I am interested in defining how the gonadotrophin releasing hormone (GnRH) neurons, well established as the ultimate downstream regulators of the central control of reproductive function, are regulated by the multitude of external and internal cues necessary for successful fertility.
At the Centre for Neuroendocrinology I am investigating the synaptic regulation of GnRH neurons, with particular emphasis on the innervation to their lengthy dendrites, through a variety of morphological imaging and transgenic mouse model approaches. In addition to understanding the regulation of normal fertility, I am also interested in addressing the central neuroendocrine abnormalities of polycystic ovarian syndrome (PCOS), the leading cause of infertility in women.
Current and proposed projects:
Exploring the neuroendocrine mechanisms of PCOS
Mechanisms of pulse generation in the GnRH neuronal network
Steroid induced structural plasticity within the GnRH neuronal network
Prescott, M., Watanabe, Y., Ruddenklau, A., Fisher, L., Jasoni, C. L., & Campbell, R. E. (2023). Kisspeptin neuron projections and expression patterns are unaltered in prenatally androgenized female mice modeling PCOS. Journal of the Endocrine Society, 7(Suppl. 1), (pp. A649-A650). doi: 10.1210/jendso/bvad114.1213
Conference Contribution - Published proceedings: Abstract
Ruddenklau, A., Glendining, K., Prescott, M., & Campbell, R. E. (2023). Validation of a new custom polyclonal progesterone receptor antibody for immunohistochemistry in the female mouse brain. Journal of the Endocrine Society, bvad113. Advance online publication. doi: 10.1210/jendso/bvad113
Journal - Research Article
Emanuel, R. H. K., Docherty, P. D., Lunt, H., & Campbell, R. E. (2023). Comparing literature- and subreddit-derived laboratory values in polycystic ovary syndrome (PCOS): Validation of clinical data posted on PCOS Reddit forums. JMIR Formative Research, 7, e44810. doi: 10.2196/44810
Journal - Research Article
Watanabe, Y., Fisher, L., Campbell, R. E., & Jasoni, C. L. (2023). Defining potential targets of prenatal androgen excess: Expression analysis of androgen receptor on hypothalamic neurons in the fetal female mouse brain. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13302
Journal - Research Article
Decourt, C., Watanabe, Y., Evans, M. C., Inglis, M. A., Fisher, L. C., Jasoni, C. L., Campbell, R. E., & Anderson, G. M. (2023). Deletion of androgen receptors from kisspeptin neurons prevents PCOS features in a letrozole mouse model. Endocrinology, bqad077. Advance online publication. doi: 10.1210/endocr/bqad077
Journal - Research Article
Donaldson, N. M., Prescott, M., Ruddenklau, A., Campbell, R. E., & Desroziers, E. (2023). Maternal androgen excess significantly impairs sexual behavior in male and female mouse offspring: Perspective for a biological origin of sexual dysfunction in PCOS. Frontiers in Endocrinology, 14, 1116482. doi: 10.3389/fendo.2023.1116482
Journal - Research Article
Glendining, K. A., & Campbell, R. E. (2023). Recent advances in emerging PCOS therapies. Current Opinion in Pharmacology, 68, 102345. doi: 10.1016/j.coph.2022.102345
Journal - Research Other
Lissaman, A. C., Girling, J. E., Cree, L. M., Campbell, R. E., & Ponnampalam, A. P. (2023). Androgen signalling in the ovaries and endometrium. Molecular Human Reproduction. Advance online publication. doi: 10.1093/molehr/gaad017
Journal - Research Other
Abbasi, M., Perkinson, M. R., Seymour, A. J., Piet, R., Campbell, R. E., Iremonger, K. J., & Brown, C. H. (2022). Local kisspeptin excitation of rat oxytocin neurones in late pregnancy. Journal of Physiology, 600(7), 1753-1770. doi: 10.1113/jp282531
Journal - Research Article
Coyle, C. S., Prescott, M., Handelsman, D. J., Walters, K. A., & Campbell, R. E. (2022). Chronic androgen excess in female mice does not impact luteinizing hormone pulse frequency or putative GABAergic inputs to GnRH neurons. Journal of Neuroendocrinology, 34, e13110. doi: 10.1111/jne.13110
