Associate Professor Peter Larsen

2024

Journal - Research Article

Jones, C., La Flamme, A., Larsen, P., & Hally, K. (2024). CPHEN-017: Comprehensive phenotyping of neutrophil extracellular traps (NETs) on peripheral human neutrophils [Phenotype report]. Cytometry Part A. Advance online publication. doi: 10.1002/cyto.a.24851

Flockton, A., Leong, A., Gilfillan, D., & Larsen, P. (2024). A multi-centre survey of New Zealand cancer patients' preferences for radiation treatment information. Journal of Medical Radiation Sciences, 71(1), 91-99. doi: 10.1002/jmrs.745

Hawkins, E., Stewart, B., Huggins, M., Compson, K., Larsen, P., & Rogan, A. (2024). What effect did the New Zealand COVID-19 lockdown have on computed tomography-head scan utilisation in patients presenting to the emergency department with traumatic head injuries? Emergency Medicine Australasia, 36, 94-100. doi: 10.1111/1742-6723.14322

2023

Journal - Research Article

Yiu, J. Y. T., Hally, K. E., Larsen, P. D., & Holley, A. S. (2023). Neutrophil-enriched biomarkers and long-term prognosis in acute coronary syndrome: A systematic review and meta-analysis. Journal of Cardiovascular Translational Research. Advance online publication. doi: 10.1007/s12265-023-10425-2

Bond, E. C., Whiting, F. H., Larsen, P. D., & Chan, G. (2023). A comparison of operative autonomy between men and women in orthopaedic surgical training in Aotearoa New Zealand. New Zealand Medical Journal/Te ara tika o te hauora hapori, 136(1579), 36-48. Retrieved from https://journal.nzma.org.nz/

Chadwick, K., Larsen, P., & Dungey, G. (2023). Planning experience of new graduate radiation therapists in New Zealand. Journal of Medical Radiation Sciences. Advance online publication. doi: 10.1002/jmrs.661

Sik, A., Kaveney-Gibb, B., Cooper, J., Pearson, J., Larsen, P., & Rogan, A. (2023). Is the Sport Concussion Assessment Tool 5th Edition a useful concussion assessment tool in head-injured patients presenting to the emergency department? Emergency Medicine Australasia, 35(3), 474-482. doi: 10.1111/1742-6723.14144

Rogan, A., Sik, A., Dickinson, E., Patel, V., Peckler, B., McQuade, D., Larsen, P. D., endorsed by ACEM Emergency Department Epidemiology Network. (2023). Diagnostic performance of S100B as a rule-out test for intracranial pathology in head-injured patients presenting to the emergency department who meet NICE Head Injury Guideline criteria for CT-head scan. Emergency Medicine Journal, 40, 159-166. doi: 10.1136/emermed-2022-212549

Yiu, J. Y. T., Hally, K. E., Larsen, P. D., & Holley, A. S. (2023). Increased levels of low density neutrophils (LDNs) in myocardial infarction. Acta Cardiologica, 78(1), 47-54. doi: 10.1080/00015385.2021.2015145

Journal - Research Other

McTavish, A., Larsen, P., Rogan, A., Carlin, E., Lynch, M., & Peckler, B. (2023). Exploring the feasibility of smartglass facilitated remote supervision in the emergency department: A simulation study [Short report]. Emergency Medicine Australasia, 35, 170-172. doi: 10.1111/1742-6723.14142

Conference Contribution - Published proceedings: Abstract

Mckee, G., Rutten, L., Larsen, P., & Leong, A. (2023). Feasibility and compliance of StrataXRT in treatment of radiation dermatitis in head and neck cancer. Radiotherapy & Oncology, 182(Suppl. 1), (pp. S976-S977). doi: 10.1016/S0167-8140(23)09217-4

O'Loughlin, E., Reid, D., Sims, S., & Larsen, P. (2023). The effect of menstrual cycle phase-based rehabilitation for women following anterior cruciate ligament reconstruction: A randomised controlled trial. Proceedings of the New Zealand Manipulative Physiotherapists Association (NZMPA) Biennial Conference. (pp. 30). Retrieved from https://www.nzmpa.org.nz

Holley, A., Yiu, J., Hally, K., & Larsen, P. (2023). Neutrophil biomarkers and long-term prognosis in acute coronary syndrome: A systematic review and meta-analysis. Heart, Lung & Circulation, 32(Suppl. 3), 678. doi: 10.1016/j.hlc.2023.06.582

Hummel, S., Hally, K., & Larsen, P. (2023). Activated platelets do not enhance Neutrophil Extracellular Trap (NET) formation. Heart, Lung & Circulation, 32(Suppl. 3), 662. doi: 10.1016/j.hlc.2023.06.563

Blackshaw, C., Hally, K., Harding, S., Fairley, S., Larsen, P., & Holley, A. (2023). Gender differences in demographics, management, and clinical outcomes in AMI patients. Heart, Lung & Circulation, 32(Suppl. 3), 386. doi: 10.1016/j.hlc.2023.06.382

Chadwick, K., Larsen, P., & Dungey, G. (2023). Planning experience of new graduate radiation therapists in New Zealand. Journal of Medical Radiation Sciences, 70(Suppl. 1), (pp. 8). doi: 10.1002/jmrs.664

Conference Contribution - Poster Presentation (not in published proceedings)

Helu, T., O'Loughlin, E., Paraneetharan, T., Larsen, P., & Popadich, A. (2023, April). Upper limb dysfunction and low physiotherapy referral rates in women following breast cancer treatment in Wellington. Poster session presented at the New Zealand Association of General Surgeons (NZAGS) Annual Scientific Meeting, Nelson, New Zealand.

2022

Journal - Research Article

Brunton-O'Sullivan, M. M., Holley, A. S., Shi, B., Harding, S. A., & Larsen, P. D. (2022). Cluster analysis of extracellular matrix biomarkers predicts the development of impaired systolic function within 1 year of acute myocardial infarction. Heart & Vessels, 37, 2029-2038. doi: 10.1007/s00380-022-02118-8

Brunton-O'Sullivan, M. M., Holley, A. S., Bird, G. K., Kristono, G. A., Harding, S. A., & Larsen, P. D. (2022). Examining variation and temporal dynamics of extracellular matrix biomarkers following acute myocardial infarction. Biomarkers in Medicine, 16(3), 147-161. doi: 10.2217/bmm-2021-0531

Rogan, A., Brunton-O'Sullivan, M., Holley, A., McQuade, D. d., & Larsen, P. (2022). Can serum biomarkers be used to rule out significant intracranial pathology in emergency department patients with mild traumatic brain injury? A systemic review & meta-analysis. Injury, 53, 259-271. doi: 10.1016/j.injury.2021.10.015

Rogan, A., Patel, V., Birdling, J., Lockett, J., Simmonds, H., McQuade, D., & Larsen, P. (2022). Acute traumatic brain injury and the use of head computed tomography scans in the emergency department. Trauma, 24(4), 327-336. doi: 10.1177/14604086211023646

Journal - Research Other

Hally, K. E., Ferrer-Font, L., Pilkington, K. R., & Larsen, P. D. (2022). OMIP 083: A 21-marker 18-color flow cytometry panel for in-depth phenotyping of human peripheral monocytes. Cytometry Part A, 101, 374-379. doi: 10.1002/cyto.a.24545

O'Hagan, L. A., Larsen, P. D., Natarajan, R. M., Pacilli, M., & Taghavi, K. (2022). Nomogram of paediatric male urethral size: A systematic review. Journal of Pediatric Urology, 18, 79-86. doi: 10.1016/j.jpurol.2021.10.014

Conference Contribution - Published proceedings: Abstract

Balfe, J., Rogan, A., & Larsen, P. (2022). Serum levels of S100B are significantly correlated with injury severity. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 81). Retrieved from https://www.queenstownresearchweek.org

Plant, A., Berry, J., Hooks, D., & Larsen, P. (2022). Antiarrhythmic use is associated with increased success and maintenance of sinus rhythm in patients undergoing first elective cardioversion. Heart, Lung & Circulation, 31(Suppl. 2), (pp. S32). doi: 10.1016/j.hlc.2022.05.029

Plant, A., Hooks, D., Larsen, P., & Berry, J. (2022). Predicting restoration and maintenance of sinus rhythm following first elective cardioversion for atrial fibrillation. Heart, Lung & Circulation, 31(Suppl. 2), (pp. S33). doi: 10.1016/j.hlc.2022.05.031

Plant, A., Hooks, D., Larsen, P., & Berry, J. (2022). Comparison of elective DC Cardioversion outcomes for first episode persistent atrial fibrillation/flutter between secondary and tertiary centres in New Zealand. Heart, Lung & Circulation, 31(Suppl. 2), (pp. S32-S33). doi: 10.1016/j.hlc.2022.05.030

Chambers, M., Garland, R., & Larsen, P. (2022). Lived experiences of deaf and hard of hearing young people in New Zealand. Proceedings of the New Zealand Society of Otolaryngology, Head & Neck Surgery (NZSOHNS) 74th Annual General & Scientific Meeting (ORL 21). Retrieved from https://www.orl2021.nz

2021

Journal - Research Article

Mouat, M., Gunawardene, A., Sweetman, L., Dennett, E., & Larsen, P. (2021). Psoas muscle cross-sectional area and outcomes following colorectal cancer surgery. British Journal of Surgical Science, 1(2), 39-45.

Gunawardene, A., Manning, S., Holley, A., Kristono, G., Danielson, K., Shekouh, A., Larsen, P., & Dennett, E. (2021). An IL8-CEA combined score is stage-specific in colorectal cancer. Surgery, Gastroenterology & Oncology, 26(4), 284-290. doi: 10.21614/sgo-26-4-401

Brunton-O'Sullivan, M. M., Holley, A. S., Hally, K. E., Kristono, G. A., Harding, S. A., & Larsen, P. D. (2021). A combined biomarker approach for characterising extracellular matrix profiles in acute myocardial infarction. Scientific Reports, 11, 12705. doi: 10.1038/s41598-021-92108-z

Hally, K. E., Parker, O. M., Brunton-O'Sullivan, M. M., Harding, S. A., & Larsen, P. D. (2021). Linking neutrophil extracellular traps and platelet activation: A composite biomarker for predicting outcomes after acute myocardial infarction. Thrombosis & Haemostasis, 121, 1637-1649. doi: 10.1055/s-0041-1728763

Marsters, B., Shi, B., Wheeler, B. J., Boucher, S., Macaulay, G., Galland, B., Elder, D., Larsen, P., & Wiltshire, E. (2021). Advanced ECG analysis of cardiac function in children and adolescents with type 1 diabetes: A pilot study. Acta Diabetologica, 58, 1119-1122. doi: 10.1007/s00592-021-01704-y

Rogan, A., Patel, V., Birdling, J., Lockett, J., Simmonds, H., McQuade, D., Quigley, P., & Larsen, P. (2021). Alcohol and acute traumatic brain injury in the emergency department. Emergency Medicine Australasia, 33, 718-727. doi: 10.1111/1742-6723.13726

Journal - Research Other

Cognasse, F., Hally, K., Fauteux-Daniel, S., Eyraud, M.-A., Arthaud, C.-A., Fagan, J., … Larsen, P. (2021). Effects and side effects of platelet transfusion. Hamostaseologie, 41, 128-135. doi: 10.1055/a-1347-6551

Conference Contribution - Published proceedings: Abstract

Kristono, G., Holley, A., Hally, K., Brunton-O'Sullivan, M., Shi, B., Harding, S., & Larsen, P. (2021). Using principal component analysis to create prognostic cytokine scores for adverse outcome in acute myocardial infarction. Heart, Lung & Circulation, 30(Suppl. 2), (pp. S57-S58). doi: 10.1016/j.hlc.2021.05.003

Russell, N., Black, M., Larsen, P., & Benton, M. (2021). Deep learning in a clinical context: The big picture from "big data". Proceedings of the eResearch NZ Conference. (pp. 103). Retrieved from https://www.eresearchnz2021.org.nz

