Contact Details
- Phone
- 64 3 479 5410
- shakila.rizwan@otago.ac.nz
University Links
- Position
- Senior Lecturer
- Qualifications
- BPharm PhD(Otago)
- Research summary
- Delivery of pharmceuticals to the brain
Research
My primary research interests are the development and evaluation (physicochemical and biological) of novel formulations for delivering pharmaceuticals to the brain. Specifically, I am interested in self-assembled liquid crystalline nanoparticles for targeted delivery of peptides/proteins to the brain.
- Development and validation of healthy and diseased (epilepsy) blood-brain barrier (BBB) models in the zebrafish.
- Understand factors affecting drug permeability/transport across the healthy and diseased (epilepsy) BBB.
- Formulation and physicochemical characterisation of self-assembled liquid crystalline nanoparticles (cubosomes and hexosomes).
- In vivo evaluation of formulations in rodent and zebrafish models.
Publications
Banstola, A., Vautrelle, N., Bergin, D., Gray, J., Murray, E., Mohammad, Y., Rizwan, S., … Tan, E., & Reynolds, J. (2023, June). Translational feasibility of a novel focused ultrasound approach for phasic dopamine receptor stimulation in a sheep model of Parkinson’s disease. Poster session presented at the International Basal Ganglia Society (IBAGS) XIV Meeting, Stockholm, Sweden. Conference Contribution - Poster Presentation (not in published proceedings)
Prentice, R. N., & Rizwan, S. B. (2023). Translational considerations in the development of intranasal treatments for epilepsy. Pharmaceutics, 15(1), 233. doi: 10.3390/pharmaceutics15010233 Journal - Research Article
Arora, S., Cooper, P., Friedlander, L., Rizwan, S., Seo, B., Rich, A., & Hussaini, H. (2022). Evaluation of IL-23 inhibitor as a pulp immunomodulating agent: An in vitro and in vivo study. New Zealand Dental Journal, 118(4), (pp. 167). [Abstract] Conference Contribution - Published proceedings: Abstract
Sarker, A., Horsfield, J., & Rizwan, S. (2022, November). Lipid nanoparticles reduce immune cell infiltration in a zebrafish model of brain inflammation. Verbal presentation at the School of Pharmacy Research Day, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Sarker, A., Horsfield, J., & Rizwan, S. (2022, November). Ednogenous lipid nanoparticles reduce immune cell infiltration in a zebrafish model of neuroinflammation. Verbal presentation at the New Zealand Controlled Release Society (NZCRS) Symposium, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
2023
Journal - Research Article
Prentice, R. N., & Rizwan, S. B. (2023). Translational considerations in the development of intranasal treatments for epilepsy. Pharmaceutics, 15(1), 233. doi: 10.3390/pharmaceutics15010233
Conference Contribution - Poster Presentation (not in published proceedings)
Banstola, A., Vautrelle, N., Bergin, D., Gray, J., Murray, E., Mohammad, Y., Rizwan, S., … Tan, E., & Reynolds, J. (2023, June). Translational feasibility of a novel focused ultrasound approach for phasic dopamine receptor stimulation in a sheep model of Parkinson’s disease. Poster session presented at the International Basal Ganglia Society (IBAGS) XIV Meeting, Stockholm, Sweden.
