Dr Michael J. Epton, Our people, University of Otago, Christchurch

BM BS BMedSci(Hons) MRCP(UK) FRACP PhD

Email michael.epton@cdhb.health.nz

Canterbury Respiratory Research Group
40 Stewart St
Christchurch
New Zealand

Current Roles

2016 - Present
Adjunct Professor, Departments of Geography, and Communication Disorders, University of Canterbury, Christchurch, New Zealand
November 2014 - Present
Investigator (Christchurch Clinical Studies Trust, New Zealand)
February 2010 - Present
Community Respiratory Physician, Canterbury Initiative, Christchurch, New Zealand
January 2009 - Present
Consultant Physician, Department of Respiratory Medicine, Christchurch Hospital, New Zealand
July 2002 - Present
Director, The Canterbury Respiratory Research Group, Christchurch, New Zealand

Research Interests

Asthma, allergy and airway inflammation
Air Pollution and airway inflammation
COPD
Alpha-1 anti-trypsin deficiency
Beta agonist pharmacogenetics
Exhaled Breath Condensate

Top 10 Publications

Darlow BA, Horwood LJ, Woodward LJ, Elliott JM, Troughton RW, Elder MJ, Epton MJ, Stanton JD, Swanney MP, Keenan R, Melzer TR, McKelvey VA, Levin K, Meeks MG, Espiner EA, Cameron VA, Martin J. The New Zealand 1986 very low birth weight cohort as young adults: mapping the road ahead. BMC Pediatr. 2015 Aug 5;15:90
Storer M, Curry K, Squire M, Kingham S, Epton M. Breath testing and personal exposure--SIFT-MS detection of breath acetonitrile for exposure monitoring. J Breath Res. 2015 May 26;9(3):036006
Frith PA, Thompson PJ, Ratnavadivel R, Chang CL, Bremner P, Day P, Frenzel C, Kurstjens N; Glisten Study Group. Glycopyrronium once-daily significantly improves lung function and health status when combined with salmeterol/fluticasone in patients with COPD: the GLISTEN study, a randomised controlled trial. Thorax. 2015 Jun;70(6):519-27.
Epton MJ, Stanton JD, McGeoch GR, Shand BI, Swanney MP. The development of a community-based spirometry service in the Canterbury region of New Zealand: observations on new service delivery. NPJ Prim Care Respir Med. 2015 Mar 5;25:15003.
Magnussen H, Disse B, Rodriguez-Roisin R, Kirsten A, Watz H, Tetzlaff K, Towse L, Finnigan H, Dahl R, Decramer M, Chanez P, Wouters EF, Calverley PM; WISDOM Investigators. Withdrawal of inhaled glucocorticoids and exacerbations of COPD. N Engl J Med. 2014 Oct 2;371(14):1285-94
Storer M., Salmond J., Dirks K.N., Kingham, S., Epton, M. Mobile selected ion flow tube mass spectrometry (SIFT-MS) devices and their use for pollution exposure monitoring in breath and ambient air-pilot study. Journal of Breath Research 2014;8(3).
Maze M.J., Slow S., Cumins A.M., Boon K., Goulter P., Podmore R.G., Anderson T.P., Barratt K., Young S.A., Pithie A.D., Epton M.J., Werno A.M., Chambers S.T., Murdoch D.R. Enhanced detection of Legionnaires' disease by PCR testing of induced sputum and throat swabs. European Respiratory Journal 2014;43(2):644-646.
Scott-Thomas A., Epton M., Chambers S. Validating a breath collection and analysis system for the new tuberculosis breath test. Journal of Breath Research 2013;7(3)
Sturney S.C., Storer M.K., Shaw G.M., Shaw D.E., Epton M.J. Off-line breath acetone analysis in critical illness. Journal of Breath Research 2013;7(3)
Scott-Thomas A., Syhre M., Epton, M., Murdoch D.R., Chambers S.T. Assessment of potential causes of falsely positive Mycobacterium tuberculosis breath test. Tuberculosis 2013;93(3):312-317
Dummer J., Storer M., Sturney S., Scott-Thomas A., Chambers S., Swanney M., Epton E. Quantification of hydrogen cyanide (HCN) in breath using selected ion flow tube mass spectrometry - HCN is not a biomarker of Pseudomonas in chronic suppurative lung disease. Journal of Breath Research 2013;7(1). doi:10.1088/1752-7155/7/1/017105

Publications

Maze, M. J., Williman, J., Anstey, R., Best, E., Bhally, H., Bryce, A., … Dummer, J., Epton, M., … Hancox, R. J., … Murdoch, D. R., … Raymond, N., … Walls, T., … Wright, K. (2024). Evaluation of risk prediction scores for adults hospitalised with COVID-19 in a highly vaccinated population, Aotearoa New Zealand 2022. IJID Regions. Advance online publication. doi: 10.1016/j.ijregi.2024.100424 Journal - Research Article

Hobbs, M., Marek, L., McLeod, G. F. H., Woodward, L. J., Sturman, A., Kingham, S., Ahuriri-Driscoll, A., Epton, M., Eggleton, P., … Boden, J. (2024). Exploring the feasibility of linking historical air pollution data to the Christchurch Health and Development study: A birth cohort study in Aotearoa, New Zealand. Spatial & Spatio-temporal Epidemiology, 50, 100675. doi: 10.1016/j.sste.2024.100675 Journal - Research Article

Maze, M., Williman, J., Best, E., Bhally, H., Bryce, A., Chang, C., … Dummer, J., Epton, M., Good, W., … Hancox, R., … Hills, T., … Morpeth, S., Murdoch, D., … Raymond, N., … Storer, M., Walls, T., … Wong, C., & Wright, K. (2024). Evaluation of COVID-19 severity prediction scores, Aotearoa New Zealand 2022. Respirology, 29(Suppl. 1), TO118. doi: 10.1111/resp.14673 Conference Contribution - Published proceedings: Abstract

