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Professor Tim Anderson

Tim AndersonBSc(Hons), MBChB, MD, FRACP

Current Role

Clinical Director, New Zealand Brain Research Institute

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Publications

Gooch, E. A., Horne, K.-L., Melzer, T. R., McAuliffe, M. J., MacAskill, M., Dalrymple-Alford, J. C., Anderson, T. J., & Theys, C. (2023). Acquired stuttering in Parkinson's disease. Movement Disorders Clinical Practice, 13758. Advance online publication. doi: 10.1002/mdc3.13758

Morris, L.-A., Harrison, S. J., Melzer, T. R., Dalrymple-Alford, J. C., Anderson, T. J., MacAskill, M. R., & Le Heron, C. J. (2023). Altered nucleus accumbens functional connectivity precedes apathy in Parkinson's disease. Brain. Advance online publication. doi: 10.1093/brain/awad113

Guan, J., Li, F., Kang, D., Anderson, T., Pitcher, T., Dalrymple-Alford, J., … Singh-Mallah, G. (2023). Cyclic glycine-proline (cGP) normalises insulin-like growth factor-1 (IGF-1) function: Significance in the ageing brain and in age-related neurological conditions. Molecules, 28, 1021. doi: 10.3390/molecules28031021

Bloomer, J., Pitcher, T., Mustapic, M., Eren, E., Yao, P. J., Vreones, M. P., … Dalrymple-Alford, J., Shoorangiz, R., Meissner, W. G., Anderson, T., & Kapogiannis, D. (2023). Extracellular vesicle biomarkers for cognitive impairment in Parkinson's disease. Brain, 146, 195-208. doi: 10.1093/brain/awac258

Zhao, Y., van Heese, E., Laansma, M. A., Al-Bachari, S., Anderson, T., Assogna, F., … Dalrymple-Alford, J., … Melzer, T. R., … Pitcher, T., … Gutman, B. A. (2022). TV-L1 ordinal logistic regression reveals new morphometric patterns related to Parkinsonian symptom severity: An ENIGMA-PD study. Alzheimer's & Dementia, 18(Suppl. 6), e067037. doi: 10.1002/alz.067037

Bloomer, J., Pitcher, T., Mustapic, M., Eren, E., Yao, P. J., Vreones, M. P., … Dalrymple-Alford, J., Shoorangiz, R., Meissner, W. G., Anderson, T., & Kapogiannis, D. (2023). Extracellular vesicle biomarkers for cognitive impairment in Parkinson's disease. Brain, 146, 195-208. doi: 10.1093/brain/awac258

Journal - Research Article

Gooch, E. A., Horne, K.-L., Melzer, T. R., McAuliffe, M. J., MacAskill, M., Dalrymple-Alford, J. C., Anderson, T. J., & Theys, C. (2023). Acquired stuttering in Parkinson's disease. Movement Disorders Clinical Practice, 13758. Advance online publication. doi: 10.1002/mdc3.13758

Journal - Research Article

Morris, L.-A., Harrison, S. J., Melzer, T. R., Dalrymple-Alford, J. C., Anderson, T. J., MacAskill, M. R., & Le Heron, C. J. (2023). Altered nucleus accumbens functional connectivity precedes apathy in Parkinson's disease. Brain. Advance online publication. doi: 10.1093/brain/awad113

Journal - Research Article

Khwaounjoo, P., Singh, G., Grenfell, S., Özsoy, B., MacAskill, M. R., Anderson, T. J., & Çakmak, Y. O. (2022). Non-contact hand movement analysis for optimal configuration of smart sensors to capture Parkinson's disease hand tremor. Sensors, 22(12), 4613. doi: 10.3390/s22124613

Journal - Research Article

MacAskill, M. R., Pitcher, T. L., Melzer, T. R., Myall, D. J., Horne, K.-L., Shoorangiz, R., … Livingston, L., … Pascoe, M. J., Marshall, E. T., … Perry, S. E., Meissner, W. G., … Le Heron, C. J., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2022). The New Zealand Parkinson’s progression programme. Journal of the Royal Society of New Zealand. Advance online publication. doi: 10.1080/03036758.2022.2111448