2022
Journal - Research Article
Arora, S., Cooper, P. R., Friedlander, L. T., Seo, B., Rizwan, S. B., Rich, A. M., & Hussaini, H. M. (2022). Potentiality and inflammatory marker expression are maintained in dental pulp cell cultures from carious teeth. International Journal of Molecular Sciences, 23(16), 9425. doi: 10.3390/ijms23169425
Prentice, R. N., Younus, M., & Rizwan, S. B. (2022). A sensitive LC-MS/MS method for quantification of phenytoin and its major metabolite with application to in vivo investigations of intravenous and intranasal phenytoin delivery. Journal of Separation Science, 45(14), 2529-2542. doi: 10.1002/jssc.202200025
Gandhi, K., Barzegar-Fallah, A., Banstola, A., Rizwan, S. B., & Reynolds, J. N. J. (2022). Ultrasound-mediated blood-brain barrier disruption for drug delivery: A systematic review of protocols, efficacy, and safety outcomes from preclinical and clinical studies. Pharmaceutics, 14, 833. doi: 10.3390/pharmaceutics14040833
Nakano, T., Rizwan, S. B., Myint, D. M. A., Gray, J., Mackay, S. M., Harris, P., Perk, C. G., Hyland, B. I., Empson, R., Tan, E. W., … Reynolds, J. N. J., & Wickens, J. R. (2022). An on-demand drug delivery system for control of epileptiform seizures. Pharmaceutics, 14, 468. doi: 10.3390/pharmaceutics14020468
Journal - Research Other
Barzegar-Fallah, A., Gandhi, K., Rizwan, S. B., Slatter, T. L., & Reynolds, J. N. J. (2022). Harnessing ultrasound for targeting drug delivery to the brain and breaching the blood–brain tumour barrier. Pharmaceutics, 14(10), 2231. doi: 10.3390/pharmaceutics14102231
Arora, S., Cooper, P. R., Ratnayake, J. T., Friedlander, L. T., Rizwan, S. B., Seo, B., & Hussaini, H. M. (2022). A critical review of in vitro research methodologies used to study mineralization in human dental pulp cell cultures. International Endodontic Journal, 55(Suppl. 1), 3-13. doi: 10.1111/iej.13684
Conference Contribution - Published proceedings: Abstract
Arora, S., Cooper, P., Friedlander, L., Rizwan, S., Seo, B., Rich, A., & Hussaini, H. (2022). Evaluation of IL-23 inhibitor as a pulp immunomodulating agent: An in vitro and in vivo study. New Zealand Dental Journal, 118(4), (pp. 167). [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Sarker, A., Horsfield, J., & Rizwan, S. (2022, November). Lipid nanoparticles reduce immune cell infiltration in a zebrafish model of brain inflammation. Verbal presentation at the School of Pharmacy Research Day, Dunedin, New Zealand.
Sarker, A., Horsfield, J., & Rizwan, S. (2022, November). Ednogenous lipid nanoparticles reduce immune cell infiltration in a zebrafish model of neuroinflammation. Verbal presentation at the New Zealand Controlled Release Society (NZCRS) Symposium, Auckland, New Zealand.
Sarker, A., Horsfield, J., & Rizwan, S. (2022, September). Lipid nanoparticles reduce immune cell infiltration and NF-κB activity in a zebrafish model of brain inflammation. Verbal presentation at the Postgraduate & Early Career Researchers Committee (PERC) & Division of Health Sciences Early & Mid-Career Researcher (EMCR) Joint Research Symposium, Dunedin, New Zealand.