Harris, S. L., Jones, G. T., Pilbrow, A. P., Horwood, L. J., Martin, J., Frampton, C., Ip, W. T., Troughton, R. W., Greer, C., Yang, J., Epton, M. J., … Darlow, B. A., & Cameron, V. A. (2024). DNA methylation patterns at birth predict later-life health related pathobiology. Journal of Paediatrics & Child Health, 60(Suppl. 1), (pp. 107-108). doi: 10.1111/jpc.16526 Conference Contribution - Published proceedings: Abstract

Zhang, X., Wilkinson, A., Storer, M., & Epton, M. J. (2023). Impact of COVID-19 and lockdown on COPD admissions to Christchurch Hospital, New Zealand 2020-2021: A combined quantitative and qualitative study. Internal Medicine Journal, 53, 1768-1775. doi: 10.1111/imj.16204 Journal - Research Article

2024

Journal - Research Article

Conference Contribution - Published proceedings: Abstract

2023

Journal - Research Article

Chambers, S. T., Scott-Thomas, A., Storer, M., Slow, S., Williman, J., Epton, M., Murdoch, D. R., Metcalf, S., Carr, A., Isenman, H., & Maze, M. (2023). Adjunctive intravenous then oral vitamin C for moderate and severe community-acquired pneumonia in hospitalized adults: Feasibility of randomized controlled trial. Scientific Reports, 13, 11879. doi: 10.1038/s41598-023-37934-z

Cameron, V. A., Jones, G. T., Horwood, L. J., Pilbrow, A. P., Martin, J., Frampton, C., Ip, W. T., Troughton, R. W., Greer, C., Yang, J., Epton, M. J., Harris, S. L., & Darlow, B. A. (2023). DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight. Clinical Epigenetics, 15, 47. doi: 10.1186/s13148-023-01463-3

Cheung, J., Nordmeier, K., Kelland, S., Harrington, M., Williman, J., Storer, M., Beaglehole, B., Beckert, L., Chambers, S. T., Epton, M. J., Freeman, J., Murdoch, D. R., Werno, A. M., & Maze, M. J. (2023). Symptom persistence and recovery among COVID-19 survivors during a limited outbreak in Canterbury, New Zealand: A prospective cohort study. Internal Medicine Journal, 53, 37-45. doi: 10.1111/imj.15930

2022

Journal - Research Article

Bryce, A., Foley, L., Phillipson, J., Slow, S., Storer, M., Williman, J., Beasley, R., Bhally, H., … Dummer, J., Epton, M., … Gracie, K., Hancox, R. J., Hills, T., Hogg, S., … Kearns, N., … Murdoch, D., Raymond, N., … Maze, M. J. (2022). Clinical features of patients hospitalised with COVID-19 from February to October 2020, during the early waves of the pandemic in New Zealand. New Zealand Medical Journal, 135(1552), 120-130. Retrieved from https://journal.nzma.org.nz/

Yang, J., Epton, M. J., Harris, S. L., Horwood, J., Kingsford, R. A., Troughton, R., Greer, C., & Darlow, B. A. (2022). Reduced exercise capacity in adults born at very low birth weight: A population-based cohort study. American Journal of Respiratory & Critical Care Medicine, 205, 88-98. doi: 10.1164/rccm.202103-0755OC

2021

Journal - Research Article

Vannier, C., Mulligan, H., Wilkinson, A., Elder, S., Malik, A., Morrish, D., … Epton, M. (2021). Strengthening community connection and personal well-being through volunteering in New Zealand. Health & Social Care in the Community, 29, 1971-1979. doi: 10.1111/hsc.13340

McNeill, R. P., Zhang, M., Epton, M. J., & Doogue, M. P. (2021). Drub metabolism in severe chronic obstructive pulmonary disease: A phenotyping cocktail study. British Journal of Clinical Pharmacology, 87, 4397-4407. doi: 10.1111/bcp.14862

2020

Journal - Research Article

Yang, J., Kingsford, R. A., Horwood, J., Epton, M. J., Swanney, M. P., Stanton, J., & Darlow, B. A. (2020). Lung function of adults born at very low birth weight. Pediatrics, 145(2), e20192359. doi: 10.1542/peds.2019-2359

2019

Journal - Research Article

Hoskin, T. S., Crowther, J. M., Cheung, J., Epton, M. J., Sly, P. D., Elder, P. A., … Kettle, A. J., & Dickerhof, N. (2019). Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis. Redox Biology, 24, 101202. doi: 10.1016/j.redox.2019.101202

2018

Journal - Research Article

Slow, S., Epton, M., Storer, M., Thiessen, R., Lim, S., Wong, J., Chin, P., Tovaranonte, P., Pearson, J., Chambers, S. T., Murdoch, D. R., and VIDCAPS Group, including Jardine, D., & Pithie, A. (2018). Effect of adjunctive single high-dose vitamin D₃ on outcome of community-acquired pneumonia in hospitalised adults: The VIDCAPS randomised controlled trial. Scientific Reports, 8(1), 13829. doi: 10.1038/s41598-018-32162-2

Pattemore, P. K., Silvers, K. M., Frampton, C. M., Wickens, K., Ingham, T., Fishwick, D., Crane, J., Town, G. I., Epton, M. J., on behalf of the New Zealand Asthma and Allergy Cohort Study Group, including Lampshire, P., Leadbitter, P., Nicholson, A., & Siebers, R. (2018). Hair nicotine at 15 months old, tobacco exposure and wheeze or asthma from 15 months to 6 years old. Pediatric Pulmonology, 53(4), 443-451. doi: 10.1002/ppul.23903

