Grattan Laboratory

Publications

Brown, R. S. E., Jacobs, I. M., Khant Aung, Z., Knowles, P. J., Grattan, D. R., & Ladyman, S. R. (2023). High fat diet-induced maternal obesity in mice impairs peripartum maternal behaviour. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13350 Journal - Research Article

Smiley, K. O., Phillipps, H. R., Fang, C., Brown, R. S. E., & Grattan, D. R. (2023). Mating-induced prolactin surge is not required for subsequent neurogenesis in male mice. Frontiers in Behavioral Neuroscience, 17, 1227726. doi: 10.3389/fnbeh.2023.1227726 Journal - Research Article

Goffin, V., Becu-Villalobos, D., Popovic, V., & Grattan, D. R. (2023). Editorial: Towards targeting prolactin signaling in human diseases: Stimulate or inhibit? Frontiers in Endocrinology, 14, 1213895. doi: 10.3389/fendo.2023.1213895 Journal - Research Other

Wall, E. G., Desai, R., Khant Aung, Z., Yeo, S. H., Grattan, D. R., Handelsman, D. J., & Herbison, A. E. (2023). Unexpected plasma gonadal steroid and prolactin levels across the mouse estrous cycle. Endocrinology, bqad070. Advance online publication. doi: 10.1210/endocr/bqad070 Journal - Research Article

Hackwell, E. C. R., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2023). Mechanisms of lactation-induced infertility in female mice. Endocrinology. Advance online publication. doi: 10.1210/endocr/bqad049 Journal - Research Article

Hassan, M., Grattan, D. R., & Leitch, B. (2023). Developmental inhibitory changes in the primary somatosensory cortex of the stargazer mouse model of absence epilepsy. Biomolecules, 13, 186. doi: 10.3390/biom13010186 Journal - Research Article

Georgescu, T., Khant Aung, Z., Grattan, D. R., & Brown, R. S. E. (2022). Prolactin-mediated restraint of maternal aggression in lactation. PNAS, 119(6), e2116972119. doi: 10.1073/pnas.2116972119 Journal - Research Article

Kamstra, K., Rizwan, M. Z., Grattan, D. R., Horsfield, J. A., & Tups, A. (2022). Leptin regulates glucose homeostasis via the canonical Wnt pathway in the zebrafish. FASEB Journal, 36, e22207. doi: 10.1096/fj.202101764R Journal - Research Article

Phillipps, H. R., Khant Aung, Z., & Grattan, D. R. (2022). Elevated prolactin secretion during proestrus in mice: Absence of a defined surge. Journal of Neuroendocrinology, 34, e13129. doi: 10.1111/jne.13129 Journal - Research Article

Radecki, K. C., Ford, M. J., Phillipps, H. R., Lorenson, M. Y., Grattan, D. R., Yamanaka, Y., & Walker, A. M. (2022). Multiple cell types in the oviduct express the prolactin receptor. FASEB BioAdvances, 4, 485-504. doi: 10.1096/fba.2022-00004 Journal - Research Article

Smiley, K. O., Brown, R. S. E., & Grattan, D. R. (2022). Prolactin action is necessary for parental behavior in male mice. Journal of Neuroscience. Advance online publication. doi: 10.1523/jneurosci.0558-22.2022 Journal - Research Article

Swart, J. M., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2022). Pups and prolactin are rewarding to virgin female and pregnant mice. Journal of Neuroendocrinology, e13232. Advance online publication. doi: 10.1111/jne.13232 Journal - Research Article

Aoki, M., Gamayun, I., Wyatt, A., Grünewald, R., Simon-Thomas, M., Philipp, S. E., … Grattan, D. R., & Boehm, U. (2021). Prolactin-sensitive olfactory sensory neurons regulate male preference in female mice by modulating responses to chemosensory cues. Science Advances, 7(41), eabg4074. doi: 10.1126/sciadv.abg4074 Journal - Research Article

Khant Aung, Z., Kokay, I. C., Grattan, D. R., & Ladyman, S. R. (2021). Prolactin-induced adaptation in glucose homeostasis in mouse pregnancy is mediated by the pancreas and not in the forebrain. Frontiers in Endocrinology, 12, 765976. doi: 10.3389/fendo.2021.765976 Journal - Research Article

