Professor Rob Walker

2024

Chapter in Book - Research

Ground, M., Callon, K., Walker, R., Milsom, P., & Cornish, J. (2024). Valvular interstitial cells: Physiology, isolation, and culture. In S. Basu, A. Ranjan & S. Sur (Eds.), Technologies in cell culture: A journey from basics to advanced applications. London, UK: InTech Open. doi: 10.5772/intechopen.112649

Journal - Research Article

Cashmore, B., Tunnicliffe, D. J., Palmer, S., Blythen, L., Boag, J., Kostner, K., … Patu, M., … Walker, R., on behalf of the CARI Guidelines Steering Committee. (2024). Australian and New Zealand Living Guideline cholesterol-lowering therapy for people with chronic kidney disease (CARI Guidelines): Reducing the evidence-practice gap. Nephrology, 29(8), 495-509. doi: 10.1111/nep.14295

Francis, A., Wainstein, M., Irish, G., Hafidz, M. I. A., Chen, T., Cho, Y., … and the Regional Board and ISN-GKHA Team Authors, including Walker, R. (2024). Capacity for the management of kidney failure in the International Society of Nephrology Oceania and South East Asia (OSEA) region: Report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA). Kidney International Supplements, 13, 110-122. doi: 10.1016/j.kisu.2024.01.004

Wang, D.-X., Bao, S.-Y., Song, N.-N., Chen, W.-Z., Ding, X.-Q., Walker, R. J., & Fang, Y. (2024). FTO-mediated m6A mRNA demethylation aggravates renal fibrosis by targeting RUNX1 and further enhancing PI3K/AKT pathway. FASEB Journal, 38, e23436. doi: 10.1096/fj.202302041R

Journal - Research Other

Fordyce, A. M., Heenan-Vos, F., Putt, T. L., Donnellen, S., Schollum, J. B. W., & Walker, R. J. (2024). An unusual case of Herbaspirillum huttiense bacteraemia in a haemodialysis patient. Nephrology. Advance online publication. doi: 10.1111/nep.14385

Florance, J. A., Schollum, J. B. W., Pomeranc, A., Endre, Z. H., & Walker, R. J. (2024). Autosomal dominant hypercalciuric hypocalcaemia: The calcium-sensing receptor in renal calcium homeostasis and the impact of renal transplantation. Internal Medicine Journal. Advance online publication. doi: 10.1111/imj.16403

Wilson, L. C., Ward, J., Wright, D. F. B., Green, S. C., Stocker, S. L., Putt, T. L., Schollum, J. B. W., & Walker, R. J. (2024). The impact of peritoneal dialysis on oxypurinol and urate elimination in people with gout. Nephrology, 29, 547-550. doi: 10.1111/nep.14306

Conference Contribution - Verbal presentation and other Conference outputs

Walker, R. (2024, March). Chronic kidney disease and CVD risk. Verbal presentation at the Goodfellow Symposium: Skills for Next Monday, Auckland, New Zealand.

2023

Journal - Research Article

Strand, V., Jayne, D. R. W., Horomanski, A., Yue, H., Bekker, P., Merkel, P. A., on behalf of the ADVOCATE Study Group, including Walker, R. (2023). The impact of treatment with avacopan on health-related quality of life in antineutrophil cytoplasmic antibody-associated vasculitis: A post-hoc analysis of data from the ADVOCATE trial. Lancet Rheumatology, 5(8), e451-e460. doi: 10.1016/S2665-9913(23)00092-9

Au, A. Y. M., Mantik, K., Bahadory, F., Stathakis, P., Guiney, H., Erlich, J., Walker, R., Poulton, R., … Endre, Z. H. (2023). Plasma arginine metabolites in health and chronic kidney disease. Nephrology Dialysis Transplantation, 38, 2767-2775. doi: 10.1093/ndt/gfad108

Hegerty, K., Jaure, A., Scholes-Robertson, N., Howard, K., Ju, A., Evangelidis, N., … on behalf of INCremental dialysis to improve Health outcomes people starting Hemodialysis (INCH-HD) investigators including, Walker, R., Wyeth, E., & Wilson, L. (2023). Australian workshops on patients’ perspectives on hemodialysis and incremental start. Kidney International Reports, 8, 478-488. doi: 10.1016/j.ekir.2022.11.012

Chan, R., Walker, R. J., Samaranayaka, A., & Schollum, J. B. W. (2023). Long-term impact of early non-infectious complications at the initiation of peritoneal dialysis. Peritoneal Dialysis International, 43(1), 53-63. doi: 10.1177/08968608221132647

Talbot, B., Cass, A., Walker, R., Hooi, L., Jardine, M., Jung, M., … Gallagher, M. (2023). Comparing survival in patients with chronic kidney disease across three countries: Results from the study of heart and renal protection-extended review. Nephrology, 28, 36-43. doi: 10.1111/nep.14127

Guiney, H., Walker, R., Broadbent, J., Caspi, A., Goodin, E., Kokaua, J., … Robertson, S., Theodore, R., Poulton, R., & Endre, Z. (2023). Kidney-function trajectories from young adulthood to midlife: Identifying risk strata and opportunities for intervention. Kidney International Reports, 8, 51-63. doi: 10.1016/j.ekir.2022.10.005

Journal - Research Other

Perl, J., Brown, E. A., Chan, C. T., Couchoud, C., Davies, S. J., Kazancioğlu, R., … for Conference Participants, including Walker, R. J. (2023). Home dialysis: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) controversies conference [Conference report]. Kidney International, 103, 842-858. doi: 10.1016/j.kint.2023.01.006

Wu, H., Chinnadurai, R., Walker, R. J., & Tennankore, K. K. (2023). Is it time to integrate frailty assessment in onconephrology. Cancers, 15, 1674. doi: 10.3390/cancers15061674

Other Research Output

CARI Living Guideline Lipid Working Group, including Walker, R., Palmer, S. & Patu, M. (2023). CARI Living Guidelines: Management of cholesterol-lowering therapy in people with chronic kidney disease. 38p. Retrieved from https://www.cariguidelines.org/

2022

Journal - Research Article

Mehta, P. M., Gimenez, G., Walker, R. J., & Slatter, T. L. (2022). Reduction of lithium induced interstitial fibrosis on co-administration with amiloride. Scientific Reports, 12(1), 14598. doi: 10.1038/s41598-022-18825-1

Heath, L., Egan, R., Iosua, E., Walker, R., Ross, J., & MacLeod, R. (2022). Palliative and end of life care in undergraduate medical education: A survey of New Zealand medical schools. BMC Medical Education, 22(1), 530. doi: 10.1186/s12909-022-03593-3

Ground, M., Waqanivavalagi, S., Park, Y.-E., Callon, K., Walker, R., Milsom, P., & Cornish, J. (2022). Fibroblast growth factor 2 inhibits myofibroblastic activation of valvular interstitial cells. PLoS ONE, 17(6), e0270227. doi: 10.1371/journal.pone.0270227

Butcher, E., Walker, R., Wyeth, E., Samaranayaka, A., Schollum, J., & Derrett, S. (2022). Health-related quality of life and disability among older New Zealanders with kidney failure: A prospective study. Canadian Journal of Kidney Health & Disease, 9, 1-14. doi: 10.1177/20543581221094712

Tafuna'i, M., Turner, R., Matalavea, B., Voss, D., Hazelman, L., Richards, R., & Walker, R. (2022). Results of a community-based screening programme for chronic kidney disease and associated risk factors, (obesity, diabetes and hypertension) in a Samoan cohort. BMJ Open, 12(4), e056889. doi: 10.1136/bmjopen-2021-056889

Tafuna'i, M., Turner, R. M., Richards, R., Sopoaga, F., & Walker, R. (2022). The prevalence of chronic kidney disease in Samoans living in Auckland, New Zealand. Nephrology, 27(3), 248-259. doi: 10.1111/nep.13990

Journal - Research Other

Wu, H. H. L., Chinnadurai, R., & Walker, R. J. (2022). Is HIF-PHI the answer to tackle ESA hyporesponsiveness in the elderly? Kidney & Dialysis, 2, 446-453. doi: 10.3390/kidneydial2030040

Ground, M., Park, Y. E., Waqanivavalagi, S., Callon, K., Walker, R., Milsom, P., & Cornish, J. (2022). Generating robust human valvular interstitial cell cultures: Protocol and considerations. Journal of Molecular & Cellular Cardiology, 173, 118-126. doi: 10.1016/j.yjmcc.2022.10.008

Conference Contribution - Published proceedings: Abstract

Chan, R., Walker, R., Samaranayaka, A., & Schollum, J. (2022). Long term impact of early non-infectious complications at the initiation of peritoneal dialysis. Nephrology, 27(Suppl. 1), (pp. 59-60). doi: 10.1111/nep.14099

Mehta, P., Gimenez, G., Slatter, T., & Walker, R. J. (2022). Reduction of lithium induced interstitial fibrosis on co-administration with amiloride. In L. Wilson, H. Harcombe, P. Jayakaran, L. Burga, J. Antony, K. Morgaine, M. Garelja, A. Middleton, M. Anwar & T. Milne (Eds.), Proceedings of the 262nd Otago Medical School Research Society (OMSRS) Meeting: Research Staff Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839

Conference Contribution - Verbal presentation and other Conference outputs

Walker, R. (2022, December). Kidney-function trajectories from young adulthood to midlife: Identifying risk strata and opportunities for intervention. Verbal presentation at the Kidney in Health and Disease Research Network 47th Research Meeting, Dunedin, New Zealand.

Ground, M., Waqanivavalagi, S., Milsom, P., Walker, R., & Cornish, J. (2022, August). FGF-2 reverses myofibroblastic activation of diseased valvular interstitial cells. Verbal presentation at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

2021

Journal - Research Article

Leader, C. J., Wilkins, G. T., & Walker, R. J. (2021). The effect of spironolactone on cardiac and renal fibrosis following myocardial infarction in established hypertension in the transgenic Cyp1a1Ren2 rat. PLoS ONE, 16(11), e0260554. doi: 10.1371/journal.pone.0260554

McLean, R. M., Xie, Z., Nelson, V., Nosa, V., Po’e-Tofaeono, A., Walker, R., & Wyeth, E. H. (2021). Experiences of New Zealand haemodialysis patients in relation to food and nutrition management: A qualitative study. Nutrients, 13(7), 2299. doi: 10.3390/nu13072299

Zhou, Z., Jardine, M. J., Li, Q., Neuen, B. L., Cannon, C. P., de Zeeuw, D., … CREDENCE Trial Investigators, including Walker, R. (2021). Effect of SGLT2 inhibitors on stroke and atrial fibrillation in diabetic kidney disease: Results from the CREDENCE trial and meta-analysis. Stroke, 52, 1545-1556. doi: 10.1161/STROKEAHA.120.031623

Shettigar, R., Samaranayaka, A., Schollum, J. B. W., Wyeth, E. H., Derrett, S., & Walker, R. J. (2021). Predictors of health deterioration among older New Zealanders undergoing dialysis: A three-year accelerated longitudinal cohort study. Canadian Journal of Kidney Health & Disease, 8. doi: 10.1177/20543581211022207

Ground, M., Waqanivavalagi, S., Walker, R., Milsom, P., & Cornish, J. (2021). Models of immunogenicity in preclinical assessment of tissue engineered heart valves. Acta Biomaterialia, 133, 102-113. doi: 10.1016/j.actbio.2021.05.049

Jayne, D. R. W., Merkel, P. A., Schall, T. J., Bekker, P., for the ADVOCATE Study Group, including Walker, R. (2021). Avacopan for the treatment of ANCA-associated vasculitis. New England Journal of Medicine, 384, 599-609. doi: 10.1056/NEJMoa2023386

Heath, L., Egan, R., Ross, J., Iosua, E., Walker, R., & MacLeod, R. (2021). Preparing nurses for palliative and end of life care: A survey of New Zealand nursing schools. Nurse Education Today, 100, 104822. doi: 10.1016/j.nedt.2021.104822

Kuan, I. H. S., Wilson, L. C., Leishman, J. C., Cosgrove, S., Walker, R. J., Putt, T. L., Schollum, J. B. W., & Wright, D. F. B. (2021). Metformin doses to ensure efficacy and safety in patients with reduced kidney function. PLoS ONE, 16(2), e0246247. doi: 10.1371/journal.pone.0246247

Shoemaker, L. N., Wilson, L. C., Lucas, S. J. E., Machado, L., Walker, R. J., & Cotter, J. D. (2021). Indomethacin markedly blunts cerebral perfusion and reactivity, with little cognitive consequence in healthy young and older adults. Journal of Physiology, 599(4), 1097-1113. doi: 10.1113/jp280118

Journal - Research Other

Jennings, M. J., Molteno, T. C. A., Walker, R. J., Bedford, J. J., Leader, J. P., & Poole, T. (2021). Transmission electron microscopy tilt-series data from in-situ chondrocyte primary cilia [Data descriptor]. Data, 6(11), 118. doi: 10.3390/data6110118

Shettigar, R., Schollum, J., Putt, T., Chan, L., Lau, M., & Walker, R. (2021). Renal manifestations of syphilis [Brief communication]. Internal Medicine Journal, 51(7), 1160-1167. doi: 10.1111/imj.15407

Pradhan, S., Duffull, S. B., Wilson, L. C., Kuan, I. H. S., Walker, R. J., Putt, T. L., Schollum, J. B. W., & Wright, D. F. B. (2021). Does the intact nephron hypothesis provide a reasonable model for metformin dosing in chronic kidney disease? British Journal of Clinical Pharmacology, 87, 4871-4879. doi: 10.1111/bcp.14919

Mohd Asarani, N. A., Paddison, J., Walker, R., Downie, M., & Wheeler, B. J. (2021). New‐onset type 1 diabetes complicated by diabetic ketoacidosis and severe sepsis requiring extracorporeal membrane oxygenation and kidney replacement therapy. Journal of Diabetes & Metabolic Disorders, 20, 1075-1079. doi: 10.1007/s40200-021-00736-z

Conference Contribution - Published proceedings: Abstract

Mehta, P., Slatter, T. L., & Walker, R. J. (2021). Amiloride reduces lithium induced interstitial fibrosis and inflammation. Nephrology, 26(Suppl. 2), (pp. 18). doi: 10.1111/nep.13930

Tiku, A., Boudville, N., Brown, F., Cass, A., Clarke, P., Day, R., … Palmer, S., … Walker, R., … Dalbeth, N. (2021). Urate-lowering therapy for prevention of gout: Prespecified analyses from the CKD-FIX trial. Arthritis & Rheumatology, 73(Suppl. 9), (pp. 1372-1373). doi: 10.1002/art.41966

Other Research Output

Walker, R. (October, 2021). Gout through the ages. Otago Medical School Alumni Association (OMSAA) History of Medicine and Science Talks, Dunedin, New Zealand. Retrieved from https://www.youtube.com/watch?v=AcmM79gdGYk

2020

Journal - Research Article

Heath, L., Egan, R., Ross, J., Iosua, E., Walker, R., & MacLeod, R. (2020). Teaching palliative care skills. Kai Tiaki Nursing New Zealand, 26(10), 16-17.

