Emeritus Professor Warren Tate

2026

Journal - Research Article

Bowden, N., McLeod, K., Anns, F., Catchpool, L., Charlton, F., Taylor, B., … Vu, H., & Tate, W. (2026). Health, labour market, and social service outcomes for people with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome on a health or disability related benefit: An Aotearoa | New Zealand nationwide cross-sectional study using the integrated data infrastructure. BMC Public Health. Advance online publication. doi: 10.1186/s12889-026-27499-7

McLoughlin, J., Sayfullaeva, J., Kiliç, E., Carmody, C., Grochowska, N., Potapov, K., Potapov, D., Clarkson, A., Peppercorn, K., Tate, W., & Kwakowsky, A. (2026). Estren prevents beta-amyloid-induced basal forebrain cholinergic loss and long-term spatial memory deficits in aged female mice. Scientific Reports. Advance online publication. doi: 10.1038/s41598-026-49638-1

O'Connell, A., Calvo-Flores Guzmán, B., Zhai, Y., Keighron, C. N., Boix, J., Peppercorn, K., Tate, W. P., … Kwakowsky, A. (2026). The β-amyloid-induced increased tonic conductance, impaired long-term potentiation and cognitive deficits characteristic of Alzheimer's disease are reversed by an α5 inverse agonist of the GABA type A receptor. Neuropharmacology, 290, 110892. doi: 10.1016/j.neuropharm.2026.110892

2025

Edited Book - Research

Tate, W. P., & Peppercorn, K. (Eds.). (2025). Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Methods and protocols: Methods in molecular biology (Vol. 2920). New York, NY: Humana Press. doi: 10.1007/978-1-0716-4498-0

Chapter in Book - Research

Sweetman, E., & Tate, W. P. (2025). Using the ratio of phosphorylated to non-phosphorylated forms of stress kinase PKR as a potential diagnostic test for ME/CFS. In W. P. Tate & K. Peppercorn (Eds.), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Methods and protocols: Methods in molecular biology (Vol. 2920). (pp. 13-28). New York, NY: Humana Press. doi: 10.1007/978-1-0716-4498-0_2

Peppercorn, K., Edgar, C. D., Al Momani, S., Rodger, E. J., Tate, W. P., & Chatterjee, A. (2025). Application of DNA methylome analysis to patients with ME/CFS. In W. P. Tate & K. Peppercorn (Eds.), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Methods and protocols: Methods in molecular biology (Vol. 2920). (pp. 141-160). New York, NY: Humana Press. doi: 10.1007/978-1-0716-4498-0_9

Edgar, C. D., Blair, A., & Tate, W. P. (2025). Measurement of genetic variations in ME/CFS patients in the IDO2 gene encoding an enzyme metabolizing tryptophan. In W. P. Tate & K. Peppercorn (Eds.), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Methods and protocols: Methods in molecular biology (Vol. 2920). (pp. 247-256). New York, NY: Humana Press. doi: 10.1007/978-1-0716-4498-0_14

Journal - Research Article

Sharma, S., Hodges, L. D., Peppercorn, K., Davis, J., Edgar, C. D., Rodger, E. J., Chatterjee, A., & Tate, W. P. (2025). Precision medicine study of post-exertional malaise epigenetic changes in myalgic encephalomyelitis/chronic fatigue patients during exercise. International Journal of Molecular Sciences, 26, 8563. doi: 10.3390/ijms26178563

Peppercorn, K., Sharma, S., Edgar, C. D., Stockwell, P. A., Rodger, E. J., Chatterjee, A., & Tate, W. P. (2025). Comparing DNA methylation landscapes in peripheral blood from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID patients. International Journal of Molecular Sciences, 26, 6631. doi: 10.3390/ijms26146631

Allan, A. C., Scott, B., Tate, W., Jameson, P. E., Macrae, E., Conner, A. J., … Caradus, J. (2025). Human-mediated outdoor genome editing is not possible so therefore poses no risk to the environment. Ecotoxicology & Environmental Safety, 302, 118609. doi: 10.1016/j.ecoenv.2025.118609

Journal - Research Other

Tate, W., Peppercorn, K., Bowden, N., & Charlton, F. (2025). Managing chronic fatigue conditions with overlapping symptoms, and the health policies and social services supporting those affected. Medical Research Archives, 13(11). doi: 10.18103/mra.v13i11.7104

Conference Contribution - Published proceedings: Abstract

Sharma, S., Peppercorn, K., Rodger, E., Tate, W. P., & Chatterjee, A. (2025). Developing a blood-based epigenomic signature for ME/CFS and Long COVID using Peripheral Blood Mononuclear Cells (PBMCs). Proceedings of the Genetics Otago (GO) Annual Symposium. Retrieved from https://blogs.otago.ac.nz/go

Griffiths, B. W. C., Peppercorn, K., Rodger, E., Chatterjee, A., & Tate, W. P. (2025). A genetic characterisation of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome predisposition. Proceedings of the Genetics Otago (GO) Annual Symposium. Retrieved from https://blogs.otago.ac.nz/go

Tate, W. P., Peppercorn, K., Griffiths, B. W. C., Sharma, S., Rodger, E., & Chatterjee, A. (2025). Understanding the genetics and epigenetics of the post-viral fatigue syndromes, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, and Long COVID. Proceedings of the Genetics Otago (GO) Annual Symposium. Retrieved from https://blogs.otago.ac.nz/go

Conference Contribution - Poster Presentation (not in published proceedings)

Sharma, S., Peppercorn, K., Rodger, E., Tate, W., & Chatterjee, A. (2025, February). Developing a blood-based epigenomic signature for ME/CFS and Long COVID using Peripheral Blood Mononuclear Cells (PBMCs). Poster session presented at the Maurice Wilkins Centre (MWC) Research Symposium, Auckland, New Zealand.

2024

Journal - Research Other

Tate, W. P., Peppercorn, K., Griffiths, B. W. C., & Sharma, S. (2024). The impact of COVID-19 on the understanding, management and treatment of post-viral conditions. Medical Research Archives, 12(9). doi: 10.18103/mra.v12i9.5644

Conference Contribution - Verbal presentation and other Conference outputs

Tate, W. (2024, December). DNA methylome analysis for developing a diagnostic panel for the post-viral fatigue syndromes, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, and Long COVID. Verbal presentation at the 10th Australasian Epienetics Alliance (AEpiA) Conference, Dunedin, New Zealand.

2023

Journal - Research Article

Peppercorn, K., Edgar, C. D., Kleffmann, T., & Tate, W. P. (2023). A pilot study on the immune cell proteome of long COVID patients shows changes to physiological pathways similar to those in myalgic encephalomyelitis/chronic fatigue syndrome. Scientific Reports, 13(1), 22068. doi: 10.1038/s41598-023-49402-9

Walker, M. O. M., Peppercorn, K., Kleffmann, T., Edgar, C. D., & Tate, W. P. (2023). An understanding of the immune dysfunction in susceptible people who develop the post-viral fatigue syndromes Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID. Medical Research Archives, 11(7). doi: 10.18103/mra.v11i7.1.4083

Peppercorn, K., Kleffmann, T., Hughes, S. M., & Tate, W. P. (2023). Secreted amyloid precursor protein alpha (sAPPα) regulates the cellular proteome and secretome of mouse primary astrocytes. International Journal of Molecular Sciences, 24, 7165. doi: 10.3390/ijms24087165

Tate, W. P., Walker, M. O. M., Peppercorn, K., Blair, A. L. H., & Edgar, C. D. (2023). Towards a better understanding of the complexities of myalgic encephalomyelitis/chronic fatigue syndrome and long COVID [Review]. International Journal of Molecular Sciences, 24(6), 5124. doi: 10.3390/ijms24065124

Conference Contribution - Published proceedings: Abstract

Stokes, C., Basak, I., Tate, W., & Hughes, S. (2023). Identifying superheroes in neurodegenerative disease. Proceedings of the Genetics Otago (GO) Annual Symposium & Workshops. Retrieved from https://blogs.otago.ac.nz/go

Conference Contribution - Poster Presentation (not in published proceedings)

Stokes, C., Basak, I., Tate, W., & Hughes, S. (2023, August). Identifying superheroes in neurodegenerative disease. Poster session presented at the Brain Health Research Centre (BHRC) Annual Conference, Dunedin, New Zealand.

2022

Journal - Research Article

Peppercorn, K., Kleffmann, T., Jones, O., Hughes, S., & Tate, W. (2022). Secreted amyloid precursor protein alpha, a neuroprotective protein in the brain has widespread effects on the transcriptome and proteome of human inducible pluripotent stem cell-derived glutamatergic neurons related to memory mechanisms. Frontiers in Neuroscience, 16, 858524. doi: 10.3389/fnins.2022.858524

Helliwell, A. M., Stockwell, P. A., Edgar, C. D., Chatterjee, A., & Tate, W. P. (2022). Dynamic epigenetic changes during a relapse and recovery cycle in myalgic encephalomyelitis/chronic fatigue ayndrome. International Journal of Molecular Sciences, 23(19), 11852. doi: 10.3390/ijms231911852

Walker, M. O. M., Hall, K. H., Peppercorn, K., & Tate, W. P. (2022). The significance of oxidative stress in the pathophysiology of Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Medical Research Archives, 10(9), 3050. doi: 10.18103/mra.v10i9.3050

Tate, W., Walker, M., Sweetman, E., Helliwell, A., Peppercorn, K., Edgar, C., Blair, A., & Chatterjee, A. (2022). Molecular mechanisms of neuroinflammation in ME/CFS and long COVID to sustain disease and promote relapses. Frontiers in Neurology, 13, 877772. doi: 10.3389/fneur.2022.877772

Lam, P., Vinnakota, C., Calvo-Flores Guzmán, B., Newland, J., Peppercorn, K., Tate, W. P., … Kwakowsky, A. (2022). Beta-amyloid (Aβ_1-42) increases the expression of NKCC1 in the mouse hippocampus. Molecules, 27, 2440. doi: 10.3390/molecules27082440