Journal - Research Article
Emanuel, R. H. K., Roberts, J., Docherty, P. D., Lunt, H., Campbell, R. E., & Möller, K. (2022). A review of the hormones involved in the endocrine dysfunctions of polycystic ovary syndrome and their interactions. Frontiers in Endocrinology, 13, 1017468. doi: 10.3389/fendo.2022.1017468
Journal - Research Article
Evans, M. C., Campbell, R. E., & Anderson, G. M. (2022). Physiological regulation of leptin as an integrative signal of reproductive readiness [Review]. Current Opinion in Pharmacology, 67, 102321. doi: 10.1016/j.coph.2022.102321
Journal - Research Article
Jamieson, B. B., Moore, A. M., Lohr, D. B., Thomas, S. X., Coolen, L. M., Lehman, M. N., Campbell, R. E., & Piet, R. (2022). Prenatal androgen treatment impairs the suprachiasmatic nucleus arginine-vasopressin to kisspeptin neuron circuit in female mice. Frontiers in Endocrinology, 13, 951344. doi: 10.3389/fendo.2022.951344
Journal - Research Article
Khant Aung, Z., Masih, R. R., Desroziers, E., Campbell, R. E., & Brown, R. S. E. (2022). Enhanced pup retrieval behaviour in a mouse model of polycystic ovary syndrome. Journal of Neuroendocrinology, 34, e13206. doi: 10.1111/jne.13206
Journal - Research Article
Silva, M. S. B., & Campbell, R. E. (2022). Polycystic Ovary Syndrome and the neuroendocrine consequences of androgen excess. Comprehensive Physiology, 12, 3347-3369. doi: 10.1002/cphy.c210025
Journal - Research Article
Campbell, R. E., Coolen, L. M., Hoffman, G. E., & Hrabovszky, E. (2022). Highlights of neuroanatomical discoveries of the mammalian gonadotropin-releasing hormone system. Journal of Neuroendocrinology, e13115. Advance online publication. doi: 10.1111/jne.13115
Journal - Research Other
McCartney, C. R., Campbell, R. E., Marshall, J. C., & Moenter, S. M. (2022). The role of gonadotropin-releasing hormone neurons in polycystic ovary syndrome [Invited]. Journal of Neuroendocrinology, 34, e13093. doi: 10.1111/jne.13093
Journal - Research Other
Seeger-Armbruster, S., Ahmad Zamri, A., Wang, M., Campbell, R. E., & Hyland, B. I. (2022). Thalamic paraventricular nucleus: Bridging homeostatic and reward pathways in the control of feeding. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 96). Retrieved from https://www.queenstownresearchweek.org
Conference Contribution - Published proceedings: Abstract
Sugrue, V. J., Garratt, M., Campbell, R. E., & Hore, T. A. (2022). Androgens and the epigenetic clock. Proceedings of the joint ESA-SRB-APEG-NZSE Annual Scientific Meeting. 13. Retrieved from https://www.esa-srb-apeg-nzse.org
Conference Contribution - Published proceedings: Abstract
Elenis, E., Desroziers, E., Persson, S., Sundström Poromaa, I., & Campbell, R. E. (2021). Early initiation of anti-androgen treatment is associated with increased probability of spontaneous conception leading to childbirth in women with polycystic ovary syndrome: A population-based multiregistry cohort study in Sweden. Human Reproduction, 36(5), 1427-1435. doi: 10.1093/humrep/deaa357
Journal - Research Article
Jamieson, B. B., Bouwer, G. T., Campbell, R. E., & Piet, R. (2021). Estrous cycle plasticity in the central clock output to kisspeptin neurons: Implications for the preovulatory surge. Endocrinology, 162(6), 1-20. doi: 10.1210/endocr/bqab071
Journal - Research Article
Nair, B. B., Khant Aung, Z., Porteous, R., Prescott, M., Glendining, K. A., Jenkins, D. E., Augustine, R. A., Silva, M. S. B., Yip, S. H., Bouwer, G. T., Brown, C. H., Jasoni, C. L., Campbell, R. E., Bunn, S. J., Anderson, G. M., Grattan, D. R., Herbison, A. E., & Iremonger, K. J. (2021). Impact of chronic variable stress on neuroendocrine hypothalamus and pituitary in male and female C57BL/6J mice. Journal of Neuroendocrinology, 33, e12972. doi: 10.1111/jne.12972
