Professor David Murdoch is the co-leader of The Infection Group, the co-director of One Health Aotearoa, a Senior Associate in the Department of International Health at Johns Hopkins School of Public Health, and a clinical microbiologist at Canterbury Health Laboratories.
Professor Murdoch served as Vice-Chancellor of the University of Otago from February 2022 to March 2023.
Research interests
David's main research interests are the epidemiology, diagnosis and prevention of respiratory tract infections, pneumococcal disease, legionellosis, bloodstream infections, and the role of vitamin D in infectious diseases.
He has a particular interest in the microbial aetiology of pneumonia, and is the Laboratory Director of the Pneumonia Etiology Research for Child Health (PERCH) project which is focused on determining the causes of severe pneumonia in young children from developing countries. David has ongoing projects based in nine countries in Africa and Asia.
PneumoNepal Study Group, Carter, M., Shrestha, S., O'Reilly, P., Gurung, P., Gurung, M., … Murdoch, D. R., … Kelly, D. F. (2023). Evaluation of acute and convalescent antibody concentration against pneumococcal capsular polysaccharides for the diagnosis of pneumococcal infection in children with community-acquired pneumonia. Pediatric Infectious Disease Journal. Advance online publication. Retrieved from https://kclpure.kcl.ac.uk/portal/en/publications/evaluation-of-acute-and-convalescent-antibody-concentration-again
Journal - Research Article
Murdoch, D., & French, N. (2023, November). Infectious diseases and pandemic preparedness. Special Seminar, University of Otago, Christchurch, New Zealand. [Research Presentation].
Other Research Output
Shaw, D., Abad, R., Amin-Chowdhury, Z., Bautista, A., Bennett, D., Broughton, K., … Murdoch, D., … Brueggemann, A. B. (2023). Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: Analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium. Lancet Digital Health. Advance online publication. doi: 10.1016/s2589-7500(23)00108-5
Journal - Research Article
Chambers, S. T., Scott-Thomas, A., Storer, M., Slow, S., Williman, J., Epton, M., Murdoch, D. R., Metcalf, S., Carr, A., Isenman, H., & Maze, M. (2023). Adjunctive intravenous then oral vitamin C for moderate and severe community-acquired pneumonia in hospitalized adults: Feasibility of randomized controlled trial. Scientific Reports, 13, 11879. doi: 10.1038/s41598-023-37934-z
Journal - Research Article
Jun, H., Scott-Thomas, A., Slow, S., Williman, J., Murdoch, D. R., & Chambers, S. T. (2023). The inhibitory effect of copper, zinc, and manganese on Legionella longbeachae and other Legionella spp. in vitro. Letters in Applied Microbiology, 76, 1-9. doi: 10.1093/lambio/ovad074
Journal - Research Article
Cheung, J., Nordmeier, K., Kelland, S., Harrington, M., Williman, J., Storer, M., Beaglehole, B., Beckert, L., Chambers, S. T., Epton, M. J., Freeman, J., Murdoch, D. R., Werno, A. M., & Maze, M. J. (2023). Symptom persistence and recovery among COVID-19 survivors during a limited outbreak in Canterbury, New Zealand: A prospective cohort study. Internal Medicine Journal, 53, 37-45. doi: 10.1111/imj.15930
Journal - Research Article
Bryce, A., Foley, L., Phillipson, J., Slow, S., Storer, M., Williman, J., Beasley, R., Bhally, H., … Dummer, J., Epton, M., … Gracie, K., Hancox, R. J., Hills, T., Hogg, S., … Kearns, N., … Murdoch, D., Raymond, N., … Maze, M. J. (2022). Clinical features of patients hospitalised with COVID-19 from February to October 2020, during the early waves of the pandemic in New Zealand. New Zealand Medical Journal, 135(1552), 120-130. Retrieved from https://journal.nzma.org.nz/
Journal - Research Article
Carter, M. J., Gurung, M., Pokhrel, B., Bijukchhe, S. M., Karmacharya, S., Khadka, B., … Murdoch, D. R., … Pollard, A. J. (2022). Childhood invasive bacterial disease in Kathmandu Nepal (2005-2013). Pediatric Infectious Disease Journal, 41(3), 192-198. doi: 10.1097/inf.0000000000003421
Journal - Research Article
Kandasamy, R., Lo, S., Gurung, M., Carter, M. J., Gladstone, R., Lees, J., … Murdoch, D. R., … Pollard, A. J. (2022). Effect of childhood vaccination and antibiotic use on pneumococcal populations and genome-wide associations with disease among children in Nepal: An observational study. Lancet Microbe, 3, e503-e511. doi: 10.1016/S2666-5247(22)00066-0
