Contact Details
- Phone
- +64 3 479 7840
- sally.mccormick@otago.ac.nz
University Links
- Position
- Professor
- Department
- Department of Biochemistry
- Qualifications
- BAgriSci(Hons) PhD(Lincoln)
- Research summary
- Lipoprotein metabolism and cardiovascular disease
Research
My laboratory studies the genetics, proteomics and biochemistry of molecules involved in heart disease across a range of biological systems. A major class of molecules involved in heart disease are the plasma lipoproteins. We are currently studying the regulation of lipoprotein levels and composition to identify therapeutic targets for their manipulation with a particular interest in the Lp(a) and HDL lipoproteins which have opposing risk associations with heart disease. We are also investigating the variation in lipoprotein-associated genes in families with various dyslipidaemias. More recently we have begun a programme to test the effect of antioxidant compounds on biochemical markers of heart disease in both animal and human trials.
Inaugural professorial lecture
Media
Read about the Lipoprotein(a) work (with audio) on RNZ Nationals Our Changing World.
Positions available
Enquiries about projects from prospective graduate, postgraduate or postdoctoral researchers are welcome and should be sent to sally.mccormick@otago.ac.nz
For information about scholarships for postgraduate students go to the University of Otago website postgraduate information page
Funding
Funding for my research has been provided by the the Health Research Council of New Zealand, The National Heart Foundation, Lottery Health, Otago Medical Research Foundation and the University of Otago.
Moore, M. K., Jones, G. T., McCormick, S., Williams, M. J. A., & Coffey, S. (2024). Association between lipoprotein(a), LPA genetic risk score, aortic valve disease, and subsequent major adverse cardiovascular events. European Journal of Preventive Cardiology. Advance online publication. doi: 10.1093/eurjpc/zwae100 Journal - Research Article
Siddiqui, H., Deo, N., Rutledge, M. T., Williams, M. J. A., Redpath, G. M. I., & McCormick, S. P. A. (2023). Plasminogen receptors promote lipoprotein(a) uptake by enhancing surface binding and facilitating macropinocytosis. Arteriosclerosis, Thrombosis, & Vascular Biology. Advance online publication. doi: 10.1161/atvbaha.123.319344 Journal - Research Article
Moore, M., Jones, G., McCormick, S., Williams, M., & Coffey, S. (2023). Association between lipoprotein(a), LPA genetic risk score, aortic valve disease, and subsequent major adverse cardiovascular events. Heart, Lung & Circulation, 32(Suppl. 2), P66. doi: 10.1016/j.hlc.2023.04.287 Conference Contribution - Published proceedings: Abstract
Moors, J., Krishnan, M., Sumpter, N., Takei, R., Bixley, M., Cadzow, M., Major, T. J., Phipps Green, A., Topless, R., Merriman, M., Rutledge, M., Morgan, B., … Stamp, L., Taumoepeau, M., … Wilcox, P., … McCormick, S., … Merriman, T. R., & Leask, M. (2023). A Polynesian-specific missense CETP variant alters the lipid profile. Human Genetics & Genomic Advances, 4, 100204. doi: 10.1016/j.xhgg.2023.100204 Journal - Research Article
Merriman, T., Matsuo, H., Takei, R., Leask, M., Topless, R., Shirai, Y., … Cadzow, M., … Stamp, L., … Robinson, P., … Sumpter, N., Merriman, M., Phipps-Green, A., Wei, W., McCormick, S., … Major, T. (2022). A genome-wide association analysis of 2,622,830 individuals reveals new pathogenic pathways in gout. Arthritis & Rheumatology, 74(Suppl. 9), 1678. doi: 10.1002/art.42355 Conference Contribution - Published proceedings: Abstract
2024
Journal - Research Article
Moore, M. K., Jones, G. T., McCormick, S., Williams, M. J. A., & Coffey, S. (2024). Association between lipoprotein(a), LPA genetic risk score, aortic valve disease, and subsequent major adverse cardiovascular events. European Journal of Preventive Cardiology. Advance online publication. doi: 10.1093/eurjpc/zwae100
2023
Journal - Research Article
Siddiqui, H., Deo, N., Rutledge, M. T., Williams, M. J. A., Redpath, G. M. I., & McCormick, S. P. A. (2023). Plasminogen receptors promote lipoprotein(a) uptake by enhancing surface binding and facilitating macropinocytosis. Arteriosclerosis, Thrombosis, & Vascular Biology. Advance online publication. doi: 10.1161/atvbaha.123.319344
Moors, J., Krishnan, M., Sumpter, N., Takei, R., Bixley, M., Cadzow, M., Major, T. J., Phipps Green, A., Topless, R., Merriman, M., Rutledge, M., Morgan, B., … Stamp, L., Taumoepeau, M., … Wilcox, P., … McCormick, S., … Merriman, T. R., & Leask, M. (2023). A Polynesian-specific missense CETP variant alters the lipid profile. Human Genetics & Genomic Advances, 4, 100204. doi: 10.1016/j.xhgg.2023.100204
Conference Contribution - Published proceedings: Abstract
Moore, M., Jones, G., McCormick, S., Williams, M., & Coffey, S. (2023). Association between lipoprotein(a), LPA genetic risk score, aortic valve disease, and subsequent major adverse cardiovascular events. Heart, Lung & Circulation, 32(Suppl. 2), P66. doi: 10.1016/j.hlc.2023.04.287
2022
Journal - Research Other
Siddiqui, H., Yevstigneyev, N., Madani, G., & McCormick, S. (2022). Approaches to visualising endocytosis of LDL-related lipoproteins. Biomolecules, 12, 158. doi: 10.3390/biom12020158
Conference Contribution - Published proceedings: Abstract
Merriman, T., Matsuo, H., Takei, R., Leask, M., Topless, R., Shirai, Y., … Cadzow, M., … Stamp, L., … Robinson, P., … Sumpter, N., Merriman, M., Phipps-Green, A., Wei, W., McCormick, S., … Major, T. (2022). A genome-wide association analysis of 2,622,830 individuals reveals new pathogenic pathways in gout. Arthritis & Rheumatology, 74(Suppl. 9), 1678. doi: 10.1002/art.42355
