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Dr Nanette Schleich, Department of Radiation Therapy

Profile_NanettePhD (Dr rer nat), Diplom, Dipl-Ing(FH), PGDipSc,
CELTA, GradCertAntaStud

Senior Lecturer

Contact details

Tel 64 4 918 5692
Email nanette.schleich@otago.ac.nz

Dr Nanette Schleich is a Senior Lecturer at the Department of Radiation Therapy. Nanette also is a Radiation Oncology Medical Physicist working part-time at the Wellington Blood & Cancer Centre.

Research interests and activities

Nanette's research interests are in the area of medical physics, particularly radiation therapy and medical imaging, and include dual energy X-ray analysis and spectral X-ray CT imaging.

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Publications

Midgley, S., Schleich, N., Merchant, A., & Stevenson, A. (2019). CT dosimetry at the Australian Synchrotron for 25–100 keV photons and 35–160 mm-diameter biological specimens. Journal of Synchrotron Radiation, 26, 517-527. doi: 10.1107/S1600577518018015

Raja, A. Y., Moghiseh, M., Bateman, C. J., de Ruiter, N., Schon, B., Schleich, N., Woodfield, T. B. F., Butler, A. P. H., & Anderson, N. G. (2018). Measuring identification and quantification errors in spectral CT material decomposition. Applied Sciences, 8(3), 467. doi: 10.3390/app8030467

Anjomrouz, M., Shamshad, M., Panta, R. K., Vanden Broeke, L., Schleich, N., Atharifard, A., Raja, A., Bheesette, S., Walsh, M. F., Goulter, B. P., … Bateman, C. J., Butler, A. P. H., & Butler, P. H. (2018). Beam profile assessment in spectral CT scanners. Journal of Applied Clinical Medical Physics, 19(2), 287-297. doi: 10.1002/acm2.12260

Boman, E. L., Satherley, T. W. S., Schleich, N., Paterson, D. B., Greig, L., & Louwe, R. J. W. (2017). The validity of Acuros BV and TG-43 for high-dose-rate brachytherapy superficial mold treatments. Brachytherapy, 16(6), 1280-1288. doi: 10.1016/j.brachy.2017.08.010

Midgley, S., & Schleich, N. (2015). Dual-energy X-ray analysis using synchrotron computed tomography at 35 and 60 keV for the estimation of photon interaction coefficients describing attenuation and energy absorption. Journal of Synchrotron Radiation, 22, 807-818. doi: 10.1107/S1600577515004579

Journal - Research Article

Midgley, S., Schleich, N., Merchant, A., & Stevenson, A. (2019). CT dosimetry at the Australian Synchrotron for 25–100 keV photons and 35–160 mm-diameter biological specimens. Journal of Synchrotron Radiation, 26, 517-527. doi: 10.1107/S1600577518018015

Anjomrouz, M., Shamshad, M., Panta, R. K., Vanden Broeke, L., Schleich, N., Atharifard, A., Raja, A., Bheesette, S., Walsh, M. F., Goulter, B. P., … Bateman, C. J., Butler, A. P. H., & Butler, P. H. (2018). Beam profile assessment in spectral CT scanners. Journal of Applied Clinical Medical Physics, 19(2), 287-297. doi: 10.1002/acm2.12260

Raja, A. Y., Moghiseh, M., Bateman, C. J., de Ruiter, N., Schon, B., Schleich, N., Woodfield, T. B. F., Butler, A. P. H., & Anderson, N. G. (2018). Measuring identification and quantification errors in spectral CT material decomposition. Applied Sciences, 8(3), 467. doi: 10.3390/app8030467

Boman, E. L., Satherley, T. W. S., Schleich, N., Paterson, D. B., Greig, L., & Louwe, R. J. W. (2017). The validity of Acuros BV and TG-43 for high-dose-rate brachytherapy superficial mold treatments. Brachytherapy, 16(6), 1280-1288. doi: 10.1016/j.brachy.2017.08.010

