Professor Anna Ranta

Contact Details
- Phone
- +64 4 806 1031
- anna.ranta@otago.ac.nz
- Position
- Professor and Head of Department
- Department
- Department of Medicine (Wellington)
- Qualifications
- MD PhD FRACP
- Research summary
- Stroke
Research
Professor Ranta’s research focuses on stroke and transient ischemic attack (TIA) epidemiology and service delivery optimisation, service integration, health equity, and knowledge translation.
She is the PI of the ongoing REGIONS Care Study. This is a nationwide HRC funded project (HRC 17/037 -$1.2 million)) that incorporates a stroke audit of NZ stroke services (acute and rehabilitation) and extended 1-year follow-up and data linkage with administrative data and focus groups to explore ethnic and geographic inequities in stroke care access and outcomes. The results of this project will advise future NZ stroke strategy to achieve the best outcomes for people with stroke.
She is also the co-PI for the B-SAFE Clinical Trial. This is a nationwide HRC funded project (HRC 16/330) looking at the impact of electronic decision support and the use of cardiac biomarkers on appropriate anticoagulation and patient outcomes. This study is specifically looking at patients with atrial fibrillation managed in primary care.
She is a named investigator for the Take Charge after Stroke. This is a nationwide HRC funded project (HRC 15/297) looking at the impact of motivational interviewing following stroke on stroke outcomes. Role on project: Co-investigator Other ongoing project topics include telestroke, secondary prevention following TIA, blood pressure optimisation following stroke, epidemiology of genetic muscle disorders, international collaboration in neuro and stroke epidemiology (GBD), and international stroke service provision (Lancet Commission for Stroke).
Publications
Warach, S. J., Ranta, A., Kim, J., Song, S. S., Wallace, A., Beharry, J., … Wilson, D., … Wu, T. Y. (2023). Symptomatic intracranial hemorrhage with tenecteplase vs alteplase in patients with acute ischemic stroke: The Comparative Effectiveness of Routine Tenecteplase vs Alteplase in Acute Ischemic Stroke (CERTAIN) collaboration. JAMA Neurology. Advance online publication. doi: 10.1001/jamaneurol.2023.1449
Rose, D., Cavalier, A., Kam, W., Cantrell, S., Lusk, J., Schrag, M., … Wu, T. Y., Ranta, A., … Mac Grory, B. (2023). Complications of intravenous tenecteplase versus alteplase for the treatment of acute ischemic stroke: A systematic review and meta-analysis [Review]. Stroke. Advance online publication. doi: 10.1161/strokeaha.122.042335
Denison, H. J., Corbin, M., Douwes, J., Thompson, S. G., Harwood, M., Davis, A., Fink, J. N., Barber, P. A., Gommans, J. H., … Levack, W., McNaughton, H., … Ranta, A. (2023). Ethnic differences in stroke outcomes in Aotearoa New Zealand: A national linkage study. International Journal of Stroke. Advance online publication. doi: 10.1177/17474930231164024
Kim, J., Cadilhac, D. A., Thompson, S., Gommans, J., Davis, A., Barber, P. A., Fink, J., Harwood, M., Levack, W., … Ranta, A. (2023). Comparison of stroke care costs in urban and nonurban hospitals and its association with outcomes in New Zealand: A nationwide economic evaluation. Stroke, 54, 848-856. doi: 10.1161/STROKEAHA.122.040869
Thompson, S. G., Barber, P. A., Gommans, J. H., Cadilhac, D. A., Davis, A., Fink, J. N., … Levack, W., … Ranta, A. (2022). Geographic disparities in stroke outcomes and service access: A prospective observational study. Neurology, 99(4), e414-e426. doi: 10.1212/wnl.0000000000200526
Warach, S. J., Ranta, A., Kim, J., Song, S. S., Wallace, A., Beharry, J., … Wilson, D., … Wu, T. Y. (2023). Symptomatic intracranial hemorrhage with tenecteplase vs alteplase in patients with acute ischemic stroke: The Comparative Effectiveness of Routine Tenecteplase vs Alteplase in Acute Ischemic Stroke (CERTAIN) collaboration. JAMA Neurology. Advance online publication. doi: 10.1001/jamaneurol.2023.1449
Journal - Research Article
Rose, D., Cavalier, A., Kam, W., Cantrell, S., Lusk, J., Schrag, M., … Wu, T. Y., Ranta, A., … Mac Grory, B. (2023). Complications of intravenous tenecteplase versus alteplase for the treatment of acute ischemic stroke: A systematic review and meta-analysis [Review]. Stroke. Advance online publication. doi: 10.1161/strokeaha.122.042335