Ismail, L., Black, M., Williams, M., Coassin, S., Forer, L., Kronenberg, F., & McCormick, S. (2022). Variants in solute cation transporters 3 associate with high Lp(a) levels independent of apo(a) isoform size. Circulation, 146(Suppl. 1), 12528. doi: 10.1161/circ.146.suppl_1.13062
Ismail, L., Black, M., Cadzow, M., Merriman, T., Williams, M., & McCormick, S. (2022). Two variants are associated with high lipoprotein (a) levels independent of apolipoprotein (a) isoform size. Proceedings of the ComBio Conference. (pp. 169). Retrieved from https://combio.org.au/combio2022/
McCormick, S. P. A. (2022). Pathways of lipoprotein(a) catabolism. Pathology, 54(Suppl. 1), (pp. S5). doi: 10.1016/j.pathol.2021.12.020
Conference Contribution - Verbal presentation and other Conference outputs
Siddiqui, H., Redpath, G. M., Deo, N., & McCormick, S. P. A. (2022, August). Understanding the role of plasminogen receptors in lipoprotein(a) uptake via confocal microscopy. Verbal presentation at the Advances in Microscopy Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
2021
Conference Contribution - Published proceedings: Abstract
Siddiqui, H., Redpath, G., Deo, N., & McCormick, S. (2021). Role of plasminogen receptors in the uptake of lipoprotein(a). Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 301). Retrieved from https://www.faobmb2021.org
Platt, R., McCormick, S., Black, M., & Ismail, L. (2021). Sequencing of lipoprotein(a) null individuals to determine mutations causing phenotype. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 60). Retrieved from https://www.faobmb2021.org
Ismail, L., Black, M., Jones, G., Williams, M., & McCormick, S. (2021). Identifying functional variants associated with high lipoprotein (a) phenotypes. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 55). Retrieved from https://www.faobmb2021.org
2020
Journal - Research Article
Akhavan, S. R., Falahatkar, B., McCormick, S. P. A., & Lokman, P. M. (2020). Changes in lipid biology during ovarian development in farmed beluga sturgeon, Huso huso L. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 319, R376-R386. doi: 10.1152/ajpregu.00364.2019
Jones, G. T., Marsman, J., Bhat, B., Phillips, V. L., Chatterjee, A., Rodger, E. J., Williams, M. J. A., van Rij, A. M., & McCormick, S. P. A. (2020). DNA methylation profiling identifies a high effect genetic variant for lipoprotein(a) levels. Epigenetics, 15(9), 949-958. doi: 10.1080/15592294.2020.1739797
Kader, T., Porteous, C. M., Jones, G. T., Dickerhof, N., Narayana, V. K., Tull, D., Taraknath, S., & McCormick, S. P. A. (2020). Ribose-cysteine protects against the development of atherosclerosis in apoE-deficient mice. PLoS ONE, 15(2), e0228415. doi: 10.1371/journal.pone.0228415
Morgan, B. M., Brown, A. N., Deo, N., Harrop, T. W. R., Taiaroa, G., Mace, P. D., Wilbanks, S. M., Merriman, T. R., Williams, M. J. A., & McCormick, S. P. A. (2020). Nonsynonymous SNPs in LPA homologous to plasminogen deficiency mutants represent novel null apo(a) alleles. Journal of Lipid Research, 61, 432-444. doi: 10.1194/jlr.M094540
Conference Contribution - Published proceedings: Abstract
Siddiqui, H., Redpath, G., Deo, N., & McCormick, S. (2020). Role of plasminogen receptors in the uptake of lipoprotein(A). Proceedings of the Otago Global Health Institute (OGHI) 13th Annual Conference: Shared Humanity and Global Health. (pp. 17). Retrieved from https://events.otago.ac.nz/oghiconf2020
2019
Journal - Research Article
McCormick, S. P. A., & Schneider, W. J. (2019). Lipoprotein(a) catabolism: A case of multiple receptors. Pathology, 51(2), 155-164. doi: 10.1016/j.pathol.2018.11.003
Conference Contribution - Published proceedings: Abstract
McCormick, S., Morgan, B., Brown, A., Wilbanks, S., Mace, P., & Williams, M. (2019). Nonsynonymous variants in Lpa represent novel null apolipoprotein(a) alleles. Atherosclerosis, 287, (pp. e2-e3). doi: 10.1016/j.atherosclerosis.2019.06.007
Other Research Output
Burnett, J. R., Hooper, A. J., McCormick, S. P. A., & Hegele, R. A. (2019). Clinical utility gene card for: Tangier disease. GeneReviews. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK549920/
2018
Journal - Research Article
Rodger, E. J., Porteous, C. M., Jones, G. T., Legge, M., Kleffmann, T., & McCormick, S. P. A. (2018). Proteomic analysis of liver from lipoprotein(a) transgenic mice shows an oxidative stress and lipid export response. BioMed Research International, 2018, 4963942. doi: 10.1155/2018/4963942
Conference Contribution - Published proceedings: Abstract
McCormick, S., Porteous, C., Sharma, M., Jones, G., Legge, M., Kleffmann, T., & Rodger, E. (2018). Proteomic analysis of liver from human Lipoprotein(a) transgenic mice shows an oxidative stress and lipid export response. Atherosclerosis Supplements, 32, (pp. 4). doi: 10.1016/j.atherosclerosissup.2018.04.013
Conference Contribution - Poster Presentation (not in published proceedings)
Dean, C. H., & McCormick, S. P. A. (2018, August). Standardising purification and defining receptors for lipoprotein(a). Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2017
Journal - Research Article
Sharma, M., Redpath, G. M., Williams, M. J. A., & McCormick, S. P. A. (2017). Recycling of apolipoprotein(a) after PlgRKT-mediated endocytosis of lipoprotein(a). Circulation Research, 120(7), 1091-1102. doi: 10.1161/circresaha.116.310272
Journal - Research Other
Hooper, A. J., McCormick, S. P. A., Hegele, R. A., & Burnett, J. R. (2017). Clinical utility gene card for: Tangier disease. European Journal of Human Genetics, 25, e1-e3. doi: 10.1038/ejhg.2017.72
