Professor Iain Lamont

Contact Details
- Phone
- 64 3 479 7869
- iain.lamont@otago.ac.nz
University Links
- Position
- Professor
- Department
- Department of Biochemistry
- Qualifications
- BSc (Edin) DPhil (Oxon)
- Research summary
- Molecular basis of infectious disease
- Teaching
- Biochemistry; genetics; molecular biology
- Clinical
- Interests: cystic fibrosis; bronchiectasis, antibiotic resistance
Research
Iain has a long-standing interest in the molecular genetics of bacteria that cause infectious disease.
He and his research team have a particular focus on the pathogenic bacterium Pseudomonas aeruginosa that causes a wide range of infections such as chronic infections in patients in cystic fibrosis.
During infection the bacteria secrete a number of agents that contribute to the pathogenic process. These include numerous proteins and an iron-scavenging compound called pyoverdine. Iain and his team are also using a wide range of biochemical, molecular biological, and genetic approaches to study the way in which pyoverdine contributes to infection and how it is made.
P. aeruginosa become very resistant to antibiotics during infection and highly resistant strains ("superbugs") are some of the most problematic infectious bacteria on the planet. Iain and his research team are using genetic, bioinformatic and molecular approaches to understand how P. aeruginosa becomes resistant to antibiotics with the long term goal of better management of infections.
Current research areas include:
Understanding how P. aeruginosa resists antibiotics
How does P. aeruginosa exist in the environment, and during infection?
Genomics and comparative genomics of Pseudomonas
Publications
Erdmann, M. B., Gardner, P. P., & Lamont, I. L. (2023). The PitA protein contributes to colistin susceptibility in Pseudomonas aeruginosa. PLoS ONE, 18(10), e0292818. doi: 10.1371/journal.pone.0292818
Wei, X., Gao, J., Xu, C., Pan, X., Jin, Y., Bai, F., … Lamont, I. L., Pletzer, D., & Wu, W. (2023). Murepavadin induces envelope stress response and enhances the killing efficacies of β-lactam antibiotics by impairing the outer membrane integrity of Pseudomonas aeruginosa. Microbiology Spectrum. Advance online publication. doi: 10.1128/spectrum.01257-23
Martin, L. W., Gray, A. R., Brockway, B., & Lamont, I. L. (2023). Pseudomonas aeruginosa is oxygen-deprived during infection in cystic fibrosis lungs, reducing the effectiveness of antibiotics. FEMS Microbiology Letters, fnad076. Advance online publication. doi: 10.1093/femsle/fnad076
Ramsay, K. A., Rehman, A., Taylor Wardell, S., Martin, L. W., Bell, S. C., Patrick, W. M., … Lamont, I. L. (2023). Ceftazidime resistance in Pseudomonas aeruginosa is multigenic and complex. PLoS ONE, 18(5), e0285856. doi: 10.1371/journal.pone.0285856
Thacharodi, A., & Lamont, I. L. (2023). Gene-gene interactions reduce aminoglycoside susceptibility of Pseudomonas aeruginosa through efflux pump-dependent and -independent mechanisms. Antibiotics, 12, 152. doi: 10.3390/antibiotics12010152
Brumby, A. M., Lamont, I. L., Dodd, I. B., Egan, J. B., Walling, G. A., McEwan, J. C., … Montgomery, G. (1996). Defining the SOS operon of coliphage 186. N/A, 114p.
