Contact Details
University Links
- Position
- PhD Student
- Department
- Department of Physiology
- Qualifications
- BSc(Hons)
- Research summary
- Investigating if fructose could also effect the pancreatic beta cells
Research
Diabetes Mellitus afflicts more than 400 million people worldwide, but the enigmatic causes has slowed the progress of treatment. Type 2 Diabetes Mellitus accounts for 90% of all cases, and is characterised by insulin resistance and pancreatic beta cell dysfunction.
Fructose is a sugar which has been consumed more and more (i.e. high fructose corn syrup) over the past 50 years, in parallel with the rising diabetes and obesity rates. When fructose is metabolised, the reaction causes an increase in production of uric acid, which has been shown to have direct effects on insulin resistance in the liver. Could fructose also effect the pancreatic beta cells?
Lyth, D., Ware, A., & Bahn, A. (2022, August-September). Does hyperuricemia drive breast cancer metastasis via changes in TGFβ signalling? Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Alimoradi, H., Thomas, A., Lyth, D. D. B., Barzegar-Fallah, A., Matikonda, S. S., Gamble, A. B., & Giles, G. I. (2022). SMA-BmobaSNO: An intelligent photoresponsive nitric oxide releasing polymer for drug nanoencapsulation and targeted delivery. Nanotechnology, 33, 195101. doi: 10.1088/1361-6528/ac4eb0 Journal - Research Article