Journal - Research Article
Sati, A., Prescott, M., Holland, S., Jasoni, C. L., Desroziers, E., & Campbell, R. E. (2021). Morphological evidence indicate a role for microglia in shaping the polycystic ovary syndrome (PCOS)-like brain. Journal of Neuroendocrinology, 33, e12999. doi: 10.1111/jne.12999
Journal - Research Article
Sucquart, I. E., Nagarkar, R., Edwards, M. C., Paris, V. R., Aflatounian, A., Bertoldo, M. J., Campbell, R. E., … Walters, K. A. (2021). Neurokinin 3 receptor antagonism ameliorates key metabolic features in a hyperandrogenic PCOS mouse model. Endocrinology, 162(5), 1-15. doi: 10.1210/endocr/bqab020
Journal - Research Article
Watanabe, Y., Prescott, M., Campbell, R. E., & Jasoni, C. L. (2021). Prenatal androgenization causes expression changes of progesterone and androgen receptor mRNAs in the arcuate nucleus of female mice across development. Journal of Neuroendocrinology, 33, e13058. doi: 10.1111/jne.13058
Journal - Research Article
Sati, A., Prescott, M., Jasoni, C. L., Desroziers, E., & Campbell, R. E. (2021). The role of microglia in the polycystic ovary syndrome (PCOS)-like brain. Journal of the Endocrine Society, 5(Suppl. 1), (pp. A556). doi: 10.1210/jendso/bvab048.1133
Conference Contribution - Published proceedings: Abstract
Coutinho, E. A., Prescott, M., Hessler, S., Marshall, C. J., Herbison, A. E., & Campbell, R. E. (2020). Activation of a classic hunger circuit slows luteinizing hormone pulsatility. Neuroendocrinology, 110(7-8), 671-687. doi: 10.1159/000504225
Journal - Research Article
Marshall, C. J., Prescott, M., & Campbell, R. E. (2020). Investigating the NPY/AgRP/GABA to GnRH neuron circuit in prenatally androgenized PCOS-like mice. Journal of the Endocrine Society, 4(11), bvaa129. doi: 10.1210/jendso/bvaa129
Journal - Research Article
Stener-Victorin, E., Padmanabhan, V., Walters, K. A., Campbell, R. E., Benrick, A., Giacobini, P., … Abbott, D. H. (2020). Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome. Endocrine Reviews, 41, 538-576. doi: 10.1210/endrev/bnaa010
Journal - Research Article
McCartney, C. R., & Campbell, R. E. (2020). Abnormal GnRH pulsatility in polycystic ovary syndrome: Recent insights. Current Opinion in Endocrine & Metabolic Research, 12, 78-84. doi: 10.1016/j.coemr.2020.04.005
Journal - Research Other
Gordon, C., Campbell, R., & Ranta, A. (2019). Impact of the national public 'FAST' campaigns. New Zealand Medical Journal, 132(1507), 48-56. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Article
Holland, S., Prescott, M., Pankhurst, M., & Campbell, R. E. (2019). The influence of maternal androgen excess on the male reproductive axis. Scientific Reports, 9, 18908. doi: 10.1038/s41598-019-55436-9
Journal - Research Article
Silva, M. S. B., Desroziers, E., Hessler, S., Prescott, M., Coyle, C., Herbison, A. E., & Campbell, R. E. (2019). Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndrome. EBioMedicine, 44, 582-596. doi: 10.1016/j.ebiom.2019.05.065
Journal - Research Article
Coyle, C., & Campbell, R. E. (2019). Pathological pulses in PCOS. Molecular & Cellular Endocrinology, 498, 110561. doi: 10.1016/j.mce.2019.110561
Journal - Research Other
Ruddenklau, A., & Campbell, R. E. (2019). Neuroendocrine impairments of polycystic ovary syndrome. Endocrinology, 160(10), 2230-2242. doi: 10.1210/en.2019-00428
Journal - Research Other
Coutinho, E., Prescott, M., Marshall, C., Hessler, S., Herbison, A., & Campbell, R. (2019). Functional role of arcuate nucleus NPY/AgRP neurons in the GnRH circuit regulating LH secretion. Journal of the Endocrine Society, 3(Suppl. 1), SUN-LB083. doi: 10.1210/js.2019-SUN-LB083
Conference Contribution - Published proceedings: Abstract