2020

Journal - Research Article

Kristono, G. A., Holley, A. S., Hally, K. E., Brunton-O'Sullivan, M. M., Shi, B., Harding, S. A., & Larsen, P. D. (2020). An IL-6-IL-8 score derived from principal component analysis is predictive of adverse outcome in acute myocardial infarction. Cytokine: X, 2, 100037. doi: 10.1016/j.cytox.2020.100037

de Burlet, K. J., Desmond, B., Matsis, R., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2020). Reducing length of stay for patients presenting to general surgery with acute non-surgical abdominal pain. ANZ Journal of Surgery, 90, 2259-2263. doi: 10.1111/ans.16276

Ady Wirawan, I. M., Griffiths, R. F., & Larsen, P. D. (2020). Cardiovascular risk factor modification in asymptomatic adults and implications for pilots. Journal of UOEH, 42(2), 187-201. doi: 10.7888/juoeh.42.187

Kristono, G. A., Holley, A. S., Lakshman, P., Brunton-O'Sullivan, M. M., Harding, S. A., & Larsen, P. D. (2020). Association between inflammatory cytokines and long-term adverse outcomes in acute coronary syndromes: A systematic review. Heliyon, 6(4), e03704. doi: 10.1016/j.heliyon.2020.e03704

Kristono, G. A., Holley, A. S., Harding, S. A., & Larsen, P. D. (2020). White blood cell subtypes as predictors of adverse cardiac events. Coronary Artery Disease, 31(5), 446-450. doi: 10.1097/mca.0000000000000860

Kane, P., Larsen, P., & Wiltshire, E. (2020). Early identification of cardiac autonomic neuropathy using complexity analysis in children with type 1 diabetes. Journal of Paediatrics & Child Health, 56, 786-790. doi: 10.1111/jpc.14745

Foo, F. S., Lee, M., Looi, K.-L., Larsen, P., Clare, G. C., Heaven, D., … on behalf of the ANZACS-QI investigators. (2020). Implantable cardioverter defibrillator and cardiac resynchronization therapy use in New Zealand (ANZACS-QI 33). Journal of Arrhythmia, 36, 153-163. doi: 10.1002/joa3.12244

Hally, K. E., Holley, A. S., Kristono, G. A., Harding, S. A., & Larsen, P. D. (2020). Immunoglobulin G levels predicts risk of recurrent adverse cardiovascular events in myocardial infarction patients. Acta Cardiologica, 75(6), 497-502. doi: 10.1080/00015385.2019.1611189

Journal - Research Other

Hally, K., Fauteux-Daniel, S., Hamzeh-Cognasse, H., Larsen, P., & Cognasse, F. (2020). Revisiting platelets and Toll-like receptors (TLRs): At the interface of vascular immunity and thrombosis. International Journal of Molecular Sciences, 21(17), 6150. doi: 10.3390/ijms21176150

Gladding, P. A., Legget, M., Fatkin, D., Larsen, P., & Doughty, R. (2020). Polygenic risk scores in coronary artery disease and atrial fibrillation. Heart, Lung & Circulation, 29, 634-640. doi: 10.1016/j.hlc.2019.12.004

Conference Contribution - Published proceedings: Abstract

Kristono, G., Holley, A., Hally, K., Brunton-O'Sullivan, M., Harding, S., & Larsen, P. (2020). Trends in inflammatory cytokine levels over acute and chronic phases of myocardial infarction. Heart, Lung & Circulation, 29(Suppl. 2), (pp. S293). doi: 10.1016/j.hlc.2020.09.574

Brunton-O'Sullivan, M., Holley, A., Hally, K., Kristono, G., Bird, G., Harding, S., & Larsen, P. (2020). Examining the relationship between infarct size and circulating extracellular matrix biomarkers over acute and chronic phases of myocardial infarction. Heart, Lung & Circulation, 29(Suppl. 2), (pp. S257-S258). doi: 10.1016/j.hlc.2020.09.495

Yiu, J., Hally, K., Holley, A., & Larsen, P. (2020). Circulating low-density neutrophils in acute myocardial infarction. Heart, Lung & Circulation, 29(Suppl. 2), (pp. S242). doi: 10.1016/j.hlc.2020.09.464

Holley, A., Harding, S., & Larsen, P. (2020). An analysis on gender disparities in a contemporary acute myocardial infarction (AMI) cohort. Heart, Lung & Circulation, 29(Suppl. 2), (pp. S235). doi: 10.1016/j.hlc.2020.09.447

Fahmi, H., Laurie, A., Shepherd, P., Bhoothpur, C., Legget, M., Doughty, R., Holley, A., Larsen, P., & Gladding, P. (2020). Clinical applications of polygenic risk scores in coronary artery disease and familial hypercholesterolaemia. Heart, Lung & Circulation, 29(Suppl. 1), (pp. S5-S6). doi: 10.1016/j.hlc.2020.05.017

2019

Journal - Research Article

Hally, K. E., Bird, G. K., La Flamme, A. C., Harding, S. A., & Larsen, P. D. (2019). Platelets modulate multiple markers of neutrophil function in response to in vitro Toll-like receptor stimulation. PLoS ONE, 14(10), e0223444. doi: 10.1371/journal.pone.0223444

Foo, F. S., Lee, M., Heaven, D., Lever, N., Sinclair, S., Stiles, M. K., Harding, S., … Larsen, P., … on behalf of the ANZACS-QI investigators. (2019). Completeness of ANZACS-QI Cardiac Implanted DEVICE Registry and agreement with national datasets: ANZACS-QI 30. New Zealand Medical Journal, 132(1500), 40-49. Retrieved from https://www.nzma.org.nz/journal

de Burlet, K. J., Lam, A. B. M., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2019). Can surgical registrars accurately identify the urgent from the non-urgent patient presenting with acute abdominal pain? European Surgical Research, 60(1-2), 24-30. doi: 10.1159/000496021

Bond, E. C., Phillips, P., Larsen, P. D., Hunt, L., & Willoughby, R. (2019). Long-term hip function in slipped capital femoral epiphysis treated with in situ pinning. Journal of Orthopaedic Surgery, 27(1), 1-6. doi: 10.1177/2309499018822234

Tinawi, G., Gunawardene, A., Shekouh, A., Larsen, P. D., & Dennett, E. R. (2019). Neoadjuvant therapy in rectal cancer: How are we choosing? ANZ Journal of Surgery, 89, 68-73. doi: 10.1111/ans.14935

Hally, K. E., La Flamme, A. C., Harding, S. A., & Larsen, P. D. (2019). The effects of aspirin and ticagrelor on Toll-like receptor (TLR)-mediated platelet activation: Results of a randomized, cross-over trial. Platelets, 30(5), 599-607. doi: 10.1080/09537104.2018.1479520

Hancock, D. S., Sharplin, P. K., Larsen, P. D., & Phillips, F. T. S. (2019). Early radiological and functional outcomes for a cementless press-fit design modular femoral stem revision system. HIP International, 29(1), 35-40. doi: 10.1177/1120700018760277

Wilkins, B., Hullikunte, S., Simmonds, M., Sasse, A., Larsen, P., & Harding, S. A. (2019). Improving the prescribing gap for guideline recommended medications post myocardial infarction. Heart, Lung & Circulation, 28(2), 257-262. doi: 10.1016/j.hlc.2017.10.025

Journal - Research Other

Thunders, M., Holley, A., Harding, S., Stockwell, P., & Larsen, P. (2019). Using NGS-methylation profiling to understand the molecular pathogenesis of young MI patients who have subsequent cardiac events [Brief report]. Epigenetics, 14(6), 536-544. doi: 10.1080/15592294.2019.1605815

Gunawardene, A., Dennett, E., & Larsen, P. (2019). Prognostic value of multiple cytokine analysis in colorectal cancer: A systematic review. Journal of Gastrointestinal Oncology, 10(1), 134-143. doi: 10.21037/jgo.2018.07.11

Conference Contribution - Published proceedings: Abstract

Bellamy, F., De Burlet, K., Harper, S., Larsen, P., & Dennett, E. (2019). Discharges from general surgery with non-specific abdominal pain: Where do they end up? ANZ Journal of Surgery, 89(Suppl. 1), (pp. 70). doi: 10.1111/ans.15180

Tinawi, G., Gunawardene, A., Shekouh, A., Larsen, P., & Dennett, E. (2019). Neoadjuvant therapy in rectal cancer how are we choosing? ANZ Journal of Surgery, 89(Suppl. 1), (pp. 35). doi: 10.1111/ans.15180

Desmond, B., De Burlet, K., Harper, S. J., Larsen, P. D., & Dennett, L. R. (2019). Patients requiring an acute operation: Where are the delays in the process? ANZ Journal of Surgery, 89(Suppl. 1), (pp. 156). doi: 10.1111/ans.15180

Gunawardene, A., Larsen, P., & Dennett, E. (2019). Prognostic value of multiple cytokine analysis in colorectal cancer a systematic review. ANZ Journal of Surgery, 89(Suppl. 1), (pp. 37-38). doi: 10.1111/ans.15180

Gunawardene, A., Desmond, B., Shekouh, A., Larsen, P., & Dennett, L. (2019). Disease recurrence following surgery for colorectal cancer five-year follow up. ANZ Journal of Surgery, 89(Suppl. 1), (pp. 32). doi: 10.1111/ans.15180

Gunawardene, A., Manning, S., Danielson, K., Holley, A., Kristono, G., Shekouh, A., Larsen, P., & Dennett, E. (2019). A combined IL8 and CEA score is an effective marker of metastatic colorectal cancer. ANZ Journal of Surgery, 89(Suppl. 1), (pp. 23). doi: 10.1111/ans.15180

O'Connor, M., Carleton, O., Larsen, P., & Hooks, D. (2019). Does lead abandonment lead to increased risk of long term complications for patients with cardiac implantable electronic devices? Heart, Lung & Circulation, 28(Suppl. 1), (pp. S30). doi: 10.1016/j.hlc.2019.05.077

O'Connor, M., Carleton, O., Larsen, P., & Hooks, D. (2019). Does lead abandonment lead to increased risk of long-term complications for patients with CIEDs? Heart, Lung & Circulation, 28(Suppl. 4), (pp. S211). doi: 10.1016/j.hlc.2019.06.181

Kristono, G., Holley, A., Lakshman, P., Brunton-O'Sullivan, M., Harding, S., & Larsen, P. (2019). A systematic review of inflammatory cytokines as predictors of long-term outcome in acute coronary syndromes. Heart, Lung & Circulation, 28(Suppl. 1), (pp. S19). doi: 10.1016/j.hlc.2019.05.051

Bird, G., Hally, K., La Flamme, A., Harding, S., & Larsen, P. (2019). The role of B cells in acute myocardial infarction. Heart, Lung & Circulation, 28(Suppl. 1), (pp. S18). doi: 10.1016/j.hlc.2019.05.047

Brunton-O'Sullivan, M., Holley, A., Hally, K., Harding, S., & Larsen, P. (2019). An exploratory factor analysis of circulating extracellular matrix biomarkers in acute myocardial infarction. Heart, Lung & Circulation, 28(Suppl. 1), (pp. S14). doi: 10.1016/j.hlc.2019.05.039

Hally, K., La Flamme, A., Harding, S., & Larsen, P. (2019). Platelet toll-like receptor expression and toll-like receptor-mediated platelet responses in healthy and acute myocardial infarction subjects. Heart, Lung & Circulation, 28(Suppl. 1), (pp. S1-S2). doi: 10.1016/j.hlc.2019.05.007

Conference Contribution - Verbal presentation and other Conference outputs

Marsters, B., Larsen, P., Shi, B., Wheeler, B., Macaulay, G., Galland, B., Elder, D., & Wiltshire, E. (2019, September). Advanced ECG analysis of cardiac function in children with type 1 diabetes mellitus. Verbal presentation at the Australasian Pediatric Endocrine Group (APEG) Annual Scientific Meeting, Adelaide, Australia.