Conference Contribution - Published proceedings: Full paper

Yang, J., Epton, M., Darlow, B., Horwood, J., Martin, J., & Swanney, M. P. (2018). Effects of very low birth weight and bronchopulmonary dysplasia on adult pulmonary function. American Journal of Respiratory & Critical Care Medicine, 197, A2325. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Yang, J., Kingsford, R., Epton, M., Swanney, M. P., Horwood, L. J., Martin, J., & Darlow, B. A. (2018). Effects of very low birth weight (VLBW) and bronchopulmonary dysplasia (BPD) on adult pulmonary function. Journal of Paediatrics & Child Health, 54(Suppl. 1), (pp. 53). doi: 10.1111/jpc.13881

Wilkinson, A., Mulligan, H., Purvis, C., Campbell, M., Kingham, S., Kerdemeledis, M., … Storer, M., & Epton, M. (2018). WellConnectedNZ: Te Ranga i te Tira: Improving individuals' health by strengthening community connectedness. Proceedings of the Third International Conference on Wellbeing & Public Policy. (pp. 88). Retrieved from https://www.confer.nz/wellbeingandpublicpolicy2018

2016

Journal - Research Article

McEvoy, R. D., Antic, N. A., Heeley, E., Luo, Y., Ou, Q., Zhang, X., … for the SAVE Investigators and Coordinators, including Epton, M. J., Brockway, B., Cowan, J., Taylor, D. R., Palmay, R., Ferrier, K., & Neill, A. (2016). CPAP for prevention of cardiovascular events in obstructive sleep apnea. New England Journal of Medicine, 375(10), 919-932. doi: 10.1056/NEJMoa1606599

Conference Contribution - Verbal presentation and other Conference outputs

Epton, M. (2016, August). Secondary care perspective. Verbal presentation at the South General Practice Conference & Medical Exhibition (GP CME), Christchurch, New Zealand.

2015

Journal - Research Other

Darlow, B. A., Horwood, L. J., Woodward, L. J., Elliott, J. M., Troughton, R. W., Elder, M. J., Epton, M. J., Stanton, J. D., Swanney, M. P., Keenan, R., Melzer, T. R., McKelvey, V. A., Levin, K., Meeks, M. G., Espiner, E. A., Cameron, V. A., & Martin, J. (2015). The New Zealand 1986 very low birth weight cohort as young adults: Mapping the road ahead. BMC Pediatrics, 15, 90. doi: 10.1186/s12887-015-0413-9

Conference Contribution - Published proceedings: Abstract

Chen, D., Curtis, J., Braithwaite, L., van der Pol, S., Epton, M., & Mulligan, H. (2015). Is the one-minute sit-to-stand test an appropriate replacement for the six-minute walk test in community pulmonary rehabilitation programmes? Physiotherapy, 101(Suppl. 1), (pp. e222). doi: 10.1016/j.physio.2015.03.392

Dummer, J., Storer, M., Swanney, M. P., Frampton, C., & Epton, M. (2015). Analysis of hydrogen sulfide in breath. American Journal of Respiratory & Critical Care Medicine, 191(Meetings Abstracts). Retrieved from http://www.atsjournals.org/series/ajrccm-conference

2014

Journal - Research Other

Maze, M. J., Slow, S., Cumins, A.-M., Boon, K., Goulter, P., Podmore, R. G., … Pithie, A. D., Epton, M. J., Werno, A. M., Chambers, S. T., & Murdoch, D. R. (2014). Enhanced detection of Legionnaires' disease by PCR testing of induced sputum and throat swabs. European Respiratory Journal, 43(2), 644-646. doi: 10.1183/09031936.00191913

2013

Journal - Research Article

Storer, M., Dummer, J., Sturney, S., & Epton, M. (2013). Validating SIFT-MS analysis of volatiles in breath. Current Analytical Chemistry, 9(4), 576-583. doi: 10.2174/15734110113099990022

Scott-Thomas, A., Epton, M., & Chambers, S. (2013). Validating a breath collection and analysis system for the new tuberculosis breath test. Journal of Breath Research, 7(3), 037108. doi: 10.1088/1752-7155/7/3/037108

Dummer, J., Storer, M., Sturney, S., Scott-Thomas, A., Chambers, S., Swanney, M., & Epton, M. (2013). Quantification of hydrogen cyanide (HCN) in breath using selected ion flow tube mass spectrometry: HCN is not a biomarker of Pseudomonas in chronic suppurative lung disease. Journal of Breath Research, 7(1), 017105. doi: 10.1088/1752-7155/7/1/017105

Scott-Thomas, A., Syhre, M., Epton, M., Murdoch, D. R., & Chambers, S. T. (2013). Assessment of potential causes of falsely positive Mycobacterium tuberculosis breath test. Tuberculosis, 93(3), 312-317. doi: 10.1016/j.tube.2013.01.005

Conference Contribution - Published proceedings: Full paper

Sturney, S. C., Storer, M. K., Shaw, G. M., Shaw, D. E., & Epton, M. J. (2013). Off-line breath acetone analysis in critical illness. Journal of Breath Research, 7(3), 037102. doi: 10.1088/1752-7155/7/3/037102

Conference Contribution - Published proceedings: Abstract

Sturney, S. C., Storer, M. K., Shaw, G. M., Kennedy, R. R., Shaw, D. E., & Epton, M. J. (2013). An off-line end-tidal breath sampling method in anaesthetised patients with analysis by selected ion flow tube mass spectrometry. Thorax, 68(Suppl. 3), (pp. A158). doi: 10.1136/thoraxjnl-2013-204457.335

