Contact Details
- Phone
- 64 3 479 7832
- hod.biochemistry@otago.ac.nz
University Links
- Position
- Professor and Head of Department
- Department
- Department of Biochemistry
- Qualifications
- BSc(Hons) PhD
- Research summary
- Evolution, development, and genome evolution
Research
Evolution and development, genome evolution
Genetic studies have helped us to understand the molecular control of development in a small number of model systems. In Drosophila melanogaster and Caenorhabditis elegans, for example, we can trace the molecular events that pattern specific body parts all the way back to the fertilised egg. What is unclear is how these patterning processes change over evolutionary time to give us the diversity of morphology we see in organisms today.
Our lab aims to understand the molecular basis of morphological evolution by studying how the developmental pathways that regulate embryogenesis evolve to produce different animal morphologies. To study this we use two model systems, the Honeybee (Apis mellifera) and a Rotifer (Brachionus plicatilis).
The evolution of developmental pathways
To understand and model the evolution of developmental pathways we need to study how evolutionary processes affect the complex interactions of genes and proteins that pattern embryos. One of the best model systems for understanding pattern formation is segmentation in the fruit fly Drosophila melanogaster. Twenty years of study of this system has lead to an almost complete understanding of how genes and their product produce the segments of Drosophila. We are studying how this system has evolved by looking at the same segmentation process in the Honeybee. Honeybee segmentation is homologous to segmentation in Drosophila, uses many of the same genes, but is different in its morphological and molecular details. Using RNAi and transgenic Drosophila we are trying to understand how these molecular and morphological changes have come about. This study should give us a better understanding of the way in which developmental processes evolved and will perhaps lead to a predictive theory of the evolution of development.
Deep homology and the evolution of animals
Little is known about the genetic control of development in animals other than the well-studied genetic model systems Drosophila, Caenorhabditis, Zebrafish and mouse. One group of animals that are poorly researched are the Lophotrochozoa, a group of animal phyla including annelids, molluscs, platyhelminths, rotifers and others. Without understanding how these animals regulate development we are unable to develop a clear picture of the evolutionary history of animals. To study the genetic control of development in the Lophotrochozoa we are using a Rotifer, Brachionus plicatilis, as a model system. Rotifers are tiny aquatic animals that are easy to grow in the laboratory and have a short generation time. We have developed technique to examine gene expression and function and are using these to understand development in this animal.
These projects are funded by a Royal Society of New Zealand Marsden Grant and a University of Otago Research Grant.
Awards
- Peter Dearden
2016, Best Research Paper of the Year by a BMS Researcher - Peter Dearden
2014, Genetics Society of AustralAsia Ross Crozier Medal
For outstanding contributions to genetics - Peter Dearden
2014, Callaghan Medal for science communication
For the outreach activities of Genetics Otago that he helped form and his involvement in communicating his genetics research on honey bees with the beekeeping industry and the public. - Peter Dearden and Dr Elizabeth Duncan
2010, Otago School of Medical Sciences Best Paper Award
Publications
Fèvre, D. P., & Dearden, P. K. (2024). Influence of nutrition on honeybee queen egg-laying. Apidologie, 55, 53. doi: 10.1007/s13592-024-01097-1 Journal - Research Other
Inwood, S. N., Harrop, T. W. R., Shields, M. W., Goldson, S. L., & Dearden, P. K. (2024). Immune system modulation & virus transmission during parasitism identified by multi-species transcriptomics of a declining insect biocontrol system. BMC Genomics, 25, 311. doi: 10.1186/s12864-024-10215-3 Journal - Research Article
Inwood, S. N., Harrop, T. W. R., Goldson, S. L., & Dearden, P. K. (2023, August-September). Transmission of a novel virus in a declining insect biocontrol system. Verbal presentation at the He taonga tuku iho: Queenstown Molecular Biology (QMB) Bioprotection Aotearoa Satellite, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Dainty, K. R., Inwood, S., Goldson, S. L., & Dearden, P. K. (2023, August-September). Predicting successful biocontrol: What we can learn from Microctonus hyperodae genomics. Verbal presentation at the He taonga tuku iho: Queenstown Molecular Biology (QMB) Bioprotection Aotearoa Satellite, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Dearden, P. K., Inwood, S., & Skelly, J. (2023, August-September). How might we refresh biocontrol agents? Verbal presentation at the He taonga tuku iho: Queenstown Molecular Biology (QMB) Bioprotection Aotearoa Satellite, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
2024
Journal - Research Article
Inwood, S. N., Harrop, T. W. R., Shields, M. W., Goldson, S. L., & Dearden, P. K. (2024). Immune system modulation & virus transmission during parasitism identified by multi-species transcriptomics of a declining insect biocontrol system. BMC Genomics, 25, 311. doi: 10.1186/s12864-024-10215-3
Journal - Research Other
Fèvre, D. P., & Dearden, P. K. (2024). Influence of nutrition on honeybee queen egg-laying. Apidologie, 55, 53. doi: 10.1007/s13592-024-01097-1
2023
Journal - Research Article
Guhlin, J., Le Lec, M. F., Wold, J., Koot, E., Winter, D., Biggs, P. J., … Urban, L., Foster, Y., … Robertson, F. E., Robertson, B. C., Gemmell, N. J., … Dearden, P. K. (2023). Species-wide genomics of kākāpō provides tools to accelerate recovery. Nature Ecology & Evolution. Advance online publication. doi: 10.1038/s41559-023-02165-y
Mortensen, A. N., Jochym, M., Dearden, P. K., & Sainsbury, J. P. (2023). Old strategies as modern solutions, shook swarming reduced Varroa destructor infestation rates of managed honey bee, Apis mellifera, colonies. Journal of Apicultural Research. Advance online publication. doi: 10.1080/00218839.2023.2243044
Inwood, S. N., Skelly, J., Guhlin, J. G., Harrop, T. W. R., Goldson, S. L., & Dearden, P. K. (2023). Chromosome-level genome assemblies of two parasitoid biocontrol wasps reveal the parthenogenesis mechanism and an associated novel virus. BMC Genomics, 24, 440. doi: 10.1186/s12864-023-09538-4
Cullen, G., Gilligan, J. B., Guhlin, J. G., & Dearden, P. K. (2023). Germline progenitors and oocyte production in the honeybee queen ovary. Genetics. Advance online publication. doi: 10.1093/genetics/iyad138
West, A. G., Digby, A., Santure, A. W., Guhlin, J. G., Dearden, P., Kākāpō Recovery Team, … Urban, L. (2023). Capturing species-wide diversity of the gut microbiota and its relationship with genomic variation in the critically endangered kākāpō. Molecular Ecology. Advance online publication. doi: 10.1111/mec.16999
West, A. G., Digby, A., Kākāpō Recovery Team, Kākāpō Aspergillosis Research Consortium, including Dearden, P. K., Gemmell, N. J., Guhlin, J., Le Lec, M., Quinones Mateu, M., and Taylor, M. D. (2023). The mycobiota of faeces from the critically endangered kākāpō and associated nest litter. New Zealand Journal of Zoology. Advance online publication. doi: 10.1080/03014223.2023.2170428
Digby, A., Eason, D., Catalina, A., Lierz, M., Galla, S., Urban, L., Le Lec, M. F., Guhlin, J., Steeves, T. E., Dearden, P. K., … Kākāpō Recovery Team. (2023). Hidden impacts of conservation management on fertility of the critically endangered kākāpō. PeerJ, 11, e14675. doi: 10.7717/peerj.14675
Lovegrove, M. R., Dearden, P. K., & Duncan, E. J. (2023). Honeybee queen mandibular pheromone induces a starvation response in Drosophila melanogaster. Insect Biochemistry & Molecular Biology, 154, 103908. doi: 10.1016/j.ibmb.2023.103908
Inwood, S., Harrop, T. W. R., & Dearden, P. K. (2023). The venom composition and parthenogenesis mechanism of the parasitoid wasp Microctonus hyperodae, a declining biocontrol agent. Insect Biochemistry & Molecular Biology, 153, 103897. doi: 10.1016/j.ibmb.2022.103897
Zawierucha, K., Stec, D., Dearden, P. K., & Shain, D. H. (2023). Two new tardigrade genera from New Zealand’s Southern Alp glaciers display morphological stasis and parallel evolution. Molecular Phylogenetics & Evolution, 178, 107634. doi: 10.1016/j.ympev.2022.107634
Journal - Research Other
Wold, J. R., Guhlin, J. G., Dearden, P. K., Santure, A. W., & Steeves, T. E. (2023). The promise and challenges of characterising genome-wide structural variants: A case study in a critically endangered parrot. Molecular Ecology Resources. Advance online publication. doi: 10.1111/1755-0998.13783
Conference Contribution - Published proceedings: Abstract
Hawkes, M. K. N., Dearden, P. K., Gemmell, N. J., & Kenny, N. J. (2023). Evaluating the impacts of climate change at a cellular resolution through comparative single cell sequencing of kuku (green-lipped mussels). Proceedings of the Genetics Otago (GO) Annual Symposium & Workshops. Retrieved from https://blogs.otago.ac.nz/go
Cridge, A., Hyink, O., Armstrong, K., Harrop, T., & Dearden, P. (2023). Bees as biosecurity biomonitors: Exotic plant detection and identification to monitor plant invasions. Proceedings of the 1st Australian & New Zealand Environmental DNA (eDNA) Conference: Innovation & Application. Retrieved from https://ednaconference.com.au
Guhlin, J., Keddell, P., & Dearden, P. (2023). Reannotating 282 genomes: The hymenopteran unified gene set. Proceedings of the eResearch NZ Conference. (pp. 26). Retrieved from www.eresearchnz2023.org.nz
Conference Contribution - Verbal presentation and other Conference outputs
Inwood, S. N., Harrop, T. W. R., Goldson, S. L., & Dearden, P. K. (2023, August-September). Transmission of a novel virus in a declining insect biocontrol system. Verbal presentation at the He taonga tuku iho: Queenstown Molecular Biology (QMB) Bioprotection Aotearoa Satellite, Queenstown, New Zealand.