Journal - Research Article
Park, D. E., Watson, N. L., Focht, C., Feikin, D., Hammitt, L., Brooks, W. A., … Murdoch, D. R., … McCollum, E. D. (2022). Digitally recorded and remotely classified lung auscultation compared with conventional stethoscope classifications among children aged 1-59 months enrolled in the Pneumonia Etiology Research for Child Health (PERCH) case-control study. BMJ Open Respiratory Research, 9, e001144. doi: 10.1136/bmjresp-2021-001144
Journal - Research Article
Shrestha, S., Gurung, M., Amatya, P., Bijukchhe, S., Bose, A. S., Carter, M. J., … Murdoch, D. R., … & the PneumoNepal Study Group. (2022). Effect of the of 10-valent pneumococcal conjugate vaccine in Nepal 4 years after introduction: An observational cohort study. Lancet Global Health, 10, e1494-e1504. doi: 10.1016/S2214-109X(22)00281-9
Journal - Research Article
Slow, S., Anderson, T., Murdoch, D. R., Bloomfield, S., Winter, D., & Biggs, P. J. (2022). Extensive epigenetic modification with large-scale chromosomal and plasmid recombination characterise the Legionella longbeachae serogroup 1 genome. Scientific Reports, 12, 5810. doi: 10.1038/s41598-022-09721-9
Journal - Research Article
Téllez, A., Ambrosioni, J., Hernández-Meneses, M., Llopis, J., Ripa, M., Chambers, S. T., … Raymond, N., … the International Collaboration on Endocarditis (ICE) Investigators, including Murdoch, D. R. (2022). Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci. Journal of Infection, 85, 137-146. doi: 10.1016/j.jinf.2022.05.023
Journal - Research Article
Awori, J. O., Kamau, A., Morpeth, S., Kazungu, S., Silaba, M., Sande, J., … Murdoch, D. R., … Scott, J. A. G. (2021). The etiology of pneumonia in HIV-uninfected Children in Kilifi, Kenya: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S29-S39. doi: 10.1097/inf.0000000000002653
Journal - Research Article
Baillie, V. L., Moore, D. P., Muthunjwa, A., Baggett, H. C., Brooks, A., Feikin, D. R., … Murdoch, D. R., … Madhi, S. A. (2021). Epidemiology of the rhinovirus (RV) in African and Southeast Asian children: A case-control pneumonia etiology study. Viruses, 13(7), 1249. doi: 10.3390/v13071249
Journal - Research Article
Bothara, R. K., Tafuna'i, M., Wilkinson, T. J., Desrosiers, J., Jack, S., Pattemore, P. K., Walls, T., Sopoaga, F., Murdoch, D. R., & Miller, A. P. (2021). Global health classroom: Mixed methods evaluation of an interinstitutional model for reciprocal global health learning among Samoan and New Zealand medical students. Globalization & Health, 17, 99. doi: 10.1186/s12992-021-00755-8
Journal - Research Article
Brooks, W. A., Zaman, K., Goswami, D., Prosperi, C., Endtz, H. P., Hossain, L., … Murdoch, D. R., … Deloria Knoll, M. (2021). The etiology of childhood pneumonia in Bangladesh: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S79-S90. doi: 10.1097/inf.0000000000002648
Journal - Research Article
Brueggemann, A. B., Jansen van Rensburg, M. J., Shaw, D., Jolley, K. A., McCarthy, N. D., Maiden, M. C. J., … Murdoch, D. R., … Zhou, F. (2021). Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and territories in the Invasive Respiratory Infection Surveillance Initiative: A prospective analysis of surveillance data. Lancet Digital Health, 3(6), e360-e370. doi: 10.1016/S2589-7500(21)00077-7
Journal - Research Article
Bunthi, C., Rhodes, J., Thamthitiwat, S., Higdon, M. M., Chuananon, S., Amorninthapichet, T., … Murdoch, D. R., … Akarasewi, P. (2021). Etiology and clinical characteristics of severe pneumonia among young children in Thailand: Pneumonia Etiology Research for Child Health (PERCH) case-control study findings, 2012-2013. Pediatric Infectious Disease Journal, 40, S91-S100. doi: 10.1097/inf.0000000000002768
Journal - Research Article
Chambers, S. T., Withers, A., Dawson, K., Anderson, T., Williman, J., Murdoch, D., Scott-Thomas, A., & Slow, S. (2021). How safe are gloves and masks used for protection against Legionella longbeachae infection when gardening? Letters in Applied Microbiology, 73, 616-622. doi: 10.1111/lam.13546
Journal - Research Article
Deloria Knoll, M., Prosperi, C., Baggett, H. C., Brooks, W. A., Feikin, D. R., Hammitt, L. L., … Murdoch, D. R., … O'Brien, K. L. (2021). Introduction to the site-specific etiologic results from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S1-S6. doi: 10.1097/inf.0000000000002778
