BSc(Hons), MBChB, MD, FRACP
Current Role
Clinical Director, New Zealand Brain Research Institute
Publications
Zhao, Y., Laansma, M. A., van Heese, E. M., Owens-Walton, C., Parkes, L. M., Debove, I., … Anderson, T. J., … Melzer, T. R., Pitcher, T. L., … and for the ENIGMA consortium. (2022). Learning interpretable regularized ordinal models from 3D mesh data for neurodegenerative disease staging. In A. Abdulkadir, D. R. Bathula, N. C. Dvornek, M. Habes, S. Mostafa Kia, V. Kumar & T. Wolfers (Eds.), Machine Learning in Clinical Neuroimaging: Proceedings of the 5th International Workshop, held in conjunction with the 25th International Conference on Medical Imaging Computing and Computer Assisted Intervention (MICCAI): Lecture notes in computer science (Vol. 13596). (pp. 115-124). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-17899-3_12
Le Heron, C., MacAskill, M., Horne, K.-L., Livingston, L., Melzer, T., Myall, D., Pitcher, T., Dalrymple-Alford, J., Anderson, T., & Harrison, S. (2022). Temporal dynamics and longitudinal predictors of apathy in Parkinson's disease. Movement Disorders, 37(Suppl. 2), (pp. S630). doi: 10.1002/mds.29223
Slater, N., Shoorangiz, R., Hall-McMaster, G., Harris, A., Livingston, L., Grenfell, S., … Anderson, T., Melzer, T., & Dalrymple-Alford, J. (2022). Parkinson's disease and nucleus basalis of Meynert integrity: Cognition and everyday function. Movement Disorders, 37(Suppl. 2), (pp. S95). doi: 10.1002/mds.29223
Shoorangiz, R., Slater, N., Hall-McMaster, G., Peterson, E., Livingston, L., Grenfell, S., … Jones, R., Anderson, T., Melzer, T., & Dalrymple-Alford, J. (2022). EEG power-spectra parametrization and cognitive ability in Parkinson's disease. Movement Disorders, 37(Suppl. 2), (pp. S94-S95). doi: 10.1002/mds.29223
Nolan, D., Myall, D., Morgan, C., Shoorangiz, R., Livingston, L., Grenfell, S., Pitcher, T., MacAskill, M., Horne, K.-L., Le Heron, C., … Dalrymple-Alford, J., Anderson, T., & Melzer, T. (2022). MRI to investigate cerebrovascular changes in Parkinson's disease. Movement Disorders, 37(Suppl. 2), (pp. S87). doi: 10.1002/mds.29223
Bloomer, J., Pitcher, T., Mustapic, M., Eren, E., Yao, P. J., Vreones, M. P., … Dalrymple-Alford, J., Shoorangiz, R., Meissner, W. G., Anderson, T., & Kapogiannis, D. (2022). Extracellular vesicle biomarkers for cognitive impairment in Parkinson's disease. Brain. Advance online publication. doi: 10.1093/brain/awac258
Journal - Research Article
Khwaounjoo, P., Singh, G., Grenfell, S., Özsoy, B., MacAskill, M. R., Anderson, T. J., & Çakmak, Y. O. (2022). Non-contact hand movement analysis for optimal configuration of smart sensors to capture Parkinson's disease hand tremor. Sensors, 22(12), 4613. doi: 10.3390/s22124613
Journal - Research Article
MacAskill, M. R., Pitcher, T. L., Melzer, T. R., Myall, D. J., Horne, K.-L., Shoorangiz, R., … Livingston, L., … Pascoe, M. J., Marshall, E. T., … Perry, S. E., Meissner, W. G., … Le Heron, C. J., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2022). The New Zealand Parkinson’s progression programme. Journal of the Royal Society of New Zealand. Advance online publication. doi: 10.1080/03036758.2022.2111448
Journal - Research Article
Morgan, C. A., Roberts, R. P., Chaffey, T., Tahara-Eckl, L., van der Meer, M., Günther, M., Anderson, T. J., … Dalrymple-Alford, J. C., … Melzer, T. R. (2022). Reproducibility and repeatability of magnetic resonance imaging in dementia. Physica Medica, 101, 8-17. doi: 10.1016/j.ejmp.2022.06.012
Journal - Research Article