Midgley, S., & Schleich, N. (2015). Dual-energy X-ray analysis using synchrotron computed tomography at 35 and 60 keV for the estimation of photon interaction coefficients describing attenuation and energy absorption. Journal of Synchrotron Radiation, 22, 807-818. doi: 10.1107/S1600577515004579

Rajendran, K., Walsh, M. F., de Ruiter, N. J. A., Chernoglazov, A. I., Panta, R. K., Butler, A. P. H., … Anderson, N. G., Woodfield, T. B. F., Tredinnick, S. J., … Bateman, C. J., Aamir, R., … Smithies, D. J., Mohr, J. L., … Ronaldson, J. P., … Atharifard, A., … Schleich, N., & Billinghurst, M. (2014). Reducing beam hardening effects and metal artefacts in spectral CT using Medipix3RX. Journal of Instrumentation, 9, P03015. doi: 10.1088/1748-0221/9/03/P03015

Aamir, R., Chernoglazov, A., Bateman, C. J., Butler, A. P. H., Butler, P. H., Anderson, N. G., … Panta, R. K., … Mohr, J. L., Rajendran, K., Walsh, M. F., de Ruiter, N., Gieseg, S. P., Woodfield, T., … Schleich, N., Scott, N., … Ronaldson, J. P., Cook, N. J., … Hodge, K. (2014). MARS spectral molecular imaging of lamb tissue: Data collection and image analysis. Journal of Instrumentation, 9, P02005. doi: 10.1088/1748-0221/9/02/P02005

Grasso, C., Fabre, M.-S., Collis, S. V., Castro, M. L., Field, C. S., Schleich, N., McConnell, M. J., & Herst, P. M. (2014). Pharmacological doses of daily ascorbate protect tumors from radiation damage after a single dose of radiation in an intracranial mouse glioma model. Frontiers in Oncology, 4, 356. doi: 10.3389/fonc.2014.00356

Butler, A. P. H., Butzer, J., Schleich, N., Cook, N. J., Anderson, N. G., Scott, N., de Ruiter, N., … Butler, P. H. (2011). Processing of spectral X-ray data with principal components analysis. Nuclear Instruments & Methods in Physics Research Section A, 633(Suppl. 1), S140-S142. doi: 10.1016/j.nima.2010.06.149

Zainon, R., Butler, A. P. H., Cook, N. J., Butzer, J. S., Schleich, N., de Ruiter, N., … Butler, P. H. (2010). Construction and operation of the MARS-CT scanner. Internetworking Indonesia Journal, 2(1). Retrieved from http://www.internetworkingindonesia.org/Issues/Vol2-No1-Spring2010/iij_vol2_no1_2010_zainon.pdf

Anderson, N. G., Butler, A. P., Scott, N. J. A., Cook, N. J., Butzer, J. S., Schleich, N., … de Ruiter, N., … Butler, P. H. (2010). Spectroscopic (multi-energy) CT distinguishes iodine and barium contrast material in MICE. European Radiology, 20, 2126-2134. doi: 10.1007/s00330-010-1768-9

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Conference Contribution - Published proceedings: Full paper

Schleich, N., & Herst, P. (2014). Dosimetry for treating brain tumours in mice using a gamma irradiator. Proceedings of the Combined Scientific Meeting: Imaging and Radiation in Personalised Medicine. doi: 10.1594/ranzcr2014/R-0293

Midgley, S., & Schleich, N. (2014). Dual energy X-ray analysis using synchrotron computed tomography at 35-60 keV. Combined Scientific Meeting: Imaging and Radiation in Personalised Medicine. doi: 10.1594/ranzcr2014/R-0242

Zainon, R., Butler, A. P. H., Cook, N., Butzer, J., Schleich, N., de Ruiter, N., … Butler, P. H. (2009). Construction and operation of MARS-CT scanner. Proceedings of the International Conference on Instrumentation, Control & Automation (ICA). (pp. 79-84). [Full Paper]