Holland, S., Prescott, M., Desroziers, E., & Campbell, R. (2019). Elucidating the effect of prenatal androgen excess on male reproductive function and metabolism. New Zealand Medical Journal, 132(1499), (pp. 88). Retrieved from https://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Jamieson, B. B., Campbell, R. E., & Piet, R. (2019). Projections of suprachiasmatic nucleus vasopressin neurons regulate preoptic kisspeptin neuron electrical activity. Proceedings of the Society for Neuroscience Annual Meeting. 673.09/N39. SfN. Retrieved from https://www.sfn.org
Conference Contribution - Published proceedings: Abstract
Jamieson, B., Bouwer, G., Campbell, R., & Piet, R. (2019). Suprachiasmatic vasopressin neurons alter the activity of preoptic kisspeptin neurons in female mice. Brain & Neuroscience Advances, 3, PM100. doi: 10.1177/2398212819855490
Conference Contribution - Published proceedings: Abstract
Marshall, C., Coutinho, E., & Campbell, R. (2019). Examining alterations to arcuate nucleus NPY neurons and their neural projections in a mouse model of PCOS. Journal of the Endocrine Society, 3(Suppl. 1), SAT-413. doi: 10.1210/js.2019-SAT-413
Conference Contribution - Published proceedings: Abstract
Watanabe, Y., Prescott, M., Fisher, L. C., Campbell, R. E., Anderson, G. M., & Jasoni, C. L. (2019). Investigating changes in androgen and progesterone receptor expression in the aetiology of PNA-induced polycystic ovary syndrome. Proceedings of the Queenstown Molecular Biology (QMB) Meetings. [Abstract]
Conference Contribution - Published proceedings: Abstract
Campbell, R. E. (2018). Morphology of the adult GnRH neuron. In A. E. Herbison & T. M. Plant (Eds.), The GnRHS neuron and its control. (pp. 121-142). Hoboken, NJ: Wiley Blackwell. doi: 10.1002/9781119233275
Chapter in Book - Research
Moore, A. M., Abbott, G., Mair, J., Prescott, M., & Campbell, R. E. (2018). Mapping GABA and glutamate inputs to gonadotrophin-releasing hormone neurones in male and female mice. Journal of Neuroendocrinology, 30, e12657. doi: 10.1111/jne.12657
Journal - Research Article
Moore, A. M., Prescott, M., Czieselsky, K., Desroziers, E., Yip, S. H., Campbell, R. E., & Herbison, A. E. (2018). Synaptic innervation of the GnRH neuron distal dendron in female mice. Endocrinology, 159(9), 3200-3208. doi: 10.1210/en.2018-00505
Journal - Research Article
Silva, M. S. B., Prescott, M., & Campbell, R. E. (2018). Ontogeny and reversal of brain circuit abnormalities in a preclinical model of PCOS. JCI Insight, 3(7), e399405. doi: 10.1172/jci.insight.99405
Journal - Research Article
Augustine, R. A., Seymour, A. J., Campbell, R. E., Grattan, D. R., & Brown, C. H. (2018). Integrative neurohumoral regulation of oxytocin neurone activity in pregnancy and lactation. Journal of Neuroendocrinology, 30(8), e12569. doi: 10.1111/jne.12569
Journal - Research Other
Walters, K. A., Gilchrist, R. B., Ledger, W. L., Teede, H. J., Handelsman, D. J., & Campbell, R. E. (2018). New perspectives on the pathogenesis of PCOS: Neuroendocrine origins. Trends in Endocrinology & Metabolism, 29(12), 841-852. doi: 10.1016/j.tem.2018.08.005
Journal - Research Other
Campbell, R. (2018). Dissecting the role of specific brain circuits in polycystic ovary syndrome (PCOS). Clinical Endocrinology, 89(Suppl. 1), (pp. 30-31). doi: 10.1111/cen.13727
Conference Contribution - Published proceedings: Abstract
Campbell, R. E. (2018). Dissecting the neuroendocrine dysfunction of polycystic ovary syndrome. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 29). Retrieved from http://www.icn2018.org/
Conference Contribution - Published proceedings: Abstract
Campbell, R. E. (2018). Mechanisms of GnRH pulsatility: Lessons from PCOS. Endocrine Reviews, 39(2). [Abstract]
Conference Contribution - Published proceedings: Abstract
Coutinho, E., Prescott, M., Desroziers, E., Hessler, S., & Campbell, R. E. (2018). Activation of ARN AgRP/NPY neurons slows LH pulsality in control and PCOS mice. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 133). Retrieved from http://www.icn2018.org/