Tafuna'i, M., Matalavea, B., Voss, D., Turner, R. M., Richards, R., Sopoaga, F., … Walker, R. (2020). Kidney failure in Samoa. Lancet Regional Health: Western Pacific, 5, 100058. doi: 10.1016/j.lanwpc.2020.100058

Toussaint, N. D., Pedagogos, E., Lioufas, N. M., Elder, G. J., Pascoe, E. M., Badve, S. V., … Walker, R. J., … IMPROVE-CKD Trial Investigators. (2020). A randomized trial on the effect of phosphate reduction on vascular end points in CKD (IMPROVE-CKD). Journal of the American Society of Nephrology, 31, 2653-2666. doi: 10.1681/asn.2020040411

Badve, S. V., Pascoe, E. M., Tiku, A., Boudville, N., Brown, F. G., Cass, A., … Palmer, S. C., … Walker, R. J., … for the CKD-FIX Study Investigators. (2020). Effects of allopurinol on the progression of chronic kidney disease. New England Journal of Medicine, 382(26), 2504-2513. doi: 10.1056/NEJMoa1915833

Leader, C. J., Kelly, D. J., Sammut, I. A., Wilkins, G. T., & Walker, R. J. (2020). Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat. Physiological Reports, 8(10), e14448. doi: 10.14814/phy2.14448

Akerman, A. P., Walker, R. J., Schollum, J. B. W., Putt, T. L., & Wilson, L. C. (2020). Refinement of a protocol to induce reliable muscle cramps in the abductor hallucis. Physiological Measurement, 41, 055003. doi: 10.1088/1361-6579/ab8855

Donnellan, S., Wright, D. F. B., Roberts, J. A., Duffull, S. B., Schollum, J. B. W., Putt, T. L., … Walker, R. J. (2020). The pharmacokinetics of meropenem and piperacillin-tazobactam during sustained low efficiency haemodiafiltration (SLED-HDF). European Journal of Clinical Pharmacology, 76, 239-247. doi: 10.1007/s00228-019-02792-0

Journal - Research Other

Sola, L., Levin, N. W., Johnson, D. W., Pecoits-Filho, R., Aljubori, H. M., Chen, Y., … Walker, R., … Finkelstein, F. O. (2020). Development of a framework for minimum and optimal safety and quality standards for hemodialysis and peritoneal dialysis. Kidney International Supplements, 10(1), e55-e62. doi: 10.1016/j.kisu.2019.11.009

Pecoits-Filho, R., Okpechi, I. G., Donner, J.-A., Harris, D. C. H., Aljubori, H. M., Bello, A. K., … Walker, R., … Johnson, D. W. (2020). Capturing and monitoring global differences in untreated and treated end-stage kidney disease, kidney replacement therapy modality, and outcomes. Kidney International Supplements, 10(1), e3-e9. doi: 10.1016/j.kisu.2019.11.001

Conference Contribution - Published proceedings: Abstract

Shettigar, R., Schollum, J., Derrett, S., Samaranayaka, A., McNoe, B., & Walker, R. (2020). Predictors of health deterioration of older adults after 24 months and 36 months of dialysis therapy. Nephrology, 25(Suppl. 3), (pp. 15). doi: 10.1111/nep.13797

Tiku, A., Pascoe, E., Boudville, N., Cass, A., Dalbeth, N., Day, R., … Palmer, S., … Walker, R., … Badve, S. (2020). The effects of allopurinol on the progression of chronic kidney disease according to diabetic kidney disease at baseline: Pre-specified analyses of the CKD-FIX trial. Nephrology, 25(Suppl. 3), (pp. 60). doi: 10.1111/nep.13799

Tiku, A., Pascoe, E., Boudville, N., Cass, A., Dalbeth, N., Day, R., … Palmer, S., … Walker, R., … Badve, S. (2020). The effects of allopurinol on the progression of chronic kidney disease according to baseline serum urate level: Results from post hoc analyses of the CKD-FIX trial. Nephrology, 25(Suppl. 3), (pp. 60-61). doi: 10.1111/nep.13799

Tiku, A., Pascoe, E., Boudville, N., Cass, A., Dalbeth, N., Day, R. O., … Palmer, S., … Walker, R. J., … Badve, S. (2020). The effects of allopurinol on the progression of chronic kidney disease according to baseline kidney function: Pre-specified analyses of the CKD-FIX trial. Nephrology, 25(Suppl. 3), (pp. 60). doi: 10.1111/nep.13799

Tiku, A., Pascoe, E., Boudville, N., Cass, A., Dalbeth, N., Day, R. O., … Palmer, S., … Walker, R. J., … Badve, S. (2020). The effects of allopurinol on the progression of chronic kidney disease according to albuminuria at baseline: Results from pre-specified analyses of the CKD-FIX trial. Nephrology, 25(Suppl. 3), (pp. 29). doi: 10.1111/nep.13798

Shoemaker, L. N., Wilson, L. C., Lucas, S. J. E., Machado, L., Walker, R. J., & Cotter, J. D. (2020). Effect of cerebral blood flow on cognition across healthy adulthood. FASEB Journal, 34(Suppl. 1). doi: 10.1096/fasebj.2020.34.s1.06931

Talbot, B., Sukkar, L., Smyth, B., Jun, M., Jardine, M., Cass, A., Walker, R., … Gallagher, M. (2020). Comparing survival in patients with chronic kidney disease across three countries: Results from the study of heart and renal protection: Extended review (SHARP-ER). Kidney International Reports, 5(3, Suppl.), (pp. S250). doi: 10.1016/j.ekir.2020.02.646

Other Research Output

CARI Living Guideline Lipid Work Group including Walker, R., Palmer, S. & Patu, M. (2020). CARI Guidelines: Management of lipid-lowering therapy in CKD. 42p. Retrieved from https://app.magicapp.org/summary/guideline_4689.html

2019

Journal - Research Article

Leader, C. J., Moharram, M., Coffey, S., Sammut, I. A., Wilkins, G., & Walker, R. J. (2019). Myocardial global longitudinal strain: An early indicator of cardiac interstitial fibrosis modified by spironolactone, in a unique hypertensive rat model. PLoS ONE, 14(8), e0220837. doi: 10.1371/journal.pone.0220837

Kuan, I. H. S., Savage, R. L., Duffull, S. B., Walker, R. J., & Wright, D. F. B. (2019). The association between metformin therapy and lactic acidosis. Drug Safety, 42, 1449-1469. doi: 10.1007/s40264-019-00854-x

Walker, R. J., Tafunai, M., & Krishnan, A. (2019). Chronic kidney disease in New Zealand Māori and Pacific people. Seminars in Nephrology, 39(3), 297-299. doi: 10.1016/j.semnephrol.2019.03.001

McNoe, B., Schollum, J. B. W., Derrett, S., Marshall, M. R., Henderson, A., Samaranayaka, A., & Walker, R. J. (2019). Recruitment and participant baseline characteristics in the dialysis outcomes in those aged 65 years or older study. BMC Nephrology, 20, 137. doi: 10.1186/s12882-019-1328-8

Harris, D. C. H., Davies, S. J., Finkelstein, F. O., Jha, V., Donner, J.-A., Abraham, G., … on behalf of the Working Groups of the International Society of Nephrology's 2nd Global Kidney Health Summit, including Walker, R. (2019). Increasing access to integrated ESKD care as part of universal health coverage. Kidney International, 95(4, Suppl.), S1-S33. doi: 10.1016/j.kint.2018.12.005

Fuimaono, R. A., Sopoaga, F., Derrett, S., & Walker, R. (2019). The perspectives of Samoan patients and health professionals about access to renal services in New Zealand. New Zealand Medical Journal, 132(1492), 11-18. Retrieved from https://www.nzma.org.nz/journal

Hurcombe, J. A., Hartley, P., Lay, A. C., Ni, L., Bedford, J. J., Leader, J. P., … Walker, R. J., … Coward, R. J. M. (2019). Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function. Nature Communications, 10, 403. doi: 10.1038/s41467-018-08235-1

Pradhan, S., Duffull, S. B., Walker, R. J., & Wright, D. F. B. (2019). The intact nephron hypothesis as a model for renal drug handling. European Journal of Clinical Pharmacology, 75(2), 147-156. doi: 10.1007/s00228-018-2572-8

Lloyd, H., Li, G., Tomlin, A., Tilyard, M. W., Walker, R., & Schollum, J. (2019). Prevalence and risk factors for chronic kidney disease in primary health care in the Southern Region of New Zealand. Nephrology, 24(3), 308-315. doi: 10.1111/nep.13395

Journal - Research Other

Leader, J., Bedford, J., & Walker, R. J. (2019). Drowning in data: Early responses of renal cortical collecting duct cells to lithium. Annals of Translational Medicine, 8(Suppl. 8), S322. doi: 10.21037/atm.2019.09.120

Sukkar, L., Talbot, B., Jun, M., Dempsey, E., Walker, R., Hooi, L., … on behalf of the SHARP-ER Study Collaborators, including McGregor, D., & Ellis, G. (2019). Protocol for the study of heart and renal protection-extended review: Additional 5-year follow-up of the Australian, New Zealand, and Malaysian SHARP cohort. Canadian Journal of Kidney Health & Disease, 6, 1-11. doi: 10.1177/2054358119879896

Hoye, N. A., Wilson, L. C., Jardine, D. L., & Walker, R. J. (2019). Sympathetic overactivity in dialysis patients: Underappreciated and clinically consequential. Seminars in Dialysis, 32, 255-265. doi: 10.1111/sdi.12756

Conference Contribution - Published proceedings: Abstract

Shettigar, R., Schollum, J., Putt, T., & Walker, R. (2019). Acute kidney injury in patients with solid organ and haematological malignancies: A single centre experience. Kidney International Reports, 4(7, Suppl.), (pp. S149). doi: 10.1016/j.ekir.2019.05.384

Shettigar, R., Schollum, J., Walker, R., & Putt, T. (2019). Renal transplantation in a patient with familial syndrome of hypocalcemia with hypercalciuria. Kidney International Reports, 4(7, Suppl.), (pp. S381). doi: 10.1016/j.ekir.2019.05.988

Shettigar, R., Putt, T., Walker, R., & Schollum, J. (2019). Recurrence of MPO vasculitis in the immediate post transplant period. Kidney International Reports, 4(7, Suppl.), (pp. S381). doi: 10.1016/j.ekir.2019.05.989

Leader, C., Moharram, M., Sammut, I., Coffey, S., Wilkins, G., & Walker, R. (2019). The effect of spironolactone in a rat model of established hypertension. Kidney International Reports, 4(7, Suppl.), (pp. S146-S147). doi: 10.1016/j.ekir.2019.05.377

Conference Contribution - Poster Presentation (not in published proceedings)

Shoemaker, L. N., Wilson, L. C., Lucas, S. J. E., Machado, L., Walker, R. J., & Cotter, J. D. (2019, September). Effect of cerebral blood flow on cognition across healthy adulthood. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2018

Journal - Research Article

Leader, C. J., Clark, B. J., Hannah, A. R., Sammut, I. A., Wilkins, G. T., & Walker, R. J. (2018). Breeding characteristics and dose-dependent blood pressure responses of transgenic Cyp1a1-Ren2 rats. Comparative Medicine, 68(5), 360-366. doi: 10.30802/AALAS-CM-17-18000026

Samaranayaka, S., Walker, R. J., Samaranayaka, A., Derrett, S., & Schollum, J. B. W. (2018). Medication exposure and health outcomes in older patients with end-stage kidney disease: A prospective study undertaken in New Zealand. Drugs & Aging, 35, 1005-1015. doi: 10.1007/s40266-018-0582-y

Storey, B. C., Staplin, N., Haynes, R., Reith, C., Emberson, J., Herrington, W. G., … Walker, R., … on behalf of the SHARP Collaborative Group. (2018). Lowering LDL cholesterol reduces cardiovascular risk independently of presence of inflammation. Kidney International, 93(4), 1000-1007. doi: 10.1016/j.kint.2017.09.011

Mafham, M. M., Staplin, N., Emberson, J., Haynes, R., Herrington, W., Reith, C., … Walker, R., … on behalf of the SHARP Collaborative Group. (2018). Prognostic utility of estimated albumin excretion rate in chronic kidney disease: Results from the Study of Heart and Renal Protection. Nephrology Dialysis Transplantation, 33(2), 257-264. doi: 10.1093/ndt/gfw396

Kalita-De Croft, P., Bedford, J. J., Leader, J. P., & Walker, R. J. (2018). Amiloride modifies the progression of lithium-induced renal interstitial fibrosis. Nephrology, 23(1), 20-30. doi: 10.1111/nep.12929

Journal - Research Other

Donnellan, S., Walker, R., Putt, T., & Schollum, J. (2018). Unusual case of renal parenchymal urine leak post-transplantation. Nephrology, 23(12), 1152. doi: 10.1111/nep.13262

Conference Contribution - Published proceedings: Abstract

Pearson, G. M., & Walker, R. (2018). Mortality and quality of life in elderly patients on dialysis in New Zealand: Results from the Dialysis Outcomes in the ≥65s Study (DOS65+). Journal of the American Geriatrics Society, 66(Suppl. 2), (pp. S185). doi: 10.1111/jgs.15376

Leader, C., Moharram, M., Sammut, I., Coffey, S., Wilkins, G., & Walker, R. (2018). The effect of spironolactone on renal injury (fibrosis) in a hypertensive transgenic Cyp1aRen2 rat model. Nephrology, 23(Suppl. 3), (pp. 44). doi: 10.1111/nep.13441

Talbot, B., Sukkar, L., Smyth, B., Jun, M., Jardine, M., Cass, A., Walker, R., … Gallagher, M. (2018). Cause of death varies across Australia, New Zealand and Malaysia in those on renal replacement therapy: Results from the study of heart and renal protection-extended review (SHARP-ER). Nephrology, 23(Suppl. 3), (pp. 29). doi: 10.1111/nep.13441