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Conference Contribution - Published proceedings: Abstract

Schleich, N., Midgley, S., & Herst, P. (2018). Dosimetric assessment for whole brain irradiation in mice using a gamma irradiator. Proceedings of the 18th Asia-Oceania Congress of Medical Physics (AOCMP) in conjunction with the 16th South-East Asia Congress of Medical Physics (SEACOMP). (pp. 213). Retrieved from https://www.aocmp2018.com/

Schleich, N., Smith, T., Midgley, S., & Hammer, N. (2018). Development of anatomical mouse CT phantoms using tissue embedding and plastination techniques. Proceedings of the 18th Asia-Oceania Congress of Medical Physics (AOCMP) in conjunction with the 16th South-East Asia Congress of Medical Physics (SEACOMP). (pp. 312). Retrieved from https://www.aocmp2018.com/

Atharifard, A., Bateman, C. J., Panta, R. K., Adebileje, S. A., Amma, M. R., Anderson, N., Anjomrouz, M., Asghariomabad, F., Bamford, B., … Bheesette, S., Butler, A. P. H., Butler, P. H., … Dalefield, T., de Ruiter, N. J. A., … Gieseg, S., Goulter, B. P., Gurney, S., Healy, J. L., Hilton, P. J., … Lowe, C., Marfo, E., Moghiseh, M., … Raja, A. Y., Ramyar, M., Renaud, P., Schleich, N., Searle, E., … Sheeja, J. S., … Walsh, M. F. (2018). Pulse pileup models for spectral X-ray imaging. Proceedings of the 20th International Workshop on Radiation Imaging Detectors. Retrieved from https://indico.cern.ch/event/686575

Butler, P. A. H., MARS Collaboration, including Adebileje, S. A., Anderson, N., Asghariomabad, F., Atharifard, A., Bamford, B., Bheesette, S., Butler, P. H., Dalefield, T., Damet, J., de Ruiter, N. J. A., Gieseg, S. P., Goulter, B. P., Gurney, S., Healy, J. L., Hilton, P. J., Lowe, C., Marfo, E., Moghiseh, M., Panta, R. K., Raja, A. Y., Ramyar, M., Renaud, P., Rundle, D., Schleich, N., Searle, E., Sheeja, J. S., … Walsh, M. F. (2018). First living human images from a MARS photon-counting 8-energy CT. Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference. M-14-180. Retrieved from http://www.nssmic.org/2018

Raja, A. Y., Atharifard, A., Vanden Broeke, L., Adebileje, S., Amma, M. R., Anderson, N., Anjomrouz, M., Asghariomabad, F., Bamford, B., … Bheesette, S., Butler, A. P. H., Butler, P. H., … Dalefield, T., de Ruiter, N. J. A., … Gieseg, S., Goulter, B. P., Gurney, S., Healy, J. L., Hilton, P., … Lowe, C., … Marfo, E., Moghiseh, M., … Panta, R. K., … Ramyar, M., Renaud, P., Schleich, N., Searle, E., … Leary, C. (2018). MARS spectral CT imaging using Medipix3RX. Proceedings of the 20th International Workshop on Radiation Imaging Detectors. Retrieved from https://indico.cern.ch/event/686575

Schleich, N., Midgley, S., & Anjomrouz, M. (2018). A cryogenic mouse holder system for synchrotron CT. Australasian Physical & Engineering Sciences in Medicine, 41(14), (pp. 279). doi: 10.1007/s13246-017-0614-7

