My group within the Centre for Neuroendocrinology is interested in the neuroendocrine functions of the hormone prolactin, and in particular, the role of prolactin in the neuroendocrine and neurobiological adaptations of the maternal brain.
Specific interests include the control of appetite and body weight during pregnancy and obesity, plasticity in oxytocin neurons during late pregnancy and lactation, and role of prolactin in changes in mood and behaviour in the post-partum period.
- Post-partum anxiety
- Post-partum depression
Grattan Laboratory staff & students
Jenny Clarkson, Research Fellow
Neural circuits required for maternal adaptation to pregnancy
Teodora Georgescu, Scientific Officer
Cellular actions of prolactin on neurons
Matt Gillett, PhD student
Zin Khant-Aung, Assistant Research Fellow
Hormonal regulation of metabolism
Pene Knowles, Research Technician
Ilona Kokay, Honorary Research Fellow
Prolactin receptor expression in the brain
Sharon Ladyman, Senior Research Fellow
Regulation of energy homeostasis during pregnancy
Chantelle Murrell, PhD student
Hollian Phillipps, Research Fellow
Prolactin action in adult neurogenesis
Mohammed Rizwan, Research Fellow
Hypothalamic regulation of bodyweight and glucose metabolism
Joe Yip, Research Fellow
Plasticity of neuroendocrine dopaminergic neurons and prolactin
Visit Our people for an alphabetical list of all Centre for Neuroendocrinology staff.
Hassan, M., Grattan, D. R., & Leitch, B. (2023). Developmental inhibitory changes in the primary somatosensory cortex of the stargazer mouse model of absence epilepsy. Biomolecules, 13, 186. doi: 10.3390/biom13010186
Young, C., Grattan, D., & Ladyman, S. (2022). Effect of the Polynesian-specific CREBRF gene variant on lactogenic activity during mouse pregnancy. Proceedings of the joint ESA-SRB-APEG-NZSE Annual Scientific Meeting. 139. Retrieved from https://www.esa-srb-apeg-nzse.org
Smiley, K. O., Brown, R. S. E., & Grattan, D. R. (2022). Prolactin action is necessary for parental behavior in male mice. Journal of Neuroscience. Advance online publication. doi: 10.1523/jneurosci.0558-22.2022
Khant Aung, Z., Kado, E., Young, C., Grattan, D. R., & Ladyman, S. R. (2022, August). Protective role of a Polynesian-specific variant of CREBRF gene against gestational diabetes mellitus (GDM): Mouse model. Verbal presentation at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
Grattan, D. R. (2022, August). Hypothalamic Wnt/b-catenin signalling is required for normal metabolic homeostasis. Verbal presentation at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.