Authored Book - Research
Brinkman, F. S. L., Winson, G. L., Done, R. E., Filloux, A., Francis, V. I., Goldberg, J. B., … Lamont, I. L., … Welch, M. (2021). The Pseudomonas aeruginosa whole genome sequence: A 20th anniversary celebration. In R. K. Poole & D. J. Kelly (Eds.), Advances in microbial physiology. (pp. 25-88). London, UK: Elsevier. doi: 10.1016/bs.ampbs.2021.07.001
Chapter in Book - Research
Erdmann, M. B., Gardner, P. P., & Lamont, I. L. (2023). The PitA protein contributes to colistin susceptibility in Pseudomonas aeruginosa. PLoS ONE, 18(10), e0292818. doi: 10.1371/journal.pone.0292818
Journal - Research Article
Martin, L. W., Gray, A. R., Brockway, B., & Lamont, I. L. (2023). Pseudomonas aeruginosa is oxygen-deprived during infection in cystic fibrosis lungs, reducing the effectiveness of antibiotics. FEMS Microbiology Letters, fnad076. Advance online publication. doi: 10.1093/femsle/fnad076
Journal - Research Article
Ramsay, K. A., Rehman, A., Taylor Wardell, S., Martin, L. W., Bell, S. C., Patrick, W. M., … Lamont, I. L. (2023). Ceftazidime resistance in Pseudomonas aeruginosa is multigenic and complex. PLoS ONE, 18(5), e0285856. doi: 10.1371/journal.pone.0285856
Journal - Research Article
Thacharodi, A., & Lamont, I. L. (2023). Gene-gene interactions reduce aminoglycoside susceptibility of Pseudomonas aeruginosa through efflux pump-dependent and -independent mechanisms. Antibiotics, 12, 152. doi: 10.3390/antibiotics12010152
Journal - Research Article
Wei, X., Gao, J., Xu, C., Pan, X., Jin, Y., Bai, F., … Lamont, I. L., Pletzer, D., & Wu, W. (2023). Murepavadin induces envelope stress response and enhances the killing efficacies of β-lactam antibiotics by impairing the outer membrane integrity of Pseudomonas aeruginosa. Microbiology Spectrum. Advance online publication. doi: 10.1128/spectrum.01257-23
Journal - Research Article
Adhikari, B. R., Sinha, S., Lyons, N., Pletzer, D., Lamont, I., Gordon, K. C., & Das, S. C. (2022). Inhalable ceftazidime-roflumilast powder targeting infection and inflammation: Influence of incorporating roflumilast into ceftazidime-leucine co-amorphous formulation. European Journal of Pharmaceutics & Biopharmaceutics. Advance online publication. doi: 10.1016/j.ejpb.2022.10.005
Journal - Research Article
Thacharodi, A., & Lamont, I. L. (2022). Aminoglycoside resistance in Pseudomonas aeruginosa: The contribution of the MexXY-OprM efflux pump varies between isolates. Journal of Medical Microbiology, 71(6), 001551. doi: 10.1099/jmm.0.001551
Journal - Research Article
Thacharodi, A., & Lamont, I. L. (2022). Aminoglycoside-modifying enzymes are sufficient to make Pseudomonas aeruginosa clinically resistant to key antibiotics. Antibiotics, 11(7), 884. doi: 10.3390/antibiotics11070884
Journal - Research Article
Glen, K. A., & Lamont, I. L. (2021). β-lactam resistance in Pseudomonas aeruginosa: Current status, future prospects. Pathogens, 10(12), 1638. doi: 10.3390/pathogens10121638
Journal - Research Article
Moore, M. P., Lamont, I. L., Williams, D., Paterson, S., Kukavica-Ibrulj, I., Tucker, N. P., … Winstanley, C. (2021). Transmission, adaptation and geographical spread of the Pseudomonas aeruginosa Liverpool epidemic strain. Microbial Genomics, 7, 000511. doi: 10.1099/mgen.0.000511
Journal - Research Article
Philem, P., Kleffmann, T., Gai, S., Hawkins, B. C., Wilbanks, S. M., & Lamont, I. L. (2021). Identification of active site residues of the siderophore synthesis enzyme PvdF and evidence for interaction of PvdF with a substrate-providing enzyme. International Journal of Molecular Sciences, 22(4), 2211. doi: 10.3390/ijms22042211
Journal - Research Article
Ramsay, K. A., McTavish, S. M., Wardell, S. J. T., & Lamont, I. L. (2021). The effects of sub-inhibitory antibiotic concentrations on Pseudomonas aeruginosa: Reduced susceptibility due to mutations. Frontiers in Microbiology, 12, 789550. doi: 10.3389/fmicb.2021.789550
Journal - Research Article
Rehman, A., Jeukens, J., Levesque, R. C., & Lamont, I. L. (2021). Gene-gene interactions dictate ciprofloxacin resistance in Pseudomonas aeruginosa and facilitate prediction of resistance phenotype from genome sequence data. Antimicrobial Agents & Chemotherapy, 65(7), e02696. doi: 10.1128/aac.02696-20