Journal - Research Article

Morgan, C. A., Roberts, R. P., Chaffey, T., Tahara-Eckl, L., van der Meer, M., Günther, M., Anderson, T. J., … Dalrymple-Alford, J. C., … Melzer, T. R. (2022). Reproducibility and repeatability of magnetic resonance imaging in dementia. Physica Medica, 101, 8-17. doi: 10.1016/j.ejmp.2022.06.012

Journal - Research Article

Tippett, L. J., Cawston, E. E., Morgan, C. A., Melzer, T. R., Brickell, K. L., Ilse, C., … Le Heron, C., Buchanan, S., … Anderson, T. J., Williams, J. M., Cutfield, N. J., Dalrymple-Alford, J. C., … the NZ-DPRC. (2022). Dementia Prevention Research Clinic: A longitudinal study investigating factors influencing the development of Alzheimer’s disease in Aotearoa, New Zealand. Journal of the Royal Society of New Zealand. Advance online publication. doi: 10.1080/03036758.2022.2098780

Journal - Research Article

Zhao, Y., van Heese, E., Laansma, M. A., Al-Bachari, S., Anderson, T., Assogna, F., … Dalrymple-Alford, J., … Melzer, T. R., … Pitcher, T., … Gutman, B. A. (2022). TV-L1 ordinal logistic regression reveals new morphometric patterns related to Parkinsonian symptom severity: An ENIGMA-PD study. Alzheimer's & Dementia, 18(Suppl. 6), e067037. doi: 10.1002/alz.067037

Journal - Research Article

Basukala, D., Mukundan, R., Lim, A., Hurrell, M. A., Keenan, R. J., Dalrymple-Alford, J. C., Anderson, T. J., Myall, D. J., & Melzer, T. R. (2021). Automated segmentation of substantia nigra and red nucleus using quantitative susceptibility mapping images: Application to Parkinson's disease. Computers & Electrical Engineering, 91, 107091. doi: 10.1016/j.compeleceng.2021.107091

Journal - Research Article

Blakemore, R. L., Pascoe, M. J., Horne, K.-L., Livingston, L., Young, B. N., Elias, B., … Pitcher, T. L., Dalrymple-Alford, J. C., Le Heron, C. J., Anderson, T. J., & MacAskill, M. R. (2021). Higher perceived stress and exacerbated motor symptoms in Parkinson's disease during the COVID-19 lockdown in New Zealand. New Zealand Medical Journal, 134(1538), 44-51. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Horne, K.-L., MacAskill, M. R., Myall, D. J., Livingston, L., Grenfell, S., Pascoe, M. J., … Shoorangiz, R., Melzer, T. R., Pitcher, T. L., Anderson, T. J., & Dalrymple-Alford, J. C. (2021). Neuropsychiatric symptoms are associated with dementia in Parkinson's disease but not predictive of it. Movement Disorders Clinical Practice, 8(3), 390-399. doi: 10.1002/mdc3.13151

Journal - Research Article

Laansma, M. A., Bright, J. K., Al-Bachari, S., Anderson, T. J., Ard, T., Assogna, F., … Dalrymple-Alford, J., … Melzer, T. R., … Pitcher, T. L., … and the ENIGMA-Parkinson's Study. (2021). International multicenter analysis of brain structure across clinical stages of Parkinson's disease. Movement Disorders, 36(11), 2583-2594. doi: 10.1002/mds.28706

Journal - Research Article

Le Heron, C., MacAskill, M., Mason, D., Dalrymple-Alford, J., Anderson, T., Pitcher, T., & Myall, D. (2021). A multi-step model of Parkinson's disease pathogenesis. Movement Disorders, 36(1), 2530-2538. doi: 10.1002/mds.28719

Journal - Research Article

Morgan, C. A., Melzer, T. R., Roberts, R. P., Wiebels, K., Mutsaerts, H. J. M. M., Spriggs, M. J., … Anderson, T. J., Cutfield, N. J., … Tippett, L. J. (2021). Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia. Scientific Reports, 11, 23325. doi: 10.1038/s41598-021-02313-z