2021
Journal - Research Article
Mohammad, Y., Prentice, R. N., Boyd, B. J., & Rizwan, S. B. (2021). Comparison of cubosomes and hexosomes for the delivery of phenytoin to the brain. Journal of Colloid & Interface Science, 605, 146-154. doi: 10.1016/j.jcis.2021.07.070
Prentice, R. N., Younus, M., Krittaphol-Bailey, W., & Rizwan, S. B. (2021). A sensitive LC-MS/MS method for the study of exogenously administered 13C-oleoylethanolamide in rat plasma and brain tissue. Journal of Separation Science, 44, 2693-2704. doi: 10.1002/jssc.202001210
Azhari, H., Younus, M., Hook, S. M., Boyd, B. J., & Rizwan, S. B. (2021). Cubosomes enhance drug permeability across the blood-brain barrier in zebrafish. International Journal of Pharmaceutics, 600, 120411. doi: 10.1016/j.ijpharm.2021.120411
Journal - Research Other
Arora, S., Cooper, P. R., Friedlander, L. T., Rizwan, S., Seo, B., Rich, A. M., & Hussaini, H. M. (2021). Potential application of immunotherapy for modulation of pulp inflammation: Opportunities for vital pulp treatment. International Endodontic Journal, 54, 1263-1274. doi: 10.1111/iej.13524
Conference Contribution - Published proceedings: Abstract
Goh, P. W. L., Gibson, B., & Rizwan, S. B. (2021). Oleoylethanolamide cubosomes exert potent anti-inflammatory effects on lipopolysaccharide-indcued dendritic cells and human brain endothelial cells. New Zealand Medical Journal, 134(1535), (pp. 97-98). Retrieved from https://www.nzma.org.nz/journal
2020
Journal - Research Article
Yarragudi, S. B., Kumar, H., Jain, R., Tawhai, M., & Rizwan, S. (2020). Olfactory targeting of microparticles through inhalation and bi-directional airflow: Effect of particle size and nasal anatomy. Journal of Aerosol Medicine & Pulmonary Drug Delivery, 33(5), 258-270. doi: 10.1089/jamp.2019.1549
Mohammad, Y., Barzegar Fallah, A., Reynolds, J. N. J., Boyd, B. J., & Rizwan, S. B. (2020). Steric stabilisers govern the colloidal and chemical stability but not in vitro cellular toxicity of linoleoylethanolamide cubosomes. Colloids & Surfaces B, 192, 111063. doi: 10.1016/j.colsurfb.2020.111063
Other Research Output
Rizwan, S. (2020, March). Getting medicines into the brain. Neurological Foundation of New Zealand Brain Awareness Month Otago Brain Day, Dunedin, New Zealand. [Public Seminar].
2019
Journal - Research Article
Yepuri, N. R., Clulow, A. J., Prentice, R. N., Gilbert, E. P., Hawley, A., Rizwan, S. B., … Darwish, T. A. (2019). Deuterated phytantriol: A versatile material for probing material distribution in liquid crystalline lipid phases using neutron scattering. Journal of Colloid & Interface Science, 534, 399-407. doi: 10.1016/j.jcis.2018.09.022
2018
Journal - Research Article
Younus, M., Hawley, A., Boyd, B. J., & Rizwan, S. B. (2018). Bulk and dispersed aqueous behaviour of an endogenous lipid, selachyl alcohol: Effect of Tween 80 and Pluronic F127 on nanostructure. Colloids & Surfaces B, 169, 135-142. doi: 10.1016/j.colsurfb.2018.05.013
2017
Journal - Research Article
Rizwan, S. B., & Vernall, A. J. (2017). To prohibit or regulate psychoactive substances: Has New Zealand got the right approach? BMJ, 356, j1195. doi: 10.1136/bmj.j1195
Yarragudi, S. B., Richter, R., Lee, H., Walker, G. F., Clarkson, A. N., Kumar, H., & Rizwan, S. B. (2017). Formulation of olfactory-targeted microparticles with tamarind seed polysaccharide to improve nose-to-brain transport of drugs. Carbohydrate Polymers, 163, 216-226. doi: 10.1016/j.carbpol.2017.01.044
Conference Contribution - Published proceedings: Abstract
Yarragudi, S. B., Barzegar-Fallah, A., Prentice, R. N., & Rizwan, S. B. (2017). Olfactory targeted mucoadhesive microparticles for enhanced brain uptake of phenytoin. Proceedings of the Australasian Pharmaceutical Science Association and the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (APSA-ASCEPT) Joint Scientific Meeting. (pp. 84). Retrieved from http://www.asceptasm.com/