Journal - Research Article
Denison, H. J., Corbin, M., Douwes, J., Thompson, S. G., Harwood, M., Davis, A., Fink, J. N., Barber, P. A., Gommans, J. H., … Levack, W., McNaughton, H., … Ranta, A. (2023). Ethnic differences in stroke outcomes in Aotearoa New Zealand: A national linkage study. International Journal of Stroke. Advance online publication. doi: 10.1177/17474930231164024
Journal - Research Article
Kim, J., Cadilhac, D. A., Thompson, S., Gommans, J., Davis, A., Barber, P. A., Fink, J., Harwood, M., Levack, W., … Ranta, A. (2023). Comparison of stroke care costs in urban and nonurban hospitals and its association with outcomes in New Zealand: A nationwide economic evaluation. Stroke, 54, 848-856. doi: 10.1161/STROKEAHA.122.040869
Journal - Research Article
Thompson, S. G., Barber, P. A., Gommans, J. H., Cadilhac, D. A., Davis, A., Fink, J. N., … Levack, W., … Ranta, A. (2022). Geographic disparities in stroke outcomes and service access: A prospective observational study. Neurology, 99(4), e414-e426. doi: 10.1212/wnl.0000000000200526
Journal - Research Article
Meinel, T. R., Wilson, D., Gensicke, H., Scheitz, J. F., Ringleb, P., Goganau, I., … Ranta, A., … for the International DOAC-IVT, TRISP, and CRCS-K-NIH Collaboration. (2023). Intravenous thrombolysis in patients with ischemic stroke and recent ingestion of direct oral anticoagulants. JAMA Neurology. Advance online publication. doi: 10.1001/jamaneurol.2022.4782
Journal - Research Article
Cadilhac, D. A., Bravata, D. M., Bettger, J. P., Mikulik, R., Norrving, B., Uvere, E. O., … Ranta, A., & Kilkenny, M. F. (2023). Stroke learning health systems: A topical narrative review with case examples. Stroke. Advance online publication. doi: 10.1161/strokeaha.122.036216
Journal - Research Other
Nguyen, T. N., Qureshi, M. M., Klein, P., Yamagami, H., Mikulik, R., Czlonkowska, A., … Ranta, A., … on behalf of the SVIN COVID-19 Global Stroke Registry. (2023). Global impact of the COVID-19 pandemic on stroke volumes and cerebrovascular events: One-year follow-up. Neurology, 100(4), e408-e422. doi: 10.1212/wnl.0000000000201426
Journal - Research Article
Garcia-Esperon, C., Wu, T. Y., Carraro da Nascimento, V., Yan, B., Kurunawai, C., Kleinig, T., … Ranta, A., … Fink, J., … on behalf of the ANZ Ultra-Long EVT Transfer Group, including Collecutt, W., & Krauss, M. (2023). Ultra-long transfers for endovascular thrombectomy: Mission impossible?: The Australia-New Zealand experience. Stroke, 54, 151-158. doi: 10.1161/strokeaha.122.040480
Journal - Research Article
Bravata, D. M., & Ranta, A. (2023). Artificial intelligence in clinical decisions support for stroke: Balancing opportunity with caution. Stroke, 54, 1517-1518. doi: 10.1161/STROKEAHA.123.043004
Journal - Research Other
Fasugba, O., Dale, S., McInnes, E., Cadilhac, D. A., Noetel, M., Coughlan, K., … Ranta, A., & Middleton, S. (2023). Evaluating remote facilitation intensity for multi-national translation of nurse-initiated stroke protocols (QASC Australasia): A protocol for a cluster randomised controlled trial. Implementation Science, 18, 2. doi: 10.1186/s13012-023-01260-9
Journal - Research Other
Dunphy, H., Garcia-Esperon, C., Hong, J. B., Manoczki, C., Wilson, D., Chew, B. L. A., Beharry, J., … Ranta, A., Fink, J. N., & Wu, T. Y. (2023). Endovascular thrombectomy for acute ischaemic stroke improves and maintains function in the very elderly: A multicentre propensity score matched analysis. European Stroke Journal, 8(1), 191-198. doi: 10.1177/23969873221145778
Journal - Research Article
Graham, F. P., Williman, J. A., Desha, L. N., Snell, D., Jones, B., Ingham, T. R., Latu, A., Maggo, J. K., Ranta, A., & Ziviani, J. (2023). Occupational performance coaching for children with neurodisability: A randomized controlled trial protocol. Canadian Journal of Occupational Therapy / Revue canadienne d’ergothérapie. Advance online publication. doi: 10.1177/00084174231160976
Journal - Research Other