Journal - Research Article
Wardell, S. J. T., Gauthier, J., Martin, L. W., Potvin, M., Brockway, B., Levesque, R. C., & Lamont, I. L. (2021). Genome evolution drives transcriptomic and phenotypic adaptation in Pseudomonas aeruginosa during 20 years of infection. Microbial Genomics, 7(11), 681. doi: 10.1099/mgen.0.000681
Journal - Research Article
Mettrick, K., Hassan, K., Lamont, I., & Reid, D. (2020). The Iron-chelator, N,N'-bis (2-hydroxybenzyl) ethylenediamine-N,N'-diacetic acid is an effective colistin adjunct against clinical strains of biofilm-dwelling Pseudomonas aeruginosa. Antibiotics, 9(4), 144. doi: 10.3390/antibiotics9040144
Journal - Research Article
Casas Garcia, G. P., Perugini, M. A., Lamont, I. L., & Maher, M. J. (2019). The purification of the σFpvI/FpvR20 and σPvdS/FpvR20 protein complexes is facilitated at room temperature. Protein Expression & Purification, 160, 11-18. doi: 10.1016/j.pep.2019.03.005
Journal - Research Article
Forester, N. T., Lane, G. A., McKenzie, C. M., Lamont, I. L., & Johnson, L. J. (2019). The role of SreA-mediated iron regulation in maintaining Epichloë festucae-Lolium perenne symbioses. Molecular Plant-Microbe Interactions, 32(10), 1324-1335. doi: 10.1094/mpmi-03-19-0060-r
Journal - Research Article
Thomson, J. M., & Lamont, I. L. (2019). Nucleoside analogues as antibacterial agents. Frontiers in Microbiology, 10. doi: 10.3389/fmicb.2019.00952
Journal - Research Article
Wardell, S. J. T., Rehman, A., Martin, L. W., Winstanley, C., Patrick, W. M., & Lamont, I. L. (2019). A large-scale whole-genome comparison shows that experimental evolution in response to antibiotics predicts changes in naturally evolved clinical Pseudomonas aeruginosa. Antimicrobial Agents & Chemotherapy, 63(12), e01619-19. doi: 10.1128/aac.01619-19
Journal - Research Article
Forester, N. T., Lane, G. A., Steringa, M., Lamont, I. L., & Johnson, L. J. (2018). Contrasting roles of fungal siderophores in maintaining iron homeostasis in Epichloë festucae. Fungal Genetics & Biology, 111, 60-72. doi: 10.1016/j.fgb.2017.11.003
Journal - Research Article
Martin, L. W., Robson, C. L., Watts, A. M., Gray, A. R., Wainwright, C. E., Bell, S. C., Ramsay, K. A., … Brockway, B., & Lamont, I. L. (2018). Expression of Pseudomonas aeruginosa antibiotic resistance genes varies greatly during infections in cystic fibrosis patients. Antimicrobial Agents & Chemotherapy, 62(11), e01789-18. doi: 10.1128/AAC.01789-18
Journal - Research Article
Mastropasqua, M. C., Lamont, I., Martin, L. W., Reid, D. W., D'Orazio, M., & Battistoni, A. (2018). Efficient zinc uptake is critical for the ability of Pseudomonas aeruginosa to express virulence traits and colonize the human lung. Journal of Trace Elements in Medicine & Biology, 48, 74-80. doi: 10.1016/j.jtemb.2018.03.009
Journal - Research Article
Wee, B. A., Tai, A. S., Sherrard, L. J., Ben Zakour, N. L., Hanks, K. R., Kidd, T. J., Ramsay, K. A., Lamont, I., … Beatson, S. A. (2018). Whole genome sequencing reveals the emergence of a Pseudomonas aeruginosa shared strain sub-lineage among patients treated within a single cystic fibrosis centre. BMC Genomics, 19, 644. doi: 10.1186/s12864-018-5018-x
Journal - Research Article
Bishop, T. F., Martin, L. W., & Lamont, I. L. (2017). Activation of a cell surface signaling pathway in Pseudomonas aeruginosa requires ClpP protease and new sigma factor synthesis. Frontiers in Microbiology, 8, 2442. doi: 10.3389/fmicb.2017.02442
Journal - Research Article
Edgar, R. J., Hampton, G. E., Casas Garcia, G. P., Maher, M. J., Perugini, M. A., Ackerley, D. F., & Lamont, I. L. (2017). Integrated activities of two alternative sigma factors coordinate iron acquisition and uptake by Pseudomonas aeruginosa. Molecular Microbiology, 106(6), 891-904. doi: 10.1111/mmi.13855
Journal - Research Article
Hilliam, Y., Moore, M. P., Lamont, I. L., Bilton, D., Haworth, C. S., Foweraker, J., … Winstanley, C. (2017). Pseudomonas aeruginosa adaptation and diversification in the non-cystic fibrosis bronchiectasis lung. European Respiratory Journal, 49(4), 1602108. doi: 10.1183/13993003.02108-2016
Journal - Research Article
Nunn, S., & Lamont, I. (2017). Beauty is the beast. Junctures, 2017(18), 100-105.