2016
Journal - Research Article
Younus, M., Prentice, R. N., Clarkson, A. N., Boyd, B. J., & Rizwan, S. B. (2016). Incorporation of an endogenous neuromodulatory lipid, oleoylethanolamide, into cubosomes: Nanostructural characterization. Langmuir, 32(35), 8942-8950. doi: 10.1021/acs.langmuir.6b02395
Azhari, H., Strauss, M., Hook, S., Boyd, B. J., & Rizwan, S. B. (2016). Stabilising cubosomes with Tween 80 as a step towards targeting lipid nanocarriers to the blood-brain barrier. European Journal of Pharmaceutics & Biopharmaceutics, 104, 148-155. doi: 10.1016/j.ejpb.2016.05.001
Conference Contribution - Published proceedings: Abstract
Yarragudi, S. B., Lee, H., Richter, R., Kumar, H., & Rizwan, S. B. (2016). Formulation of olfactory-targeted microparticles of tamarind seed polysaccharide for nose-to-brain delivery of drug. Proceedings of the Drug Delivery Australia Conference. (pp. 77). Retrieved from http://www.crsaustralia.org/
Azhari, H., Hook, S., Boyd, B., & Rizwan, S. (2016). Formulation and uptake of cationic cubosomes in the zebrafish brain. Proceedings of the Drug Delivery Australia Conference. (pp. 70). Retrieved from http://www.crsaustralia.org/
Prentice, R., Burroughs, W., Mohammad, Y., & Rizwan, S. (2016). From SAXS to FACS: Investigating cellular interactions of phytantriol-oleoylethanolamide cubosomes. Proceedings of the Drug Delivery Australia Conference. (pp. 67). Retrieved from http://www.crsaustralia.org/
Younus, M., Clarkson, A. N., Boyd, B. J., & Rizwan, S. B. (2016). Investigating the effects of Tween 80 on sterically stabilising non-lamellar liquid crystalline nanoparticles of selachyl alcohol. Proceedings of the Drug Delivery Australia Conference. (pp. 57). Retrieved from http://www.crsaustralia.org/
Rizwan, S. (2016). Delivery of therapeutic molecules to the brain using particulate carriers. Proceedings of the Drug Delivery Australia Conference. (pp. 31). Retrieved from http://www.crsaustralia.org/
Rizwan, S., & Alsop, T.-A. (2016). Applied teaching verses foundation knowledge: How can we balance prior learning and applied teaching to ensure mathematically competent students in the health sciences? Proceedings of the First Year Biology Educators' Colloquium (FYBC). (pp. 7). Retrieved from http://www.otago.ac.nz/fybec/programme-and-speakers/index.html
Rizwan, S., & Alsop, T.-A. (2016). Contemplating strategies for teaching applied mathematics to diverse student cohort. Proceedings of the Tertiary Education Research in New Zealand (TERNZ) Conference. Retrieved from http://herdsa.org.nz/ternz/2016
Rizwan, S. B., Yarragudi, S. B., Richter, R., Walker, G. F., & Clarkson, A. N. (2016). Olfactory-targeted microparticles: A novel approach to bypass the blood-brain barrier. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 60). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
2015
Chapter in Book - Research
Rizwan, S. B., & Boyd, B. J. (2015). Cubosomes: Structure, preparation and use as an antigen delivery system. In C. Foged, T. Rades, Y. Perrie & S. Hook (Eds.), Subunit vaccine delivery. (pp. 125-140). New York: Springer. doi: 10.1007/978-1-4939-1417-3
Conference Contribution - Published proceedings: Abstract
Azhari, H., Tey, W. K., Hook, S., Boyd, B. J., & Rizwan, S. (2015). Interaction of cationic cubosomes with immortalized human brain endothelial cells. Proceedings of the Diagnostic Drug Device Discovery (D4) Conference. Retrieved from https://www.regonline.com.au/builder/site/Default.aspx?EventID=1758070
Younus, M., Clarkson, A. N., Boyd, B. J., & Rizwan, S. B. (2015). Structural stability of oleoylethanolamide, an endogenous neuromodulatory lipid is conserved when incorporated into cubosomes. Proceedings of the Diagnostic Drug Device Discovery (D4) Conference. Retrieved from https://www.regonline.com.au/builder/site/Default.aspx?EventID=1758070