Allan, P. D., Saleem, S., O'Donnell, T., Fan, J.-L., Larsen, P. D., Berry, M. J., & Tzeng, Y.-C. (2019, September). New approaches to assessing and optimising cerebral perfusion. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2018

Journal - Research Article

Hancock, D. S., Rupasinghe, S. L., Elkinson, I., Bloomfield, M. G., & Larsen, P. D. (2018). Benzoyl peroxide + chlorhexidine versus chlorhexidine alone skin preparation to reduce Propionibacterium acnes: A randomized controlled trial. ANZ Journal of Surgery, 88, 1182-1186. doi: 10.1111/ans.14848

Hally, K. E., La Flamme, A. C., Harding, S. A., & Larsen, P. D. (2018). Platelets regulate leucocyte responses to Toll-like receptor stimulation. Clinical & Translational Immunology, 7, e1036. doi: 10.1002/cti2.1036

Gunawardene, A., Larsen, P., Shekouh, A., & Dennett, E. (2018). Pre-operative carcinoembryonic antigen predicts survival following colorectal cancer surgery with curative intent. ANZ Journal of Surgery, 88, 1311-1315. doi: 10.1111/ans.14723

de Burlet, K. J., Desmond, B., Harper, S. J., Larsen, P. D., & Dennett, E. R. (2018). Patients requiring an acute operation: Where are the delays in the process? ANZ Journal of Surgery, 88, 865-869. doi: 10.1111/ans.14718

Ady Wirawan, I. M., Griffiths, R. F., & Larsen, P. D. (2018). Cardiovascular tests for risk assessment in asymptomatic adults and implications for pilots. Aerospace Medicine & Human Performance, 89(7), 648-656. doi: 10.3357/amhp.5065.2018

de Burlet, K. J., MacKay, M., Larsen, P., & Dennett, E. R. (2018). Appropriateness of CT scans for patients with non-traumatic acute abdominal pain. British Journal of Radiology, 91(1088), 20180158. doi: 10.1259/bjr.20180158

O'Connor, M., Hooks, D., Webber, M., Shi, B., Morrison, S., Harding, S., & Larsen, P. (2018). Long-term single-center comparison of ICD lead survival: Evidence for premature Linox lead failure. Journal of Cardiovascular Electrophysiology, 29(7), 1024-1031. doi: 10.1111/jce.13502

Gunawardene, A., Desmond, B., Shekouh, A., Larsen, P., & Dennett, E. (2018). Disease recurrence following surgery for colorectal cancer: Five-year follow-up. New Zealand Medical Journal, 131(1469), 51-58. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Other

Hally, K. E., Danielson, K. M., & Larsen, P. D. (2018). Looking to the future: Spotlight on emerging biomarkers for predicting cardiovascular risk. Current Epidemiology Reports, 5, 230-242. doi: 10.1007/s40471-018-0158-8

de Burlet, K. J., Ing, A. J., Larsen, P. D., & Dennett, E. R. (2018). Systematic review of diagnostic pathways for patients presenting with acute abdominal pain. International Journal for Quality in Health Care, 30(9), 378-383. doi: 10.1093/intqhc/mzy079

Conference Contribution - Published proceedings: Full paper

de Burlet, K. J., Crane, G., Cullinane, R., Larsen, P. D., & Dennett, E. R. (2018). Review of appendicectomies over a decade in a tertiary hospital in New Zealand. ANZ Journal of Surgery, 88(12), (pp. 1253-1257). doi: 10.1111/ans.14203

Conference Contribution - Published proceedings: Abstract

Kristono, G., Holley, A., Sasse, A., Harding, S., & Larsen, P. (2018). Neutrophil-lymphocyte ratio as a prognostic marker in acute myocardial infarction. Heart, Lung & Circulation, 27(Suppl. 2), (pp. S332-S333). doi: 10.1016/j.hlc.2018.06.645

Hally, K., La Flamme, A., Harding, S., & Larsen, P. (2018). Neutrophil activation in response to Toll-like receptor stimulation is regulated by platelets. Heart, Lung & Circulation, 27(Suppl. 2), (pp. S332). doi: 10.1016/j.hlc.2018.06.644

O'Connor, M., Hooks, D., Webber, M., Shi, B., Morrison, S., Harding, S., & Larsen, P. (2018). Long-term single-centre comparison of implantable cardioverter-defibrillator lead survival: Evidence for premature linox lead failure. Heart, Lung & Circulation, 27(Suppl. 2), (pp. S58). doi: 10.1016/j.hlc.2018.06.034

Wilkins, B., Simmonds, M., Matsis, P., Scott, B., Gaskin, D., Harding, S., & Larsen, P. (2018). Effect of reduced frame-rate protocol on radiation dose during cardiac catheterisation. Heart, Lung & Circulation, 27(Suppl. 2), (pp. S491-S492). doi: 10.1016/j.hlc.2018.06.1021

Wilkins, B., Ranchord, A., Fairley, S., Larsen, P., & Harding, S. (2018). Estimation of coronary external elastic diameter from automated luminal measurements in optical coherence tomography. Heart, Lung & Circulation, 27(Suppl. 2), (pp. S492). doi: 10.1016/j.hlc.2018.06.1022

Kirby, A., Holley, A., Aitken, A., Larsen, P., & Harding, S. (2018). Family history of premature coronary artery disease: Accuracy and predictor of risk. Heart, Lung & Circulation, 27(Suppl. 1), (pp. S26). doi: 10.1016/j.hlc.2018.05.159

Gladding, P., Dugo, C., Wynne, Y., Semple, H., Smith, K., Shepherd, P., … Larsen, P., & Vilas-Boas, S. (2018). Screening for cardiac disease with genetic risk scoring, advanced ECG, echocardiography, protein biomarkers and metabolomics. Heart, Lung & Circulation, 27(Suppl. 1), (pp. S8). doi: 10.1016/j.hlc.2018.05.117

Conference Contribution - Verbal presentation and other Conference outputs

Bond, E., Philips, P., Hunt, L., Larsen, P., & Willoughby, R. (2018, October). Hip function in slipped capital femoral epiphysis treated with in situ pinning: Is there a correlation with slip severity? Verbal presentation at the New Zealand Orthopaedic Association (NZOA) Annual Scientific Meeting, Rotorua, New Zealand.

Hancock, D., Larsen, P., & Devane, P. (2018, October). Is early mobilisation the key to enhanced recovery after surgery for hip arthroplasty? Verbal presentation at the New Zealand Orthopaedic Association (NZOA) Annual Scientific Meeting, Rotorua, New Zealand.

2017

Journal - Research Article

Holley, A., Pitman, J., Miller, J., Harding, S., & Larsen, P. (2017). Glutathione peroxidase activity and expression levels are significantly increased in acute coronary syndromes. Journal of Investigative Medicine, 65(5), 919-925. doi: 10.1136/jim-2016-000361

de Burlet, K., Lam, A., Larsen, P., & Dennett, E. (2017). Acute abdominal pain: Changes in the way we assess it over a decade. New Zealand Medical Journal, 130(1463), 39-44. Retrieved from https://www.nzma.org.nz/journal

Harding, S. A., Holley, A., Wilkins, B., Fairley, S., Simmonds, M., & Larsen, P. D. (2017). Contemporary antiplatelet therapy in acute coronary syndromes: Are there differences in outcomes and discontinuation between clopidogrel and ticagrelor? Internal Medicine Journal, 47(11), 1298-1305. doi: 10.1111/imj.13595

Hally, K. E., La Flamme, A. C., Larsen, P. D., & Harding, S. A. (2017). Platelet Toll-like receptor (TLR) expression and TLR-mediated platelet activation in acute myocardial infarction. Thrombosis Research, 158, 8-15. doi: 10.1016/j.thromres.2017.07.031

Roberts, T., Campbell, A., Larsen, P., & Elder, D. (2017). Preterm infants at discharge: Nap polysomnography versus 24-hour oximetry. Acta Paediatrica, 106(111), 1754-1759. doi: 10.1111/apa.13900

Larsen, P. D., Holley, A. S., Sasse, A., Al-Sinan, A., Fairley, S., & Harding, S. A. (2017). Comparison of Multiplate and VerifyNow platelet function tests in predicting clinical outcome in patients with acute coronary syndromes. Thrombosis Research, 152, 14-19. doi: 10.1016/j.thromres.2017.02.006

Matsis, K., Holley, A., Al-Sinan, A., Matsis, P., Larsen, P. D., & Harding, S. A. (2017). Differing clinical characteristics between young and older patients presenting with myocardial infarction. Heart, Lung & Circulation, 26(6), 566-571. doi: 10.1016/j.hlc.2016.09.007

Larsen, P. D., Kerr, A. J., Hood, M., Harding, S. A., Hooks, D., Heaven, D., … on behalf of the ANZACS-QI Investigators. (2017). Pacemaker use in New Zealand: Data from the New Zealand Implanted Cardiac Device Registry (ANZACS-QI 15). Heart, Lung & Circulation, 26(3), 235-239. doi: 10.1016/j.hlc.2016.06.1206

Shi, B., Harding, S., & Larsen, P. (2017). Analysis of ECG measures of cardiac repolarization in relation to arrhythmic events in an implantable cardioverter defibrillator population. Annals of Noninvasive Electrocardiology, 22(2), e12390. doi: 10.1111/anec.12390

Journal - Research Other

Fake, A., Ranchord, A., Harding, S., & Larsen, P. (2017). Triple therapy versus dual antiplatelet therapy for patients with atrial fibrillation and acute coronary syndromes: A systematic literature review. Current Cardiology Reviews, 13(4), 325-333. doi: 10.2174/1573403x13666170927121808

Conference Contribution - Published proceedings: Abstract

de Burlet, K., MacKay, M., Larsen, P., & Dennett, E. (2017). Appropriateness of CT scans for patients with acute abdominal pain. ANZ Journal of Surgery, 87(Suppl. 1), (pp. 102). doi: 10.1111/ans.14003

de Burlet, K., Crane, G., Cullinane, R., Larsen, P., & Dennett, E. (2017). Negative appendicectomy rates over the last decade in a tertiary hospital in New Zealand. ANZ Journal of Surgery, 87(Suppl. 1), (pp. 54). doi: 10.1111/ans.13993

de Burlet, K., Dennett, E., Harper, S., Lam, A., & Larsen, P. (2017). How accurate is our early differentiation between the urgent and non-urgent patient presenting with acute abdominal pain? ANZ Journal of Surgery, 87(Suppl. 1), 45, (pp. 45). doi: 10.1111/ans.13993

Gunawardene, A., Larsen, P., & Dennett, E. (2017). Pre-treatment carcinoembryonic antigen predicts mortality following elective surgery for colorectal adenocarcinoma. ANZ Journal of Surgery, 87(Suppl. 1), (pp. 22). doi: 10.1111/ans.13990

Niu, C., Campbell, A., Larsen, P., & Elder, D. (2017). Intermittent hypoxia in preterm and term infants in the first year of life: Effects on growth and measures of heart rate variability. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 63-64). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html

Hally, K. E., La Flamme, A. C., Harding, S. A., & Larsen, P. D. (2017). Platelets modulate the leukocyte responses to Toll-like receptor stimulation. Proceedings of the 46th Australasian Society for Immunology (ASI) Annual Scientific Meeting. 242. Retrieved from http://www.asi2017.org/

Holley, A., Northcott, H., Gladding, P., Harding, S., & Larsen, P. (2017). Significant differences in genetic risk profiles between Maori and European presenting with myocardial infarction. Heart, Lung & Circulation, 26(Suppl. 2), (pp. S307-S308). doi: 10.1016/j.hlc.2017.06.612

Holley, A., Wilkins, B., Fairley, S., Ranchord, A., Larsen, P., & Harding, S. (2017). Prior myocardial infarction an independent predictor of adverse cardiovascular events. Heart, Lung & Circulation, 26(Suppl. 2), (pp. S91). doi: 10.1016/j.hlc.2017.06.110

Fake, A., Holley, A., Kirby, A., Sasse, A., Larsen, P., & Harding, S. (2017). Evaluating the ability of bleeding risk scores and platelet reactivity to predict bleeding risk in those presenting with myocardial infarction. Heart, Lung & Circulation, 26(Suppl. 2), (pp. S77). doi: 10.1016/j.hlc.2017.06.078