Journal - Research Article
Germoni, L. A. P., Bremer, P. J., & Lamont, I. L. (2016). The effect of alginate lyase on the gentamicin resistance of Pseudomonas aeruginosa in mucoid biofilms. Journal of Applied Microbiology, 121(1), 126-135. doi: 10.1111/jam.13153
Journal - Research Article
Donaldson, A. E., & Lamont, I. L. (2015). Metabolomics of post-mortem blood: Identifying potential markers of post-mortem interval. Metabolomics, 11(1), 237-245. doi: 10.1007/s11306-014-0691-5
Journal - Research Article
Freschi, L., Jeukens, J., Kukavica-Ibrulj, I., Boyle, B., Dupont, M.-J., LaRoche, J., … Lamont, I. L., … Levesque, R. C. (2015). Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium. Frontiers in Microbiology, 6, 1036. doi: 10.3389/fmicb.2015.01036
Journal - Research Article
Lopez-Medina, E., Fan, D., Coughlin, L. A., Ho, E. X., Lamont, I. L., Reimmann, C., … Koh, A. Y. (2015). Candida albicans inhibits Pseudomonas aeruginosa virulence through suppression of pyochelin and pyoverdine biosynthesis. PLoS Pathogens, 11(8), e1005129. doi: 10.1371/journal.ppat.1005129
Journal - Research Article
Tchesnokov, E. P., Fellner, M., Siakkou, E., Kleffmann, T., Martin, L. W., Aloi, S., Lamont, I. L., Wilbanks, S. M., & Jameson, G. N. L. (2015). The cysteine dioxygenase homologue from Pseudomonas aeruginosa is a 3-mercaptopropionate dioxygenase. Journal of Biological Chemistry, 290(40), 24424-24437. doi: 10.1074/jbc.M114.635672
Journal - Research Article
Calcott, M. J., Owen, J. G., Lamont, I. L., & Ackerley, D. F. (2014). Biosynthesis of novel pyoverdines by domain substitution in a non-ribosomal peptide synthetase of Pseudomonas aeruginosa. Applied & Environmental Microbiology, 80(18), 5723-5731. doi: 10.1128/aem.01453-14
Journal - Research Article
Donaldson, A. E., & Lamont, I. L. (2014). Estimation of post-mortem interval using biochemical markers. Australian Journal of Forensic Sciences, 46(1), 8-26. doi: 10.1080/00450618.2013.784356
Journal - Research Article
Edgar, R. J., Xu, X., Shirley, M., Konings, A. F., Martin, L. W., Ackerley, D. F., & Lamont, I. L. (2014). Interactions between an anti-sigma protein and two sigma factors that regulate the pyoverdine signaling pathway in Pseudomonas aeruginosa. BMC Microbiology, 14, 287. doi: 10.1186/s12866-014-0287-2
Journal - Research Article
Llamas, M. A., Imperi, F., Visca, P., & Lamont, I. L. (2014). Cell-surface signaling in Pseudomonas: Stress responses, iron transport and pathogenicity. FEMS Microbiology Reviews, 38, 569-597. doi: 10.1111/1574-6976.12078
Journal - Research Article
Nguyen, A. T., O'Neill, M. J., Watts, A. M., Robson, C. L., Lamont, I. L., Wilks, A., & Oglesby-Sherrouse, A. G. (2014). Adaptation of iron homeostasis pathways by a Pseudomonas aeruginosa pyoverdine mutant in the cystic fibrosis lung. Journal of Bacteriology, 196(12), 2265-2276. doi: 10.1128/JB.01491-14
Journal - Research Article
Butler, M. I., Stockwell, P. A., Black, M. A., Day, R. C., Lamont, I. L., & Poulter, R. T. M. (2013). Pseudomonas syringae pv. actinidiae from recent outbreaks of kiwifruit bacterial canker belong to different clones that originated in China. PLoS ONE, 8(2), e57464. doi: 10.1371/journal.pone.0057464
Journal - Research Article
Donaldson, A. E., & Lamont, I. L. (2013). Biochemistry changes that occur after death: Potential markers for determining post-mortem interval. PLoS ONE, 8(11), e82011. doi: 10.1371/journal.pone.0082011
Journal - Research Article