Dainty, K. R., Inwood, S., Goldson, S. L., & Dearden, P. K. (2023, August-September). Predicting successful biocontrol: What we can learn from Microctonus hyperodae genomics. Verbal presentation at the He taonga tuku iho: Queenstown Molecular Biology (QMB) Bioprotection Aotearoa Satellite, Queenstown, New Zealand.
Dearden, P. K., Inwood, S., & Skelly, J. (2023, August-September). How might we refresh biocontrol agents? Verbal presentation at the He taonga tuku iho: Queenstown Molecular Biology (QMB) Bioprotection Aotearoa Satellite, Queenstown, New Zealand.
Delargy, E., & Dearden, P. K. (2023, August). Time to grow up: Validation of the timer-gene segmentation hypothesis in the honeybee. Verbal presentation at the Queenstown Molecular Biology (QMB) Genomics Satellite, Queenstown, New Zealand.
Guhlin, J. G., & Dearden, P. K. (2023, August-September). Species-wide genomics of kākāpō provides transformational tools to accelerate recovery. Verbal presentation at the He taonga tuku iho: Queenstown Molecular Biology (QMB) Bioprotection Aotearoa Satellite, Queenstown, New Zealand.
Dearden, P. (2023, September). Adventures in insect plasticity and sociality. Verbal presentation at the Company of Biologists Development Journal Meeting: Unconventional and emerging experimental organisms in cell and developmental biology, Dorking, UK.
2022
Journal - Research Article
Winter, D. J., Weir, B. S., Glare, T., Rhodes, J., Perrott, J., Fisher, M. C., … Dearden, P. K., & Cox, M. P. (2022). A single fungal strain was the unexpected cause of a mass aspergillosis outbreak in the world’s largest and only flightless parrot. iScience, 25, 105470. doi: 10.1016/j.isci.2022.105470
Shain, D. H., Iakovenko, N. S., Cridge, A. G., Novis, P. M., Plášek, V., & Dearden, P. K. (2022). Microinvertebrate colonization of New Zealand’s thermally extreme environments. Evolutionary Biology, 49, 414-423. doi: 10.1007/s11692-022-09578-w
Karunaraj, P., Tidswell, O., Duncan, E. J., Lovegrove, M. R., Jefferies, G., Johnson, T. K., Beck, C. W., & Dearden, P. K. (2022). Noggin proteins are multifunctional extracellular regulators of cell signaling. Genetics, 221(1), iyac049. doi: 10.1093/genetics/iyac049
Taylor, S. E., & Dearden, P. K. (2022). The Nasonia pair-rule gene regulatory network retains its function over 300 million years of evolution. Development, 149, dev199632. doi: 10.1242/dev.199632
Palmer, S., Dearden, P. K., Mercier, O. R., King-Hunt, A., & Lester, P. J. (2022). Gene drive and RNAi technologies: A bio-cultural review of next-generation tools for pest wasp management in New Zealand. Journal of the Royal Society of New Zealand, 52(5), 508-525. doi: 10.1080/03036758.2021.1985531
Journal - Research Other
Dearden, P. K. (2022). Evolution: Hidden homologies may underpin the diversity of arthropods. Current Biology, 32, R916-R918. doi: 10.1016/j.cub.2022.07.040
Duncan, E. J., Cunningham, C. B., & Dearden, P. K. (2022). Phenotypic plasticity: What has DNA methylation got to do with it? Insects, 13(2), 110. doi: 10.3390/insects13020110
Conference Contribution - Published proceedings: Abstract
Inwood, S. N., Skelly, J. G., & Dearden, P. K. (2022). Genomic insights into the failing biocontrol agent Microtonus hyperodae. Proceedings of the ComBio Conference. (pp. 106). Retrieved from https://combio.org.au/combio2022/
Cullen, G. R., Gilligan, J. B., & Dearden, P. K. (2022). Division clusters: Evidence for an unexpected mode of oogenesis in Apis mellifera. Proceedings of the ComBio Conference. (pp. 80). Retrieved from https://combio.org.au/combio2022/
Gilligan, J. B., & Dearden, P. K. (2022). Steps towards implementing a gene drive for invasive wasp species. Proceedings of the ComBio Conference. (pp. 39). Retrieved from https://combio.org.au/combio2022/
Smith-Beech, A. I. S., Delargy, E., Dearden, P. K., Lim, C. S., & Wilbanks, S. M. (2022). Phycourobilin and the evolution of the Florideophyte phycobilisome. Proceedings of the International Society of Photosynthesis Research (ISPR) 18th International Congress on Photosynthesis Research. (pp. 276). Retrieved from https://www.ps2022.nz
2021
Journal - Research Article
Petersen, G. E. L., Fennessy, P. F., & Dearden, P. K. (2021). Management tools for genetic diversity in an isolated population of the honeybee (Apis mellifera) in New Zealand. Animal Production Science, 61, 1856-1862. doi: 10.1071/An21102
McCulloch, G. A., Guhlin, J., Dutoit, L., Harrop, T. W. R., Dearden, P. K., & Waters, J. M. (2021). Genomic signatures of parallel alpine adaptation in recently-evolved flightless insects. Molecular Ecology, 30, 6677-6686. doi: 10.1111/mec.16204
Dussex, N., van der Valk, T., Morales, H. E., Wheat, C. W., Díez-del-Molino, D., von Seth, J., Foster, Y., … Le Lec, M. F., Dearden, P. K., … Knapp, M., Gemmell, N. J., Robertson, F., … Robertson, B. C., & Dalén, L. (2021). Population genomics of the critically endangered kākāpō. Cell Genomics, 1, 100002. doi: 10.1016/j.xgen.2021.100002
Leask, M., Lovegrove, M., Romeril, A., Duncan, E., & Dearden, P. (2021). Evolution and genomic organization of the insect sHSP gene cluster and coordinate regulation in phenotypic plasticity. BMC Ecology & Evolution, 21, 154. doi: 10.1186/s12862-021-01885-8
Shain, D., Novis, P. M., Cridge, A. G., Zawierucha, K., Geneva, A. J., & Dearden, P. K. (2021). Five animal phyla in glacier ice reveal unprecedented biodiversity in New Zealand's Southern Alps. Scientific Reports, 11(1), 3898. doi: 10.1038/s41598-021-83256-3
McCulloch, G. A., Foster, B. J., Dutoit, L., Harrop, T. W. R., Guhlin, J., Dearden, P. K., & Waters, J. M. (2021). Genomics reveals widespread ecological speciation in flightless insects. Systematic Biology, 70(5), 863-876. doi: 10.1093/sysbio/syaa094
Lamichhane, R., Munro, F., Harrop, T. W. R., de la Harpe, S. M., Dearden, P. K., Vernall, A. J., McCall, J. L., & Ussher, J. E. (2021). Human liver-derived MAIT cells differ from blood MAIT cells in their metabolism and response to TCR-independent activation. European Journal of Immunology, 51, 879-892. doi: 10.1002/eji.202048830
Journal - Research Other
Ambler, J., Diallo, A. A., Dearden, P. K., Wilcox, P., Hudson, M., & Tiffin, N. (2021). Including digital sequence data in the Nagoya Protocol can promote data sharing. Trends in Biotechnology, 39(2), 116-125. doi: 10.1016/j.tibtech.2020.06.009
Conference Contribution - Published proceedings: Abstract
Dearden, P. (2021). Gene drives for pest control: Panacea or painful problem? Proceedings of the Australia & New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART): Openness in Animal Research. (pp. 99-112). Retrieved from https://anzccart.org.nz/anzccart-conference
West, A. G., Digby, A., Santure, A. W., Le Lec, M. F., Ghulin, J., Dearden, P. K., … Urban, L. (2021). A genome-wide association study of the gut microbiota in the critically endangered kākāpō. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 252). Retrieved from https://www.faobmb2021.org