Jun, M., Sukkar, L., Jardine, M., Talbot, B., Cass, A., Reith, C., Walker, R., & Gallagher, M. (2018). Assessing baseline medication use in chronic kidney disease: An analysis of the SHARP-ER study. Nephrology, 23(Suppl. 3), (pp. 25). doi: 10.1111/nep.13441

Conference Contribution - Verbal presentation and other Conference outputs

Mugloo, S., Ashley, Z., Leader, C., Bahn, A., Sammut, I. A., Walker, R., McDonald, F. J., & Fronius, M. (2018, August). Characterising the role of vascular ENaC for blood pressure regulation. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Other Research Output

Iodinated Contrast Media Guideline Working Group, including Walker, R.. (2018). The Royal Australian and New Zealand College of Radiologists Iodinated Contrast Media Guideline (V2.3). 38p. Sydney, Australia: RANZCR. Retrieved from https://www.ranzcr.com/

2017

Chapter in Book - Research

Endre, Z. H., & Walker, R. J. (2017). Biomarkers of cardiovascular risk in chronic kidney disease. In C. L. Edelstein (Ed.), Biomarkers of kidney disease. (2nd ed.) (pp. 485-511). London, UK: Elsevier. doi: 10.1016/B978-0-12-803014-1.00011-X

Journal - Research Article

Reith, C., Staplin, N., Herrington, W. G., Stevens, W., Emberson, J., Haynes, R., … on behalf of the SHARP Collaborative Group, including Walker, R., McGregor, D., Schollum, J., & Ellis, G. (2017). Effect on non-vascular outcomes of lowering LDL cholesterol in patients with chronic kidney disease: Results from the Study of Heart and Renal Protection. BMC Nephrology, 18, 147. doi: 10.1186/s12882-017-0545-2

Schlackow, I., Kent, S., Herrington, W., Emberson, J., Haynes, R., Reith, C., … on behalf of the SHARP Collaborative Group, including Walker, R., McGregor, D., Schollum, J., & Ellis, G. (2017). A policy model of cardiovascular disease in moderate-to-advanced chronic kidney disease. Heart, 103(23), 1880-1890. doi: 10.1136/heartjnl-2016-310970

Obrador, G. T., Schultheiss, U. T., Kretzler, M., Langham, R. G., Nangaku, M., Pecoits-Filho, R., … Walker, R., … Köttgen, A. (2017). Genetic and environmental risk factors for chronic kidney disease. Kidney International Supplements, 7(2), 88-106. doi: 10.1016/j.kisu.2017.07.004

Todd, A. S., Walker, R. J., MacGinley, R. J., Kelly, J., Merriman, T. R., Major, T. J., & Johnson, R. J. (2017). Dietary sodium modifies serum uric acid concentrations in humans. American Journal of Hypertension, 30(12), 1196-1202. doi: 10.1093/ajh/hpx123

Derrett, S., Samaranayaka, A., Schollum, J. B. W., McNoe, B., Marshall, M. R., Williams, S., Wyeth, E. H., & Walker, R. J. (2017). Predictors of health deterioration among older adults after 12 months of dialysis therapy: A longitudinal cohort study from New Zealand. American Journal of Kidney Diseases, 70(6), 798-806. doi: 10.1053/j.ajkd.2017.06.023

de Groot, T., Doornebal, J., Christensen, B. M., Cockx, S. C., Sinke, A. P., Baumgarten, R., Bedford, J. J., Walker, R. J., … Deen, P. M. T. (2017). Lithium-induced NDI: Acetazolamide reduces polyuria, but does not improve urine concentrating ability. American Journal of Physiology: Renal Physiology, 313(3), F669-F676. doi: 10.1152/ajprenal.00147.2017

Stayner, C., Poole, C. A., McGlashan, S. R., Pilanthananond, M., Brauning, R., Markie, D., … Slobbe, L., … Parker, K., Wiles, A., … Leichter, A., Leask, M., … Jennings, M., Horsfield, J. A., Walker, R. J., & Eccles, M. R. (2017). An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations. Scientific Reports, 7, 1601. doi: 10.1038/s41598-017-01519-4

Hoye, N. A., Wilson, L. C., Wilkins, G. T., Jardine, D. L., Putt, T. L., Samaranayaka, A., Schollum, J. B. W., & Walker, R. J. (2017). Endovascular renal denervation in end-stage kidney disease patients: Cardiovascular protection: A proof-of-concept study. Kidney International Reports, 2(5), 856-865. doi: 10.1016/j.ekir.2017.04.012

Page, M. J., Wyeth, E. H., Samaranayaka, A., McNoe, B., Walker, R. C., Schollum, J., … Walker, R., & Derrett, S. (2017). Accuracy of ethnicity data recorded in hospital-based patient clinical records and the Australia and New Zealand Dialysis and Transplant Registry. New Zealand Medical Journal, 130(1454), 65-71. Retrieved from https://www.nzma.org.nz/journal

Lovell, S., Walker, R. J., Schollum, J. B. W., Marshall, M. R., McNoe, B. M., & Derrett, S. (2017). To dialyse or delay: A qualitative study of older New Zealanders' perceptions and experiences of decision-making, with stage 5 chronic kidney disease. BMJ Open, 7(3), e014781. doi: 10.1136/bmjopen-2016-014781

Herrington, W., Staplin, N., Judge, P. K., Mafham, M., Emberson, J., Haynes, R., … Walker, R., … on behalf of the SHARP Collaborative Group. (2017). Evidence for reverse causality in the association between blood pressure and cardiovascular risk in patients with chronic kidney disease. Hypertension, 69, 314-322. doi: 10.1161/hypertensionaha.116.08386

Kuan, I. H. S., Duffull, S. B., Putt, T. L., Schollum, J. B. W., Walker, R. J., & Wright, D. F. B. (2017). A population pharmacokinetic model for ⁵¹Cr EDTA to estimate renal function. Clinical Pharmacokinetics, 56(6), 671-678. doi: 10.1007/s40262-016-0489-x

Yao, Y., Davis, G., Harrison, J. C., Walker, R. J., & Sammut, I. A. (2017). Renal functional responses in diabetic nephropathy following chronic bilateral renal denervation. Autonomic Neuroscience, 204, 98-104. doi: 10.1016/j.autneu.2016.09.019

Journal - Research Other

Pollock, C., Zuk, A., Anders, H.-J., Reza Ganji, M., Johnson, D. W., Kasiske, B., … Walker, R., … Bonventre, J. V. (2017). The establishment and validation of novel therapeutic targets to retard progression of chronic kidney disease. Kidney International Supplements, 7(2), 130-137. doi: 10.1016/j.kisu.2017.07.008

Ye, J., Hodgson, T., Putt, T., Schollum, J., & Walker, R. (2017). Oxalate nephropathy presenting in exocrine pancreatic insufficiency. Nephrology, 22(8), 658. doi: 10.1111/nep.12858

Conference Contribution - Published proceedings: Abstract

Major, T. J., Cadzow, M. J., Merriman, M. E., Phipps-Green, A. J., Topless, R. K. G., Abhishek, A., … McCormick, S. P. A., … Walker, R. J., … Stamp, L. K., & Merriman, T. R. (2017). Genome-wide association study of gout in 111,098 people of european ancestry. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 547. Retrieved from http://gen2017.w.events4you.currinda.com

Merriman, T. R., Cadzow, M., Merriman, M., Phipps-Green, A., Topless, R., Abhishek, A., … McCormick, S., … Walker, R., … Stamp, L., & Flynn, T. (2017). A genome-wide association study of gout in people of European ancestry. Annals of the Rheumatic Diseases, 76(Suppl. 2), (pp. 383). doi: 10.1136/annrheumdis-2017-eular.5634

Merriman, T. R., Cadzow, M., Merriman, M. E., Phipps-Green, A., Topless, R., Abhishek, A., … McCormick, S., … Walker, R., … Stamp, L. K., & Major, T. (2017). A genome-wide association study of gout in people of European ancestry. Arthritis & Rheumatology, 69(Suppl. 10), 1104. doi: 10.1002/art.40321

Putt, T., Schollum, J., Walker, R., Leishman, J., Duffull, S., & Wright, D. (2017). Pharmacokinetics of Metformin in settings of KCD. Nephrology, 22(Suppl. 3), (pp. 45). doi: 10.1111/nep.13104

Conference Contribution - Verbal presentation and other Conference outputs

Todd, A. S., Walker, R. J., MacGinley, R. J., Kelly, J., Merriman, T. R., Major, T. J., & Johnson, R. J. (2017, August-September). Can dietary sodium modify serum uric acid concentrations in humans? Verbal presentation at the Dietitians NZ National Professional Development Meeting, Wellington, New Zealand.

Mugloo, S., Ashley, Z., Leader, C., Bahn, A., Sammut, I. A., Walker, R., McDonald, F. J., & Fronius, M. (2017, September). Hypertension is associated with increased ENaC expression in the arteries of Cyp1a1-Ren2 rats. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2016

Journal - Research Article

Marti, H.-P., Jeffs, A., Scherer, A., Leader, J., Leader, C., Bedford, J., & Walker, R. (2016). Renal fibrosis mRNA classifier: Validation in experimental lithium-induced interstitial fibrosis in the rat kidney. PLoS ONE, 11(12), e0168240. doi: 10.1371/journal.pone.0168240

Staplin, N., Haynes, R., Herrington, W. G., Reith, C., Cass, A., Fellström, B., … Walker, R., … on behalf of the SHARP Collaborative Group. (2016). Smoking and adverse outcomes in patients with CKD: The Study of Heart and Renal Protection (SHARP). American Journal of Kidney Diseases, 68(3), 371-380. doi: 10.1053/j.ajkd.2016.02.052

Mandic, S., Stevens, E., Hodge, C., Brown, C., Walker, R., Body, D., … Nye, E. R., & Williams, M. J. A. (2016). Long-term effects of cardiac rehabilitation in elderly individuals with stable coronary artery disease. Disability & Rehabilitation, 38(9), 837-843. doi: 10.3109/09638288.2015.1061611

Journal - Research Other

Young, G., Putt, T., Schollum, J., & Walker, R. (2016). Tumoural calcinosis in a young woman. Nephrology, 21(3), 267. doi: 10.1111/nep.12571

Conference Contribution - Published proceedings: Abstract

Ashley, Z., Leader, C., Sammut, I., McDonald, F., Walker, R., & Fronius, M. (2016). The flow detection role of the vascular epithelial sodium channel (ENaC) in an experimental model of hypertension: The novel target for spironolactone therapy? Journal of Hypertension, 34(Suppl. 2), (pp. e103). [Abstract]

Leader, C., Sammut, I., Ashley, Z., Wilkins, G., & Walker, R. (2016). Development of renal injury following myocardial infarction in a hypertensive transgenic Cyp1a1Ren2 rat. Nephrology, 21(Suppl. 2), (pp. 154). doi: 10.1111/nep.12888

Hoye, N. A., Baldi, J. C., Jardine, D. L., Schollum, J. B., Wilkins, G. T., Wilson, L. C., & Walker, R. J. (2016). Delayed but sustained blood pressure and sympathetic reduction one year after renal denervation in dialysis patents. Proceedings of the European Renal Association and the European Dialysis and Transplant Association (ERA-EDTA) 53rd Congress. MO058. Retrieved from http://www.abstracts2view.com/era_archive/

Conference Contribution - Poster Presentation (not in published proceedings)

Mugloo, S., Leader, C., Sammut, I. A., Walker, R., McDonald, F. J., & Fronius, M. (2016, August). Characterising ENaC expression in vasculature. Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Li, G., Lloyd, H. S., Schollum, J., Tilyard, M. W., Tomlin, A., & Walker, R. (2016, December). The prevalence of chronic kidney disease in primary health care in the southern region of New Zealand. Verbal presentation at the Joint International Meeting of the Renal Scientists of the Australia and New Zealand Society of Nephrology and the Kidney in Health and Disease Network: Translational Medicine: Innovations in Renal Research, Blenheim, New Zealand.

Putt, T., Schollum, J., Walker, R., Leishman, J., Duffull, S., & Wright, D. (2016, December). Pharmacokinetics of metformin in setting of CKD. Verbal presentation at the Joint International Meeting of the Renal Scientists of the Australia and New Zealand Society of Nephrology and the Kidney in Health and Disease Network: Translational Medicine: Innovations in Renal Research, Blenheim, New Zealand.

Wilson, L. C., Wilkins, G. T., Cotter, J. D., Manning, P., & Walker, R. J. (2016, December). What aspects of altered cerebral vascular function can be implicated in the elevated risk of cerebrovascular disease in those with type 2 diabetes: Can six-months of high-intensity interval training improve cerebral vascular function? Verbal presentation at the Joint International Meeting of the Renal Scientists of the Australia and New Zealand Society of Nephrology and the Kidney in Health and Disease Network: Translational Medicine: Innovations in Renal Research, Blenheim, New Zealand.

Leader, J., Bedford, J., van der Tholen, L., Weiner, D., & Walker, R. (2016, December). Lithium in the renal cortex. Verbal presentation at the Joint International Meeting of the Renal Scientists of the Australia and New Zealand Society of Nephrology and the Kidney in Health and Disease Network: Translational Medicine: Innovations in Renal Research, Blenheim, New Zealand.

Mugloo, S., Ashley, Z., Leader, C., Bahn, A., Sammut, I., Walker, R., McDonald, F., & Fronius, M. (2016, December). Epithelial Sodium Channel (ENaC): An emerging regulator of vascular physiology. Verbal presentation at the Joint International Meeting of the Renal Scientists of the Australia and New Zealand Society of Nephrology and the Kidney in Health and Disease Network: Translational Medicine: Innovations in Renal Research, Blenheim, New Zealand.

Ashley, Z., Leader, C., Sammut, I., McDonald, F., Walker, R., & Fronius, M. (2016, December). Role of ENaC in the dysfunction of resistance arteries in hypertension with/without the confounding factor of myocardial infarction. Verbal presentation at the Joint International Meeting of the Renal Scientists of the Australia and New Zealand Society of Nephrology and the Kidney in Health and Disease Network: Translational Medicine: Innovations in Renal Research, Blenheim, New Zealand.

Leader, C., Ashley, Z., Sammut, I., Wilkins, G., & Walker, R. (2016, December). Kidney injury following myocardial infarction in a hypertensive transgenic rat. Verbal presentation at the Joint International Meeting of the Renal Scientists of the Australia and New Zealand Society of Nephrology and the Kidney in Health and Disease Network: Translational Medicine: Innovations in Renal Research, Blenheim, New Zealand.