Conference Contribution - Published proceedings: Abstract
Desroziers, E., Coutinho, E., Prescott, M., Silva, M., Holland, S., & Campbell, R. E. (2018). The impact of chronic activation of arcuate GABA neurons on fertility. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 246). Retrieved from http://www.icn2018.org/
Conference Contribution - Published proceedings: Abstract
Desroziers, E., Prescott, M., & Campbell, R. E. (2018). Impaired sexual behaviour in a mouse model of PCOS. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 288-289). Retrieved from http://www.icn2018.org/
Conference Contribution - Published proceedings: Abstract
Jamieson, B., Bouwer, G., Campbell, R. E., & Piet, R. (2018). Suprachiasmatic vasopressin neurons project to preoptic kisspeptin neurons. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 244). Retrieved from http://www.icn2018.org/
Conference Contribution - Published proceedings: Abstract
Silva, M., Hessler, S., Prescott, M., Herbison, A. E., & Campbell, R. E. (2018). Selective activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion in mice. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 140). Retrieved from http://www.icn2018.org/
Conference Contribution - Published proceedings: Abstract
Kunovac-Kallak, T., Hellgren, C., Skalkidou, A., Sandelin-Francke, L., Ubhayasekhera, K., Bergquist, J., … Campbell, R. E., & Sundström Poromaa, I. (2017). Maternal and female fetal testosterone levels are associated with maternal age and gestational weight gain. European Journal of Endocrinology, 177, 379-388. doi: 10.1530/eje-17-0207
Journal - Research Article
Marshall, C. J., Desroziers, E., McLennan, T., & Campbell, R. E. (2017). Defining subpopulations of arcuate nucleus GABA neurons in male, female, and prenatally androgenized female mice. Neuroendocrinology, 105(2), 157-169. doi: 10.1159/000452105
Journal - Research Article
Moore, A. M., & Campbell, R. E. (2017). Polycystic ovary syndrome: Understanding the role of the brain. Frontiers in Neuroendocrinology, 46, 1-14. doi: 10.1016/j.yfrne.2017.05.002
Journal - Research Article
Seymour, A. J., Scott, V., Augustine, R. A., Bouwer, G. T., Campbell, R. E., & Brown, C. H. (2017). Development of an excitatory kisspeptin projection to the oxytocin system in late pregnancy. Journal of Physiology, 595(3), 825-838. doi: 10.1113/jp273051
Journal - Research Article
Coutinho, E. A., Desroziers, E., Prescott, M., & Campbell, R. E. (2017). Chemogenetic activation of arcuate neuropeptide Y neurons alters luteinising hormone secretion in mice. Endocrine Reviews, 38(3, Suppl.), SAT 447. [Abstract]
Conference Contribution - Published proceedings: Abstract
Marshall, C. J., & Campbell, R. E. (2017). Interrogation of arcuate nucleus GABAergic NPY neural circuitry in prenatally androgenised female mice. New Zealand Medical Journal, 130(1460), (pp. 95). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Nair, B., Khant Aung, Z., Porteous, R., Prescott, M., Ng, J., Yip, S., Augustine, R., Glendining, K., Bouwer, G., Kim, J., Jenkins, D., Silva, M., Brown, C., Campbell, R., Jasoni, C., Bunn, S., Anderson, G., Grattan, D., Herbison, A., & Iremonger, K. (2017). Impact of chronic stress on the neuroendocrine axis in the mouse. In B. Leitch (Ed.), Proceedings of the 35th International Australasian Winter Conference on Brain Research. (pp. 49). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr/index.html
Conference Contribution - Published proceedings: Abstract
Seymour, A. J., Campbell, R. E., & Brown, C. H. (2017). Development of an excitatory kisspeptin projection to the oxytocin system in late pregnancy. New Zealand Medical Journal, 130(1460), (pp. 98). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Cimino, I., Casoni, F., Liu, X., Messina, A., Parkash, J., Jamin, S. P., … Prescott, M., Campbell, R., Herbison, A. E., … Giacobini, P. (2016). Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion. Nature Communications, 7, 10055. doi: 10.1038/ncomms10055
