2011
Vella-Brincat JW, Begg EJ, Jensen BP, Chin PK, Roberts RL, Fairhall M, Macleod SA, Reid K. (2011) The pharmacokinetics and pharmacogenetics of the antiemetic cyclizine in palliative care patients. J Pain Symptom Manage. 43:540-8
Begg EJ, Helsby NA, Jensen BP.(2012) Pharmacogenetics of drug-metabolizing enzymes: the prodrug hypothesis. Pharmacogenomics. 13:83-9
Jensen BP, Roberts RL, Vyas R, Bonke G, Jardine DL, Begg EJ. (2012) Influence of ABCB1 (P-glycoprotein) haplotypes on nortriptyline pharmacokinetics and nortriptyline-induced postural hypotension in healthy volunteers. Br J Clin Pharmacol. 73:619-28
Begg EJ, Chin PK. (2012) A unified pharmacokinetic approach to individualized drug dosing. Br J Clin Pharmacol. 73:335-9
Jensen BP, Chin PK, Begg EJ. (2011) Quantification of total and free concentrations of R- and S-warfarin in human plasma by ultrafiltration and LC-MS/MS. Anal Bioanal Chem. 401:2187-93
Fergusson, D.M., Boden, J. Miller, A.L., Kennedy, M.A.Horwood, L.J. (2011) MAOA, abuse exposure, and antisocial behaviour: Findings from a 30 year longitudinal study. Brit J Psychiatry 198, 457-63
Fergusson, D.M., Horwood, L.J., Miller, A.L., Kennedy, M.A. (2011) Life Stress, 5HTTLPR and Mental Disorder: Findings from a 30 year longitudinal Study. Brit J Psychiatr. 198: 129 - 135
Chin PK, Jensen BP, Larsen HS, Begg EJ.(2011) Adult age and ex vivo protein binding of lorazepam, oxazepam and temazepam in healthy subjects. Br J Clin Pharmacol.72:985-9.
Larsen HS, Chin PK, Begg EJ, Jensen BP.(2011) Quantification of total and unbound concentrations of lorazepam, oxazepam and temazepam in human plasma by ultrafiltration and LC-MS/MS. Bioanalysis. 3:843-52
Jensen BP, Vella-Brincat JW, Begg EJ. (2011) Quantification of cyclizine and norcyclizine in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS). J Chromatogr B Analyt Technol Biomed Life Sci. 879:605-9
Maggo, S., Kennedy, M.A., Clark, D.W.J. (2011) Clinical implications of pharmacogenetic variation on the effects of statins. Drug Safety 34, 1-19
2010
Weersma, R.K., J.B. Crusius, R.L. Roberts, B.P. Koeleman, R. Palomino-Morales, et al. (2010). Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations. Inflamm Bowel Dis.
Stamp, L.K., J.L. O'Donnell, P.T. Chapman, M. Zhang, J. James, et al. (2010). Methotrexate polyglutamate concentrations are not associated with disease control in rheumatoid arthritis patients receiving long-term methotrexate therapy. Arthritis Rheum. 62: 359-68.
Stamp, L.K., P.T. Chapman, J.L. O'Donnell, M. Zhang, J. James, et al. (2010). Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate. Pharmacogenet Genomics. 20: 367-76.
Simms, L.A., J.D. Doecke, R.L. Roberts, E.V. Fowler, Z.Z. Zhao, et al. (2010). KCNN4 Gene Variant Is Associated With Ileal Crohn's Disease in the Australian and New Zealand Population. Am J Gastroenterol. 105: 2209-17.
Roberts, R.L., M. Zhang, A.M. Marinaki and L.K. Stamp (2010). Does genetic variability in aldehyde oxidase and molybdenum cofactor sulfurase predict nonresponse to allopurinol? Aliment Pharmacol Ther. 32: 310-1.
Roberts, R.L., R.K. Topless, A.J. Phipps-Green, R.B. Gearry, M.L. Barclay, et al. (2010). Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease. Genes Immun. 11: 351-6.
Roberts, R.L., T.R. Merriman and J.D. Upton (2010). High frequency of MCM6 lactose intolerance genotype in Polynesian people. Aliment Pharmacol Ther. 32: 828-9; author reply 829-30.
McHugh, P.C., G.R. Rogers, D.M. Glubb, P.R. Joyce and M.A. Kennedy (2010). Proteomic analysis of rat hippocampus exposed to the antidepressant paroxetine. J Psychopharmacol. 24: 1243-51.
McHugh, P.C., P.R. Joyce, X. Deng and M.A. Kennedy (2010). A polymorphism of the GTP-cyclohydrolase I feedback regulator gene alters transcriptional activity and may affect response to SSRI antidepressants. Pharmacogenomics J.
Joyce, P.R., K.J. Light, S.L. Rowe, C.R. Cloninger and M.A. Kennedy (2010). Self-mutilation and suicide attempts: relationships to bipolar disorder, borderline personality disorder, temperament and character. Aust N Z J Psychiatry. 44: 250-7.
Hollis-Moffatt, J.E., R.B. Gearry, M.L. Barclay, T.R. Merriman and R.L. Roberts (2010). Consolidation of evidence for association of the KIAA1109-TENR-IL2-IL21 rs6822844 variant with Crohn's disease. Am J Gastroenterol. 105: 1204-5; author reply 1206-7.