West, A. G., Digby, A., Santure, A. W., Ghulin, J., Dearden, P. K., Taylor, M. W., & Urban, L. (2021). Capturing species-wide diversity of the gut microbiota and its relationship with genomic variation in the critically endangered kākāpō. Proceedings of the Genetics Otago (GO) Annual Symposium. Retrieved from https://blogs.otago.ac.nz/go
2020
Journal - Research Article
Lovegrove, M. R., Knapp, R. A., Duncan, E. J., & Dearden, P. K. (2020). Drosophila melanogaster and worker honeybees (Apis mellifera) do not require olfaction to be susceptible to honeybee queen mandibular pheromone. Journal of Insect Physiology, 127, 104154. doi: 10.1016/j.jinsphys.2020.104154
Harrop, T. W. R., Guhlin, J., McLaughlin, G. M., Permina, E., Stockwell, P., Gilligan, J., Le Lec, M. F., Gruber, M. A. M., … Lovegrove, M., … Dearden, P. K. (2020). High-quality assemblies for three invasive social wasps from the Vespula genus. Genes Genomes Genetics, 10, 3479-3488. doi: 10.1534/g3.120.401579
Lester, P. J., Bulgarella, M., Baty, J. W., Dearden, P. K., Guhlin, J., & Kean, J. M. (2020). The potential for a CRISPR gene drive to eradicate or suppress globally invasive social wasps. Scientific Reports, 10, 12398. doi: 10.1038/s41598-020-69259-6
Harrop, T. W. R., Le Lec, M. F., Jauregui, R., Taylor, S. E., Inwood, S. N., van Stijn, T., … Skelly, J., … Dearden, P. K. (2020). Genetic diversity in invasive populations of Argentine stem weevil associated with adaptation to biocontrol. Insects, 11(7), 441. doi: 10.3390/insects11070441
Duncan, E. J., Leask, M. P., & Dearden, P. K. (2020). Genome architecture facilitates phenotypic plasticity in the honeybee (Apis mellifera). Molecular Biology & Evolution, 37(7), 1964-1978. doi: 10.1093/molbev/msaa057
Petersen, G. E. L., Fennessy, P. F., Van Stijn, T. C., Clarke, S. M., Dodds, K. G., & Dearden, P. K. (2020). Genotyping-by-sequencing of pooled drone DNA for the management of living honeybee (Apis mellifera) queens in commercial beekeeping operations in New Zealand. Apidologie, 51, 545-556. doi: 10.1007/s13592-020-00741-w
Oliphant, A., Hawkes, M. K. N., Cridge, A. G., & Dearden, P. K. (2020). Transcriptomic characterisation of neuropeptides and their putative cognate G protein-coupled receptors during late embryo and stage-1 juvenile development of the Aotearoa-New Zealand crayfish, Paranephrops zealandicus. General & Comparative Endocrinology, 292, 113443. doi: 10.1016/j.ygcen.2020.113443
Journal - Research Other
Inwood, S. N., McLaughlin, G. M., Buckley, T. R., Cox, M. P., Handley, K. M., Steeves, T. E., … Dearden, P. K. (2020). Opportunities for modern genetic technologies to maintain and enhance Aotearoa New Zealand’s bioheritage. New Zealand Journal of Ecology, 44(2), 3413. doi: 10.20417/nzjecol.44.22
Hudson, M., Garrison, N. A., Sterling, R., Caron, N. R., Fox, K., Yracheta, J., … Wilcox, P., … Dearden, P. K., … Russo Carroll, S. (2020). Rights, interests and expectations: Indigenous perspectives on unrestricted access to genomic data. Nature Reviews Genetics, 21, 377-384. doi: 10.1038/s41576-020-0228-x
Petersen, G. E. L., Fennessy, P. F., Amer, P. R., & Dearden, P. K. (2020). Designing and implementing a genetic improvement program in commercial beekeeping operations. Journal of Apicultural Research, 59(4), 638-647. doi: 10.1080/00218839.2020.1715583
2019
Chapter in Book - Research
Dearden, P. K. (2019). Hourglass or twisted ribbon? In W. Tworzydlo & S. M. Bilinski (Eds.), Evo-Devo: Non-model species in cell developmental biology: Results and problems in cell differentiation. (pp. 21-29). Cham, Switzerland: Springer. doi: 10.1007/978-3-030-23459-1_2
Cridge, A. G., Dearden, P. K., & Brownfield, L. R. (2019). The developmental hourglass in the evolution of embryogenesis. In L. N. de la Rosa & G. Müller (Eds.), Evolutionary developmental biology: A reference guide. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-33038-9
Journal - Research Article
Lamichhane, R., Schneider, M., de la Harpe, S. M., Harrop, T. W. R., Hannaway, R. F., Dearden, P. K., Kirman, J. R., Tyndall, J. D. A., Vernall, A. J., & Ussher, J. E. (2019). TCR- or cytokine-activated CD8+ mucosal-associated invariant T cells are rapid polyfunctional effectors that can coordinate immune responses. Cell Reports, 28(12), 3061-3076.e5. doi: 10.1016/j.celrep.2019.08.054
Lovegrove, M. R., Dearden, P. K., & Duncan, E. J. (2019). Ancestral hymenopteran queen pheromones do not share the broad phylogenetic repressive effects of honeybee queen mandibular pheromone. Journal of Insect Physiology, 119, 103968. doi: 10.1016/j.jinsphys.2019.103968
McCulloch, G. A., Oliphant, A., Dearden, P. K., Veale, A. J., Ellen, C. W., & Waters, J. M. (2019). Comparative transcriptomic analysis of a wing-dimorphic stonefly reveals candidate wing loss genes. EvoDevo, 10, 21. doi: 10.1186/s13227-019-0135-4
Taylor, S. E., Tuffery, J., Bakopoulos, D., Lequeux, S., Warr, C. G., Johnson, T. K., & Dearden, P. K. (2019). The torso-like gene functions to maintain the structure of the vitelline membrane in Nasonia vitripennis, implying its co-option into Drosophila axis formation. Biology Open, 8(9), bio046284. doi: 10.1242/bio.046284
McCulloch, G. A., Foster, B. J., Dutoit, L., Ingram, T., Hay, E., Veale, A. J., Dearden, P. K., & Waters, J. M. (2019). Ecological gradients drive insect wing loss and speciation: The role of the alpine treeline. Molecular Ecology, 28, 3141-3150. doi: 10.1111/mec.15114
Panfilio, K. A., Vargas Jentzsch, I. M., Benoit, J. B., Erezyilmaz, D., Suzuki, Y., Colella, S., … Duncan, E. J., … Cridge, A. G., … Dearden, P. K., … Leask, M., … Lovegrove, M. R., … Tidswell, O., … Richards, S. (2019). Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome. Genome Biology, 20, 64. doi: 10.1186/s13059-019-1660-0
Skelly, J., Pushparajan, C., Duncan, E. J., & Dearden, P. K. (2019). Evolution of the Torso activation cassette, a pathway required for terminal patterning and moulting. Insect Molecular Biology, 28(3), 392-408. doi: 10.1111/imb.12560
Journal - Research Other
McLaughlin, G., & Dearden, P. K. (2019). Invasive insects: Management methods explored. Journal of Insect Science, 19(5), 17. doi: 10.1093/jisesa/iez085
Guerrero, F. D., Bendele, K. G., Ghaffari, N., Guhlin, J., Gedye, K. R., Lawrence, K. E., Dearden, P. K., Harrop, T. W. R., … Tompkins, D. M. (2019). The Pacific Biosciences de novo assembled genome dataset from a parthenogenetic New Zealand wild population of the longhorned tick, Haemaphysalis longicornis Neumann, 1901 [Data article]. Data in Brief, 27, 104602. doi: 10.1016/j.dib.2019.104602
Veale, A. J., Dearden, P. K., & Waters, J. M. (2019). First complete mitochondrial genome of a Gripopterygid stonefly from the sub-order Antarctoperlaria: Zelandoperla fenestrata. Mitochondrial DNA Part B, 4(1), 886-888. doi: 10.1080/23802359.2018.1546130