Guévremont, D., Tsui, H., Knight, R. G., Fowler, C. J., Masters, C. L., Martins, R. N., Abraham, W. C., Tate, W. P., Cutfield, N. J., & Williams, J. M. (2022). Plasma microRNA vary in association with the progression of Alzheimer's disease. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 14, e12251. doi: 10.1002/dad2.12251

Ohline, S. M., Chan, C., Schoderboeck, L., Wicky, H. E., Tate, W. P., Hughes, S. M., & Abraham, W. C. (2022). Effect of soluble amyloid precursor protein-alpha on adult hippocampal neurogenesis in a mouse model of Alzheimer's disease. Molecular Brain, 15, 5. doi: 10.1186/s13041-021-00889-1

Conference Contribution - Published proceedings: Abstract

Peppercorn, K., Kleffmann, T., Jones, O., Hughes, S., & Tate, W. (2022). Secreted amyloid precursor protein alpha has widespread effects on the transcriptome and proteome of human neurons related to memory mechanisms. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 64). Retrieved from https://www.queenstownresearchweek.org

Lam, P., Vinnakota, C., Calvo-Flores Guzmán, B., Newland, J., Peppercorn, K., Tate, W. P., … Kwakowsky, A. (2022). Investigating the expression of NKCC1 and KCC2 in Alzheimmer's disease mouse models. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 48). Retrieved from https://www.queenstownresearchweek.org

2021

Journal - Research Article

Livingstone, R. W., Elder, M. K., Singh, A., Westlake, C. M., Tate, W. P., Abraham, W. C., & Williams, J. M. (2021). Secreted amyloid precursor protein-alpha enhances LTP through the synthesis and trafficking of Ca²⁺-permeable AMPA receptors. Frontiers in Molecular Neuroscience, 14, 660208. doi: 10.3389/fnmol.2021.660208

Ryan, M., Tan, V. T. Y., Thompson, N., Guévremont, D., Mockett, B. G., Tate, W. P., Abraham, W. C., Hughes, S. M., & Williams, J. (2021). Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha promotes long-term induction of neuroprotective genes and pathways in a mouse model of Alzheimer’s disease. Journal of Alzheimer's Disease, 79, 1075-1090. doi: 10.3233/JAD-200757

Journal - Research Other

Bernhardt, H. S., & Tate, W. P. (2021). A new perspective on the Maillard reaction and the origin of life. Journal of Molecular Evolution, 89, 594-597. doi: 10.1007/s00239-021-10030-4

Wood, E., Hall, K. H., & Tate, W. (2021). Role of mitochondria, oxidative stress and the response to antioxidants in myalgic encephalomyelitis/chronic fatigue syndrome: A possible approach to SARS-CoV-2 ‘long-haulers’? Chronic Diseases & Translational Medicine, 7, 14-26. doi: 10.1016/j.cdtm.2020.11.002

Conference Contribution - Published proceedings: Abstract

Tate, W. (2021). The three macromolecules in the Central Dogma brought alive by over 60 years of biochemical and molecular studies assisted by visualisation and 'omic' technologies. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 160). Retrieved from https://www.faobmb2021.org

Westlake, C. M., Livingstone, R. W., Peppercorn, K., Tate, W. P., & Williams, J. M. (2021). Secreted amyloid precursor protein alpha (sAPPα) regulates surface expression of GluA1-containing glutamate receptors in primary hippocampal neurons. New Zealand Medical Journal, 134(1535), (pp. 98). Retrieved from https://www.nzma.org.nz/journal

2020

Journal - Research Article

Calvo-Flores Guzmán, B., Chaffey, T. E., Palpagama, T. H., Waters, S., Boix, J., Tate, W. P., Peppercorn, K., … Kwakowsky, A. (2020). The interplay between beta-amyloid 1-42 (Aβ_1-42)-induced hippocampal inflammatory response, p-tau, vascular pathology, and their synergistic contributions to neuronal death and behavioral deficits. Frontiers in Molecular Neuroscience, 13, 522073. doi: 10.3389/fnmol.2020.552073

Helliwell, A. M., Sweetman, E. C., Stockwell, P. A., Edgar, C. D., Chatterjee, A., & Tate, W. P. (2020). Changes in DNA methylation profiles of myalgic encephalomyelitis/chronic fatigue syndrome patients reflect systemic dysfunctions. Clinical Epigenetics, 12(1), 167. doi: 10.1186/s13148-020-00960-z

Sweetman, E., Kleffmann, T., Edgar, C., de Lange, M., Vallings, R., & Tate, W. (2020). A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction. Journal of Translational Medicine, 18, 365. doi: 10.1186/s12967-020-02533-3

Yeung, J. H. Y., Calvo-Flores Guzmán, B., Palpagama, H. T., Ethiraj, J., Zhai, Y., Tate, W. P., Peppercorn, K., … Kwakowsky, A. (2020). Amyloid-beta_1-42 induced glutamatergic receptor and transporter expression changes in the mouse hippocampus. Journal of Neurochemistry, 155, 62-80. doi: 10.1111/jnc.15099

Vinnakota, C., Govindpani, K., Tate, W. P., Peppercorn, K., Anekal, P. V., Waldvogel, H. J., … Kwakowsky, A. (2020). An α5 GABAA receptor inverse agonist, α5IA, attenuates amyloid beta-induced neuronal death in mouse hippocampal cultures. International Journal of Molecular Sciences, 21(9), 3284. doi: 10.3390/ijms21093284

Yeung, J. H. Y., Palpagama, T. H., Tate, W. P., Peppercorn, K., Waldvogel, H. J., Faull, R. L. M., & Kwakowsky, A. (2020). The acute effects of amyloid-Beta_1–42 on glutamatergic receptor and transporter expression in the mouse hippocampus. Frontiers in Neuroscience, 13, 1427. doi: 10.3389/fnins.2019.01427

Journal - Research Other

Calvo-Flores Guzmán, B., Kim, S., Chawdhary, B., Peppercorn, K., Tate, W. P., Waldvogel, H. J., … Kwakowsky, A. (2020). Amyloid-beta_1-42 -induced increase in GABAergic tonic conductance in mouse hippocampal CA1 pyramidal cells [Communication]. Molecules, 25(3), 693. doi: 10.3390/molecules25030693

Conference Contribution - Published proceedings: Abstract

Guévremont, D., Tsui, H., Knight, R., Fowler, C. J., Masters, C. L., Martins, R. N., Abraham, W. C., Tate, W. P., Cutfield, N., & Williams, J. M. (2020). Plasma microRNA vary in association with the progression in Alzheimer's disease. Proceedings of the Alzheimer's Association International Conference (AAIC). ODO2-09-06. Retrieved from https://alz.confex.com/alz/20amsterdam/meetingapp.cgi/Home/0

Conference Contribution - Verbal presentation and other Conference outputs

Tate, W. (2020, November). Understanding the biological basis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and its sudden increase in public profile with COVID-19. Verbal presentation at the Brain Health Research Centre Lecture and Poster Session, Dunedin, New Zealand.

2019

Journal - Research Article

Morrissey, J. A., Bigus, E., Necarsulmer, J. C., Srinivasan, V., Peppercorn, K., O'Leary, D. J., Mockett, B. G., Tate, W. P., Hughes, S. M., … Abraham, W. C. (2019). The tripeptide RER mimics secreted amyloid precursor protein-alpha in upregulating LTP. Frontiers in Cellular Neuroscience, 13, 459. doi: 10.3389/fncel.2019.00459

Livingstone, R. W., Elder, M. K., Barrett, M. C., Westlake, C. M., Peppercorn, K., Tate, W. P., Abraham, W. C., & Williams, J. M. (2019). Secreted amyloid precursor protein-alpha promotes arc protein synthesis in hippocampal neurons. Frontiers in Molecular Neuroscience, 12, 198. doi: 10.3389/fnmol.2019.00198

Morrissey, J. A., Mockett, B. G., Singh, A., Kweon, D., Ohline, S. M., Tate, W. P., Hughes, S. M., & Abraham, W. C. (2019). A C-terminal peptide from secreted amyloid precursor protein-α enhances long-term potentiation in rats and a transgenic mouse model of Alzheimer's disease. Neuropharmacology, 157, 107670. doi: 10.1016/j.neuropharm.2019.107670

Mockett, B. G., Guévremont, D., Elder, M. K., Parfitt, K. D., Peppercorn, K., Morrissey, J., Singh, A., Hintz, T. J., … Tate, W. P., Williams, J. M., & Abraham, W. C. (2019). Glutamate receptor trafficking and protein synthesis mediate the facilitation of LTP by secreted amyloid precursor protein-alpha. Journal of Neuroscience, 39(17), 3188-3203. doi: 10.1523/jneurosci.1826-18.2019

Sweetman, E., Ryan, M., Edgar, C., MacKay, A., Vallings, R., & Tate, W. (2019). Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome. International Journal of Immunopathology & Pharmacology, 33, 1-8. doi: 10.1177/2058738418820402

Journal - Research Other

Sweetman, E., Noble, A., Edgar, C., Mackay, A., Helliwell, A., Vallings, R., Ryan, M., & Tate, W. (2019). Current research provides insight into the biological basis and diagnostic potential for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Diagnostics, 9(3), 73. doi: 10.3390/diagnostics9030073

Conference Contribution - Published proceedings: Abstract

Kleffmann, T., Tate, W., & Hughes, S. (2019). Does secreted amyloid precursor protein alpha affect the global proteome of astrocytes? Proceedings of the 39th Australasian Neuroscience Society (ANS) Annual Scientific Meeting. 13247. Retrieved from https://www.ans.org.au