Tippett, L. J., Cawston, E. E., Morgan, C. A., Melzer, T. R., Brickell, K. L., Ilse, C., … Le Heron, C., Buchanan, S., … Anderson, T. J., Williams, J. M., Cutfield, N. J., Dalrymple-Alford, J. C., … the NZ-DPRC. (2022). Dementia Prevention Research Clinic: A longitudinal study investigating factors influencing the development of Alzheimer’s disease in Aotearoa, New Zealand. Journal of the Royal Society of New Zealand. Advance online publication. doi: 10.1080/03036758.2022.2098780
Journal - Research Article
Basukala, D., Mukundan, R., Lim, A., Hurrell, M. A., Keenan, R. J., Dalrymple-Alford, J. C., Anderson, T. J., Myall, D. J., & Melzer, T. R. (2021). Automated segmentation of substantia nigra and red nucleus using quantitative susceptibility mapping images: Application to Parkinson's disease. Computers & Electrical Engineering, 91, 107091. doi: 10.1016/j.compeleceng.2021.107091
Journal - Research Article
Blakemore, R. L., Pascoe, M. J., Horne, K.-L., Livingston, L., Young, B. N., Elias, B., … Pitcher, T. L., Dalrymple-Alford, J. C., Le Heron, C. J., Anderson, T. J., & MacAskill, M. R. (2021). Higher perceived stress and exacerbated motor symptoms in Parkinson's disease during the COVID-19 lockdown in New Zealand. New Zealand Medical Journal, 134(1538), 44-51. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Article
Horne, K.-L., MacAskill, M. R., Myall, D. J., Livingston, L., Grenfell, S., Pascoe, M. J., … Shoorangiz, R., Melzer, T. R., Pitcher, T. L., Anderson, T. J., & Dalrymple-Alford, J. C. (2021). Neuropsychiatric symptoms are associated with dementia in Parkinson's disease but not predictive of it. Movement Disorders Clinical Practice, 8(3), 390-399. doi: 10.1002/mdc3.13151
Journal - Research Article
Laansma, M. A., Bright, J. K., Al-Bachari, S., Anderson, T. J., Ard, T., Assogna, F., … Dalrymple-Alford, J., … Melzer, T. R., … Pitcher, T. L., … and the ENIGMA-Parkinson's Study. (2021). International multicenter analysis of brain structure across clinical stages of Parkinson's disease. Movement Disorders, 36(11), 2583-2594. doi: 10.1002/mds.28706
Journal - Research Article
Le Heron, C., MacAskill, M., Mason, D., Dalrymple-Alford, J., Anderson, T., Pitcher, T., & Myall, D. (2021). A multi-step model of Parkinson's disease pathogenesis. Movement Disorders, 36(1), 2530-2538. doi: 10.1002/mds.28719
Journal - Research Article
Morgan, C. A., Melzer, T. R., Roberts, R. P., Wiebels, K., Mutsaerts, H. J. M. M., Spriggs, M. J., … Anderson, T. J., Cutfield, N. J., … Tippett, L. J. (2021). Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia. Scientific Reports, 11, 23325. doi: 10.1038/s41598-021-02313-z
Journal - Research Article
Nabais, M. F., Laws, S. M., Lin, T., Vallerga, C. L., Armstrong, N. J., Blair, I. P., … Anderson, T. J., … Kennedy, M., … Pearson, J., Pitcher, T. L., … McRae, A. F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22(1), 90. doi: 10.1186/s13059-021-02275-5
Journal - Research Article
Alamri, Y., Dalrymple-Alford, J., MacAskill, M., & Anderson, T. J. (2020). Exploring eye movements of Parkinson's disease patients performing the Judgement of line orientation test. Journal of Clinical Neuroscience, 76, 183-188. doi: 10.1016/j.jocn.2020.04.031
Journal - Research Article
Fan, D., Pitcher, T., Dalrymple-Alford, J., MacAskill, M., Anderson, T., & Guan, J. (2020). Changes of plasma cGP/IGF-1 molar ratio with age is associated with cognitive status of Parkinson disease. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 12(1), e12025. doi: 10.1002/dad2.12025
Journal - Research Article
Graham, O. E. E., Pitcher, T. L., Liau, Y., Miller, A. L., Dalrymple-Alford, J. C., Anderson, T. J., & Kennedy, M. A. (2020). Nanopore sequencing of the glucocerebrosidase (GBA) gene in a New Zealand Parkinson's disease cohort. Parkinsonism & Related Disorders, 70, 36-41. doi: 10.1016/j.parkreldis.2019.11.022