Konings, A. F., Martin, L. W., Sharples, K. J., Roddam, L. F., Latham, R., Reid, D. W., & Lamont, I. L. (2013). Pseudomonas aeruginosa uses multiple pathways to acquire iron during chronic infection in cystic fibrosis lungs. Infection & Immunity, 81(8), 2697-2704. doi: 10.1128/IAI.00418-13
Journal - Research Article
Reid, D. W., Latham, R., Lamont, I. L., Camara, M., & Roddam, L. F. (2013). Molecular analysis of changes in Pseudomonas aeruginosa load during treatment of a pulmonary exacerbation in cystic fibrosis. Journal of Cystic Fibrosis, 12, 688-699. doi: 10.1016/j.jcf.2013.03.008
Journal - Research Article
Smith, D. J., Lamont, I. L., Anderson, G. J., & Reid, D. W. (2013). Targeting iron uptake to control Pseudomonas aeruginosa infections in cystic fibrosis. European Respiratory Journal, 42(6), 1723-1736. doi: 10.1183/09031936.00124012
Journal - Research Article
Donaldson, A. E., Walker, N. K., Lamont, I. L., Cordiner, S. J., & Taylor, M. C. (2011). Characterising the dynamics of expirated bloodstain pattern formation using high-speed digital video imaging. International Journal of Legal Medicine, 125, 757-762. doi: 10.1007/s00414-010-0498-5
Journal - Research Article
Draper, R. C., Martin, L. W., Beare, P. A., & Lamont, I. L. (2011). Differential proteolysis of sigma regulators controls cell-surface signaling in Pseudomonas aeruginosa. Molecular Microbiology, 82(6), 1444-1453. doi: 10.1111/j.1365-2958.2011.07901.x
Journal - Research Article
Martin, L. W., Reid, D. W., Sharples, K. J., & Lamont, I. L. (2011). Pseudomonas siderophores in the sputum of patients with cystic fibrosis. Biometals, 24(6), 1059-1067. doi: 10.1007/s10534-011-9464-z
Journal - Research Article
Upritchard, H. G., Yang, J., Bremer, P. J., Lamont, I. L., & McQuillan, A. J. (2011). Adsorption of enterobactin to metal oxides and the role of siderophores in bacterial adhesion to metals. Langmuir, 27(17), 10587-10596. doi: 10.1021/la202352j
Journal - Research Article
Donaldson, A., Taylor, M. C., Cordiner, S. J., & Lamont, I. L. (2010). Using oral microbial DNA analysis to identify expirated bloodspatter. International Journal of Legal Medicine, 124(6), 569-576. doi: 10.1007/s00414-010-0426-8
Journal - Research Article
McMillan, D. G. G., Velasquez, I., Nunn, B. L., Goodlett, D. R., Hunter, K. A., Lamont, I., Sander, S. G., & Cook, G. M. (2010). Acquisition of iron by alkaliphilic Bacillus species. Applied & Environmental Microbiology, 76(20), 6955-6961. doi: 10.1128/AEM.01393-10
Journal - Research Article
Nakatani, Y., Lamont, I. L., & Cutfield, J. F. (2010). Discovery and characterization of a distinctive exo-1,3/1,4-β-glucanase from the marine bacterium Pseudoalteromonas sp. strain BB1. Applied & Environmental Microbiology, 76(20), 6760-6768. doi: 10.1128/AEM.00758-10
Journal - Research Article
Yeterian, E., Martin, L. W., Guillon, L., Journet, L., Lamont, I. L., & Schalk, I. J. (2010). Synthesis of the siderophore pyoverdine in Pseudomonas aeruginosa involves a periplasmic maturation. Amino Acids, 38(5), 1447-1459. doi: 10.1007/s00726-009-0358-0
Journal - Research Article
Yeterian, E., Martin, L. W., Lamont, I. L., & Schalk, I. J. (2010). An efflux pump is required for siderophore recycling by Pseudomonas aeruginosa. Environmental Microbiology Reports, 2(3), 412-418. doi: 10.1111/j.1758-2229.2009.00115.x
Journal - Research Article
Lamont, I. L., Konings, A. F., & Reid, D. W. (2009). Iron acquisition by Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis. Biometals, 22(1), 53-60. doi: 10.1007/s10534-008-9197-9
Journal - Research Article
Mettrick, K. A., & Lamont, I. L. (2009). Different roles for anti-sigma factors in siderophore signalling pathways of Pseudomonas aeruginosa. Molecular Microbiology, 74(5), 1257-1271. doi: 10.1111/j.1365-2958.2009.06932.x