Brown, K., El Husseini, N., Grimley, R., Ranta, A., Kass-Hout, T., Kaplan, S., & Kaufman, B. G. (2022). Alternative payment models and associations with stroke outcomes, spending, and service utilization: A systematic review. Stroke, 53, 268-278. doi: 10.1161/STROKEAHA.121.033983
Journal - Research Other
Scott, I. M., Manoczki, C., Swain, A. H., Ranjan, A., McGovern, M. G., Tyson, A. L. S., … Punter, M. M., & Ranta, A. (2022). Prehospital telestroke vs paramedic scores to accurately identify stroke reperfusion candidates: A cluster randomized controlled trial. Neurology, 99(19), e2125-e2136. doi: 10.1212/WNL.0000000000201104
Journal - Research Article
English, C., Hill, K., Cadilhac, D. A., Hackett, M. L., Lannin, N. A., Middleton, S., Ranta, A., … Campbell, B. C. V. (2022). Living clinical guidelines for stroke: Updates, challenges and opportunities. Medical Journal of Australia. Advance online publication. doi: 10.5694/mja2.51520
Journal - Research Other
Harwood, M., Ranta, A., Thompson, S., Ranta, S., Brewer, K., Gommans, J., … Fink, J., … Levack, W., & Douwes, J. (2022). Barriers to optimal stroke service care and solutions: A qualitative study engaging people with stroke and their whānau. New Zealand Medical Journal, 135(1556), 81-93. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Article
Shahjouei, S., Li, J., Koza, E., Abedi, V., Sadr, A. V., Chen, Q., … Ranta, A., & Zand, R. (2022). Risk of subsequent stroke among patients receiving outpatient vs inpatient care for transient ischemic attack: A systematic review and meta-analysis. JAMA Network Open, 5(1), e2136644. doi: 10.1001/jamanetworkopen.2021.36644
Journal - Research Article
Sasanejad, P., Hezarkhani, L. A., Arsang-Jang, S., Tsivgoulis, G., Ghoreishi, A., Kristian, B., … Ranta, A., … Azarpazhooh, M. R. (2021). Safety and outcomes of intravenous thrombolytic therapy in ischemic stroke patients with COVID-19: CASCADE initiative. Journal of Stroke & Cerebrovascular Diseases, 30(12), 106121. doi: 10.1016/j.jstrokecerebrovasdis.2021.106121
Journal - Research Article
Mahawish, K., Gommans, J., Kleinig, T., Lallu, B., Tyson, A., & Ranta, A. (2021). Switching to tenecteplase for stroke thrombolysis: Real-world experience and outcomes in a regional stroke network [Brief report]. Stroke, 52, e590-e593. doi: 10.1161/strokeaha.121.035931
Journal - Research Other
Nogueira, R., Qureshi, M. M., Abdalkader, M., Martins, S. O., Yamagami, H., Qiu, Z., … Ranta, A., … Wu, T. Y.-H., … on behalf of the SVIN COVID-19 Global Stroke Registry. (2021). Global impact of COVID-19 on stroke care and IV thrombolysis. Neurology, 96(23), e2824-e2838. doi: 10.1212/wnl.0000000000011885
Journal - Research Article
Balabanski, A. H., Dos Santos, A., Woods, J. A., Thrift, A. G., Kleinig, T. J., Suchy-Dicey, A., … Ranta, A., … Katzenellenbogen, J. M. (2021). The incidence of stroke in indigenous populations of countries with a very high human development index: A systematic review protocol. Frontiers in Neurology, 12, 661570. doi: 10.3389/fneur.2021.661570
Journal - Research Other
Ranta, A., & Hunter, R. (2021). Should TIA and minor stroke patients be kept out of the hospital? Neurology, 96(8). doi: 10.1212/wnl.0000000000011456
Journal - Research Other
McNaughton, H., Weatherall, M., McPherson, K., Fu, V., Taylor, W. J., McRae, A., Thomson, T., … Harwood, M., Ranta, A., Hanger, C., & Riley, J. (2021). The effect of the Take Charge intervention on mood, motivation, activation and risk factor management: Analysis of secondary data from the Taking Charge after Stroke (TaCAS) trial. Clinical Rehabilitation, 35(7), 1021-1031. doi: 10.1177/0269215521993648
Journal - Research Article
Owolabi, M. O., Thrift, A. G., Mahal, A., Ishida, M., Martins, S., Johnson, W. D., … on behalf of the Stroke Experts Collaboration Group, including Ranta, A. (2021). Primary stroke prevention worldwide: translating evidence into action. Lancet Public Health, 7(1), E74-E85. doi: 10.1016/S2468-2667(21)00230-9
Journal - Research Article
Barber, P. A., Wu, T. Y., & Ranta, A. (2020). Stroke reperfusion therapy following dabigatran reversal with idarucizumab in a national cohort. Neurology, 94, e1968-e1972. doi: 10.1212/wnl.0000000000009155
Journal - Research Article