrel.2005.04.013

Lendemans, D. G., Myschik, J., Hook, S., & Rades, T. (2005). Cationic cage-like complexes formed by DC-cholestrol, Quil-A, and phospholipid. Journal of Pharmaceutical Sciences, 94(8), 1794-1807.

Demana, P. H., Davies, N. M., Hook, S., & Rades, T. (2005). Quil A-lipid powder formulations releasing ISCOMs and related colloidal stuctures upon hydration. Journal of Controlled Release, 103, 45-59.

Lendemans, D. G., Myschik, J., Hook, S., & Rades, T. (2005). Immuno-stimulating complexes prepared by ethanol injection. Journal of Pharmacy & Pharmacology, 57, 729-733.

Conference Contribution - Published proceedings: Full paper

Lendemans, D. G., Myschik, J., Hook, S., & Rades, T. (2005). Formation of cationic cage-like complexes composed of DC-cholesterol, Quil-A and phospholipid. Proceedings of the 32nd Annual Meeting and Exposition of the Controlled Release Society. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Hennessy, T. M., Schrage, B., McBurney, W. T., Rades, T., Fraser, J., & Hook, S. (2005). Liposomal incorporation of mutated superantigens. Tissue Antigens: Immune Response Genetics. 66(5), (pp. 441). [Abstract]

Lendemans, D., McBurney, W., Hennessy, T. M., Rades, T., & Hook, S. (2005). Delivery of subunit vaccines by cationic formulations containing Quillaja saponins: A comparison with classical iscoms. Tissue Antigens: Immune Response Genetics. 66(5), (pp. 445). [Abstract]

McBurney, W., Thomas, N., Rades, T., & Hook, S. (2005). Development of a vaccine delivery system using imiquimod modified liposomes. Tissue Antigens: Immune Response Genetics. 66(5), (pp. 490). [Abstract]

Myschik, J., McBurney, W. T., Rades, T., & Hook, S. (2005). Formulation and characterisation of Quil-A containing solid lipid implants. In E. A. Davis & C. G. Sobey (Eds.), Proceedings of the Joint Meeting of Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and Australasian Pharmaceutical Science Association. 11. [Abstract]

Lendemans, D. G., McBurney, W. B., Hennessy, T., Rades, T., & Hook, S. (2005). In vitro activation of dendritic cells by cationic formulations containing DC-cholestrol, phospholipid and Quil-A. In E. A. Davis & C. G. Sobey (Eds.), Proceedings of the Joint Meeting of Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and Australasian Pharmaceutical Science Association. 11. [Abstract]

Saupe, A., Hennessy, T. M., McBurney, W. T., Rades, T., & Hook, S. (2005). Chitosan nanoparticulate dispersions for vaccine delivery: Preparation and immunological characterisation. In E. A. Davis & C. G. Sobey (Eds.), Proceedings of the Joint Meeting of Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and Australasian Pharmaceutical Science Association. 11. [Abstract]

Saupe, A., Hennessy, T. M., McBurney, W. T., Rades, T., & Hook, S. (2005). Chitosan nanoparticulate dispersions for vaccine delivery: Preparation and immunological characterisation. Proceedings of the ASCEPT-APSA Joint Annual Scientific Meeting. [Abstract]

Krauel, K., Hook, S., Davies, N., & Rades, T. (2005). Physical-chemical characterisation of a microemulsion template used for interfacial polymerisation to form nanoparticles. Proceedings of the 22nd New Zealand Conference on Microscopy. (pp. 81). [Abstract]

Egert, A. M., Lendemans, D. G., Hook, S., & Rades, T. (2005). Characterisation of dispersions containing Quillaja saponins and cationic lipids. Deutsche Pharmazeutische Gesellschaft. 8(5), (pp. 145). [Abstract]

Conference Contribution - Verbal presentation and other Conference outputs

Hook, S. (2005, December). The use of flow cytometry for pharmaceutic research. Verbal presentation at the Joint Meeting of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists & the Australasian Pharmaceutical Science Association, Melbourne, Australia.