Chu, A. J., Peppercorn, K., Tate, W. P., Erlandsson, A., & Williams, J. M. (2019). Secreted amyloid precursor protein-alpha enhances amyloid-beta protofibril degradation in primary murine astrocytes. Proceedings of the 39th Australasian Neuroscience Society (ANS) Annual Scientific Meeting. 12828. Retrieved from https://www.ans.org.au

Ohline, S. M., Chan, C. H., Whelan, J., Smith, H., Logan, B. J., Morrissey, J. A., Schoderboeck, L., Peppercorn, K., Tate, W. P., Hughes, S. M., & Abraham, W. C. (2019). Stimulation of neurogenesis by a potential therapeutic protein. In K. Hillman (Ed.), Proceedings of the 37th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 57). Retrieved from http://www.otago.ac.nz/awcbr

Livingstone, R., Elder, M. K., Barrett, M., Westlate, C., Peppercorn, K., Tate, W., Abraham, W. C., & Williams, J. M. (2019). Arc protein synthesis is promoted by secreted amyloid precursor protein-alpha in primary hippocampal neurons. Proceedings of the Society for Neuroscience Annual Meeting. 286.17/C27. SfN. Retrieved from https://www.sfn.org

Conference Contribution - Verbal presentation and other Conference outputs

Helliwell, A. M., Chatterjee, A., Stockwell, P. A., & Tate, W. P. (2019, August-September). DNA methylation changes in myalgic encephalomyelitis/chronic fatigue syndrome. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2018

Chapter in Book - Other

Tate, W. P., & Marshall, C. J. (2018). Post-dormancy transcription and translation in the brine shrimp. In R. A. Browne, P. Sorgeloos & C. N. A. Trotman (Eds.), Artemia biology. (pp. 21-36). Boca Raton, FL: Taylor & Francis. doi: 10.1201/9781351069892

Journal - Research Article

Mackay, A., & Tate, W. P. (2018). A compromised paraventricular nucleus within a dysfunctional hypothalamus: A novel neuroinflammatory paradigm for ME/CFS. International Journal of Immunopathology & Pharmacology, 32, 1-8. doi: 10.1177/2058738418812342

Tan, V. T. Y., Mockett, B. G., Ohline, S. M., Parfitt, K. D., Wicky, H. E., Peppercorn, K., Schoderboeck, L., Yahaya, M. F. b., Tate, W. P., Hughes, S. M., & Abraham, W. C. (2018). Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease. Molecular Brain, 11, 7. doi: 10.1186/s13041-018-0348-9

Cridge, A. G., Crowe-McAuliffe, C., Mathew, S. F., & Tate, W. P. (2018). Eukaryotic translational termination efficiency is influenced by the 3' nucleotides within the ribosomal mRNA channel. Nucleic Acids Research, gkx1315. doi: 10.1093/nar/gkx1315

Journal - Research Other

Tate, W. P., Cridge, A. G., & Brown, C. M. (2018). 'Stop' in protein synthesis is modulated with exquisite subtlety by an extended RNA translation signal. Biochemical Society Transactions, 46(6), 1615-1625. doi: 10.1042/bst20180190

Conference Contribution - Published proceedings: Abstract

Elder, M. K., Tate, W. P., Abraham, W. C., Schman, E., & Williams, J. (2018). Secreted amyloid precursor protein alpha regulates AMPA receptor synthesis and trafficking. Proceedings of the 38th Australasian Neuroscience Society (ANS) Annual Scientific Meeting. 9274. Retrieved from https://www.ans.org.au

Yeung, J. H. Y., Calvo-Flores Guzman, B., Tate, W. P., Waldvogel, H. J., Faull, R. L. M., & Kwakowsky, A. (2018). Alterations in glutamate receptor and transporter expression in the hippocampus of an in vivo alzheimers disease mouse model. Proceedings of the 38th Australasian Neuroscience Society (ANS) Annual Scientific Meeting. 9266. Retrieved from https://www.ans.org.au

Williams, J. M., Elder, M. K., & Tate, W. P. (2018). Cell surface expression of GluA1-containing AMPA receptors is enhanced by secreted amyloid precursor protein-alpha; visualized by BioPLAy. Proceedings of the Society for Neuroscience 48th Annual Meeting. 285.15/E44. SfN. Retrieved from https://www.sfn.org

Livingstone, R. W., Elder, M. K., Barrett, M., Westlake, C., Tate, W., Abraham, W., & Williams, J. M. (2018). Arc protein expression in response to secreted amyloid precursor protein-α in primary hippocampal cultures. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 60). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr

Potemkin, N., Tate, W. P., & Williams, J. M. (2018). Amyloid-β increases SH-SY5y neuroblastoma cell viability. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 57). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr

Vinnakota, C., Govindpani, K., Calvo-Flores Guzman, B., Tate, W. P., Waldvogel, H. J., Faull, R. L. M., & Kwakowsky, A. (2018). Extrasynaptic α5 type GABA_A receptors as therapeutic targets for Alzheimer's disease. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 47). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr

Conference Contribution - Poster Presentation (not in published proceedings)

Helliwell, A. M., & Tate, W. P. (2018, November). Insights from DNA methylation analysis into the aetiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, a disease predominantly affecting women. Poster session presented at the Women’s Wellbeing Symposium, Dunedin, New Zealand.

2017

Journal - Research Article

Xiong, M., Jones, O. D., Peppercorn, K., Ohline, S. M., Tate, W. P., & Abraham, W. C. (2017). Secreted amyloid precursor protein-alpha can restore novel object location memory and hippocampal LTP in aged rats. Neurobiology of Learning & Memory, 138, 291-299. doi: 10.1016/j.nlm.2016.08.002

Conference Contribution - Published proceedings: Abstract

Vinnakota, C., Govindpani, K., Calvo-Flores, G. B., Tate, W. P., Waldvogel, H. J., Faull, R. L. M., & Kwakowsky, A. (2017). Extrasynaptic alpha 5 type GABAA receptors as therapeutic targets for Alzheimer's disease. Proceedings of the Australasian Neuroscience Society 37th Annual Scientific Meeting. Retrieved from http://ans2017.aomevents.com.au

Calvo-Flores, G. B., Waters, S., Fuhrer, T., Palpagama, T., Tate, W. P., Dragunow, M., … Kwakowsky, A. (2017). Beta-amyloid (AB 1-42) -induced molecular and cellular changes in the hippocampus in an in vivo mouse model of Alzheimer's disease. Proceedings of the Australasian Neuroscience Society 37th Annual Scientific Meeting. Retrieved from http://ans2017.aomevents.com.au

Mockett, B. G., Guévremont, D., Parfitt, K., Elder, M., Peppercorn, K., Kochen, L., … Tate, W. P., Williams, J. M., & Abraham, W. C. (2017). Glutamate receptor trafficking and protein synthesis mediate the facilitation of LTP by secreted amyloid precursor protein-alpha. Proceedings of the Australasian Neuroscience Society 37th Annual Scientific Meeting. Retrieved from http://ans2017.aomevents.com.au

Sweetman, E. C., Tate, W. P., & Ryan, M. (2017). Investigating molecular diagnostic biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome. New Zealand Medical Journal, 130(1467), (pp. 106). Retrieved from http://www.nzma.org.nz/journal

Elder, M., Peppercorn, K., Schuman, E. M., Tate, W. P., Abraham, W. C., & Williams, J. M. (2017). Secreted amyloid precursor protein alpha regulated AMPA receptor synthesis and trafficking. In B. Leitch (Ed.), Proceedings of the 35th International Australasian Winter Conference on Brain Research. (pp. 58). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr/index.html

2016

Journal - Research Article

Kwakowsky, A., Potapov, K., Kim, S., Peppercorn, K., Tate, W. P., & Ábrahám, I. M. (2016). Treatment of beta amyloid 1-42 (Αβ_1-42)-induced basal forebrain cholinergic damage by a non-classical estrogen signaling activator in vivo. Scientific Reports, 6, 21101. doi: 10.1038/srep21101

Conference Contribution - Published proceedings: Full paper

Tate, W. P., Sweetman, E. C., Noble, A. J. K., Edgar, C. D., Bateman, G., MacKay, A., Ryan, M. M., … Vallings, R. (2016). Tackling ME/CFS in New Zealand by the principles of precision medicine. Journal of Iimer, 10(1), (pp. 46-55). Retrieved from http://publizr.com/investinmeresearch/journal-of-iime-vol-10-issue-1#/0

Conference Contribution - Published proceedings: Abstract

Parfitt, K. D., Mockett, B., Hintz, T. J., Bourne, K., Williams, J. M., Tate, W. P., & Abraham, W. C. (2016). Secreted amyloid precursor protein-alpha enhances long-term potentiation via protein synthesis- and protein trafficking-dependent mechanisms. Alzheimer's & Dementia, 12(7, Suppl.), (pp. P1040). doi: 10.1016/j.jalz.2016.06.2159

Williams, J. M., Guevremont, D., Mockett, B., Peppercorn, K., Tate, W. P., & Abraham, W. C. (2016). Secreted amyloid precursor protein-alpha regulates glutamate receptor trafficking in the hippocampus. Alzheimer's & Dementia, 12(7, Suppl.), (pp. P1040-P1041). doi: 10.1016/j.jalz.2016.06.2160

Morrissey, J., Mockett, B. G., Peppercorn, K., Tate, W. P., Hughes, S. M., & Abraham, W. C. (2016). Peptides of amyloid precursor protein alpha mimic the parent molecule's enhancement of hippocampal LTP. Proceedings of the Society for Neuroscience 46th Annual Meeting. 131.19/K17. SfN. Retrieved from https://www.sfn.org/

Elder, M. K., Peppercorn, K., tom Dieck, S., Kochen, L., Schuman, E., Tate, W., Abraham, C., & Williams, J. (2016). Secreted amyloid precursor protein-alpha regulates synthesis of the AMPA receptor subunit GluA1. Proceedings of the Society for Neuroscience 46th Annual Meeting. 397.08/E29. SfN. Retrieved from https://www.sfn.org/