Journal - Research Article
Ramsay, J. P., Sullivan, J. T., Jambari, N., Ortori, C. A., Heeb, S., Williams, P., … Lamont, I. L., & Ronson, C. W. (2009). A LuxRI-family regulatory system controls excision and transfer of the Mesorhizobium loti strain R7A symbiosis island by activating expression of two conserved hypothetical genes. Molecular Microbiology, 73(6), 1141-1155. doi: 10.1111/j.1365-2958.2009.06843.x
Journal - Research Article
Reid, D. W., Anderson, G. J., & Lamont, I. L. (2009). Role of lung iron in determining the bacterial and host struggle in cystic fibrosis. American Journal of Physiology: Lung Cellular & Molecular Physiology, 297(5), L795-L802. doi: 10.1152/ajplung.00132.2009
Journal - Research Article
Schalk, I. J., Lamont, I. L., & Cobessi, D. (2009). Structure-function relationships in the bifunctional ferrisiderophore FpvA receptor from Pseudomonas aeruginosa. Biometals, 22(4), 671-678. doi: 10.1007/s10534-008-9203-2
Journal - Research Article
Shirley, M., & Lamont, I. L. (2009). Role of TonB1 in pyoverdine-mediated signaling in Pseudomonas aeruginosa. Journal of Bacteriology, 191(18), 5634-5640. doi: 10.1128/JB.00742-09
Journal - Research Article
Spencer, M. R., Beare, P. A., & Lamont, I. L. (2008). Role of cell surface signaling in proteolysis of an alternative sigma factor in Pseudomonas aeruginosa. Journal of Bacteriology, 190(14), 4865-4869.
Journal - Research Article
Upritchard, H. G., Cordwell, S. J., & Lamont, I. L. (2008). Immunoproteomics to examine cystic fibrosis host interactions with extracellular Pseudomonas aeruginosa proteins. Infection & Immunity, 76(10), 4624-4632. doi: 10.1128/IAI.01707-07
Journal - Research Article
Carlton, T. M., Sullivan, J. T., Stuart, G. S., Hutt, K., Lamont, I. L., & Ronson, C. W. (2007). Ferrichrome utilization in a mesorhizobial population: Microevolution of a three-locus system. Environmental Microbiology, 9(12), 2923-2932.
Journal - Research Article
Diggle, S. P., Matthijs, S., Wright, V. J., Fletcher, M. P., Chhabra, S. R., Lamont, I. L., … Williams, P. (2007). The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment. Chemistry & Biology, 14, 87-96.
Journal - Research Article
Upritchard, H. G., Yang, J., Bremer, P. J., Lamont, I. L., & McQuillan, A. J. (2007). Adsorption to metal oxides of the Pseudomonas aeruginosa siderophore pyoverdine and implications for bacterial biofilm formation on metals. Langmuir, 23(13), 7189-7195.
Journal - Research Article
Visca, P., Imperi, F., & Lamont, I. L. (2007). Pyoverdine siderophores: From biogenesis to biosignificance. Trends in Microbiology, 15(1), 22-30.
Journal - Research Article
Lamont, I. L., Martin, L. W., Sims, T., Scott, A., & Wallace, M. (2006). Characterization of a gene encoding an acetylase required for pyoverdine synthesis in Pseudomonas aeruginosa. Journal of Bacteriology, 188(8), 3149-3152. doi: 10.1128/JB.188.8.3149-3152.2006
Journal - Research Article
Ramsay, J. P., Sullivan, J. T., Stuart, G. S., Lamont, I. L., & Ronson, C. W. (2006). Excision and transfer of the Mesorhizobium loti R7A symbiosis island requires an integrase IntS, a novel recombination directionality factor RdfS, and a putative relaxase RlxS. Molecular Microbiology, 62(3), 723-734. doi: 10.1111/j.1365-2958.2006.05396.x
Journal - Research Article
Wilson, M. J., & Lamont, I. L. (2006). Mutational analysis of an extracytoplasmic-function sigma factor to investigate its interactions with RNA polymerase and DNA. Journal of Bacteriology, 188(5), 1935-1942.
