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Contact Details

Phone
64 3 378 6078
Email
tim.anderson@otago.ac.nz
Position
Professor
Department
Department of Medicine (Christchurch)
Qualifications
BSc MBChB (Otago) FRACP
Research summary
Movement Disorders and Brain Research

Research

I am the Clinical Director of the NZ Brain Research Institute. I am a Neurologist, with subspecialty expertise in Movement Disorders including Parkinson’s, Huntington’s disease and botulinum toxin therapy.

My research interests and expertise are:

  • establishing biomarkers of cognitive decline to mild cognitive impairment (MCI) and dementia, particularly advanced MRI markers in Parkinson’s disease but also other dementias;
  • eye movements in PD and other neurological disorders, in collaboration with Dr M MacAskill,
  • clinical biomarkers of progression in Huntington’s disease, and
  • speech and swallowing disorders in health and neurological disorders.

I regularly conduct clinical pharmaceutical trials in Parkinson’s and other neurological disorders This has enabled patients not only to have early access to new treatments but also and regular clinical review and oversight.

Publications

Aye, W. W. T., Stark, M. R., Horne, K.-L., Livingston, L., Grenfell, S., Myall, D. J., Pitcher, T. L., Almuqbel, M. M., Keenan, R. J., … Dalrymple-Alford, J. C., Anderson, T. J., Le Heron, C., & Melzer, T. R. (2024). Early-phase amyloid PET reproduces metabolic signatures of cognitive decline in Parkinson's disease. Alzheimer's & Dementia, 16(2), e12601. doi: 10.1002/dad2.12601 Journal - Research Article

Le Heron, C., Horne, K.-L., MacAskill, M. R., Livingstone, L., Melzer, T. R., Myall, D., Pitcher, T., Dalrymple-Alford, J., Anderson, T., & Harrison, S. (2024). Cross-sectional and longitudinal association of clinical and neurocognitive factors with apathy in patients with Parkinson disease. Neurology, 102, e209301. doi: 10.1212/wnl.0000000000209301 Journal - Research Article

Bernhardt, I., Frajman, L. E., Ryder, B., Andersen, E., Wilson, C., McKeown, C., Anderson, T., … Drake, K. M., Leask, M., Yardley, A.-M., Merriman, T., Robertson, S., … Glamuzina, E. (2024). Further delineation of short chain enoyl-CoA hydratase deficiency in the Pacific population. Molecular Genetics & Metabolism, 142, 108508. doi: 10.1016/j.ymgme.2024.108508 Journal - Research Article

Kim, J. J., Vitale, D., Otani, D. V., Lian, M. M., Heilbron, K., the 23andMe Research Team, … the Global Parkinson's Genetic Program (GP2), including Anderson, T. J., Pitcher, T. L., … Mata, I. (2024). Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease. Nature Genetics, 56, 27-36. doi: 10.1038/s41588-023-01584-8 Journal - Research Article

Ganderton, J., Pitcher, T., Melzer, T., Philips, S., Harris, A., Dobson, R., Anderson, T., … Dalrymple-Alford, J. (2023). Reflex tears to target alpha-synuclein in Parkinson’s disease. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference Conference Contribution - Published proceedings: Abstract

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