Ladyman, S. R., Carter, K. M., Gillett, M. L., Khant Aung, Z., & Grattan, D. R. (2021). A reduction in voluntary physical activity in early pregnancy in mice is mediated by prolactin. eLIFE, 10, e62260. doi: 10.7554/eLife.62260 Journal - Research Article

Ladyman, S. R., Larsen, C. M., Taylor, R. S., Grattan, D. R., & McCowan, L. M. E. (2021). Case–control study of prolactin and placental lactogen in SGA pregnancies. Reproduction & Fertility, 2(4), 244-250. doi: 10.1530/RAF-21-0020 Journal - Research Article

Nair, B. B., Khant Aung, Z., Porteous, R., Prescott, M., Glendining, K. A., Jenkins, D. E., Augustine, R. A., Silva, M. S. B., Yip, S. H., Bouwer, G. T., Brown, C. H., Jasoni, C. L., Campbell, R. E., Bunn, S. J., Anderson, G. M., Grattan, D. R., Herbison, A. E., & Iremonger, K. J. (2021). Impact of chronic variable stress on neuroendocrine hypothalamus and pituitary in male and female C57BL/6J mice. Journal of Neuroendocrinology, 33, e12972. doi: 10.1111/jne.12972 Journal - Research Article

Swart, J. M., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2021). Changes in maternal motivation across reproductive states in mice: A role for prolactin receptor activation on GABA neurons. Hormones & Behavior, 135, 105041. doi: 10.1016/j.yhbeh.2021.105041 Journal - Research Article

Grattan, D. R., & Ladyman, S. R. (2020). Neurophysiological and cognitive changes in pregnancy. In E. A. P. Steegers, M. J. Cipolla & E. C. Miller (Eds.), Handbook of clinical neurology (Vol. 171): Neurology and pregnancy: Pathophysiology and patient care. (pp. 25-55). Amsterdam, The Netherlands: Elsevier. doi: 10.1016/B978-0-444-64239-4.00002-3 Chapter in Book - Research

Barad, Z., Khant Aung, Z., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2020). Impaired prolactin transport into the brain and functional responses to prolactin in aged male mice. Journal of Neuroendocrinology, 32, e12889. doi: 10.1111/jne.12889 Journal - Research Article

Garratt, M., Try, H., Smiley, K. O., Grattan, D. R., & Brooks, R. C. (2020). Mating in the absence of fertilization promotes a growth-reproduction versus lifespan trade-off in female mice. PNAS, 117(27), 15748-15754. doi: 10.1073/pnas.2003159117 Journal - Research Article

Georgescu, T., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2020). Acute effects of prolactin on hypothalamic prolactin receptor expressing neurones in the mouse. Journal of Neuroendocrinology, 32, e12908. doi: 10.1111/jne.12908 Journal - Research Article

Gustafson, P., Ladyman, S. R., McFadden, S., Larsen, C., Khant Aung, Z., Brown, R. S. E., Bunn, S. J., & Grattan, D. R. (2020). Prolactin receptor-mediated activation of pSTAT5 in the pregnant mouse brain. Journal of Neuroendocrinology, 32, e12901. doi: 10.1111/jne.12901 Journal - Research Article

Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2020). Pregnancy-induced adaptation of central sensitivity to leptin and insulin. Molecular & Cellular Endocrinology, 516, 110933. doi: 10.1016/j.mce.2020.110933 Journal - Research Article

Kokay, I. C., Grattan, D. R., & Murray, J. F. (2020). Prolactin maintains transient melanin-concentrating hormone expression in the medial preoptic area during established lactation. Journal of Neuroendocrinology, 32, e12827. doi: 10.1111/jne.12827 Journal - Research Article

Lopez-Vicchi, F., Ladyman, S. R., Ornstein, A. M., Gustafson, P., Knowles, P., Luque, G. M., Grattan, D. R., & Becu-Villalobos, D. (2020). Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake. FASEB Journal, 34, 3902-3914. doi: 10.1096/fj.201902357R Journal - Research Article