Al-Jiab, R. A., Gillum, J., Alexander, A., Tompkins, D. M., Phillips, C. B., Dearden, P. K., & Gemmell, N. J. (2019). The complete mitogenome sequence of the agricultural pest, clover root weevil: The key to its own demise? [Mitogenome announcement]. Mitochondrial DNA Part B, 4(1), 878-879. doi: 10.1080/23802359.2018.1561218
Conference Contribution - Published proceedings: Abstract
Inwood, S. N., Harrop, T. W., & Dearden, P. K. (2019). Dual-species transcriptomics to investigate parasitism resistance in a classic biological control system. Proceedings of the 16th Asian Conference on Transcription. (pp. 71). Retrieved from https://act2019.p.events4you.currinda.com/days/2019-12-02
Dearden, P. K. (2019). Genomics and the transformation of biology [Plenary]. Proceedings of the Genome Alliance in Australasia (GAiA) Symposium. (pp. 1). Retrieved from https://web.cvent.com/event/ac7f6278-c62b-4c89-86cc-b1e57af267df/websitePage:650682dc-8168-4fcc-9431-93e8f5b5f828
Dearden, P., Duncan, E. J., Gimenez, G., Gruber, M. A. M., Guhlin, J., Harrop, T. W. R., … McLaughlin, G., Permina, E., … Remnant, E. J., Stockwell, P., Quinn, O., & Wilson-Rankin, E. E. (2019). The genomes of three invasive social wasps. Proceedings of the Genetics Society of Australasia (GSA) Conference. Retrieved from https://event.crowdcompass.com/gsa2019
McCulloch, G. A., Foster, B. J., Dearden, P. K., & Waters, J. M. (2019). Rapid genomic and transcriptomic shifts underpin parallel ecological speciation in alpine insects. Proceedings of the Genetics Society of Australasia (GSA) Conference. Retrieved from https://event.crowdcompass.com/gsa2019
Guhlin, J., Foster, Y., Le Lec, M., Digby, A., Urban, L., Davis, T., & Dearden, P. (2019). Large birds, small population: Genomics of the endangered Kākāpō. Proceedings of the Genetics Society of Australasia (GSA) Conference. Retrieved from https://event.crowdcompass.com/gsa2019
Dearden, P., Duncan, E. J., Gimenez, G., Gruber, M. A. M., Guhlin, J., Harrop, T. W. R., … McLaughlin, G., Permina, E., … Stockwell, P., Quinn, O., & Wilson-Rankin, E. E. (2019). High-quality Schistosoma haematobium genome achieved by single-molecule and long-range sequencing. Proceedings of the Genetics Society of Australasia (GSA) Conference. Retrieved from https://event.crowdcompass.com/gsa2019
Conference Contribution - Verbal presentation and other Conference outputs
Graves, J., & Dearden, P. (2019, July). Engagement with public, government and industry. Verbal presentation at the Genome Alliance in Australasia (GAiA) Symposium, Melbourne, Australia.
Dearden, P. (2019, July). Ethical, legal, social implications and indigenous rights. Verbal presentation at the Genome Alliance in Australasia (GAiA) Symposium, Melbourne, Australia.
Working Paper; Discussion Paper; Technical Report
Penman, D., Scott, B., Allison, J., Buckley, T., Dearden, P., Drummond, A., … Henaghan, M., … Matisoo-Smith, L., … Robertson, S., Wilcox, P., Everett-Hincks, J., King, M., … Fineran, P., Gemmell, N., … Scott, M. (2019). Gene editing: Scenarios in pest control. Wellington, New Zealand: Royal Society Te Apārangi. [Technical/Scientific Report].
Penman, D., Scott, B., Allison, J., Buckley, T., Dearden, P., Drummond, A., … Henaghan, M., … Matisoo-Smith, L., … Robertson, S., Wilcox, P., Everett-Hincks, J., McMillan, J., & Snelling, J. (2019). Gene editing: Scenarios in healthcare. (pp. 1-27). Wellington, New Zealand: Royal Society Te Apārangi. [Technical/Scientific Report].
2018
Journal - Research Article
Veale, A. J., Foster, B. J., Dearden, P. K., & Waters, J. M. (2018). Genotyping-by-sequencing supports a genetic basis for wing reduction in an alpine New Zealand stonefly. Scientific Reports, 8, 16275. doi: 10.1038/s41598-018-34123-1
Pushparajan, C., Goswami, S. K., McAdam, C. J., Hanton, L. R., Dearden, P. K., Moratti, S. C., & Cridge, A. G. (2018). A mechanically strengthened polyacrylamide gel matrix fully compatible with electrophoresis of proteins and nucleic acids. Electrophoresis, 39(5-6), 824-832. doi: 10.1002/elps.201700303
Journal - Research Other
Dearden, P. K., Gemmell, N. J., Mercier, O. R., Lester, P. J., Scott, M. J., Newcomb, R. D., … Penman, D. R. (2018). The potential for the use of gene drives for pest control in New Zealand: A perspective. Journal of the Royal Society of New Zealand, 48(4), 225-244. doi: 10.1080/03036758.2017.1385030
Conference Contribution - Published proceedings: Abstract
Cridge, A. G., Harrop, T. W. R., & Dearden, P. K. (2018). CYP450 gene expression and polymorphisms in Honey Bees as a biomarkers for exposure to environmental insecticides. Proceedings of the New Zealand Microbiological Society (NZMS) New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) Joint Annual Conference: Microbes & Molecules. (pp. 87-88). Retrieved from https://www.nzmsconference.org.nz
Waters, J., Dearden, P., Foster, B., McCulloch, G., & Hay, E. (2018). The evolution of flightless insects: Natural selection underpins parallel clinal wing reduction in alpine stoneflies. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the 6th Asia-Pacific Chromosome Colloquium. GSA2018_APCC682126. Retrieved from https://gsa2018.dryfta.com/en
Al-Jiab, R., Gemmell, N., Dearden, P., & Tompkins, D. (2018). The "Trojan Female Technique": A novel pest control method, combined with CRISPR/Cas9 to tackle current control limitations. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the 6th Asia-Pacific Chromosome Colloquium. GSA2018_APCC61025. Retrieved from https://gsa2018.dryfta.com/en
Sripaoraya, E., Longnecker, N., Dearden, P., & Griffin, I. (2018). Effectiveness of NSM Science Caravan as a science outreach for rural communities in Thailand. Proceedings of the 15th International Public Communication of Science and Technology (PCST) Conference. (pp. 394). Retrieved from https://pcst.co/conferences
Pushparajan, C., Cridge, A., & Dearden, P. (2018). Targeting the Torso signalling pathway to identify bee-friendly insecticides. New Biotechnology, 44(Suppl.), (pp. S58). doi: 10.1016/j.nbt.2018.05.053
Conference Contribution - Verbal presentation and other Conference outputs
Dearden, P. K. (2018, August). Genomics Aotearoa: Aiming to improve the use of genomics in New Zealand. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Cridge, A., Armstrong, K. F., Harrop, T. W. R., & Dearden, P. K. (2018, November). Using environmental DNA to identify and monitor new plant incursions into New Zealand. Verbal presentation at the MapNet meeting, Dunedin, New Zealand.
Lamichhane, R., de la Harpe, S., Harrop, T., Vernall, A., Tyndall, J., Dearden, P., Kirman, J., & Ussher, J. E. (2018, August). Differential regulation of MR1- and cytokine stimulated MAIT cells. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.
Other Research Output
Dearden, P. (2018, May). Genetic, genomic, and epigenetic architecture of a plastic trait. Department of Biochemistry, University of Otago, Dunedin, New Zealand. [Department Seminar].
