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Contact Details

Phone
+64 3 470 3547
Email
regis.lamberts@otago.ac.nz
Position
Associate Professor, Deputy HOD (Teaching)
Department
Department of Physiology
Qualifications
BSc MSc PhD
Research summary
Cardiovascular physiology

Research

How the heart maintains its pump function under conditions of stress has been the focus of my research career.

In the last decade my research has focused on determining the changes in autonomic regulation and heart function in obesity and diabetes. More recently this has extended to determining the functional interaction between epicardial adipose tissue and the heart, especially in relation to development of cardiac arrhythmias and obesity. To this end, functional biomedical data at cellular and organ level, human myocardial and clinical data are obtained through HeartOtago.

This translational knowledge creates the platform that is vital for the development of specific therapeutics for the increasing cohort of individuals with metabolic disease and arrhythmias to improve their heart health.

Publications

Ashley, Z., Futi, T., Van Hout, I., Coffey, S., Schwenke, D. O., Bahn, A., & Lamberts, R. R. (2022). Cardiac fibrosis in right atrial tissue is not different in male Pasifika and Pākehā cardiac surgery patients in Aotearoa. Pacific Journal of Medical Sciences, 22(2), 11-30. Journal - Research Article

Aitken-Buck, H. M., Moore, M., Whalley, G. A., Lohner, L., Ondruschka, B., Coffey, S., … Lamberts, R. R. (2022). Estimating heart mass from heart volume as measured from post-mortem computed tomography. Forensic Science, Medicine & Pathology, 18, 333-342. doi: 10.1007/s12024-022-00478-1 Journal - Research Article

Waddell, H. M. M., Moore, M., Herbert-Olsen, M. A., Stiles, M. K., Tse, R. D., Coffey, S., Lamberts, R. R., & Aitken-Buck, H. M. (2022). Identifying sex differences in predictors of epicardial fat cell morphology. Adipocyte, 11(1), 325-334. doi: 10.1080/21623945.2022.2073854 Journal - Research Article

Gonano, L. A., Aitken-Buck, H. M., Chakraborty, A. D., Worthington, L. P. I., Cully, T. R., Lamberts, R. R., … Jones, P. P. (2022). Regulation of cardiac ryanodine receptor function by the cyclic-GMP dependent protein kinase G. Current Research in Physiology, 5, 171-178. doi: 10.1016/j.crphys.2022.03.004 Journal - Research Article

Satthenapalli, R., Lee, S., Bellae Papannarao, J., Hore, T. A., Chakraborty, A., Jones, P. P., Lamberts, R. R., & Katare, R. (2022). Stage-specific regulation of signalling pathways to differentiate pluripotent stem cells to cardiomyocytes with ventricular lineage. Stem Cell Research & Therapy, 13(1), 185. doi: 10.1186/s13287-022-02845-9 Journal - Research Article

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