2012

Journal - Research Article

Chambers, S. T., Scott-Thomas, A., & Epton, M. (2012). Developments in novel breath tests for bacterial and fungal pulmonary infection. Current Opinion in Pulmonary Medicine, 18(3), 228-232. doi: 10.1097/MCP.0b013e328351f98b

Thomson, C. D., Wickens, K., Miller, J., Ingham, T., Lampshire, P., Epton, M. J., Town, G. I., Pattemore, P., Crane, J., and the Year Six New Zealand Asthma and Allergy Cohort Study Group, (NZAACS6) including Siebers, R. (2012). Selenium status and allergic disease in a cohort of New Zealand Children. Clinical & Experimental Allergy, 42(4), 560-567. doi: 10.1111/j.1365-2222.2011.03924.x

Silvers, K. M., Frampton, C. M., Wickens, K., Pattemore, P. K., Ingham, T., Fishwick, D., Crane, J., Town, G. I., Epton, M. J., on behalf of the New Zealand Asthma and Allergy Cohort Study Group, including Duignan, M., Irvine, V., Lampshire, P., Leadbitter, P., & Siebers, R. (2012). Breastfeeding protects against current asthma up to 6 years of age. Journal of Pediatrics, 160(6), 991-996. doi: 10.1016/j.jpeds.2011.11.055

Tanpowpong, P., Ingham, T. R., Lampshire, P. K., Kirchberg, F. F., Epton, M. J., Crane, J., … and the New Zealand Asthma and Allergy Cohort Study Group, including Pattemore, P., Siebers, R., & Wickens, K. (2012). Coeliac disease and gluten avoidance in New Zealand children. Archives of Disease in Childhood, 97, 12-16. doi: 10.1136/archdischild-2011-300248

Crane, J., Lampshire, P., Wickens, K., Epton, M., Siebers, R., Ingham, T., Pattemore, P., Town, I., and the Year Six New Zealand Asthma and Allergy Cohort Study Group, (NZAACS6) . (2012). Asthma, atopy and exhaled nitric oxide in a cohort of 6-yr-old New Zealand children. Pediatric Allergy & Immunology, 23(1), 59-64. doi: 10.1111/j.1399-3038.2011.01227.x

Conference Contribution - Published proceedings: Abstract

Scott-Thomas, A., Syhre, M., Epton, M., Murdoch, D. R., & Chambers, S. T. (2012). Assessment of potential causes of falsely positive Mycobacterium tuberculosis breath test. Proceedings of the 5th Annual Otago International Health Research Network (OIHRN) Conference. Retrieved from http://dnmeds.otago.ac.nz/departments/psm/research/international_hlth/conference/programme.html

Conference Contribution - Verbal presentation and other Conference outputs

Epton, M. (2012, September). Community programmes to reduce respiratory admissions: What can we learn? Plenary presentation at the New Zealand Respiratory Conference, Wellington, New Zealand.

2011

Journal - Research Article

Storer, M., Dummer, J., Lunt, H., Scotter, J., McCartin, F., Cook, J., Swanney, M., … Epton, M. (2011). Measurement of breath acetone concentrations by selected ion flow tube mass spectrometry in type 2 diabetes. Journal of Breath Research, 5, 046011. doi: 10.1088/1752-7155/5/4/046011

Storer, M. K., Dummer, J. F., Cook, J., McEwan, M., & Epton, M. J. (2011). Increased concentrations of breath haloamines are not detectable in airways inflammation using SIFT-MS. Journal of Breath Research, 5(3). doi: 10.1088/1752-7155/5/3/037105

Bhandari, S., Chambers, S., Pearson, J., Syhre, M., Epton, M., & Scott-Thomas, A. (2011). Determining the limits and confounders for the 2-pentyl furan breath test by gas chromatography/mass spectrometry. Journal of Chromatography B, 879(26), 2815-2820. doi: 10.1016/j.jchromb.2011.08.010

Dummer, J., Storer, M., Swanney, M., McEwan, M., Scott-Thomas, A., Bhandari, S., Chambers, S., … Epton, M. (2011). Analysis of biogenic volatile organic compounds in human health and disease. Trends in Analytical Chemistry, 30(7), 960-967. doi: 10.1016/j.trac.2011.03.011

Fukuda, K., Hider, P. N., Epton, M. J., Jennings, L. C., & Kingham, S. (2011). Including viral infection data supports an association between particulate pollution and respiratory admissions. Australian & New Zealand Journal of Public Health, 35(2), 163-169. doi: 10.1111/j.1753-6405.2010.00620.x

Young, R. P., Hopkins, R. J., Whittington, C. F., Hay, B. A., Epton, M. J., & Gamble, G. D. (2011). Individual and cumulative effects of GWAS susceptibility loci in lung cancer: Associations after sub-phenotyping for COPD. PLoS ONE, 6(2), e16476. doi: 10.1371/journal.pone.0016476

Camargo, Jr, C. A., Ingham, T., Wickens, K., Thadhani, R., Silvers, K. M., Epton, M. J., Town, G. I., Pattemore, P. K., … Crane, J., and the New Zealand Asthma and Allergy Cohort Study Group, including Duignan, M., Irvine, V., Lampshire, P., Leadbitter, P., & Siebers, R. (2011). Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics, 127(1), e180-e187. doi: 10.1542/peds.2010-0442

Wickens, K., Beasley, R., Town, I., Epton, M., Pattemore, P., Ingham, T., Crane, J., and the New Zealand Asthma and Allergy Cohort Study Group, including Duignan, M., Irvine, V., Lampshire, P., Leadbitter, P., & Siebers, R. (2011). The effects of early and late paracetamol exposure on asthma and atopy: A birth cohort. Clinical & Experimental Allergy, 41(3), 399-406. doi: 10.1111/j.1365-2222.2010.03610.x