Asghariomabad, F., Ortega-Gil, A., de Ruiter, N. J. A., Raja, A. Y., Butler, P. A. H., Butler, P. H., on behalf of MARS Collaboration, including Adebileje, S. A., Anderson, N., Atharifard, A., Bamford, B., Bheesette, S., Dalefield, T., Gieseg, S. P., Goulter, B. P., Gurney, S., Healy, J. L., Damet, J., Hilton, P. J., Lowe, C., Marfo, E., Moghiseh, M., Panta, R. K., Ramyar, M., Renaud, P., Schleich, N., Searle, E., Sheeja, J. S., … Walsh, M. F. (2018). Intrinsic respiratory gating for MARS imaging. Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference. M-07-179. Retrieved from http://www.nssmic.org/2018

Searle, E., and the MARS Collaboration, including Adebileje, S. A., Anderson, N., Asghariomabad, F., Atharifard, A., Bamford, B., Bheesette, S., Butler, A. P. H., Butler, P. H., Dalefield, T., de Ruiter, N. J. A., Gieseg, S. P., Goulter, B. P., Gurney, S., Healy, J. L., Hilton, P. J., Lowe, C., Marfo, E., Moghiseh, M., Panta, R. K., Raja, A. Y., Ramyar, M., Renaud, P., Schleich, N., Sheeja, J. S., … Walsh, M. F. (2018). Distinguishing iron and calcium using MARS spectral CT. Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference. M-07-182. Retrieved from http://www.nssmic.org/2018

Moghiseh, M., Kumar, D., Lewis, J., The MARS Collaboration, including Adebileje, S. A., Anderson, N., Asghariomabad, F., Atharifard, A., Bamford, B., Bheesette, S., Butler, A. P. H., Butler, P. H., Dalefield, T., de Ruiter, N. J. A., Gieseg, S. P., Gurney, S., Healy, J. L., Hilton, P. J., Lowe, C., Marfo, E., Panta, R. K., Raja, A. Y., Ramyar, M., Renaud, P., Schleich, N., Searle, E., Sheeja, J. S., … Walsh, M. F. (2018). Cancer imaging with nanoparticles using MARS spectral scanner. Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference. M-16-03. Retrieved from http://www.nssmic.org/2018

Vanden Broeke, L., Bateman, C. J., Kolanoski, H., Adebileje, S. A., Amma, M. R., Anderson, N., Anjomrouz, M., Asghariomabad, F., Atharifard, A., Bamford, B., … Bheesette, S., Butler, A. P. H., Butler, P. H., … Dalefield, T., de Ruiter, N. J. A., … Gieseg, S., Goulter, B. P., Gurney, S., Healy, J. L., Hilton, P. J., … Lowe, C., … Marfo, E., Moghiseh, M., … Panta, R. K., … Raja, A. Y., Ramyar, M., Renaud, P., Schleich, N., Searle, E., … Sheeja, J. S., … Walsh, M. F. (2018). Calibrating MARS Cameras using X-ray Fluorescence. Proceedings of the 20th International Workshop on Radiation Imaging Detectors. Retrieved from https://indico.cern.ch/event/686575

Marfo, E., Carbonez, P., Damet, J., Lowe, C., Anderson, N. G., Schleich, N., Raja, A., & Butler, A. P. H. (2018). In-vivo dosimetry with the small animal MARS multi-energy CT. Australasian Physical & Engineering Sciences in Medicine, 41(1), (pp. 321). doi: 10.1007/s13246-017-0614-7

Lowe, C. D., Ortega-Gil, A., on behalf of MARS Collaboration, including Adebileje, S. A., Anderson, N., Asghariomabad, F., Atharifard, A., Bamford, B., Bheesette, S., Butler, A. P. H., Butler, P. H., Dalefield, T., de Ruiter, N. J. A., Gieseg, S. P., Goulter, B. P., Gurney, S., Healy, J. L., Hilton, P. J., Marfo, E., Moghiseh, M., Panta, R. K., Raja, A. Y., Ramyar, M., Renaud, P., Schleich, N., Searle, E., Sheeja, J. S., … Walsh, M. F. (2018). MARS pulmonary spectral molecular imaging: Potential for locating tuberculosis involvement. Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference. M-14-168. Retrieved from http://www.nssmic.org/2018