Journal - Research Article
Ebruke, B. E., Deloria Knoll, M., Haddix, M., Zaman, S. M. A., Prosperi, C., Feikin, D. R., … Murdoch, D. R., … Howie, S. R. C. (2021). The aetiology of pneumonia from analysis of lung aspirate and pleural fluid samples: Findings from the PERCH study. Clinical Infectious Diseases, 73, e3788-e3796. doi: 10.1093/cid/ciaa1032
Journal - Research Article
Geoghegan, J. L., Douglas, J., Ren, X., Storey, M., Hadfield, J., Silander, O. K., … Baker, M. G., Murdoch, D. R., … de Ligt, J. (2021). Use of genomics to track Coronavirus disease outbreaks, New Zealand. Emerging Infectious Diseases, 27(5), 1317-1322. doi: 10.3201/eid2705.204579
Journal - Research Article
Howie, S. R. C., Ebruke, B. E., McLellan, J. L., Deloria Knoll, M., Dione, M. M., Feikin, D. R., … Murdoch, D. R., … Zaman, S. M. A. (2021). The etiology of childhood Pneumonia in The Gambia: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S7-S17. doi: 10.1097/inf.0000000000002766
Journal - Research Article
Jolliffe, D. A., Camargo, Jr, C. A., Sluyter, J. D., Aglipay, M., Aloia, J. F., Ganmaa, D., … Murdoch, D. R., … Martineau, A. R. (2021). Vitamin D supplementation to prevent acute respiratory infections: A systematic review and meta-analysis of aggregate data from randomised controlled trials. Lancet Diabetes & Endocrinology, 9, 276-292. doi: 10.1016/S2213-8587(21)00051-6
Journal - Research Article
Mohammadi, A., Chambers, S. T., Slow, S., Anderson, T., Williman, J., Scott, P., Murdoch, D., & Scott-Thomas, A. (2021). Presence of Legionella Longbeachae in pine but not composted green waste used in manufacture of potting soils in New Zealand. Journal of Applied & Environmental Microbiology, 9(1), 1-4. doi: 10.12691/jaem-9-1-1
Journal - Research Article
Moore, D. P., Baillie, V. L., Mudau, A., Wadula, J., Adams, T., Mangera, S., … Murdoch, D. R., … Madhi, S. A. (2021). The etiology of pneumonia in HIV-1-infected South African children in the era of antiretroviral treatment: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S69-S78. doi: 10.1097/inf.0000000000002651
Journal - Research Article
Moore, D. P., Baillie, V. L., Mudau, A., Wadula, J., Adams, T., Mangera, S., … Murdoch, D. R., … Madhi, S. A. (2021). The etiology of pneumonia in HIV-uninfected South African children: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S59-S68. doi: 10.1097/inf.0000000000002650
Journal - Research Article
Mwananyanda, L., Thea, D. M., Chipeta, J., Kwenda, G., Mulindwa, J. M., Mwenechanya, M., … Murdoch, D. R., … Seidenberg, P. (2021). The etiology of pneumonia in Zambian children: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S40-S49. doi: 10.1097/inf.0000000000002652
Journal - Research Article
Nguyen, T., Adnan, M., Nguyen, B. P., de Ligt, J., Geoghegan, J. L., Dean, R., … Baker, M. G., … Murdoch, D. R., … Simpson, C. R. (2021). COVID-19 vaccine strategies for Aotearoa New Zealand: A mathematical modelling study. Lancet Regional Health: Western Pacific, 15, 100256. doi: 10.1016/j.lanwpc.2021.100256
Journal - Research Article
Park, D. E., Higdon, M. M., Prosperi, C., Baggett, H. C., Brooks, W. A., Feikin, D. R., … Murdoch, D. R., … Deloria Knoll, M. (2021). Upper respiratory tract co-detection of human endemic coronaviruses and high-density pneumococcus associated with increased severity among HIV-uninfected children under 5 years old in the PERCH study. Pediatric Infectious Disease Journal, 40(6), 503-512. doi: 10.1097/inf.0000000000003139
Journal - Research Article
Pericàs, J. M., Llopis, J., Athan, E., Hernández-Meneses, M., Hannan, M. M., Murdoch, D. R., … on behalf of the International Collaboration on Endocarditis (ICE) Investigators. (2021). Prospective cohort study of infective endocarditis in people who inject drugs. Journal of the American College of Cardiology, 77(5), 544-555. doi: 10.1016/j.jacc.2020.11.062
Journal - Research Article
Scott, P., Zhang, J., Anderson, T., Priest, P. C., Chambers, S., Smith, H., Murdoch, D. R., French, N., & Biggs, P. J. (2021). Whole-genome sequencing and ad hoc shared genome analysis of Staphylococcus aureus isolates from a New Zealand primary school. Scientific Reports, 11(1), 20328. doi: 10.1038/s41598-021-99080-8
Journal - Research Article