2017
Chapter in Book - Research
Cridge, A., Harrop, T., Lovegrove, M., Remnant, E., & Dearden, P. (2017). Nutrition and epigenetic change in insects: Evidence and implications. In H. Verlinden (Ed.), Advances in insect physiology (Vol. 53): Insect epigenetics. (pp. 31-54). London, UK: Academic Press. doi: 10.1016/bs.aiip.2017.06.001
Journal - Research Article
Wu, C., Jordan, M. D., Newcomb, R. D., Gemmell, N. J., Bank, S., Meusemann, K., Dearden, P. K., … Grosser, S., … Buckley, T. R. (2017). Analysis of the genome of the New Zealand giant collembolan (Holacanthella duospinosa) sheds light on hexapod evolution. BMC Genomics, 18, 795. doi: 10.1186/s12864-017-4197-1
Cridge, A. G., Lovegrove, M. R., Skelly, J. G., Taylor, S. E., Petersen, G. E. L., Cameron, R. C., & Dearden, P. K. (2017). The honeybee as a model insect for developmental genetics. Genesis, 55(5), e23019. doi: 10.1002/dvg.23019
Conference Contribution - Published proceedings: Abstract
Veale, A., Foster, B., Dearden, P., & Waters, J. (2017). Use it or lose it? The genomic mechanisms underlying wing-loss in New Zealand's alpine stoneflies. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 550. Retrieved from http://gen2017.w.events4you.currinda.com
Lovegrove, M. R., Duncan, E. J., & Dearden, P. K. (2017). Evolving eusociality: Using Drosophila to understand how queen pheromone inhibits reproduction in worker honeybees. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 543. Retrieved from http://gen2017.w.events4you.currinda.com
Taylor, S., & Dearden, P. (2017). The terminal patterning gene Torso-like is an essential component of the vitelline membrane in the wasp Nasonia vitripennis. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 89). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html
Lester, P., Gemmell, N., Tompkins, D., Jalilzadeh, A., & Dearden, P. (2017). Using population genetics and genomics as next-generation approaches for the control of invasive insects: Social wasps as a case study. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 670. Retrieved from http://gen2017.w.events4you.currinda.com
Harrop, T. W. R., Jāuregui, R., Olaniyan, S., Taylor, S., Inwood, S., Jacobs, J., … Dearden, P. K. (2017). Genomics of a weevil pest and its parasitoid biocontrol agent. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 567. Retrieved from http://gen2017.w.events4you.currinda.com
Clare, A. J., Wicky, H. E., Dearden, P. K., Empson, R. M., & Hughes, S. M. (2017). Developmentally important transcription factor Fezf2 has a molecular and functional role in the mature brain. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 693. Retrieved from http://gen2017.w.events4you.currinda.com
Pushparajan, C., Cridge, A. G., & Dearden, P. K. (2017). A biomolecular luminscence complementation assay to identify a bee-friendly insecticide. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 544. Retrieved from http://gen2017.w.events4you.currinda.com
McAdam, C. J., Goswami, S. K., Moratti, S. C., Hanton, L. R., Cridge, A. G., Pushparajan, C., & Dearden, P. K. (2017). Toughening gels for biomedical applications. Proceedings of the Royal Australian Chemical Institute (RACI) Centenary Congress. (pp. 674). Retrieved from http://www.racicongress.com/
Cridge, A. G., Permina, E. A., & Dearden, P. K. (2017). Regulation and evolution of complex developmental gene networks. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 671. Retrieved from http://gen2017.w.events4you.currinda.com/
Cridge, A., Inwood, S., Sopow, S., Pawson, S., & Dearden, P. (2017). Evaluation of RNAi as a control method for giant willow aphid Tuberolachnus salignus. Proceedings of the Entomological Society of New Zealand (ESNZ) Conference. (pp. 82). Retrieved from http://ento.org.nz/conferences/
Conference Contribution - Poster Presentation (not in published proceedings)
Lamichhane, R., de la Harpe, S., Harrop, T., Vernall, A., Tyndall, J., Dearden, P., Kirman, J., & Ussher, J. (2017, November). Differences in the effector function of MR1- and cytokine stimulated MAIT cells. Poster session presented at the 10th International CD1-MR1 Workshop, Napa, USA.
Pushparajan, C., Cridge, A. G., & Dearden, P. K. (2017, September). Development of a bimolecular luminescence complementation assay to screen for inhibitors of torso signalling: In search of a bee-friendly insecticide. Poster session presented at the 25th European Drosophila Research Conference, London, UK.
Cridge, A. G., Permina, E. A., & Dearden, P. (2017, September). Evolution of complex developmental gene networks. Poster session presented at the 25th European Drosophila Research Conference, London, UK.
Conference Contribution - Verbal presentation and other Conference outputs
Duncan, E., Leask, M., & Dearden, P. K. (2017, September). Developmental plasticity and its impacts on the genome. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Working Paper; Discussion Paper; Technical Report
Panfilio, K. A., Vargas Jentzsch, I. M., Benoit, J. B., Erezyilmaz, D., Suzuki, Y., Colella, S., … Cridge, A. G., … Dearden, P. K., … Leask, M., … Lovegrove, M. R., … Richards, S. (2017). Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome. bioRxiv. doi: 10.1101/201731
2016
Journal - Research Article
Duncan, E. J., Hyink, O., & Dearden, P. K. (2016). Notch signalling mediates reproductive constraint in the adult worker honeybee. Nature Communications, 7, 12427. doi: 10.1038/ncomms12427
Cridge, A. G., Dearden, P. K., & Brownfield, L. R. (2016). Convergent occurrence of the developmental hourglass in plant and animal embryogenesis? Annals of Botany, 117(5), 833-843. doi: 10.1093/aob/mcw024
Smith, L. M., Parr-Brownlie, L. C., Duncan, E. J., Black, M. A., Gemmell, N. J., Dearden, P. K., & Reynolds, J. N. J. (2016). Striatal mRNA expression patterns underlying peak dose L-DOPA-induced dyskinesia in the 6-OHDA hemiparkinsonian rat. Neuroscience, 324, 238-251. doi: 10.1016/j.neuroscience.2016.03.012
Pires, C. V., de Paula Freitas, F. C., Cristino, A. S., Dearden, P. K., & Simões, Z. L. P. (2016). Transcriptome analysis of honeybee (Apis mellifera) haploid and diploid embryos reveals early zygotic transcription during cleavage. PLoS ONE, 11(1), e0146447. doi: 10.1371/journal.pone.0146447
Conference Contribution - Published proceedings: Abstract
Collins, K., & Dearden, P. (2016). Taking science to the people: Pop Up Science and Lab-in-a-Box. Proceedings of the Science Communicators Association of New Zealand (SCANZ) Conference. (pp. 22). Retrieved from https://www.scanz.co.nz/conference
Blommaert, J., Duncan, E., & Dearden, P. (2016). Anterior-posterior patterning in the Rotifer, Brachionus plicatilis. Proceedings of the European Society for Evolutionary Developmental Biology (EED) 6th Meeting. (pp. 336). Retrieved from http://evodevo.eu/
Lovegrove, M. R., Duncan, E. J., & Dearden, P. K. (2016). Evolving eusociality: Using drosophila to understand how queen pheromone inhibits reproduction in worker honeybees. Proceedings of the European Society for Evolutionary Developmental Biology (EED) 6th Meeting. (pp. 307-308). Retrieved from http://evodevo.eu/
Cridge, A. G., Permina, E., & Dearden, P. K. (2016). Evolution of early acting events in development: Regulation and evolution of complex gene networks. Proceedings of the European Society for Evolutionary Developmental Biology (EED) 6th Meeting. (pp. 207-208). Retrieved from http://evodevo.eu/
Dearden, P. K., Duncan, E., Tidswell, O., & Beck, C. (2016). Linking Noggin and terminal patterning. Proceedings of the European Society for Evolutionary Developmental Biology (EED) 6th Meeting. (pp. 100). Retrieved from http://evodevo.eu/
2015
Journal - Research Article
Ellisdon, A. M., Reboul, C. F., Panjikar, S., Huynh, K., Oelling, C. A., Winter, K. L., … Dearden, P. K., … McGowan, S. (2015). Stonefish toxin defines an ancient branch of the perforin-like superfamily. PNAS, 112(50), 15360-15365. doi: 10.1073/pnas.1507622112
Sharpe, M. L., Dearden, P. K., Gimenez, G., & Krause, K. L. (2015). Comparative RNA seq analysis of the New Zealand glowworm Arachnocampa luminosa reveals bioluminescence-related genes. BMC Genomics, 16, 825. doi: 10.1186/s12864-015-2006-2
Paten, A. M., Duncan, E. J., Pain, S. J., Peterson, S. W., Kenyon, P. R., Blair, H. T., & Dearden, P. K. (2015). Functional development of the adult ovine mammary gland: Insights from gene expression profiling. BMC Genomics, 16, 748. doi: 10.1186/s12864-015-1947-9
Dearden, P. K. (2015). Origin and evolution of the enhancer of split complex. BMC Genomics, 16, 712. doi: 10.1186/s12864-015-1926-1
Sadd, B. M., Barribeau, S. M., Bloch, G., de Graaf, D. C., Dearden, P., Elsik, C. G., … Cridge, A. G., … Duncan, E., … Irvine, F., … Leask, M., Lockett, G. A., … Nair, A., … Blommaert, J., … Worley, K. C. (2015). The genomes of two key bumblebee species with primitive eusocial organization. Genome Biology, 16, 76. doi: 10.1186/s13059-015-0623-3
Cridge, A. G., Leask, M. P., Duncan, E. J., & Dearden, P. K. (2015). What do studies of insect polyphenisms tell us about nutritionally-triggered epigenomic changes and their consequences? Nutrients, 7(3), 1787-1797. doi: 10.3390/nu7031787
Conference Contribution - Verbal presentation and other Conference outputs
Dearden, P. (2015, November). Searching for novel targets for insecticides. Verbal presentation at the Toxicology Symposium: Toxicology for the Modern Researcher, Dunedin, New Zealand.