Jennings, M., Ashley, Z., Leader, C., McDonald, F., Sammut, I., Walker, R., & Fronius, M. (2016, December). The ultrastructure of mesenteric arteries in a hypertensive rat model. Verbal presentation at the Joint International Meeting of the Renal Scientists of the Australia and New Zealand Society of Nephrology and the Kidney in Health and Disease Network: Translational Medicine: Innovations in Renal Research, Blenheim, New Zealand.

Yao, Y., Harrison, J. C., Davis, G., Walker, R. J., & Sammut, I. A. (2016, August). Renal denervation in diabetes. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.

Walker, R. (2016, March-April). Renal function. Verbal presentation at the New Zealand Rural General Practice Network (NZRGPN) National Rural Health Conference, Dunedin, New Zealand.

2015

Journal - Research Article

Egan, R., Wood, S., MacLeod, R., & Walker, R. (2015). Spirituality in renal supportive care: A thematic review. Healthcare, 3(4), 1174-1193. doi: 10.3390/healthcare3041174

Flynn, T. J., Cadzow, M., Dalbeth, N., Jones, P. B., Stamp, L. K., Harré Hindmarsh, J., Todd, A. S., Walker, R. J., Topless, R., & Merriman, T. R. (2015). Positive association of tomato consumption with serum urate: Support for tomato consumption as an anecdotal trigger of gout flares. BMC Musculoskeletal Disorders, 16, 196. doi: 10.1186/s12891-015-0661-8

Chembo, C. L., Marshall, M. R., Williams, L. C., Walker, R. J., Lynn, K. L., Irvine, J., & Pilmore, H. L. (2015). Long-term outcomes for primary glomerulonephritis: New Zealand Glomerulonephritis study. Nephrology, 20(12), 899-907. doi: 10.1111/nep.12538

Marshall, M. R., Young, B. A., Fox, S. J., Cleland, C. J., Walker, R. J., Maskane, I., & Herold, A. M. (2015). The home hemodialysis hub: Physical infrastructure and integrated governance structure. Hemodialysis International, 19(Suppl. 1), S8-S22. doi: 10.1111/hdi.12273

Mandic, S., Body, D., Barclay, L., Walker, R., Nye, E. R., Grace, S. L., & Williams, M. J. A. (2015). Community-based cardiac rehabilitation maintenance programs: Use and effects. Heart, Lung & Circulation, 24, 710-718. doi: 10.1016/j.hlc.2015.01.014

Journal - Research Other

Slade, H., Mulroy, E., Ussher, J., Putt, T., Schollum, J., & Walker, R. (2015). Sulfadiazine-induced crystal nephropathy: A new ‘old’ problem. Nephrology, 20(7), 511. doi: 10.1111/nep.12428

Mulroy, E., Schollum, J., Putt, T., & Walker, R. (2015). Spontaneous perinephric haemorrhage in an end-stage renal disease patient with multiple renal pseudoaneurysms. Nephrology, 20(6), 441. doi: 10.1111/nep.12415

Conference Contribution - Verbal presentation and other Conference outputs

Kuan, I. H. S., Wright, D. F. B., Putt, T. L., Walker, R. J., & Duffull, S. B. (2015, September). Are conventional methods for measuring isotopic GFR really the gold standard? Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand.

Walker, R. (2015, August). Clinical research: Answering clinic-based questions. Invited presentation at the Inaugural Dunedin School of Medicine Symposium, Dunedin, New Zealand.

2014

Journal - Research Article

Egan, R., MacLeod, R., Tiatia, R., Wood, S., Mountier, J., & Walker, R. (2014). Spiritual care and kidney disease in NZ: A qualitative study with New Zealand renal specialists. Nephrology, 19(11), 708-713. doi: 10.1111/nep.12323

Haynes, R., Lewis, D., Emberson, J., Reith, C., Agodoa, L., Cass, A., … Walker, R., … for the SHARP Collaborative Group. (2014). Effects of lowering LDL cholesterol on progression of kidney disease. Journal of the American Society of Nephrology, 25(8), 1825-1833. doi: 10.1681/ASN.2013090965

Haynes, R., Staplin, N., Emberson, J., Herrington, W. G., Tomson, C., Agodoa, L., … on behalf of the SHARP Collaborative Group, including Walker, R. (2014). Evaluating the contribution of the cause of kidney disease to prognosis in CKD: Results from the Study of Heart and Renal Protection (SHARP). American Journal of Kidney Diseases, 64(1), 40-48. doi: 10.1053/j.ajkd.2013.12.013

Herrington, W., Emberson, J., Staplin, N., Blackwell, L., Fellström, B., Walker, R., … on behalf of the SHARP Investigators. (2014). The effect of lowering LDL cholesterol on vascular access patency: Post hoc analysis of the Study of Heart and Renal Protection. Clinical Journal of the American Society of Nephrology, 9(5), 919. doi: 10.2215/CJN.10371013

Weiner, I. D., Leader, J. P., Bedford, J. J., Verlander, J. W., Ellis, G., Kalita, P., Vos, F., de Jong, S., & Walker, R. J. (2014). Effects of chronic lithium administration on renal acid excretion in humans and rats. Physiological Reports, 2(12), e12242. doi: 10.14814/phy2.12242

Putt, T. L., Duffull, S. B., Schollum, J. B. W., & Walker, R. J. (2014). GFR may not accurately predict aspects of proximal tubule drug handling. European Journal of Clinical Pharmacology, 70(10), 1221-1226. doi: 10.1007/s00228-014-1733-7

Yao, Y., Fomison-Nurse, I. C., Harrison, J. C., Walker, R. J., Davis, G., & Sammut, I. A. (2014). Chronic bilateral renal denervation attenuates renal injury in a transgenic rat model of diabetic nephropathy. American Journal of Physiology: Renal Physiology, 307, F251-F262. doi: 10.1152/ajprenal.00578.2013

Berney-Meyer, L., Hung, N., Slatter, T., Schollum, J. B. W., Kitching, A. R., & Walker, R. J. (2014). Omeprazole-induced acute interstitial nephritis: A possible Th1–Th17-mediated injury? Nephrology, 19(6), 359-365. doi: 10.1111/nep.12226

Hoye, N. A., Baldi, J. C., Putt, T. L., Schollum, J. B., Wilkins, G. T., & Walker, R. J. (2014). Endovascular renal denervation: A novel sympatholytic with relevance to chronic kidney disease. Clinical Kidney Journal, 7(1), 3-10. doi: 10.1093/ckj/sft130

Bose, B., Badve, S. V., Hiremath, S. S., Boudville, N., Brown, F. G., Cass, A., … Palmer, S. C., … Walker, R. J., … Johnson, D. W. (2014). Effects of uric acid-lowering therapy on renal outcomes: A systematic review and meta-analysis. Nephrology Dialysis Transplantation, 29(2), 406-413. doi: 10.1093/ndt/gft378

Journal - Research Other

Schrieber, J., Xu-Holland, A., Walker, R., & Brockway, B. (2014). A rare pulmonary complication of myeloma therapy. Breathe, 10(3), 243-248. doi: 10.1183/20734735.014713

Roy, M., Walker, R., Blyth, P., & Wilkinson, T. (2014). Virtual reality-based assessment of clinical reasoning ability. Medical Education, 48, 1123. doi: 10.1111/medu.12559

Journal - Professional & Other Non-Research Articles

Wanner, C., Tonelli, M., and the Kidney Disease: Improving Global Outcomes Lipid Guideline Development Work Group Members, including Walker, R. J. (2014). KDIGO Clinical Practice Guideline for Lipid Management in CKD: Summary of recommendation statements and clinical approach to the patient. Kidney International, 85, 1303-1309. doi: 10.1038/ki.2014.31

Conference Contribution - Published proceedings: Abstract

Hoye, N. A., Baldi, J. C., Jardine, D. L., Wilkins, G. T., Wilson, L. C., & Walker, R. J. (2014). Endovascular renal denervation in dialysis-dependent renal failure to reduce cardiovascular risk. Nephrology Dialysis Transplantation, 29(Suppl. 3), (pp. iii9). doi: 10.1093/ndt/gfu111

Wilson, G., Hoye, N., Wilson, L., Shoemaker, J. K., Walker, R., Jardine, D., Schollum, J., Wilkins, G., & Baldi, J. C. (2014). Effect of renal ablation on blood pressure and muscle sympathetic nerve activity in chronic kidney disease patients. FASEB Journal, 28(1, Suppl.), LB722. [Abstract]

Putt, T., Duffull, S., Schollum, J., & Walker, R. (2014). GFR may not accurately predict aspects of proximal tubule drug handling. New Zealand Medical Journal, 127(1392). Retrieved from http://www.nzma.org.nz/journal

MacLeod, R., Egan, R., Walker, R., & Wood, S. (2014). Spiritual care and kidney disease in NZ: A qualitative study with New Zealand renal specialists. BMJ Supportive & Palliative Care, 4(Suppl. 1), (pp. A28). doi: 10.1136/bmjspcare-2014-000654.76

Conference Contribution - Verbal presentation and other Conference outputs

Walker, R. (2014, August). Insulin resistance in chronic kidney disease. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2013

Chapter in Book - Research

Walker, R. J., & Endre, Z. H. (2013). Cellular mechanisms of drug nephrotoxicity. In R. J. Alpern, O. W. Moe & M. Caplan (Eds.), Seldin and Giebisch's the kidney: Physiology and pathophysiology (Vol. 2). (5th ed.) (pp. 2889-2932). London, UK: Academic Press. doi: 10.1016/B978-0-12-381462-3.00085-9

Journal - Research Article

Zacharias, M., Mugawar, M., Herbison, G. P., Walker, R. J., Hovhannisyan, K., Sivalingam, P., & Conlon, N. P. (2013). Interventions for protecting renal function in the perioperative period (Review). Cochrane Database of Systematic Reviews, 9, CD003590. doi: 10.1002/14651858.CD003590.pub4

Walker, R., Derrett, S., Campbell, J., Marshall, M. R., Henderson, A., Schollum, J., Williams, S., & McNoe, B. (2013). Dialysis outcomes in those aged ≥ 65 years. BMC Nephrology, 14, 175. doi: 10.1186/1471-2369-14-175

Mandic, S., Hodge, C., Stevens, E., Walker, R., Nye, E. R., Body, D., Barclay, L., & Williams, M. J. A. (2013). Effects of community-based cardiac rehabilitation on body composition and physical function in individuals with stable coronary artery disease: 1.6-year followup. BioMed Research International, 2013, 903604. doi: 10.1155/2013/903604

Mandic, S., Walker, R., Stevens, E., Nye, E. R., Body, D., Barclay, L., & Williams, M. J. A. (2013). Estimating exercise capacity from walking tests in elderly individuals with stable coronary artery disease. Disability & Rehabilitation, 35(22), 1853-1858. doi: 10.3109/09638288.2012.759629

Walker, R. J., Leader, J. P., Bedford, J. J., Gobe, G., Davis, G., Vos, F. E., deJong, S., & Schollum, J. B. W. (2013). Chronic interstitial fibrosis in the rat kidney induced by long-term (6-mo) exposure to lithium. American Journal of Physiology: Renal Physiology, 304(3), F300-F307. doi: 10.1152/ajprenal.00182.2012

Manning, P. J., Sutherland, W. H. F., Williams, S. M., Walker, R. J., Berry, E. A., De Jong, S. A., & Ryalls, A. R. (2013). The effect of lipoic acid and vitamin E therapies in individuals with the metabolic syndrome. Nutrition, Metabolism & Cardiovascular Diseases, 23(6), 543-549. doi: 10.1016/j.numecd.2011.11.006

Journal - Research Other

Baldi, J. C., Manning, P. J., Hofman, P. L., & Walker, R. J. (2013). Comment on: TODAY Study Group. Effects of Metformin, Metformin plus Rosiglitazone, and Metformin plus lifestyle on insulin sensitivity and β-cell function in TODAY. Diabetes Care 2013;36:1749-1757 [Comment]. Diabetes Care, 36, e223. doi: 10.2337/dc13-1426

Phipps, L., & Walker, R. (2013). Educational needs in supportive and end-of-life care. Nephrology, 18(6), 449-452. doi: 10.1111/nep.12065

Walker, R., Fassett, R. G., & Morton, R. L. (2013). Research issues in elderly patients: Gaps in knowledge and suggested directions. Nephrology, 18(6), 439-441. doi: 10.1111/nep.12065

Conference Contribution - Published proceedings: Full paper

Donnelly, J., Cotter, J. D., Walker, R. J., Burgess, K. R., Ainslie, P. N., Stembridge, M., Curtis, A. N., … Lucas, S. J. E. (2013). Acute mountain sickness is not reliably due to fluid regulatory or autonomic stress [Minipaper]. In J. D. Cotter, S. J. E. Lucas & T. Mündel (Eds.), Proceedings of the 15th International Conference on Environmental Ergonomics (ICEE). (pp. 78-80). International Society for Environmental Ergonomics. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Shallcrass, M. D., Lucas, S. J. E., Walker, R. J., & Cotter, J. D. (2013). The role of brain blood flow in respiratory control during exercise. Proceedings of the Sport and Exercise Science New Zealand (SESNZ) Annual Conference: Exercise Science for Health and Sport Performance. (pp. 69). Retrieved from http://www.sesnz.org.nz/Conference/

Putt, T., Duffull, S., Schollum, J., & Walker, R. (2013). Drug dosing in the elderly: The impact of age and tubular function. Nephrology, 18(Suppl. 1), (pp. 42). doi: 10.1111/nep.12121

Kalita, P., Bahn, A., Bedford, J., Leader, J., & Walker, R. (2013). Amiloride modifies renal fibrosis induced by long term lithium treatment. Nephrology, 18(Suppl. 1), (pp. 57). doi: 10.1111/nep.12121

Kalita, P., Bahn, A., Bedford, J., Leader, J., & Walker, R. (2013). Long-term modulation of lithium-induced nephrogenic diabetes isipidus by amiloride. Nephrology, 18(Suppl. 1), (pp. 37). doi: 10.1111/nep.12121

Conference Contribution - Poster Presentation (not in published proceedings)

Jennings, M., Poole, T., & Walker, R. J. (2013, September). Modeling the matrix-cilium-golgi continuum in hyaline chondrocytes by electron tomography. Poster session presented at the Division of Health Sciences Research Forum: Foundations for Health: Otago Health Research, Christchurch, New Zealand.

Kalita, P., Bahn, A., Bedford, J., Leader, J., & Walker, R. (2013, September). Long term amiloride therapy attenuates lithium-induced kidney interstitial fibrosis. Poster session presented at the Division of Health Sciences Research Forum: Foundations for Health: Otago Health Research, Christchurch, New Zealand.