Conference Contribution - Published proceedings: Abstract
Major, T. J., Cadzow, M. J., Merriman, M. E., Phipps-Green, A. J., Topless, R. K. G., Abhishek, A., … McCormick, S. P. A., … Walker, R. J., … Stamp, L. K., & Merriman, T. R. (2017). Genome-wide association study of gout in 111,098 people of european ancestry. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 547. Retrieved from http://gen2017.w.events4you.currinda.com
Munir, J., Kleffmann, T., & McCormick, S. (2017). Proteomic analysis of 4-phenylbutyrate treated HepG2 cells stably expressing ATP-binding Cassette Transporter A1 (ABCA1) mutants. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 60). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html
Merriman, T. R., Cadzow, M., Merriman, M., Phipps-Green, A., Topless, R., Abhishek, A., … McCormick, S., … Walker, R., … Stamp, L., & Flynn, T. (2017). A genome-wide association study of gout in people of European ancestry. Annals of the Rheumatic Diseases, 76(Suppl. 2), (pp. 383). doi: 10.1136/annrheumdis-2017-eular.5634
Merriman, T. R., Cadzow, M., Merriman, M. E., Phipps-Green, A., Topless, R., Abhishek, A., … McCormick, S., … Walker, R., … Stamp, L. K., & Major, T. (2017). A genome-wide association study of gout in people of European ancestry. Arthritis & Rheumatology, 69(Suppl. 10), 1104. doi: 10.1002/art.40321
Morgan, B., & McCormick, S. (2017). Protein modeling of nonsynonymous SNPs in apolipoprotein(a). New Zealand Medical Journal, 130(1452), (pp. 79). Retrieved from https://www.nzma.org.nz/journal
Conference Contribution - Poster Presentation (not in published proceedings)
Munir, J., Kleffmann, T., & McCormick, S. P. (2017, September). Proteomic analysis of 4-phenylbutyrate treated HepG2 cells stably expressing ATP-binding cassette transporter A1 (ABCA1) mutants. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2016
Journal - Research Article
Rasheed, H., Phipps-Green, A. J., Topless, R., Smith, M. D., Hill, C., Lester, S., … van Rij, A., Jones, G. T., McCormick, S. P., Harrison, A. A., Stamp, L. K., … Merriman, T. R. (2016). Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout. Rheumatology, 55(8), 1421-1430. doi: 10.1093/rheumatology/kew057
Sharma, M., Tuaine, J., McLaren, B., Waters, D. L., Black, K., Jones, L. M., & McCormick, S. P. A. (2016). Chemotherapy agents alter plasma lipids in breast cancer patients and show differential effects on lipid metabolism genes in liver cells. PLoS ONE, 11(1), e0148049. doi: 10.1371/journal.pone.0148049
Damsteegt, E. L., Ozaki, Y., McCormick, S. P. A., & Lokman, P. M. (2016). Triacylglyceride physiology in the shortfinned eel, Anguilla australis: The effects of androgen. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 310, R422-R431. doi: 10.1152/ajpregu.00149.2015
Conference Contribution - Published proceedings: Abstract
Sharma, M., Redpath, G., & McCormick, S. (2016). Calcium dependent endocytosis and recycling of lipoprotein(a) in HepG2 cells. Atherosclerosis, 252, (pp. e244). doi: 10.1016/j.atherosclerosis.2016.07.038
Conference Contribution - Verbal presentation and other Conference outputs
Taiaroa, G., Brown, A. N., & McCormick, S. P. (2016, August-September). The dynamic and hypervariable nature of LPA. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
Sharma, M., Redpath, G., Williams, M. J. A., & McCormick, S. P. A. (2016, August-September). Recycling of apolipoprotein(a) after PlgRKT-mediated endocytosis of lipoprotein(a). Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
McCormick, S. (2016, August-September). Ribose-cysteine increases glutathione-based antioxidant status and reduces atherosclerosis in apoE-deficient mice. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
Other Research Output
McCormick, S. (2016, June). New connections between old lipids. University of Otago, Dunedin, New Zealand. [Inaugural Professorial Lecture].
2015
Journal - Research Article
Ooi, E. M., Watts, G. F., Chan, D. C., Pang, J., Tenneti, V. S., Hamilton, S. J., McCormick, S. P., … Barrett, P. H. R. (2015). Effects of extended-release niacin on the postprandial metabolism of Lp(a) and ApoB-100-containing lipoproteins in statin-treated men with type 2 diabetes mellitus. Arteriosclerosis, Thrombosis, & Vascular Biology, 35, 2686-2693. doi: 10.1161/atvbaha.115.306136
Sharma, M., Von Zychlinski-Kleffmann, A., Porteous, C. M., Jones, G. T., Williams, M. J. A., & McCormick, S. P. A. (2015). Lipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipids. Journal of Lipid Research, 56, 1318-1328. doi: 10.1194/jlr.M056150
Damsteegt, E. L., Falahatimarvast, A., McCormick, S. P. A., & Lokman, P. M. (2015). Triacylglyceride physiology in the short-finned eel, Anguilla australis: Changes throughout early oogenesis. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 308(11), R935-R944. doi: 10.1152/ajpregu.00436.2014
Conference Contribution - Poster Presentation (not in published proceedings)
Rasheed, H., Phipps-Green, A. J., Topless, R., Smith, M., Hill, C., Lester, S., … van Rij, A., Jones, G. T., McCormick, S. P., Harrison, A. A., Stamp, L. K., … Merriman, T. R. (2015, August-September). Replication of association of the apolipoprotein A1-C3-A4 cluster with gout risk: Evidence for a causal role in gout. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2014
Journal - Research Article
Rasheed, H., Hsu, A., Dalbeth, N., Stamp, L. K., McCormick, S., & Merriman, T. R. (2014). The relationship of apolipoprotein B and very low density lipoprotein triglyceride with hyperuricemia and gout. Arthritis Research & Therapy, 16(6), 495.