Journal - Research Article
Czieselsky, K., Prescott, M., Porteous, R., Campos, P., Clarkson, J., Steyn, F. J., Campbell, R. E., & Herbison, A. E. (2016). Pulse and surge profiles of luteinizing hormone secretion in the mouse. Endocrinology, 157(12), 4794-4802. doi: 10.1210/en.2016-1351
Journal - Research Article
Moore, A. M., & Campbell, R. E. (2016). The neuroendocrine genesis of polycystic ovary syndrome: A role for arcuate nucleus GABA neurons. Journal of Steroid Biochemistry & Molecular Biology, 160, 106-117. doi: 10.1016/j.jsbmb.2015.10.002
Journal - Research Article
Marshall, C. J., Desroziers, E., & Campbell, R. E. (2016). Defining subpopulations of arcuate nucleus GABA neurons in male, female and prenatally androgenized female mice: A role for GABAergic NPY neurons in regulating fertility? Proceedings of the Society for Neuroscience 46th Annual Meeting. 339.02/TT8. SfN. Retrieved from https://www.sfn.org/
Conference Contribution - Published proceedings: Abstract
Silva, M. S., Prescott, M., & Campbell, R. (2016). Development of gabaergic altered brain wiring and plasticity in a mouse model of polycystic ovary syndrome (PCOS). Proceedings of the Society for Neuroscience 46th Annual Meeting. 60.19/KK14. SfN. Retrieved from https://www.sfn.org/
Conference Contribution - Published proceedings: Abstract
Moore, A. M., Prescott, M., Marshall, C. J., Yip, S. H., & Campbell, R. E. (2015). Enhancement of a robust arcuate GABAergic input to gonadotropin-releasing hormone neurons in a model of polycystic ovarian syndrome. PNAS, 112(2), 596-601. doi: 10.1073/pnas.1415038112
Journal - Research Article
Yip, S. H., Boehm, U., Herbison, A. E., & Campbell, R. E. (2015). Conditional viral tract tracing delineates the projections of the distinct kisspeptin neuron populations to gonadotropin-releasing hormone (GnRH) neurons in the mouse. Endocrinology, 156(7), 2582-2594. doi: 10.1210/en.2015-1131
Journal - Research Article
Seymour, A. J., Piet, R., Campbell, R. E., & Brown, C. H. (2015). Emergence of a kisspeptin projection from the periventricular nucleus to the perinuclear zone of the supraoptic nucleus during pregnancy. Proceedings of the 11th World Congress on Neurohypophysial Hormones (WCNH). (pp. 31). Retrieved from http://wcnh.otago.ac.nz/index.html
Conference Contribution - Published proceedings: Abstract
Seymour, A., Piet, R., Campbell, R. E., & Brown, C. H. (2015). Kisspeptin does not affect excitatory postsynaptic currents in supraoptic nucleus neurons from virgin or pregnant rats. Proceedings of the Society for Neuroscience 45th Annual Meeting. 613.23/S18. SfN. Retrieved from https://www.sfn.org
Conference Contribution - Published proceedings: Abstract
Campbell, R. E., & Herbison, A. E. (2014). Gonadal steroid neuromodulation of developing and mature hypothalamic neuronal networks. Current Opinion in Neurobiology, 29, 96-102. doi: 10.1016/j.conb.2014.06.003
Journal - Research Article
Shin, J., Prescott, M., Mair, J., & Campbell, R. E. (2014). Roles for primary cilia in gonadotropin-releasing hormone neurons in the mouse. Journal of Neuroendocrinology, 26(1), 18-25. doi: 10.1111/jne.12122
Journal - Research Article
Campbell, R. E., Prescott, M., Marshall, C., & Moore, A. (2014). Prenatal androgen exposure re-wires the gonadotropin-releasing hormone (GnRH) neuronal network. Proceedings of the Medical Sciences Congress (MedSci). (pp. 9). Retrieved from http://www.physoc.org.nz/meetings/archive/medsci-2014-abstracts
Conference Contribution - Published proceedings: Abstract
