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Chris PembertonResearch Professor

Email chris.pemberton@otago.ac.nz

Christchurch Heart Institute
Department of Medicine
University of Otago, Christchurch
PO Box 4345
Christchurch 8140
New Zealand

Current roles

  • Director, Translational Biodiscovery Laboratory, Christchurch Heart Institute
  • Named Investigator on the current Christchurch Heart Institute HRC Programme grant.
  • Principal Investigator on HRC, MBIE and WADA funded signal peptide projects
  • Research Professor, Department of Medicine

Research interests

  • Novel protein/peptide biomarker identification and measurement
  • Cardioendocrine signalling in the circulation and heart tissue
  • Ex vivo study of novel cardiovascular diagnostic and therapeutic agents
  • Commercialisation of biomedical technologies

Awards and professional memberships

  • 2012- Research Commercialisation – Strategic and Implementation Committee, Division of Health Sciences.
  • 2012- Corresponding Member, Canterbury, NZ Society of Endocrinology
  • 2011 Health Research Council of New Zealand Liley Medal
  • 2011- European Society for Cardiology, Working Group on Cellular Biology of the Heart
  • 2010- American Association of Clinical Chemistry
  • 2007-11 Health Research Council of New Zealand Sir Charles Hercus Fellowship
  • 2006-2009 Treasurer, Executive Committee Member, NZ Society of Endocrinology

Publications

Appleby, S., Aitken-Buck, H. M., Holdaway, M. S., Byers, M. S., Frampton, C. M., Paton, L. N., Richards, A. M., Lamberts, R. R., & Pemberton, C. J. (2024). Cardiac effects of myoregulin in ischemia-reperfusion. Peptides, 174, 171156. doi: 10.1016/j.peptides.2024.171156

Appleby, S., Frampton, C., Holdaway, M., Chew-Harris, J., Liew, O. W., Chong, J. P. C., Lewis, L., Troughton, R., … Richards, A. M., & Pemberton, C. J. (2023). Circulating erythroferrone has diagnostic utility for acute decompensated heart failure in patients presenting with acute or worsening dyspnea. Frontiers in Cardiovascular Medicine, 10, 1195082. doi: 10.3389/fcvm.2023.1195082

Montecillo, J., Pirker, T., Richards, M., Pemberton, C., & Chew-Harris, J. (2023). Protein glycosylation influences soluble urokinase Plasminogen Activator Receptor (suPAR) measurements. Heart, Lung & Circulation, 32(Suppl. 2), P16. doi: 10.1016/j.hlc.2023.04.237

Pirker, T., Keys, T., Pham, T., Montecillo, J., Byers, M., Pemberton, C., Richards, M., & Chew-Harris, J. (2023). Soluble urokinase Plasminogen Activator Receptor (suPAR) promotes cardioprotective intracellular signalling in myocardial ischaemia. Heart, Lung & Circulation, 32(Suppl. 2), O02. doi: 10.1016/j.hlc.2023.04.208

Doudesis, D., Lee, K. K., Boeddinghaus, J., Bularga, A., Ferry, A. V., Tuck, C., … Pickering, J. W., Than, M. P., … CoDE-ACS Investigators, including Richards, A. M., Pemberton, C., Troughton, R. W., & Aldous, S. J. (2023). Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations. Nature Medicine, 29, 1201-1210. doi: 10.1038/s41591-023-02325-4

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