Conference Contribution - Published proceedings: Abstract

Barthow, C., Wickens, K., Ingham, T., Swanney, M., Stanton, J., Lampshire, P., Town, I., Epton, M., Pattemore, P., Crane, J., and the New Zealand Asthma and Allergy Cohort Study Group. (2011). Spirometry quality control and ability to predict asthma in 6 yr old children. Proceedings of the Annual Scientific Meetings of The Thoracic Society of Australia and New Zealand (TSANZ) & The Australian and New Zealand Society of Respiratory Science (ANZSRS). TP-004. Retrieved from http://www.fcconventions.com.au/TSANZ2011/08.pdf

Siebers, R., Lampshire, P., Wickens, K., Ingham, T., Epton, M., Town, I., & Crane, J. (2011). Specific IgE sensitisation in a six-year old infant cohort in New Zealand. Proceedings of the XXII World Allergy Congress. Retrieved from http://wao.confex.com/wao/2011wac/webprogram/start.html

Siebers, R., Lampshire, P., Wickens, K., Ingham, T., Epton, M., Town, I., & Crane, J. (2011). Specific IgE sensitisation in a six-year old infant cohort in New Zealand. Proceedings of the Annual Congress of the European Respiratory Society (ERS). Retrieved from http://www.ers-education.org/ersMade/abstract_print_11/main_frameset.htm

Barthow, C., Wickens, K., Ingham, T., Swanney, M., Stanton, J., Lampshire, P., Town, I., Epton, M., Pattemore, P., Crane, J., The New Zealand Asthma and Allergy Cohort Study Group. (2011). Spirometry quality control and ability to predict asthma in 6-year-old children. Respirology, 16(Suppl. 1), (pp. 37). doi: 10.1111/j.1440-1843.2011.01937_1.x

2010

Journal - Research Article

Scott-Thomas, A. J., Syhre, M., Pattemore, P. K., Epton, M., Laing, R., Pearson, J., & Chambers, S. T. (2010). 2-Aminoacetophenone as a potential breath biomarker for Pseudomonas aeruginosa in the cystic fibrosis lung. BMC Pulmonary Medicine, 10, 56. doi: 10.1186/1471-2466-10-56

Dummer, J. F., . . ., Frampton, C. M., Scotter, J. M., Prisk, G., & Epton, M. J. (2010). Accurate, reproducible measurement of acetone concentration in breath using selected ion flow tube-mass spectrometry. Journal of Breath Research, 4, 046001. doi: 10.1088/1752-7155/4/4/046001

Young, R. P., Whittington, C. F., Hopkins, R. J., Hay, B. A., Epton, M. J., Black, P. N., & Gamble, G. D. (2010). Chromosome 4q31 locus in COPD is also associated with lung cancer. European Respiratory Journal, 36(6), 1375-1382. doi: 10.1183/09031936.00033310

Hu, W.-P., Langford, V. S., McEwan, M. J., Milligan, D. B., Storer, M. K., Dummer, J., & Epton, M. J. (2010). Monitoring chloramines and bromamines in a humid environment using selected ion flow tube mass spectrometry. Rapid Communications in Mass Spectrometry, 24(12), 1744-1748. doi: 10.1002/rcm.4570

Camargo, Jr, C. A., Ingham, T., Wickens, K., Thadhani, R. I., Silvers, K. M., Epton, M. J., Town, G. I., … Crane, J., and the New Zealand Asthma and Allergy Cohort Study Group, including Leadbitter, P., Pattemore, P., & Siebers, R. (2010). Vitamin D status of newborns in New Zealand. British Journal of Nutrition, 104(7), 1051-1057. doi: 10.1017/S0007114510001674

Conference Contribution - Verbal presentation and other Conference outputs

Thomson, C., Miller, J., Wickens, K., Ingham, T., Epton, M., Town, I., Pattemore, P., Crane, J., and the New Zealand Asthma and Allergy Cohort Study Group. (2010, May-June). Selenium status and atopy in a cohort of New Zealand children. Verbal presentation at the 9th International Symposium on Selenium in Biology and Medicine, Kyoto, Japan.

2009

Journal - Research Article

Dummer, J. F., Epton, M. J., Cowan, J. O., Cook, J. M., Condliffe, R., Landhuis, C. E., Smith, A. D., & Taylor, D. R. (2009). Predicting corticosteroid response in chronic obstructive pulmonary disease using exhaled nitric oxide. American Journal of Respiratory & Critical Care Medicine, 180(9), 846-852. doi: 10.1164/rccm.200905-0685OC

Young, R. P., Hopkins, R. J., Hay, B. A., Epton, M. J., Mills, G. D., Black, P. N., … Gamble, G. D. (2009). A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers. Postgraduate Medical Journal, 85(1008), 515-524. doi: 10.1136/pgmj.2008.077107

Laugesen, M., Epton, M., Frampton, C. M. A., Glover, M., & Lea, R. A. (2009). Hand-rolled cigarette smoking patterns compared with factory-made cigarette smoking in New Zealand men. BMC Public Health, 9, 194. doi: 10.1186/1471-2458-9-194

Silvers, K. M., Frampton, C. M., Wickens, K., Epton, M. J., Pattemore, P. K., Ingham, T., … Crane, J., Town, G. I., and the New Zealand Asthma and Allergy Cohort Study Group, including Duignan, M., Irvine, V., Lampshire, P., Leadbitter, P., & Siebers, R. (2009). Breastfeeding protects against adverse respiratory outcomes at 15 months of age. Maternal & Child Nutrition, 5(3), 243-250. doi: 10.1111/j.1740-8709.2008.00169.x