Seidenberg, P., Mwananyanda, L., Chipeta, J., Kwenda, G., Mulindwa, J. M., Mwansa, J., … Murdoch, D. R., … Thea, D. M. (2021). The etiology of pneumonia in HIV-infected Zambian children: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S50-S58. doi: 10.1097/inf.0000000000002649
Journal - Research Article
Shrestha, S., Stockdale, L. K., Gautam, M. C., Gurung, M., Feng, S., Maskey, P., … Murdoch, D. R., … Pollard, A. J. (2021). Impact of vaccination on Haemophilus influenzae type b carriage in healthy children less than 5 years of age in an urban population in Nepal. Journal of Infectious Diseases, 224(Suppl. 3), S267-S274. doi: 10.1093/infdis/jiab072
Journal - Research Article
Tapia, M. D., Sylla, M., Driscoll, A. J., Touré, A., Kourouma, N., Sissoko, S., … Murdoch, D. R., … Kotloff, K. L. (2021). The etiology of childhood pneumonia in Mali: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S18-S28. doi: 10.1097/inf.0000000000002767
Journal - Research Article
Carter, M. J., Gurung, P., Jones, C., Rajkarnikar, S., Kandasamy, R., Gurung, M., … Murdoch, D. R., … for the PneumoNepal Study Group. (2020). Assessment of an antibody-in-lymphocyte supernatant assay for the etiological diagnosis of pneumococcal pneumonia in children. Frontiers in Cellular & Infection Microbiology, 9, 459. doi: 10.3389/fcimb.2019.00459
Journal - Research Article
Gallagher, K. E., Deloria Knoll, M., Prosperi, C., Baggett, H. C., Brooks, W. A., Feiken, D. R., … Murdoch, D. R., … for The PERCH Study Group. (2020). The predictive performance of a pneumonia severity score in Human Immunodeficiency Virus-negative children presenting to hospital in seven low- and middle-income countries. Clinical Infectious Diseases, 70, 1050-1057. doi: 10.1093/cid/ciz350
Journal - Research Article
Geoghegan, J. L., Ren, X., Storey, M., Hadfield, J., Jelley, L., Jefferies, S., … Baker, M. G., Murdoch, D. R., … de Ligt, J. (2020). Genomic epidemiology reveals transmission patterns and dynamics of SARS-CoV-2 in Aotearoa New Zealand. Nature Communications, 11(1), 6351. doi: 10.1038/s41467-020-20235-8
Journal - Research Article
Hannaway, R. F., Wang, X., Schneider, M., Slow, S., Cowan, J., Brockway, B., Schofield, M. R., Morgan, X. C., Murdoch, D. R., & Ussher, J. E. (2020). Mucosal-associated invariant T cells and Vδ2+ γδ T cells in community acquired pneumonia: Association of abundance in sputum with clinical severity and outcome. Clinical & Experimental Immunology, 199(2), 201-215. doi: 10.1111/cei.13377
Journal - Research Article
McCollum, E. D., Park, D. E., Watson, N. L., Fancourt, N. S. S., Focht, C., Baggett, H. C., … Murdoch, D. R., … Hammitt, L. L. (2020). Digital auscultation in PERCH: Associations with chest radiography and pneumonia mortality in children. Pediatric Pulmonology, 55, 3197-3208. doi: 10.1002/ppul.25046
Journal - Research Article
Mohammadi, A., Chambers, S. T., Scott-Thomas, A., Lewis, J. G., Anderson, T., Podmore, R., Williman, J., Murdoch, D., & Slow, S. (2020). Enhancement of culture of Legionella longbeachae from respiratory samples using immunomagnetic separation and antimicrobial decontamination. Journal of Clinical Microbiology, 58(11), e01218-20. doi: 10.1128/jcm.01218-20
Journal - Research Article
Slow, S., Pearson, J. F., Florkowski, C. M., Elder, P. A., Lewis, J. G., Kennedy, M. A., & Murdoch, D. R. (2020). Effect of genetic factors on the response to vitamin D3 supplementation in the VIDARIS randomised controlled trial. Nutrition, 75-76, 110761. doi: 10.1016/j.nut.2020.110761
Journal - Research Article
Murdoch, D. R., Werno, A. M., & Jennings, L. C. (2019). Microbiological diagnosis of respiratory illness: Recent advances. In R. Wilmott, A. Bush, R. Deterding, F. Ratjen, P. Sly, H. Zar & H. Li (Eds.), Kendig's disorders of the respiratory tract in children. (9 ed.) (pp. 396-405.e3). Philadelphia, PA: Elsevier. doi: 10.1016/B978-0-323-44887-1.00022-5
Chapter in Book - Research
Kandasamy, R., Gurung, M., Thorson, S., Yu, L.-M., Galal, U., Voysey, M., … Murdoch, D. R., … Pollard, A. J. (2019). Comparison of two schedules of two-dose priming with the ten-valent pneumococcal conjugate vaccine in Nepalese children: An open-label, randomised non-inferiority controlled trial. Lancet Infectious Diseases, 19, 156-164. doi: 10.1016/s1473-3099(18)30568-1
Journal - Research Article
Martineau, A. R., Jolliffe, D. A., Greenberg, L., Aloia, J. F., Bergman, P., Dubnoz-Raz, G., … Murdoch, D. R., … Hooper, R. L. (2019). Vitamin D supplementation to prevent acute respiratory infections: Individual participant data meta-analysis. Health Technology Assessment, 23(2). doi: 10.3310/hta23020