Harding, S., Holley, A., Fairley, S., Wilkins, B., Simmonds, M., & Larsen, P. (2017). Contemporary antiplatelet therapy in acute coronary syndromes: Are there differences in outcomes and complications between clopidogrel and ticagrelor? Heart, Lung & Circulation, 26(Suppl. 2), (pp. S292-S293). doi: 10.1016/j.hlc.2017.06.576

Lim, R. Y., Holley, A., Fairley, S., Sasse, A., Larsen, P., & Harding, S. (2017). Ticagrelor use and platelet reactivity in Maori and diabetic patients with acute coronary syndromes. Heart, Lung & Circulation, 26(Suppl. 1), (pp. S5). doi: 10.1016/j.hlc.2017.05.012

Wilkins, B., Matsis, P., Simmonds, M., Holley, A., Larsen, P., & Harding, S. (2017). Ticagrelor use and the “treatment risk paradox” in elderly patients with acute coronary syndromes. Heart, Lung & Circulation, 26(Suppl. 1), (pp. S7). doi: 10.1016/j.hlc.2017.05.018

O'Connor, M., Ranchord, A., Holley, A., Larsen, P., & Harding, S. (2017). What are the clinical and demographic characteristics of patients prescribed less than 12 months of Dual Anti-Platelet Therapy (DAPT) after an Acute Coronary Syndrome (ACS) event? Heart, Lung & Circulation, 26(Suppl. 1), (pp. S20). doi: 10.1016/j.hlc.2017.05.052

O'Connor, M., Matsis, P., Simmonds, M., Harding, S., Fairley, S., Ranchord, A., … Larsen, P., & Sasse, A. (2017). Aortic Stenosis Registry Wellington Hospital: Balloon Aortic Valvuloplasty (BAV) outcomes 2009-2016. Heart, Lung & Circulation, 26(Suppl. 1), (pp. S9-S10). doi: 10.1016/j.hlc.2017.05.025

Kirby, A., Aitken, A., Simmonds, M., Holley, A., Larsen, P., & Harding, S. (2017). Readmission rates 30 days following myocardial infarction. Heart, Lung & Circulation, 26(Suppl. 1), (pp. S17-S18). doi: 10.1016/j.hlc.2017.05.045

Wolbinski, M., Harding, S., & Larsen, P. (2017). Incidence and clinical characteristics of out of hospital cardiac arrest patients in the Wellington region. Internal Medicine Journal, 47(Suppl. 3), (pp. 9). doi: 10.1111/imj.7_13457

Conference Contribution - Verbal presentation and other Conference outputs

Hancock, D., Elkinson, I., Rupasinghe, S., Bloomfield, M., & Larsen, P. (2017, October). Benzoyl peroxide + chlorhexidine skin preparation vs chlorhexedine alone at the time of surgery for reduction of Propionibacterium acnes in the shoulder region: A randomized controlled trial. Verbal presentation at the New Zealand Orthopaedic Association (NZOA) Annual Scientific Meeting, Auckland, New Zealand.

2016

Journal - Research Article

Holley, A., Harding, S., Sasse, A., Miller, J., & Larsen, P. (2016). Reduced glutathione peroxidase activity predicts increased cardiovascular risk following an acute coronary syndrome. International Cardiovascular Forum Journal, 6, 61-65. doi: 10.17987/icfj.v6i0.241

Holley, A. S., Miller, J. H., Larsen, P. D., & Harding, S. A. (2016). Relationship between glutathione peroxidase, platelet reactivity, and reactive oxygen species in an acute coronary syndrome population. Annals of Clinical & Laboratory Science, 46(6), 639-644.

Hally, K. E., La Flamme, A. C., Larsen, P. D., & Harding, S. A. (2016). Toll-like receptor 9 expression and activation in acute coronary syndrome patients on dual anti-platelet therapy. Thrombosis Research, 148, 89-95. doi: 10.1016/j.thromres.2016.10.026

Nichol, G., Brown, S. P., Perkins, G. D., Kim, F., Sterz, F., Elrod, J. A. B., … Larsen, P., … Sayre, M. (2016). What change in outcomes after cardiac arrest is necessary to change practice? Results of an international survey. Resuscitation, 107, 115-120. doi: 10.1016/j.resuscitation.2016.08.004

Fake, A. L., Harding, S. A., Matsis, P. P., & Larsen, P. D. (2016). Pharmacological therapy following acute coronary syndromes in patients with atrial fibrillation: How do we balance ischaemic risk with bleeding risk? New Zealand Medical Journal, 129(1435), 39-49. Retrieved from https://www.nzma.org.nz/journal

Wolbinski, M., Swain, A. H., Harding, S. A., & Larsen, P. D. (2016). Out-of-hospital cardiac arrest patient characteristics: Comparing ventricular arrthymia and pulseless electrical activity. Heart, Lung & Circulation, 25(7), 639-644. doi: 10.1016/j.hlc.2016.02.001

Conference Contribution - Published proceedings: Abstract

Reddy, A., Dennett, E., & Larsen, P. (2016). Comparing the accuracy of biopsy via rigid endoscopy in clinic vs flexible endoscopy in the diagnosis of rectal adenocarcinoma. ANZ Journal of Surgery, 86(Suppl. 1), (pp. 31). doi: 10.1111/ans.13554

Wolbinski, M., Harding, S., & Larsen, P. (2016). Use of implantable cardioverter-defibrillators in survivors of ventricular fibrillation out of hospital cardiac arrest. Heart, Lung & Circulation, 25(Suppl. 2), (pp. S159). doi: 10.1016/j.hlc.2016.06.375

Holley, A., Al-Sinan, A., Fairley, S., Simmonds, M., Larsen, P., & Harding, S. (2016). Residual platelet reactivity measured by VerifyNow® is more predictive than Multiplate® of one year outcomes following acute coronary syndromes (ACS). Heart, Lung & Circulation, 25(Suppl. 2), (pp. S62). doi: 10.1016/j.hlc.2016.06.140

Hally, K., La Flamme, A., Larsen, P., & Harding, S. (2016). Platelet toll-like receptor (TLR)-9 expression increases in acute coronary syndrome (ACS) patients and following platelet activation. Heart, Lung & Circulation, 25(Suppl. 2), (pp. S56). doi: 10.1016/j.hlc.2016.06.127

Holley, A., Matsis, K., Northcott, H., Gladding, P., Harding, S., & Larsen, P. (2016). Genetic risk scoring in a young myocardial infarction (MI) population. Heart, Lung & Circulation, 25(Suppl. 2), (pp. S283-S284). doi: 10.1016/j.hlc.2016.06.664

Borrie, A., Matsis, P., Harding, S., Larsen, P., & Sasse, A. (2016). PFO closure in cryptogenic embolic events, Wellington Registry 2008-2016. Heart, Lung & Circulation, 25(Suppl. 1), (pp. S13). doi: 10.1016/j.hlc.2016.05.031

Fake, A., Larsen, P., & Harding, S. (2016). A systematic literature review examining antithrombotic therapy in Atrial Fibrillation (AF) patients with an Acute Coronary Syndrome (ACS). Heart, Lung & Circulation, 25(Suppl. 1), (pp. S14). doi: 10.1016/j.hlc.2016.05.034

2015

Journal - Research Article

Furniss, G., Shi, B., Jimenez, A., Harding, S. A., & Larsen, P. D. (2015). Cardiac troponin levels following implantable cardioverter defibrillation implantation and testing. Europace, 17(2), 262-266. doi: 10.1093/europace/euu306

Larsen, P. D., Johnston, L. R., Holley, A., La Flamme, A., Smyth, L., Chua, E. W., Kennedy, M. A., & Harding, S. A. (2015). Prevalence and significance of CYP2C19*2 and CYP2C19*17 alleles in a New Zealand acute coronary syndrome population. Internal Medicine Journal, 45(5), 537-545. doi: 10.1111/imj.12698

Webb, I. G., Yam, S. T., Cooke, R., Aitken, A., Larsen, P. D., & Harding, S. A. (2015). Elevated baseline cardiac troponin levels in the elderly: Another variable to consider? Heart, Lung & Circulation, 24(2), 142-148. doi: 10.1016/j.hlc.2014.07.071

Johnston, J. W., Larsen, P., El-Haddawi, F. H., Fancourt, M. W., Farrant, G. J., Gilkison, W. T. C., … Mosquera, D. A. (2015). Time delays in presentation and treatment of acute scrotal pain in a provincial hospital. ANZ Journal of Surgery, 85(5), 330-333. doi: 10.1111/ans.12601

Conference Contribution - Published proceedings: Abstract

Kane, P., Larsen, P., & Wiltshire, E. (2015). Early identification of cardiac autonomic neuropathy using compexity analysis. Proceedings of the International Society for Pediatric and Adolescent Diabetes + Australasian Paediatric Endocrine Group (ISPAD + APEG) Joint Annual Conference: Leaping the Barriers. O52. Retrieved from http://2015.ispad.org/jointispad-apeg2015/home

Holley, A., Miller, J., Harding, S., & Larsen, P. (2015). Characterisation of the glutathione peroxidase system in coronary artery disease. Heart, Lung & Circulation, 24(Suppl. 3), (pp. S140). doi: 10.1016/j.hlc.2015.06.064

Harding, S., Fairley, S., Al-Sinan, A., Holley, A., Howard, C., Matsis, P., Aitken, A., & Larsen, P. (2015). Bleeding, dyspnoea and discontinuation in a real world ACS cohort treated with ticagrelor. Heart, Lung & Circulation, 24(Suppl. 3), (pp. S376). doi: 10.1016/j.hlc.2015.06.615

Hally, K., La Flamme, A., Larsen, P., & Harding, S. (2015). Platelet activation by toll-like receptor (TLR)-9 agonism in acute coronary syndrome (ACS) patients on dual anti-platelet therapy. Heart, Lung & Circulation, 24(Suppl. 3), (pp. S159). doi: 10.1016/j.hlc.2015.06.112

Kane, P., Larsen, P., & Wiltshire, E. (2015). Early identification of cardiac autonomic neuropathy using complexity analysis. Proceedings of the American Diabetes Association (ADA) 75th Anniversary Scientific Sessions. ADA. Retrieved from http://professional.diabetes.org

Howard, C., Holley, A., Sasse, A., Harding, S., & Larsen, P. (2015). Is the incidence of high on treatment platelet reactivity (HOTPR) reduced in acute coronary syndrome (ACS) patients treated with ticagrelor? Heart, Lung & Circulation, 24(Suppl. 2), (pp. S100). doi: 10.1016/j.hlc.2015.04.126

Kampshof, L., Zhao, J., Larsen, P., & Nash, M. (2015). The effect of coronary occlusion on the regional electrophysiological function of the heart. Heart, Lung & Circulation, 24(Suppl. 2), (pp. S106). doi: 10.1016/j.hlc.2015.04.142

2014

Journal - Research Article

Ady Wirawan, I. M., Wu, R., Abernethy, M., Aldington, S., & Larsen, P. D. (2014). Calcium scores in the risk assessment of an asymptomatic population: Implications for airline pilots. Aviation, Space, & Environmental Medicine, 85(8), 812-817. doi: 10.3357/ASEM.3904.2014

Shi, B., Ferrier, K. A., Sasse, A., Harding, S. A., & Larsen, P. D. (2014). Correlation between vectorcardiographic measures and cardiac magnetic resonance imaging of the left ventricle in an implantable cardioverter defibrillator population. Journal of Electrocardiology, 47(1), 52-58. doi: 10.1016/j.jelectrocard.2013.06.018

Journal - Research Other

Lim, M. H., Smith, W., & Larsen, P. (2014). Is the benefit/risk ratio for cardiac defibrillators implanted in an older population (age 75 or more) still favourable? New Zealand Medical Journal, 127(1388). Retrieved from http://www.nzma.org.nz/journal

Conference Contribution - Published proceedings: Abstract

Wolbinski, M., Morgan, A., Larsen, P., & Sasse, A. (2014). 3D echo mitral valve reconstruction: Validity of a novel software application. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e48). doi: 10.1016/j.hlc.2014.04.251