Marshall, C. J., Prescott, M., & Campbell, R. E. (2014). Pulsatile luteinizing hormone secretion is increased in a prenatal androgen (PNA) treated model of polycystic ovarian syndrome (PCOS). Proceedings of the Medical Sciences Congress (MedSci). (pp. 35). Retrieved from http://www.physoc.org.nz/meetings/archive/medsci-2014-abstracts
Conference Contribution - Published proceedings: Abstract
Marshall, C., Prescott, M., & Campbell, R. (2014). Measuring pulsatile luteinizing hormone secretion in a prenatal androgen treated model of polycystic ovarian syndrome. New Zealand Medical Journal, 127(1395). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Moore, A. M., Prescott, M., & Campbell, R. E. (2014). Defining the neuronal network mediating impaired progesterone negative feedback in a mouse model of polycystic ovarian syndrome. Proceedings of the Society for Neuroscience 44th Annual Meeting. SfN. Retrieved from http://www.sfn.org/annual-meeting/neuroscience-2014/abstracts
Conference Contribution - Published proceedings: Abstract
Moore, A. M., Prescott, M., & Campbell, R. E. (2014). Investigating changes in the gonadotropin-releasing hormone neuronal network in a model of polycystic ovarian syndrome. Proceedings of the Medical Sciences Congress (MedSci). (pp. 23). Retrieved from http://www.physoc.org.nz/meetings/archive/medsci-2014-abstracts
Conference Contribution - Published proceedings: Abstract
Moore, A. M., Prescott, M., & Campbell, R. E. (2013). Estradiol negative and positive feedback in a prenatal androgen-induced mouse model of polycystic ovarian syndrome. Endocrinology, 154(2), 796-806. doi: 10.1210/en.2012-1954
Journal - Research Article
Norberg, R., Campbell, R., & Suter, K. J. (2013). Ion channels and information processing in GnRH neuron dendrites. Channels, 7(3), 135-145. doi: 10.4161/chan.24228
Journal - Research Article
Clarke, I. J., Campbell, R., Smith, J. T., Prevot, V., & Wray, S. (2012). Neuroendocrine control of reproduction. In G. Fink, D. W. Pfaff & J. Levine (Eds.), Handbook of Neuroendocrinology. (pp. 197-235). Elsevier. doi: 10.1016/b978-0-12-375097-6.10009-5
Chapter in Book - Research
Campbell, R. E., Ducret, E., Porteous, R., Liu, X., Herde, M. K., Wellerhaus, K., … Herbison, A. E. (2011). Gap junctions between neuronal inputs but not gonadotropin-releasing hormone neurons control estrous cycles in the mouse. Endocrinology, 152(6), 2290-2301. doi: 10.1210/en.2010-1311
Journal - Research Article
Chan, H., Prescott, M., Ong, Z. Y., Herde, M. K., Herbison, A. E., & Campbell, R. E. (2011). Dendritic spine plasticity in gonadatropin-releasing hormone (GnRH) neurons activated at the time of the preovulatory surge. Endocrinology, 152(12), 4906-4914. doi: 10.1210/en.2011-1522
Journal - Research Article
Herde, M. K., Geist, K., Campbell, R. E., & Herbison, A. E. (2011). Gonadotropin-releasing hormone neurons extend complex highly branched dendritic trees outside the blood-brain barrier. Endocrinology, 152(10), 3832-3841. doi: 10.1210/en.2011-1228
Journal - Research Article
Campbell, R. E., & Suter, K. J. (2010). Redefining the gonadotrophin-releasing hormone neurone dendrite. Journal of Neuroendocrinology, 22, 650-658. doi: 10.1111/j.1365-2826.2010.02032.x
Journal - Research Article
Lee, K., Porteous, R., Campbell, R. E., Lüscher, B., & Herbison, A. E. (2010). Knockdown of GABAA receptor signaling in GnRH neurons has minimal effects upon fertility. Endocrinology, 151(9), 4428-4436. doi: 10.1210/en.2010-0314
Journal - Research Article
Campbell, R. E., Gaidamaka, G., Han, S.-K., & Herbison, A. E. (2009). Dendro-dendritic bundling and shared synapses between gonadotropin-releasing hormone neurons. PNAS, 106(26), 10835-10840. doi: 10.1073/pnas.0903463106
Journal - Research Article
Roberts, C. B., Campbell, R. E., Herbison, A. E., & Suter, K. J. (2008). Dendritic action potential initiation in hypothalamic gonadotropin-releasing hormone neurons. Endocrinology, 149(7), 3355-3360.