Journal - Research Article
Oo, K. M., Myat, T. O., Htike, W. W., Biswas, A., Hannaway, R. F., Murdoch, D. R., Crump, J. A., & Ussher, J. E. (2019). Molecular mechanisms of antimicrobial resistance and phylogenetic relationships of Salmonella enterica isolates from febrile patients in Yangon, Myanmar. Transactions of the Royal Society of Tropical Medicine & Hygiene, 113, 641-648. doi: 10.1093/trstmh/trz053
Journal - Research Article
Oo, W. T., Myat, T. O., Htike, W. W., Ussher, J. E., Murdoch, D. R., Lwin, K. T., … Maze, M. J., … Crump, J. A. (2019). Incidence of typhoid and paratyphoid fevers among adolescents and adults in Yangon, Myanmar. Clinical Infectious Diseases, 68(Suppl. 2), S124-S129. doi: 10.1093/cid/ciy1109
Journal - Research Article
Priest, P. C., Slow, S., Chambers, S. T., Cameron, C. M., Balm, M. N., Beale, M. W., Blackmore, T. K., … Ussher, J. E., van der Linden, A. J., … Murdoch, D. R. (2019). The burden of Legionnaires' disease in New Zealand (LegiNZ): A national surveillance study. Lancet Infectious Diseases, 19, 770-777. doi: 10.1016/S1473-3099(19)30113-6
Journal - Research Article
The Pneumonia Etiology Research for Child Health (PERCH) Study Group, including Murdoch, D. R., & Anderson, T. P. (2019). Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: The PERCH multi-country case-control study. Lancet, 394(10200), 757-779. doi: 10.1016/S0140-6736(19)30721-4
Journal - Research Article
Britto, C. D., Dyson, Z. A., Duchene, S., Carter, M. J., Gurung, M., Kelly, D. F., Murdoch, D. R., … Pollard, A. J. (2018). Laboratory and molecular surveillance of paediatric typhoidal Salmonella in Nepal: Antimicrobial resistance and implications for vaccine policy. PLoS Neglected Tropical Diseases, 12(4), e0006408. doi: 10.1371/journal.pntd.0006408
Journal - Research Article
Coker, M. S., Forbes, L. V., Plowman-Holmes, M., Murdoch, D. R., Winterbourn, C. C., & Kettle, A. J. (2018). Interactions of staphyloxanthin and enterobactin with myeloperoxidase and reactive chlorine species. Archives of Biochemistry & Biophysics, 646, 80-89. doi: 10.1016/j.abb.2018.03.039
Journal - Research Article
Morpeth, S. C., Munywoki, P., Hammitt, L. L., Bett, A., Bottomley, C., Onyango, C. O., Murdoch, D. R., … Scott, J. A. G. (2018). Impact of viral upper respiratory tract infection on the concentration of nasopharyngeal pneumococcal carriage among Kenyan children. Scientific Reports, 8, 11030. doi: 10.1038/s41598-018-29119-w
Journal - Research Article
Scott, P., Priest, P. C., Chambers, S. T., Heijne, J. C. M., & Murdoch, D. R. (2018). Staphylococcus aureus carriage in a New Zealand primary school: A cohort study. Pediatric Infectious Disease Journal, 37(6), e172-e175. doi: 10.1097/inf.0000000000001796
Journal - Research Article
Slow, S., Epton, M., Storer, M., Thiessen, R., Lim, S., Wong, J., Chin, P., Tovaranonte, P., Pearson, J., Chambers, S. T., Murdoch, D. R., and VIDCAPS Group, including Jardine, D., & Pithie, A. (2018). Effect of adjunctive single high-dose vitamin D3 on outcome of community-acquired pneumonia in hospitalised adults: The VIDCAPS randomised controlled trial. Scientific Reports, 8(1), 13829. doi: 10.1038/s41598-018-32162-2
Journal - Research Article
Baggett, H. C., Watson, N. L., Deloria Knoll, M., Brooks, W. A., Feikin, D. R., Hammitt, L. L., … Murdoch, D. R., … for the PERCH Study Group. (2017). Density of upper respiratory colonization with Streptococcus pneumoniae and its role in the diagnosis of pneumococcal pneumonia among children aged <5 years in the PERCH Study. Clinical Infectious Diseases, 64(Suppl. 3), S317-S327. doi: 10.1093/cid/cix100
Journal - Research Article
Barratt, K., Anderson, T. P., Fahey, J. A., Jennings, L. C., Werno, A. M., & Murdoch, D. R. (2017). Comparison of the fast track diagnostics respiratory 21 and Seegene Allplex multiplex polymerase chain reaction assays for the detection of respiratory viruses. British Journal of Biomedical Science, 74(2), 85-89. doi: 10.1080/09674845.2017.1278885
Journal - Research Article
Deloria Knoll, M., Fu, W., Shi, Q., Prosperi, C., Wu, Z., Hammitt, L. L., … Murdoch, D. R., … Zeger, S. L. (2017). Bayesian estimation of pneumonia etiology: Epidemiologic considerations and applications to the Pneumonia Etiology Research for Child Health Study. Clinical Infectious Diseases, 64(Suppl. 3), S213-S227. doi: 10.1093/cid/cix144
