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GENE222 Genes, Chromosomes and Populations

Eukaryote genomes and genome evolution; phylogenetics; cytogenetics and chromosomes; extensions of Mendelian genetics; genetic mapping in eukaryotes; genes in populations; quantitative genetics.

GENE 222 gives a broad coverage of all of the concepts that are central to modern eukaryote genetics including human genetics. As such it is directly relevant for students with an interest in any of the biological or biomedical sciences. The different parts of the paper are linked by a common theme of genetic analysis and the use of specific examples to illustrate general principles. The lecture course is complemented by a laboratory course that gives hands-on experience of many of the methods that are used in genetic analysis of eukaryotes.

Paper title Genes, Chromosomes and Populations
Paper code GENE222
Subject Genetics
EFTS 0.1500
Points 18 points
Teaching period Second Semester
Domestic Tuition Fees (NZD) $1,018.05
International Tuition Fees (NZD) $4,500.00

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Prerequisite
CELS 191 and 54 further points
Recommended Preparation
GENE 221 and BIOC 221
Schedule C
Science
Paper Structure
The lecture course is divided into seven blocks:
  • Eukaryote genomes and genome evolution
  • Phylogenetics
  • Cytogenetics and chromosomes
  • Extensions of Mendelian genetics
  • Genetic mapping in eukaryotes
  • Genes in populations
  • Quantitative genetics
The lecture course is complemented by a laboratory course, which provides training in data analysis and relevant genetic methods, including Mendelian genetics and linkage, cytogenetics, working with Drosophila, genomics, population genetics and quantitative genetics.
Teaching Arrangements
There are six weeks of laboratory classes, in three 2-week blocks, and students are assigned to one of two lab streams.
Textbooks
Recommended:
Introduction to Genetic Analysis (Griffiths, Wessler, Lewontin, Gelbart, Suzukin and Miller), 10th Edition.
The 9th Edition of this book is also satisfactory if you have access to a copy.
Course outline
View the information sheet for GENE 222
Graduate Attributes Emphasised
Global perspective, Interdisciplinary perspective, Scholarship, Critical thinking, Self-motivation, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
The broad objectives of GENE 222 are to understand:
  • Genomic variation within and between species
  • How to construct and interpret phylogenetic trees
  • The origins and diagnostic features of karyotypic variation
  • The extensions of Mendelian genetics
  • How to test alternative genetic hypotheses
  • How to map monogenic and complex disease genes
  • How evolution is explained by principles of variation, heredity and selection
  • Quantitative traits and the norm of reaction
  • Heritability, QTLs and their uses
Eligibility
Appropriate for students majoring in genetics, other biological and health sciences and molecular biotechnology.
Contact
iain.lamont@otago.ac.nz
Teaching staff
Convenor: Professor Iain Lamont (Department of Biochemistry)
Other teaching staff: Professor Jon Waters (Department of Zoology), Dr Janice Lord (Department of Botany), Professor Tony Merriman (Department of Biochemistry), Dr Martyn Kennedy (Department of Pathology) and Dr Gillian Mackay (Genetics Programme)

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Timetable

Second Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
L1 Tuesday 13:00-13:50 28-34, 36-41
Wednesday 12:00-12:50 28-34, 36-41
AND
M1 Monday 09:00-09:50 28-34

Practical

Stream Days Times Weeks
Attend one stream from
P1 Friday 14:00-17:50 30-31, 34, 36, 39-40
P2 Monday 14:00-17:50 31-32, 36-37, 40-41

Eukaryote genomes and genome evolution; phylogenetics; cytogenetics and chromosomes; extensions of Mendelian genetics; genetic mapping in eukaryotes; genes in populations; quantitative genetics.

GENE 222 gives a broad coverage of all of the concepts that are central to modern eukaryote genetics including human genetics. As such it is directly relevant for students with an interest in any of the biological or biomedical sciences. The different parts of the paper are linked by a common theme of genetic analysis and the use of specific examples to illustrate general principles. The lecture course is complemented by a laboratory course that gives hands-on experience of many of the methods that are used in genetic analysis of eukaryotes.

Paper title Genes, Chromosomes and Populations
Paper code GENE222
Subject Genetics
EFTS 0.1500
Points 18 points
Teaching period Second Semester
Domestic Tuition Fees (NZD) $1,038.45
International Tuition Fees (NZD) $4,680.00

^ Top of page

Prerequisite
CELS 191 and 90 further points
Recommended Preparation
GENE 221 and BIOC 221
Schedule C
Science
Eligibility
Appropriate for students majoring in genetics, other biological and health sciences and molecular biotechnology.
Contact
iain.lamont@otago.ac.nz
Teaching staff
Convenor: Professor Iain Lamont (Department of Biochemistry)
Other teaching staff: Professor Jon Waters (Department of Zoology), Dr Janice Lord (Department of Botany), Professor Tony Merriman (Department of Biochemistry), Dr Martyn Kennedy (Department of Pathology) and Dr Gillian Mackay (Genetics Programme)
Paper Structure
The lecture course is divided into seven blocks:
  • Eukaryote genomes and genome evolution
  • Phylogenetics
  • Cytogenetics and chromosomes
  • Extensions of Mendelian genetics
  • Genetic mapping in eukaryotes
  • Genes in populations
  • Quantitative genetics
The lecture course is complemented by a laboratory course, which provides training in data analysis and relevant genetic methods, including Mendelian genetics and linkage, cytogenetics, working with Drosophila, genomics, population genetics and quantitative genetics.
Teaching Arrangements
There are six weeks of laboratory classes, in three 2-week blocks, and students are assigned to one of two lab streams.
Textbooks
Recommended:
Introduction to Genetic Analysis (Griffiths, Wessler, Lewontin, Gelbart, Suzukin and Miller), 10th Edition.
The 9th Edition of this book is also satisfactory if you have access to a copy.
Course outline
View the information sheet for GENE 222
Graduate Attributes Emphasised
Global perspective, Interdisciplinary perspective, Scholarship, Critical thinking, Self-motivation, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
The broad objectives of GENE 222 are to understand:
  • Genomic variation within and between species
  • How to construct and interpret phylogenetic trees
  • The origins and diagnostic features of karyotypic variation
  • The extensions of Mendelian genetics
  • How to test alternative genetic hypotheses
  • How to map monogenic and complex disease genes
  • How evolution is explained by principles of variation, heredity and selection
  • Quantitative traits and the norm of reaction
  • Heritability, QTLs and their uses

^ Top of page

Timetable

Second Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
L1 Tuesday 13:00-13:50 28-34, 36-41
Wednesday 12:00-12:50 28-34, 36-41
AND
M1 Monday 09:00-09:50 28-34

Practical

Stream Days Times Weeks
Attend one stream from
P1 Friday 14:00-17:50 30-31, 34, 36, 39-40
P2 Monday 14:00-17:50 31-32, 36-37, 40-41