Palpagama, T. H., Tate, W. P., Waldvogel, H. J., Faull, R. L., & Kwakowsky, A. (2016). Investigation of GABA signalling in an in-vivo Alzheimer’s disease mouse model. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 41). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr

2015

Journal - Research Article

Cardno, T. S., Shimaki, Y., Sleebs, B. E., Lackovic, K., Parisot, J. P., Moss, R. M., Crowe-McAuliffe, C., Mathew, S. F., Edgar, C. D., Kleffmann, T., & Tate, W. P. (2015). HIV-1 and human PEG10 frameshift elements are functionally distinct and distinguished by novel small molecule modulators. PLoS ONE, 10(10), e0139036. doi: 10.1371/journal.pone.0139036

Ramsay, J. P., Tester, L. G. L., Major, A. S., Sullivan, J. T., Edgar, C. D., Kleffmann, T., … Tate, W. P., … Ronson, C. W. (2015). Ribosomal frameshifting and dual-target antiactivation restrict quorum-sensing–activated transfer of a mobile genetic element. PNAS, 112(3), 4104-4109. doi: 10.1073/pnas.1501574112

Mathew, S. F., Crowe-McAuliffe, C., Graves, R., Cardno, T. S., McKinney, C., Poole, E. S., & Tate, W. P. (2015). The highly conserved codon following the Slippery Sequence Supports -1 frameshift efficiency at the HIV-1 frameshift site. PLoS ONE, 10(3), e0122176. doi: 10.1371/journal.pone.0122176

Conference Contribution - Published proceedings: Abstract

Kwakowsky, A., Waldvogel, H. J., Faull, R. L. M., Arasaratnam, C., Tate, W. P., & Peppercorn, K. (2015). Impaired GABA_A receptor function in Alzheimer's disease. In B. Leitch (Ed.), Proceedings of the 33rd International Australasian Winter Conference on Brain Research. (pp. 70). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr

Morrissey, J., Mockett, B. G., Peppercorn, K., Tate, W. P., Hughes, S. M., & Abraham, W. C. (2015). Fragments of amyloid precursor protein enhance rat hippocampal LTP. In B. Leitch (Ed.), Proceedings of the 33rd International Australasian Winter Conference on Brain Research. (pp. 65). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr

Elder, M., Peppercorn, K., Schuman, E., Tate, W. P., Abraham, W. C., & Williams, J. M. (2015). Secreted amyloid precursor protein alpha regulates protein synthesis in primary hippocampal neuronal cultures. In B. Leitch (Ed.), Proceedings of the 33rd International Australasian Winter Conference on Brain Research. (pp. 28). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr

Elder, M., Peppercorn, K., Schuman, E., Tate, W., Abraham, C., & Williams, J. (2015). Secreted amyloid precursor protein alpha regulates protein synthesis in primary hippocampal neuronal cultures. Journal of Neurochemistry, 134(Suppl. 1), (pp. 302). doi: 10.1111/jnc.13189

Conference Contribution - Poster Presentation (not in published proceedings)

Sweetman, E. C., & Tate, W. P. (2015, August-September). Developing a diagnostic test for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome based on the anti-viral immune protein Protein Kinase R. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2014

Conference Contribution - Published proceedings: Abstract

Kwakowsky, A., Potapov, K., Kim, S., Peppercorn, K., Tate, W. P., & Abraham, I. M. (2014). Effects and mechanism of action of estren on beta amyloid-induced cholinergic and behavioural deficits. Proceedings of the Society for Neuroscience 44th Annual Meeting. SfN. Retrieved from http://www.sfn.org/annual-meeting/neuroscience-2014/abstracts

Yahaya, M. F., Parfitt, K. D., Mockett, B. G., Schoderböck, L., Peacock, H. E., Bourne, K., Tate, W. P., Hughes, S. M., & Abraham, W. C. (2014). Secreted amyloid precursor protein-α overexpression in vivo rescues the long-term potentiation deficit in a mouse model of Alzheimer’s disease. Proceedings of the Society for Neuroscience 44th Annual Meeting. SfN. Retrieved from http://www.sfn.org/annual-meeting/neuroscience-2014/abstracts

Parfitt, K. D., Mockett, B. G., Guevremont, D., Bourne, K., Tate, W. P., Williams, J. M., & Abraham, W. C. (2014). Secreted amyloid precursor protein-alpha (sAPPα) modulates long-term potentiation, induces metaplasticity and regulates glutamate receptor localization in rat hippocampus. Proceedings of the Society for Neuroscience 44th Annual Meeting. SfN. Retrieved from http://www.sfn.org/annual-meeting/neuroscience-2014/abstracts

Xiong, M., Jones, O., Peppercorn, K., Tate, W., & Abraham, W. (2014). Administration of secreted amyloid precursor protein-α rescues spatial memory and long-term potentiation deficits in aged rats. New Zealand Medical Journal, 127(1406). Retrieved from http://www.nzma.org.nz/journal

Elder, M., Mockett, B. G., Blok, J., Peppercorn, K., Tate, W. P., Abraham, W. C., & Williams, J. M. (2014). Secreted amyloid precursor protein-α attenuates apoptosis following amyloid-β insult and ischemic injury. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 32nd International Australasian Winter Conference on Brain Research. 32, (pp. 62). AWCBR. Retrieved from https://web.psy.otago.ac.nz/awcbr/proceedings.html

Xiong, M., Jones, O. D., Bourne, K., Tate, W. P., & Abraham, W. C. (2014). The effects of exogenous sAPPα on spatial memory and LTP in aging. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 32nd International Australasian Winter Conference on Brain Research. 32, (pp. 48). AWCBR. Retrieved from https://web.psy.otago.ac.nz/awcbr/proceedings.html

Kwakowsky, A., Potapov, K., Peppercorn, K., Kim, S., Tate, W. P., & Ábrahám, I. M. (2014). Effects and mechanism of action of estren on beta amyloid-induced cholinergic and behavioural deficits. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 32nd International Australasian Winter Conference on Brain Research. 32, (pp. 35). AWCBR. Retrieved from https://web.psy.otago.ac.nz/awcbr/proceedings.html

2013

Journal - Research Article

Ryan, M. M., Morris, G. P., Mockett, B. G., Bourne, K., Abraham, W. C., Tate, W. P., & Williams, J. M. (2013). Time-dependent changes in gene expression induced by secreted amyloid precursor protein-alpha in the rat hippocampus. BMC Genomics, 14, 376. doi: 10.1186/1471-2164-14-376

Imhoff, F. M., Yang, D., Mathew, S. F., Clarkson, A. N., Kawagishi, Y., Tate, W. P., Koishi, K., & McLennan, I. S. (2013). The type 2 anti-Müllerian hormone receptor has splice variants that are dominant-negative inhibitors. FEBS Letters, 587(12), 1749-1753. doi: 10.1016/j.febslet.2013.04.014

Conference Contribution - Published proceedings: Abstract

Parfitt, K. D., Bourne, K., Hintz, T. J., Tate, W. P., & Abraham, W. C. (2013). Secreted APPα rescues LTP deficits in APPswe/PS1ΔE9 transgenic mice. Proceedings of the Society for Neuroscience 43rd Annual Meeting. SfN. Retrieved from http://www.sfn.org/annual-meeting/neuroscience-2013/abstracts-and-sessions

Kwakowsky, A., Kim, S., Tate, W. P., & Abraham, I. M. (2013). Estren treatment attenuates beta amyloid-induced cholinergic and behavioural deficits. Proceedings of the Society for Neuroscience 43rd Annual Meeting. SfN. Retrieved from http://www.sfn.org/annual-meeting/neuroscience-2013/abstracts-and-sessions

Williams, J. M., Guévremont, D., Tsui, H., Logan, B., Knight, R., Abraham, W. C., Tate, W. P., & Cutfield, N. (2013). Altered expression of plasma microRNA in sporadic Alzheimer's disease. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 31st International Australasian Winter Conference on Brain Research. 31, (pp. 70). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2013copy.html

Conference Contribution - Verbal presentation and other Conference outputs

Kwakowsky, A., Kim, S. H., Tate, W. P., & Ábrahám, I. M. (2013, August). Estren treatment attenuates beta amyloid-induced cholinergic and behavioural deficits. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2012

Journal - Research Article

Bernhardt, H. S., & Tate, W. P. (2012). Primordial soup or vinaigrette: Did the RNA world evolve at acidic pH? Biology Direct, 7(4). doi: 10.1186/1745-6150-7-4

Ryan, M. M., Ryan, B., Kyrke-Smith, M., Logan, B., Tate, W. P., Abraham, W. C., & Williams, J. M. (2012). Temporal profiling of gene networks associated with the late phase of long-term potentiation in vivo. PLoS ONE, 7(7), e40538. doi: 10.1371/journal.pone.0040538

Baratchi, S., Evans, J., Tate, W. P., Abraham, W. C., & Connor, B. (2012). Secreted amyloid precursor proteins promote proliferation and glial differentiation of adult hippocampal neural progenitor cells. Hippocampus, 22(7), 1517-1527. doi: 10.1002/hipo.20988

Conference Contribution - Published proceedings: Abstract

Overeem, K. A., Guévremont, D., Bilkey, D. K., Tate, W. P., Abraham, W. C., & Williams, J. M. (2012). Comparison of methods for the isolation of microRNA from rat and human plasma: Beginning the search for biomarkers of neurological disorders. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 124). Retrieved from http://www.ans.org.au/ans-annual-conference/

Conference Contribution - Poster Presentation (not in published proceedings)

MacKay, A., Tate, W., & Poole, E. (2012, August). Developing a blood test for myalgic encephalomyelitis (ME): miRNA as putative biomarkers. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Bernhardt, H. S., & Tate, W. P. (2012, August). Primordial soup or vinaigrette: Did the RNA world evolve at acidic pH? Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Tate, W. P. (2012, August). Old actors in a contemporary drama: Ancestral signatures of the RNA precursors to the modern ribosome. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2011