2014
Chapter in Book - Research
Osborne, A. J., Duncan, E. J., Cridge, A. G., & Dearden, P. K. (2014). Epigenetics and the maternal germline. In T. Tollefsbol (Ed.), Transgenerational epigenetics: Evidence and debate. (pp. 27-41). London, UK: Academic Press. doi: 10.1016/B978-0-12-405944-3.00004-0
Journal - Research Article
Kenny, N. J., Namigai, E. K. O., Dearden, P. K., Hui, J. H. L., Grande, C., & Shimeld, S. M. (2014). The lophotrochozoan TGF-β signalling cassette: Diversification and conservation in a key signalling pathway. International Journal of Developmental Biology, 58, 533-549. doi: 10.1387/ijdb.140080nk
Chipman, A. D., Ferrier, D. E. K., Brena, C., Qu, J., Hughes, D. S. T., Schröder, R., … Dearden, P. K., … Duncan, E. J., … Kenny, N. J., … Richards, S. (2014). The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima. PLoS Biology, 12(11), e1002005. doi: 10.1371/journal.pbio.1002005
Dearden, P. K. (2014). Expression pattern of empty-spiracles, a conserved head-patterning gene, in honeybee (Apis mellifera) embryos. Gene Expression Patterns, 15(2), 142-148. doi: 10.1016/j.gep.2014.06.003
Paten, A. M., Paine, S.-J., Peterson, S. W., Blair, H. T., Kenyon, P. R., Dearden, P. K., & Duncan, E. J. (2014). Identification of reference genes for RT-qPCR in ovine mammary tissue during late-pregnancy, lactation and in response to maternal nutritional programming. Physiological Genomics, 46, 560-570. doi: 10.1152/physiolgenomics.00030.2014
Wilson, M. J., Kenny, N. J., & Dearden, P. K. (2014). Components of the dorsal-ventral pathway also contribute to anterior-posterior patterning in honeybee embryos (Apis mellifera). EvoDevo, 5, 11. doi: 10.1186/2041-9139-5-11
Duncan, E. J., Gluckman, P. D., & Dearden, P. K. (2014). Epigenetics, plasticity, and evolution: How do we link epigenetic change to phenotype? Journal of Experimental Zoology Part B: Molecular & Developmental Evolution, 322(4), 208-220. doi: 10.1002/jez.b.22571
Journal - Research Other
Macaulay, E. C., Donovan, E. L., Leask, M. P., Bloomfield, F. H., Vickers, M. H., Dearden, P. K., … and on behalf of the Gravida International College Summit Team. (2014). The importance of early life in childhood obesity and related diseases: A report from the 2014 Gravida Strategic Summit. Journal of Developmental Origins of Health & Disease, 5(6), 398-407. doi: 10.1017/S2040174414000488
Duncan, E. J., Johnson, T. K., Whisstock, J. C., Warr, C. G., & Dearden, P. K. (2014). Capturing embryonic development from metamorphosis: How did the terminal patterning signalling pathway of Drosophila evolve? Current Opinion in Insect Science, 1, 45-51. doi: 10.1016/j.cois.2014.04.007
Conference Contribution - Published proceedings: Abstract
Sharpe, M., Dearden, P., Gimenez, G., & Krause, K. (2014). Transcriptome of the New Zealand glowworm, Arachnocampa luminosa. Luminescence, 29(Suppl. 1), (pp. 45-46). doi: 10.1002/bio.2699_2
Cridge, A. G., & Dearden, P. K. (2014). Constraining and buffering: Regulation and evolution of complex gene networks. Proceedings of the 35th Annual Lorne Genome Conference. Retrieved from http://genome-2014.m.asnevents.com.au/
Duncan, E., O'Neill, M., & Dearden, P. (2014). DNA methylation and phenotypic plasticity: Is DNA methylation a conserved mechanism for phenotypic plasticity in insects? Proceedings of the 5th European Society for Evolutionary Developmental Biology Meeting. (pp. 259-260). Retrieved from http://evodevo2014.univie.ac.at/
Duncan, E., & Dearden, P. (2014). A mechanism for reproductive constraint in the honeybee. Proceedings of the 5th European Society for Evolutionary Developmental Biology Meeting. (pp. 192). Retrieved from http://evodevo2014.univie.ac.at/
Dearden, P., Leask, M., & Duncan, E. (2014). Phenotypic plasticity and epigenetics in the honeybee ovary. Proceedings of the 5th European Society for Evolutionary Developmental Biology Meeting. (pp. 120-121). Retrieved from http://evodevo2014.univie.ac.at/
Cridge, A., & Dearden, P. (2014). Constraining and buffering: Regulation and evolution of complex gene networks. Proceedings of the 5th European Society for Evolutionary Developmental Biology Meeting. (pp. 150). Retrieved from http://evodevo2014.univie.ac.at/
2013
Journal - Research Article
Cameron, R. C., Duncan, E. J., & Dearden, P. K. (2013). Biased gene expression in early honeybee larval development. BMC Genomics, 14, 903. doi: 10.1186/1471-2164-14-903
Cameron, R. C., Duncan, E. J., & Dearden, P. K. (2013). Stable reference genes for the measurement of transcript abundance during larval caste development in the honeybee. Apidologie, 44(4), 357-366. doi: 10.1007/s13592-012-0187-0
Hyink, O., Laas, F., & Dearden, P. K. (2013). Genetic tests for alleles of complementary-sex-determiner to support honeybee breeding programmes. Apidologie, 44(3), 306-313. doi: 10.1007/s13592-012-0181-6
Kenny, N. J., & Dearden, P. K. (2013). NMDA receptor expression and C terminus structure in the rotifer Brachionus plicatilis and long-term potentiation across the Metazoa. Invertebrate Neuroscience, 13, 125-134. doi: 10.1007/s10158-013-0154-0
Duncan, E. J., Benton, M. A., & Dearden, P. K. (2013). Canonical terminal patterning is an evolutionary novelty. Developmental Biology, 377, 245-261. doi: 10.1016/j.ydbio.2013.02.010
Duncan, E. J., Leask, M. P., & Dearden, P. K. (2013). The pea aphid (Acyrthosiphon pisum) genome encodes two divergent early developmental programs. Developmental Biology, 377, 262-274. doi: 10.1016/j.ydbio.2013.01.036
Wilson, M. J., & Dearden, P. K. (2013). RNA localization in the honeybee (Apis mellifera) oocyte reveals insights about the evolution of RNA localization mechanisms. Developmental Biology, 375(2), 193-201. doi: 10.1016/j.ydbio.2013.01.001
Conference Contribution - Published proceedings: Abstract
Osborne, A., Morgan, S., Ramsey, P., & Dearden, P. (2013). Transgenerational inheritance of response to nutritional challenge, and the genetic mechanisms underlying predictive adaptive responses. Proceedings of the Gravida Annual Science Symposium: How Can We Create a Better Future For All New Zealanders? Retrieved from http://www.gravida.org.nz/video/gravida-science-symposium-2013/
Conference Contribution - Verbal presentation and other Conference outputs
Dearden, P. (2013, September). How honey bees can improve our health and save the world. Verbal presentation at the Inaugural Genetics Week, Dunedin, New Zealand.