Kader, T., Porteous, C. M., Williams, M. J. A., Gieseg, S. P., & McCormick, S. P. A. (2014). Ribose-cysteine increases glutathione-based antioxidant status and reduces LDL in human lipoprotein(a) mice. Atherosclerosis, 237(2), 725-733. doi: 10.1016/j.atherosclerosis.2014.10.101
von Zychilinski, A., Williams, M., McCormick, S., & Kleffmann, T. (2014). Absolute quantification of apolipoproteins and associated proteins on human plasma lipoproteins. Journal of Proteomics, 106, 181-190. doi: 10.1016/j.jprot.2014.04.030
Conference Contribution - Published proceedings: Abstract
Rasheed, H., Hsu, A., Dalbeth, N., Stamp, L. K., McCormick, S., & Merriman, T. R. (2014). Association analysis of apolipoprotein B and very low-density lipoprotein with hyperuricemia and gout. Arthritis & Rheumatology, 66(10, Suppl.), (pp. S1295-S1296). doi: 10.1002/art.38914
Kader, T., Porteous, C., Gieseg, S., & McCormick, S. (2014). The effect of riboceine on glutathione, glutathione peroxidase and plasma lipid levels in Lp(a) mice. New Zealand Medical Journal, 127(1395). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Verbal presentation and other Conference outputs
Rasheed, H., Hsu, A., Dalbeth, N., Stamp, L., McCormick, S., & Merriman, T. (2014, August). Association analysis of apolipoprotein B and very low-density lipoprotein with gout in the presence of hyperuricemia. Verbal presentation at the New Zealand Rheumatology Association Annual Scientific Meeting, Dunedin, New Zealand.
2013
Journal - Research Article
Sorrenson, B., Suetani, R. J., Williams, M. J. A., Bickley, V. M., George, P. M., Jones, G. T., & McCormick, S. P. A. (2013). Functional rescue of mutant ABCA1 proteins by sodium 4-phenylbutyrate. Journal of Lipid Research, 54, 55-62. doi: 10.1194/jlr.M027193
Conference Contribution - Published proceedings: Abstract
Kader, T., Porteous, C., Geiseg, S., & McCormick, S. (2013). The effect of riboceine on glutathione and plasma cholesterol levels in Lp(a) mice. New Zealand Medical Journal, 126(1386). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Poster Presentation (not in published proceedings)
Sharma, M., von Zychlinski-Kleffmann, A., & McCormick, S. P. A. (2013, August). Lp(a) promotes upregulation of the ABCA1 pathway in hepatocytes. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Kader, T., Porteous, C., & McCormick, S. P. A. (2013, August). The effect of cysteine analogues on lipoprotein(a). Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
von Zychilinski, A., Williams, M., Kleffmann, T., & McCormick, S. (2013, August). What is really on our lipoproteins? Quantitative information about the protein makeup of the major lipoprotein classes. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2012
Journal - Research Article
Kardys, I., Oemrawsingh, R. M., Kay, P., Jones, G. T., McCormick, S. P. A., Daemen, J., … Serruys, P. (2012). Lipoprotein(a), interleukin-10, C-reactive protein, and 8-year outcome after percutaneous coronary intervention. Clinical Cardiology, 35(8), 482-489. doi: 10.1002/clc.21988
Rodger, E. J., Suetani, R. J., Jones, G. T., Kleffmann, T., Carne, A., Legge, M., & McCormick, S. P. A. (2012). Proteomic analysis of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis. PLoS ONE, 7(1), e30383. doi: 10.1371/journal.pone.0030383
Conference Contribution - Published proceedings: Abstract
McCormick, S. P. A. (2012). Proteomic analysis of aortae from human lipoprotein(a) transgenic mice. Heart, Lung & Circulation, 21(12). doi: 10.1016/j.hlc.2012.08.012
Morley, T. D., Redpath, G. M. I., Kleffmann, T., von Zychilinski, A., Williams, M. J. A., & McCormick, S. P. A. (2012). Characterisation of the low density lipoprotein receptor binding properties of lipoproteins from a familial hypoalphalipoproteinemia subject. Proceedings of the Medical Sciences Congress (MedSci). (pp. 68). Retrieved from http://www.medscinz.co.nz/QRW2012%20MedSci%20Abstracts.pdf
2011
Journal - Research Article
von Zychlinski, A., Kleffmann, T., Williams, M. J. A., & McCormick, S. P. (2011). Proteomics of Lipoprotein(a) identifies a protein complement associated with response to wounding. Journal of Proteomics, 74, 2881-2891. doi: 10.1016/j.jprot.2011.07.008
Suetani, R. J., Sorrenson, B., Tyndall, J. D. A., Williams, M. J. A., & McCormick, S. P. A. (2011). Homology modeling and functional testing of an ABCA1 mutation causing Tangier disease. Atherosclerosis, 218(2), 404-410. doi: 10.1016/j.atherosclerosis.2011.06.019
Sorrenson, B., Suetani, R. J., Bickley, V. M., George, P. M., Williams, M. J. A., Scott, R. S., & McCormick, S. P. A. (2011). An ABCA1 truncation shows no dominant negative effect in a familial hypoalphalipoproteinemia pedigree with three ABCA1 mutations. Biochemical & Biophysical Research Communications, 409(3), 400-405. doi: 10.1016/j.bbrc.2011.05.006
Roberts, R. L., van Rij, A. M., Phillips, L. V., Young, S., McCormick, S. P. A., Merriman, T. R., & Jones, G. T. (2011). Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms. Atherosclerosis, 218(1), 123-126. doi: 10.1016/j.atherosclerosis.2011.04.043
Dickerhof, N., Kleffmann, T., Jack, R., & McCormick, S. (2011). Bacitracin inhibits the reductive activity of protein disulfide isomerase by disulfide bond formation with free cysteines in the substrate-binding domain. FEBS Journal, 278(12), 2034-2043. doi: 10.1111/j.1742-4658.2011.08119.x
Conference Contribution - Published proceedings: Abstract
von Zychlinski, A., McCormick, S., & Kleffmann, T. (2011). The proteome of human Lp(a) points to a role in wound healing. Proceedings of the 10th Human Proteome World Congress (HUPO). Retrieved from https://b-com.mci-group.com/Abstract/Statistics/AbstractStatisticsViewPage.aspx?AbstractID=71070
Conference Contribution - Poster Presentation (not in published proceedings)
Hsu, A., Dalbeth, N., Gow, P., Harrison, A. A., Highton, J., Jones, P. B. B., Stamp, L. K., Merriman, T. R., & McCormick, S. P. (2011, September). Lipoprotein properties and type IV hyperlipoproteinemia (TIVH) in Māori and Pacific people with gout. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Suetani, R., Sorrenson, B., Tyndall, J., Williams, M., & McCormick, S. (2011, September). Homology modelling and functional testing of ABCA1 mutations. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Dickerhof, N., Kleffmann, T., Jack, R., & McCormick, S. (2011, September). Bacitracin inhibits the reductive activity of protein disulfide isomerase by forming a disulfide bond with free cysteines in the substrate binding domain. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