Journal - Research Article

Morgan, N. V., Goddard, S., Cardno, T. S., McDonald, D., Rahman, F., Barge, D., Ciupek, A., … Tate, W. P., … Maher, E. R. (2011). Mutation in the TCRα subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRαβ⁺ T cells. Journal of Clinical Investigation, 121(2), 695-702. doi: 10.1172/JCI41931

Ryan, M. M., Mason-Parker, S. E., Tate, W. P., Abraham, W. C., & Williams, J. M. (2011). Rapidly induced gene networks following induction of long-term potentiation at perforant path synapses in vivo. Hippocampus, 21(5), 541-553. doi: 10.1002/hipo.20770

Conference Contribution - Published proceedings: Full paper

Tate, W. P., & Poole, E. S. (2011). Establishing a research base and clinical sample bank in New Zealand with emphasis on developing diagnostic biomarkers: RNase L cleavage, and PKR-mediated shutdown of protein synthesis through phosphorylation mechanisms. Proceedings of the International Science Symposium on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). (pp. 28-32). North Sydney, Australia: Alison Hunter Memorial Foundation. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Ryan, M. M., Morris, G., Mockett, B. G., Bourne, K., Abraham, W. C., Tate, W. P., & Williams, J. M. (2011). Secreted amyloid precursor protein-alpha regulates hippocampal gene expression. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 163). Retrieved from http://www.ans.org.au/uploads/documents/2011%20Docs/conference%20abstracts/ANS%202011%20Poster%20Abstracts.pdf

Morris, G. P., Ryan, M. M., Bourne, K., & Tate, W. P. (2011). Understanding how secreted amyloid precursor protein-α (SAPPα) signals changes in gene expression in neurons. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 160). Retrieved from http://www.ans.org.au/uploads/documents/2011%20Docs/conference%20abstracts/ANS%202011%20Poster%20Abstracts.pdf

Claasen, A. M., Guévremont, D., Abraham, W. C., Tate, W. P., & Williams, J. M. (2011). Secreted amyloid precursor protein-alpha activates MAP kinase and CaM kinase signalling pathways at rat cortical synapses. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 91). Retrieved from http://www.ans.org.au/uploads/documents/2011%20Docs/conference%20abstracts/ANS%202011%20Poster%20Abstracts.pdf

Abraham, W. C., Baratchi, S., Evans, J., Tate, W. P., & Connor, B. (2011). Secreted amyloid precursor proteins promote proliferation and glial differentiation of adult hippocampal neural progenitor cells. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 8.5. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html

Morris, G., Ryan, M., Bourne, K., & Tate, W. (2011). Secreted amyloid precursor protein-α mediates gene expression. New Zealand Medical Journal, 124(1346). Retrieved from http://journal.nzma.org.nz/journal/124-1346/4980/content.pdf

Conference Contribution - Poster Presentation (not in published proceedings)

Crowe-McAuliffe, C. T., Clark, M. B., Tate, W. P., & Poole, E. S. (2011, September). Analysis of the human retroviral-like PEG10 protease domain. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Bernhardt, H. S., & Tate, W. P. (2011, July). Small RNAs illuminate the dawn of coded protein synthesis. Poster session presented at the International Society for the Study of the Origin of Life (ISSOL) and Bioastronomy Joint International Conference, Montpellier, France.

Bernhardt, H. S., & Tate, W. P. (2011, July). The ribonucleic acid world: Did it evolve at low pH? Poster session presented at the International Society for the Study of the Origin of Life (ISSOL) and Bioastronomy Joint International Conference, Montpellier, France.

Conference Contribution - Verbal presentation and other Conference outputs

Tate, W. (2011, July). A slippery slope in HIV translating to lead compounds for a new class of antiviral drugs. Verbal presentation at the Brain Health Research Centre Conference, Dunedin, New Zealand.

2010

Journal - Research Article

Young, D. J., Edgar, C. D., Poole, E. S., & Tate, W. P. (2010). The codon specificity of eubacterial release factors is determined by the sequence and size of the recognition loop. RNA, 16, 1623-1633. doi: 10.1261/rna.2117010

Young, D. J., Edgar, C. D., Murphy, J., Fredebohm, J., Poole, E. S., & Tate, W. P. (2010). Bioinformatic, structural, and functional analyses support release factor-like MTRF1 as a protein able to decode nonstandard stop codons beginning with adenine in vertebrate mitochondria. RNA, 16(6), 1146-1155. doi: 10.1261/rna.1970310

Bernhardt, H. S., & Tate, W. P. (2010). The transition from noncoded to coded protein synthesis: Did coding mRNAs arise from stability-enhancing binding partners to tRNA? Biology Direct, 5, 16. doi: 10.1186/1745-6150-5-16

Conference Contribution - Published proceedings: Abstract

Mukadam, A., Bourne, K., & Tate, W. (2010). The unique C-terminal region of secreted amyloid precursor protein alpha is crucial for neuroprotection. Proceedings of the 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society (ANS/AuPS). (pp. 181). Retrieved from http://www.sallyjayconferences.com.au/sydney2010/abstracts.html

Conference Contribution - Verbal presentation and other Conference outputs

Bernhardt, H., & Tate, W. P. (2010, January-February). The origin of genetic coding: Evolution of coded protein synthesis from a frozen accident, and serendipitous binding partners. Verbal presentation at the 23rd tRNA Workshop: From the origin of life to biomedicine, Aveiro, Portugal.

Intellectual Property

Cardno, T. S., & Tate, W. P. (2010). Dual-fluorescent reporter construct and assay for measuring translational recoding. (EP 1 929 015).

Other Research Output

Tate, W. (2010, July). Secreted amyloid precursor protein (sAPPalpha): Is this a lead compound to protect against Alzheimer's disease?. University of Otago Department of Pharmacology & Toxicology Seminar, Dunedin, New Zealand. [Department Seminar].

2009

Journal - Research Article

Cardno, T. S., Poole, E. S., Mathew, S. F., Graves, R., & Tate, W. P. (2009). A homogeneous cell-based bicistronic fluorescence assay for high-throughput identification of drugs that perturb viral gene recoding and read-through of nonsense stop codons. RNA, 15(8), 1614-1621. doi: 10.1261/rna.1586709

Claasen, A. M., Guévremont, D., Mason-Parker, S. E., Bourne, K., Tate, W. P., Abraham, W. C., & Williams, J. M. (2009). Secreted amyloid precursor protein-α upregulates synaptic protein synthesis by a protein kinase G-dependent mechanism. Neuroscience Letters, 460, 92-96. doi: 10.1016/j.neulet.2009.05.040

Jacobs, G. H., Chen, A., Stevens, S. G., Stockwell, P. A., Black, M. A., Tate, W. P., & Brown, C. M. (2009). Transterm: A database to aid the analysis of regulatory sequences in mRNAs. Nucleic Acids Research, 37(Database issue), D72-D76. doi: 10.1093/nar/gkn763

Conference Contribution - Published proceedings: Abstract

Morgan, N. V., Goddard, S., Cardno, T. S., Rahman, F., Ciupek, A., Straatman-Iwanowska, A., … Tate, W. P., & Maher, E. R. (2009). A novel human immunodeficiency disorder associated with a mutation in the T cell receptor α subunit constant gene (TRAC). Proceedings of the American Society of Human Genetics 59th Annual Meeting. (pp. 734). Retrieved from http://www.ashg.org/2009meeting/pdf/poster_4up.pdf

Poole, E. S., Saurat, N., Crowe-McAuliffe, C., Shimaki, Y., Clark, M., & Tate, W. P. (2009). RNA recoding and microRNAs regulate the expression of the human gene PEG10. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Bernhardt, H. S., & Tate, W. P. (2009). The RNA code: The origin of coded protein synthesis. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Tate, W. P., Young, D. J., Poole, E. S., & Edgar, C. D. (2009). Recognition of the RNA code of vertebrate mitochondria. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Morgan, N., Goddard, S., Cardno, T. S., Rahman, F., Ciupek, A., . . ., Tate, W. P., & et al (2009). A novel human immunodeficiency disorder associated with a mutation in the T cell receptor αsubunit constant gene (TRAC). Journal of Medical Genetics, 46(Suppl. 1), (pp. S15). [Abstract]

Ryan, M. M., Morris, G., Bourne, K., Mockett, B. G., Abraham, W. C., Tate, W. P., & Williams, J. M. (2009). Regulation of gene expression by sAPPα and RER derivative in differentiated neuroblastoma cells. Alzheimer's & Dementia, 5(4, Suppl. 1), (pp. P421). doi: 10.1016/j.jalz.2009.04.938

Cardno, T. S., Poole, E. S., Mathew, S. F., Graves, R., & Tate, W. P. (2009). A homogenous cell based bicistronic fluorescence assay for high-throughput sceening. Proceedings of the Webster Centre for Infectious Diseases Symposium. WCID. Retrieved from http://www.webstercentre.otago.ac.nz/WCIDSymposiumProgramme.pdf

Tate, W., Poole, E., Edgar, T., Cardno, T., Mathew, S., Shimaki, Y., James, S., Crowe-McAuliffe, C., Peat, J., & Saurat, N. (2009). The translational frameshift mechanism of HIV-1 as a drug target: Can damage to the same mechanism in human gene PEG10 be avoided? Proceedings of the Webster Centre for Infectious Diseases Symposium. WCID. Retrieved from http://www.webstercentre.otago.ac.nz/WCIDSymposiumProgramme.pdf

Conference Contribution - Poster Presentation (not in published proceedings)

Bernhardt, H. S., & Tate, W. P. (2009, May-June). The transition from noncoded to coded protein synthesis: Did mRNAs arise as binding partners to tRNAs? Poster session presented at the LXXIV Cold Spring Harbor Symposium on Quantitative Biology: Evolution: The Molecular Landscape, Cold Spring Harbor, USA.