Hoye, N. A., Baldi, C., Jardine, D., Wilkins, G., Wilson, L. C., & Walker, R. (2013, September). Endovascular renal denervation in dialysis-dependent renal failure to reduce cardiovascular risk. Poster session presented at the Division of Health Sciences Research Forum: Foundations for Health: Otago Health Research, Christchurch, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Walker, R. (2013, December). The kidney in health and disease: An overview. Verbal presentation at the University of Otago Triple Theme Research Meeting: The Kidney in Health and Disease, Gut Health Network, Arthritis Research, Dunedin, New Zealand.

Roy, M., Wilkinson, T., Walker, R., & Blyth, P. (2013, June). Virtual reality based clinical cases: A novel method for assessment of competence and clinical reasoning ability. Workshop presentation at the Australian & New Zealand Association for Health Professional Educators (ANZAHPE) Conference: Professional Development of Health Professional Educators, Melbourne, Australia.

2012

Journal - Research Article

Pickering, J. W., Frampton, C. M., Walker, R. J., Shaw, G. M., & Endre, Z. H. (2012). Four hour creatinine clearance is better than plasma creatinine for monitoring renal function in critically ill patients. Critical Care, 16, R107. doi: 10.1186/cc11391

Nejat, M., Pickering, J. W., Devarajan, P., Bonventre, J. V., Edelstein, C. L., Walker, R. J., & Endre, Z. H. (2012). Some biomarkers of acute kidney injury are increased in pre-renal acute injury. Kidney International, 81, 1254-1262. doi: 10.1038/ki.2012.23

Schollum, J. B. W., & Walker, R. J. (2012). Adult urinary tract infection. British Journal of Hospital Medicine, 73(4), 218-223.

Winburn, I. C., Gunatunga, K., McKernan, R. D., Walker, R. J., Sammut, I. A., & Harrison, J. C. (2012). Cell damage following carbon monoxide releasing molecule exposure: Implications for therapeutic applications. Basic & Clinical Pharmacology & Toxicology, 111(1), 31-41. doi: 10.1111/j.1742-7843.2012.00856.x

Berney-Meyer, L., Putt, T., Schollum, J., & Walker, R. (2012). Nephrotoxicity of recreational party drugs. Nephrology, 17(2), 99-103. doi: 10.1111/j.1440-1797.2011.01537.x

Todd, A. S., MacGinley, R. J., Schollum, J. B. W., Williams, S. M., Sutherland, W. H. F., Mann, J. I., & Walker, R. J. (2012). Dietary sodium loading in normotensive healthy volunteers does not increase arterial vascular reactivity or blood pressure. Nephrology, 17(3), 249-256. doi: 10.1111/j.1440-1797.2011.01550.x

Ting, Y.-T., Coates, P. T., Walker, R. J., & McLellan, A. D. (2012). Urinary tubular biomarkers as potential early predictors of renal allograft rejection. Nephrology, 17(1), 11-16. doi: 10.1111/j.1440-1797.2011.01536.x

Vos, F. E., Schollum, J. B., Coulter, C. V., Manning, P. J., Duffull, S. B., & Walker, R. J. (2012). Assessment of markers of glycaemic control in diabetic patients with chronic kidney disease using continuous glucose monitoring. Nephrology, 17(2), 182-188. doi: 10.1111/j.1440-1797.2011.01517.x

Conference Contribution - Published proceedings: Abstract

Lovell, S., Derrett, S., & Walker, R. (2012). Ageing, chronic kidney disease and the decision to dialyse amongst older adults. Proceedings of the New Zealand Geographical Society Conference: 'Connecting Landscapes'. (pp. 92). Retrieved from http://www.nzgs.co.nz/

Anagnostopoulou, A., Walker, R., Jeffs, A., Scherer, A., Bedford, J., Leader, J., … Marti, H.-P. (2012). A subset of metzincins and related genes constitutes a marker of solid organ fibrosis across species. Nephrology Dialysis Transplantation, 27(Suppl. 2), (pp. 44). doi: 10.1093/ndt/gfs198

Pickering, J. W., Frampton, C. M., Walker, R. J., Shaw, G. M., & Endre, Z. H. (2012). 4-hour creatinine clearance in the intensive care unit. Nephrology, 17(Suppl. 2), (pp. 45). doi: 10.1111/j.1440-1797.2012.01631.x

Marti, H. P., Jeffs, A., Scherer, A., Leader, J., Bedford, J., Davis, G., … Walker, R. (2012). Solid organ fibrosis: Evidence for a common pathway across species! Nephrology, 17(Suppl. 2), (pp. 57). doi: 10.1111/j.1440-1797.2012.01632.x

Mandic, S., Walker, R., Stevens, E., Brown, C., Giraldo Ocampo, D., Nye, E. R., … Barclay, L., & Williams, M. J. A. (2012). Correlates of exercise capacity in elderly individuals with and without coronary artery disease. Medicine & Science in Sports & Exercise, 44(5, Suppl. 2), (pp. 403). doi: 10.1249/01.mss.0000417529.22755.ed

Mandic, S., Walker, R., Stevens, E., McIlraith, B., Featherston, S., Nye, E. R., … Barclay, L., & Williams, M. J. A. (2012). Field versus laboratory tests: Exercise capacity estimates in elderly patients with coronary artery disease. Medicine & Science in Sports & Exercise, 44(5, Suppl. 2), (pp. 294). doi: 10.1249/01.mss.0000417529.22755.ed

Lagishetty, C., Putt, T., Guilford, P., Walker, R., & Duffull, S. (2012). Evaluation of biological age indices to predict drug clearance. Proceedings of the Medical Sciences Congress (MedSci). (pp. 23-24). Retrieved from http://www.medscinz.co.nz/QRW2012%20MedSci%20Abstracts.pdf

Mandic, S., Williams, M. J. A., Stevens, E., Brown, C., Nye, E. R., Body, D., … Walker, R. (2012). Long-term effects of cardiac rehabilitation on exercise capacity and cardiovascular function in coronary artery disease. Heart, Lung & Circulation, 21(8), (pp. 499). doi: 10.1016/j.hlc.2012.03.059

Mandic, S., Hodge, C., Stevens, E., Horwood, H., Walker, R., Nye, E. R., … Williams, M. J. A. (2012). Effects of community-based cardiac rehabilitation on physical function and body composition in coronary artery disease: 1.5-year follow-up. Heart, Lung & Circulation, 21(8), (pp. 499-500). doi: 10.1016/j.hlc.2012.03.060

Conference Contribution - Poster Presentation (not in published proceedings)

Jennings, M., Poole, T., & Walker, R. J. (2012, September). Modelling the matrix-cilium-golgi continuum in hyaline chondrocytes by electron tomography. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Poole, C. A., Stayner, C., McGlashan, S. R., Parker, K., Wiles, A., Jennings, M., … Johnstone, A. C., Walker, R. J., & Eccles, M. R. (2012, August). Primary cilia defects in the polycystic kidneys from an ovine model of Meckel Gruber syndrome. Verbal presentation at the Translational Nephrology Conference: From Mechanics to Therapeutics, Queenstown, New Zealand.

Stayner, C., Lett, B., Slobbe, L., Wiles, A., Jennings, M., Markie, D., … Johnstone, A. C., Walker, R. J., Poole, C. A., & Eccles, M. (2012, August). Renal cystic disease: Developing an ovine model. Verbal presentation at the Translational Nephrology Conference: From Mechanics to Therapeutics, Queenstown, New Zealand.

Leader, J., Bedford, J., & Walker, R. (2012, August). Morphological changes in kidneys of rats after long term (six months) exposure to lithium. Verbal presentation at the Translational Nephrology Conference: From Mechanics to Therapeutics, Queenstown, New Zealand.

Kalita, P., Bahn, A., Walker, R., Leader, J., & Bedford, J. (2012, August). Mechanism underlying kidney fibrosis in rats due to prolonged lithium treatment. Verbal presentation at the Translational Nephrology Conference: From Mechanics to Therapeutics, Queenstown, New Zealand.

2011

Journal - Research Article

Vos, F. E., Schollum, J. B., & Walker, R. J. (2011). Glycated albumin is the preferred marker for assessing glycaemic control in advanced chronic kidney disease. NDT Plus, 4(6), 368-375. doi: 10.1093/ndtplus/sfr140

Korell, J., Vos, F. E., Coulter, C. V., Schollum, J. B., Walker, R. J., & Duffull, S. B. (2011). Modeling red blood cell survival data. Journal of Pharmacokinetics & Pharmacodynamics, 38(6), 797-801. doi: 10.1007/s10928-011-9220-6

Endre, Z. H., Pickering, J. W., & Walker, R. J. (2011). Clearance and beyond: The complementary roles of GFR measurement and injury biomarkers in acute kidney injury (AKI). American Journal of Physiology: Renal Physiology, 301(4), F697-F707. doi: 10.1152/ajprenal.00448.2010

Vos, F. E., Schollum, J. B., Coulter, C. V., Doyle, T. C. A., Duffull, S. B., & Walker, R. J. (2011). Red blood cell survival (RBC) in patients on long-term dialysis. Nephrology, 16(Suppl. 1), 74. doi: 10.1111/j.1440-1797.2011.01493_7.x

Bird, S. D., Legge, M., & Walker, R. J. (2011). Thiols stabilize cobblestone morphology of cultured mesothelial cells. Cell Biology International, 35(8), 857-867. doi: 10.1042/CBI20100593

Vos, F. E., Schollum, J. B., Coulter, C. V., Doyle, T. C. A., Duffull, S. B., & Walker, R. J. (2011). Red blood cell survival in long-term dialysis patients. American Journal of Kidney Diseases, 58(4), 591-598. doi: 10.1053/j.ajkd.2011.03.031

Baigent, C., Landray, M. J., Reith, C., Emberson, J., Wheeler, D. C., Tomson, C., … Walker, R., … on behalf of the SHARP Investigators. (2011). The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): A randomised placebo-controlled trial. Lancet, 377(9784), 2181-2192. doi: 10.1016/S0140-6736(11)60739-3

Slade, H., Williams, S. M., Manning, P. J., & Walker, R. J. (2011). High-risk diabetic nephropathy patients: The outcome of evidence-based clinical practice in an outpatient clinic. Diabetes Research & Clinical Practice, 92(3), 356-360. doi: 10.1016/j.diabres.2011.02.022

Li, P. K.-T., Cheung, W. L., Lui, S. L., Blagg, C., Cass, A., Hooi, L. S., … Walker, R., … Yu, A. W.-Y. (2011). Increasing home-based dialysis therapies to tackle dialysis burden around the world: A position statement on dialysis economics from the 2nd Congress of the International Society for Hemodialysis. Hemodialysis International, 15(1), 10-14. doi: 10.1111/j.1542-4758.2010.00512.x

Endre, Z. H., Pickering, J. W., Walker, R. J., Devarajan, P., Edelstein, C. L., Bonventre, J. V., Frampton, C. M., … Shaw, G. M., Henderson, S. J., Nejat, M., Schollum, J. B. W., & George, P. M. (2011). Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney International, 79, 1119-1130. doi: 10.1038/ki.2010.555

Vos, F. E., Manning, P. J., Sutherland, W. H. F., Schollum, J. B., & Walker, R. J. (2011). Anti-inflammatory effect of an insulin infusion in patients on maintenance haemodialysis: A randomized controlled pilot study. Nephrology, 16(1), 68-75. doi: 10.1111/j.1440-1797.2010.01329.x

Conference Contribution - Published proceedings: Abstract

Todd, A., Walker, R., MacGinley, R., Schollum, J., Sutherland, W., Mann, J., & Williams, S. (2011). Sodium and vascular function: Should we be looking beyond blood pressure? Nutrition & Dietetics, 68(Suppl. 2), (pp. 8). [Abstract]

Vos, F. E., Schollum, J. B., Coulter, C. V., Manning, P. J., Duffull, S. B., & Walker, R. J. (2011). Assessment of glycaemic control in chronic kidney disease. Nephrology, 16(Suppl. 1), (pp. 38). doi: 10.1111/j.1440-1797.2011.01493_7.x

Korell, J., Vos, F., Coulter, C., Schollum, J., Walker, R., & Duffull, S. (2011). Modelling red blood cell survival data. Proceedings of the Twentieth Annual Meeting of the Population Approach Group in Europe. PAGE. Retrieved from http://www.page-meeting.org/?abstract=2050

Korell, J., Vos, F., Sanhajariya, S., Coulter, C., Schollum, J., Walker, R., & Duffull, S. (2011). Modelling red blood cell data. Proceedings of the Population Approach Group in Australia and New Zealand Meeting (PAGANZ). PAGANZ. Retrieved from http://www.paganz.org/default.asp?id=45&keuze=program

Conference Contribution - Poster Presentation (not in published proceedings)

Eccles, M. R., Lett, B., Stayner, C., Wiles, A., Slobbe, L., Parker, K., Johnstone, A. C., Walker, R. J., … Markie, D. (2011, October). Genetic and phenotypic characterization of an ovine large animal model of the MKS/JBTS/NPHP ciliopathy, Meckel-Gruber syndrome. Poster session presented at the 12th International Congress of Human Genetics (ICHG) and 61st Annual Meeting of the American Society of Human Genetics (ASHG), Montreal, Canada.

Poole, C. A., Stayner, C., McGlashan, S. R., Parker, K., Wiles, A., Jennings, M., … Johnstone, A. C., Walker, R. J., & Eccles, M. R. (2011, June-July). Primary cilia defects in an ovine model of Meckel Gruber syndrome. Poster session presented at the FASEB Summer Research Conference: Polycystic Kidney Disease: From Bench to Bedside, Saxtons River, Vermont.

Wiles, A., Lett, B., Stayner, C., Slobbe, L., Markie, D., McEwan, J., Johnstone, A. C., Walker, R. J., Poole, C. A., & Eccles, M. (2011, June-July). A large animal ciliopathy: Genetic characterization of an ovine model of Meckel-Gruber syndrome. Poster session presented at the FASEB Summer Research Conference: Polycystic Kidney Disease: From Bench to Bedside, Saxtons River, Vermont.

