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Contact Details

Phone
+64 3 479 5462
Email
simon.guan@otago.ac.nz
Position
Senior Lecturer
Department
Department of Oral Diagnostic and Surgical Sciences
Qualifications
BDS DClinDent(Oral Medicine) MBChB FOMAA
Research summary
Oral mucosal diseases and orofacial pain
Teaching
Postgraduate (DClinDent) and undergraduate (BDS)
Memberships
FOMMA
Clinical
Registered Oral Medicine Specialist In New Zealand and Clinical Supervisor for Oral Medicine DClinDent and BDS clinics

Research

As an Oral Medicine Specialist, I have a special interest in oral diseases with systemic complications and systemic diseases with oral manifestations.

My main research interest is in oral cancer, particularly developing prognostic or predictive molecular markers that can be used for assessment of the severity of the disease, prognosis and therapy.

Publications

Polonowita, A., Mei, L., & Guan, G. (2024). The deconstruction of chronic orofacial pain and a hiding inhibition pathway of orofacial pain: The trigeminal proprioceptive mesencephalic periaqueductal gray pathway. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1588), 67-79. Retrieved from https://nzmj.org.nz/

Avery, N., Fukushima, K., Guan, G., Praganta, J., Rich, A., Vincent, M., & Robertson, S. (2024). Familial aggregation of keratinising desquamative squamous metaplasia in the urinary tract. BJU International, 133(Suppl. 3), 15-17. doi: 10.1111/bju.16160

Guan, G., & Polonowita, A. (2023). Immunology and the oral cavity. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 319-323). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Polonowita, A., & Guan, G. (2023). Infection-related oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 217-219). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Polonowita, A., & Guan, G. (2023). Aphthae and recurrent aphthous stomatitis. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 213-215). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Guan, G., & Polonowita, A. (2023). Allergy and the mouth. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 103-105). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_24

Chapter in Book - Research

Guan, G., & Polonowita, A. (2023). Immunology and the oral cavity. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 319-323). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Chapter in Book - Research

Polonowita, A., & Guan, G. (2023). Aphthae and recurrent aphthous stomatitis. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 213-215). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Chapter in Book - Research

Polonowita, A., & Guan, G. (2023). Differential diagnosis of oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 205-207). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Chapter in Book - Research

Polonowita, A., & Guan, G. (2023). Infection-related oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 217-219). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Chapter in Book - Research

Polonowita, A., & Guan, G. (2023). Traumatic oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 209-211). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_50

Chapter in Book - Research

Avery, N., Fukushima, K., Guan, G., Praganta, J., Rich, A., Vincent, M., & Robertson, S. (2024). Familial aggregation of keratinising desquamative squamous metaplasia in the urinary tract. BJU International, 133(Suppl. 3), 15-17. doi: 10.1111/bju.16160

Journal - Research Article

Au, C., Li, J., Jin, L., Wu, T., Guan, G., & Mei, L. (2023). Non-attendance of appointments at the orthodontic clinic. Australasian Orthodontic Journal, 39(2), 185-193. doi: 10.2478/aoj-2023-0035

Journal - Research Article

Guan, G., Mei, L., Yu, C., Tan, Y., & Han, C. (2023). Patient-centred care attitudes and knowledge: A national study of BDS students in New Zealand. BMC Medical Education, 23, 516. doi: 10.1186/s12909-023-04496-7

Journal - Research Article

Li, M., & Guan, G. (2023). Profilometry and atomic force microscopy for surface characterization. Nano TransMed, 2(1), 69-73. doi: 10.26599/NTM.2023.9130017

Journal - Research Article

Han, C., Mei, L., Liu, A., Ya Mohammad Hassan, S., Polonowita, A., & Guan, G. (2022). Oral medicine services: A two-centre study of 99,603 patients between 2015 and 2020. Journal of International Medical Research, 50(8). doi: 10.1177/03000605221115384

Journal - Research Article

Polonowita, A., Guan, G., Thomson, W. M., & Martin-Hendrie, R. (2022). Using telehealth for oral medicine patient management during the COVID-19 lockdown. Oral Surgery, 15, 291-304. doi: 10.1111/ors.12721

Journal - Research Article

Ratnayake, J., Guan, G., Polonowita, A., Gray, A. R., Loch, C., Li, K. C., Waddell, J. N., Lyons, K., & Brunton, P. A. (2022). Measuring changes in jaw opening forces to assess the degree of improvement in patients with temporomandibular disorders. Applied Sciences, 12(3), 1224. doi: 10.3390/app12031224