2008

Journal - Research Article

Bernhardt, H. S., & Tate, W. P. (2008). Evidence from glycine transfer RNA of a frozen accident at the dawn of the genetic code. Biology Direct, 3, 53. doi: 10.1186/1745-6150-3-53

Bernhardt, H. S., & Tate, W. P. (2008). Self-assembling transfer RNA has potential for nanoparticle arrays. Current Applied Physics, 8(3-4), 380-382. doi: 10.1016/j.cap.2007.10.035

Taylor, C. J., Ireland, D. R., Ballagh, I., Bourne, K., Marechal, N. M., Turner, P. R., Bilkey, D. K., Tate, W. P., & Abraham, W. C. (2008). Endogenous secreted amyloid precursor protein-α regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory. Neurobiology of Disease, 31(2), 250-260. doi: 10.1016/j.nbd.2008.04.011

Conference Contribution - Published proceedings: Abstract

Renshaw, J. A., Ryan, M., Williams, J., & Tate, W. (2008). Recombinant sAPPα causes specific changes in gene expression in neuroblastoma cells and rat hippocampal cell slices. New Zealand Medical Journal, 121(1274). Retrieved from http://journal.nzma.org.nz/journal/121-1274/3078/content.pdf

Claasen, A. M., Guévremont, D., Mason-Parker, S. E., Bourne, K., Tate, W. P., Abraham, W. C., & Williams, J. M. (2008). Secreted amyloid precursor protein alpha-dependent upregulation of synaptic protein synthesis is dose and protein kinase G-dependent. In J. G. Anson (Ed.), Proceedings of the 26th International Australasian Winter Conference on Brain Research. 26, (pp. 46). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2008Abstracts.pdf

Abraham, W. C., Marechal, N. M., Logan, B. J., Bourne, K., & Tate, W. P. (2008). Regulation of spatial memory processing by endogenous secreted amyloid precursor protein-α. In J. G. Anson (Ed.), Proceedings of the 26th International Australasian Winter Conference on Brain Research. 26, (pp. 23). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2008Abstracts.pdf

Conference Contribution - Poster Presentation (not in published proceedings)

Mukadam, A., & Tate, W. (2008, November-December). Characterisation of the function of the C-terminal 16 amino acids of sAPPα. Poster session presented at the New Zealand Institute of Chemistry, New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Biologists Combined Conference, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Bernhardt, H. S., & Tate, W. P. (2008, November-December). Evidence from glycine transfer RNA of a 'frozen accident' at the dawn of the genetic code. Verbal presentation at the New Zealand Institute of Chemistry, New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Biologists Combined Conference, Dunedin, New Zealand.

Tate, W., Bourne, K., Turner, P. R., Claasen, A., Ryan, M., Taylor, C., Ireland, D., Ballagh, I., Marechal, N., Bilkey, D., Williams, J., & Abraham, W. (2008, November-December). Secreted amyloid precursor protein alpha: A mammalian memory molecule. Verbal presentation at the New Zealand Institute of Chemistry, New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Biologists Combined Conference, Dunedin, New Zealand.

2007

Journal - Research Article

Clark, M. B., Jänicke, M., Gottesbühren, U., Kleffmann, T., Legge, M., Poole, E. S., & Tate, W. P. (2007). A mammalian gene PEG10 expresses two reading frames by high efficiency -1 frameshifting in embryonic-associated tissues. Journal of Biological Chemistry, 282(52), 37359-37369.

Soleimanpour-Lichaei, H. R., Kühl, I., Gaisne, M., Passos, J. F., Wydro, M., Rorbach, J., … Tate, W., … Chrzanowska-Lightowlers, Z. (2007). mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG. Molecular Cell, 27, 745-757.

Poole, E. S., Young, D. J., Askarian-Amiri, M. E., Scarlett, D.-J. G., & Tate, W. P. (2007). Accommodating the bacterial decoding release factor as an alien protein among the RNAs at the active site of the ribosome. Cell Research, 17, 591-607.

Turner, P. R., Bourne, K., Garama, D., Carne, A., Abraham, W. C., & Tate, W. P. (2007). Production, purification and functional validation of human secreted amyloid precursor proteins for use as neuropharmacological reagents. Journal of Neuroscience Methods, 164, 68-74.

Williams, J. M., Guévremont, D., Mason-Parker, S. E., Luxmanan, C., Tate, W. P., & Abraham, W. C. (2007). Differential trafficking of AMPA and NMDA receptors during long-term potentiation in awake adult animals. Journal of Neuroscience, 27(51), 14171-14178.

Conference Contribution - Published proceedings: Abstract

Young, G., Bourne, K., Tate, W. P., & Williams, J. M. (2007). Regulation of N-methyl-D-asparate receptor subunits NR1 and NR2A expression in vitro. In J. G. Anson (Ed.), Proceedings of the 25th International Australasian Winter Conference on Brain Research. 25, (pp. 43). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2007Abstracts.pdf

Conference Contribution - Poster Presentation (not in published proceedings)

Bernhardt, H. S., & Tate, W. P. (2007, February). Transfer RNA building blocks for nanotechnology. Poster session presented at the Nano- and Bionano- Technology Quantum Transport and Quantum Functional Semiconductors (NBT-QT) Conference, Wellington, New Zealand.

Bernhardt, H. S., & Tate, W. P. (2007, February). Transfer RNA building blocks for nanotechnology. Poster session presented at the Third International Conference on Advanced Materials and Nanotechnology: AMN-3, Wellington, New Zealand.

Bernhardt, H. S., & Tate, W. P. (2007, March). Transfer RNA building blocks for nanotechnology. Poster session presented at the Supramolecular Chemistry and Nanoscience Conference, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Bernhardt, H., & Tate, W. P. (2007, August). Self-assembling transfer RNA has potential for nanoparticle arrays. Verbal presentation at the 17th Queenstown Molecular Biology Meeting, Queenstown, New Zealand.

Tate, W. (2007, April). Translational frameshifting: A vulnerable point in the biology of HIV-₁ or a mechanism shared with the human genome? Verbal presentation at the Webster Centre for Molecular Research in Infectious Diseases Symposium, Dunedin, New Zealand.

Tate, W. (2007, March). Serendipity in science: Showing how a research area can develop strategically from a fundamental study and discovery. Keynote presentation at the Faculty of Dentistry 3M Research Day, Dunedin, New Zealand.

2006

Journal - Research Article

Cridge, A. G., Major, L. L., Mahagaonkar, A. A., Poole, E. S., Isaksson, L. A., & Tate, W. P. (2006). Comparison of characteristics and function of translation termination signals between and within prokaryotic and eukaryotic organisms. Nucleic Acids Research, 34(7), 1959-1973. doi: 10.1093/nar/gkl074

Jacobs, G. H., Stockwell, P. A., Tate, W. P., & Brown, C. M. (2006). Transterm: Extended search facilities and improved integration with other databases. Nucleic Acids Research, 34(Database), D37-D40.

Journal - Research Other

Bernhardt, H. S., & Tate, W. P. (2006). Transfer RNA as a potential building block for nanotechnology. Chemistry in New Zealand, 70(1), 7-11.

Conference Contribution - Published proceedings: Abstract

Ballagh, I., Ireland, D., Mockett, B., Bourne, K., Tate, W., Williams, J., & Abraham, W. (2006). The effect of secreted-amyloid precursor protein on NMDA receptors in cultured rat hippocampal slices. New Zealand Medical Journal, 119(1234). Retrieved from http://journal.nzma.org.nz/journal/119-1234/1991/content.pdf

Conference Contribution - Poster Presentation (not in published proceedings)

Garama, D. J., Carne, A., Abraham, W. C., & Tate, W. P. (2006, August). The purification and investigation of secreted amyloid precursor proteins. Poster session presented at the 16th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand.

Taylor, C. J., Bourne, K., Tate, W. P., & Abraham, W. C. (2006, July). Secreted amyloid precursor protein-alpha regulates the induction of LTP in anesthetized rats. Poster session presented at the International Conference on Alzheimer's Disease and Related Disorders, Madrid, Spain.

Conference Contribution - Verbal presentation and other Conference outputs

Tate, W. P., Abraham, W. C., Turner, P. R., Bourne, K., Garama, D., Carne, A., Taylor, C., Ballagh, I., & Ireland, D. (2006, September). Production, purification and functional validation of human secreted amyloid precursor proteins as neuropharmacological agents. Verbal presentation at the 9th Asia Pacific International Molecular Biology Network Meeting, Kuala Lumpur, Malaysia.

2004

Chapter in Book - Research

Poole, E. S., Major, L. L., Cridge, A. G., & Tate, W. P. (2004). The mechanism of recoding in pro- and eukaryotes. In K. H. Nierhaus & D. N. Wilson (Eds.), Protein synthesis and ribosome structure: Translating the genome. (pp. 397-428). Weinheim, Germany: Wiley-VCH.

Journal - Research Article

Tate, W. P., & Poole, E. S. (2004). The ribosome: Lifting the veil from a fascinating organelle. BioEssays, 26, 582-588.

Mockett, B. G., Brooks, W. M., Tate, W. P., & Abraham, W. C. (2004). Dopamine D1/D5 receptor activation fails to initiate an activity-independent late-phase LTP in rat hippocampus. Brain Research, 1021, 92-100.

Conference Contribution - Poster Presentation (not in published proceedings)

Taylor, C. J., Turner, P. R., Tate, W. P., & Abraham, W. C. (2004, July). The contribution of secreted-amyloid precursor protein to the induction of long-term potentiation in anaesthetised rats. Poster session presented at the 9th International Conference on Alzheimer's Disease and Related Disorders, Philadelphia, Pennsylvania. Retrieved from http://www.nzma.org.nz/journal/116-1179/689/

2003

Journal - Research Article

Cridge, A. G., Poole, E. S., & Tate, W. P. (2003). The signal for stop in protein synthesis in eukaryotes: Evidence for a sequence element rather than a simple stop codon. New Zealand BioScience, 12, 37-38.