Conference Contribution - Verbal presentation and other Conference outputs

Stayner, C., Lett, B., Slobbe, L., Wiles, A., Markie, D., McEwan, J., … Walker, R. J., Poole, C. A., & Eccles, M. (2011, September). Novel missense mutations in an ovine model of Meckel-Gruber Syndrome. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2010

Journal - Research Article

SHARP Collaborative Group, including Walker, R. (2010). Study of Heart and Renal Protection (SHARP): Randomized trial to access the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease. American Heart Journal, 160(5), 785-794 e10. doi: 10.1016/j.ahj.2010.08.012

Nejat, M., Pickering, J. W., Walker, R. J., Westhuyzen, J., Shaw, G. M., Frampton, C. M., & Endre, Z. H. (2010). Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit. Critical Care, 14(3), R85. doi: 10.1186/cc9014

Derrett, S., Darmody, M., Williams, S., Rutherford, M., Schollum, J., & Walker, R. (2010). Older peoples' satisfaction with home-based dialysis. Nephrology, 15(4), 464-470. doi: 10.1111/j.1440-1797.2010.01286.x

Nejat, M., Pickering, J. W., Walker, R. J., & Endre, Z. H. (2010). Rapid detection of acute kidney injury by plasma cystatin C in the intensive care unit. Nephrology Dialysis Transplantation, 25, 3283-3289. doi: 10.1093/ndt/gfq176

Todd, A. S., MacGinley, R. J., Schollum, J. B. W., Johnson, R. J., Williams, S. M., Sutherland, W. H. F., Mann, J. I., & Walker, R. J. (2010). Dietary salt loading impairs arterial vascular reactivity. American Journal of Clinical Nutrition, 91(3), 557-564. doi: 10.3945/ajcn.2009.28645

Endre, Z. H., Walker, R. J., Pickering, J. W., Shaw, G. M., Frampton, C. M., Henderson, S. J., Hutchison, R., … Robinson, J. M., Schollum, J. B. W., … Celi, L. A., … George, P. M. (2010). Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial). Kidney International, 77, 1020-1030. doi: 10.1038/ki.2010.25

Ting, Y. T., Coates, T. P., Marti, H. P., Dunn, A. C., Parker, R. M., Pickering, J. W., Jack, R. W., Kemp, R. A., Walker, R. J., & McLellan, A. D. (2010). Urinary soluble HLA-DR is a potential biomarker for acute renal transplant rejection. Transplantation, 89(9), 1071-1078. doi: 10.1097/TP.0b013e3181d15492

Journal - Research Other

Walker, R. (2010). The composition of peritoneal dialysis solutions: Tinkering or significant changes? [Commentary]. Peritoneal Dialysis International, 30(6), 600-601. doi: 10.3747/pdi.2010.00076

Conference Contribution - Published proceedings: Abstract

Endre, Z. H., Pickering, J. W., Walker, R. J., Devarajan, P., Edelstein, C. L., & Bonventre, J. V. (2010). Duration of injury and baseline renal function define biomarker performance in acute kidney injury. Journal of the American Society of Nephrology, 21, (pp. 3A). [Abstract]

Yoon, H.-S., Wilson, J. C., Walker, R. J., & Eccles, M. R. (2010). A novel CYS1638TYR NC1 domain substitution in α5 (IV) collagen causes Alport syndrome with late onset renal failure without hearing loss or eye abnormalities. Histopathology. 57(Suppl. 1), (pp. 237). doi: 10.1111/j.1365-2559.2010.03637.x

Conference Contribution - Poster Presentation (not in published proceedings)

Poole, T., McGlashan, S., Jensen, C., Eccles, M., Lett, B., Stayner, C., … Jennings, M., Wiles, A., & Walker, R. (2010, August-September). Primary cilia defects in an ovine model of Meckel-Gruber Syndrome. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Jennings, M., Poole, T., Walker, R., Mitchell, A., Easingwood, R., Harland, D., & Walls, R. (2010, August-September). An electron tomographic model of the Matrix-Cilium-Golgi Continuum in hyaline chondrocytes. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Poole, C. A., McGlashan, S. R., Jensen, C. G., Eccles, M. R., Lett, B., Stayner, C., Johnstone, A. C., Jennings, M., Wiles, A., & Walker, R. J. (2010, July). Primary cilia defects on an ovine model of Meckel-Gruber Syndrome. Poster session presented at the FASEB Summer Research Conference: The Biology of Cilia and Flagella, Saxtons River, Vermont.

Jennings, M., Poole, C. A., Walker, R. J., Mitchell, A., Easingwood, R., Harland, D., & Walls, R. (2010, July). An electron tomographic model of the Matrix - Cilium - Golgi Continuum in hyaline chondrocytes. Poster session presented at the FASEB Summer Research Conference: The Biology of Cilia and Flagella, Saxtons River, Vermont.

Conference Contribution - Verbal presentation and other Conference outputs

Eccles, M., Lett, B., Wiles, A., Jennings, M., Slobbe, L., Walker, R., Poole, A., & Stayner, C. (2010, August-September). A novel primary cilia phenotype characterizes an ovine polycystic kidney disease that maps to the Meckel syndrome gene, MKS3. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Walker, R., Bedford, J., Davis, G., Gobe, G., Schollum, J., & Leader, J. (2010, August-September). Long term lithium-induced chronic interstitial fibrosis. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Walker, R. (2010, November-December). Chronic fibrosis in kidney disease. Verbal presentation at the Medical Sciences Congress: A New Decade of Discovery (MedSciNZ), Queenstown, New Zealand.

Eccles, M., Lett, B., Wiles, A., Jennings, M., Slobbe, L., Poole, A., Stayner, C., & Walker, R. (2010, November-December). Primary cilia abnormalities characterize an ovine polycystic kidney disease that maps to the Meckel syndrome gene, MKS3. Verbal presentation at the Medical Sciences Congress: A New Decade of Discovery (MedSciNZ), Queenstown, New Zealand.

Davis, G., Bedford, J., Leader, J., & Walker, R. (2010, November-December). Lithium treated rats have an impaired ability to acidify their urine. Verbal presentation at the Medical Sciences Congress: A New Decade of Discovery (MedSciNZ), Queenstown, New Zealand.

Other Research Output

McCall, J., Walker, R. & McLellan, A. (2010, April). The immune system and organ transplantation. World Day of Immunology Public Lecture, Dunedin, New Zealand. [Public Seminar].

2009

Journal - Research Article

Bird, S. D., Walker, R. J., & Legge, M. (2009). L-Cysteine improves survival and growth of mesothelial cells after freezing. Cell Biology International, 33(11), 1155-1164. doi: 10.1016/j.cellbi.2009.08.003

Conference Contribution - Published proceedings: Abstract

Ting, Y., Coates, P. T., Marti, H., Dunn, A. C., Parker, R. M., Jack, R. W., Kemp, R. A., Walker, R. J., & McLellan, A. D. (2009). Urinary soluble HLA-DR is a potential biomarker for acute renal transplant rejection. Proceedings of the Australasian Society for Immunology 39th Annual Scientific Meeting. ASI. Retrieved from http://www.asi2009.org/

Vos, F. E., Manning, P. J., Sutherland, W. H. F., Schollum, J., & Walker, R. J. (2009). Does insulin have an anti-inflammatory effect in patients with end-stage renal disease on haemodialysis? Nephrology. 14(Suppl. 1), (pp. A4). [Abstract]

MacGinley, R. J., Todd, A. S., & Walker, R. J. (2009). Loss of endothelial plasticity as a mechanism for the salt sensitive patient with essential hypertension. International Journal of Cardiology, 137(Suppl. 1), (pp. S104-S105). doi: 10.1016/j.ijcard.2009.09.353

Conference Contribution - Poster Presentation (not in published proceedings)

Vos, F. E., Manning, P. J., Sutherland, W. H. F., Schollum, J., & Walker, R. J. (2009, September). Does insulin have an anti-inflammatory effect on haemodialysis in patients with end-stage renal disease? Poster session presented at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Ting, Y.-T., Walker, R., Coates, P. T., Dunn, A. C., Parker, R., Jack, R. W., … McLellan, A. D. (2009, June). Soluble HLA-DR: A potential urinary biomarker for renal transplant rejection. Verbal presentation at the New Zealand Australasian Society for Immunology (NZ ASI) Branch Meeting, Wellington, New Zealand.

2008

Chapter in Book - Research

Walker, R. J., & Endre, Z. H. (2008). Cellular mechanisms of drug nephrotoxicity. In R. J. Alpern & S. C. Hebert (Eds.), Seldin and Giebisch's: The kidney: Physiology and pathophysiology (Vols. 1-2). (4th ed.) (pp. 2507-2536). Burlington, MA: Academic Press.

Journal - Research Article

Manning, P. J., Sutherland, W. H. F., McGrath, M. M., de Jong, S. A., Walker, R. J., & Williams, M. J. A. (2008). Postprandial cytokine concentrations and meal composition in obese and lean women. Obesity, 16(9), 2046-2052. doi: 10.1038/oby.2008.334

Khan, E., Huggan, P., Celi, L., MacGinley, R., Schollum, J., & Walker, R. (2008). Sustained low-efficiency dialysis with filtration (SLEDD-f) in the management of acute sodium valproate intoxication. Hemodialysis International, 12(2), 211-214.

Bedford, J. J., Weggery, S., Ellis, G., McDonald, F. J., Joyce, P. R., Leader, J. P., & Walker, R. J. (2008). Lithium-induced nephrogenic diabetes insipidus: Renal effects of amiloride. Clinical Journal of the American Society of Nephrology, 3(5), 1324-1331.

Manning, P. J., Sutherland, W. H. F., Walker, R. J., Williams, S. M., de Jong, S. A., & Berry, E. A. (2008). The effect of rosiglitazone on oxidative stress and insulin resistance in overweight individuals. Diabetes Research & Clinical Practice, 81, 209-215.

Manning, P. J., Sutherland, W. H. F., Walker, R. J., de Jong, S. A., & Berry, E. A. (2008). The effect of glucose ingestion on inflammation and oxidative stress in obese individuals. Metabolism, 57, 1345-1349.

Merry, T. L., Ainslie, P. N., Walker, R., & Cotter, J. D. (2008). Fitness alters fluid regulatory but not behavioural responses to hypohydrated exercise. Physiology & Behavior, 95(3), 348-352.

Lucas, S. J. E., Anglem, N., Roberts, W. S., Anson, J. G., Palmer, C. D., Walker, R. J., … Cotter, J. D. (2008). Intensity and physiological strain of competitive ultra-endurance exercise in humans. Journal of Sports Sciences, 26(5), 477-489.

Bedford, J. J., Leader, J. P., Jing, R., Walker, L. J., Klein, J. D., Sands, J. M., & Walker, R. J. (2008). Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus. American Journal of Physiology: Renal Physiology, 294, F812-F820. doi: 10.1152/ajprenal.00554.2007

Zacharias, M., Conlon, N. P., Herbison, G. P., Sivalingam, P., Walker, R. J., & Hovhannisyan, K. (2008). Interventions for protecting renal function in the perioperative period (Review). Cochrane Database of Systematic Reviews, 4, CD003590. doi: 10.1002/14651858.CD003590.pub3

Conference Contribution - Published proceedings: Abstract

Manning, P. J., Sutherland, W. H. F., McGrath, M., de Jong, S. A., Walker, R. J., & Williams, M. J. A. (2008). The effect of meals rich in different types of fat and carbohydrate on plasma inflammatory cytokine concentrations in obese and lean women. Diabetes Research and Clinical Practice. 79(Suppl. 1), (pp. S16). [Abstract]

Winburn, I., Yao, Y., Hill, J., Endre, Z., Walker, R., & Sammut, I. (2008). Assessment of auto-regulation and endothelial function in kidneys undergoing hypothermic pulsatile perfusion. Transplantation. 86(Suppl. 2), (pp. 83-84). [Abstract]

Winburn, I., Yao, Y., Hill, J., Walker, R., Endre, Z., & Sammut, I. (2008). Renal auto-regulation and endothelial function during hypothermic pulsatile perfusion. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Annual Scientific Meeting. ASCEPT. Retrieved from http://phal.otago.ac.nz/ascept_docos/programme%202008.pdf

Todd, A., MacGinley, R., Schollum, J., Sutherland, W., Mann, J., & Walker, R. (2008). Sodium and hypertension: Is blood vessel function affected by dietary sodium intake? Journal of Hypertension, 26(Suppl. 1), (pp. S387). [Abstract]

Manning, P. J., Sutherland, W. H. F., Walker, R. J., de Jong, S. A., & Berry, E. A. (2008). The effect of glucose ingestion on inflammation and oxidative stress in obesity. Diabetes Research and Clinical Practice. 79(Suppl. 1), (pp. S26). [Abstract]

Conference Contribution - Poster Presentation (not in published proceedings)

Todd, A. S., MacGinley, R. J., Schollum, J. B. W., Sutherland, W. H. F., Mann, J. I., & Walker, R. J. (2008, August-September). Sodium and hypertension: Is blood vessel function affected by dietary sodium intake? Poster session presented at the Queenstown Molecular Biology Meetings, Queenstown, New Zealand.

Ting, Y.-T., Dunn, A. C., Parker, R., Jack, R. W., Berney-Meyer, L., Walker, R., & McLellan, A. D. (2008, August-September). Biochemical characterization of soluble HLA-DR: A potential urinary biomarker for renal transplant rejection. Poster session presented at the Queenstown Molecular Biology Meetings, Queenstown, New Zealand.

Winburn, I., Yao, Y., Hill, J., Walker, R., Endre, Z., & Sammut, I. (2008, August-September). Modulation of renal vascular function following administration of carbon monoxide during hypothermic pulsatile perfusion in a model of transplant ischaemia reperfusion injury. Poster session presented at the Queenstown Molecular Biology Meetings, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Winburn, I., Hill, J., Walker, R., Endre, Z., & Sammut, I. (2008, April). Renal vascular function during hypothermic pulsatile perfusion. Verbal presentation at the British Transplantation Society 11th Annual Congress, Glasgow, Scotland.

Walker, R. (2008, August-September). Lithium, aquaporins, and renal water handling. Verbal presentation at the Queenstown Molecular Biology Meetings, Queenstown, New Zealand.