Plunkett, S., Ranchord, A., Matsis, P., Holley, A., Larsen, P., & Harding, S. (2014). "Normal" coronary arteries in the setting of acute coronary syndromw: Frequency and outcomes. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e36-e37). doi: 10.1016/j.hlc.2014.04.222

Levings, S., Stiles, M., Heald, S., Jimenez, A., Shi, B., Harding, S., & Larsen, P. (2014). The effect of programming on therapy rates in implantable cardioverter defibrillator patients. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e16). doi: 10.1016/j.hlc.2014.04.167

Middleditch, D., Scott, B., Simmonds, M., Aitken, A., Johnston, L., Larsen, P., & Harding, S. (2014). Temporary and permanent discontinuation of clopidogrel following acute coronary syndromes. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e15-e16). doi: 10.1016/j.hlc.2014.04.166

Fairley, S., Harding, S., Liang, M., Aitken, A., Ranchord, A., & Larsen, P. (2014). Acute coronary syndromes in patients with prior MI: Secondary prevention and outcome. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e14-e15). doi: 10.1016/j.hlc.2014.04.163

Al-Sinan, A., Matsis, P., Simmonds, M., Johnston, L., Harding, S., & Larsen, P. (2014). The effects of ticagrelor on platelet reactivity and short term outcomes in acute coronary syndromes. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e16). doi: 10.1016/j.hlc.2014.04.160

Singh, K., Shi, B., Furniss, G., Jimenez, A., Blomfield, S., Harding, S., & Larsen, P. (2014). Factors contributing to failure to achieve a 10J safety margin in implantable cardioverter defibrillator testing. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e6). doi: 10.1016/j.hlc.2014.04.143

Bass, M., Chen-Xu, M., Sasse, A., La Flamme, A., Larsen, P., & Harding, S. (2014). Stimulation of platelet toll-like receptors results in marked platelet activation that is partially inhibited by prasugrel but not aspirin. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e4). doi: 10.1016/j.hlc.2014.04.136

Shi, B., Harding, S., & Larsen, P. (2014). Novel ECG derived risk markers in implantable cardioverter defibrillator (ICD) patients. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e4). doi: 10.1016/j.hlc.2014.04.137

Legge, C., Al-Sinan, A., Holley, A., Johnston, L., Larsen, P., & Harding, S. (2014). Does timing of platelet function testing (PFT) contribute to variability in residual on-treatment platelet reactivity in patients with acute coronary syndrome (ACS)? Heart, Lung & Circulation, 23(Suppl. 1), (pp. e31). doi: 10.1016/j.hlc.2014.04.205

Johnston, L., La Flamme, A., Larsen, P., & Harding, S. (2014). Prasugrel inhibits platelet stimulation of pro-inflammatory T cells in humans. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e3). doi: 10.1016/j.hlc.2014.04.135

Holley, A., Miller, J., Harding, S., & Larsen, P. (2014). Variability and prognostic significance of antioxidant enzymes in acute coronary syndromes (ACS). Heart, Lung & Circulation, 23(Suppl. 1), (pp. e27). doi: 10.1016/j.hlc.2014.04.196

Hally, K., Johnston, L., Holley, A., Larsen, P., & Harding, S. (2014). Platelet count and platelet function testing in acute coronary syndromes. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e26). doi: 10.1016/j.hlc.2014.04.192

Blomfield, S., Shi, B., Harding, S., & Larsen, P. (2014). Spatial QRS-T angle following acute coronary syndromes. Heart, Lung & Circulation, 23(Suppl. 1), (pp. e20). doi: 10.1016/j.hlc.2014.04.179

Conference Contribution - Verbal presentation and other Conference outputs

Larsen, P. (2014, November). Improving risk stratification for ventricular arrhythmia. Verbal presentation at the HeartOtago First Australasian Symposium: Bench to Bedside and Back: New Advances in Cardiovascular Research, Dunedin, New Zealand.

2013

Journal - Research Article

Ady Wirawan, I. M., Aldington, S., Griffiths, R. F., Ellis, C. J., & Larsen, P. D. (2013). Cardiovascular investigations of airline pilots with excessive cardiovascular risk. Aviation, Space, & Environmental Medicine, 84(6), 608-612. doi: 10.3357/ASEM.3465.2013

Fake, A. L., Swain, A. H., & Larsen, P. D. (2013). Survival from out-of-hospital cardiac arrest in Wellington in relation to socioeconomic status and arrest location. New Zealand Medical Journal, 126(1376). Retrieved from http://www.nzma.org.nz/journal

Harding, S. A., Shah, N., Briggs, N., Sasse, A., & Larsen, P. D. (2013). Complex transradial percutaneous coronary intervention using a sheathless guide catheter. Heart, Lung & Circulation, 22(3), 188-192. doi: 10.1016/j.hlc.2012.10.004

Johnston, L. R., Larsen, P. D., La Flamme, A. C., & Harding, S. A. (2013). Methodological considerations for the assessment of ADP induced platelet aggregation using the Multiplate® analyser. Platelets, 24(4), 303-307. doi: 10.3109/09537104.2012.694086

Tomkins, W. G. O., Swain, A. H., Bailey, M., & Larsen, P. D. (2013). Beyond the pre-shock pause: The effect of prehospital defibrillation mode on CPR interruptions and return of spontaneous circulation. Resuscitation, 84, 575-579. doi: 10.1016/j.resuscitation.2012.12.018

Shi, B., Harding, S. A., Jimenez, A., & Larsen, P. D. (2013). Standard 12-lead electrocardiography measures predictive of increased appropriate therapy in implantable cardioverter defibrillator recipients. Europace, 15(6), 892-898. doi: 10.1093/europace/eus360

Johnston, L. R., Larsen, P. D., La Flamme, A. C., Michel, J. M., Simmonds, M. B., & Harding, S. A. (2013). Suboptimal response to clopidogrel and the effect of prasugrel in acute coronary syndromes. International Journal of Cardiology, 167(3), 995-999. doi: 10.1016/j.ijcard.2012.03.080

Conference Contribution - Published proceedings: Abstract

Johnston, L., Harding, S., Scott, B., Larsen, P., & La Flamme, A. (2013). Antiplatelet therapy inhibits platelet regulation of CD4+ T cell differentiation in humans. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 83). Retrieved from http://www.asi2013.org/

Shi, B., Harding, S., Jimenez, A., & Larsen, P. (2013). Ventricular depolarisation variation in sinus and premature ventricular complexes (PVC). Heart, Lung & Circulation, 22(Suppl. 1), (pp. S103). doi: 10.1016/j.hlc.2013.05.244

Legge, C., Larsen, P., Mann, S., Harding, S., & Cooke, R. (2013). Strong independent relationship between renal impairment and high-sensitivity troponin levels. Heart, Lung & Circulation, 22(Suppl. 1), (pp. S226). doi: 10.1016/j.hlc.2013.05.536

Johnston, L., Scott, B., Wicks, K., Naik, D., Evans, R., La Flamme, A., Larsen, P., & Harding, S. (2013). An article on the predictive value of on treatment platelet reactivity in major vascular surgery patients. Heart, Lung & Circulation, 22(Suppl. 1), (pp. S11). doi: 10.1016/j.hlc.2013.05.023

Holley, A., Johnston, L., Harding, S., & Larsen, P. (2013). High levels of reactive oxygen species (ROS) are associated with reduced glutathione peroxidase (GPx) activity in acute coronary syndrome (ACS). Heart, Lung & Circulation, 22(Suppl. 1), (pp. S41). doi: 10.1016/j.hlc.2013.05.098

Woodcock, E., Harding, S., Shi, B., Lever, N., & Larsen, P. (2013). VF Frequency is influenced by cardiac structure. Heart, Lung & Circulation, 22(Suppl. 1), (pp. S103). doi: 10.1016/j.hlc.2013.05.245

Al-Sinan, A., Laing, M., Simmonds, M., Ranchord, A., Larsen, P., & Harding, S. (2013). Use of high sensitivity troponin T considerably increases the diagnosis of periprocedural myocardial infarction. Heart, Lung & Circulation, 22(7), (pp. 550). doi: 10.1016/j.hlc.2013.04.009

Mundell, D. J., Harding, S. A., & Larsen, P. D. (2013). Revascularisation, implantable cardioverter defibrillator use in patients surviving from out of hospital VF cardiac arrest. Heart, Lung & Circulation, 22(7), (pp. 571). doi: 10.1016/j.hlc.2013.04.056

Michel, J., Dickie, E., Eberhard, J., Leikis, M., Larsen, P., & Harding, S. (2013). Prevalence, severity and treatment of hypertension in patients receiving in-hospital haemodialysis. Heart, Lung & Circulation, 22(7), (pp. 571). doi: 10.1016/j.hlc.2013.04.055

Johnston, L., Smyth, L., Kennedy, M., Holley, A., Sasse, A., La Flamme, A., Larsen, P., & Harding, S. (2013). High on treatment platelet reactivity is associated with a higher risk of MACE in ACS patients: Diabetes and loss of function genotype the driving forces. Heart, Lung & Circulation, 22(7), (pp. 561). doi: 10.1016/j.hlc.2013.04.035

Holley, A. S., Johnston, L. R., Harding, S. A., & Larsen, P. D. (2013). Reduced glutathione peroxidase (GPx) activity in acute coronary syndrome (ACS) is correlated with high levels of reactive oxygen species (ROS). Heart, Lung & Circulation, 22(7), (pp. 560-561). doi: 10.1016/j.hlc.2013.04.033

Furniss, G., Shi, B., Jimenez, A., Harding, S., & Larsen, P. (2013). Factors affecting implantable cardioverter defibrillator (ICD) lifespan. Heart, Lung & Circulation, 22(7), (pp. 558). doi: 10.1016/j.hlc.2013.04.026

Donoghue, T., Larsen, P. D., Harding, S. A., & Aitken, A. (2013). Family history of sudden cardiac death: A comparison of medical records against detailed pedigrees. Heart, Lung & Circulation, 22(7), (pp. 555). doi: 10.1016/j.hlc.2013.04.020

Conference Contribution - Poster Presentation (not in published proceedings)

Holley, A. S., Johnston, L. R., Harding, S. A., & Larsen, P. D. (2013, August). Prognostic significance of antioxidant enzymes in acute coronary syndrome patients. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2012

Journal - Research Article

Hoyle, S., Swain, A. H., Fake, P., & Larsen, P. D. (2012). Introduction of an extended care paramedic model in New Zealand. Emergency Medicine Australasia, 24(6), 652-656. doi: 10.1111/j.1742-6723.2012.01608.x

Sykes, A. J., Larsen, P. D., Griffiths, R. F., & Aldington, S. (2012). A study of airline pilot morbidity. Aviation, Space, & Environmental Medicine, 83(10), 1001-1005. doi: 10.3357/asem.3380.2012

Wilson, D., Harding, S. A., Melton, I., Lever, N. A., Stiles, M. K., Boddington, D., Heald, S., & Larsen, P. D. (2012). Geographic, ethnic and socioeconomic factors influencing access to implantable cardioverter defibrillators (ICDs) in New Zealand. Heart, Lung & Circulation, 21(9), 576-581. doi: 10.1016/j.hlc.2012.04.012

Zaidi, M. A., Griffiths, R. F., Larsen, P. D., Newson-Smith, M., & Zaidi, M. A. (2012). The reporting of blood and body fluid exposure and follow-up practices in a tertiary care hospital in the United Arab Emirates. Ibnosina Journal of Medicine & Biomedical Sciences, 4(3), 84-89.