Paige, C., Barba-Escobedo, P. A., Mecklenburg, J., Patil, M., Goffin, V., Grattan, D. R., … Price, T. J. (2020). Neuroendocrine mechanisms governing sex differences in hyperalgesic priming involve prolactin receptor sensory neuron signaling. Journal of Neuroscience, 40(37), 7080-7090. doi: 10.1523/jneurosci.1499-20.2020 Journal - Research Article

Silva, J. F., Henriques, P. C., Campideli-Santana, A. C., Araujo-Lopes, R., Aquino, N. S. S., Hipolito, L. T. M., … Grattan, D. R., & Szawka, R. E. (2020). Estradiol potentiates but is not essential for prolactin-induced suppression of luteinizing hormone pulses in female rats. Endocrinology, 161, 1-14. doi: 10.1210/endocr/bqaa022 Journal - Research Article

Stagkourakis, S., Smiley, K. O., Williams, P., Kakadellis, S., Ziegler, K., Bakker, J., Brown, R. S. E., … Grattan, D. R., & Broberger, C. (2020). A neuro-hormonal circuit for paternal behavior controlled by a hypothalamic network oscillation. Cell, 182, 960-975. doi: 10.1016/j.cell.2020.07.007 Journal - Research Article

Yip, S. H., Araujo-Lopes, R., Szawka, R. E., York, J., Hyland, B., Grattan, D. R., & Bunn, S. J. (2020). Morphological plasticity of the tuberoinfundibular dopaminergic neurons in the rat during the estrous cycle and lactation. Journal of Neuroendocrinology, 32(11), e12884. doi: 10.1111/jne.12884 Journal - Research Article

Smiley, K. O., Ladyman, S. R., Gustafson, P., Grattan, D. R., & Brown, R. S. E. (2019). Neuroendocrinology and adaptive physiology of maternal care. In L. M. Coolen & D. R. Grattan (Eds.), Neuroendocrine regulation of behavior: Current topics in behavioral neurosciences (Vol. 43). (pp. 161-210). Cham, Switzerland: Springer. doi: 10.1007/7854_2019_122 Chapter in Book - Research

Aoki, M., Wartenberg, P., Grūnewald, R., Phillipps, H. R., Wyatt, A., Grattan, D. R., & Boehm, U. (2019). Widespread cell-specific prolactin receptor expression in multiple murine organs. Endocrinology, 60(11), 2587-2599. doi: 10.1210/en.2019-00234 Journal - Research Article

Aquino, N. S. S., Kokay, I. C., Perez, C. T., Ladyman, S. R., Henriques, P. C., Silva, J. F., … Grattan, D. R., & Szawka, R. E. (2019). Kisspeptin stimulation of prolactin secretion requires Kiss1 receptor but not in tuberoinfundibular dopaminergic neurons. Endocrinology, 160(3), 522-533. doi: 10.1210/en.2018-00932 Journal - Research Article

Augustine, R. A., Knowles, P. J., Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2019). Impaired hypothalamic leptin sensitivity in pseudopregnant rats treated with chronic prolactin to mimic pregnancy. Journal of Neuroendocrinology, 31, e12702. doi: 10.1111/jne.12702 Journal - Research Article

Brown, R. S. E., Khant Aung, Z., Phillipps, H. R., Barad, Z., Lein, H.-J., Boehm, U., Szawka, R. E., & Grattan, D. R. (2019). Acute suppression of LH secretion by prolactin in female mice is mediated by kisspeptin neurons in the arcuate nucleus. Endocrinology, 160(5), 1323-1332. doi: 10.1210/en.2019-00038 Journal - Research Article

Kirk, S. E., Grattan, D. R., & Bunn, S. J. (2019). The median eminence detects and responds to circulating prolactin in the male mouse. Journal of Neuroendocrinology, 31, e12733. doi: 10.1111/jne.12733 Journal - Research Article

Patil, M., Belugin, S., Mecklenburg, J., Wangzhou, A., Paige, C., Barba-Escobedo, P. A., … Grattan, D., … Akopian, A. N. (2019). Prolactin regulates pain responses via a female-selective nociceptor-specific mechanism. iScience, 20, 449-465. doi: 10.1016/j.isci.2019.09.039 Journal - Research Article