2004

Journal - Research Article

White, K., Kearns, P., Toth, I., & Hook, S. (2004). Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology & Cell Biology, 82, 517-522. doi: 10.1111/j.0818-9641.2004.01269.x

Marsland, B. J., Harris, N. L., Camberis, M., Kopf, M., Hook, S. M., & Le Gros, G. (2004). Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells. PNAS, 101(16), 6116-6121.

Demana, P. H., Fehske, C., White, K., Rades, T., & Hook, S. (2004). Effect of incorporation of the adjuvant Quil A on structure and immune stimulatory capacity of liposomes. Immunology & Cell Biology, 82, 547-554.

Conference Contribution - Published proceedings: Full paper

White, K., Rades, T., Furneaux, R., Tyler, P., & Hook, S. (2004). Comparison of the ability of mannose conjugated liposomes to stimulate human and murine dendritic cells. In A. McDowell (Ed.), Proceedings of the 31st Annual Meeting and Exposition of the Controlled Release Society. [CD-ROM] [Full Paper]

White, K., Rades, T., Dähne, L., Baude, B., & Hook, S. (2004). Uptake of polyelectrolyte nanocapsules by dendritic cells - Does size matter? In A. McDowell (Ed.), Proceedings of the 31st Annual Meeting and Exposition of the Controlled Release Society. [CD-ROM] [Full Paper]

Conference Contribution - Published proceedings: Abstract

White, K. L., Rades, T., Toth, I., & Hook, S. (2004). Surface modified Quil A containing liposomes as adjuvants for vaccines. Proceedings of the Australasian Pharmaceutical Science Association: Towards Safer Medicines. (pp. 68). APSA. [Abstract]

Hook, S. (2004). Increasing the efficacy of sub-unit vaccines. Proceedings of the Australasian Pharmaceutical Science Association: Towards Safer Medicines. (pp. 47). APSA. [Abstract]

Lendemans, D. G., Myschik, J., Hook, S., & Rades, T. (2004). Pluscoms - Cationic immunostimulating complexes. Proceedings of the Australasian Pharmaceutical Science Association: Towards Safer Medicines. (pp. 66). APSA. [Abstract]

Lendemans, D. G., Myschik, J., Hook, S., & Rades, T. (2004). Iscoms made by ethanol injection. Proceedings of the Australasian Pharmaceutical Science Association: Towards Safer Medicines. (pp. 67). APSA. [Abstract]

Conference Contribution - Poster Presentation (not in published proceedings)

Demana, P. H., Davies, N. M., Hook, S., & Rades, T. (2004, December). Releasing ISCOMs upon hydration of Quil A-lipid powder formulations. Poster session presented at the 27th Annual Meeting of the Australasian Flow Cytometry Group, Adelaide, South Australia.

Lendemans, D. G., Myschik, J., Rades, T., & Hook, S. (2004, December). Cationic Quil-A containing cage-like particles. Poster session presented at the 27th Annual Meeting of the Australasian Flow Cytometry Group, Adelaide, South Australia.

Demana, P. H., Fehske, C., White, K., Rades, T., & Hook, S. (2004, December). Effect of Quil-A content in immune stimulating complexes (ISCOMS) on particle structure and immune stimulatory capacity. Poster session presented at the 27th Annual Meeting of the Australasian Flow Cytometry Group, Adelaide, South Australia.

Conference Contribution - Verbal presentation and other Conference outputs

White, K., Gordon, S., Rades, T., & Hook, S. (2004, December). Immunogenicity of lipid core peptide and Quil A containing liposomes. Verbal presentation at the 27th Annual Meeting of the Australasian Flow Cytometry Group, Adelaide, South Australia.

2003

Journal - Research Article

Hook, S. M., Camberis, M., Prout, M., & Le Gros, G. (2003). Absence of preproenkephalin increases the threshold for T cell activation. Journal of Neuroimmunology, 140, 61-68.