Schleich, N., Aamir, R., Midgley, S. M., Bell, S., Anderson, N., & Butler, A. (2016). Development of a quality control program for spectral micro CT imaging. Australasian Physical & Engineering Sciences in Medicine, 39(1), (pp. 273). doi: 10.1007/s13246-015-0410-1

Anjomrouz, M., Shamshad, M., Smithies, D., Largeau, A., Vandon Broeke, L., Panta, R. K., Aamir, R., Atharifard, A., … Bheesette, S., de Ruiter, N., … Bateman, C. J., … Schleich, N. (2016). Beam profile assessment in MARS spectral CT. Proceedings of the Nuclear Science Symposium/Medical Imaging Conference (NIS/MIC) Conference. IEEE. Retrieved from http://2016.nss-mic.org/

Schleich, N., & Herst, P. (2016). Dosimetric assessment for whole brain irradiation in mice using a gamma irradiator. Australasian Physical & Engineering Sciences in Medicine, 39(1), (pp. 272-273). doi: 10.1007/s13246-015-0410-1

Midgley, S. M., & Schleich, N. (2016). Dosimetry and pre-processing corrections for synchrotron computed tomography. Australasian Physical & Engineering Sciences in Medicine, 39(4), (pp. 1074). doi: 10.1007/s13246-016-0494-2

Midgley, S. M., Schleich, N., & Stevenson, A. W. (2016). Dual energy X-ray analysis using synchrotron computed tomography at 30-100 keV. Australasian Physical & Engineering Sciences in Medicine, 39(1), (pp. 320). doi: 10.1007/s13246-015-0410-1

Schleich, N., Aamir, R., Midgley, S. M., Chen, M., Anderson, N., & Butler, A. (2016). An imaging quality control program for Spectral micro-CT. Australasian Physical & Engineering Sciences in Medicine, 39(4), (pp. 1055-1056). doi: 10.1007/s13246-016-0494-2

Boman, E. L., Satherley, T. W. S., Schleich, N., Paterson, D., Louwe, R. J. W., & Greig, L. (2016). Comparison of TG-43 and AcurosTM BV for HDR surface moulds. Australasian Physical & Engineering Sciences in Medicine, 39(4), (pp. 1112-1113). doi: 10.1007/s13246-016-0494-2

Schleich, N., & Herst, P. (2015). Whole brain irradiation of mice using a gamma irradiator. Australasian Physical & Engineering Sciences in Medicine, 38(1), (pp. 177-178). doi: 10.1007/s13246-014-0324-3

Day, R., Steer, B., Aguas, V., Donaldson, J., Ramadaan, I., Satherley, T., Schleich, N., … Greig, L. (2015). Implementation of the Sun Nuclear ATLAS™ database for the management of QC data at the Wellington Blood and Cancer Centre. Australasian Physical & Engineering Sciences in Medicine, 38(1), (pp. 180). doi: 10.1007/s13246-014-0324-3

Midgley, S., & Schleich, N. (2014). Dual energy X-ray analysis using synchrotron computed tomography at 35—60 keV. Journal of Medical Imaging & Radiation Oncology, 58(Suppl. 1), (pp. 287). doi: 10.1002/jmrs.74

Schleich, N., Bell, S., Midgley, S., Aamir, R., Mohr, J., Healy, J., Rajendran, K., Butler, A., Anderson, N., & Butler, P. (2014). Spectral CT imaging: A non-invasive technique for studying composition and function of tissues. Journal of Medical Imaging & Radiation Oncology, 58(Suppl. 1), (pp. 125). doi: 10.1002/jmrs.72

Day, R., Steer, B., Aguas, V., Donaldson, J., Ramadaan, I., Satherley, T., Schleich, N., … Greig, L. (2014). Implementation of the Sun Nuclear Atlas ™ database for the management of the QC data at the Wellington Blood and Cancer Centre. Proceedings of the Annual Conference of the New Zealand Branch of the Australasian College of Physical Scientists and Engineers in Medicine (NZPEM). (pp. 30). Retrieved from http://nzpem.org.nz/wordpress/?page_id=11

