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Dr Golnoush Madani

Contact Details

Phone
+64 3 479 5190
Email
golnoush.madani@otago.ac.nz
Position
Postdoctoral fellow
Department
Department of Biochemistry
Qualifications
MSc, PhD
Research summary
Lipoproteins and cardiovascular disease

Research

Golnoush received her MSc in Biotechnology (2008), at the Isfahan University of Technology, Iran. She was lecturer and lab manager at the Isfahan University of Medical Sciences, before joining the Molecular Microbiology programme of the Sir John Walsh Research Institute at the University of Otago in October 2015 to undertake PhD studies into the structure and function of a Candida pleiotropic drug resistance transporter, Cdr1. As part of her project, Golnoush spent six months working at the Max Planck Institute for Molecular Physiology in Germany, with support from a grant from the German Academic Exchange Service, DAAD, awarded in 2018. After receiving her PhD, she moved to the Department of Biochemistry to join Professor Sally McCormicks lab as the PostDoc Fellow.

Currently she is utilising biochemical and imaging approaches to investigate lipoprotein metabolism, a key risk factor in the development of cardiovascular disease (CVD).

Publications

Siddiqui, H., Yevstigneyev, N., Madani, G., & McCormick, S. (2022). Approaches to visualising endocytosis of LDL-related lipoproteins. Biomolecules, 12, 158. doi: 10.3390/biom12020158 Journal - Research Other

Madani, G., Lamping, E., Lee, H. J., Niimi, M., Mitra, A. K., & Cannon, R. D. (2021). Small-scale plasma membrane preparation for the analysis of Candida albicans Cdr1-mGFPHis. Journal of Visualized Experiments, 172, e62592. doi: 10.3791/62592 Journal - Research Article

Madani, G., Lamping, E., & Cannon, R. D. (2021). Engineering a cysteine-deficient functional Candida albicans Cdr1 molecule reveals a conserved region at the cytosolic apex of ABCG transporters important for correct folding and trafficking of Cdr1. mSphere, 6(1), e01318-20. doi: 10.1128/mSphere.01318-20 Journal - Research Article

Madani, G. (2020). Biochemical and structural analysis of Candida albicans multidrug efflux pump Cdr1 (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/10249 Awarded Doctoral Degree

Madani, G., Lamping, E., Bostina, M., Raunser, S., Hall, N., Mitra, A., & Cannon, R. D. (2019, September). Expression, purification, and negative staining of Candida albicans plasma membrane protein Cdr1. Verbal presentation at the Sir John Walsh Research Institute Research Day, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs

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