Conference Contribution - Published proceedings: Abstract

Demana, P. H., Davies, N. M., Hook, S. M., Vosgerau, U., Berger, B., & Rades, T. (2003). Factors influencing formation of ISCOMs and related colloidal particles prepared by the lipid film hydration method. In I. Ramzan, J. Brien & C. Armour (Eds.), Proceedings of the Annual Conference of the Australasian Pharmaceutical Science Association: Integrating Research into Practice. (pp. 103). Sydney: APSA. [Abstract]

Demana, P. H., Davies, N. M., Hook, S. M., Berger, B., & Rades, T. (2003). Pseudo-ternary phase diagrams following hydration or dialysis of Quil A-Lipid systems. In I. Ramzan, J. Brien & C. Armour (Eds.), Proceedings of the Annual Conference of the Australasian Pharmaceutical Science Association: Integrating Research into Practice. (pp. 102). Sydney: APSA. [Abstract]

Demana, P. H., Davies, N. M., Hook, S. M., Berger, B., & Rades, T. (2003). Quil A-lipid systems as antigen carriers. In I. Ramzan, J. Brien & C. Armour (Eds.), Proceedings of the Annual Conference of the Australasian Pharmaceutical Science Association: Integrating Research into Practice. (pp. 102). Sydney: APSA. [Abstract]

2002

Journal - Research Article

Hook, S. M., & Le Gros, G. (2002). Immunomodulatory effects of preproenkephalin. Current Opinions in European Medicine, 3, 68-80.

Other Research Output

Hook, S. M., & Le Gros, G. (2002). Immunomodulatory effects of preproenkephalin. Current Opinions in European Medicine. VICER Publishing. [Other Research Output].

2000

Journal - Research Article

Hook, S. M., Prout, M., Camberis, M., Konig, M., Zimmer, A., & Le Gros, G. (2000). Th2 dependent airway eosinophilia is regulated by preproenkephalin. Journal of Neuroimmunology, 107, 59-65.

Conference Contribution - Published proceedings: Abstract

Armstrong, D. S., Hook, S. M., Carzino, R., Nixon, G. M., & Grimwood, K. (2000). Lower airway inflammation in cystic fibrosis infants. Pediatric Pulmonology. Proceedings of the Fourteenth Annual North American Cystic Fibrosis Conference. supplement, (pp. s5.3). [Abstract]

1999

Journal - Research Article

Hook, S., Cheng, P., Holloway, J. W., Riley, G., Sawyer, G., Le Gros, G., & Beasley, R. (1999). Analysis of two IL-4 promoter polymorphisms in a cohort of atopic and asthmatic subjects. Experimental & Clinical Immunogenetics, 16(1), 33-35. doi: 10.1159/000019094

Kirman, J., McCoy, K. D., Hook, S., Prout, M., Delahunt, B., Orme, I., … Le Gros, G. (1999). CTLA-4 blockade enhances the immune response induced by mycobacterial infection but does not lead to increased protection. Infection & Immunity, 67(8), 3786-3792.

Hook, S., Camberis, M., Prout, M., Konig, M., Zimmer, A., van Heeke, G., & Le Gros, G. (1999). Preproenkephalin is a Th2 cytokine but is not required for Th2 differentiation in vitro. Immunology & Cell Biology, 77, 385-390. doi: 10.1046/j.1440-1711.1999.00842.x

1996

Journal - Research Article

Hook, S., Griffin, F., Mackintosh, C., & Buchan, G. (1996). Activation of an interleukin-4 mRNA-producing population of peripheral blood mononuclear cells after infection with Mycobacterium bovis or vaccination with killed, but not live, BCG. Immunology, 88, 269-274.

1995

Chapter in Book - Research

Buchan, G. S., Lockhart, D., Slobbe, L., Chinn, N., Hook, S., Thomson, A., & Griffin, F. (1995). Vaccination: Can it be improved? In F. Griffin & G. de Lisle (Eds.), Tuberculosis in wildlife and domestic animals. (pp. 116-120). Dunedin: Otago University Press.

Lockhart, E., Slobbe, L., Hook, S., Griffin, F., & Mackintosh, C. G. (1995). The development of a new, multipurpose, animal model of tuberculosis. In F. Griffin & G. de Lisle (Eds.), Tuberculosis in wildlife and domestic animals. (pp. 158-160). Dunedin: Otago University Press.

Hook, S., Slobbe, L., Chinn, N., Griffin, J. F. T., & Hesketh, J. B. (1995). Measuring cytokine responses to vaccination with live and killed BCG. In F. Griffin & G. de Lisle (Eds.), Tuberculosis in wildlife and domestic animals. (pp. 128-130). Dunedin: Otago University Press.