Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Grattan Laboratory

Research interests

My group within the Centre for Neuroendocrinology is interested in the neuroendocrine functions of the hormone prolactin, and in particular, the role of prolactin in the neuroendocrine and neurobiological adaptations of the maternal brain.

Specific interests include the control of appetite and body weight during pregnancy and obesity, plasticity in oxytocin neurons during late pregnancy and lactation, and role of prolactin in changes in mood and behaviour in the post-partum period.

Clinical conditions

  • Hyperprolactinaemia
  • Infertility
  • Post-partum anxiety
  • Post-partum depression

List of publications for Dave Grattan (Google Scholar)

Grattan Laboratory staff & students

Jenny Clarkson_webJenny Clarkson, Research Fellow
Neural circuits required for maternal adaptation to pregnancy

Teodora Georgescu_webTeodora Georgescu, Postdoctoral Fellow
Cellular actions of prolactin on neurons

Eleni Hackwell_webEleni Hackwell, PhD Student
The role of prolactin in lactational infertility

Zin Khant Aung_webZin Khant-Aung, Assistant Research Fellow
Hormonal regulation of metabolism

Pene Knowles_webPene Knowles, Research Technician
Prolactin neuroendocrinology

Ilona Kokay_webIlona Kokay, Honorary Research Fellow
Prolactin receptor expression in the brain

Sharon Ladyman_webSharon Ladyman, Senior Research Fellow
Regulation of energy homeostasis during pregnancy

Chantelle Murrell_webChantelle Murrell, PhD student

Holly Phillipps_webHollian Phillipps, Postdoctoral Fellow
Prolactin action in adult neurogenesis

Yeri Rim_webYeri Rim, Assistant Research Fellow

Mo Rizwan_webMohammed Rizwan, Postdoctoral Fellow
Hypothalamic regulation of bodyweight and glucose metabolism

Kristina Smiley_webKristina Smiley, Postdoctoral Fellow
Neuroendocrine regulation of paternal behaviour

Judith Swart_webJudith Swart, PhD Student
Involvement of the reward circuitry in prolactin’s regulation of maternal behaviour

Joe Yip_webJoe Yip, Postdoctoral Fellow
Plasticity of neuroendocrine dopaminergic neurons and prolactin

Charlie Fang, Honours student

Matt Gillet, Honours student

Visit Our people for an alphabetical list of all Centre for Neuroendocrinology staff.


Ladyman, S. R., Carter, K. M., Gillett, M. L., Khant Aung, Z., & Grattan, D. R. (2021). A reduction in voluntary physical activity in early pregnancy in mice is mediated by prolactin. eLIFE, 10, e62260. doi: 10.7554/eLife.62260

Porteous, R., Haden, P., Hackwell, E. C. R., Singline, A. J., Herde, M. K., Desai, R., … Grattan, D. R., & Herbison, A. E. (2021). Reformulation of PULSAR for analysis of pulsatile LH secretion and a revised model of estrogen negative feedback in mice. Endocrinology, 162(11). doi: 10.1210/endocr/bqab165

Swart, J. M., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2021). Changes in maternal motivation across reproductive states in mice: A role for prolactin receptor activation on GABA neurons. Hormones & Behavior, 135, 105041. doi: 10.1016/j.yhbeh.2021.105041

Nair, B. B., Khant Aung, Z., Porteous, R., Prescott, M., Glendining, K. A., Jenkins, D. E., Augustine, R. A., … Yip, S. H., Bouwer, G. T., Brown, C. H., Jasoni, C. L., Campbell, R. E., Bunn, S. J., Anderson, G. M., Grattan, D. R., Herbison, A. E., & Iremonger, K. J. (2021). Impact of chronic variable stress on neuroendocrine hypothalamus and pituitary in male and female C57BL/6J mice. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.12972

Grattan, D. R., & Andrews, Z. B. (2021). Insulin as a neuroendocrine hormone. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.12966