Dearden, P. (2013, September). Living longer through cake. Verbal presentation at the Inaugural Genetics Week, Dunedin, New Zealand.
Duncan, E. J., & Dearden, P. K. (2013, August). Epigenetics and the environment: Are changes in DNA methylation associated with phenotypic plasticity? Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2012
Journal - Research Article
Zondag, L., Dearden, P. K., & Wilson, M. J. (2012). Deep sequencing and expression of microRNAs from early honeybee (Apis mellifera) embryos reveals a role in regulating early embryonic patterning. BMC Evolutionary Biology, 12, 211. doi: 10.1186/1471-2148-12-211
Wilson, M. J., & Dearden, P. K. (2012). Pair-rule gene orthologues have unexpected maternal roles in the honeybee (Apis mellifera). PLoS ONE, 7(9), e46490. doi: 10.1371/journal.pone.0046490
Chua, J. P. S., Wallace, E. J. S., Yardley, J. A., Duncan, E. J., Dearden, P. K., & Summerfield, T. C. (2012). Gene expression indicates a zone of heterocyst differentiation within the thallus of the cyanolichen Pseudocyphellaria crocata. New Phytologist, 196(3), 862-872. doi: 10.1111/j.1469-8137.2012.04272.x
Conference Contribution - Published proceedings: Abstract
Morgan, S., Raubenheimer, D., & Dearden, P. K. (2012). How to live longer by investing in yourself. Proceedings of the Centre for Reproduction and Genomics 4th Annual Research Colloquium. (pp. 12). Retrieved from http://www.otago.ac.nz/crg/news/colloquium/
Smith, L. M., Duncan, E. J., Parr-Brownlie, L. C., Black, M. A., Dearden, P. K., & Reynolds, J. N. J. (2012). Transcriptome analysis of levodopa-induced dyskinesias in the 6-hydroxydopamine hemiparkinsonian rat. Proceedings of the Society for Neuroscience 42nd Annual Meeting. SfN. Retrieved from http://www.sfn.org/index.aspx?pagename=abstracts_am2012
Smith, L., Duncan, E., Parr-Brownlie, L., Black, M., Dearden, P., & Reynolds, J. (2012). Understanding the mechanisms behind levodopa-induced dyskinesias. New Zealand Medical Journal, 125(1364). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Verbal presentation and other Conference outputs
Morgan, S. M., Raubenheimer, D., & Dearden, P. K. (2012, November). Nutrition forced extension of lifespan in Drosophila: A whole-genome investigation. Verbal presentation at the Gravida Annual Science Symposium: What Makes the Best Start for a Healthy Life? Palmerston North, New Zealand.
Duncan, E. J., O'Neill, M., Leask, M. P., & Dearden, P. K. (2012, November). Phenotypic plasticity in the pea aphid: Do the same molecular mechanisms underpin plasticity in different species? Verbal presentation at the Gravida Annual Science Symposium: What Makes the Best Start for a Healthy Life? Palmerston North, New Zealand.
Nair, A., & Dearden, P. K. (2012, November). Genetic assimilation: Revisiting the 60-year-old evolutionary paradox. Verbal presentation at the Gravida Annual Science Symposium: What Makes the Best Start for a Healthy Life? Palmerston North, New Zealand.
Leask, M. P., Duncan, E. J., & Dearden, P. K. (2012, November). Epigenetics in the honeybee ovary. Verbal presentation at the Gravida Annual Science Symposium: What Makes the Best Start for a Healthy Life? Palmerston North, New Zealand.
Dearden, P. K. (2012, August). Plasticity and reproductive constraint in the honeybee. Invited presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2011
Journal - Research Article
Wilson, M. J., & Dearden, P. K. (2011). Diversity in insect axis formation: Two orthodenticle genes and hunchback act in anterior patterning and influence dorsoventral organization in the honeybee (Apis mellifera). Development, 138(16), 3497-3507. doi: 10.1242/dev.067926
Wilson, M. J., Abbott, H., & Dearden, P. K. (2011). The evolution of oocyte patterning in insects: Multiple cell-signaling pathways are active during honeybee oogenesis and are likely to play a role in axis patterning. Evolution & Development, 13(2), 127-137. doi: 10.1111/j.1525-142X.2011.00463.x
Conference Contribution - Verbal presentation and other Conference outputs
Duncan, E., & Dearden, P. K. (2011, September). The evolution of a chromatin domain. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Morgan, S. M., Raubenheimer, D., & Dearden, P. K. (2011, September). The genetics of dietary restriction forced lifespan extension. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
McCartney, R. C., & Dearden, P. K. (2011, September). Hexamerins are key regulators of caste development in the honeybee. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Wilson, M. J., & Dearden, P. K. (2011, September). Laying down the material blueprint: The role of RNA localization in the evolution of body patterning. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Duncan, E. J., Romeril, A. J., & Dearden, P. K. (2011, September). Notch signalling and ovary activation in the honeybee: A new role for an old pathway? Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2010
Chapter in Book - Research
Dearden, P. K., Duncan, E. J., & Wilson, M. J. (2010). The honeybee Apis mellifera. In Emerging model organisms: A laboratory manual (Vol. 2). (pp. 223-246). Cold Spring Harbor, NY: Cold Spring Harbor Press.
Journal - Research Article
Wilson, M. J., McKelvey, B. H., van der Heide, S., & Dearden, P. K. (2010). Notch signaling does not regulate segmentation in the honeybee, Apis mellifera. Development Genes & Evolution, 220(7-8), 179-190. doi: 10.1111/j.1365-2826.2010.02100.x
Smith, J. M., Cridge, A. G., & Dearden, P. K. (2010). Germ cell specification and ovary structure in the rotifer Brachionus plicatilis. EvoDevo, 1, 5. doi: 10.1186/2041-9139-1-5
The International Aphid Genomics Consortium, including Smith, J., Wilson, M., Dearden, P., & Duncan, E. J. (2010). Genome sequence of the pea aphid Acyrthosiphon pisum. PLoS Biology, 8(2), e1000313. doi: 10.1371/journal.pbio.1000313
Duncan, E. J., & Dearden, P. K. (2010). Evolution of a genomic regulatory domain: The role of gene co-option and gene duplication in the enhancer of split complex. Genome Research, 20, 917-928. doi: 10.1101/gr.104794.109
Shigenobu, S., Bickel, R. D., Brisson, J. A., Butts, T., Chang, C.-C., Christiaens, O., … Duncan, E. J., … Smith, J., … Wilson, M. J., Dearden, P. K., & Stern, D. L. (2010). Comprehensive survey of developmental genes in the pea aphid, Acyrthosiphon pisum: Frequent lineage-specific duplications and losses of developmental genes. Insect Molecular Biology, 19(Suppl. 2), 47-62. doi: 10.1111/j.1365-2583.2009.00944.x
Wilson, M. J., Havler, M., & Dearden, P. K. (2010). Giant, Krüppel, and caudal act as gap genes with extensive roles in patterning the honeybee embryo. Developmental Biology, 339(1), 200-211. doi: 10.1016/j.ydbio.2009.12.015
Other Research Output
Dearden, P. (2010, October). Living longer through cake. Genetics Otago Southern Science Series. Wanaka, New Zealand. [Public Seminar].