Journal - Research Article
Hofer, E., Roshchupkin, G. V., Adams, H. H. H., Knol, M. J., Lin, H., Li, S., … ENIGMA consortium, including Pitcher, T. L., Melzer, T. R., Anderson, T. J., … Seshadri, S. (2020). Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications, 11, 4796. doi: 10.1038/s41467-020-18367-y
Journal - Research Article
MacAskill, M. R., Myall, D. J., Shoorangiz, R., Anderson, T. J., & Pitcher, T. L. (2020). Childbirth and delayed parkinson's onset: A reproducible nonbiological artifact of societal change. Movement Disorders, 35(7), 1268-1271. doi: 10.1002/mds.28135
Journal - Research Article
Schierding, W., Farrow, S., Fadason, T., Graham, O. E. E., Pitcher, T. L., Qubisi, S., … Anderson, T. J., Kennedy, M. A., … O'Sullivan, J. M. (2020). Common variants coregulate expression of GBA and modifier genes to delay Parkinson's disease onset. Movement Disorders, 35(8), 1346-1356. doi: 10.1002/mds.28144
Journal - Research Article
Snell, D. L., Martin, R., Surgenor, L. J., Siegert, R. J., Hay-Smith, E. J. C., Melzer, T. R., Anderson, T. J., & Hooper, G. J. (2020). Wrestling with uncertainty after mild traumatic brain injury: A mixed methods study. Disability & Rehabilitation, 42(14), 1942-1953. doi: 10.1080/09638288.2018.1542461
Journal - Research Article
Spencer, E. S., Pitcher, T., Veron, G., Hannam, T., MacAskill, M., Anderson, T., Dalrymple-Alford, J., & Carr, A. C. (2020). Positive association of ascorbate and inverse association of urate with cognitive function in people with Parkinson’s disease. Antioxidants, 9(10), 1-13. doi: 10.3390/antiox9100906
Journal - Research Article
Blakemore, R. L., MacAskill, M. R., Myall, D. J., & Anderson, T. J. (2019). Volitional suppression of parkinsonian resting tremor. Movement Disorders Clinical Practice, 6(6), 470-478. doi: 10.1002/mdc3.12801
Journal - Research Article
d'Arbeloff, T., Elliott, M. L., Knodt, A. R., Melzer, T. R., Keenan, R., Ireland, D., Ramrakha, S., Poulton, R., Anderson, T., … Hariri, A. R. (2019). White matter hyperintensities are common in midlife and already associated with cognitive decline. Brain Communications, 1(1), fcz041. doi: 10.1093/braincomms/fcz041
Journal - Research Article
Melzer, T. R., Stark, M. R., Keenan, R. J., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Grenfell, S., Horne, K.-L., … Pascoe, M., Almuqbel, M. M., … Miller, D. H., Dalrymple-Alford, J. C., & Anderson, T. J. (2019). Beta amyloid deposition is not associated with cognitive impairment in Parkinson’s Disease. Frontiers in Neurology, 10, 391. doi: 10.3389/fneur.2019.00391
Journal - Research Article
Reynolds, R. H., Botía, J., Nalls, M. A., International Parkinson's Disease Genomics Consortium (IPDGC), including System Genomics of Parkinson's Disease (SGPD), Anderson, T., … Kennedy, M., Pearson, J., … Ryten, M. (2019). Moving beyond neurons: The role of cell type-specific gene regulation in Parkinson's disease heritability. npj Parkinson's Disease, 5, 6. doi: 10.1038/s41531-019-0076-6
Journal - Research Article
Watanabe, M., Okada, K.-I., Hamasaki, Y., Funamoto, M., Kobayashi, Y., MacAskill, M., & Anderson, T. (2019). Ocular drift reflects volitional action preparation. European Journal of Neuroscience, 50, 1892-1910. doi: 10.1111/ejn.14365
Journal - Research Article
Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., … Kennedy, M., Pitcher, T., Pearson, J., … Anderson, T., … Visscher, P. M. (2019). Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Medicine, 11(1), 54. doi: 10.1186/s13073-019-0667-1
Journal - Research Article