Journal - Research Article
Yang, J., Bremer, P. J., Lamont, I. L., & McQuillan, A. J. (2006). Infrared spectroscopic studies of siderophore-related hydroxamic acid ligands adsorbed on titanium dioxide. Langmuir, 22(24), 10109-10117.
Journal - Research Article
James, H. E., Beare, P. A., Martin, L. W., & Lamont, I. L. (2005). Mutational analysis of a bifunctional ferrisiderophore receptor and signal-transducing protein from Pseudomonas aeruginosa. Journal of Bacteriology, 187(13), 4514-4520.
Journal - Research Article
Ackerley, D. F., & Lamont, I. L. (2004). Characterization and genetic manipulation of peptide synthetases in Pseudomonas aeruginosa PAO1 in order to generate novel pyoverdines. Chemistry & Biology, 11, 971-980.
Journal - Research Article
Caradoc-Davies, T. T., Cutfield, S. M., Lamont, I. L., & Cutfield, J. F. (2004). Crystal structures of Escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium. Journal of Molecular Biology, 337, 337-354.
Journal - Research Article
Ackerley, D. F., Caradoc-Davies, T. T., & Lamont, I. L. (2003). Substrate specificity of the nonribosomal peptide synthetase PvdD from Pseudomonas aeruginosa. Journal of Bacteriology, 185(9), 2848-2855.
Journal - Research Article
Beare, P., For, R. J., Martin, L., & Lamont, I. L. (2003). Siderophore-mediated cell signalling in Pseudomonas aeruginosa: Divergent pathways regulate virulence factor production and siderophore receptor synthesis. Molecular Microbiology, 47(1), 195-207.
Journal - Research Article
Lamont, I. L., & Martin, L. (2003). Identification and characterization of novel pyoverdine synthesis genes in Pseudomonas aeruginosa. Microbiology, 149, 833-842.
Journal - Research Article
McWhirter, M. J., Bremer, P. J., Lamont, I. L., & McQuillan, A. J. (2003). Siderophore-mediated covalent bonding to metal (oxide) surfaces during biofilm initiation by Pseudomonas aeruginosa bacteria. Langmuir, 19, 3575-3577.
Journal - Research Article
Adhikari, R. P., Cook, G. M., Lamont, I., Lang, S., Heffernan, H., & Smith, J. M. B. (2002). Phenotypic and molecular characterization of community occurring, Western Samoan phage pattern methicillin-resistant Staphyococcus aureus. Journal of Antimicrobial Chemotherapy, 50, 825-831.
Journal - Research Article
Lamont, I. L., Beare, P. A., Ochsner, U., Vasil, A., & Vasil, M. L. (2002). Siderophore-mediated signaling regulates virulence factor production in Pseudomonas aeruginosa. PNAS, 99(10), 7072-7077.
Journal - Research Article
Visca, P., Leoni, L., Wilson, M. J., & Lamont, I. L. (2002). Iron transport and regulation, cell signalling and genomics: Lessons from Escherichia coli and Pseudomonas. Molecular Microbiology, 45(5), 1177-1190.
Journal - Research Article
McMorran, B. J., Shantha Kumara, H. M., Sullivan, K., & Lamont, I. L. (2001). Involvement of a transformylase enzyme in siderophore synthesis in Pseudomonas aeruginosa. Microbiology, 147, 1-8.
Journal - Research Article
Wilderman, P. J., Vasil, A. I., Johnson, Z., Wilson, M. J., Cunliffe, H. E., Lamont, I. L., & Vasil, M. L. (2001). Characterization of an endoprotease (PrpL) encoded by a PvdS-regulated gene in Pseudomonas aeruginosa. Infection & Immunity, 69(9), 5385-5394.
Journal - Research Article
Wilson, M. J., McMorran, B. J., & Lamont, I. L. (2001). Analysis of promoters recognized by PvdS, an extracytoplasmic function sigma factor protein from Pseudomonas aeruginosa. Journal of Bacteriology, 183(6), 2151-2155.
Journal - Research Article
Al-Samarrai, T. H., Zhang, N. X., Lamont, I. L., Martin, L., Kolbe, J., Wilsher, M., … Schmid, J. (2000). Simple and inexpensive but highly discriminating method of computer-assisted DNA fingerprinting of Pseudomonas aeruginosa. Journal of Clinical Microbiology, 38(12), 4445-4452.