Journal - Research Article

Yu, W. W., Goh, R., Cheong, E., Guan, G., Jin, C., Cannon, R. D., Farella, M., & Mei, L. (2022). Prevalence of halitosis among young adults in Dunedin, New Zealand. International Journal of Dental Hygiene, 20, 700-707. doi: 10.1111/idh.12609

Journal - Research Article

Wang, Y., Bai, S., Cheng, Q., Zeng, Y., Xu, X., & Guan, G. (2021). Naringenin promotes SDF-1/CXCR4 signaling pathway in BMSCs osteogenic differentiation. Folia Histochemica et Cytobiologica, 59(1), 66-73. doi: 10.5603/FHC.a2021.0008

Journal - Research Article

Won, J., Guan, G., Mei, L., Ma, T., Lai, Y., Zafar, S., Mei, M. L., & Thomson, W. M. (2021). A multicenter study of dental curricula in Asia/Pacific nations: The views and experiences of final-year dental students. Journal of Dental Education, 85, 660-668. doi: 10.1002/jdd.12515

Journal - Research Article

Guan, G., Lau, J., Yew, V., U, J., Qu, W., Lam, J., Polonowita, A., & Mei, L. (2020). Referrals by general dental practitioners and medical practitioners to oral medicine specialists in New Zealand: A study to develop protocol guidelines. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 130(1), 43-51.e5. doi: 10.1016/j.oooo.2020.03.050

Journal - Research Article

Guan, G., Mei, L., Polonowita, A., Hussaini, H., Seo, B., & Rich, A. M. (2020). Malignant transformation in oral lichen planus and lichenoid lesions: A 14-year longitudinal cohort study of 829 patients in New Zealand. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 130(4), 411-418. doi: 10.1016/j.oooo.2020.07.002

Journal - Research Article

Guo, J., Li, L., Guan, G., Bennani, F., & Mei, L. (2020). Oral health knowledge and practice among orthodontic clients in China and New Zealand. Canadian Journal of Dental Hygiene / Journal canadien de l'hygiène dentaire, 54(3), 124-132.

Journal - Research Article

Guo, J., Low, K. S., Mei, L., Li, J. H., Qu, W., & Guan, G. (2020). Use of traditional medicine for dental care by different ethnic groups in New Zealand. BMC Oral Health, 20, 280. doi: 10.1186/s12903-020-01272-7

Journal - Research Article

Guo, J., Yan, X., Li, S., Van der Walt, J., Guan, G., & Mei, L. (2020). Quantitative and qualitative analyses of orthodontic-related videos on YouTube. Angle Orthodontist, 90(3), 411-418. doi: 10.2319/082019-542.1

Journal - Research Article

Jiang, B., Xu, J., Zhou, Y., Mao, J., Guan, G., Xu, X., & Mei, L. (2020). Estrogen enhances osteogenic differentiation of human periodontal ligament stem cells by activating the Wnt/β-catenin signaling pathway. Journal of Craniofacial Surgery, 31, 583-587. doi: 10.1097/scs.0000000000006226

Journal - Research Article

Mei, L., Lai, Y., Lee, P., Ng, A., Tan, K., Zafar, S., & Guan, G. (2020). Final year dental students' career plans, work patterns, work-life balance and domestic life in New Zealand and Australia. European Journal of Dental Education, 24(4), 679-686. doi: 10.1111/eje.12556

Journal - Research Article

Ratnayake, J. T., Ross, E. D., Dias, G. J., Shanafelt, K. M., Taylor, S. S., Gould, M. L., Guan, G., & Cathro, P. R. (2020). Preparation, characterisation and in-vitro biocompatibility study of a bone graft developed from waste bovine teeth for bone regeneration. Materials Today Communications, 22, 100732. doi: 10.1016/j.mtcomm.2019.100732

Journal - Research Article

Ratnayake, J., Guan, G., Polonowita, A., Li, K. C., Gray, A., Waddell, J. N., Loch, C., & Brunton, P. A. (2020). Can the measurement of jaw-opening forces assist in the diagnosis of temporomandibular disorders? Journal of Oral & Facial Pain & Headache, 34(3), 199-205. doi: 10.11607/ofph.2587

Journal - Research Article

Xu, J., Zhao, X., Zeng, J., Yu, J.-H., Guan, S., Xu, X.-M., & Mei, L. (2020). Role of autophagy in the periodontal ligament reconstruction during orthodontic tooth movement in rats. Journal of Dental Sciences, 15, 351-363. doi: 10.1016/j.jds.2020.02.005