Blakemore, R. L., MacAskill, M. R., Shoorangiz, R., & Anderson, T. J. (2018). Stress-evoking emotional stimuli exaggerate deficits in motor function in Parkinson's disease. Neuropsychologia, 112, 66-76. doi: 10.1016/j.neuropsychologia.2018.03.006
Journal - Research Article
Fan, D., Alamri, Y., Liu, K., MacAskill, M., Harris, P., Brimble, M., … Anderson, T., & Guan, J. (2018). Supplementation of blackcurrant anthocyanins increased cyclic glycine-proline in the cerebrospinal fluid of Parkinson patients: Potential treatment to improve insulin-like growth factor-1 function. Nutrients, 10(6), 714. doi: 10.3390/nu10060714
Journal - Research Article
Pitcher, T. L., Myall, D. J., Pearson, J. F., Lacey, C. J., Dalrymple-Alford, J. C., Anderson, T. J., & MacAskill, M. R. (2018). Parkinson's disease across ethnicities: A nationwide study in New Zealand. Movement Disorders, 33(9), 1440-1448. doi: 10.1002/mds.27389
Journal - Research Article
Snell, D. L., Martin, R., Macleod, A. D., Surgenor, L. J., Siegert, R. J., Hay-Smith, E. J. C., Melzer, T., Hooper, G. J., & Anderson, T. (2018). Untangling chronic pain and post-concussion symptoms: The significance of depression. Brain Injury, 32(5), 583-592. doi: 10.1080/02699052.2018.1432894
Journal - Research Article
Wu, L., Liu, F.-T., Ge, J.-J., Zhao, J., Tang, Y.-L., Yu, W.-B., … Anderson, T., … Wang, J. (2018). Clinical characteristics of cognitive impairment in patients with Parkinson's disease and its related pattern in 18F-FDG PET imaging. Human Brain Mapping, 39(12), 2652-2662. doi: 10.1002/hbm.24311
Journal - Research Article
Al-Busaidi, I. S., Anderson, T. J., & Alamri, Y. (2017). Qualitative analysis of Parkinson’s disease information on social media: The case of YouTube™. EPMA Journal, 8(3), 273-277. doi: 10.1007/s13167-017-0113-7
Journal - Research Article
Jones, A. J., Kuijer, R. G., Livingston, L., Myall, D., Horne, K., MacAskill, M., Pitcher, T., … Anderson, T. J., & Dalrymple-Alford, J. C. (2017). Caregiver burden is increased in Parkinson's disease with mild cognitive impairment (PD-MCI). Translational Neurodegeneration, 6, 17. doi: 10.1186/s40035-017-0085-5
Journal - Research Article
Macleod, A. D., Jury, M. A., & Anderson, T. (2017). The (palliative) care of Huntington’s disease. Progress in Palliative Care, 25(4), 165-170. doi: 10.1080/09699260.2017.1337608
Journal - Research Article
Myall, D. J., Pitcher, T. L., Pearson, J. F., Dalrymple-Alford, J. C., Anderson, T. J., & MacAskill, M. R. (2017). Parkinson's in the oldest old: Impact on estimates of future disease burden. Parkinsonism & Related Disorders, 42, 78-84. doi: 10.1016/j.parkreldis.2017.06.018
Journal - Research Article
Pearson, J. F., Alla, S., Clarke, G., Mason, D. F., Anderson, T., Richardson, A., Miller, D. H., … Abernethy, D. A., … Taylor, B. V. (2017). Multiple sclerosis impact on employment and income in New Zealand. Acta Neurologica Scandinavica, 136(3), 223-232. doi: 10.1111/ane.12714
Journal - Research Article
Woodward, Z., Prickett, T. C. R., Espiner, E. A., & Anderson, T. J. (2017). Central and systemic C-type Natriuretic Peptide are both reduced in Parkinson's Disease. Parkinsonism & Related Disorders, 43, 15-19. doi: 10.1016/j.parkreldis.2017.06.019
Journal - Research Article
Almuqbel, M., Melzer, T. R., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Wood, K.-L., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson’s disease in a clinical setting. Parkinsonism & Related Disorders, 22, 54-61. doi: 10.1016/j.parkreldis.2015.11.008
Journal - Research Article
MacAskill, M. R., & Anderson, T. J. (2016). Eye movements in neurodegenerative diseases. Current Opinion in Neurology, 29(1), 61-68. doi: 10.1097/wco.0000000000000274