2009
Journal - Research Article
Wilson, M. J., & Dearden, P. K. (2009). Tailless patterning functions are conserved in the honeybee even in the absence of Torso signaling. Developmental Biology, 335(1), 276-287. doi: 10.1016/j.ydbio.2009.09.002
Dearden, P. K., Duncan, E. J., & Wilson, M. J. (2009). Fixation and storage of honeybee (Apis mellifera) tissues. Cold Spring Harbor Protocols, 4(6). doi: 10.1101/pdb.prot5224
Dearden, P. K., Duncan, E. J., & Wilson, M. J. (2009). Rna interference (RNAi) in honeybee (Apis mellifera) embryos. Cold Spring Harbor Protocols, 4(6). doi: 10.1101/pdb.prot5228
Dearden, P. K., Duncan, E. J., & Wilson, M. J. (2009). In situ hybridization of sectioned honeybee (Apis mellifera) tissues. Cold Spring Harbor Protocols, 4(6). doi: 10.1101/pdb.prot5226
Dearden, P. K., Duncan, E. J., & Wilson, M. J. (2009). Whole-mount in situ hybridization of honeybee (Apis mellifera) tissues. Cold Spring Harbor Protocols, 4(6). doi: 10.1101/pdb.prot5225
Dearden, P. K., Duncan, E. J., & Wilson, M. J. (2009). Immunohistochemistry on honeybee (Apis mellifera) embryos. Cold Spring Harbor Protocols, 4(6). doi: 10.1101/pdb.prot5227
Dearden, P. K., Duncan, E. J., & Wilson, M. J. (2009). The honeybee Apis mellifera. Cold Spring Harbor Protocols, 4(6). doi: 10.1101/pdb.emo123
Specht, D., Wu, S.-b., Turner, P., Dearden, P., Koentgen, F., Wolfrum, U., Maw, M., … tom Dieck, S. (2009). Effects of presynaptic mutations on a postsynaptic Cacna1s calcium channel colocalized with mGluR6 at mouse photoreceptor ribbon synapses. Investigative Ophthalmology & Visual Science, 50(2), 505-515. doi: 10.1167/iovs.08-2758
Conference Contribution - Published proceedings: Abstract
Duncan, E. J., & Dearden, P. K. (2009). Race you to the end: Terminal patterning, a fast evolving developmental pathway in insects. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Smith, J. M., & Dearden, P. K. (2009). Evo-Devo's Next Top Model: Transcriptome analysis of the rotifer Brachionus plicatilis, a new model system for the Lophotrochozoa. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
McCartney, R. C., & Dearden, P. K. (2009). The honey bee polyphenism. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Morgan, S. M., Raubenheimer, D., & Dearden, P. K. (2009). Molecular correlates of life history trade-offs. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Morgan, S., Dearden, P., & Raubenheimer, D. (2009). Molecular correlates of life history trade-offs. Mechanisms of Development. 126(Supplement 1), (pp. S332-S333). [Abstract]
2008
Journal - Research Article
Wilson, M. J., & Dearden, P. K. (2008). Evolution of the insect Sox genes. BMC Evolutionary Biology, 8, 120. doi: 10.1186/1471-2148-8-120
Duncan, E. J., Wilson, M. J., Smith, J. M., & Dearden, P. K. (2008). Evolutionary origin and genomic organisation of runt-domain containing genes in arthropods. BMC Genomics, 9, 588. doi: 10.1186/1471-2164-9-558
Young, J. M., Juengel, J. L., Dodds, K. G., Laird, M., Dearden, P. K., McNeilly, A. S., … Wilson, T. (2008). The activin receptor-like kinase 6 Booroola mutation enhances suppressive effects of bone morphogenetic protein 2 (BMP2), BMP4, BMP6 and growth and differentiation factor-9 on FSH release from ovine primary pituitary cell cultures. Journal of Endocrinology, 196(2), 251-261. doi: 10.1677/JOE-07-0148
Conference Contribution - Published proceedings: Abstract
McCartney, R. C., & Dearden, P. K. (2008). The honeybee polyphenism. Proceedings of the 8th Annual Australasian Microarray and Associated Technologies (AMATA) Conference. Retrieved from http://www.amata.org.au/index.php/resources/2008-conference-abstracts
Morgan, S. M., Dearden, P. K., & Raubeheimer, D. (2008). Molecular correlates of life history tradeoffs. Proceedings of the 8th Annual Australasian Microarray and Associated Technologies (AMATA) Conference. Retrieved from http://www.amata.org.au/index.php/resources/2008-conference-abstracts
Dearden, P. K. (2008). Probing the architecture of developmental plasticity. Proceedings of the 8th Annual Australasian Microarray and Associated Technologies (AMATA) Conference. Retrieved from http://www.amata.org.au/index.php/resources/2008-conference-abstracts
2006
Journal - Research Article
Sabater-Muñoz, B., Legeai, F., Rispe, C., Bonhomme, J., Dearden, P., Dossat, C., … Tagu, D. (2006). Large-scale gene discovery in the pea aphid Acyrthosiphon pisum (Hemiptera). Genome Biology, 7(R21). doi: 10.1186/gb-2006-7-3-r21
The Honeybee Genome Sequencing Consortium, including Beggs, K. T., Mercer, A. R., Dearden, P. K., & Wilson, M. J. (2006). Insights into social insects from the genome of the honeybee Apis mellifera. Nature, 443, 931-949.
Dearden, P. K., Wilson, M. J., Sablan, L., Osborne, P. W., Havler, M., McNaughton, E., … Beye, M. (2006). Patterns of conservation and change in honey bee developmental genes. Genome Research, 16(11), 1376-1384. doi: 10.1101/gr.5108606
Dearden, P. K. (2006). Germ cell development in the Honeybee (Apis mellifera); Vasa and Nanos expression. BMC Developmental Biology, 6, 6. doi: 10.1186/1471-213X-6-6
2005
Journal - Research Article
Hemara-Wahanui, A., Berjukow, S., Hope, C. I., Dearden, P. K., Wu, S.-B., Wilson-Wheeler, J., … Maw, M. A. (2005). A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of CaV1.4 channel activation. PNAS, 102(21), 7553-7558.
Osborne, P. W., & Dearden, P. K. (2005). Expression of Pax group III genes in the honeybee (Apis mellifera). Development Genes & Evolution, 215(10), 499-508. doi: 10.1007/s00427-005-0008-9
Osborne, P., & Dearden, P. K. (2005). Non-radioactive in-situ hybridisation to honeybee embryos and ovaries. Apidologie, 36, 113-118.
Conference Contribution - Published proceedings: Abstract
Dearden, P. K., & Cridge, A. (2005). Expression and function of Pax genes in the rotifer Brachionus plicatilis. Mechanisms of Development. 122(Suppl. 1), (pp. S162). [Abstract]
Wilson, M. J., & Dearden, P. K. (2005). Segmentation in the Honeybee (Apis Mellifera). Mechanisms of Development. 122, (pp. S154-S155). [Abstract]
2003
Journal - Research Article
Dearden, P., Grbic, M., & Donly, C. (2003). Vasa expression and germ-cell specification in the spider mite Tetranychus urticae. Development Genes & Evolution, 212, 599-603.
2002
Journal - Research Article
Dearden, P., Donly, C., & Grbic, M. (2002). Expression of pair-rule gene homologues in a chelicerate: Early patterning of the two-spotted spider mite Tetranychus urticae. Development, 129, 5461-5472.
Chang, C.-C., Dearden, P., & Akam, M. (2002). Germ line development in the grasshopper Schistocerca gregaria: vasa as a marker. Developmental Biology, 252, 100-118.
Conference Contribution - Published proceedings: Abstract
Dearden, P., Donly, C., & Grbic, M. (2002). Evolution of developmental mechanisms in the chelicerata: Genomic of spider mite Tetranychus urticae. In S. Carroll (Ed.), Developmental Biology. 247(2), (pp. 448). San Diego: Academic Press. [Abstract]
Grbic, M., Terzin, T., Zhurov, V., & Dearden, P. (2002). Evolution of developmental novelty: The proliferative phase of polyembryonic development. In S. Carroll (Ed.), Developmental Biology. 247(2), (pp. 443-444). San Diego: Academic Press. [Abstract]
2001
Journal - Research Article
Lawrence, N., Dearden, P., Hartley, D., Roose, J., Clevers, H., & Martinez-Arias, A. A. (2001). Groucho protein that lacks the WD40 repeats modulates Wingless signalling during the development and patterning of the wing in Drosophila. International Journal of Developmental Biology, 44(7), 749-756.
Dearden, P., & Akam, M. (2001). Early embryo patterning in the grasshopper, Schistocerca gregaria; wingless, dpp and caudal expression. Development, 128(18), 3435-3444.
2000
Journal - Research Article
Dearden, P., Falciani, F., & Akam, M. (2000). Maternal and early Zygotic expression of the Hox3/zen gene of the grasshopper Schistocerca gregaria. Evolution & Development, 2(5), 261-270.
Dearden, P., & Akam, M. (2000). Segmentation in silico. Nature, 406(6792), 131-132.
Dearden, P., & Akam, M. (2000). A role for Fringe in segment morphogenesis but not segment formation in the grasshopper, Schistocerca gregaria. Development Genes & Evolution, 210(7), 329-336.
1999
Journal - Research Article
Dearden, P., & Akam, M. (1999). Developmental evolution: Axial patterning in insects. Current Biology, 26(9), R591-R594.