Turner, P. R., O'Connor, K., Tate, W. P., & Abraham, W. C. (2003). Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory. Progress in Neurobiology, 70, 1-32.

Poole, E. S., Askarian-Amiri, M. E., Major, L. L., McCaughan, K. K., Scarlett, D.-J. G., Wilson, D. N., & Tate, W. P. (2003). Molecular mimicry in the decoding of translational stop signals. Progress in Nucleic Acid Research & Molecular Biology, 74, 83-121.

Scarlett, D.-J. G., McCaughan, K. K., Wilson, D. N., & Tate, W. P. (2003). Mapping functionally important motifs SPF and GGQ of the decoding release factor RF2 to the Escherichia coli ribosome by hydroxyl radical footprinting. Journal of Biological Chemistry, 278(17), 15095-15104.

Williams, J. M., Guévremont, D., Kennard, J. T. T., Mason-Parker, S. E., Tate, W. P., & Abraham, W. C. (2003). Long-term regulation of N-methyl-_D-aspartate receptor subunits and associated synaptic proteins following hippocampal synaptic plasticity. Neuroscience, 118, 1003-1013.

Conference Contribution - Published proceedings: Abstract

Taylor, C., Turner, P., Tate, W., & Abraham, W. (2003). The contribution of secreted-amyloid precursor protein to the induction of long-term potentiation in anaesthetised rats. New Zealand Medical Journal, 116(1186). Retrieved from http://journal.nzma.org.nz/journal/116-1186/689/content.pdf

2002

Journal - Research Article

Jacobs, G. H., Rackham, O., Stockwell, P. A., Tate, W. P., & Brown, C. M. (2002). Transterm: a database of mRNAs and translational control elements. Nucleic Acids Research, 30, 310-311.

Major, L. L., Edgar, C. D., Yip, P. Y., Isaksson, L. A., & Tate, W. P. (2002). Tandem termination signals: Myth or reality. FEBS Letters, 514, 84-89.

Conference Contribution - Published proceedings: Full paper

Watts, M., Major, L. L., & Tate, W. P. (2002). Evolutionary optimisation of multi-layer perceptions for modelling protein synthesis termination signal efficiency. In D. B. Fogel, M. A. El-Sharkawi, X. Yao, G. Greenwood, H. Iba, P. Marrow & M. Shackleton (Eds.), The Congress on Evolutionary Computation (CEC) 2002. 1, (pp. 193-198). Piscataway, NJ: IEEE Press. [Full Paper]

2001

Journal - Research Article

Mansell, J. B., Guevremont, D., Poole, E. S., & Tate, W. P. (2001). A dynamic competition between release factor 2 and the tRNA^Sec decoding UGA at the recoding site of Escherichia coli formate dehydrogenase H. EMBO Journal, 20, 7284-7293.

Stenstrom, M. C., Haining, J., Major, L. L., Tate, W. P., & Isaksson, L. A. (2001). Codon bias at the 3'-side of the initiation codon is correlated with translation initiation efficiency in Escherichia coli. Gene, 263, 273-284.

Abraham, W. C., Mason-Parker, S. E., Bear, M. F., Webb, S. C., & Tate, W. P. (2001). Heterosynaptic metaplasticity in the hippocampus in vivo: A BCM-like modifiable threshold for LTP. PNAS, 98, 10924-10929.

Conference Contribution - Published proceedings: Full paper

Watts, M., Major, L. L., Kasabov, N. K., & Tate, W. P. (2001). Neural network analysis of protein termination signal efficiency. Proceedings of International Conference on Neural Information Processing. (pp. 975-980). China: ICONIP. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Brooks, W. M., Abraham, W. C., & Tate, W. P. (2001). Hippocampal NMDA and dopamine receptors: Do they synergistically support synaptic strengthening? International Journal of Neuroscience. 108, (pp. 233). [Abstract]

Sun, Q., Wickens, J., & Tate, W. P. (2001). Dopamine and glutamate effects on protein phosphorylation and gene expression in the rat striatum, in vitro. Proceedings of the 7th Triennial Meeting, International Basal Ganglia Society. (pp. 90). [Abstract]

Williams, J. M., Thompson, V. L., Guevremont, D., Abraham, W. C., Tate, W. P., & Nairn, A. C. (2001). Presynaptic protein synthesis in axon terminals isolated from adult rat cortex. Proceedings of International Australasian Winter Conference on Brain Research. 19. [Abstract]

Williams, J. M., Guevremont, D., Mason-Parker, S. E., Abraham, W. C., & Tate, W. P. (2001). Regulation of NMDA receptor subunit NR1 folloing synaptic activity. Molecular Mechanisms of Synaptic Function. 2(42). [Abstract]

Williams, J. M., Mason-Parker, S. E., Abraham, W. C., & Tate, W. P. (2001). Regulation of NMDA receptor subunit NR1 following synaptic activity. 11th Neuropharmacology Conference Molecular Mechanisms of Synaptic Function. (pp. 2.42). United Kingdom: Elzevier Science. [Abstract]

Thompson, V. L., Williams, J. M., & Tate, W. P. (2001). Synaptoneurosomes as a model for studying glutamate regulation of synaptic protein synthesis. International Journal of Neuroscience. 109, (pp. 201). [Abstract]

Williams, J. M., Thompson, V. L., Guevremont, D., Abraham, W. C., Tate, W. P., & Nairn, A. C. (2001). Protein synthesis in axon terminals isolated from adult rat cortex. 19th International Australasian Winter Conference on Brain and Research. 19, (pp. 40). Queenstown, New Zealand: Australasian Winter Conference on Brain and Research. [Abstract]

Williams, J. M., Thompson, V. L., Guévremont, D., Abraham, W. C., Tate, W. P., & Nairn, A. C. (2001). Presynaptic protein synthesis in axon terminals isolated from adult rat cortex. Society for Neuroscience Abstract. 27, (pp. 275.9). San Diego, USA: Society for Neuroscience. [Abstract]

2000

Journal - Research Article

Williams, J. M., Beckmann, A. M., Mason-Parker, S. E., Abraham, W. C., Wilce, P. A., & Tate, W. P. (2000). Sequential increase in Egr-1 and AP-1 DNA binding activity in the dentate gyrus following the induction of long-term potentiation. Molecular Brain Research, 77, 258-266.

Wilson, D. N., Guevremont, D., & Tate, W. P. (2000). The ribosomal binding and peptidyl-tRNA hydrolysis functions of Escherichia coli release factor 2 are linked through residue 246. RNA, 6, 1-10.

Jacobs, G. H., Stockwell, P. A., Schreiber, M. J., Tate, W. P., & Brown, C. M. (2000). Transterm: A database of messenger RNA components and signals. Nucleic Acids Research, 28, 293-295.

Askarian-Amiri, M. E., Pel, H. J., Guevremont, D., McCaughan, K. K., Poole, E. S., Sumpter, V. G., & Tate, W. P. (2000). Functional characterization of yeast mitochondrial release factor 1. Journal of Biological Chemistry, 275, 17241-17248.

Poole, E., & Tate, W. (2000). Release factors and their role as decoding proteins: Specificity and fidelity for termination of protein synthesis. Biochimica et Biophysica Acta: Gene Structure & Expression, 1493, 1-11.

Wilson, D. N., Dalphin, M. E., Pel, H. J., Major, L. L., Mansell, J. B., & Tate, W. P. (2000). Factor-mediated termination of protein synthesis: A welcome return to the mainstream of translation. The Ribosome: Structure, Function, Antibiotics & Cellular Interactions, 40, 495-508. Washington, D.C.: ASM Press.

Raymond, C., Thompson, V. L., Tate, W. P., & Abraham, W. C. (2000). Metabotropic glutamate receptors trigger homosynaptic protein synthesis to prolong long-term potentiation. Journal of Neuroscience, 20, 969-976.

Conference Contribution - Published proceedings: Abstract

Webb, S. C., Williams, J. M., Tate, W. P., & Abraham, W. C. (2000). Involvement of the cAMP cascade in the printing of hippocampal LTP by metabotropic glutamate receptors. Society for Neuroscience Abstract. 26, (pp. 361). USA: Society fo Neuroscience. [Abstract]

Sun, Q., Wickens, J., & Tate, W. P. (2000). Differential regulation of protein phosphorylation and gene expression by dopamine and glutamate in at striatal slices. Society for Neuroscience Absracts. (pp. 1). [Abstract]

McKinney, C. Z., & Tate, W. P. (2000). Regulated translational frameshifting in HIV-1. Proceedings of the University of Otago Medical School. 78, (pp. 12). [Abstract]

1999

Journal - Research Article

Scrimshaw, B. J., Faed, J. M., Tate, W. P., & Yun, K. (1999). Rapid identification of a 1555 A to G mutation in human mitochronical DNA implicated in aminoglycoside-induced ototoxicity. Journal of Human Genetics, 44, 388-390.

Brown, C. M., Jacobs, G. H., Schreiber, M. J., Magnum, J., McNaughton, J. C., Cambray, M., Futschik, M., Major, L. L., Rackham, O., Tate, W. P., … Stockwell, P. A., & Kasabov, N. K. (1999). Using bioinformatics to investigate post-transcriptional control of gene expression. New Zealand BioScience, 7, 11-12.

Scrimshaw, B. J., Faed, J. M., Tate, W. P., & Yun, K. (1999). The frequency in New Zealand of a mitochondrial DNA mutation (1555 A to G) associated with aminoglycoside-induced hearing loss. New Zealand Medical Journal, 112, 216-217.

Tate, W. P., Mansell, J. B., Mannering, S. A., Irvine, J., Major, L. L., & Wilson, D. N. (1999). UGA: A dual signal for "stop" and for recoding in protein synthesis. Biochemistry (Moscow), 64, 1342-1353.

