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Contact Details

Phone
+64 3 470 9430
Email
paul.glue@otago.ac.nz
Position
Hazel Buckland Professor
Department
Department of Psychological Medicine (Dunedin)
Qualifications
MB ChB(Otago) MD(Bristol) MRCPsych
Research summary
Psychological Medicine

Research

  • Psychopharmacology
  • Pharmacokinetics/Pharmacodynamics
  • Clinical Trial Design
  • Translational Medicine
  • Clinical Pharmacology

Development of novel therapeutics for affective disorders and learning disorders Biomarkers in anxiety.

Professor Glue's research focuses on clinical and basic science. His areas of interest include the pharmacology of drug treatments in psychiatry and the investigation of disease mechanisms in neurological and psychiatric disorders. He is also interested in technical aspects of clinical trial design, including trialling simulation and modelling. He has published extensively, with more than 250 papers and book chapters to his name.

Publications

Gale, C., Glue, P., & Barak, Y. (2026). Letter to the Editor regarding 'The future of psychiatry: Reclaiming relevance in an era of technological and systemic transformation'. Australian & New Zealand Journal of Psychiatry. Advance online publication. doi: 10.1177/00048674261465198 Journal - Research Other

Shadli, S. M., Nasrollahi, N., Young, C. K., Schuck, G. S. R., Whatson, M. G., Kawe, T., Neehoff, S., Beaglehole, B., Glue, P., & McNaughton, N. (2026). Ketamine effects on EEG and their links to therapy differ across treatment-resistant major depression, post-traumatic stress disorder, and obsessive-compulsive disorder. International Journal of Neuropsychopharmacology. Advance online publication. doi: 10.1093/ijnp/pyag037 Journal - Research Article

Glozier, N., Morris, R., Stratton, E., Somogyi, A., Sarma, S., Rodgers, A., … Glue, P., … Loo, C. K. (2026). Effectiveness and safety of repeat dose subcutaneous ketamine for treatment-resistant depression, and the impact of prior ketamine treatment: Open label extension of the KADS study. British Journal of Psychiatry, 1-7. Advance online publication. doi: 10.1192/bjp.2026.10692 Journal - Research Article

Costello, H., Reeves, S., Glue, P., Young, A. H., & Howard, R. (2026). Depression in neurodegenerative disease: Neurobiological mechanisms and emerging treatments. Molecular Psychiatry. Advance online publication. doi: 10.1038/s41380-026-03728-8 Journal - Research Other

Glue, P., & Beaglehole, B. (2026). Ketamine dosing across clinical indications: A narrative review organized by proposed NMDA-related mechanisms. Journal of Clinical Pharmacology, 66(6), e70225. doi: 10.1002/jcph.70225 Journal - Research Article

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