Midgley, S., & Schleich, N. (2014). Dual energy X-ray analysis using synchrotron computed tomography at 35—60 keV. Proceedings of the Australian Synchrotron User Meeting. (pp. 17-18). Retrieved from https://events.synchrotron.org.au/event/3/

Schleich, N., & Herst, P. (2014). Dosimetry for treating brain tumours in mice using a gamma irradiator. Journal of Medical Imaging & Radiation Oncology, 58(Suppl. 1), (pp. 310). doi: 10.1002/jmrs.74

Schleich, N., & Herst, P. (2014). Whole brain irradiation of mice using a gamma irradiator. Proceedings of the Annual Conference of the New Zealand Branch of the Australasian College of Physical Scientists and Engineers in Medicine (NZPEM). (pp. 26). Retrieved from http://nzpem.org.nz/wordpress/?page_id=11

McConnell, M., Grasso, C., Fabre, M.-S., Collis, S., Castro, L., Schleich, N., & Herst, P. (2014). Repeated pharmacological doses of ascorbate protect tumors from radiation damage after an intracranial mouse glioma model. Neuro-Oncology, 16(Suppl. 5), (pp. 88). doi: 10.1093/neuonc/nou255

Schleich, N., & Currie, B. (2013). Guidelines for total scalp irradiation. Australasian Physical & Engineering Sciences in Medicine, 36(1), (pp. 101-102). doi: 10.1007/s13246-012-0168-7

Girst, S., Schleich, N., Cook, N., Zeller, H., Butler, A., & Butler, P. (2010). Radiation dose in the 3D spectroscopic MARS scanner. Australasian Physical & Engineering Sciences in Medicine, 33(1), (pp. 114). doi: 10.1007/s13246-010-0012-x

Butler, A., Cook, N., Schleich, N., Butzer, J., Bones, P., Anderson, N., & Butler, P. (2009). Processing of spectral X-ray data using principal components analysis. Proceedings of the 11th International Workshop on Radiation Imaging Detectors (iWoRiD). Retrieved from http://www.iworid2009.cz/abstract_export.php?id=15

Anderson, N. G., Butler, A. P., Scott, N., Cook, N. J., Butzer, J., Schleich, N., & Firsching, M. (2009). Colour CT X-ray spectroscopic images of mice using Medipix-2 detector. European Radiology. 19(Suppl. 1), (pp. S228). [Abstract]

Butzer, J. S., Butler, A. P., Butler, P. H., Cook, N. J., Schleich, N., Firsching, M., Scott, N., Anderson, N., … Selkirk, J. (2008). Spectroscopic contrast agent imaging with the Medipix CT-scanner "MARS". Australasian Physical & Engineering Sciences in Medicine, 31(4), (pp. 472-473). [Abstract]

Schleich, N., Butler, A., Cook, N., Ross, F., Butzer, J., van Leeuwen, D., … Butler, P. (2008). Calibration and operation of the 3D spectroscopic ″MARS″ scanner. Australasian Physical & Engineering Sciences in Medicine. 31(4), (pp. 458). [Abstract]

Selkirk, J., Schleich, N., Cook, N., Butzer, J., Butler, A., & Butler, P. (2008). Energy calibration of the Medipix-2 Quad MXR detector. Australasian Physical & Engineering Sciences in Medicine. 31(4), (pp. 443). [Abstract]

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Conference Contribution - Poster Presentation (not in published proceedings)

Bateman, C. J., Panta, R. K., Mohr, J., de Ruiter, N., Aamir, R., Butler, A., … Schleich, N., Gieseg, S., … Hagemeyer, C. (2014, March). Material discrimination with MARS. Poster session presented at the 6th HOPE Meeting with Nobel Laureates, Tokyo, Japan.

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