Journal - Research Article
Wilson, M. J., & Lamont, I. L. (2000). Characterization of an ECF sigma factor protein from Pseudomonas aeruginosa. Biochemical & Biophysical Research Communications, 273(2), 578-583.
Journal - Research Article
Rae, J. L., Cutfield, J. F., & Lamont, I. L. (1997). Sequences and expression of pyruvate dehydrogenase genes from Pseudomonas aeruginosa. Journal of Bacteriology, 179(11), 3561-3571.
Journal - Research Article
McMorran, B. J., Merriman, M. E., Rombel, I. T., & Lamont, I. L. (1996). Characterisation of the pvdE gene which is required for pyoverdine synthesis in Pseudomonas aeruginosa. Gene, 176(1/2), 55-59.
Journal - Research Article
Ochsner, O. A., Johnson, Z., Lamont, I. L., Cunliffe, H. E., & Vasil, M. L. (1996). Exotoxin A production in Pseudomonas aeruginosa requires the iron-regulated pvdS gene encoding an alternative sigma factor. Molecular Microbiology, 21(5), 1019-1028. doi: 10.1046/j.1365-2958.1996.481425.x
Journal - Research Article
Cunliffe, H. E., Merriman, T. R., & Lamont, I. L. (1995). Cloning and characterization of pvdS, a gene required for pyoverdine synthesis in Pseudomonas aeruginosa: PvdS is probably an alternative sigma factor. Journal of Bacteriology, 177(10), 2744-2750. doi: 10.1128/jb.177.10.2744-2750.1995
Journal - Research Article
Harrison, S., Baker, M. G., Benschop, J., Death, R. G., French, N. P., Harmsworth, G., … Lamont, I. L., Priest, P. C., Ussher, J. E., & Murdoch, D. R. (2020). One Health Aotearoa: A transdisciplinary initiative to improve human, animal and environmental health in New Zealand. One Health Outlook, 2, 4. doi: 10.1186/s42522-020-0011-0
Journal - Research Other
Heywood, A., & Lamont, I. L. (2020). Cell envelope proteases and peptidases of Pseudomonas aeruginosa: Multiple roles, multiple mechanisms. FEMS Microbiology Reviews, 44, 857-873. doi: 10.1093/femsre/fuaa036
Journal - Research Other
Murdoch, D., Addidle, M., Andersson, H.-S., Arnold, B., Balm, M., Benschop, J., … Birch, M., … Brunton, C., … Chambers, S., … Dalton, S., … Everts, R., … Freeman, J., French, N., … Hudson, B., … Ikram, R., Jack, S., Kelly, M., Lamont, I., Maze, M. J., … Metcalf, S., … Murton, S., … Pink, R., Pithie, A., … Priest, P., Raymond, N., … Taylor, J., … Upton, A., Ussher, J., Werno, A., & Wiles, S. (2020). Politicians: Please work together to minimise the spread of COVID-19. New Zealand Medical Journal, 133(1511), 7-8. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Other
Ramsay, K. A., Wardell, S. J. T., Patrick, W. M., Brockway, B., Reid, D. W., Winstanley, C., … Lamont, I. L. (2019). Genomic and phenotypic comparison of environmental and patient-derived isolates of Pseudomonas aeruginosa suggest that antimicrobial resistance is rare within the environment. Journal of Medical Microbiology, 68, 1591-1595. doi: 10.1099/jmm.0.001085
Journal - Research Other
Rehman, A., Patrick, W. M., & Lamont, I. L. (2019). Mechanisms of ciprofloxacin resistance in Pseudomonas aeruginosa: New approaches to an old problem. Journal of Medical Microbiology, 68(1), 1-10. doi: 10.1099/jmm.0.000873
Journal - Research Other
Smith, D. J., Anderson, G. J., Lamont, I. L., Masel, P., Campbell, S. C., & Reid, D. W. (2013). Accurate assessment of systemic iron status in cystic fibrosis will avoid the hazards of inappropriate iron supplementation. Journal of Cystic Fibrosis, 12(3), 303-304. doi: 10.1016/j.jcf.2012.10.001
Journal - Research Other
Lamont, I. L. (2003). Bacterial intercellular signalling and infectious disease. Australian Biochemist, 34(2), 4-6.
Journal - Research Other
Lamont, I. L., & Beare, P. (2003). Iron uptake, cell signalling and gene expression in Pseudomonas aeruginosa. New Zealand BioScience, 12(4), 15-16.
Journal - Research Other