Yarragudi, S. B., Ritcher, R., Walker, G. F., Clarkson, A. N., & Rizwan, S. B. (2015). Formulation of monodispursed mucoadhesive microparticles for nose-to-brain delivery. Proceedings of the Diagnostic Drug Device Discovery (D4) Conference. Retrieved from https://www.regonline.com.au/builder/site/Default.aspx?EventID=1758070
Azhari, H., Boyd, B., Hook, S., & Rizwan, S. (2015). Enhanced uptake of drug into the brain when delivered in BBB-targeted cubosomes. In B. Leitch (Ed.), Proceedings of the 33rd International Australasian Winter Conference on Brain Research. (pp. 46). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Mohammad, Y., Clarkson, A. N., Boyd, B. J., & Rizwan, S. B. (2015). Aqueous mixtures of phytantriol-oleoylethanolamide and pluronic F127 result in an intriguing variety of self-assembled lipid nanoparticles as revealed by Cryogenic Transmission Electron Microscopy (cryo-TEM). Proceedings of the 27th National Conference on Microscopy. Retrieved from http://microscopy2015.otago.ac.nz/index.html
Yarragudi, S. B., Walker, G. F., Clarkson, A. N., & Rizwan, S. B. (2015). Scanning electron microscopy as a tool to understand the effects of process variables on microparticle formation. Proceedings of the 27th National Conference on Microscopy. Retrieved from http://microscopy2015.otago.ac.nz/index.html
Azhari, H., Rizwan, S., Hook, S., Boyd, B. J., & Strauss, M. (2015). Modifying the surface of cubosomes with blood-brain barrier targeting ligands strongly influences its nanostructure. Proceedings of the 27th National Conference on Microscopy. Retrieved from http://microscopy2015.otago.ac.nz/index.html
Conference Contribution - Poster Presentation (not in published proceedings)
Azhari, H., Hook, S., Boyd, B. J., & Rizwan, S. B. (2015, July). Zebrafish can be used to determine permeability of nanoparticles across the blood-brain barrier in vivo. Poster session presented at the 11th International Conference on Cerebral Vascular Biology, Paris, France.
Conference Contribution - Verbal presentation and other Conference outputs
Rizwan, S. (2015, June). Nanoparticle technology for drug delivery to the brain. Verbal presentation at the 9th Annual Brain Health Research Centre Conference: Science for a Healthy Brain, Dunedin, New Zealand.
2014
Conference Contribution - Published proceedings: Abstract
Azhari, H., Boyd, B. J., & Rizwan, S. B. (2014). Influence of the surfactant Tween 80 on aqueous self-assembly of phytantriol. Proceedings of the 5th Pharmaceutical Sciences World Congress (PSWC). Retrieved from http://www.fip.org/pswc2014/Melbourne/2041/Programme/
Conference Contribution - Poster Presentation (not in published proceedings)
Rizwan, S., Azhari, H., Tey, W. K., & Boyd, B. (2014, November). Formulation and characterisation of catatonic cubosomes of phytantrial with cetrimonium bromide (CTAB) or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride (DOTAP). Poster session presented at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.
Yarragudi, S., Walker, G., Clarkson, A., & Rizwan, S. (2014, November). Formulation and characterisation of a novel microparticle system for nose-to-brain drug delivery. Poster session presented at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.
Mohammad, Y., Clarkson, A., Boyd, B., & Rizwan, S. (2014, November). Formulation and characterisation of phytantriol-oleoylethanolamide cubosomes. Poster session presented at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.
Azhari, H., Boyd, B. J., Strauss, M., & Rizwan, S. (2014, September). Influence of the surfactant Tween 80 on aqueous self-assembly of phytantriol. Poster session presented at the Division of Health Sciences Research Forum: Learning Different Research Languages, Dunedin, New Zealand.