Journal - Research Article
Deloria Knoll, M., Morpeth, S. C., Scott, J. A. G., Watson, N. L., Park, D. E., Baggett, H. C., … Murdoch, D., … for the PERCH Study Group. (2017). Evaluation of pneumococcal load in blood by polymerase chain reaction for the diagnosis of pneumococcal pneumonia in young children in the PERCH Study. Clinical Infectious Diseases, 64(Suppl. 3), S357-S367. doi: 10.1093/cid/cix149
Journal - Research Article
DeLuca, A. N., Hammitt, L. L., Kim, J., Higdon, M. M., Baggett, H. C., Brooks, W. A., … Murdoch, D. R., … for the PERCH Study Group. (2017). Safety of induced sputum collection in children hospitalized with severe or very severe pneumonia. Clinical Infectious Diseases, 64(Suppl. 3), S301-S308. doi: 10.1093/cid/cix078
Journal - Research Article
Driscoll, A. J., Deloria Knoll, M., Hammitt, L. L., Baggett, H. C., Brooks, W. A., Feikin, D. R., … Murdoch, D. R., for the PERCH Study Group. (2017). The effect of antibiotic exposure and specimen volume on the detection of bacterial pathogens in children with pneumonia. Clinical Infectious Diseases, 64(Suppl. 3), S368-S377. doi: 10.1093/cid/cix101
Journal - Research Article
Driscoll, A. J., Karron, R. A., Morpeth, S. C., Bhat, N., Levine, O. S., Baggett, H. C., … Murdoch, D. R. (2017). Standardization of laboratory methods for the PERCH study. Clinical Infectious Diseases, 64(Suppl. 3), S245-S252. doi: 10.1093/cid/cix081
Journal - Research Article
Fancourt, N., Deloria Knoll, M., Baggett, H. C., Brooks, W. A., Feikin, D. R., Hammitt, L. L., … Murdoch, D. R., … for the PERCH Study Group. (2017). Chest radiograph findings in childhood pneumonia cases from the multisite PERCH study. Clinical Infectious Diseases, 64(Suppl. 3), S262-S270. doi: 10.1093/cid/cix089
Journal - Research Article
Feikin, D. R., Fu, W., Park, D. E., Shi, Q., Higdon, M. M., Baggett, H. C., … Murdoch, D. R., for the PERCH Study Group. (2017). Is higher viral load in the upper respiratory tract associated with severe pneumonia? Findings from the PERCH study. Clinical Infectious Diseases, 64(Suppl. 3), S337-S346. doi: 10.1093/cid/cix148
Journal - Research Article
Feikin, D. R., Hammitt, L. L., Murdoch, D. R., O'Brien, K. L., & Scott, J. A. G. (2017). The enduring challenge of determining pneumonia etiology in children: Considerations for future research priorities. Clinical Infectious Diseases, 64(Suppl. 3), S188-S196. doi: 10.1093/cid/cix143
Journal - Research Article
Gaddam, R. R., Chambers, S., Murdoch, D., Shaw, G., & Bhatia, M. (2017). Circulating levels of hydrogen sulfide and substance P in patients with sepsis. Journal of Infection, 75(4), 293-300. doi: 10.1016/j.jinf.2017.07.005
Journal - Research Article
Hammitt, L. L., Feikin, D. R., Scott, J. A. G., Zeger, S. L., Murdoch, D. R., O'Brien, K. L., & Deloria Knoll, M. (2017). Addressing the analytic challenges of cross-sectional pediatric pneumonia etiology data. Clinical Infectious Diseases, 64(Suppl. 3), S197-S204. doi: 10.1093/cid/cix147
Journal - Research Article
Higdon, M. M., Hammitt, L. L., Deloria Knoll, M., Baggett, H. C., Brooks, W. A., Howie, S. R. C., … Murdoch, D. R., … for the PERCH Study Group. (2017). Should controls with respiratory symptoms be excluded from case-control studies of pneumonia etiology? Reflections from the PERCH Study. Clinical Infectious Diseases, 64(Suppl. 3), S205-S212. doi: 10.1093/cid/cix076
Journal - Research Article
Higdon, M. M., Le, T., O'Brien, K. L., Murdoch, D. R., Prosperi, C., Baggett, H. C., … for the PERCH Study Group. (2017). Association of C-reactive protein with bacterial and respiratory syncytial virus-associated pneumonia among children aged <5 years in the PERCH study. Clinical Infectious Diseases, 64(Suppl. 3), S378-S386. doi: 10.1093/cid/cix150
Journal - Research Article
Kenagy, E., Priest, P. C., Cameron, C. M., Smith, D., Scott, P., Cho, V., … Murdoch, D. R. (2017). Risk factors for Legionella longbeachae Legionnaires' disease, New Zealand. Emerging Infectious Diseases, 23(7), 1148-1154. doi: 10.3201/eid2307.161429
Journal - Research Article
Martineau, A. R., Jolliffe, D. A., Hooper, R. L., Greenberg, L., Aloia, J. F., Bergman, P., … Murdoch, D. R., … Camargo, Jr, C. A. (2017). Vitamin D supplementation to prevent acute respiratory tract infections: Systematic review and meta-analysis of individual participant data. BMJ, 356, i6583. doi: 10.1136/bmj.i6583