Journal - Research Article

Nabais, M. F., Laws, S. M., Lin, T., Vallerga, C. L., Armstrong, N. J., Blair, I. P., … Anderson, T. J., … Kennedy, M., … Pearson, J., Pitcher, T. L., … McRae, A. F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22(1), 90. doi: 10.1186/s13059-021-02275-5

Journal - Research Article

Alamri, Y., Dalrymple-Alford, J., MacAskill, M., & Anderson, T. J. (2020). Exploring eye movements of Parkinson's disease patients performing the Judgement of line orientation test. Journal of Clinical Neuroscience, 76, 183-188. doi: 10.1016/j.jocn.2020.04.031

Journal - Research Article

Fan, D., Pitcher, T., Dalrymple-Alford, J., MacAskill, M., Anderson, T., & Guan, J. (2020). Changes of plasma cGP/IGF-1 molar ratio with age is associated with cognitive status of Parkinson disease. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 12(1), e12025. doi: 10.1002/dad2.12025

Journal - Research Article

Graham, O. E. E., Pitcher, T. L., Liau, Y., Miller, A. L., Dalrymple-Alford, J. C., Anderson, T. J., & Kennedy, M. A. (2020). Nanopore sequencing of the glucocerebrosidase (GBA) gene in a New Zealand Parkinson's disease cohort. Parkinsonism & Related Disorders, 70, 36-41. doi: 10.1016/j.parkreldis.2019.11.022

Journal - Research Article

Hofer, E., Roshchupkin, G. V., Adams, H. H. H., Knol, M. J., Lin, H., Li, S., … ENIGMA consortium, including Pitcher, T. L., Melzer, T. R., Anderson, T. J., … Seshadri, S. (2020). Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications, 11, 4796. doi: 10.1038/s41467-020-18367-y

Journal - Research Article

MacAskill, M. R., Myall, D. J., Shoorangiz, R., Anderson, T. J., & Pitcher, T. L. (2020). Childbirth and delayed parkinson's onset: A reproducible nonbiological artifact of societal change. Movement Disorders, 35(7), 1268-1271. doi: 10.1002/mds.28135

Journal - Research Article

Schierding, W., Farrow, S., Fadason, T., Graham, O. E. E., Pitcher, T. L., Qubisi, S., … Anderson, T. J., Kennedy, M. A., … O'Sullivan, J. M. (2020). Common variants coregulate expression of GBA and modifier genes to delay Parkinson's disease onset. Movement Disorders, 35(8), 1346-1356. doi: 10.1002/mds.28144

Journal - Research Article

Snell, D. L., Martin, R., Surgenor, L. J., Siegert, R. J., Hay-Smith, E. J. C., Melzer, T. R., Anderson, T. J., & Hooper, G. J. (2020). Wrestling with uncertainty after mild traumatic brain injury: A mixed methods study. Disability & Rehabilitation, 42(14), 1942-1953. doi: 10.1080/09638288.2018.1542461

Journal - Research Article

Spencer, E. S., Pitcher, T., Veron, G., Hannam, T., MacAskill, M., Anderson, T., Dalrymple-Alford, J., & Carr, A. C. (2020). Positive association of ascorbate and inverse association of urate with cognitive function in people with Parkinson’s disease. Antioxidants, 9(10), 1-13. doi: 10.3390/antiox9100906

Journal - Research Article

Blakemore, R. L., MacAskill, M. R., Myall, D. J., & Anderson, T. J. (2019). Volitional suppression of parkinsonian resting tremor. Movement Disorders Clinical Practice, 6(6), 470-478. doi: 10.1002/mdc3.12801

Journal - Research Article

d'Arbeloff, T., Elliott, M. L., Knodt, A. R., Melzer, T. R., Keenan, R., Ireland, D., Ramrakha, S., Poulton, R., Anderson, T., … Hariri, A. R. (2019). White matter hyperintensities are common in midlife and already associated with cognitive decline. Brain Communications, 1(1), fcz041. doi: 10.1093/braincomms/fcz041

Journal - Research Article

Melzer, T. R., Stark, M. R., Keenan, R. J., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Grenfell, S., Horne, K.-L., … Pascoe, M., Almuqbel, M. M., … Miller, D. H., Dalrymple-Alford, J. C., & Anderson, T. J. (2019). Beta amyloid deposition is not associated with cognitive impairment in Parkinson’s Disease. Frontiers in Neurology, 10, 391. doi: 10.3389/fneur.2019.00391