Myers, J. A., Psirides, A., Hathaway, K., & Larsen, P. D. (2012). Air transport by the Wellington Flight Service: A descriptive analysis of interhospital transfers over a 5-year period in the Wellington region of New Zealand. New Zealand Medical Journal, 125(1351). Retrieved from http://www.nzma.org.nz/journal

Swain, A. H., Al-Salami, M., Larsen, P. D., & Hoyle, S. R. (2012). Patient satisfaction and outcome using emergency care practitioners in New Zealand. Emergency Medicine Australasia, 24(2), 175-180. doi: 10.1111/j.1742-6723.2011.01525.x

Wirawan, I. M. A., Larsen, P. D., Aldington, S., Griffiths, R. F., & Ellis, C. J. (2012). Cardiovascular risk score and cardiovascular events among airline pilots: A case-control study. Aviation, Space, & Environmental Medicine, 83(5), 465-471. doi: 10.3357/ASEM.3222.2012

Elder, D. E., Larsen, P. D., Campbell, A. J., & Galletly, D. C. (2012). Cardioventilatory coupling and inter-breath variability in children referred for polysomnography. Respiratory Physiology & Neurobiology, 181(1), 1-7. doi: 10.1016/j.resp.2012.01.006

Conference Contribution - Published proceedings: Abstract

Roberts, T., Campbell, A., Larsen, P., & Elder, D. (2012). The effect of feed periods on 24-hour oximetry results of preterm neonates prior to discharge home. Journal of Paediatrics & Child Health, 48(Suppl. 1), (pp. 149). doi: 10.1111/j.1440-1754.2012.02412.x

Larsen, P. D., Harding, S. A., & Lever, N. A. (2012). Ventricular fibrillation recorded by implanted cardioverter defibrillators. Heart, Lung & Circulation, 21(12), (pp. 866). doi: 10.1016/j.hlc.2012.08.042

Larsen, P. D., Wilson, D., Harding, S. A., Melton, I., Lever, N. A., Boddington, D., … Stiles, M. K. (2012). Geographic, ethnic and socioeconomic factors influencing access to implantable-cardioverter defibrillators. Heart, Lung & Circulation, 21(8), (pp. 493). doi: 10.1016/j.hlc.2012.03.047

Webb, I., Yam, S., Cooke, R., Aitkin, A., Larsen, P., & Harding, S. (2012). Cardiac troponin levels in the elderly: Time to re-think threshold levels? Heart, Lung & Circulation, 21(Suppl. 1), (pp. S31). doi: 10.1016/j.hlc.2012.05.082

Webb, I., Simmonds, M., Larsen, P., & Harding, S. (2012). Low level troponin release in day-case PCI patients is common and does not preclude same-day discharge. Heart, Lung & Circulation, 21(Suppl. 1), (pp. S43). doi: 10.1016/j.hlc.2012.05.113

Johnston, L., Holley, A., Chen-Xu, M., Larsen, P., & Harding, S. (2012). Significant disagreement between the VerifyNow and Multiplate assays in the classification of high platelet reactivity on clopidogrel. Heart, Lung & Circulation, 21(Suppl. 1), (pp. S174-S175). doi: 10.1016/j.hlc.2012.05.434

Chen-Xu, M., Johnston, L., Holley, A., Sasse, A., Larsen, P. D., & Harding, S. A. (2012). Comparison of the Multiplate and VerifyNow assays for monitoring residual platelet reactivity after clopidogrel. Heart, Lung & Circulation, 21(8), (pp. 483-484). doi: 10.1016/j.hlc.2012.03.025

Woodcock, E. L., Lever, N. A., & Larsen, P. D. (2012). VF waveform complexity at ICD implant is predictive of future ICD therapy. Heart, Lung & Circulation, 21(8), (pp. 525). doi: 10.1016/j.hlc.2012.03.119

Woodcock, E. L., Lever, N. A., & Larsen, P. D. (2012). Ventricular fibrillation characteristics: What measurements are best? Heart, Lung & Circulation, 21(8), (pp. 525). doi: 10.1016/j.hlc.2012.03.120

Wirawan, I. M. A., Aldington, S., Griffiths, R. F., Ellis, C. J., & Larsen, P. D. (2012). Excessive cardiovascular risk and cardiac investigations in asymptomatic population: A study in airline pilots. Heart, Lung & Circulation, 21(8), (pp. 524). doi: 10.1016/j.hlc.2012.03.117

Webb, I. G., Yam, S. T., Cooke, R., Aitken, A., Larsen, P. D., & Harding, S. A. (2012). Elevated baseline cardiac troponin levels in the elderly: Another variable to consider? Heart, Lung & Circulation, 21(8), (pp. 520-521). doi: 10.1016/j.hlc.2012.03.110

Webb, I. G., Simmonds, M. B., Larsen, P. D., & Harding, S. A. (2012). Same-day discharge is safe in patients with low-level troponin elevation post-PCI. Heart, Lung & Circulation, 21(8), (pp. 520). doi: 10.1016/j.hlc.2012.03.109

Shi, B., Ferrier, K., Sasse, A., Harding, S. A., & Larsen, P. D. (2012). ECG markers of arrhythmogeneic substrate and structural heart disease. Heart, Lung & Circulation, 21(8), (pp. 514). doi: 10.1016/j.hlc.2012.03.095

Shah, N. M., Sasse, A. S., Matsis, P. P., Larsen, P. D., & Harding, S. A. (2012). Complex transradial percutaneous coronary intervention using a sheathless guide catheter. Heart, Lung & Circulation, 21(8), (pp. 514). doi: 10.1016/j.hlc.2012.03.094

Shah, N. M., Michel, J. M., Ashton, G., Psirides, A., Mahon, B. D., Larsen, P. D., & Sasse, A. S. (2012). Do cardiovascular risk factors predict complications in patients awaiting coronary artery bypass grafting. Heart, Lung & Circulation, 21(8), (pp. 513-514). doi: 10.1016/j.hlc.2012.03.093

Sasse, A. S., Michel, J. M., Shah, N. M., Ashton, G., Harding, S. A., Mahon, B. D., & Larsen, P. D. (2012). Validation study of Cardiac Clinical Prioritisation Score (CPS) for coronary artery bypass grafting. Heart, Lung & Circulation, 21(8), (pp. 513). doi: 10.1016/j.hlc.2012.03.092

Morgan, A. M., Webber, M., Harding, S., Scully, A., Sexton, J., Johnson, L., Larsen, P., & Sasse, A. (2012). Strain and pacing study: Role of pacing lead placement in LV contraction. Heart, Lung & Circulation, 21(8), (pp. 504-505). doi: 10.1016/j.hlc.2012.03.071

Millow, H. S., Webber, M. R., Larsen, P. D., Harding, S. A., Heald, S. C., & Stiles, M. K. (2012). Implantable Cardioverter Defibrillator registry in New Zealand: Initial experience. Heart, Lung & Circulation, 21(8), (pp. 521). doi: 10.1016/j.hlc.2012.03.111

Michel, J. M., Shah, N. M., Ashton, G., Psirides, A., Mahon, B. D., Larsen, P. D., & Sasse, A. (2012). New Zealand cardiac clinical prioritisation system: Left ventricular impairment predicts ICU length of stay after coronary artery bypass graft surgery. Heart, Lung & Circulation, 21(8), (pp. 503). doi: 10.1016/j.hlc.2012.03.068

McIntosh, R., Lou, P.-W., Shi, B., Harding, S. A., & Larsen, P. D. (2012). Predictors of mortality in the ICD population. Heart, Lung & Circulation, 21(8), (pp. 501). doi: 10.1016/j.hlc.2012.03.063

Larsen, P. D., Presant, L., & Harding, S. A. (2012). Estimating the need for implantable cardioverter defibrillators. Heart, Lung & Circulation, 21(8), (pp. 494). doi: 10.1016/j.hlc.2012.03.048

Johnston, L. R., La Flamme, A. C., Wicks, J. K., Naik, D., Larsen, P. D., & Harding, S. A. (2012). Variability in platelet reactivity and biomarkers in patients with peripheral vascular disease. Heart, Lung & Circulation, 21(8), (pp. 492). doi: 10.1016/j.hlc.2012.03.044

Holley, A. S., Johnston, L. R., Chen-Xu, M., Sasse, A., Larsen, P. D., & Harding, S. A. (2012). Plasma antioxidant enzyme levels in acute coronary syndrome. Heart, Lung & Circulation, 21(8), (pp. 490). doi: 10.1016/j.hlc.2012.03.040

2011

Journal - Research Article

Mahony, P. H., Myers, J. A., Larsen, P. D., Powell, D. M., & Griffiths, R. F. (2011). Symptom-based categorization of in-flight passenger medical incidents. Aviation, Space, & Environmental Medicine, 82(12), 1131-1137. doi: 10.3357/ASEM.3099.2011

Swain, A. H., Barry, T., Hoyle, S. R., Haywood, G., Cameron, H., & Larsen, P. D. (2011). Outcomes from out-of-hospital cardiac arrest in the Wellington region of New Zealand: Does use of the Fire Service make a difference? New Zealand Medical Journal, 124(1344). Retrieved from http://journal.nzma.org.nz/journal/124-1344/4913/content.pdf

Burgess, S. N., Harding, S. A., Melton, I. C., Lever, N. A., Swain, A. H., Shi, B., & Larsen, P. D. (2011). An unmet need for implantable cardioverter-defibrillators in New Zealand. Europace, 13(9), 1299-1303. doi: 10.1093/europace/eur113

Elder, D. E., Campbell, A. J., Larsen, P. D., & Galletly, D. (2011). Respiratory variability in preterm and term infants: Effect of sleep state, position and age. Respiratory Physiology & Neurobiology, 175(2), 234-238. doi: 10.1016/j.resp.2010.11.011

Journal - Research Other

Lever, N. A., & Larsen, P. D. (2011). Managing atrial fibrillation: The growing challenge [Editorial]. New Zealand Medical Journal, 124(1343). Retrieved from http://journal.nzma.org.nz/journal/124-1343/4886/content.pdf

Conference Contribution - Published proceedings: Abstract

Harding, S., Johnston, L., Michel, J., Ramanathan, A., La Flamme, A., Sasse, A., & Larsen, P. (2011). High on treatment platelet reactivity is common and differs among ethnic groups. Heart, Lung & Circulation, 20(Suppl. 2), (pp. S34-S35). doi: 10.1016/j.hlc.2011.05.088

Zhang, Z., O'Meeghan, T., Anscombe, R., Boga, T., Luo, D., Morgan, A., Harding, S., Larsen, P., & Sasse, A. (2011). Stress echocardiography: Quantification and identification of ischaemic wall motion through speckle-tracking. Heart, Lung & Circulation, 20(Suppl. 2), (pp. S191-S192). doi: 10.1016/j.hlc.2011.05.473

Wilson, D., Shi, B., Larsen, P. D., & Harding, S. A. (2011). Long term follow-up of implantable cardioverter defibrillator (ICD) patients in a single New Zealand centre. Heart, Lung & Circulation, 20(6), (pp. 416-417). doi: 10.1016/j.hlc.2011.03.106

Johnston, L. R., Michel, J., Ramanathan, A., La Flamme, A., Sasse, A., Larsen, P. D., & Harding, S. A. (2011). High on treatment platelet reactivity in a New Zealand ACS population. Heart, Lung & Circulation, 20(6), (pp. 389-390). doi: 10.1016/j.hlc.2011.03.043

Woodcock, E. L., Lever, N. A., & Larsen, P. D. (2011). Spectral analysis of 12 lead ECG recordings of ventricular fibrillation in humans. Heart, Lung & Circulation, 20(6), (pp. 417). doi: 10.1016/j.hlc.2011.03.107

Shi, B., Harding, S. A., & Larsen, P. D. (2011). ECG derived predictors of ventricular tachyarrhythmias in implantable cardioverter defibrillator patients. Heart, Lung & Circulation, 20(6), (pp. 408-409). doi: 10.1016/j.hlc.2011.03.087

Shah, N. M., Larsen, P. D., & Harding, S. A. (2011). Radial vs femoral arterial approach in rescue angioplasty: Wellington Regional Hospital experience. Heart, Lung & Circulation, 20(6), (pp. 407). doi: 10.1016/j.hlc.2011.03.084

Sasse, A. S., Mahon, B. D., Wignall, I., Burgess, S., Harding, S. A., & Larsen, P. D. (2011). Validation of the Cardiac Prioritisation Score for heart valve surgery. Heart, Lung & Circulation, 20(6), (pp. 407). doi: 10.1016/j.hlc.2011.03.083

Sasse, A. S., Lou, P. W., Morgan, A., Harding, S., Larsen, P., & Matsis, P. (2011). PFO closure in cryptogenic embolic events: Wellington Region Registry 2008-2011. Heart, Lung & Circulation, 20(6), (pp. 406-407). doi: 10.1016/j.hlc.2011.03.082

Lever, N., Conte, S., & Larsen, P. (2011). Clinical priority scores: Stratification for ablation procedures. Heart, Lung & Circulation, 20(6), (pp. 392-393). doi: 10.1016/j.hlc.2011.03.050

Conference Contribution - Verbal presentation and other Conference outputs

Roberts, T., Campbell, A., Larsen, P., & Elder, D. (2011, August). The effect of feed times on 24 hour oximetry prior to discharge home in preterm neonates. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Elder, D., Shi, B., Campbell, A., Galletly, D., & Larsen, P. (2011, July). Do convalescent preterm infants exhibit heart rate variability? Verbal presentation at the 38th Meeting of the Fetal and Neonatal Physiological Society (NPS), Palm Cove, Australia.

