Dr Simone Bayer
Contact Details
- Phone
- +64 3 364 1790
- simone.bayer@otago.ac.nz
- Position
- Research Fellow
- Department
- Department of Medicine (Christchurch)
- Qualifications
- PhD (Pathology)
- Research summary
- Functional Gastrointestinal Disorders
- Memberships
- Treasurer of the New Zealand Society of Gastroenterology
Research
With a master's in Nutrition Science and a PhD in Pathology, Simone is highly interested in the complex field of Functional Gastrointestinal Disorders, specifically Irritable Bowel Syndrome (IBS), Functional Constipation (FC), and Functional Diarrhoea (FD).
She has conducted a large clinical trial on the effect of two SunGold® kiwifruit on gastrointestinal comfort and aims to analyse mRNA from colon biopsies to detect differences between FD, FC, and IBS. Furthermore, she is collaborating with Nicolas Talley from the University of Newcastle, Australia, to detect differences between these disorders through histology.
Publications
Peeters, W. M., Gram, M., Dias, G. J., Vissers, M. C. M., Hampton, M. B., Dickerhof, N., Bekhit, A. E., … Bayer, S., … Sheard, P. W., Danielson, K. M., … Cornwall, J., & Rowlands, D. S. (2023). Changes to insulin sensitivity in glucose clearance systems and redox following dietary supplementation with a novel cysteine-rich protein: A pilot randomized controlled trial in humans with type-2 diabetes. Redox Biology, 67, 102918. doi: 10.1016/j.redox.2023.102918
Simon, M. H., Heenan, P. E., Frampton, C., Bayer, S., Keenan, J. I., de Boer, N. K., Roy, N. C., … Gearry, R. B. (2023). Economic living standard and abdominal pain mediate the association between functional gastrointestinal disorders and depression or anxiety. Neurogastroenterology & Motility, 35, e14465. doi: 10.1111/nmo.14465
Bayer, S. B., Heenan, P., Frampton, C., Wall, C. L., Drummond, L. N., Roy, N. C., & Gearry, R. B. (2022). Two gold kiwifruit daily for effective treatment of constipation in adults: A randomized clinical trial. Nutrients, 14, 4146. doi: 10.3390/nu14194146
Bayer, S. B., Frampton, C. M., Gearry, R. B., & Barbara, G. (2022). Habitual green kiwifruit consumption is associated with a reduction in upper gastrointestinal symptoms: A systematic scoping review. Advances in Nutrition, 13, 846-856. doi: 10.1093/advances/nmac025
Dachs, G. U., Gandhi, J., Wohlrab, C., Carr, A. C., Morrin, H. R., Pullar, J. M., Bayer, S. B., Eglinton, T. W., Robinson, B. A., & Vissers, M. C. M. (2021). Vitamin C administration by intravenous infusion increases tumor ascorbate content in patients with colon cancer: A clinical intervention study. Frontiers in Oncology, 10, 600715. doi: 10.3389/fonc.2020.600715
Peeters, W. M., Gram, M., Dias, G. J., Vissers, M. C. M., Hampton, M. B., Dickerhof, N., Bekhit, A. E., … Bayer, S., … Sheard, P. W., Danielson, K. M., … Cornwall, J., & Rowlands, D. S. (2023). Changes to insulin sensitivity in glucose clearance systems and redox following dietary supplementation with a novel cysteine-rich protein: A pilot randomized controlled trial in humans with type-2 diabetes. Redox Biology, 67, 102918. doi: 10.1016/j.redox.2023.102918
Journal - Research Article
Simon, M. H., Heenan, P. E., Frampton, C., Bayer, S., Keenan, J. I., de Boer, N. K., Roy, N. C., … Gearry, R. B. (2023). Economic living standard and abdominal pain mediate the association between functional gastrointestinal disorders and depression or anxiety. Neurogastroenterology & Motility, 35, e14465. doi: 10.1111/nmo.14465
Journal - Research Article
Bayer, S. B., Heenan, P., Frampton, C., Wall, C. L., Drummond, L. N., Roy, N. C., & Gearry, R. B. (2022). Two gold kiwifruit daily for effective treatment of constipation in adults: A randomized clinical trial. Nutrients, 14, 4146. doi: 10.3390/nu14194146
Journal - Research Article
Dachs, G. U., Gandhi, J., Wohlrab, C., Carr, A. C., Morrin, H. R., Pullar, J. M., Bayer, S. B., Eglinton, T. W., Robinson, B. A., & Vissers, M. C. M. (2021). Vitamin C administration by intravenous infusion increases tumor ascorbate content in patients with colon cancer: A clinical intervention study. Frontiers in Oncology, 10, 600715. doi: 10.3389/fonc.2020.600715
Journal - Research Article
Heenan, P., Creemers, R. H., Sharma, S., Keenan, J., Bayer, S., Young, W., … Skidmore, P. M., … Roy, N., Gearry, R. B., & COMFORT Cohort Collaborators. (2020). Cohort profile: The Christchurch IBS cOhort to investigate Mechanisms FOr gut Relief and improved Transit (COMFORT). Inflammatory Intestinal Diseases, 5(3), 132-143. doi: 10.1159/000508160
Journal - Research Article
Bayer, S. B., Gearry, R. B., & Drummond, L. N. (2018). Putative mechanisms of kiwifruit on maintenance of normal gastrointestinal function. Critical Reviews in Food Science & Nutrition, 58(14), 2432-2452. doi: 10.1080/10408398.2017.1327841
Journal - Research Article
Pullar, J. M., Bayer, S., & Carr, A. C. (2018). Appropriate handling, processing and analysis of blood samples is essential to avoid oxidation of vitamin C to dehydroascorbic acid. Antioxidants, 7(2), 29. doi: 10.3390/antiox7020029
Journal - Research Article
Carr, A. C., Rosengrave, P. C., Bayer, S., Chambers, S., Mehrtens, J., & Shaw, G. M. (2017). Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes. Critical Care, 21, 300. doi: 10.1186/s13054-017-1891-y
Journal - Research Article
Bayer, S. B., Low, F. M., Hampton, M. B., & Winterbourn, C. C. (2016). Interactions between peroxiredoxin 2, hemichrome and the erythrocyte membrane. Free Radical Research, 50(12), 1329-1339. doi: 10.1080/10715762.2016.1241995
Journal - Research Article
Bayer, S. B., Hampton, M. B., & Winterbourn, C. C. (2015). Accumulation of oxidized peroxiredoxin 2 in red blood cells and its prevention. Transfusion, 55(8), 1909-1918. doi: 10.1111/trf.13039
Journal - Research Article
Bayer, S. B., Maghzal, G., Stocker, R., Hampton, M. B., & Winterbourn, C. C. (2013). Neutrophil-mediated oxidation of erythrocyte peroxiredoxin 2 as a potential marker of oxidative stress in inflammation. FASEB Journal, 27(8), 3315-3322. doi: 10.1096/fj.13-227298
Journal - Research Article
Bayer, S. B., Frampton, C. M., Gearry, R. B., & Barbara, G. (2022). Habitual green kiwifruit consumption is associated with a reduction in upper gastrointestinal symptoms: A systematic scoping review. Advances in Nutrition, 13, 846-856. doi: 10.1093/advances/nmac025
Journal - Research Other
Heenan, P. E., Keenan, J. I., Bayer, S., Simon, M., & Gearry, R. B. (2020). Irritable bowel syndrome and the gut microbiota. Journal of the Royal Society of New Zealand, 50(3), 470-490. doi: 10.1080/03036758.2019.1695635
Journal - Research Other