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Pharmaceutical sciences

We aim to extend the range of drugs available, and to provide a scientific basis for the quality use of medicines and bioactive substances.

 School of Pharmacy pharmaceutical sciences research includes:

  • Drug discovery
  • Drug metabolism
  • Drug action

Research in metabolism has been designated an 'Area of Research Strength' by the University.

From drug to medicine

Specific areas of expertise are:

  • Computational methods encompassing rational, structure and analogue based drug design techniques
  • QSAR (Quantitative Structural Activity Relationship software)
  • Drug target identification and lead optimisation
  • Chemical synthesis of bioactive compounds
  • Preclinical assessment of new chemical entities including small molecular weight and polypeptide bioactives
  • Development of analytical methods for drugs in formulations and body fluids
  • Studies on drugs of abuse aimed at harm minimization, and for application in forensic toxicology
  • Pharmacokinetic and toxicity studies on synthetic bioactives and those extracted from natural sources

Pharmaceutical equipment

For initial advice contact:

Equipment

  •  Liquid Chromatography - Mass Spectrometry (LC-MS)
    • ABSciex 3200 triple quad
    • Agilent 6430 triple quad
    • ABSciex QTrap (triple quad plus ion trap)
  • Agilent preparative and semi-preparative HPLC (High Performance Liquid Chromatography)
  • Particle sizer
  • Rheometer
  • Texture analyser
  • Analytical HPLC (UV, ELSD and MS detectors),
  • Infrared (IR) and fluorescence spectroscopy
  • Photochemical reactor
  • Molecular modelling computers with ligand docking programs (e.g. GOLD)