Patil, M., Hovhannisyan, A. H., Wangzhou, A., Mecklenburg, J., Koek, W., Goffin, V., Grattan, D., … Akopian, A. N. (2019). Prolactin receptor expression in mouse dorsal root ganglia neuronal subtypes is sex-dependent. Journal of Neuroendocrinology, 31, e12759. doi: 10.1111/jne.12759 Journal - Research Article

Phillipps, H. R., Rand, C. J., Brown, R. S. E., Kokay, I. C., Stanton, J.-A., & Grattan, D. R. (2019). Prolactin regulation of insulin-like growth factor 2 gene expression in the adult mouse choroid plexus. FASEB Journal, 33, 6115-6128. doi: 10.1096/fj.201802262R Journal - Research Article

Skinner, N. J., Rizwan, M. Z., Grattan, D. R., & Tups, A. (2019). Chronic light cycle disruption alters central insulin and leptin signaling as well as metabolic markers in male mice. Endocrinology, 160(10), 2257-2270. doi: 10.1210/en.2018-00935 Journal - Research Article

Yip, S. H., Romanò, N., Gustafson, P., Hodson, D. J., Williams, E. J., Kokay, I. C., … Grattan, D. R., & Bunn, S. J. (2019). Elevated prolactin during pregnancy drives a phenotypic switch in mouse hypothalamic dopaminergic neurons. Cell Reports, 26(7), 1787-1799.e5. doi: 10.1016/j.celrep.2019.01.067 Journal - Research Article

Bernard, V., Lamothe, S., Beau, I., Guillou, A., Martin, A., Le Tissier, P., Grattan, D., … Binart, N. (2018). Autocrine actions of prolactin contribute to the regulation of lactotroph function in vivo. FASEB Journal, 32(9), 4791-4797. doi: 10.1096/fj.201701111RR Journal - Research Article

Grattan, D. R. (2018). Coordination or coincidence? The relationship between prolactin and gonadotropin secretion. Trends in Endocrinology & Metabolism, 29(1), 3-5. doi: 10.1016/j.tem.2017.11.004 Journal - Research Article

Kokay, I. C., Wyatt, A., Phillipps, H. R., Aoki, M., Hermans-Borgmeyer, I., Boehm, U., & Grattan, D. R. (2018). Analysis of prolactin receptor expression in the murine brain using a novel prolactin receptor reporter mouse. Journal of Neuroendocrinology, 30, e12634. doi: 10.1111/jne.12634 Journal - Research Article

Krishnan, M., Major, T. J., Topless, R. K., Dewes, O., Yu, L., Thompson, J. M. D., … Stamp, L. K., … Wilcox, P., Grattan, D., … Merriman, T. R. (2018). Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people living in Aotearoa/New Zealand. Diabetologia, 61(7), 1603-1613. doi: 10.1007/s00125-018-4623-1 Journal - Research Article

Ladyman, S. R., Carter, K. M., & Grattan, D. R. (2018). Energy homeostasis and running wheel activity during pregnancy in the mouse. Physiology & Behavior, 194, 83-94. doi: 10.1016/j.physbeh.2018.05.002 Journal - Research Article

Ladyman, S. R., Khant Aung, Z., & Grattan, D. R. (2018). Impact of pregnancy and lactation on the long-term regulation of energy balance in female mice. Endocrinology, 159(6), 2324-2336. doi: 10.1210/en.2018-00057 Journal - Research Article

Macari, S., Sharma, L. A., Wyatt, A., Maíra da Silva, J., Dias, G. J., Silva, T. A., … Grattan, D. R. (2018). Lactation induces increases in the RANK/RANKL/OPG system in maxillary bone. Bone, 110, 160-169. doi: 10.1016/j.bone.2018.01.032 Journal - Research Article

Manning, P. J., Grattan, D., Merriman, T., Manning, T., Williams, S., & Sutherland, W. (2018). Pharmaceutical interventions for weight-loss maintenance: No effect from cabergoline. International Journal of Obesity, 42, 1871-1879. doi: 10.1038/s41366-018-0165-3 Journal - Research Article

McEwen, H. J. L., Cognard, E., Ladyman, S. R., Khant-Aung, Z., Tups, A., Shepherd, P. R., & Grattan, D. R. (2018). Feeding and GLP-1 receptor activation stabilize beta-catenin in specific hypothalamic nuclei in male rats. Journal of Neuroendocrinology, 30(6), e12607, 1-10. doi: 10.1111/jne.12607 Journal - Research Article

