Dr Alexander Peskin graduated from Moscow State University and received his PhD and DSc (Habilitation) from the Russian Academy of Sciences. He worked as an Eleanor Roosevelt Fellow of the International Union Against Cancer at the Swiss Institute for Cancer Research (Cerutti lab) and as a Visiting Scientist at Lodz University (Bartosz lab), before joining the Centre for Free Radical Research in 1998.
Dr Peskin's expertise lies in biochemistry and enzymology, with a particular interest in thiol biochemistry. His original research focussed on superoxide dismutase and cancer, and the biochemistry of chloramines, and more recently he has been investigating the complex biochemical properties of the peroxiredoxins.
Peskin, A. V. (2023). Could CO2 be a player in a redox relay team? Redox Biochemistry & Chemistry, 5-6, 100006. doi: 10.1016/j.rbc.2023.100006
Winterbourn, C. C., Peskin, A., Kleffmann, T., Radi, R., & Pace, P. E. (2023). Carbon dioxide/bicarbonate is required for sensitive inactivation of mammalian glyceraldehyde-3-phosphate dehydrogenase by hydrogen peroxide. PNAS, 120(18), e2221047120. doi: 10.1073/pnas.2221047120
Pace, P. E., Peskin, A. V., Winterbourn, C. C., & Hampton, M. B. (2022, August). Disrupting the oligomeric structure of peroxiredoxins in cancer cells using CRISPR. Poster session presented at the CRISPR Technologies Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
Peskin, A. V., Meotti, F. C., Kean, K. M., Göbl, C., Peixoto, A. S., Pace, P. E., … Winterbourn, C. C. (2021). Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2. Journal of Biological Chemistry, 296, 100494. doi: 10.1016/j.jbc.2021.100494
Peskin, A. V., & Winterbourn, C. C. (2021). The enigma of 2-Cys peroxiredoxins: What are their roles? Biochemistry (Moscow), 86(1), 84-91. doi: 10.1134/S0006297921010089