von Zychilinski, A., Kleffmann, T., & McCormick, S. (2011, September). Proteomics of lipoprotein(a). Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2010
Journal - Research Article
Pedersen, T. X., McCormick, S. P., Tsimikas, S., Bro, S., & Nielsen, L. B. (2010). Lipoprotein(a) accelerates atherosclerosis in uremic mice. Journal of Lipid Research, 51(10), 2967-2975. doi: 10.1194/jlr.M006742
Brace, R. J., Sorrenson, B., Sviridov, D., & McCormick, S. P. A. (2010). A gel-based method for purification of apolipoprotein A-I from small volumes of plasma. Journal of Lipid Research, 51, 3370-3376. doi: 10.1194/jlr.D008300
Conference Contribution - Published proceedings: Abstract
Rodger, E., Jones, G., Kleffmann, T., Carne, A., & McCormick, S. (2010). Proteomic analysis of aortae from human lipoprotein(a) transgenic mice indicates an altered metabolic and redox response that precedes atherosclerosis. Proceedings of the Human Proteome World Congress (HUPO): Launch of the Human Proteome Project. (pp. 143). Retrieved from http://www.hupo.org/congress/congress_2010/downloads/HUPO2010%20World%20Congress%20Abstract%20Book.pdf
Pedersen, T. X., McCormick, S. P., Tsimikas, S., Bro, S., & Nielsen, L. B. (2010). Lipoprotein(a) accelerates atherosclerosis in uremic mice. Atherosclerosis Supplements. 11(2), (pp. 72). [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Redpath, G., & McCormick, S. (2010, September). Characterisation and analysis of low density lipoprotein from familial hypoalphalipoproteinemia subjects. Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand.
2009
Journal - Research Article
Wang, Y.-T., von Zychlinski, A., & McCormick, S. P. A. (2009). Dimyristoylphosphotidylcholine induces conformational changes in apoB that lowers lipoprotein(a). Journal of Lipid Research, 50(5), 846-853. doi: 10.1194/jlr.M800428-JLR200
Journal - Research Other
Jones, G. T., Deng, M., Hammond-Tooke, G. D., McCormick, S. P. A., & van Rij, A. M. (2009). Increased plasma lipoprotein(a) found in large-artery atherosclerotic, but not small-artery occlusive, stroke [Letter to the editor]. Clinical Chemistry, 55(10), 1888-1890. doi: 10.1373/clinchem.2009.126771
Conference Contribution - Published proceedings: Abstract
Brace, R., Williams, M., Sviridov, D., Mukhamedova, N., & McCormick, S. (2009). Influence of ABCA1 promoter haplotypes on a novel R1068H mutation. Atherosclerosis Supplements. 10(2), (pp. e452). [Abstract]
Rodger, E. J., Jones, G. T., Kleffmann, T., Carne, A., & McCormick, S. P. A. (2009). Proteomic characterisation of aortae from human lipoprotein(a) transgenic mice indicates altered metabolic flux and redox state. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Sorrenson, B., Jones, G. T., Williams, M. J., Bickley, V. M., Scott, R. S., George, P. M., & McCormick, S. P. A. (2009). Functional studies of novel ABCA1 mutations associated with low HDL-cholesterol levels. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Brace, R. J., Williams, M. J., Tyndall, J. D. A., Sviridov, D., Mukhamedova, N., Albrecht, C., & McCormick, S. P. A. (2009). Characterisation of a novel Tangier disease ABCA1 protein. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Dickerhof, N., von Zychlinski-Kleffmann, A., Kleffmann, T., Jack, R., & McCormick, S. (2009). Using an old antibiotic to lower lipoprotein(a). Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Sorrenson, B., Jones, G. T., Williams, M. J., Bickley, V. M., Scott, R. S., George, P. M., & McCormick, S. P. A. (2009, September). Functional studies of novel ABCA1 mutations associated with low HDL-cholesterol levels. Poster session presented at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand.
2008
Journal - Research Article
Murphy, A. J., Woollard, K. J., Hoang, A., Mukhamedova, N., Stirzaker, R. A., McCormick, S. P. A., … Chin-Dusting, J. (2008). High-density lipoprotein reduces the human monocyte inflammatory response. Arteriosclerosis, Thrombosis, & Vascular Biology, 28(11), 2071-2077. doi: 10.1161/ATVBAHA.108.168690
Slatter, T. L., Jones, G. T., Williams, M. J. A., van Rij, A. M., & McCormick, S. P. A. (2008). Novel rare mutations and promoter haplotypes in ABCA1 contribute to low-HDL-C levels. Clinical Genetics, 73, 179-184. doi: 10.1111/j.1399-0004.2007.00940.x
Conference Contribution - Poster Presentation (not in published proceedings)
Sorrenson, B., Homer, V. M., Scott, R. S., George, P. M., & McCormick, S. P. A. (2008, November-December). Two different ABCA1 mutations in a family with familial hypoalphalipoproteinemia. Poster session presented at the New Zealand Institute of Chemistry, New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Biologists Combined Conference, Dunedin, New Zealand.
Wyatt, A. K., Merriman, T. R., Jones, G. T., van Rij, A., & McCormick, S. P. A. (2008, November-December). Identification and analysis of null lipoprotein(a) genotypes. Poster session presented at the New Zealand Institute of Chemistry, New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Biologists Combined Conference, Dunedin, New Zealand.
Rodger, E. J., Revell, A. F., Jones, G. T., Kleffmann, T., & McCormick, S. P. A. (2008, November-December). Proteomic analysis of livers from mice with an atherogenic lipoprotein profile. Poster session presented at the New Zealand Institute of Chemistry, New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Biologists Combined Conference, Dunedin, New Zealand.
Brace, R. J., Williams, M. J., Sviridov, D., Mukhamedova, N., & McCormick, S. P. A. (2008, November-December). Influence of ABCA1 promoter SNPS on promoter activity in cultured cells. Poster session presented at the New Zealand Institute of Chemistry, New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Biologists Combined Conference, Dunedin, New Zealand.