2013
Journal - Research Article
Rizwan, S. B., McBurney, W. T., Young, K., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2013). Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses. Journal of Controlled Release, 165(1), 16-21. doi: 10.1016/j.jconrel.2012.10.020
Conference Contribution - Published proceedings: Abstract
Azhari, H., Boyd, B. J., & Rizwan, S. B. (2013). Phytantriol cubosomes sterically stabilised with the surfactants Tween 80 and Myrj 100: Formulation, characterisation and permeability studies in an in vitro model of the blood-brain barrier. Proceedings of the Australasian Pharmaceutical Science Association (APSA) Conference. Retrieved from http://apsa-online.org/home.html
Rizwan, S. (2013). Zebrafish as a vertebrate model: Opportunities in pharmaceutical research. Proceedings of the Australasian Pharmaceutical Science Association (APSA) Conference. Retrieved from http://apsa-online.org/home.html
2012
Journal - Research Article
Gordon, S., Young, K., Wilson, R., Rizwan, S., Kemp, R., Rades, T., & Hook, S. (2012). Chitosan hydrogels containing liposomes and cubosomes as particulate sustained release vaccine delivery systems. Journal of Liposome Research, 22(3), 193-204. doi: 10.3109/08982104.2011.637502
2011
Journal - Research Article
Rizwan, S. B., Assmus, D., Boehnke, A., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2011). Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines. European Journal of Pharmaceutics & Biopharmaceutics, 79(1), 15-22. doi: 10.1016/j.ejpb.2010.12.034
Kojarunchitt, T., Hook, S., Rizwan, S., Rades, T., & Baldursdottir, S. (2011). Development and characterisation of modified poloxamer 407 thermoresponsive depot systems containing cubosomes. International Journal of Pharmaceutics, 408(1-2), 20-26. doi: 10.1016/j.ijpharm.2011.01.037
Conference Contribution - Verbal presentation and other Conference outputs
Kojarunchitt, T., Baldursdottir, S., Rizwan, S., Rades, T., & Hook, S. (2011, February). In vivo investigation of modified P407 gels containing cubosomes as vaccine delivery system. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
2010
Journal - Research Article
Rizwan, S. B., Boyd, B. J., Rades, T., & Hook, S. (2010). Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins. Expert Opinion on Drug Delivery, 7(10), 1133-1144. doi: 10.1517/17425247.2010.515584
Conference Contribution - Published proceedings: Abstract
Kojarunchitt, T., Hook, S., Rizwan, S., Rades, T., & Baldursdottir, S. (2010). Development of sustained release vaccine delivery system containing modified poloxamer 407 loaded with cubosomes. Proceedings of the Globalization of Pharmaceutics Education Network (GPEN) 8th Biennial Meeting. (pp. 139). Retrieved from http://www.pharmacy.unc.edu/news/events/globalization-of-pharmaceutics-education-network-eighth-meeting-2010/program/GPEN2010_Program.pdf
2009
Journal - Research Article
Rizwan, S. B., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2009). Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: Characterisation, swelling and release kinetics. Journal of Pharmaceutical Sciences, 98(11), 4191-4204. doi: 10.1002/jps.21724
Conference Contribution - Published proceedings: Abstract
Hook, S., Myschik, J., Gordon, S., Rizwan, S., McBurney, W., & Rades, T. (2009). Designing sustained release, particulate, sub-unit vaccines. Proceedings of the Webster Centre for Infectious Diseases Symposium. WCID. Retrieved from http://www.webstercentre.otago.ac.nz/WCIDSymposiumProgramme.pdf
2008
Conference Contribution - Published proceedings: Full paper
Rizwan, S. B., McBurney, W., Boyd, B. J., Rades, T., & Hook, S. (2008). In vitro activity of phytantriol cubosomes containing the adjuvants imiquimod or monophosphoryl lipid A in bone marrow derived dendritic cells. Proceedings of the 35th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] St Paul, MN: CRS. [Full Paper]