2010

Journal - Research Article

Robinson, S., Swain, A. H., Hoyle, S. R., & Larsen, P. D. (2010). Survival from out-of-hospital cardiac arrest in New Zealand following the 2005 resuscitation guideline changes. Resuscitation, 81(12), 1648-1651. doi: 10.1016/j.resuscitation.2010.07.009

Sin, P. Y. W., Webber, M. R., Galletly, D. C., Ainslie, P. N., Brown, S. J., Willie, C. K., Sasse, A., Larsen, P. D., & Tzeng, Y.-C. (2010). Interactions between heart rate variability and pulmonary gas exchange efficiency in humans. Experimental Physiology, 95(7), 788-797. doi: 10.1113/expphysiol.2010.052910

Elder, D. E., Larsen, P. D., Galletly, D. C., & Campbell, A. J. (2010). Cardioventilatory coupling in preterm and term infants: Effect of position and sleep state. Respiratory Physiology & Neurobiology, 174(1-2), 128-134. doi: 10.1016/j.resp.2010.05.012

Larsen, P. D., Tzeng, Y. C., Sin, P. Y. W., & Galletly, D. C. (2010). Respiratory sinus arrhythmia in conscious humans during spontaneous respiration. Respiratory Physiology & Neurobiology, 174(1-3), 111-118. doi: 10.1016/j.resp.2010.04.021

Marsland, C., Larsen, P., Segal, R., Hunter, S., Morris, J., Mezzavia, P., … Lim, W. (2010). Proficient manipulation of fibreoptic bronchoscope to carina by novices on first clinical attempt after specialized bench practice. British Journal of Anaesthesia, 104(3), 375-381. doi: 10.1093/bja/aeq005

Larsen, P. D., De Silva, P., Harding, S. A., Woodcock, E., & Lever, N. A. (2010). Use of implantable cardioverter defibrillators in the New Zealand context from 2000 to 2007. New Zealand Medical Journal, 123(1309). Retrieved from http://journal.nzma.org.nz/journal/123-1309/3977/content.pdf

Conference Contribution - Published proceedings: Abstract

Elder, D., Campbell, A., Larsen, P., & Galletly, D. (2010). Influences on respiratory variability in a paediatric clinical population. Sleep and Biological Rhythms. 8(Suppl. 1), (pp. A36). doi: 10.1111/j.1479-8425.2010.00457_4.x

Burgess, S., Harding, S., Melton, I., Lever, N. A., Swain, A., & Larsen, P. (2010). An unmet need for implantable cardioverter defibrillators in New Zealand. Heart, Lung & Circulation, 19(Suppl. 2), (pp. S210). doi: 10.1016/j.hlc.2010.06.507

Burgess, S. N., Harding, S. A., Melton, I., Lever, N. A., Swain, A. H., & Larsen, P. D. (2010). An unmet need for implantable cardioverter defibrillators in New Zealand. Heart, Lung & Circulation, 19(Suppl. 1), (pp. S5). doi: 10.1016/j.hlc.2010.04.009

Harding, S., Briggs, N., & Larsen, P. (2010). Complex radial percutaneous coronary intervention using the sheathless Eaucath. Heart, Lung & Circulation, 19(Suppl. 2), (pp. S126). doi: 10.1016/j.hlc.2010.06.962

Webber, M. R., Sin, P. Y., Ainslie, P. N., Tzeng, Y. C., Brown, S. J., Willie, C. K., Sasse, A. S., & Larsen, P. (2010). Heart rate variability and cardiorespiratory efficiency in humans. Heart, Lung & Circulation, 19(Suppl. 1), (pp. S34). doi: 10.1016/j.hlc.2010.04.073

Harding, S. A., Briggs, N., & Larsen, P. D. (2010). Complex radial percutaneous coronary intervention using the sheathless Eaucath. Heart, Lung & Circulation, 19(Suppl. 1), (pp. S14). doi: 10.1016/j.hlc.2010.04.029

Conference Contribution - Poster Presentation (not in published proceedings)

Sin, P., Webber, M., Galletly, D., Ainslie, P., Brown, S., Willie, C., Sasse, A., Larsen, P., & Tzeng, Y.-C. (2010, September). Interactions between heart rate variability and pulmonary gas exchange efficiency in humans. Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Sin, P. Y. W., Webber, M. R., Galletly, D. C., Ainslie, P. N., Brown, S. J., Willie, C. K., Sasse, A., Larsen, P. D., & Tzeng, Y.-C. (2010, November-December). Interactions between heart rate variability and pulmonary gas exchange efficiency in humans. Verbal presentation at the Medical Sciences Congress: A New Decade of Discovery (MedSciNZ), Queenstown, New Zealand.

Larsen, P. (2010, April-May). Compression ventilation ratio. Verbal presentation at the Resuscitation: On the Horizon Conference, Auckland, New Zealand.

2009

Journal - Research Article

Lever, N. A., Larsen, P. D., Dawes, M., Wong, A., & Harding, S. A. (2009). Are our medical graduates in New Zealand safe and accurate in ECG interpretation? New Zealand Medical Journal, 122(1292). Retrieved from http://journal.nzma.org.nz/journal/122-1292/3536/content.pdf

McHale, B., Harding, S. A., Larsen, P. D., & Lever, N. A. (2009). A national survey of clinician's knowledge of and attitudes towards implantable cardioverter defibrillators. Europace, 11(10), 1313-1316. doi: 10.1093/europace/eup236

Hermiz, S., Larsen, P., Galletly, D. C., & Harding, S. A. (2009). Peri-operative management of anti-platelet agents. ANZ Journal of Surgery, 79(7-8), 521-525. doi: 10.1111/j.1445-2197.2009.04981.x

Panfilov, I., Lever, N. A., Smaill, B. H., & Larsen, P. D. (2009). Ventricular fibrillation frequency from implanted cardioverter defibrillator devices. Europace, 11(8), 1052-1056. doi: 10.1093/europace/eup159

Conference Contribution - Published proceedings: Abstract

Elder, D. E., Campbell, A. J., Larsen, P., & Galletly, D. C. (2009). Breath-to-breath variability in term and preterm infants: When does a long respiratory pause become an apnoea? Journal of Paediatrics and Child Health. 45(Suppl. 1), (pp. A55). doi: 10.1111/j.1440-1754.2009.01474.x

Larsen, P., & Lever, N. (2009). Are failed ICD shocks due to changing ventricular fibrillation characteristics? Heart, Lung & Circulation, 18(Suppl. 2), (pp. S16). doi: 10.1016/j.hlc.2009.04.039

McHale, B., Harding, S., Lever, N., & Larsen, P. (2009). Barriers to ICD therapy: Clinicians perceptions are important. Heart, Lung & Circulation, 18(Suppl. 2), (pp. S23). doi: 10.1016/j.hlc.2009.04.054

Conference Contribution - Verbal presentation and other Conference outputs

Elder, D. E., Campbell, A. J., Larsen, P., & Galletly, D. C. (2009, October). What is an apnoea? Are you sure you know? Verbal presentation at the New Zealand Perinatal Society 29th Annual Scientific Meeting, Christchurch, New Zealand.

Elder, D. E., Campbell, A. J., Larsen, P. D., & Galletly, D. C. (2009, October). Cardioventilatry coupling in term and preterm infants. Verbal presentation at the New Zealand Perinatal Society 29th Annual Scientific Meeting, Christchurch, New Zealand.

2008

Journal - Research Article

Mahony, P. H., Griffiths, R. F., Larsen, P., & Powell, D. (2008). Retention of knowledge and skills in first aid and resuscitation by airline cabin crew. Resuscitation, 76, 413-418. doi: 10.1016/j.resuscitation.2007.08.017

Elder, D. E., Larsen, P., & Zuccollo, J. M. (2008). Failure of apnea monitoring during bed-sharing. Forensic Science, Medicine & Pathology, 4(3), 167-169. doi: 10.1007/s12024-008-9026-z

Conference Contribution - Published proceedings: Abstract

Elder, D., Campbell, A., Larsen, P., & Galletly, D. (2008). Cardioventilatory coupling in paediatric patients referred for polysomnography. Sleep and Biological Rhythms. 6(Suppl. 1), (pp. A21-A22). doi: 10.1111/j.1479-8425.2008.00359_3.x

Elder, D., Campbell, A., Larsen, P., & Galletly, D. (2008). Respiratory variability in term and preterm infants: Can we determine when a long respiratory pause becomes an apnoea? Sleep and Biological Rhythms. 6(Suppl. 1), (pp. A35-A36). doi: 10.1111/j.1479-8425.2008.00359_3.x

Conference Contribution - Verbal presentation and other Conference outputs

Elder, D. E., Campbell, A. J., Larsen, P. D., & Galletly, D. C. (2008, August). Respiratory variability in term and preterm infants: Can we determine when a long respiratory pause becomes an apnoea? Verbal presentation at the Perinatal Society Annual Scientific Meeting, Wellington, New Zealand.

2007

Journal - Research Article

Tzeng, Y. C., Larsen, P. D., & Galletly, D. C. (2007). Mechanism of cardioventilatory coupling: Insights from cardiac pacing, vagotomy, and sinoaortic denervation in the anesthetized rat. American Journal of Physiology: Heart & Circulatory Physiology, 292, H1967-H1977. doi: 10.1152/ajpheart.01049.2006

Lever, N. A., Newall, E. G., & Larsen, P. D. (2007). Differences in the characteristics of induced and spontaneous episodes of ventricular fibrillation. Europace, 9, 1054-1058.

Newall, E. G., Lever, N. A., Prasad, S., Hornabrook, C., & Larsen, P. D. (2007). Psychological implications of ICD implantation in a New Zealand population. Europace, 9, 20-24.

Parnell, M. M., & Larsen, P. D. (2007). Poor quality teaching in lay person CPR courses. Resuscitation, 73, 271-278.

Tzeng, Y. C., Larsen, P. D., & Galletly, D. C. (2007). Effects of hypercapnia and hypoxemia on respiratory sinus arrhythmia in conscious humans during spontaneous respiration. American Journal of Physiology: Heart & Circulatory Physiology, 292, H2397-H2407. doi: 10.1152/ajpheart.00817.2006

Conference Contribution - Published proceedings: Abstract

Elder, D. E., Campbell, A. J., Larsen, P. D., & Galletly, D. C. (2007). Respiratory cycle length in term infants: Influence of sleep position and sleep state. Journal of Paediatrics and Child Health. 43, (pp. A51-A52). [Abstract]

Conference Contribution - Verbal presentation and other Conference outputs

Elder, D. E., Campbell, A. J., Larsen, P. D., & Galletly, D. C. (2007, September). Respiratory cycle duration in term and preterm infants: Influence of sleep position and sleep state. Verbal presentation at the New Zealand Association of Neonatal Nurses and Perinatal Society of New Zealand Combined Conference, Auckland, New Zealand.

2006

Journal - Research Article

Parnell, M. M., Pearson, J., Galletly, D. C., & Larsen, P. D. (2006). Knowledge of and attitudes towards resuscitation in New Zealand high-school students. Emergency Medicine Journal, 23, 899-902.