2007
Journal - Research Article
Jones, G. T., van Rij, A. M., Cole, J., Williams, M. J. A., Bateman, E. H., Marcovina, S. M., Deng, M., & McCormick, S. P. A. (2007). Plasma lipoprotein(a) indicates risk for 4 distinct forms of vascular disease. Clinical Chemistry, 53(4), 679-685.
Conference Contribution - Published proceedings: Abstract
Rodger, E. J., Revell, A. F., Jones, G. T., Kleffmann, T., Kettle, A. J., & McCormick, S. P. A. (2007). Proteomic analysis of livers from mice with an atherogenic lipoprotein profile. Journal of Clinical Lipidology, 1(5), (pp. 417). doi: 10.1016/j.jacl.2007.08.016
Parker, S., Forward, K., Jones, G., Williams, M., Cole, J., van Rij, A., & McCormick, S. (2007). Screening for a new 'null' apo(a) allele. New Zealand Medical Journal, 120(1255). Retrieved from http://journal.nzma.org.nz/journal/120-1255/2574/content.pdf
Conference Contribution - Poster Presentation (not in published proceedings)
Tyndall, J. D. A., McCormick, S., & Monk, B. C. (2007, February). The ABC of mapping sequence to structure via homology modelling: A tale of two transporters. Poster session presented at the Proteins: Structure, Function and Assembly in Health and Disease, Rotorua, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Jones, G., van Rij, A., McCormick, S., Deng, M., & Williams, M. (2007, August). Lipoprotein(a) is an independent predictor of atherothromobotic vascular disease. Verbal presentation at the Vascular Conference, Melbourne, Australia.
2006
Journal - Research Article
Slatter, T. L., Williams, M. J. A., Frikke-Schmidt, R., Tybjærg-Hansen, A., Morison, I. M., & McCormick, S. P. A. (2006). Promoter haplotype of a new ABCA1 mutant influences expression of familial hypoalphalipoproteinemia. Atherosclerosis, 187, 393-400.
Conference Contribution - Published proceedings: Abstract
van Rij, A. M., Jones, G. T., Phillips, L. V., Rossaak, J. I., Williams, M. J. A., & McCormick, S. P. A. (2006). Abdominal aortic aneurysm disease is not just atherosclerosis: Genetic and phenotypic comparisons. ANZ Journal of Surgery, 76(Suppl. 1), (pp. A95). doi: 10.1111/j.1445-2197.2006.03822.x
Conference Contribution - Poster Presentation (not in published proceedings)
Rodger, E. J., Revell, A. F., Jones, G. T., Kleffmann, T., & McCormick, S. P. A. (2006, February). Proteomic analysis of structural arterial proteins in a mouse model of atherosclerosis. Poster session presented at the 31st Lorne Proteins Conference, Lorne, Australia.
2005
Journal - Research Article
Jones, G. T., Jiang, F., McCormick, S. P. A., & Dusting, G. J. (2005). Elastic lamina defects are an early feature of aortic lesions in the apolipoprotein E knockout mouse. Journal of Vascular Research, 42, 237-246.
Conference Contribution - Published proceedings: Abstract
Baek, J.-h., Jones, G., Deng, M., van Rij, A., Hammond-Tooke, G., Cole, J., Cleveland, S., & McCormick, S. (2005). Lipoprotein (a): A risk factor for stroke? New Zealand Medical Journal, 118(1215). Retrieved from http://journal.nzma.org.nz/journal/118-1215/1486/content.pdf
Baek, J.-h., Jones, G., Deng, M., van Rij, A., Hammond-Tooke, G., Cole, J., Cleveland, S., & McCormick, S. (2005). Lipoprotein (a): A risk factor for stroke? In S. Bunn, P. Cragg, B. Galland, M. Hibma, T. Merriman, D. Oorschot, … M. Williams (Eds.), Proceedings of the 177th Scientific Meeting of the Otago Medical School Research Society. Dunedin, New Zealand: OMSRS. [Abstract]
2004
Journal - Research Article
Sharp, R. J., Perugini, M. A., Marcovina, S. M., & McCormick, S. P. A. (2004). Structural features of apolipoprotein B synthetic peptides that inhibit lipoprotein(a) assembly. Journal of Lipid Research, 45, 2227-2234.
McCormick, S. P. A. (2004). Lipoprotein(a): Biology and clinical importance. Clinical Biochemist Reviews, 25, 69-80.
Liu, C. Y.-Y., Broadhurst, R., Marcovina, S. M., & McCormick, S. P. A. (2004). Mutation of lysine residues in apolipoprotein B-100 causes defective lipoprotein[a] formation. Journal of Lipid Research, 45, 63-70.
Conference Contribution - Published proceedings: Abstract
Jones, G. T., McCormick, S. P. A., & van Rij, A. M. (2004). Apolipoprotein accumulation in early atherosclerotic lesions. Cardiovascular Pathology. 13, (pp. S121-S122). [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Wang, Y.-T., Sharp, R. J., & McCormick, S. P. A. (2004, December). Effect of an apolipoprotein B peptide on lipoprotein(a) level in transgenic mice. Poster session presented at the 14th Annual Queenstown Molecular Biology Meeting in conjunction with the New Zealand Society for Biochemical and Molecular Biology Conference, Queenstown, New Zealand.
Slatter, T. L., Williams, M. J., Frikke-Schmidt, R., Tybjærg-Hansen, A., Morison, I., & McCormick, S. P. A. (2004, December). ABCA1 promoter haplotypes influence HDL levels in a novel case of Tangier disease. Poster session presented at the 14th Annual Queenstown Molecular Biology Meeting in conjunction with the New Zealand Society for Biochemical and Molecular Biology Conference, Queenstown, New Zealand.
Rodger, E. J., Jones, G., & McCormick, S. P. A. (2004, December). Proteomic analysis of arterial protein expression in a mouse model of atherosclerosis. Poster session presented at the 14th Annual Queenstown Molecular Biology Meeting in conjunction with the New Zealand Society for Biochemical and Molecular Biology Conference, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Jones, G. T., Phillips, L. V., Chu, J. W. S., McCormick, S. P. A., & van Rij, A. M. (2004, September). Differential risk factor associations between three distinct forms of cardiovascular disease. Verbal presentation at the Australian and New Zealand Society for Vascular Surgery Conference, Rotorua, New Zealand.