Journal - Research Article
Mace, J. L., Porter, R. J., Dalrymple-Alford, J. C., Collins, C., & Anderson, T. J. (2016). Acute tryptophan depletion and Lewy body dementias. International Psychogeriatrics, 28(9), 1487-1491. doi: 10.1017/s1041610216000284
Journal - Research Article
Schluter, P. J., Ahuriri-Driscoll, A., Anderson, T. J., Beere, P., Brown, J., Dalrymple-Alford, J., … Gillon, D. A., … Keeling, S., … Lacey, C., … Millar, N., Mor, V., & Jamieson, H. A. (2016). Comprehensive clinical assessment of home-based older persons within New Zealand: An epidemiological profile of a national cross-section. Australian & New Zealand Journal of Public Health, 40(4), 349-355. doi: 10.1111/1753-6405.12525
Journal - Research Article
Snell, D. L., MacLeod, S. A. D., & Anderson, T. (2016). Post-concussion syndrome after a mild traumatic brain injury: A minefield for clinical practice. Journal of Behavioral & Brain Science, 6(6), 227-232. doi: 10.4236/jbbs.2016.66023
Journal - Research Article
Wood, K.-L., Myall, D. J., Livingston, L., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., … Anderson, T. J., & Dalrymple-Alford, J. C. (2016). Different PD-MCI criteria and risk of dementia in Parkinson's disease: A 4-year longitudinal study. npj Parkinson's Disease, 2, 15027. doi: 10.1038/npjparkd.2015.27
Journal - Research Article
Alamri, Y., MacAskill, M., Anderson, T., & Benamer, H. (2015). Parkinson's disease in the Gulf countries: An updated review. European Neurology, 74(3-4), 222-225. doi: 10.1159/000442283
Journal - Research Article
Luckey, A. M., Anderson, T., Silverman, M. H., & Webster, G. (2015). Safety, tolerability and pharmacodynamics of a novel immunomodulator, MIS416, in patients with chronic progressive multiple sclerosis. Multiple Sclerosis Journal: Experimental Translational Clinical. doi: 10.1177/2055217315583385
Journal - Research Article
Martin, T., Weatherall, M., Anderson, T. J., & MacAskill, M. R. (2015). A randomized controlled feasibility trial of a specific cueing program for falls management in persons with Parkinson disease and freezing of gait. Journal of Neurologic Physical Therapy, 39, 179-184. doi: 10.1097/npt.0000000000000093
Journal - Research Article
Melzer, T. R., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Watts, R., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2015). Tracking Parkinson's disease over one year with multimodal magnetic resonance imaging in a group of older patients with moderate disease. PLoS ONE, 10(12), e0143923. doi: 10.1371/journal.pone.0143923
Journal - Research Article
Wilcox, R., Brænne, I., Brüggemann, N., Winkler, S., Wiegers, K., Bertram, L., Anderson, T., & Lohmann, K. (2015). Genome sequencing identifies a novel mutation in ATP1A3 in a family with dystonia in females only. Journal of Neurology, 262(1), 187-193. doi: 10.1007/s00415-014-7547-9
Journal - Research Article
Baylor, C., McAuliffe, M. J., Hughes, L. E., Yorkston, K., Anderson, T., Kim, J., & Amtmann, D. (2014). A Differential Item Functioning (DIF) analysis of the Communicative Participation Item Bank (CPIB): Comparing individuals with Parkinson's disease from the United States and New Zealand. Journal of Speech, Language & Hearing Research, 57, 90-95. doi: 10.1044/1092-4388(2013/12-0414)
Journal - Research Article
Espiner, E. A., Dalrymple-Alford, J. C., Prickett, T. C. R., Alamri, Y., & Anderson, T. J. (2014). C-type natriuretic peptide in Parkinson's disease: Reduced secretion and response to deprenyl. Journal of Neural Transmission, 121(4), 371-378. doi: 10.1007/s00702-013-1123-9
Journal - Research Article