Journal - Research Article

Xu, X., Shum, M., Ting, A., Mei, L., & Guan, G. (2020). Estimation of jaw-opening forces, energy expenditure and jaw-opening patterns in adults. Archives of Oral Biology, 117, 104836. doi: 10.1016/j.archoralbio.2020.104836

Journal - Research Article

Guan, G., Bakr, M. M., Firth, N., & Love, R. M. (2018). Expression of cyclin D1 correlates with p27KIP1 and regulates the degree of oral dysplasia and squamous cell carcinoma differentiation. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 126(2), 174-183. doi: 10.1016/j.oooo.2018.01.015

Journal - Research Article

Wilson, E., Grant, B., Tobin-Stickings, R., Lewthwaite, H., Franklin, G., Oh, S., Guan, S., Borowsky, T., Thwaites, K., Leaper, T., Lee, J., Jack, S., & Sopoaga, F. (2018). Traditional medicine use in the Pacific community in Dunedin New Zealand. Pacific Health Dialog, 21(1), 17-26. doi: 10.26635/phd.2018.903

Journal - Research Article

Guan, G., & Firth, N. (2015). Oral manifestations as an early clinical sign of acute myeloid leukaemia: A case report. Australian Dental Journal, 60(1), 123-127. doi: 10.1111/adj.12272

Journal - Research Article

Polonowita, A., Mei, L., & Guan, G. (2024). The deconstruction of chronic orofacial pain and a hiding inhibition pathway of orofacial pain: The trigeminal proprioceptive mesencephalic periaqueductal gray pathway. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1588), 67-79. Retrieved from https://nzmj.org.nz/

Journal - Research Other

El Tantawi, M., Lam, W. Y. H., Giraudeau, N., Virtanen, J. I., Matanhire, C., Chifamba, T., … Hasmun, N., Guan, G., Polonowita, A., … Folayan, M. O. (2023). Teledentistry from research to practice: A tale of nineteen countries. Frontiers in Oral Health, 4, 1188557. doi: 10.3389/froh.2023.1188557

Journal - Research Other

Guan, G., Cannon, R. D., Coates, D. E., & Mei, L. (2023). Effect of the Rho-kinase/ROCK signaling pathway on cytoskeleton components. Genes, 14, 272. doi: 10.3390/genes14020272

Journal - Research Other

Guan, G., He, Y., & Mei, L. (2022). Atomic force microscopy: A nanobiotechnology for cellular research. Nano TransMed, 1, e9130004. doi: 10.26599/NTM.2022.9130004

Journal - Research Other

Guan, G., Rich, A. M., Polonowita, A., & Mei, L. (2022). Review of taste and taste disturbance in COVID-19 patients. New Zealand Medical Journal, 135(1549), 81-91. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Other

Li, B., Guan, G., Mei, L., Jiao, K., & Li, H. (2021). Pathological mechanism of chondrocytes and the surrounding environment during osteoarthritis of temporomandibular joint. Journal of Cellular & Molecular Medicine, 25, 4902-4911. doi: 10.1111/jcmm.16514

Journal - Research Other

Lv, N., Sun, M., Polonowita, A., Mei, L., & Guan, G. (2021). Management of oral medicine emergencies during COVID-19: A study to develop practice guidelines. Journal of Dental Sciences, 16, 493-500. doi: 10.1016/j.jds.2020.07.016

Journal - Research Other

Guan, G., Won, J., Mei, L., & Polonowita, A. (2020). Extensive adipose replacement of the parotid glands: An unusual presentation of sialadenosis: A case report and literature review. Oral Surgery, 13, 41-47. doi: 10.1111/ors.12442

Journal - Research Other

Sun, M., Lv, N., Xiao, Y., Li, J., & Guan, G. (2020). A rare case of accessory maxilla: A case report and literature review of Tessier no. 7 clefts. Journal of International Medical Research, 48(5), 1-9. doi: 10.1177/0300060520925680

Journal - Research Other

Bakr, M. M., Guan, S., Firth, N., & Love, R. M. (2018). Cyclin D1 and P27KIP1: The gatekeepers of dysplasia. Journal of Immunological Sciences, 2(3), 30-39. doi: 10.29245/2578-3009/2018/3.1142

Journal - Research Other

Guan, G., & Mei, L. (2018). A case series: Zinc deficiency as a potential contributor to oral dysgeusia. Modern Approaches in Dentistry & Oral Health Care, 2(5), 198-203. doi: 10.32474/MADOHC.2018.02.000146

Journal - Research Other

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