Epton, M. J., Ledingham, K., Dummer, J., Hu, W.-P., Rhodes, B., Senthilmohan, S. T., Scotter, J. M., Allardyce, R., Cook, J., & Swanney, M. P. (2009). Interference of chlorofluorocarbon (CFC)-containing inhalers with measurements of volatile compounds using selected ion flow tube mass spectrometry. Rapid Communications in Mass Spectrometry, 23(3), 443-447. doi: 10.1002/rcm.3875

Young, R. P., Hopkins, R. J., Hay, B. A., Epton, M. J., Mills, G. D., Black, P. N., … Gamble, G. D. (2009). Lung cancer susceptibility model based on age, family history and genetic variants. PLoS ONE, 4(4), e5302. doi: 10.1371/journal.pone.0005302

Chambers, S. T., Syhre, M., Murdoch, D. R., McCartin, F. J., & Epton, M. J. (2009). Detection of 2-Pentylfuran in the breath of patients with Aspergillus fumigatus. Medical Mycology, 47(5), 468-476. doi: 10.1080/13693780802475212

2008

Journal - Research Article

Tashkin, D. P., Celli, B., Senn, S., Burkhart, D., Kesten, S., Menjoge, S., … UPLIFT Study Investigators, including Epton, M. (2008). A 4-year trial of tiotropium in chronic obstructive pulmonary disease. New England Journal of Medicine, 359(15), 1543-1554. doi: 10.1056/nejmoa0805800

Young, R. P., Hopkins, R. J., Hay, B. A., Epton, M. J., Black, P. N., & Gamble, G. D. (2008). Lung cancer gene associated with COPD: Triple whammy or possible confounding effect? European Respiratory Journal, 32(5), 1158-1164. doi: 10.1183/09031936.00093908

Kingham, S., Durand, M., Harrison, J., Cavanagh, J., & Epton, M. (2008). Temporal variations in particulate exposure to wood smoke in a residential school environment. Atmospheric Environment, 42(19), 4619-4631.

Taylor, D. R., Jayaram, L., Asher, M. I., & Epton, M. J. (2008). ″As-required″ combination therapy with inhaled corticosteroids and long-acting beta-2 agonists for asthma: Current evidence and recommendations [Review article]. New Zealand Medical Journal, 121(1285). Retrieved from http://journal.nzma.org.nz/journal/121-1285/3346/content.pdf

Wickens, K., Ingham, T., Epton, M., Pattemore, P., Town, I., Fishwick, D., Crane, J., and the New Zealand Asthma and Allergy Cohort Study Group, including Duignan, M., Irvine, V., Lampshire, P., Leadbitter, P., & Siebers, R. (2008). The association of early life exposure to antibiotics and the development of asthma, eczema and atopy in a birth cohort: Confounding or causality? Clinical & Experimental Allergy, 38, 1318-1324. doi: 10.1111/j.1365-2222.2008.03024.x

Senthilmohan, S. T., Kettle, A. J., McEwan, M. J., Dummer, J., Edwards, S. J., Wilson, P. F., & Epton, M. J. (2008). Detection of monobromamine, monochloramine and dichloramine using selected ion flow tube mass spectrometry and their relevance as breath markers. Rapid Communications in Mass Spectrometry, 22(5), 677-681. doi: 10.1002/rcm.3418

Epton, M. J., Dawson, R. D., Brooks, W. M., Kingham, S., Aberkane, T., Cavanagh, J. E., Frampton, C. M., Hewitt, T., Cook, J. M., … Brown, L. (2008). The effect of ambient air pollution on respiratory health of school children: A panel study. Environmental Health, 7. doi: 10.1186/1476-069X-7-16

Conference Contribution - Published proceedings: Abstract

Camargo, Jr, C. A., Ingham, T., Wickens, K., Thadhani, R. I., Silvers, K. M., Epton, M. J., Town, G. I., … Crane, J. (2008). Cord blood 25-hydroxyvitamin D levels and risk of childhood wheeze in New Zealand. Proceedings of the American Thoracic Society International Conference. Retrieved from http://www.mindcull.com/search/?q=%22risk+of+childhood+wheeze%22&submit.x=79&submit.y=35&submit=Search

Siebers, R., Wickens, K., Lampshire, P., Ingham, T., Epton, M., Town, I., Crane, J., and the Infant Cohort Study Group. (2008). Prevalence of specific IgE sensitization among 6-year old children in New Zealand. Internal Medicine Journal. 38(Suppl. 6), (pp. A165). [Abstract]

Lampshire, P., Wickens, K., Siebers, R., Ingham, T., Epton, M., Town, I., Crane, J., the Infant Cohort Study Group. (2008). Associations of total and specific IgE between children and their mothers in New Zealand six year olds. Internal Medicine Journal. 38(Suppl. 6), (pp. A157). [Abstract]

Conference Contribution - Poster Presentation (not in published proceedings)

Camargo, Jr, C. A., Ingham, T., Wickens, K., Thadhani, R. I., Silvers, K. M., Epton, M. J., Town, G. I., … Crane, J. (2008, May). Cord blood 25-hydroxyvitamin D levels and risk of childhood wheeze in New Zealand. Poster session presented at the American Thoracic Society International Conference, Toronto, Canada.

Conference Contribution - Verbal presentation and other Conference outputs

Epton, M. (2008, November). Breath analysis for biomarkers of disease. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.