Yip, S. H., York, J., Hyland, B., Bunn, S. J., & Grattan, D. R. (2018). Incomplete concordance of dopamine transporter Cre (DAT^IREScre)-mediated recombination and tyrosine hydroxylase immunoreactivity in the mouse forebrain. Journal of Chemical Neuroanatomy, 90, 40-48. doi: 10.1016/j.jchemneu.2017.12.002 Journal - Research Article

Augustine, R. A., Ladyman, S. R., Bouwer, G. T., Alyousif, Y., Sapsford, T. J., Scott, V., Kokay, I. C., Grattan, D. R., & Brown, C. H. (2017). Prolactin regulation of oxytocin neurone activity in pregnancy and lactation. Journal of Physiology, 595(11), 3591-3605. doi: 10.1113/jp273712 Journal - Research Article

Barad, Z., Grattan, D. R., & Leitch, B. (2017). NMDA receptor expression in the thalamus of the stargazer model of absence epilepsy. Scientific Reports, 7, 42926. doi: 10.1038/srep42926 Journal - Research Article

Booker, C. S., & Grattan, D. R. (2017). IL1R9 is evolutionarily related to IL18BP and may function as an IL-18 receptor. Journal of Immunology, 198(1), 270-278. doi: 10.4049/jimmunol.1500648 Journal - Research Article

Brown, R. S. E., Aoki, M., Ladyman, S. R., Phillipps, H. R., Wyatt, A., Boehm, U., & Grattan, D. R. (2017). Prolactin action in the medial preoptic area is necessary for postpartum maternal nursing behavior. PNAS, 114(40), 10779-10784. doi: 10.1073/pnas.1708025114 Journal - Research Article

Gustafson, P., Bunn, S. J., & Grattan, D. R. (2017). The role of prolactin in the suppression of Crh mRNA expression during pregnancy and lactation in the mouse. Journal of Neuroendocrinology, 29(9), e12511. doi: 10.1111/jne.12511 Journal - Research Article

Gustafson, P., Kokay, I., Sapsford, T., Bunn, S., & Grattan, D. (2017). Prolactin regulation of the HPA axis is not mediated by a direct action upon CRH neurons: Evidence from the rat and mouse. Brain Structure & Function, 222(7), 3191-3204. doi: 10.1007/s00429-017-1395-1 Journal - Research Article

Kirk, S. E., Xie, T. Y., Steyn, F. J., Grattan, D. R., & Bunn, S. J. (2017). Restraint stress increases prolactin-mediated phosphorylation of signal transducer and activator of transcription 5 in the hypothalamus and adrenal cortex in the male mouse. Journal of Neuroendocrinology, 29(6), 1-9. doi: 10.1111/jne.12477 Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2017). Region-specific suppression of hypothalamic responses to insulin to adapt to elevated maternal insulin secretion during pregnancy. Endocrinology, 158(12), 4257-4269. doi: 10.1210/en.2017-00600 Journal - Research Article

Ladyman, S. R., MacLeod, M. A., Khant Aung, Z., Knowles, P., Phillipps, H. R., Brown, R. S. E., & Grattan, D. R. (2017). Prolactin receptors in Rip-cre cells, but not in AgRP neurons, are involved in energy homeostasis. Journal of Neuroendocrinology, 29(10), e12474. doi: 10.1111/jne.12474 Journal - Research Article

Rizwan, M. Z., Mehlitz, S., Grattan, D. R., & Tups, A. (2017). Temporal and regional onset of leptin resistance in diet-induced obese mice. Journal of Neuroendocrinology, 29(10), e12481. doi: 10.1111/jne.12481 Journal - Research Article

Alqaisi, K. M., Lamare, M. D., Grattan, D. R., Damsteegt, E. L., Schneider, W. J., & Lokman, P. M. (2016). A comparative study of vitellogenesis in Echinodermata: Lessons from the sea star. Comparative Biochemistry & Physiology Part A, 198, 72-86. doi: 10.1016/j.cbpa.2016.04.013 Journal - Research Article