Journal - Research Article
Campbell, R. E. (2007). Defining the gonadotrophin-releasing hormone neuronal network: Transgenic approaches to understanding neurocircuitry. Journal of Neuroendocrinology, 19(7), 561-573. doi: 10.1111/j.1365-2826.2007.01568.x
Journal - Research Article
Campbell, R. E., & Herbison, A. E. (2007). Definition of brainstem afferents to gonadotropin-releasing hormone neurons in the mouse using conditional viral tract tracing. Endocrinology, 148(12), 5884-5890.
Journal - Research Article
Cottrell, E. C., Campbell, R. E., Han, S.-K., & Herbison, A. E. (2006). Postnatal remodeling of dendritic structure and spine density in gonadotropin-releasing hormone neurons. Endocrinology, 147(8), 3652-3661.
Journal - Research Article
Wintermantel, T. M., Campbell, R. E., Porteous, R., Bock, D., Gröne, H.-J., Todman, M. G., … Herbison, A. E. (2006). Definition of estrogen receptor pathway critical for estrogen positive feedback to gonadotropin-releasing hormone neurons and fertility. Neuron, 52, 271-280.
Journal - Research Article
Campbell, R. E., Han, S.-K., & Herbison, A. E. (2005). Biocytin filling of adult gonadotropin-releasing hormone neurons in situ reveals extensive, spiny, dendritic processes. Endocrinology, 146(3), 1163-1169.
Journal - Research Article
Campbell, R. E., Grove, K. L., & Smith, S. (2003). Distribution of corticotropin releasing hormone receptor immunoreactivity in the rat hypothalamus: Coexpression in neuropeptide Y and dopamine neurons in the arcuate nucleus. Brain Research, 973, 223-232.
Journal - Research Article
Campbell, R. E., Grove, K. L., & Smith, S. (2003). Gonadotropin-releasing hormone neurons coexpress orexin 1 receptor immunoreactivity and receive direct contacts by orexin fibers. Endocrinology, 144(4), 1542-1548.
Journal - Research Article
Campbell, R. E., Smith, S., Allen, S. E., Grayson, B. E., ffrench-Mullen, J. M. H., & Grove, K. L. (2003). Orexin neurons express a functional pancreatic polypeptide Y4 receptor. Journal of Neuroscience, 23(4), 1487-1497.
Journal - Research Article
Campbell, R. E., ffrench-Mullen, J. M. H., Cowley, M. A., Smith, M. S., & Grove, K. L. (2001). Hypothalamic circuitry of neuropeptide Y regulation of neuroendocrine function and food intake via the Y5 receptor subtype. Neuroendocrinology, 73, 106-119.
Journal - Research Article
Grove, K. L., Campbell, R. E., French-Mullen, J. M. H., Cowley, M. A., & Smith, M. S. (2000). Neuropeptide Y Y5 receptor expression in the cortical/limbic system and brainstem of the rat: Expression on γ-Aminobutyric acid and corticotropin-releasing hormone neurons. Neuroscience, 100(4), 731-740.
Journal - Research Article
Lu, N. Z., Shales, T. A., Dziennis, S. E., Campbell, R. E., & Bethea, C. L. (1999). Ovarian steroid action on tryptophan hydroxylase protein and serotonin compared to localization of ovarian steroid receptors in midbrain of guinea pigs. Endocrine, 11(3), 257-267.
Journal - Research Article
Professor Rebecca Campbell
Maggie Evans, Research Fellow
Kelly Glendining, Research Fellow
Kay Potapov, Assistant Research Fellow
Mel Prescott, Assistant Research Fellow