2007

Journal - Research Article

Sabel, C. E., Wilson, J. G., Kingham, S., Tisch, C., & Epton, M. (2007). Spatial implications of covariate adjustment on patterns of risk: Respiratory hospital admissions in Christchurch, New Zealand. Social Science & Medicine, 65, 43-59. doi: 10.1016/j.socscimed.2007.02.040

Cavanagh, J.-A. E., Brown, L., Trought, K., Kingham, S., & Epton, M. J. (2007). Elevated concentrations of 1-hydroxypyrene in schoolchildren during winter in Christchurch, New Zealand. Science of the Total Environment, 374, 51-59. doi: 10.1016/j.scitotenv.2006.11.042

Epton, M. J., Town, G. I., Ingham, T., Wickens, K., Fishwick, D., Crane, J., and the New Zealand Asthma and Allergy Cohort Study Group, including Duignan, M., Fitzharris, P., … Lampshire, P., Leadbitter, P., Nicholson, A., Pattemore, P., Siebers, R., Silvers, K. M., & Withell, K. (2007). The New Zealand Asthma and Allergy Cohort Study (NZA²CS): Assembly, demographics and investigations. BMC Public Health, 7, 26. doi: 10.1186/1471-2458-7-26

Journal - Research Other

Silvers, K. M., Epton, M. J., & Frampton, C. M. (2007). Study was not designed to test the hypothesis [Letter]. BMJ, 335, 899. doi: 10.1136/bmj.39381.395197.BE

Conference Contribution - Published proceedings: Abstract

Siebers, R., Wickens, K., Parkes, A., Epton, M., Town, I., & Crane, J. (2007). Beta-glucan exposure and allergic disease in infancy. World Allergy Organization Journal. (November), (pp. S12). [Abstract]

Silvers, K. M., Frampton, C. M., Wickens, K., Epton, M. J., Ingham, T., Crane, J., Town, G. I., and the New Zealand Infant Cohort Study Group. (2007). Longer duration of breast feeding protects against asthma at 15 months. American Journal of Respiratory & Critical Care Medicine, 175, (pp. A273). [Abstract]

Conference Contribution - Poster Presentation (not in published proceedings)

Silvers, K. M., Frampton, C. M., Wickens, K., Epton, M. J., Ingham, T., Crane, J., Town, G. I., and the New Zealand Infant Cohort Study Group. (2007, March). Longer duration of breast feeding protects against asthma at 15 months. Poster session presented at the Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Auckland, New Zealand.

Silvers, K. M., Frampton, C. M., Wickens, K., Epton, M. J., Ingham, T., Crane, J., Town, G. I., the New Zealand Infant Cohort Study Group. (2007, May). Longer duration of breast feeding protects against asthma at 15 months. Poster session presented at the American Thoracic Society International Conference, San Francisco, California.

2006

Journal - Research Article

Kingham, S., Durand, M., Aberkane, T., Harrison, J., Wilson, J. G., & Epton, M. (2006). Winter comparison of TEOM, MiniVol and DustTrak PM₁₀ monitors in a woodsmoke environment. Atmospheric Environment, 40, 338-347.

Brooks, W. M., Lash, H., Kettle, A. J., & Epton, M. J. (2006). Optimising hydrogen peroxide measurement in exhaled breath condensate. Redox Report, 11(2), 78-84.

Kelly, M. G., Frizelle, F. A., Thornley, P. T., Beckert, L., Epton, M., & Lynch, A. C. (2006). Inflammatory bowel disease and the lung: Is there a link between surgery and bronchiectasis? International Journal of Colorectal Disease, 21(8), 754-757.

Gillespie, J., Wickens, K., Siebers, R., Howden-Chapman, P., Town, I., Epton, M., Fitzharris, P., … Crane, J., and the New Zealand Asthma and Allergy Birth Cohort Study Group, including Ingham, T., Irvine, V., Lampshire, P., Leadbitter, P., & Silvers, K. M. (2006). Endotoxin exposure, wheezing, and rash in infancy in a New Zealand birth cohort. Journal of Allergy & Clinical Immunology, 118, 1265-1270. doi: 10.1016/j.jaci.2006.07.051

McGeoch, G. R. B., Willsman, K. J., Dowson, C. A., Town, G. I., Frampton, C. M., McCartin, F. J., Cook, J. M., & Epton, M. J. (2006). Self-management plans in the primary care of patients with chronic obstructive pulmonary disease. Respirology, 11, 611-618.

Journal - Professional & Other Non-Research Articles

Mangin (Richards), D., Toop, L. J., Epton, M. J., McGeoch, G. R. B., Town, G. I., Wynn-Thomas, S. M., Dawson, R. D., Hlavac, M. C., Werno, A. M., & Abernethy, P. D. (2006). [In Reply]. Medical Journal of Australia, 184(3), 143.

Conference Contribution - Published proceedings: Abstract

Siebers, R., Wickens, K., Parkes, A., Epton, M., Town, G., Crane, J., for the Infant Cohort Study Group. (2006). Beta-glucan exposure and allergic disease in infancy. Internal Medicine Journal, 36(Suppl. 6), (pp. A209). doi: 10.1111/j.1445-5994.2006.01273.x

Wickens, K., Town, I., Epton, M., & Crane, J. (2006). Antibiotic use and the development of asthma in a New Zealand birth cohort. European Respiratory Journal. (pp. 528s). Retrieved from http://www.ersnet.org/learning_resources_player/abstract_print_06/main_frameset.htm

2005

Journal - Research Article

Richards, D. A., Toop, L. J., Epton, M. J., McGeoch, G. R. B., Town, G. I., Wynn-Thomas, S. M. H., Dawson, R. D., Hlavac, M. C., Werno, A. M., & Abernethy, P. D. (2005). Home management of mild to moderately severe community-acquired pneumonia: A randomised controlled trial. Medical Journal of Australia, 183(5), 235-238.