Harley, J., R. Roberts, P. Joyce, R. Mulder, S. Luty, et al. (2010). Orosomucoid influences the response to antidepressants in major depressive disorder. J Psychopharmacol. 24: 531-5.
Haines, M.L., Y. Ajlouni, P.M. Irving, M.P. Sparrow, R. Rose, et al. (2010). Clinical usefulness of therapeutic drug monitoring of thiopurines in patients with inadequately controlled inflammatory bowel disease. Inflamm Bowel Dis.
Glubb, D.M., P.C. McHugh, X. Deng, P.R. Joyce and M.A. Kennedy (2010). Association of a functional polymorphism in the adrenomedullin gene (ADM) with response to paroxetine. Pharmacogenomics J. 10: 126-33.
Gibson, P.R. and R.B. Gearry (2010). Optimizing thiopurine therapy: more weight to the metabolite argument. J Gastroenterol Hepatol. 25: 1592-4.
Gearry, R.B., A.K. Richardson, C.M. Frampton, A.J. Dodgshun and M.L. Barclay (2010). Population-based cases control study of inflammatory bowel disease risk factors. J Gastroenterol Hepatol. 25: 325-33.
Gearry, R.B., A.S. Day, M.L. Barclay, R.W. Leong and M.P. Sparrow (2010). Azathioprine and allopurinol: A two-edged interaction. J Gastroenterol Hepatol. 25: 653-5.
Eglinton, T.W. and R.B. Gearry (2010). Clinical factors predicting disease course in Crohn's disease. Expert Rev Clin Immunol. 6: 41-5.
Bryant, D.L., C.J. Miles and R.B. Gearry (2010). Nodular regenerative hyperplasia of the liver secondary to azathioprine in a patient with inflammatory bowel disease. N Z Med J. 123: 74-6.
Bonke, G. and B.P. Jensen (2010). Fast and sensitive LCMS/MS assay for quantification of nortriptyline and its active metabolites E- and Z-10-hydroxynortriptyline in human plasma. Bioanalysis. 2: 1553-1560.
Bentley, R.W., J. Pearson, R.B. Gearry, M.L. Barclay, C. McKinney, et al. (2010). Association of higher DEFB4 genomic copy number with Crohn's disease. Am J Gastroenterol. 105: 354-9.
Bentley, R.W., I. Cleynen, R.B. Gearry, M.L. Barclay, P. Rutgeerts, et al. (2010). Evidence that glioma-associated oncogene homolog 1 is not a universal risk gene for inflammatory bowel disease in Caucasians. Genes Immun. 11: 509-14.
2009
Zhang, M., G.A. Moore, M.L. Barclay and E.J. Begg (2009). Determination of perhexiline and its metabolite hydroxyperhexiline in human plasma by liquid chromatography/tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 877: 3025-30.
Stamp, L.K., J.L. O'Donnell, P.T. Chapman, M. Zhang, C. Frampton, et al. (2009). Determinants of red blood cell methotrexate polyglutamate concentrations in rheumatoid arthritis patients receiving long-term methotrexate treatment. Arthritis Rheum. 60: 2248-56.
Stamp, L.K., J.L. O'Donnell, P.T. Chapman, M.L. Barclay, M.A. Kennedy, et al. (2009). Lack of association between HLA-G 14 bp insertion/deletion polymorphism and response to long-term therapy with methotrexate response in rheumatoid arthritis. Ann Rheum Dis. 68: 154-5.
Doudney, K., JA Harley, JF Pearson, A Miller, A Aitchison, MA Kennedy, RJ Porter, JL Elmslie and PR Joyce. (2009) Upstream genetic variant near INSIG2, influences response to carnitine supplementation in bipolar patients with valproate induced weight gain. Acta Neuropsychiatrica. 3, 133–140.
Sharp, C.F., S.J. Gardiner, B.P. Jensen, R.L. Roberts, R.W. Troughton, et al. (2009). CYP2D6 genotype and its relationship with metoprolol dose, concentrations and effect in patients with systolic heart failure. Pharmacogenomics J. 9: 175-84.
Petermann, I., C.M. Triggs, C. Huebner, D.Y. Han, R.B. Gearry, et al. (2009). Mushroom intolerance: a novel diet-gene interaction in Crohn's disease. Br J Nutr. 102: 506-8.
Petermann, I., C. Huebner, B.L. Browning, R.B. Gearry, M.L. Barclay, et al. (2009). Interactions among genes influencing bacterial recognition increase IBD risk in a population-based New Zealand cohort. Hum Immunol. 70: 440-6.
McHugh, P.C., P.R. Joyce and M.R. Kennedy (2009). Polymorphisms of sepiapterin reductase gene alter promoter activity and may influence risk of bipolar disorder. Pharmacogenet Genomics. 19: 330-7.
Joyce, P.R., P.C. McHugh, K.J. Light, S. Rowe, A.L. Miller, et al. (2009). Relationships between angry-impulsive personality traits and genetic polymorphisms of the dopamine transporter. Biol Psychiatry. 66: 717-21.
Glubb, D.M., P.R. Joyce and M.A. Kennedy (2009). Expression and association analyses of promoter variants of the neurogenic gene HES6, a candidate gene for mood disorder susceptibility and antidepressant response. Neurosci Lett. 460: 185-90.