Journal - Research Article

Reynolds, R. H., Botía, J., Nalls, M. A., International Parkinson's Disease Genomics Consortium (IPDGC), including System Genomics of Parkinson's Disease (SGPD), Anderson, T., … Kennedy, M., Pearson, J., … Ryten, M. (2019). Moving beyond neurons: The role of cell type-specific gene regulation in Parkinson's disease heritability. npj Parkinson's Disease, 5, 6. doi: 10.1038/s41531-019-0076-6

Journal - Research Article

Watanabe, M., Okada, K.-I., Hamasaki, Y., Funamoto, M., Kobayashi, Y., MacAskill, M., & Anderson, T. (2019). Ocular drift reflects volitional action preparation. European Journal of Neuroscience, 50, 1892-1910. doi: 10.1111/ejn.14365

Journal - Research Article

Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., … Kennedy, M., Pitcher, T., Pearson, J., … Anderson, T., … Visscher, P. M. (2019). Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Medicine, 11(1), 54. doi: 10.1186/s13073-019-0667-1

Journal - Research Article

Blakemore, R. L., MacAskill, M. R., Shoorangiz, R., & Anderson, T. J. (2018). Stress-evoking emotional stimuli exaggerate deficits in motor function in Parkinson's disease. Neuropsychologia, 112, 66-76. doi: 10.1016/j.neuropsychologia.2018.03.006

Journal - Research Article

Fan, D., Alamri, Y., Liu, K., MacAskill, M., Harris, P., Brimble, M., … Anderson, T., & Guan, J. (2018). Supplementation of blackcurrant anthocyanins increased cyclic glycine-proline in the cerebrospinal fluid of Parkinson patients: Potential treatment to improve insulin-like growth factor-1 function. Nutrients, 10(6), 714. doi: 10.3390/nu10060714

Journal - Research Article

Pitcher, T. L., Myall, D. J., Pearson, J. F., Lacey, C. J., Dalrymple-Alford, J. C., Anderson, T. J., & MacAskill, M. R. (2018). Parkinson's disease across ethnicities: A nationwide study in New Zealand. Movement Disorders, 33(9), 1440-1448. doi: 10.1002/mds.27389

Journal - Research Article

Snell, D. L., Martin, R., Macleod, A. D., Surgenor, L. J., Siegert, R. J., Hay-Smith, E. J. C., Melzer, T., Hooper, G. J., & Anderson, T. (2018). Untangling chronic pain and post-concussion symptoms: The significance of depression. Brain Injury, 32(5), 583-592. doi: 10.1080/02699052.2018.1432894

Journal - Research Article

Wu, L., Liu, F.-T., Ge, J.-J., Zhao, J., Tang, Y.-L., Yu, W.-B., … Anderson, T., … Wang, J. (2018). Clinical characteristics of cognitive impairment in patients with Parkinson's disease and its related pattern in 18F-FDG PET imaging. Human Brain Mapping, 39(12), 2652-2662. doi: 10.1002/hbm.24311

Journal - Research Article

Al-Busaidi, I. S., Anderson, T. J., & Alamri, Y. (2017). Qualitative analysis of Parkinson’s disease information on social media: The case of YouTube™. EPMA Journal, 8(3), 273-277. doi: 10.1007/s13167-017-0113-7

Journal - Research Article

Jones, A. J., Kuijer, R. G., Livingston, L., Myall, D., Horne, K., MacAskill, M., Pitcher, T., … Anderson, T. J., & Dalrymple-Alford, J. C. (2017). Caregiver burden is increased in Parkinson's disease with mild cognitive impairment (PD-MCI). Translational Neurodegeneration, 6, 17. doi: 10.1186/s40035-017-0085-5

Journal - Research Article

Macleod, A. D., Jury, M. A., & Anderson, T. (2017). The (palliative) care of Huntington’s disease. Progress in Palliative Care, 25(4), 165-170. doi: 10.1080/09699260.2017.1337608