Augustine, R. A., Bouwer, G. T., Seymour, A. J., Grattan, D. R., & Brown, C. H. (2016). Reproductive regulation of gene expression in the hypothalamic supraoptic and paraventricular nuclei. Journal of Neuroendocrinology, 28(4). doi: 10.1111/jne.12350 Journal - Research Article

Brown, R. S. E., Kokay, I. C., Phillipps, H. R., Yip, S. H., Gustafson, P., Wyatt, A., Larsen, C. M., Knowles, P., Ladyman, S. R., LeTissier, P., & Grattan, D. R. (2016). Conditional deletion of the prolactin receptor reveals functional subpopulations of dopamine neurons in the arcuate nucleus of the hypothalamus. Journal of Neuroscience, 36(35), 9173-9185. doi: 10.1523/jneurosci.1471-16.2016 Journal - Research Article

Brown, R. S. E., Wyatt, A. K., Herbison, R. E., Knowles, P. J., Ladyman, S. R., Binart, N., … Grattan, D. R. (2016). Prolactin transport into mouse brain is independent of prolactin receptor. FASEB Journal, 30(2), 1002-1010. doi: 10.1096/fj.15-276519 Journal - Research Article

Kim, D. W., Glendining, K. A., Grattan, D. R., & Jasoni, C. L. (2016). Maternal obesity in the mouse compromises the blood-brain barrier in the arcuate nucleus of offspring. Endocrinology, 157(6), 2229-2242. doi: 10.1210/en.2016-1014 Journal - Research Article

Kim, D. W., Glendining, K. A., Grattan, D. R., & Jasoni, C. L. (2016). Maternal obesity leads to increased proliferation and numbers of astrocytes in the developing fetal and neonatal mouse hypothalamus. International Journal of Developmental Neuroscience, 53, 18-25. doi: 10.1016/j.ijdevneu.2016.06.005 Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2016). Central effects of leptin on glucose homeostasis are modified during pregnancy in the rat. Journal of Neuroendocrinology, 28(10). doi: 10.1111/jne.12431 Journal - Research Article

Ladyman, S. R., Augustine, R. A., Scherf, E., Phillipps, H. R., Brown, C. H., & Grattan, D. R. (2016). Attenuated hypothalamic responses to α-melanocyte stimulating hormone during pregnancy in the rat. Journal of Physiology, 594(4), 1087-1101. doi: 10.1113/jp271605 Journal - Research Article

Macari, S., Ajay Sharma, L., Wyatt, A., Knowles, P., Szawka, R. E., Garlet, G. P., Grattan, D. R., Dias, G. J., & Silva, T. A. (2016). Osteoprotective effects of estrogen in the maxillary bone depend on ERα. Journal of Dental Research, 95(6), 689-696. doi: 10.1177/0022034516633154 Journal - Research Article

McEwen, H. J. L., Inglis, M. A., Quennell, J. H., Grattan, D. R., & Anderson, G. M. (2016). Deletion of suppressor of cytokine signaling 3 from forebrain neurons delays infertility and onset of hypothalamic leptin resistance in response to a high caloric diet. Journal of Neuroscience, 36(27), 7142-7153. doi: 10.1523/jneurosci.2714-14.2016 Journal - Research Article

Vergara-Castañeda, E., Grattan, D. R., Pasantes-Morales, H., Pérez-Domínguez, M., Cabrera-Reyes, E. A., Morales, T., & Cerbón, M. (2016). Prolactin mediates neuroprotection against excitotoxicity in primary cell cultures of hippocampal neurons via its receptor. Brain Research, 1636, 193-199. doi: 10.1016/j.brainres.2016.02.011 Journal - Research Article

Grattan, D. R., & Le Tissier, P. (2015). Hypothalamic control of prolactin secretion, and the multiple reproductive functions of prolactin. In T. M. Plant & A. J. Zeleznik (Eds.), Knobil and Neill's Physiology of reproduction (Vol. 1). (4th ed.) (pp. 469-526). Elsevier. doi: 10.1016/B978-0-12-397175-3.00012-0 Chapter in Book - Research