2003
Chapter in Book - Research
McCormick, S. P. A., Liu, C. Y.-Y., Young, S. G., & Nielsen, L. B. (2003). Manipulating large insert clones for transgenesis. In M. H. Hofker & J. van Deursen (Eds.), Methods in molecular biology: Transgenic mouse methods and protocols. (pp. 105-123). Totowa, NJ: Humana Press.
Journal - Research Article
Sharp, R., Perugini, M. A., Marcovina, S. M., & McCormick, S. P. A. (2003). A synthetic peptide that inhibits lipoprotein(a) assembly. Arteriosclerosis, Thrombosis, & Vascular Biology, 23, 502-507.
Conference Contribution - Published proceedings: Abstract
Forward, K., Cole, J., Jones, G., van Rij, A., & McCormick, S. (2003). Hypobetalipoproteinemia and low levels of lipoprotein(a) in an Otago vascular disease cohort. In P. A. Cragg, B. C. Galland, M. Hibma, Merriman, D. E. Oorschot & M. Williams (Eds.), Proceedings of the 170th Scientific Meeting of the Otago Medical School Research Society. (A5). Dunedin, New Zealand: OMSRS. [Abstract]
2002
Conference Contribution - Published proceedings: Abstract
Revell, A. F., Legge, M., & McCormick, S. P. A. (2002). The effect of a resveratrol-rich wine on LDL oxidation. Atherosclerosis. (Supplement 3). [Abstract]
Callaghan, D. T., & McCormick, S. P. A. (2002). Evidence that a protein disulphide isomerase may play a role in lipoprotein(a) assembly. Atherosclerosis. (Supplement 3). [Abstract]
Sharp, R., Pollock, R., & McCormick, S. P. A. (2002). Structural features of an apolipoprotein B peptide that inhibits lipoprotein(a) assembly. Atherosclerosis. (Supplement 3). [Abstract]
2001
Conference Contribution - Published proceedings: Full paper
McCormick, S. P. A., Sharp, R., Pollock, R., & Hayman, A. R. (2001). A series of apolipoprotein B peptides that inhibit lipoprotein (A) assembly. Proceedings of the 4th Australian Peptide Conference. Lindeman Island, Australia. [Full Paper]
Conference Contribution - Published proceedings: Abstract
Caygill, E. E., Liu, C. Y.-Y., Sharp, R. J., Byers, M., & McCormick, S. (2001). Understanding the protein interactions involved in lipoprotein(a) formation. In P. A. Cragg, N. M. Davies, B. C. Galland, M. Hibma, T. Merriman, M. Williams & S. M. Williams (Eds.), Proceedings of the 157th Scientific Meeting of the Otago Medical School Research Society. (A7). Dunedin, New Zealand: OMSRS. [Abstract]
Caygill, E., Liu, C. Y.-Y., Sharp, R. J., Byers, M., & McCormick, S. P. A. (2001). Understanding the protein interactions involved in lipoprotein (a) formation. Proceedings of the University of Otago Medical School. 79(2). [Abstract]
2000
Journal - Research Article
Cheesman, E. J., Sharp, R., Zlot, C. H., Liu, C. Y.-Y., Taylor, S., Marcovina, S. M., … McCormick, S. P. A. (2000). An analysis of the interaction between mouse apolipoprotein B100 and apolipoprotein (a). Journal of Biological Chemistry, 275(36), 28195-28200. doi: 10.1074/jbc.M002772200
Conference Contribution - Published proceedings: Abstract
McCormick, S. P. A. (2000). Assembly of Lp(a). Atherosclerosis. 151. [Abstract]
Liu, C. Y.-Y., Broadhurst, R., L'Huillier, P. J., & McCormick, S. P. A. (2000). Generation of apolipoprotein B transgenic mice with mutations in a putative apolipoprotein (a) binding region. Atherosclerosis. 151. [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Liu, C. Y.-Y., Pollock, R., & McCormick, S. P. A. (2000, December). The structural features features of apolipoprotein B required for lipoprotein(A) assembly. Poster session presented at the Combined Meeting of the ASBMB, ASPS, NZSBMB, & NZSPP, Wellington, New Zealand.
Sud, A. R., & McCormick, S. P. A. (2000, December). Effects of apolipoprotein B gene variation on human lipoprotein (a) concentrations. Poster session presented at the Combined Meeting of the ASBMB, ASPS, NZSBMB, & NZSPP, Wellington, New Zealand.
Slatter, T. L., Logan, J., & McCormick, S. P. A. (2000, December). Analysing the origin of a cholesterol-lowering mutation in two New Zealand kindred's. Poster session presented at the Combined Meeting of the ASBMB, ASPS, NZSBMB, & NZSPP, Wellington, New Zealand.
Revell, A. F., & McCormick, S. P. A. (2000, December). Trans-resveratrol levels in New Zealand red wines exceed international reported values. Poster session presented at the Combined Meeting of the ASBMB, ASPS, NZSBMB, & NZSPP, Wellington, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Sharp, R. J., Byers, M., & McCormick, S. P. A. (2000, December). A synthetic peptide spanning apolipoprotein B amino acids 4372-4392 inhibits lipoprotein(a) formation. Verbal presentation at the Combined Meeting of the ASBMB, ASPS, NZSBMB, & NZSPP, Wellington, New Zealand.
1999
Journal - Research Article
Zlot, C. H., Flynn, L. M., Veniant, M., Kim, E., Raabe, M., McCormick, S. P. A., … Young, S. G. (1999). Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice. Journal of Lipid Research, 40, 76-84.
Veniant, M., Kim, E., McCormick, S. P. A., Boren, J., Nielsen, L. B., Raabe, M., & Young, S. G. (1999). Insights into apolipoprotein B biology from transgenic and gene-targeted mice. Journal of Nutrition, 129, 451S-455S.