Dalphin, M. E., Stockwell, P. A., Tate, W. P., & Brown, C. M. (1999). TransTerm, the translational signal database, extended to include full coding sequences and untranslated regions. Nucleic Acids Research, 27, 293-294.

Crawford, D.-J. G., Ito, K., Nakamura, Y., & Tate, W. P. (1999). Indirect regulation of translational termination efficiency at highly expressed genes and recoding sites by the factor recycling function of Escherichia coli release factor RF3. EMBO Journal, 18, 727-732.

Conference Contribution - Published proceedings: Abstract

Sun, Q., Tate, W. P., & Wickens, J. (1999). Interactions of dopamine and glutamate signalling pathways for protein phosphorylation in the striatum: A possible explanation for the establishment of LTD or LDP. International Journal of Neuroscience. 97, (pp. 265). [Abstract]

1998

Journal - Research Article

McCaughan, K. K., Poole, E. S., Pel, H. J., Mansell, J., Mannering, S. A., & Tate, W. P. (1998). Efficient in vitro translational termination in Escherichia coli is constrained by the orientations of the release factor, stop signal and peptidyl-tRNA within the termination complex. Biological Chemistry, 379(7), 857-866.

Poole, E. S., Major, L. L., Mannering, S. A., & Tate, W. P. (1998). Translational termination in Escherichia coli: three bases following the stop codon crosslink to release factor 2 and affect the decoding efficiency of UGA-containing signals. Nucleic Acids Research, 26, 954-960.

Williams, J. M., Thompson, V. L., Mason-Parker, S. E., Abraham, W. C., & Tate, W. P. (1998). Synaptic activity-dependent modulation of mitochondrial gene expression in the rat hippocampus. Molecular Brain Research, 60, 50-56.

Williams, J. M., Mason-Parker, S. E., Abraham, W. C., & Tate, W. P. (1998). Biphasic changes in the levels of N-methyl-D-aspartate receptor-2 subunits correlate with the induction and persistence of long-term potentiation. Molecular Brain Research, 60, 21-27.

Dalphin, M. E., Brown, C. M., Stockwell, P. A., & Tate, W. P. (1998). The translational signal database, TransTerm, is now a relational database. Nucleic Acids Research, 26, 335-337.

Trotman, C. N. A., Coleman, M., Jellie, A.-M., Shieffelbien, D. C., & Tate, W. P. (1998). Haemoglobin: a primordial role preserved in diapause? Archiv für Hydrobiologie, 52, 441-449.

Irvine, J., Horsfield, J. A., McKinney, C. Z., & Tate, W. P. (1998). A novel strategy to interfere with human immunodeficiency virus type 1 propagation. New Zealand Medical Journal, 111, 222-224.

Pel, H. J., Moffat, J. G., Ito, K., Nakamura, Y., & Tate, W. P. (1998). Escherichia coli release factor 3: Resolving the paradox of a typical G protein structure and atypical function with guanine nucleotides. RNA, 4, 47-54.

Conference Contribution - Published proceedings: Abstract

Williams, J. M., Mason-Parker, S. E., Abraham, W. C., & Tate, W. P. (1998). Rapid increase in N-methyl-D-aspartate receptor subunit NR2B following long-term potentiation. International Journal of Neuroscience. 94, (pp. 108). [Abstract]

1997

Journal - Research Article

Abraham, W. C., Logan, B., Thompson, V. L., Williams, J. M., & Tate, W. P. (1997). Sequence-independent effects of phosphorothioated oligonucleotides on synaptic transmission and excitability in the hippocampus in vivo. Neuropharmacology, 36, 345-352.

Abraham, W. C., & Tate, W. P. (1997). Metaplasticity: A new vista across the field of synaptic plasticity. Progress in Neurobiology, 52, 303-323.

Dalphin, M. E., Brown, C. M., Stockwell, P. A., & Tate, W. P. (1997). The translational signal database, TransTerm: more organisms, complete genomes. Nucleic Acids Research, 25, 246-247.

Poole, E. S., Brimacombe, R., & Tate, W. P. (1997). Decoding the translational termination signal: the polypeptide chain release factor in Escherichia coli crosslinks to the base following the stop codon. RNA, 3, 974-982.

Conference Contribution - Published proceedings: Abstract

Matthews, C., Jellie, A.-M., Tate, W. P., & Trotman, C. N. A. (1997). Ancient and recent duplication events in Artemia provide a model for intron positional stability. Proceedings of the Symposium on Exon/Intron Structure. (pp. S19). [Abstract]

Trotman, C. N. A., Coleman, M., Jellie, A.-M., Matthews, C. M., Shieffelbien, D. C., Tate, W. P., & Vandenberg, C. J. (1997). Heamoglobin: A primordial role preserved in diapause? Proceedings of the Symposium on Diapause in the Crustacea. (pp. 35). [Abstract]

Williams, J. S., Mason-Parker, S. E., Abraham, W. C., & Tate, W. P. (1997). Rapid and persistent elevation in the N-methyl-D-aspartate receptor subunit NR2B folowing long-term potentiation. Society for Neuroscience Abstracs. 23, (pp. 1175). [Abstract]

Williams, J. M., Mason-Parker, S. E., Abraham, W. C., & Tate, W. P. (1997). NMDA receptor subunit composition and phosphorylation following long-term potentiation. International Journal of Neuroscience. 89, (pp. 91). [Abstract]

Webb, S. C., Williams, J. M., Tate, W. P., Mason-Parker, S. E., & Abraham, W. C. (1997). Expression of elongation factor-2 during the maintenance of long-term potentiation. International Journal of Neuroscience. 89, (pp. 92). [Abstract]

Williams, J. M., Mason-Parker, S. E., Abraham, W. C., & Tate, W. P. (1997). Rapid and persistent elevation in N-methyl-D-aspartate receptor subunit NR2B following long-term potentiation. Society for Neuroscience Abstract. 23, (pp. 1175). San Diego, USA: Society for Neuroscience. [Abstract]

Ross, M. F., Pel, H. J., & Tate, W. P. (1997). Cloning and expression of the yeast cytosolic and mitochondrial release factors. Proceedings of the University of Otago Medical School. 75, (pp. 25). Dunedin: University of Otago. [Abstract]

Matthews, C. M., Jellie, A.-M., Tate, W. P., & Trotman, C. N. A. (1997). Evolutionary history of the T and C polymer introns of Artemia haemoglobin genes. Proceedings of the University of Otago Medical School. 75, (pp. 5-6). Dunedin. [Abstract]

Cheesman, E. T., Pel, H. J., & Tate, W. P. (1997). Isolation and characterisation of the human mitochondrial release factor, a potential deafness locus on chromosome 4. Proceedings of the University of Otago Medical School. 75(1), (pp. 10). Dunedin: University of Otago. [Abstract]

Major, L. L. M., & Tate, W. P. (1997). Tandem translational termination signals in E coli: Are two stops better than one? Proceedings of the University of Otago Medical School. 75, (pp. 16). Dunedin: University of Otago. [Abstract]

1996

Chapter in Book - Research

Tate, W. P., Dalphin, M. E., Pel, H. J., & Mannering, S. A. (1996). Decoding efficiencies of translational stop signals: a new facet of cellular regulation. In J. K. Setlow (Ed.), Genetic Engineering, Principles and Methods, Volume 18. (pp. 157-182). New York: Plenum Press.

Journal - Research Article

Tate, W. P., Poole, E., Dalphin, M. E., Major, L. L. M., Crawford, D.-J. G., & Mannering, S. A. (1996). The translational stop signal: Codon with a context, or extended factor recognition element? Biochimie, 78(11-12), 945-952.

Jellie, A. M., Tate, W. P., & Trotman, C. N. (1996). Evolutionary history of introns in a multi-domain globin gene. Journal of Molecular Evolution, 42, 641-647.

Tate, W. P., & Mannering, S. A. (1996). Three, four or more: the translational stop signal at length. Molecular Microbiology, 21, 213-219.

Tate, W. P., Poole, E., & Mannering, S. A. (1996). Hidden infidelities of the translational stop signal. Progress in Nucleic Acid Research & Molecular Biology, 52, 293-336.

Dalphin, M. E., Brown, C., Stockwell, P. A., & Tate, W. P. (1996). TransTerm: a database of translational signals. Nucleic Acids Research, 24, 216-218.

Major, L. L., Poole, E., Dalphin, M. E., Mannering, S. A., & Tate, W. P. (1996). Is the in frame termination signal of the Escherichia coli release factor-2 frameshift site weakened by a particularly poor context? Nucleic Acids Research, 24, 2673-2678.

Conference Contribution - Published proceedings: Abstract

Pel, H. J., Bolotin-Fukuhara, M., & Tate, W. P. (1996). From yeast to man: A yeast model system for the study of human aminoglycoside induced deafness. Proceedings of the University of Otago Medical School. 74(3), (pp. 44). Dunedin: University of Otago. [Abstract]

Irvine, J., Horsfield, J. A., & Tate, W. P. (1996). Factors influencing +1 and -1 frameshifting on mammalian ribosomes. Proceedings of the University of Otago Medical School. 74(1), (pp. 8). Dunedin: University of Otago. [Abstract]

1995

Journal - Research Article

Tate, W. P., Poole, E. S., Horsfield, J. A., Mannering, S. A., Brown, C. M., Moffat, J. G., Dalphin, M. E., … Major, L. L., & Wilson, D. N. (1995). Translational termination efficiency in both bacteria and mammals is regulated by the base following the stop codon. Biochemistry & Cell Biology, 73, 1095-1103. doi: 10.1139/o95-118

Curran, J. F., Poole, E., Tate, W. P., & Gross, B. L. (1995). Selection of aminoacyl-tRNAs at sense codons: the size of the tRNA variable loop determines whether the immediate 3' nucleotide to the codon has a context effect. Nucleic Acids Research, 23, 4104-4108.

Tate, W. P. (1995). Genetic code revisited: a substratum of cellular regulation revealed. New Zealand BioScience, 3, 22-25.