Journal - Research Article
Moore, D. P., Higdon, M. M., Hammitt, L. L., Prosperi, C., DeLuca, A. N., Da Silva, P., … Murdoch, D. R., … Madhi, S. A. (2017). The incremental value of repeated induced sputum and gastric aspirate samples for the diagnosis of pulmonary tuberculosis in young children with acute community-acquired pneumonia. Clinical Infectious Diseases, 64(Suppl. 3), S309-S316. doi: 10.1093/cid/cix099
Journal - Research Article
Morpeth, S. C., Deloria Knoll, M., Scott, J. A. G., Park, D. E., Watson, N. L., Baggett, H. C., … Murdoch, D., for the PERCH Study Group. (2017). Detection of pneumococcal DNA in blood by polymerase chain reaction for diagnosing pneumococcal pneumonia in young children from low- and middle-income countries. Clinical Infectious Diseases, 64(Suppl. 3), S347-S356. doi: 10.1093/cid/cix145
Journal - Research Article
Murdoch, D. R., Morpeth, S. C., Hammitt, L. L., Driscoll, A. J., Watson, N. L., Baggett, H. C., … for the PERCH Study Group. (2017). Microscopic analysis and quality assessment of induced sputum from children with pneumonia in the PERCH Study. Clinical Infectious Diseases, 64(Suppl. 3), S271-S279. doi: 10.1093/cid/cix083
Journal - Research Article
Murdoch, D. R., Morpeth, S. C., Hammitt, L. L., Driscoll, A. J., Watson, N. L., Baggett, H. C., … for the PERCH Study Group. (2017). The diagnostic utility of induced sputum microscopy and culture in childhood pneumonia. Clinical Infectious Diseases, 64(Suppl. 3), S280-S288. doi: 10.1093/cid/cix090
Journal - Research Article
Myat, T. O., Hannaway, R. F., Zin, K. N., Htike, W. W., Win, K. K., Crump, J. A., Murdoch, D. R., & Ussher, J. E. (2017). ESBL- and carbapenemase-producing Enterobacteriaceae in patients with bacteremia, Yangon, Myanmar, 2014. Emerging Infectious Diseases, 23(5), 857-859. doi: 10.3201/eid2305.161100
Journal - Research Article
O'Brien, K. L., Baggett, H. C., Brooks, W. A., Feikin, D. R., Hammitt, L. L., Howie, S. R. C., … Murdoch, D. R., … Zeger, S. L. (2017). Introduction to the epidemiologic considerations, analytic methods, and foundational results from the pneumonia etiology research for child health study. Clinical Infectious Diseases, 64(Suppl. 3), S179-S184. doi: 10.1093/cid/cix142
Journal - Research Article
Park, D. E., Baggett, H. C., Howie, S. R. C., Shi, Q., Watson, N. L., Brooks, W. A., … Murdoch, D. R., … for the PERCH Study Group. (2017). Colonization density of the upper respiratory tract as a predictor of pneumonia: Haemophilus influenzae, Moraxella catarrhalis, Staphylococcus aureus, and Pneumocystis jirovecii. Clinical Infectious Diseases, 64(Suppl. 3), S328-S336. doi: 10.1093/cid/cix104
Journal - Research Article
Shi, T., McAllister, D. A., O'Brien, K. L., Simoes, E. A. F., Madhi, S. A., Gessner, B. D., … for the RSV Global Epidemiology Network, including Murdoch, D. (2017). Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: A systematic review and modelling study. Lancet, 390, 946-958. doi: 10.1016/S0140-6736(17)30938-8
Journal - Research Article
Slow, S., Anderson, T., Miller, J., Singh, S., Murdoch, D., & Biggs, P. J. (2017). Complete genome sequence of a Legionella longbeachae Serogroup 1 strain isolated from a patient with Legionnaires' disease. Genome Announcements, 5(24), e00564-17. doi: 10.1128/genomeA.00564-17
Journal - Research Article
Thea, D. M., Seidenberg, P., Park, D. E., Mwananyanda, L., Fu, W., Shi, Q., … Murdoch, D. R., … for the PERCH Study Group. (2017). Limited utility of polymerase chain reaction in induced sputum specimens for determining the causes of childhood pneumonia in resource-poor settings: Findings from the Pneumonia Etiology Research for Child Health (PERCH) study. Clinical Infectious Diseases, 64(Suppl. 3), S289-S300. doi: 10.1093/cid/cix098
Journal - Research Article
Watson, N. L., Prosperi, C., Driscoll, A. J., Higdon, M. M., Park, D. E., Sanza, M., … Murdoch, D. R., … Deloria Knoll, M. (2017). Data management and data quality in PERCH, a large international case-control study of severe childhood pneumonia. Clinical Infectious Diseases, 64(Suppl. 3), S238-S244. doi: 10.1093/cid/cix080
Journal - Research Article
