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Disturbance of the ‘Cellular uric acid homeostasis’ as the driver for diabetes mellitus, hypertension and cancer

A postgraduate research opportunity at the University of Otago.

Details

Academic background
Sciences, Health Sciences
Host campus
Dunedin
Qualifications
Master’s, PhD
Department
Physiology
Supervisor
Dr Andrew Bahn

Overview

My group is interested in how uric acid controls major intracellular metabolic signalling pathways (mTOR, AMPK) in order to understand the onset of diabetes mellitus, hypertension and cancer. Uric acid transporters and especially GLUT9 are emerging as major players for ‘cellular uric acid homeostasis’ in many tissues controlling cellular redox and energy homeostasis and ultimately cell fate and survival.

Students who are interested in the topic and keen to meet a challenge to perform state of the art research are encouraged to apply.

Contact

Andrew Bahn
Email   andrew.bahn@otago.ac.nz