Brown, R. S. E., Herbison, A. E., & Grattan, D. R. (2015). Effects of prolactin and lactation on A15 dopamine neurons in the rostral preoptic area of female mice. Journal of Neuroendocrinology, 27(9), 708-717. doi: 10.1111/jne.12297 Journal - Research Article

Grattan, D. R. (2015). 60 years of neuroendocrinology: The hypothalamo-prolactin axis. Journal of Endocrinology, 226(2), T101-T122. doi: 10.1530/joe-15-0213 Journal - Research Article

Araujo-Lopes, R., Crampton, J. R., Aquino, N. S. S., Miranda, R. M., Kokay, I. C., Reis, A. M., … Grattan, D. R., & Szawka, R. E. (2014). Prolactin regulates kisspeptin neurons in the arcuate nucleus to suppress LH secretion in female rats. Endocrinology, 155(3), 1010-1020. doi: 10.1210/en.2013-1889 Journal - Research Article

Booker, C. S., & Grattan, D. R. (2014). Identification of a truncated splice variant of IL-18 receptor alpha in the human and rat, with evidence of wider evolutionary conservation. PeerJ, 2, e560. doi: 10.7717/peerj.560 Journal - Research Article

Brown, R. C., McLay-Cooke, R. T., Richardson, S. L., Williams, S. M., Grattan, D. R., & Chisholm, A. W.-A. H. (2014). Appetite response among those susceptible or resistant to obesity. International Journal of Endocrinology, 2014, 512013. doi: 10.1155/2014/512013 Journal - Research Article

Brown, R. S. E., Herbison, A. E., & Grattan, D. R. (2014). Prolactin regulation of kisspeptin neurones in the mouse brain and its role in the lactation-induced suppression of kisspeptin expression. Journal of Neuroendocrinology, 26(12), 898-908. doi: 10.1111/jne.12223 Journal - Research Article

Kim, D. W., Young, S. L., Grattan, D. R., & Jasoni, C. L. (2014). Obesity during pregnancy disrupts placental morphology, cell proliferation, and inflammation in a sex-specific manner across gestation in the mouse. Biology of Reproduction, 90(6), 130. doi: 10.1095/biolreprod.113.117259 Journal - Research Article

Koch, C. E., Lowe, C., Legler, K., Benzler, J., Boucsein, A., Böttiger, G., Grattan, D. R., … Tups, A. (2014). Central adiponectin acutely improves glucose tolerance in male mice. Endocrinology, 155(5), 1806-1816. doi: 10.1210/en.2013-1734 Journal - Research Article

Liu, X., Brown, R. S. E., Herbison, A. E., & Grattan, D. R. (2014). Lactational anovulation in mice results from a selective loss of kisspeptin input to GnRH neurons. Endocrinology, 155(1), 193-203. doi: 10.1210/en.2013-1621 Journal - Research Article

Benzler, J., Andrews, Z. B., Pracht, C., Stöhr, S., Shepherd, P. R., Grattan, D. R., & Tups, A. (2013). Hypothalamic WNT signalling is impaired during obesity and reinstated by leptin treatment in male mice. Endocrinology, 154(12), 4737-4745. doi: 10.1210/en.2013-1746 Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2013). JAK-STAT and feeding. JAK-STAT, 2(2), e23675. doi: 10.4161/jkst.23675 Journal - Research Article

Phillipps, H. R., Ladyman, S. R., & Grattan, D. R. (2013). Maintained expression of genes associated with metabolism in the ventromedial hypothalamic nucleus despite development of leptin resistance during pregnancy in the rat. Physiological Reports, 1(6), e00162. doi: 10.1002/phy2.162 Journal - Research Article

Romanò, N., Yip, S. H., Hodson, D. J., Guillou, A., Parnaudeau, S., Kirk, S., … Bunn, S. J., Grattan, D. R., … Martin, A. O. (2013). Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release. Journal of Neuroscience, 33(10), 4424-4433. doi: 10.1523/jneurosci.4415-12.2013 Journal - Research Article

Adler, E. S., Hollis, J. H., Clarke, I. J., Grattan, D. R., & Oldfield, B. J. (2012). Neurochemical characterization and sexual dimorphism of projections from the brain to abdominal and subcutaneous white adipose tissue in the rat. Journal of Neuroscience, 32(45), 15913-15921. doi: 10.1523/jneurosci.2591-12.2012 Journal - Research Article