Taylor, D. R., Epton, M. J., Kennedy, M. A., Smith, A. D., Iles, S., Miller, A. L., Littlejohn, M. D., Cowan, J. O., Hewitt, T., Swanney, M. P., Brassett, K. P., & Herbison, G. P. (2005). Bronchodilator response in relation to β2-adrenoceptor haplotype in patients with asthma. American Journal of Respiratory & Critical Care Medicine, 172(6), 700-703.

Conference Contribution - Poster Presentation (not in published proceedings)

Epton, M. J., Wynn, B., & Frampton, C. (2005, May). Parental assessment of asthma severity in children: Effects on health care utilisation and management. Poster session presented at the International Conference of the American Thoracic Society, San Diego, USA.

Commissioned Report for External Body

Fisher, G., Kjellstrom, T., Woodward, A., Hales, S. E., Town, G. I., Sturman, A. P., … O'Dea, D., … Epton, M., … Spronken-Smith, R. A., … Dawson, R., … Donnelly, P. D. (2005). Health and air pollution in New Zealand: Christchurch pilot study. Commissioned by Health Research Council, Ministry for the Environment & Ministry of Transport. New Zealand: National Institute of Water and Atmospheric Research.

2004

Journal - Research Article

Malainual, N., Hales, B. J., Epton, M. J., Smith, W.-A., & Thomas, W. R. (2004). T-cell responses to the allergens of the house dust mite. Allergy & Clinical Immunology International, Suppl. 1, 51-54.

Conference Contribution - Published proceedings: Abstract

Richards, D. A., Toop, L. J., Epton, M., Town, I., Wynn-Thomas, S., McGeoch, G., … Murdoch, D., Than, M., & Bone, J. (2004). From whence it came: Community vs hospital care of community acquired pneumonia. Primary Care Respiratory Journal, 13(2), ABS058, (pp. 114). doi: 10.1016/j.pcrj.2004.02.001

2003

Journal - Research Article

Iles, S., Hodges, A. M., Darley, J. R., Frampton, C. M., Epton, M. J., Beckert, L. E. L., & Town, G. I. (2003). Clinical experience and pre-test probability scores in the diagnosis of pulmonary embolism. QJM, 96, 211-215.

2002

Journal - Research Article

Epton, M. J., Hales, B. J., Thompson, P. J., & Thomas, W. R. (2002). T cell cytokine responses to outer membrane proteins of Haemophilus influenzae and the house dust mite allergens Der p 1 in allergic and non-allergic subjects. Clinical & Experimental Allergy, 32(11), 1589-1595.

Epton, M. J., Smith, W., Hales, B. J., Halzell, L., Thompson, P. J., & Thomas, W. R. (2002). Non-allergenic antigen in allergic sensitization: Responses to the mite ferritin heavy chain antigen by allergic and non-allergic subjects. Clinical & Experimental Allergy, 32(9), 1341-1347.

Conference Contribution - Published proceedings: Abstract

Iles, S., Hodges, A. M., Beckert, L. E. L., Darley, J., Epton, M. J., & Town, G. I. (2002). Clinical experience does not affect pre-test clinical probability scores used to exclude pulmonary embolism. European Respiratory Journal. 20(supplement 38), (pp. 238s). Stockholm: The Journal of the European Respiratory Society. [Abstract]

2001

Journal - Research Article

Epton, M. J., Dilworth, R. J., Smith, W., & Thomas, W. R. (2001). Sensitisation to the lipid-binding apolopohorin allergen Der p 14 and the peptide Mag-1. International Archives of Allergy & Immunology, 124(1-3), 57-60.

2000

Journal - Research Article

Everts, R. J., Murdoch, D. R., Chambers, S. T., Town, G. I., Withington, S. G., Martin, I. R., Epton, M. J., Frampton, C. M., … Schousboe, M. (2000). Nosocomial pneumonia in adult general medical and surgical patients at Christchurch Hospital. New Zealand Medical Journal, 113, 221-224.

1999

Journal - Research Article

Epton, M. J., Dilworth, R. J., Smith, W., Hart, B. J., & Thomas, W. R. (1999). High-molecular-weight allergens of the house dust mite: An apolipophorin-like cDNA has sequence identity with the major M-177 allergen and the IgE-binding peptide fragments Mag1 and Mag3. International Archives of Allergy & Immunology, 120(3), 185-191.

1997

Journal - Research Article

Epton, M. J., Martin, I. R., Graham, P. J., Healy, P. E., Smith, H., Rengasamy, B., … Town, G. I. (1997). Climate and aeroallergen levels in asthma: a 12 month prospective study. Thorax, 52(6), 528-534.

1996

Journal - Research Article

Neill, A. M., Martin, I. R., Weir, R., Anderson, R., Chereshsky, A. Y., Epton, M. J., … Schousboe, M., Frampton, C. M., … Chambers, S. T., & Town, G. I. (1996). Community acquired pneumonia: aetiology and usefulness of severity criteria on admission. Thorax, 51(10), 1010-1016.

Hickling, K. G., Town, G. I., Epton, M., Neill, A., Tie, A., Whitehead, M., Graham, P., … Darlow, B. A., & Laubscher, K. (1996). Pressure limited ventilation with permisive hypercapnia and minimum PEEP in saline lavaged rabbits allows progressive improvement in oxygenation, but does not avoid ventilator induced lung injury. Intensive Care Medicine, 22(12), 1445-1452.

1994

Journal - Research Article

Neill, A. M., Epton, M. J., Martin, I. R., Drennan, C. J., & Town, G. I. (1994). An audit of the assessment and management of patients admitted to Christchurch Hospital with chronic obstructive pulmonary disease. New Zealand Medical Journal, 107(986), 365-367.