Tanner, H., Larsen, P., Lever, N., & Galletly, D. (2006). Early recognition and early access for acute coronary syndromes in New Zealand: Key links in the chain of survival. New Zealand Medical Journal, 119(1232). Retrieved from http://journal.nzma.org.nz/journal/119-1232/1927/content.pdf

Journal - Research Other

Larsen, P. D., & Galletly, D. C. (2006). The sound of silence is music to the heart [Editorial]. Heart, 92(4), 433-434.

2005

Journal - Research Article

Tzeng, Y.-C., Galletly, D. C., & Larsen, P. D. (2005). Paradoxical respiratory sinus arrhythmia in the anesthetized rat. Autonomic Neuroscience, 118(1-2), 25-31.

Weller, J. M., Robinson, B. J., Jolly, B., Watterson, L. M., Joseph, M., Bajenov, S., … Larsen, P. D. (2005). Psychometric characteristics of simulation-based assessment in anaesthesia and accuracy of self-assessed scores. Anaesthesia, 60(3), 245-250.

O'Keeffe, K. M., Galletly, D. C., Miller, J. H., & Larsen, P. D. (2005). Quantal breathing frequency variation in halothane anaethetised neonatal rats. Respiratory Physiology & Neurobiology, 146(2-3), 147-153.

Williamson, L. J., Larsen, P. D., Tzeng, Y.-C., & Galletly, D. C. (2005). Effect of automatic external defibrillator audio prompts on cardiopulmonary resuscitation performance. Emergency Medicine Journal, 22(2), 140-143.

2004

Journal - Research Article

Weller, J., Robinson, B., Larsen, P., & Caldwell, C. (2004). Simulation-based training to improve acute care skills in medical undergraduates. New Zealand Medical Journal, 117(1204). Retrieved from http://journal.nzma.org.nz/journal/117-1204/1119/content.pdf

Galletly, D., Larsen, P., Lever, N., Aickin, R., & Smith, W. (2004). Energy settings for mono- and biphasic defibrillation: Guideline of the New Zealand Resuscitation Council [Review article]. New Zealand Medical Journal, 117(1193). Retrieved from http://journal.nzma.org.nz/journal/117-1193/875/content.pdf

McGuinness, M., Hong, Y., Galletly, D., & Larsen, P. (2004). Arnold tongues in human cardiorespiratory systems. Chaos, 14(1), 1-13.

Larsen, P., Pearson, J., & Galletly, D. (2004). Knowledge and attitudes towards cardiopulmonary resuscitation in the community. New Zealand Medical Journal, 117(1193). Retrieved from http://journal.nzma.org.nz/journal/117-1193/870/content.pdf

Larsen, P. D., Elder, D. E., Tzeng, Y.-C., Campbell, A., & Galletly, D. C. (2004). Fractal characteristics of breath to breath timing in sleeping infants. Respiratory Physiology & Neurobiology, 139(3), 263-270.

Martin, K. M., Larsen, P. D., Segal, R., & Marsland, C. P. (2004). Effective nonanatomical endoscopy training produces clinical airway endoscopy proficiency. Anesthesia & Analgesia, 99(3), 938-944.

2003

Journal - Research Article

Eames, P., Larsen, P. D., & Galletly, D. C. (2003). Comparison of ease of use of three automated external defibrillators by untrained lay people. Resuscitation, 58, 25-30.

Larsen, P. D., Tzeng, Y.-C., & Galletly, D. C. (2003). Inspiratory coupling to cardiac activity and to somatic afferent nerve stimulation in the anaesthetised rat. Autonomic Neuroscience, 108, 45-49.

Tzeng, Y.-C., Larsen, P. D., & Galletly, D. C. (2003). Cardioventilatory coupling in resting human subjects. Experimental Physiology, 88.6, 775-782.

Larsen, P. D., Tzeng, Y.-C., & Galletly, D. C. (2003). Quantal ventilatory variability during spontaneous breathing anaesthesia. British Journal of Anaesthesia, 91(2), 184-189.

Lafferty, C., Larsen, P., & Galletly, D. (2003). Resuscitation teaching in New Zealand schools. New Zealand Medical Journal, 116(1181). Retrieved from http://journal.nzma.org.nz/journal/116-1181/582/content.pdf

Ryan, A. D., Larsen, P. D., & Galletly, D. C. (2003). Comparison of heart rate variability in supine, and left and right lateral positions. Anaesthesia, 58, 432-436.

2002

Journal - Research Article

Larsen, P. D., Perrin, K., & Galletly, D. C. (2002). Patterns of external chest compression. Resuscitation, 53(3), 281-287.

Conference Contribution - Published proceedings: Abstract

Galletly, D. C., Larsen, P., & Pearson, J. (2002). Survey of training, knowledge and attitudes towards CPR in 16 year old New Zealand school children. Resuscitation 2002. 55, (pp. 118). [Abstract]

Mason, P., Galletly, D. C., & Larsen, P. (2002). Resuscitation in the school curriculum. Resuscitation 2002. 55, (pp. 117). Firenze: Congress of the European Resuscitation Council. [Abstract]

Larsen, P., & Galletly, D. C. (2002). Cardiovascular determination of inspiratory timing: A mechanism relevant to ventilatory collapse. Resuscitation 2002. 55, (pp. 79). [Abstract]

2001

Journal - Research Article

Lewis, C. D., Gebber, G. L., Larsen, P., & Barman, S. M. (2001). Long term correlations in the spike trains of medullary sympathetic neurons. Journal of Neurophysiology, 85, 1614-1622.

Larsen, P., Zhong, S., Gebber, G. L., & Barman, S. M. (2001). Sympathetic nerve and cardiovascular responses to chemical activation of the midbrain defense region. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 280, 1704-1712.

Larsen, P., & Galletly, D. C. (2001). Cardioventilatory coupling in heart rate variability: The value of standard analytical techniques. British Journal of Anaesthesia, 87, 819-826.

Galletly, D. C., & Larsen, P. (2001). Cardioventilatory coupling in heart rate variability: Methods for qualitative and quantitative determination. British Journal of Anaesthesia, 87, 827-833.

Galletly, D. C., & Larsen, P. (2001). Inspiratory timing during anaesthesia: A model of cardioventilatory coupling. British Journal of Anaesthesia, 86(6), 777-778.

Conference Contribution - Published proceedings: Abstract

Gebber, G. L., Larsen, P. D., Zhong, S., Lewis, C. D., & Barman, S. M. (2001). Coupling of arterial pulse and 10-Hz rhythm in sympathetic nerve discharge. FASEB Journal. 15. [Abstract]

Elder, D. E., Campbell, A., Larsen, P., & Galletly, D. C. (2001). Documentation of cardioventilatory coupling in preterm and term infants. Pediatric Research. 49(Supplement 4), (pp. 377). [Abstract]

2000

Journal - Research Article

Teoh, L. S., Gowardman, J. R., Larsen, P., Green, R., & Galletly, D. C. (2000). Glascow coma score: Differences in mortality among permutations of specific total scores. Intensive Care Medicine, 26, 157-161.

Lewis, C. D., Gebber, G. L., Zhong, S., Larsen, P., & Barman, S. M. (2000). Modes of baroreceptor-sympathetic co-ordination. Journal of Neurophysiology, 84, 1157-1167.

Larsen, P., Zhong, S., Lewis, C. D., Gebber, G. L., & Barman, S. M. (2000). Coupling of arterial pulse and 10-Hz rhythm in sympathetic nerve discharge. Brain Research, 883, 143-147.

Larsen, P., Zhong, S., Gebber, G. L., & Barman, S. M. (2000). Differential pattern in spinal sympathetic outflow in response to stimulation of the caudal medullary raphe. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 279, R210-R221.

Larsen, P., Lewis, C. D., Gebber, G. L., & Zhong, S. (2000). Partial spectral analysis of cardiac-related rhythm in sympathetic nerve discharge. Journal of Neurophysiology, 84, 1168-1179.

Conference Contribution - Published proceedings: Abstract

Larsen, P. D., Zhong, S., Gebber, G. L., & Barman, S. M. (2000). Differential pattern of spinal sympathetic outflow in response to electrical stimulation of caudal medullary raphe. FASEB Journal. 14. [Abstract]

1999

Journal - Research Article

Jordan, V. M. B., Grebe, S. K., Larsen, P. D., Stone, P., & Salmond, C. E. (1999). Acidic isoforms of chlorionic gonadotrophin in European and Samoan women are associated with hyperemesis gravidarum and may be thyrotoxic. Clinical Endocrinology, 50, 619-627.

Galletly, D. C., & Larsen, P. (1999). Determination of cardioventilatory coupling from heart rate and ventilatory time series. Research in Experimental Medicine, 199, 95-100.

Galletly, D. C., & Larsen, P. (1999). Ventilatory frequency variability in spontaneously breathing anaesthetised subjects. British Journal of Anaesthesia, 83, 552-563.

Larsen, P., & Galletly, D. C. (1999). Cardioventilatory coupling in the anaesthetised rat, rabbit and guinea pig a. Pflügers Archiv: European Journal of Physiology, 437, 910-916.

Larsen, P., Booth, P. E., & Galletly, D. C. (1999). Cardioventilatory coupling and atrial fibrillation. British Journal of Anaesthesia, 82, 685-690.

Larsen, P., Trent, P., & Galletly, D. C. (1999). Cardioventilatory coupling: the effects of IPPV. British Journal of Anaesthesia, 82, 546-550.

1998

Journal - Research Article

Gowardman, J. R., Montgomery, C., Thirwell, S., Shewan, J., Idema, A., Larsen, P. D., & Havill, J. V. (1998). Central venous catheter-related bloodstream infections: An analysis of incidence and risk factors in a cohort of 400 patients. Intensive Care Medicine, 24, 1034-1039.

Lewer, B., Larsen, P. D., Torrance, J. M., & Galletly, D. C. (1998). Artefactual episodic hypoxaemia during postoperative respiratory monitoring. Canadian Journal of Anesthesia / Journal canadien d'anesthésie, 45, 182-185.

Galletly, D. C., & Larsen, P. D. (1998). Relationship between cardioventilatory coupling and respiratory sinus arrhythmia. British Journal of Anaesthesia, 80, 164-168.

Journal - Professional & Other Non-Research Articles

Galletly, D. C., & Larsen, P. D. (1998). Observation and purpose: are ventilatory periodicals fine tuning or accidents of physiology? British Journal of Anaesthesia, 81, 108.

Lewer, B. M. F., Torrance, J. M., Galletly, D. C., & Larsen, P. D. (1998). Accuracy of transcutaneous carbon dioxide measurement. Canadian Journal of Anesthesia / Journal canadien d'anesthésie, 45, 186.

Lewer, B. M. F., Larsen, P. D., Torrance, J. M., & Galletly, D. C. (1998). Monitoring of hypoxaemic episodes in the postoperative period. Anaesthesia, 53, 826-827.

Menkes, D. B., & Larsen, P. (1998). Sodium valproate for tinnitus. Journal of Neurology, Neurosurgery & Psychiatry, 65, 803.

1997

Journal - Research Article

Galletly, D. C., & Larsen, P. (1997). Cardioventilatory coupling during anaesthesia. British Journal of Anaesthesia, 79(1), 35-40.

Galletly, D. C., & Larsen, P. (1997). Coupling of spontaneous ventilation to heart beat during benzodiazepine sedation. British Journal of Anaesthesia, 78(1), 100-101.

Larsen, P. D., Harty, M., Thiruchelvam, M., & Galletly, D. C. (1997). Spectral analysis of AC and DC components of the pulse photoplethysmograph at rest and during induction of anaesthesia. International Journal of Clinical Monitoring & Computing, 14(2), 89-95.

Conference Contribution - Published proceedings: Abstract

Larsen, P. D., Hulbert, T. G., & Galletly, D. C. (1997). Cardioventilatory coupling in three rodent species. Anaesthesia & Intensive Care, 25, (pp. 724-725). [Abstract]

Galletly, D. C., & Larsen, P. D. (1997). Cardioventilatory coupling and anaesthesia. Anaesthesia & Intensive Care, 25, (pp. 724-725). [Abstract]