Stafforini, D. M., Tjoelker, L. W., McCormick, S. P. A., Vaitkus, D., McIntyre, T. M., Gray, P. W., … Prescott, S. M. (1999). Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein. Journal of Biological Chemistry, 274(11), 7018-7024. doi: 10.1074/jbc.274.11.7018
Nielsen, L. B., McCormick, S. P. A., & Young, S. G. (1999). A new approach for studying gene regulation by distant DNA elements in transgenic mice. Scandinavian Journal of Clinical & Laboratory Investigation, 59, 33-39.
Conference Contribution - Published proceedings: Abstract
Sharp, R., Pollock, R. C., Bowron, M. E., & McCormick, S. P. A. (1999). A synthetic peptide spanning apolipoprotein B amino acids 4372-4392 inhibits lipoprotein (a) formation. Circulation (American Heart Association 72nd Session). 100, (pp. I-109). [Abstract]
Broom, J. E., Fleming, J. S., Gardiner, S., McCormick, S. P., & Pettus, C. (1999). Genetically modified organisms - marvels or monsters? In C. McDonald & AWIS LOC (Eds.), Proceedings of Living Science. (pp. 76-86). Dunedin: Association for Women in the Sciences. [Abstract]
McCormick, S. P. A., Cheesman, E. J., Zlot, C. H., Liu, C. Y.-Y., & Young, S. G. (1999). The carboxyl terminus of mouse apolipoprotein in B100 supports lipoprotein (a) formation if supplied with cystein-4326. Circulation (American Heart Association 72nd Scientific Session. 100, (pp. I-402). [Abstract]
1998
Journal - Research Article
Dichek, H. L., Brecht, W., Fan, J., Ji, Z.-S., McCormick, S. P. A., Akeefe, H., … Mahley, R. W. (1998). Overexpression of hepatic lipase in transgenic mice decreases apolipoprotein B-containing and high density lipoproteins. Journal of Biological Chemistry, 273(4), 1896-1903. doi: 10.1074/jbc.273.4.1896
McCormick, S. P. A., & Nielsen, L. B. (1998). Expression of large genomic clones in transgenic mice: New insights into apolipoprotein B structure, function and regulation. Current Opinion in Lipidology, 9, 103-111.
Conference Contribution - Published proceedings: Abstract
Bowron, M. E., Liu, C. Y.-Y. Y.-Y., McIntyre, A. J., Sharp, R., & McCormick, S. P. A. (1998). A synthetic apolipoprotein B peptide that inhibits the first step of lipoprotein(a) assembly. Proceedings of the University of Otago Medical School. 76(2). Dunedin. [Abstract]
Cheesman, E. J., & McCormick, S. P. A. (1998). Transgenic mouse models to study the first step of lipoprotein(a) assembly. Proceedings of the University of Otago Medical School. 76(2), (pp. 14). Dunedin. [Abstract]
Liu, C. Y.-Y. Y.-Y., McIntyre, A. J., & McCormick, S. P. A. (1998). Cross species comparison of lipoprotein(a) assembly. Proceedings of the University of Otago Medical School. 76(2), (pp. 23). Dunedin. [Abstract]
1997
Chapter in Book - Research
McCormick, S. P. A., Allan, C. M., Taylor, J. M., & Young, S. G. (1997). The use of P1 bacteriophage clones to generate transgenic animals. In L. M. Houdebine (Ed.), Transgenic Animals: Generation and Use. (pp. 273-281). Amsterdam: Harwood Academic Publishers.
Journal - Research Article
Nielson, L. B., McCormick, S. P. A., Pierotti, V., Tam, C., Gunn, M. D., Shizuya, H., & Young, S. G. (1997). Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artifical chromosomes: Evidence that a distant 5'-element confers appropriate transgene expression in the intestine. Journal of Biological Chemistry, 272(47), 29752-29758. doi: 10.1074/jbc.272.47.29752
McCormick, S. P. A., Ng, J. K., Cham, C. M., Taylor, S., Marcovina, S. M., Segrest, J. P., … Young, S. G. (1997). Transgenic mice expressing human ApoB95 and ApoB97: Evidence that sequences within the carboxyl-terminal portion of human apoB100 are important for the assembly of lipoprotein(a). Journal of Biological Chemistry, 272(38), 23616-23622. doi: 10.1074/jbc.272.38.23616
Conference Contribution - Verbal presentation and other Conference outputs
McCormick, S. P. A., Ng, J. K., Cham, C. C., Taylor, S., Marcovina, S. M., Hammer, R. E., & Young, S. (1997). Transgenic mice expression human apoB95 and apoB97: Evidence that sequences within the carboxyl-terminal portion of human apoB100 are important for Lp(a) assembly. Verbal presentation at the Kern Aspen Lipid Conference, Aspen Colorado.
Nielsen, L. B., Kahn, D., McCormick, S. P. A., Tamm, C., Pierotti, V., Gunn, M. D., … Young, S. G. (1997). Expression of bacterial artificial chromosomes in transgenic mice reveal that intestinal expression of the apoB gene is controlled by DNA sequences between 48 kb and 62 kb 5' of the apoB gene. Verbal presentation at the Kern Aspen Lipid Conference, Aspen Colorado.
1996
Journal - Research Article
McCormick, S. P. A., Ng, J. K., Veniant, M., Boren, J., Pierotti, V., Flynn, L. M., … Young, S. G. (1996). Transgenic mice that overexpress mouse apolipoprotein B: Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural gene. Journal of Biological Chemistry, 271(20), 11963-11970. doi: 10.1074/jbc.271.20.11963
McCormick, S. P. A., Peterson, K. R., Hammer, R. E., Clegg, C. H., & Young, S. G. (1996). Generation of transgenic mice from yeast artificial chromosome DNA that has been modified by gene targeting. Trends in Cardiovascular Medicine, 6(1), 16-24. doi: 10.1016/1050-1738(95)00125-5
Young, S. G., Krul, E. S., McCormick, S., Farese, Jr, R. V., & Linton, M. F. (1996). Identification and characterization of truncated forms of apolipoprotein B in hypobetalipoproteinemia. Methods in Enzymology, 263, 120-145.
1995
Journal - Research Article
McCormick, S. P. A., Day, W. A., & George, P. M. (1995). Characterization of lipoproteins containing a truncated form of apolipoprotien B, apolipoprotien B32. Biochimica et Biophysica Acta: General Subjects, 1258(1), 49-56. doi: 10.1016/0005-2760(95)00096-U