Rizwan, S. B., Boyd, B. J., Rades, T., & Hook, S. (2008). Characterisation, swelling and release from liquid crystalline systems of phytantriol and glycerylmonooleate as platforms for controlled release of bioactives. Proceedings of the 35th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] St Paul, MN: CRS. [Full Paper]
Conference Contribution - Published proceedings: Abstract
Rizwan, S., McBurney, W., Boyd, B., Rades, T., & Hook, S. (2008). Enhanced type-1 immune response from a novel particulate vaccine delivery system comprised of phytantriol cubosomes containing toll-like receptor agonists imiquimod and or monophosphoryl lipid A. AAPS Journal, 10(S2). Retrieved from http://www.aapsj.org/abstracts/AM_2008/AAPS2008-001145.PDF
Conference Contribution - Verbal presentation and other Conference outputs
Rizwan, S. B., McBurney, W., Boyd, B. J., Rades, T., & Hook, S. (2008, November). In-vivo activity of a novel particulate vaccine delivery system comprised of phytantriol cubosomes containing toll-like receptor agonists imiquimod and monophosphoryl lipid A. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.
2007
Journal - Research Article
Rizwan, S. B., Dong, Y.-D., Boyd, B. J., Rades, T., & Hook, S. (2007). Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM). Micron, 38, 478-485. doi: 10.1016/j.micron.2006.08.003
Boyd, B. J., Rizwan, S. B., Dong, Y.-D., Hook, S., & Rades, T. (2007). Self-assembled geometric liquid-crystalline nanoparticles imaged in three dimensions: Hexosomes are not necessarily flat hexagonal prisms. Langmuir, 23(25), 12461-12464. doi: 10.1021/la7029714
Conference Contribution - Published proceedings: Full paper
Hook, S., Rizwan, S., Gordon, S., Saupe, A., & Rades, T. (2007). Towards the development of controlled release cancer vaccines. Proceedings of the 34th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]
Conference Contribution - Poster Presentation (not in published proceedings)
Rizwan, S., Assmus, D., Boyd, B., Rades, T., & Hook, S. (2007, November). Spontaneous formation of phytantriol based lyotropic liquid crystalline nanoparticles produced from liquid precursors. Poster session presented at the American Association of Pharmaceutical Scientists Annual Meeting and Exposition, San Diego, CA.
Rizwan, S., Dong, C., Boyd, B. J., Rades, T., & Hook, S. (2007, February). Characterising bicontinuous cubic nanoparticles by cryo field emission scanning electron microscopy. Poster session presented at the 9th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Rizwan, S., Assmus, D., Boyd, B. J., Rades, T., & Hook, S. (2007, February). Development and characterisation of phytantriol based lyotropic liquid crystalline nanoparticles produced via low viscosity precursors. Poster session presented at the 9th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
2006
Conference Contribution - Published proceedings: Abstract
Rizwan, S., Boyd, B., Hook, S., & Rades, T. (2006). Characterisation of bicontinuous cubic liquid crystalline phases by cryo FESEM. In P. Munroe (Ed.), Proceedings of the Australian Conference on Microscopy and Microanalysis. Melbourne, Australia: Australian Microscopy and Microanalysis Society Inc. Retrieved from www.acmm19.org.au
Conference Contribution - Poster Presentation (not in published proceedings)
Rizwan, S., Dong, C., Boyd, B., Hook, S., & Rades, T. (2006, May). Characterising bicontinuous cubic nanoparticles by cryo field emission scanning electron microscopy. Poster session presented at the Particles International Conference, Orlando, Florida.
2005
Conference Contribution - Published proceedings: Abstract
Rizwan, S. (2005). Lyotropic liquid crystalline nanoparticles for delivery of cancer vaccines. Proceedings of the ChemEd Conference. (pp. 14). [Abstract]