Profile

Contact Details

Phone: +64 3 556 5036
Email: jerin.mathew@otago.ac.nz

University Links

Position

Lecturer in Clinical Anatomy

Department

Department of Anatomy

Qualifications

BPhty (India) PhD (Otago)

Research summary

Neural correlates of pain and non-invasive neuromodulation for chronic musculoskeletal pain

Teaching

Undergraduate:

PHTY250 (Physiotherapy 2nd year)
Early Learning in Medicine (ELM2 and ELM3)
Advanced Learning in Medicine (ALM5)
Introdution to Pain (ELM2)

Postgraduate:

Postgraduate Diploma in Surgical Anatomy (SUAN)
Basic Surgical Sciences Course (for candidates taking FRACS)
Pain and Pain Management Programmes, University of Otago, Christchurch

Memberships

International Association for the Study of Pain (IASP)
New Zealand Pain Society (NZPS)
Centre for Bioengineering and Nanomedicine (Point-of-care technologies)
International Society for Neuroregulation & Research (ISNR)
Australian and New Zealand Association of Clinical Anatomists (ANZACA)
Clinical Anatomy Research Group (CARG)
Neuroscience Research Group (NRG)
Otago Pain Mechanisms and Neuromodulation (OPaMeN)
Pain at Otago Research Theme
Brain Health Research Centre (BHRC)
Centre for Health, Activity, and Rehabilitation Research (CHARR)
Indian Association of Physiotherapists (IAP)

Clinical

Investigating neural correlates (EEG biomarkers) of pain hypersensitivity
Clinical anatomy and biomechanics of the musculoskeletal system

Research

Dr Jerin Mathew's research primarily focuses on chronic pain and non-invasive neuromodulation. With a background in physiotherapy and neuroscience, he conducts applied and clinical research to investigate the 'brain-pain' mechanisms driving chronic musculoskeletal pain and to enhance clinical pain outcomes through non-invasive neuromodulation. Dr Mathew utilises a range of techniques, including Electroencephalography, Neuroimaging, Ultrasound, Quantitative Sensory Testing, Energy Expenditure Index, and Kinematic Movement Analysis, to investigate the interaction between the musculoskeletal system and the brain.

In addition to his core research areas, Dr Mathew is involved in various collaborative research in professional clinical education, dissection/cadaveric research, brain-organ interaction, rehabilitation, and clinical sonoanatomy. He serves as a principal investigator for various interdisciplinary research programmes, including:

Additionally, he supervises postgraduate students in medicine, anatomy and neuroscience, fostering research within his areas of expertise.

Publications

Mathew, J., Adhia, D. B., Smith, M. L., De Ridder, D., & Mani, R. (2024). Closed-loop infraslow brain–computer interface can modulate cortical activity and connectivity in individuals with chronic painful knee osteoarthritis: A secondary analysis of a randomized placebo-controlled clinical trial. Clinical EEG & Neuroscience. Advance online publication. doi: 10.1177/15500594241264892 Journal - Research Article

O'Sullivan, P., Harris, I., Emerson, A., Mathew, J., Ashton-James, C., & Belton, J. (2024, March). Empowering MSK pain management. Panel discussion at the New Zealand Pain Society (NZPS) Annual Scientific Meeting: Empowering Pain Management in New Zealand, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs

Mathew, J. (2024). Neurofeedback: An emerging and experimental top-down approach for pain management [Invited]. Proceedings of the New Zealand Pain Society (NZPS) Annual Scientific Meeting: Empowering Pain Management in New Zealand. Retrieved from https://www.nzps2024.nz/ Conference Contribution - Published proceedings: Abstract

Mathew, J. (2024). Alterations in brain-pain mechanisms among individuals with chronic painful knee osteoarthritis: Insights from a neuroimaging investigation [Invited]. Proceedings of the New Zealand Pain Society (NZPS) Annual Scientific Meeting: Empowering Pain Management in New Zealand. Retrieved from https://www.nzps2024.nz/ Conference Contribution - Published proceedings: Abstract

Mani, R., Adhia, D. B., Awatere, S., Gray, A. R., Mathew, J., Wilson, L. C., Still, A., Jackson, D., Hudson, B., … De Ridder, D. (2024). Self-regulation training for people with knee osteoarthritis: A protocol for a feasibility randomised control trial (MiNT Trial). Frontiers in Pain Research, 4, 1271839. doi: 10.3389/fpain.2023.1271839 Journal - Research Other

2024

Journal - Research Article

Mathew, J., Adhia, D. B., Hall, M., De Ridder, D., & Mani, R. (2024). EEG-based cortical alterations in individuals with chronic knee pain secondary to osteoarthritis: A cross-sectional investigation. Journal of Pain, 25(5), 104429. doi: 10.1016/j.jpain.2023.11.012

Mathew, J., Perez, T. M., Adhia, D. B., De Ridder, D., & Mani, R. (2024). Is there a difference in EEG characteristics in acute, chronic, and experimentally induced musculoskeletal pain states? A systematic review. Clinical EEG & Neuroscience, 55(1), 101-120. doi: 10.1177/15500594221138292

Journal - Research Other

Conference Contribution - Published proceedings: Abstract

Conference Contribution - Verbal presentation and other Conference outputs

2023

Journal - Research Article

Rashid, M., Siby, S., Mathew, J., Basha, S. A., & Raja, K. (2023). Comparison of sway meter and Kinovea software as a tool of measurement for the sway parameters during quiet standing: An observational study. Journal of Bodywork & Movement Therapies, 35, 337-341. doi: 10.1016/j.jbmt.2023.04.082