Benzler, J., Ganjam, G. K., Krüger, M., Pinkenburg, O., Kutschke, M., Stöhr, S., … Grattan, D. R., & Tups, A. (2012). Hypothalamic glycogen synthase kinase 3β has a central role in the regulation of food intake and glucose metabolism. Biochemical Journal, 447(1), 175-184. doi: 10.1042/bj20120834 Journal - Research Article

Brown, R. S. E., Piet, R., Herbison, A. E., & Grattan, D. R. (2012). Differential actions of prolactin on electrical activity and intracellular signal transduction in hypothalamic neurons. Endocrinology, 153(5), 2375-2384. doi: 10.1210/en.2011-2005 Journal - Research Article

Ladyman, S. R., Fieldwick, D. M., & Grattan, D. R. (2012). Suppression of leptin-induced hypothalamic JAK/STAT signaling and feeding response during pregnancy in the mouse. Reproduction, 144(1), 83-90. doi: 10.1530/rep-12-0112 Journal - Research Article

Larsen, C. M., & Grattan, D. R. (2012). Prolactin, neurogenesis, and maternal behaviors. Brain, Behavior & Immunity, 26(2), 201-209. doi: 10.1016/j.bbi.2011.07.233 Journal - Research Article

Li, Q., Li, N., Le Tissier, P., Grattan, D. R., & Kerman, K. (2012). Miniaturized electrochemical immunosensor for label-free detection of growth hormone. Electroanalysis, 24(6), 1272-1276. doi: 10.1002/elan.201200074 Journal - Research Article

Sapsford, T. J., Kokay, I. C., Östberg, L., Bridges, R. S., & Grattan, D. R. (2012). Differential sensitivity of specific neuronal populations of the rat hypothalamus to prolactin action. Journal of Comparative Neurology, 520(5), 1062-1077. doi: 10.1002/cne.22775 Journal - Research Article

Yip, S. H., Eguchi, R., Grattan, D. R., & Bunn, S. J. (2012). Prolactin signalling in the mouse hypothalamus is primarily mediated by signal transducer and activator of transcription factor 5b but not 5a. Journal of Neuroendocrinology, 24(12), 1484-1491. doi: 10.1111/j.1365-2826.2012.02357.x Journal - Research Article

Larsen, C. M., & Grattan, D. R. (2010). Exposure to female pheromones during pregnancy causes postpartum anxiety in mice. In G. Litwack (Ed.), Pheromones: Vitamins & Hormones (Vol. 83). (pp. 137-149). Amsterdam: Academic Press. doi: 10.1016/S0083-6729(10)83005-5 Chapter in Book - Research

Grattan, D. R., & Bridges, R. S. (2009). Prolactin actions in the brain. In D. W. Pfaff, A. P. Arnold, A. M. Etgen, S. E. Fahrbach & R. T. Rubin (Eds.), Hormones, brain and behavior (Vol. 4). (2nd ed.) (pp. 2471-2503). San Diego, CA: Academic Press. Chapter in Book - Research

Freeman, M. E., Grattan, D. R., & Houpt, T. A. (2008). The hypothalamus. In P. M. Conn (Ed.), Neuroscience in medicine. (3rd ed.) (pp. 301-358). Totowna, NJ: Humana Press. Chapter in Book - Research

Woodside, B., Augustine, R. A., Ladyman, S. R., Naef, L., & Grattan, D. R. (2008). Role of prolactin in the metabolic adaptations to pregnancy and lactation. In R. S. Bridges (Ed.), Neurobiology of the parental brain. (pp. 249-267). London: Academic Press. Chapter in Book - Research

Grattan, D. R., & Möderscheim, T. A. E. (2006). Interaction of growth hormone and prolactin in brain circuits. In F. J. Nyberg (Ed.), The somatotrophic axis in brain function. (pp. 111-123). Amsterdam: Elsevier. Chapter in Book - Research

Grattan, D. R. (2001). The actions of prolactin in the brain during pregnancy and lactation. In J. A. Russell, A. J. Douglas, R. J. Windle & C. D. Ingram (Eds.), Progress in Brain Research. (pp. 153-171). London: Elsevier. Chapter in Book - Research

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