2007

Journal - Research Article

Sutherland, W. H. F., Manning, P. J., Walker, R. J., de Jong, S. A., Ryalls, A. R., & Berry, E. A. (2007). Vitamin E supplementation and plasma 8-isoprostane and adiponectin in overweight subjects. Obesity, 15(2), 386-391. doi: 10.1038/oby.2007.546

Kerr, P. G., Sutherland, W. H. F., de Jong, S., Vaithalingham, I., Williams, S. M., & Walker, R. J. (2007). The impact of standard high-flux polysulfone versus novel high-flux polysulfone dialysis membranes on inflammatory markers: A randomized, single-blinded, controlled clinical trial. American Journal of Kidney Diseases, 49(4), 533-539. doi: 10.1053/j.ajkd.2006.12.019

Bradford, C. D., Cotter, J. D., Thorburn, M. S., Walker, R. J., & Gerrard, D. F. (2007). Exercise can be pyrogenic in humans. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 292, R143-R149. doi: 10.1152/ajpregu.00926.2005

Sutherland, W. H. F., de Jong, S. A., & Walker, R. J. (2007). Effect of dietary cholesterol and fat on cell cholesterol transfer to postprandial plasma in hyperlipidemic men. Lipids, 42, 901-911. doi: 10.1007/s11745-007-3101-1

Wilson, J. C., Yoon, H.-S., Walker, R. J., & Eccles, M. R. (2007). A novel Cys1638Tyr NC1 domain substitution in α5(IV) collagen causes Alport syndrome with late onset renal failure without hearing loss or eye abnormalities. Nephrology Dialysis Transplantation, 22(5), 1338-1346. doi: 10.1093/ndt/gfl793

Journal - Research Other

Connor, A., Highton, J., Hung, N. A., Dunbar, J., MacGinley, R., & Walker, R. (2007). Multicentric carpal-tarsal osteolysis with nephropathy treated successfully with cyclosporine A: A case report and literature review. American Journal of Kidney Diseases, 50(4), 649-654. doi: 10.1053/j.ajkd.2007.06.014

Conference Contribution - Published proceedings: Abstract

Endre, Z. H., Bennett, M., Celi, L., Dastrala, S., Devarajan, P., Dean, J., Frampton, C., Henderson, S., … Shaw, G., Walker, R., & Westhuyzen, J. (2007). Urinary gamma glutamyl transpeptidase-alkaline phosphatase indexed to urinary creatinine (GGT-AP) is correlated with urinary neutrophil gelatinase associated lipocalin (NGAL) on admission to Intensive Care. Journal of the American Society of Nephrology, 18, (pp. 576A). [Abstract]

2006

Journal - Research Article

Zoungas, S., McGrath, B. P., Branley, P., . . ., Walker, R., & McNeil, J. J. (2006). Cardiovascular morbidity and mortality in the Atherosclerosis and Folic Acid Supplementation Trial (ASFAST) in chronic renal failure. JACC, 47(6), 1108-1116.

Conference Contribution - Published proceedings: Abstract

Winburn, I. C., Harrison, J. C., MacGinley, R. J., Walker, R. J., & Sammut, I. A. (2006). Renal tubular damage following carbon monoxide releasing molecule exposure: Implications for future treatment of transplant ischaemia reperfusion injury. Transplantation. 82(Suppl. 3), (pp. 1043). [Abstract]

Leader, J., Jing, R., Walker, R., & Bedford, J. (2006). The effect of amiloride in lithium-induced nephrogenic diabetes insipidus in rats. FASEB Journal, 20(5), 754.17, (pp. A1222). [Abstract]

Bedford, J. J., Yang, B. S., Walker, R. J., & Leader, J. P. (2006). Upregulation of the taurine transporter, TAUT, in the renal medulla of thirsted rats. FASEB Journal, 20(5), 754.16, (pp. A1221). [Abstract]

Jing, R., Bedford, J., Walker, R., & Leader, J. (2006). Correction of the urine concentrating defect in rats with lithium-induced nephrogenic diabetes insipidus by amiloride. Journal of the American Society of Nephrology. 17, (pp. 537A). [Abstract]

2005

Journal - Research Article

Walker, R. (2005). Cardiovascular risk factors: Lipid-lowering therapy in patients with chronic kidney disease. Nephrology, 10, S231-S234.

Zacharias, M., Gilmore, I. C. S., Herbison, G. P., Sivalingam, P., & Walker, R. J. (2005). Interventions for protecting renal function in the perioperative period (Review). Cochrane Database of Systematic Reviews, 3. doi: 10.1002/14651858.CD003590.pub2

Thomas, M., Blennerhassett, J., & Walker, R. (2005). Relapse with transformation of lupus nephritis in a transplant kidney [Case report]. Lupus, 14, 554-556.

Sutherland, W. H. F., de Jong, S. A., & Walker, R. J. (2005). Hypochlorous acid and 3,4-dihydroxyphenylalanine increase the formation of serum protein lipofuscin-like fluorophores in vitro. Renal Failure, 27, 239-246.

Walker, R. J., Weggery, S., Bedford, J. J., McDonald, F. J., Ellis, G., & Leader, J. P. (2005). Lithium-induced reduction in urinary concentrating ability and urinary aquaporin 2 (AQP2) excretion in healthy volunteers. Kidney International, 67, 291-294.

Baker, J., Cotter, J. D., Gerrard, D. F., Bell, M. L., & Walker, R. J. (2005). Effects of indomethacin and celecoxib on renal function in athletes. Medicine & Science in Sports & Exercise, 37(5), 712-717.

Journal - Research Other

Manning, P. J., Sutherland, W. H. F., & Walker, R. J. (2005). Effect of high-dose vitamin E on insulin resistance and associated parameters in overweight subjects [Response to Vale]. Diabetes Care, 28(1), 230-231.

Haider, M., Gain, E., Khadem, G., Pilmore, H., Yun, K., Jayasinghe, J., & Walker, R. (2005). Simultaneous presentation of rofecoxib-induced acute hepatitis and acute interstitial nephritis [Letter to the editor]. Internal Medicine Journal, 35, 370-372.

Conference Contribution - Published proceedings: Abstract

Bedford, J. J., Jing, R., Walker, R. J., & Leader, J. P. (2005). The effect of amiloride on aquaporins 1-4 in rats with lithium-induced nephrogenic diabetes insipidus. Proceedings of the Cell Volume Control in Health and Disease Conference. (pp. 77). Copenhagen, Denmark. [Abstract]

Jing, Y., Bedford, J. J., Walker, R. J., & Leader, J. P. (2005). The effect of amiloride on lithium-induced nephrogenic diabetes insipidus in rats. Proceedings of the Medical Sciences Congress. (pp. 39). [Abstract]

Cotter, J. D., Lucas, S. J. E., Roberts, W. S., Walker, R. J., Palmer, C. D., & Rehrer, N. J. (2005). Altered fluid balance during 100 hours of exercise and sleep deprivation. Medicine & Science in Sports & Exercise, 37(Suppl. 5), (pp. S405). [Abstract]

Bradford, C. D., Walker, R. J., Gerrard, D. F., Thorburn, M., & Cotter, J. D. (2005). Is exercise pyrogenic? Medicine & Science in Sports & Exercise, 37(Suppl. 5), (pp. S129). [Abstract]

2004

Chapter in Book - Other

Kay, I. P., & Walker, R. J. (2004). Who should not go to the cathlab? In I. P. Kay, M. Sabaté & M. A. Costa (Eds.), Cardiac catheterization and percutaneous interventions. (pp. 1-7). London: Taylor & Francis Group.

Journal - Research Article

Palmer, S., Birks, C. L., Dunbar, J., & Walker, R. J. (2004). Simultaneous multiple tendon ruptures complicating a seizure in a haemodialysis patient. Nephrology, 9, 262-264.

Cooper, B. A., Branley, P., Bulfone, L., Collins, J. F., Craig, J. C., Dempster, J., … the IDEAL Study Steering Committee, including Walker, R. (2004). The Initiating Dialysis Early and Late (IDEAL) study: Study rationale and design. Peritoneal Dialysis International, 24(2), 176-181.

Manning, P. J., Sutherland, W. H., Walker, R. J., Williams, S. M., de Jong, S. A., Ryalls, A. R., & Berry, E. A. (2004). Effect of high-dose vitamin E on insulin resistance and associated parameters in overweight subjects. Diabetes Care, 27(9), 2166-2171.

McMahon, L. P., Roger, S. D., Levin, A., for the Slimheart Investigators Group, including Walker, R. J. (2004). Development, prevention, and potential reversal of left ventricular hypertrophy in chronic kidney disease. Journal of the American Society of Nephrology, 15, 1640-1647.

Roger, S. D., McMahon, L. P., Clarkson, A., Disney, A., Harris, D., Hawley, C., … Lynn, K., … Walker, R., & Levin, A. (2004). Effects of early and late intervention with epoetin α on left ventricular mass among patients with chronic kidney disease (stage 3 or 4): Results of a randomized clinical trial. Journal of the American Society of Nephrology, 15, 148-156.

Walker, R. J., Sutherland, W. H., & De Jong, S. A. (2004). Effect of changing from a cellulose acetate to a polysulphone dialysis membrane on protein oxidation and inflammation markers. Clinical Nephrology, 61(3), 198-206. doi: 10.5414/CNP61198

Tong, D. C., & Walker, R. J. (2004). Antibiotic prophylaxis in dialysis patients undergoing invasive dental treatment. Nephrology, 9, 167-170.

Sutherland, W. H. F., de Jong, S. A., & Walker, R. J. (2004). Hypochlorous acid and low serum paraoxonase activity in haemodialysis patients: An in vitro study. Nephrology Dialysis Transplantation, 19(1), 75-82.

Zoungas, S., Branley, P., Kerr, P. G., Ristevski, S., Muske, C., Demos, L., … Walker, R., … McGrath, B. P. (2004). Atherosclerosis and folic acid supplementation trial in chronic renal failure: Baseline results. Nephrology, 9, 130-141.

Bird, S. D., Legge, M., & Walker, R. J. (2004). Formaldehyde scavenging from peritoneal dialysis solutions using reduced aminothiol compounds. Nephrology, 9, 65-72.

Bird, S. D., Legge, M., & Walker, R. J. (2004). Cultured peritoneal mesothelial cells exhibit apical primary cilia. Cell Biology International, 28(2), 79-92.

Conference Contribution - Published proceedings: Abstract

Walker, R., Bedford, J., MacDonald, F., Weggery, S., & Leader, J. (2004). Lithium induced reducation of urinary aquaporin (AQP2) excretion and urinary concentrating ability in normal human volunteers. Proceedings of the 40th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology. (pp. A33). Adelaide, Australia: ANZSN. [Abstract]

Bradford, C., Walker, R., Gerrard, D., Thorburn, M., & Cotter, J. (2004). NSAIDS alter thermoregulation in exercise and recovery. New Zealand Sports Medicine & Science Conference. (pp. 52). Sports Medicine New Zealand. [Abstract]

2003

Journal - Research Article

Sutherland, W. H. F., Gieseg, S. P., Walker, R. J., de Jong, S. A., Firth, C. A., & Scott, N. (2003). Serum protein-bound 3,4-dihydroxyphenylalanine and related products of protein oxidation and chronic hemodialysis. Renal Failure, 25(6), 997-1009.

Bedford, J. J., Leader, J. P., & Walker, R. J. (2003). Aquaporin expression in normal human kidney and in renal disease. Journal of the American Society of Nephrology, 14, 2581-2587.

Al-Dameh, A. O., Bedford, J. J., Leader, J. P., & Walker, R. J. (2003). Urinary aquaporin-2 levels in healthy volunteers. Nephrology, 8, 139-141.

Delve, P., Lau, M., Yun, K., & Walker, R. (2003). Omeprazole-induced acute interstitial nephritis [Case report]. New Zealand Medical Journal, 116(1169). Retrieved from http://journal.nzma.org.nz/journal/116-1169/332/content.pdf

Bird, S. D., & Walker, R. J. (2003). Effects of bicarbonate buffered dialysate on human peritoneal mesothelial cell intracellular calcium homeostasis. Nephrology, 8, 150-155.

Conference Contribution - Published proceedings: Abstract

Walker, R. J., Bedford, J. J., & Leader, J. P. (2003). Lithium induced reducation of urinary aquaporin (AQP2) excretion and urinary concentrating ability in normal human volunteers. Journal of American Society of Nephrology. 14, (pp. 750A). [Abstract]

Bedford, J. J., Leader, J. P., & Walker, R. J. (2003). Glomerulart endothelium shows increased expression of AQP1 in renal disease. Proceedings of the Experimental Biology Late-Breaking. [Abstract]

Leader, J. P., Bedford, J. J., & Walker, R. J. (2003). Sidedness of expression of AQP1 in mIMCD cells. Proceedings of the Experimental Biology Late-Breaking. [Abstract]

2002

Journal - Research Article

Sutherland, W. H. F., de Jong, S. A., Walker, R. J., & Williams, S. M. (2002). Release of cholesterol from cell membranes to postprandial plasma from mildly hypercholesterolemic subjects: The effect of meals rich in olive and safflower oils. Metabolism, 51(10), 1306-1312.

Goodin, M. G., Walker, R. J., & Rosengren, R. J. (2002). Renal PGE2 production in the human and rat following phenactin, acetaminophen and p-aminophenol. Research Communications in Molecular Pathology & Pharmacology, 111, 153-166.

Lynn, K., & Walker, R. J. (2002). Darbepoetin alpha: A new erythropoietic drug for the treatment of renal anaemia. Nephrology, 7, S173-S180.

Yehia, M., McDonald, M. K., & Walker, R. J. (2002). The management and outcome of occluded haemodialysis access: A retrospective audit. New Zealand Medical Journal, 115(1166), U258. Retrieved from http://www.nzma.org.nz/journal/115-1166/258

Sutherland, W. H. F., De Jong, S. A., Walker, R. J., Williams, M. J. A., Skeaff, C. M., Duncan, A., & Harper, M. J. (2002). Effect of meals rich in heated olive and safflower oils on oxidation of postprandial serum in healthy men. Atherosclerosis, 160, 195-203.

Smiles, J., & Walker, R. J. (2002). A painful lower limb in a patient with a nephritic syndrome. Nephrology Dialysis Transplantation, 17, 295-296.

Sutherland, W. H. F., Walker, R. J., De Jong, S. A., & Williams, S. M. (2002). Release of cholesterol from cell membranes to postprandial plasma from mildly hypercholesterolemic subjects: the effect of meals rich in olive and safflower oils. Metabolism, 51(10), 1306-1312.

Conference Contribution - Published proceedings: Abstract

Walker, R. J., Bedford, J. J., & Leader, J. P. (2002). Aquaporin expression in renal disease. Journal of the American Society of Nephrology. 13, (pp. 472A). [Abstract]

2001

Journal - Research Article

Thomas, M. C., Russ, G. R., Mathew, T. H., Rao Mohan, M., Copper, J., & Walker, R. J. (2001). Four cases of CMV ureteritis: emergence of a new pattern of disease? Clinical Transplantation, 15, 354-358.

Walker, R. J., Dixon, S., Ruger, B. M., Davis, P. F., Hildebrant, F., Kremer, M., Eccles, M. R., McNoe, L. A., … Reid, J. J. (2001). Familial fibronectin glomerulopathy: Analysis of chromosome 1q32 and uteroglobulin gene loci in a large New Zealand family. Nephrology, 6, 191-197.