Journal - Research Article

Myall, D. J., Pitcher, T. L., Pearson, J. F., Dalrymple-Alford, J. C., Anderson, T. J., & MacAskill, M. R. (2017). Parkinson's in the oldest old: Impact on estimates of future disease burden. Parkinsonism & Related Disorders, 42, 78-84. doi: 10.1016/j.parkreldis.2017.06.018

Journal - Research Article

Pearson, J. F., Alla, S., Clarke, G., Mason, D. F., Anderson, T., Richardson, A., Miller, D. H., … Abernethy, D. A., … Taylor, B. V. (2017). Multiple sclerosis impact on employment and income in New Zealand. Acta Neurologica Scandinavica, 136(3), 223-232. doi: 10.1111/ane.12714

Journal - Research Article

Woodward, Z., Prickett, T. C. R., Espiner, E. A., & Anderson, T. J. (2017). Central and systemic C-type Natriuretic Peptide are both reduced in Parkinson's Disease. Parkinsonism & Related Disorders, 43, 15-19. doi: 10.1016/j.parkreldis.2017.06.019

Journal - Research Article

Almuqbel, M., Melzer, T. R., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Wood, K.-L., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson’s disease in a clinical setting. Parkinsonism & Related Disorders, 22, 54-61. doi: 10.1016/j.parkreldis.2015.11.008

Journal - Research Article

MacAskill, M. R., & Anderson, T. J. (2016). Eye movements in neurodegenerative diseases. Current Opinion in Neurology, 29(1), 61-68. doi: 10.1097/wco.0000000000000274

Journal - Research Article

Mace, J. L., Porter, R. J., Dalrymple-Alford, J. C., Collins, C., & Anderson, T. J. (2016). Acute tryptophan depletion and Lewy body dementias. International Psychogeriatrics, 28(9), 1487-1491. doi: 10.1017/s1041610216000284

Journal - Research Article

Schluter, P. J., Ahuriri-Driscoll, A., Anderson, T. J., Beere, P., Brown, J., Dalrymple-Alford, J., … Gillon, D. A., … Keeling, S., … Lacey, C., … Millar, N., Mor, V., & Jamieson, H. A. (2016). Comprehensive clinical assessment of home-based older persons within New Zealand: An epidemiological profile of a national cross-section. Australian & New Zealand Journal of Public Health, 40(4), 349-355. doi: 10.1111/1753-6405.12525

Journal - Research Article

Snell, D. L., MacLeod, S. A. D., & Anderson, T. (2016). Post-concussion syndrome after a mild traumatic brain injury: A minefield for clinical practice. Journal of Behavioral & Brain Science, 6(6), 227-232. doi: 10.4236/jbbs.2016.66023

Journal - Research Article

Wood, K.-L., Myall, D. J., Livingston, L., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., … Anderson, T. J., & Dalrymple-Alford, J. C. (2016). Different PD-MCI criteria and risk of dementia in Parkinson's disease: A 4-year longitudinal study. npj Parkinson's Disease, 2, 15027. doi: 10.1038/npjparkd.2015.27

Journal - Research Article

Alamri, Y., MacAskill, M., Anderson, T., & Benamer, H. (2015). Parkinson's disease in the Gulf countries: An updated review. European Neurology, 74(3-4), 222-225. doi: 10.1159/000442283

Journal - Research Article

Luckey, A. M., Anderson, T., Silverman, M. H., & Webster, G. (2015). Safety, tolerability and pharmacodynamics of a novel immunomodulator, MIS416, in patients with chronic progressive multiple sclerosis. Multiple Sclerosis Journal: Experimental Translational Clinical. doi: 10.1177/2055217315583385

Journal - Research Article

Martin, T., Weatherall, M., Anderson, T. J., & MacAskill, M. R. (2015). A randomized controlled feasibility trial of a specific cueing program for falls management in persons with Parkinson disease and freezing of gait. Journal of Neurologic Physical Therapy, 39, 179-184. doi: 10.1097/npt.0000000000000093

Journal - Research Article

Melzer, T. R., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Watts, R., Keenan, R. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2015). Tracking Parkinson's disease over one year with multimodal magnetic resonance imaging in a group of older patients with moderate disease. PLoS ONE, 10(12), e0143923. doi: 10.1371/journal.pone.0143923

Journal - Research Article

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