Principal Investigator
Associate Professor Rosie Brown
Email rosemary.brown@otago.ac.nz
Tel +64 3 479 8207
Fax 64 3 479 7323
Department of Physiology website
Research interests
I am interested in how the changing hormones of pregnancy and lactation act on neural circuitry in the maternal brain to influence behaviour. In particular, I focus on maternal behaviour, a complex set of behaviours displayed by a mother that promote the survival and wellbeing of her offspring. Our work aims to understand how hormones normally act to direct a mother's behaviour and how these processes may become disrupted.
At the Centre for Neuroendocrinology, I use transgenic mouse models to address the impact of specific neuroendocrine disruptions on maternal behaviour using behavioural assays. We investigate hormonal actions on neural circuitry underlying parental behaviour using a range of molecular, immunohistochemical and imaging approaches.
I am also interested in how changes in the ability of hormones to access the brain in different physiological or pathological states might underlie changes in hormone function.
Clinical conditions
- Postpartum depression
- Postpartum anxiety
- Maternal obesity
Rosie Brown Laboratory staff and students
Isaiah Cheong, Assistant Research Fellow
Neuroendocrine regulation of maternal behaviour
Email isaiah.cheong@otago.ac.nz
Jenny Clarkson, Research Fellow
Neural circuits required for maternal adaptation to pregnancy
Email jenny.clarkson@otago.ac.nz
Noelle James, Postdoctoral Fellow
Email noelle.james@otago.ac.nz
Jamie McQuillan, Research Fellow
Email jamie.mcquillan@otago.ac.nz
Nikkita Murray, PhD student
Email murni023@student.otago.ac.nz
Emmet Power, Research Fellow
Email emmet.power@otago.ac.nz
Michael Perkinson, Postdoctoral Fellow
Email michael.perkinson@otago.ac.nz
Vivienne Saunders, PhD student
Email sauvi647@student.otago.ac.nz
Belle Hoke, Master student