Williams, M. J. A., & Walker, R. J. (2001). When is an ANCA an anchor? Internal Medicine Journal, 31(5), 308-311.

Smiles, J., & Walker, R. J. (2001). Selective cyclo-oxygenase-2 inhibitor-induced oliguria: A postoperative complication. Internal Medicine Journal, 31, 497-498.

Walker, R. J., Lewis-Barned, N. J., Sutherland, W. H. F., Goulding, A., Edwards, E. A., de Jong, S. A., Gold, E. J., & Walker, H. (2001). The effects of sequential combined oral 17β-estradiol-Norethisterone acetate on insulin sensitivity and body composition in healthy postmenopausal women: A randomized single blind placebo-controlled study. Menopause, 8, 27-32.

McAuley, K. A., Williams, S. M., Mann, J., Walker, R. J., Lewis-Barned, N. J., Temple, L., & Duncan, A. (2001). Diagnosing insulin resistance in the general population. Diabetes Care, 24(3), 460-464.

Williams, M. J. A., Sutherland, W. H. F., McCormick, M., de Jong, S. A., McDonald, J. R., & Walker, R. J. (2001). Vitamin C improves endothelial dysfunction in renal allograft recipients. Nephrology Dialysis Transplantation, 16, 1251-1255.

Williams, M. J. A., Sutherland, W. H. F., McCormick, M., Yeoman, D., de Jong, S. A., & Walker, R. J. (2001). Normal endothelial function after meals rich in olive or safflower oil previously used for deep frying. Nutrition, Metabolism & Cardiovascular Diseases, 11, 147-152.

2000

Journal - Research Article

Lewis-Barned, N. J., Sutherland, W. H. F., Walker, R. J., de Jong, S. A., Walker, H. L., Edwards, E. A., Markham, V. H., & Goulding, A. (2000). Plasma cholesterol ester fatty acid composition, insulin sensitivity, the menopause and hormone replacement therapy. Journal of Endocrinology, 165, 649-655.

Goodin, M. G., Walker, R. J., & Rosengren, R. J. (2000). The effect of low doses of paracetamol on prostaglandin E2 production in the human and rat kidney. Australasian Journal of Ecotoxicology, 6(2), 85-88.

Conference Contribution - Published proceedings: Abstract

Goodin, M. G., Walker, R. J., & Rosengren, R. J. (2000). The effect of low concentrations of acetaminophen and ρ -aminophenol on PGE₂ production in the human and rat kidney. Toxicologist. 54, (pp. 402). London, UK: Oxford University Press. [Abstract]

Goodin, M. G., Walker, R. J., & Rosengren, R. J. (2000). Comparison between PGE₂ production in rat and human renal microsomes following exposure to phenacetin, paracetamol and ρ-aminophenol. The Otago Medical School Research Society. 78, (pp. 7). [Abstract]

Film/Video/CD Rom

Walker, R. J., & Wilkins, G. T. (2000). Cardiovascular risk factor assessment and management. Dunedin: Vidmark Productions. Retrieved from CD-ROM

1999

Authored Book - Research

Russell, D. G., Parnell, W. R., Wilson, N. C., Faed, J. M., Ferguson, E. L., Horwath, C. C., Herbison, G. P., Nye, E. R., Reid, P., Walker, R. J., Wilson, B. D., & Tukuitonga, C. (1999). NZ Food: NZ People. Key results of the 1997 National Nutrition Survey (LINZ® Activity & Health Research Unit). Wellington: Ministry of Health, 268p.

Journal - Research Article

Lewis-Barned, N. J., Sutherland, W. H. F., Walker, R. J., Walker, H. L., de Jong, S. A., Edwards, E. A., & Markham, V. H. (1999). Plasma cholesteryl esterification and transfer, the menopause and hormone replacement therapy in women. Journal of Clinical Endocrinology & Metabolism, 84, 3534-3538.

Walker, R. J., & International Collaborative Gp. (1999). Clinical and genetic heterogenity in familial focal segmental glomerulosclerosis. Kidney International, 55, 1241-1246.

Thomas, M. C., Walker, R. J., & Packer, S. G. (1999). Running repairs: renal artery dissection following extreme exertion. Nephrology Dialysis Transplantation, 14, 1258-1259.

Walker, R. J. (1999). Early start dialysis in diabetic nephropathy. Peritoneal Dialysis International, 19, S221-S223.

Thomas, M. C., Walker, R. J., & Wright, R. A. (1999). HaNDL syndrome after "benign" OKT3-induced meningitis. Transplantation, 67(10), 1384-1385.

Thomas, M. C., Walker, R. J., & Fisher, M. (1999). The simultaneous presentation of Goodpasture's disease and insulin dependent diabetes mellitus. Nephrology Dialysis Transplantation, 14, 1997-1998.

Sutherland, W. H. F., Walker, R. J., de Jong, S. A., & Upritchard, J. E. (1999). Supplementation with tomato juice increases plasma lycopene but does not alter susceptibility to oxidation of low density lipoproteins from renal transplant recipients. Clinical Nephrology, 52, 30-36.

Williams, M. J., Sutherland, W. H. F., McCormick, M. P., de Jong, S. A., Walker, R. J., & Wilkins, G. T. (1999). Impaired endothelial function after a meal rich in used cooking fat. JACC, 33, 1050-1055.

Thomas, M. C., Walker, R. J., & Hung, N. (1999). Tuberculosis: Still the great pretender. Hospital Medicine, 60, 214-215.

Walker, R. J., & International Collaborative Gp. (1999). Spectrum of disease in familial focal and segmental glomerulosclerosis. Kidney International, 165, 649-655.

Sutherland, W. H. F., Walker, R. J., de Jong, S. A., van Rij, A. M., Phillips, L. V., & Walker, H. (1999). Reduced postprandial serum paraoxonase activity after a meal rich in used cooking fat. Arteriosclerosis, Thrombosis, & Vascular Biology, 19, 1340-1347.

Journal - Professional & Other Non-Research Articles

Walker, R. J., & Manning, P. J. (1999). Diabetic nephropathy: Assessment and management. New Ethicals, 2(7), 49-55.

Conference Contribution - Published proceedings: Abstract

Goodin, M. G., Walker, R. J., & Rosengren, R. J. (1999). The effect of paracetamol, phenacetin and ρ-aminophenol on renal prostaglandin E₂ production in the rat. Proceedings of ASCEPT. 6, (pp. 41). Australian Society of Clinical and Experimental Pharmacologists and Toxicologists. [Abstract]

Film/Video/CD Rom

Walker, R. J., & Wilkins, G. T. (1999). Cardiovascular disease management. Dunedin: Vidmark Productions. Retrieved from CD-ROM

1998

Journal - Research Article

Bird, S. D., Hasan, Q., Davis, P. F., & Walker, R. J. (1998). Platelet-derived growth factor-BB induced calcium transients in cultured human peritoneal mesothelial cells. ASAIO Journal, 44, 835-840.

Bird, S. D. M., & Walker, R. J. (1998). Mast cell histamine-induced calcium transients in cultured human peritoneal mesothelial cells. Peritoneal Dialysis International, 18, 626-636.

Jones, G. T., van Rij, A. M., Packer, S. G., Walker, R. J., & Stehbens, W. E. (1998). Venous endothelial changes in therapeutic arteriovenous fistulae. Atherosclerosis, 137, 149-156.

Thomas, M. C., Bowie, D. R., & Walker, R. J. (1998). Acute barium toxicity following ceramic ingestion. Postgraduate Medical Journal, 545-546.

Bird, S. D., Hasan, Q., Davis, P. F., & Walker, R. J. (1998). Expression of platelet-derived growth factor and receptor mRNA in cultured human peritoneal mesothelial cells. ASAIO Journal, 44, 835-840.

Slaven, G. M., Fawcett, J. P., Walker, R. J., Hodgson, B. F., & Zacharias, M. (1998). Tenoxicam does not alter renal function during anaesthesia in normal individuals. Australian & New Zealand Journal of Medicine, 28(6), 772-776. doi: 10.1111/j.1445-5994.1998.tb01552.x

Thomas, M. C., Walker, R. J., & Yun, K. (1998). A norepinepherine secreting renal cell carcinoma: a case report. Nephrology Dialysis Transplantation, 13, 1811-1814.

Pilmore, H., Walker, R. J., McMillan, B. S., Paranjpe, D. V., & Berkeley, B. B. (1998). Acute bone pain following renal transplantation: differentiation between benign bone edema and avascular necrosis. American Journal of Nephrology, 18, 57-60.

Legge, M., Lash, G. E. E., Bird, S. D., & Walker, R. J. (1998). Formaldehyde in heat sterilised peritoneal dialysis solutions: scavenging system for its removal. Peritoneal Dialysis International, 18, 228-231.

Journal - Research Other

Thomas, M. C., Lyons, B. D., & Walker, R. J. (1998). John Thomas sign: Common distraction or useful pointer? Medical Journal of Australia, 169(11-12), 670. doi: 10.5694/j.1326-5377.1998.tb123461.x

1997

Chapter in Book - Research

Walker, R. J. (1997). Nephrology and urology. In The New Zealand Knowledge Base: a Report. (pp. 54-56). Wellington: Ministry of Research, Science and Technology.

Journal - Research Article

McAuley, K. A., Devereux, F., & Walker, R. J. (1997). Calciphylaxis in two non-compliant patients with end-stage renal failure. Nephrology Dialysis Transplantation, 12(5), 1061-1063.

Zhang, H., Coville, P., Walker, R. J., Miners, J. O., Birkett, D. J., & Wanwimolruk, S. (1997). Evidence for involvement of human CYP3A in the 3-hydroxylation of quinine. British Journal of Clinical Pharmacology, 43(3), 245-252.

Goulding, A., Gold, E. J., Walker, R. J., & Lewis-Barned, N. J. (1997). Women with past history of bone fracture have low spinal bone density before menopause. New Zealand Medical Journal, 110(1046), 232-233.

Walker, R. J. (1997). General management of end stage renal disease. British Medical Journal, 315(7120), 1429-1432.

Walker, R. J., Sutherland, W. H. F., Walker, H. L., MacMahon, S., & Robson, R. A. (1997). Effect of treatment with simvastatin on serum cholesteryl ester transfer in patients on dialysis. Nephrology Dialysis Transplantation, 12(1), 87-92. doi: 10.1093/ndt/12.1.87

Tillmann, H. C., Walker, R. J., Lewis-Barned, N. J., Edwards, E. A., & Robertson, M. C. (1997). A long-term comparison between enalapril and captopril on insulin sensitivity in normotensive non-insulin dependent diabetic volunteers. Journal of Clinical Pharmacy & Therapeutics, 22(4), 273-278.

Robson, R., Collins, J., Johnson, R., Kitching, R., Searle, M., Walker, R., … Whalley, G., … MacMahon, S. (1997). Effects of simvastatin and enalapril on serum lipoprotein concentrations and left ventricular mass in patients on dialysis. Journal of Nephrology, 10(1), 33-40.

Pilmore, H., Nagara, M. P., & Walker, R. J. (1997). Neurofibromatosis and renovascular hypertension presenting in early pregnancy. Nephrology Dialysis Transplantation, 12(1), 187-189.

Journal - Professional & Other Non-Research Articles

Thomas, M., & Walker, R. J. (1997). Renovascular hypertension. Primary Health Care New Zealand, (May), 24-30.

Conference Contribution - Published proceedings: Abstract

Bedford, J. J., Leader, J. P., & Walker, R. J. (1997). Glomerular endothelium shows increased expression of AQP1 in renal disease. Federation of American Soceities for Experimental Biology Journal. (pp. 17). [Abstract]

Bird, S. D., Hasan, Q., Davis, P. F., & Walker, R. J. (1997). Alternations in cultured human peritoneal mesothelial cell (HPMC) function in response to histamine and PDGF are calcium mediated. VIX International Congress of Nephrology. Sydney. [Abstract]

Walker, R. J., Dixon, S., Ruger, B. M., Davis, P. F., Eccles, M. R., & McNoe, L. A. (1997). Familial fibronectin nephropathy. 34th Australasian and New Zealand Society of Nephrology Conference. Auckland. [Abstract]

1996

Journal - Research Article

Bird, S. D., & Walker, R. J. (1996). Altered cellular biosynthesis in human peritoneal mesothelial cells exposed to dialysis solutions. Research Communications in Molecular Pathology & Pharmacology, 91, 319-328.

Rouse, J., Walker, R. J., & Packer, S. G. (1996). Inadvertent intravesical insertion of a Tenckhoff catheter. Peritoneal Dialysis International, 16, 218-219.

Bird, S. D., Legge, M., & Walker, R. J. (1996). L-Cysteine improves growth of human peritoneal mesothelial cells in vitro. Peritoneal Dialysis International, 16(6), 599-606.

Fawcett, J. P., Farquhar, S. J., Walker, R. J., Thou, T., Lowe, G., & Goulding, A. (1996). The effect of oral vanadyl sulfate on body composition and performance in weight-training athletes. International Journal of Sports Nutrition, 6(4), 382-390.

Fawcett, J. P., Schiller, B., Jiang, R., Walker, R. J., & Moran, J. (1996). Supplementation with L-oxothiazolidine-4-carboxylic acid, a cysteine precurser does not protect against lipid peroxidation in puromycin aminonucleoside-induced nephropathy. Experimental Nephrology, 4, 248-252.

1995

Journal - Research Article

Walker, R. J., Lewis-Barned, N. J., Edwards, E. A., & Robertson, M. C. (1995). The effects of increasing doses of enalapril on insulin sensitivity in normotensive non-insulin dependent diabetic subjects. Australian & New Zealand Journal of Medicine, 25, 698-702.

Oliver, S. E., Walker, R. J., & Woods, D. J. M. (1995). Fluconazole infused via a nephrostomy tube: a novel and effective route of delivery. Journal of Clinical Pharmacy & Therapeutics, 20, 317-318.

Wanwimolruk, S., Wong, S. M., Zhang, H., Coville, P., & Walker, R. J. (1995). Metabolism of quinine in man: identification fo a major metabolite, and effects of smoking and rifampicin pretreatment. Journal of Pharmacy & Pharmacology, 47, 957-963.

1994

Journal - Research Article

Walker, R. J., Fawcett, J. P., Flannery, E. M., & Gerrard, D. F. (1994). Indomethacin potentiates the exercise-induced reduction of renal haemodynamics in athletes. Medicine & Science in Sports & Exercise, 26(11), 1302-1306.