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Contact Details

Phone
+64 3 479 7105
Email
trudy.milne@otago.ac.nz
Position
Senior Research Fellow
Qualifications
NZCS PhD
Research summary
Oral health

Research

Dr Milne's research continues in a number of oral health areas including endodontics, periodontology and orthodontics.

Investigation of periodontopathogens and their association with angiogenic and inflammatory gene expression in dental pulp continues with the hope of improved dental treatment outcomes for smokers and patients with Type 2 diabetes. A study of a grafting material in a bone-healing sheep model and the genes associated with osteogenesis aims to advance the development of implant options for dental patients.

Dr Milne is also investigating the role osteoblasts and periodontal ligament cells play in the immune response and bone remodelling during orthodontic tooth movement.

Publications

Patel, S., Yang, E., Milne, T. J., Hussaini, H., Cooper, P. R., & Friedlander, L. T. (2024). Angiogenic effects of type 2 diabetes on the dental pulp. International Endodontic Journal. Advance online publication. doi: 10.1111/iej.14181 Journal - Research Article

Alsamahi, S., Milne, T. J., Hussaini, H. M., Rich, A. M., Cooper, P. R., & Friedlander, L. T. (2023). Effects of glycation end-products on the dental pulp in patients with type 2 diabetes. International Endodontic Journal, 56, 1373-1384. doi: 10.1111/iej.13966 Journal - Research Article

Ram, A., Duncan, W. J., Coates, D. E., Nobakht, S., Tkatchenko, T., & Milne, T. J. (2023). Bone remodelling marker expression in grafted and ungrafted sheep tooth extraction sockets: A comparative randomised study. Archives of Oral Biology, 153, 105738. doi: 10.1016/j.archoralbio.2023.105738 Journal - Research Article

Nobakht, S., Milne, T. J., Duncan, W. J., Ram, A., Tkatchenko, T., Dong, Z., & Coates, D. E. (2023). Expression of the pleiotrophin–midkine axis in a sheep tooth socket model of bone healing. Journal of Periodontal Research, 58, 109-121. doi: 10.1111/jre.13073 Journal - Research Article

AlSamahi, S., Milne, T. J., Hussaini, H., Rich, A. M., & Friedlander, L. T. (2022). Type 2 diabetes and the clinically normal pulp: An in-vitro study. International Endodontic Journal, 55, 660-671. doi: 10.1111/iej.13732 Journal - Research Article

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