Barger-Kamate, B., Deloria Knoll, M., Kagucia, E. W., Prosperi, C., Baggett, H. C., Brooks, W. A., … Murdoch, D. R., … for the Pneumonia Etiology Research for Child Health (PERCH) Study Group. (2016). Pertussis-associated pneumonia in infants and children from low- and middle-income countries participating in the PERCH study. Clinical Infectious Diseases, 63(Suppl. 4), S187-S196. doi: 10.1093/cid/ciw546
Journal - Research Article
Best, E. J., Walls, T., Souter, M., Neeff, M., Anderson, T., Salkeld, L., … Murdoch, D., & Mills, N. (2016). Pneumococcal vaccine impact on otitis media microbiology: A New Zealand cohort study before and after the introduction of PHiD-CV10 vaccine. Vaccine, 34(33), 3840-3847. doi: 10.1016/j.vaccine.2016.05.041
Journal - Research Article
Carugati, M., Petti, C. A., Arnold, C., Miro, J. M., Pericàs, J., Garcia de la Maria, C., … Murdoch, D., … Chu, V. H. (2016). Antistaphylococcal β-lactams versus vancomycin for the treatment of infective endocarditis due to methicllin-susceptible coagulase-negative staphylococci: A prospective cohort study from the International Collaboration on Endocarditis (ICE). Antimicrobial Agents & Chemotherapy, 60(10), 6341-6349. doi: 10.1128/aac.01531-16
Journal - Research Article
Isenman, H. L., Chambers, S. T., Pithie, A. D., MacDonald, S. L. S., Hegarty, J. M., Fenwick, J. L., Maze, M. J., Metcalf, S. C. L., & Murdoch, D. R. (2016). Legionnaires' disease caused by Legionella longbeachae: Clinical features and outcomes of 107 cases from an endemic area. Respirology, 21(7), 1292-1299. doi: 10.1111/resp.12808
Journal - Research Article
Murdoch, D. R. (2016). How recent advances in molecular tests could impact the diagnosis of pneumonia. Expert Review of Molecular Diagnostics, 16(5), 533-540. doi: 10.1586/14737159.2016.1156536
Journal - Research Article
Arnold, C. J., Johnson, M., Bayer, A. S., Bradley, S., Giannitsioti, E., Miró, J. M., … for the ICE Investigators, including Chambers, S., Raymond, N., & Murdoch, D. R. (2015). Candida infective endocarditis: An observational cohort study with a focus on therapy. Antimicrobial Agents & Chemotherapy, 59(4), 2365-2373. doi: 10.1128/AAC.04867-14
Journal - Research Article
Hamaluba, M., Kandasamy, R., Upreti, S. R., Subedi, G. R., Shrestha, S., Bhattarai, S., … Murdoch, D. R., … Pollard, A. J. (2015). Comparison of two-dose priming plus 9-month booster with a standard three-dose priming schedule for a ten-valent pneumococcal conjugate vaccine in Nepalese infants: A randomised, controlled, open-label, non-inferiority trial. Lancet Infectious Diseases, 15(4), 405-414. doi: 10.1016/s1473-3099(15)70007-1
Journal - Research Article
Kandasamy, R., Gurung, M., Thapa, A., Ndimah, S., Adhikari, N., Murdoch, D. R., … Pollard, A. J. (2015). Multi-serotype pneumococcal nasopharyngeal carriage prevalence in vaccine naïve Nepalese children, assessed using molecular serotyping. PLoS ONE, 10(2), e0114286. doi: 10.1371/journal.pone.0114286
Journal - Research Article
Mills, N., Best, E. J., Murdoch, D., Souter, M., Neeff, M., Anderson, T. P., … Walls, T. (2015). What is behind the ear drum? The microbiology of otitis media and the nasopharyngeal flora in children in the era of pneumococcal vaccination. Journal of Paediatrics & Child Health, 51(3), 300-306. doi: 10.1111/jpc.12710
Journal - Research Article
Prasad, N., Murdoch, D. R., Reyburn, H., & Crump, J. A. (2015). Etiology of severe febrile illness in low- and middle-income countries: A systematic review. PLoS ONE, 10(6), e0127962. doi: 10.1371/journal.pone.0127962
Journal - Research Article
Murdoch, D. R. (2005). Streptococcus pneumoniae. In J. Fuchs & M. Podda (Eds.), Encyclopedia of diagnostic genomics and proteomics. (pp. 1236-1240). New York: Marcel Dekker.
Chapter in Book - Research
Pollard, A. J., & Murdoch, D. R. (2003). The high altitude medicine handbook (3rd ed.). Oxon, UK: Radcliffe Medical Press, 193p.
Authored Book - Other
Pollard, A. J., & Murdoch, D. R. (2001). Travel Medicine. Oxford: Health Press, 152p.
Authored Book - Other
Pollard, A. J., & Murdoch, D. R. (1998). The High Altitude Medicine Handbook (2 ed.). Abingdon: Radcliffe Medical Press, 165p.
Authored Book - Other
Pollard, A. J., Litch, J. A., & Murdoch, D. R. (1998). Children at altitude. In H. Ohno, T. Kobayashi, S. Masuyama & M. Nakashima (Eds.), Progress in mountain medicine and high mountain physiology. (pp. 422-424). Japanese Society of Mountain Medicine.
Chapter in Book - Research