Adhia, D. B., Mani, R., Mathew, J., O'Leary, F., Smith, M., Vanneste, S., & De Ridder, D. (2023). Exploring electroencephalographic infraslow neurofeedback treatment for chronic low back pain: A double-blinded safety and feasibility randomized placebo-controlled trial. Scientific Reports, 13, 1177. doi: 10.1038/s41598-023-28344-2

Conference Contribution - Published proceedings: Abstract

Sahota, J., Mathew, J., Khwaounjoo, P., & Cakmak, Y. O. (2023). Exploring the effect of non-invasive peroneal nerve stimulation on the autonomic nervous system at different frequencies. Proceedings of the 10th Asia Pacific International Congress of Anatomists (APICA) and the 20th Australian & New Zealand Association of Clinical Anatomists (ANZACA) Conference: Reconnect, Ka Mua, Ka Muri. Retrieved from https://apica2023.com

Conference Contribution - Verbal presentation and other Conference outputs

Mathew, J. (2023, June). Source localized EEG neurofeedback training for pain management in people with knee osteoarthritis [Flash talk]. Verbal presentation at the Te Tītoki Mataora Research Day, Auckland, New Zealand.

Brady, B., Kukutai Jones, D., Lewis, G., Davies, C., & Mathew, J. (2023, March). Equity in pain management. Panel discussion at the New Zealand Pain Society (NZPS) Annual Scientific Meeting Foundations Day, Auckland, New Zealand.

Mathew, J., & Davies, C. (2023, March). Reflections of Whānau Pain Programme: Where to next? Verbal presentation at the New Zealand Pain Society (NZPS) Annual Scientific Meeting Foundations Day, Auckland, New Zealand.

Mathew, J. (2023, March). Resting-state cortical brain activity in people with chronic painful knee osteoarthritis: A cross-sectional source localised whole-brain mapping study. Invited presentation at the New Zealand Pain Society (NZPS) Annual Scientific Meeting, Auckland, New Zealand.

2022

Journal - Research Article

Rashid, M., Harish, S. P., Mathew, J., Kalidas, A., & Raja, K. (2022). Comprehensive rehabilitation outcome measurement scale (CROMS): Development and preliminary validation of an interdisciplinary measure for rehabilitation outcomes. Health & Quality of Life Outcomes, 20, 160. doi: 10.1186/s12955-022-02048-z

Rashid, M., Siby, S., Harish, S. P., Joy, A., Gopi, A., Mathew, J., & Raja, K. (2022). Decreased postural sway in women who are visually impaired: Is it a learned protective mechanism? Journal of Visual Impairment & Blindness, 116(4), 517-525. doi: 10.1177/0145482X221120021

Mathew, J., Adhia, D. B., Smith, M. L., De Ridder, D., & Mani, R. (2022). Source localized infraslow neurofeedback training in people with chronic painful knee osteoarthritis: A randomized, double-blind, sham-controlled feasibility clinical trial. Frontiers in Neuroscience, 16, 899772. doi: 10.3389/fnins.2022.899772

Journal - Research Other

Perez, T. M., Mathew, J., Glue, P., Adhia, D. B., & De Ridder, D. (2022). Is there evidence for the specificity of closed-loop brain training in the treatment of internalizing disorders? A systematic review. Frontiers in Neuroscience, 16, 821136. doi: 10.3389/fnins.2022.821136

Conference Contribution - Published proceedings: Abstract

Mathew, J., Adhia, D., De Ridder, D., & Mani, R. (2022). Intracortical connectivity changes following infra-slow neurofeedback training in painful chronic knee osteoarthritis: A feasibility clinical trial. British Journal of Pain, 16(2, Suppl. 1), (pp. 24-25). doi: 10.1177/20494637221103093

Adhia, D. B., Mani, R., Mathew, J., O'Leary, F., Smith, M., Vanneste, S., & De Ridder, D. (2022). Electroencephalographic infraslow neurofeedback treatment for chronic low back pain: A safety and feasibility randomised placebo-controlled trial. Proceedings of the New Zealand Pain Society (NZPS) Annual Scientific Meeting. Retrieved from https://www.nzps2022.nz

Conference Contribution - Poster Presentation (not in published proceedings)

Mathew, J., Adhia, D., De Ridder, D., & Mani, R. (2022, March). EEG infraslow neurofeedback training for pain management in people with knee osteoarthritis: A randomised sham-controlled feasibility clinical trial. Poster session presented at the New Zealand Pain Society (NZPS) Annual Scientific Meeting, [Online].

Conference Contribution - Verbal presentation and other Conference outputs

Mathew, J. (2022, November). Source localised EEG neurofeedback training for pain management in people with knee osteoarthritis: A feasibility clinical trial. Verbal presentation at the Bioengineering@Otago Showcase, [Online].

Awarded Doctoral Degree

Mathew, J. (2022). Neurofeedback training for pain management in people with knee osteoarthritis (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/13704

2021

Journal - Research Article

Joy, A., Rashid, M., Baby, L., & Mathew, J. (2021). Gender differences in pain perception during experimentally induced pain: An observational study. Physiotherapy, 15(2), 89-92. doi: 10.4103/pjiap.pjiap_30_21

Rashid, M., Mathew, J., Raj, V. S., & Raja, K. (2021). Optimization of backpack loads using gait parameters in school boys. Journal of Bodywork & Movement Therapies, 25, 174-182. doi: 10.1016/j.jbmt.2020.11.014

Journal - Research Other

Perez, T. M., Glue, P., Adhia, D. B., Mathew, J., & De Ridder, D. (2021). Is there evidence for EEG-neurofeedback specificity in the treatment of internalizing disorders? A protocol for a systematic review and meta-analysis. NeuroRegulation, 8(1), 22-28. doi: 10.15540/nr.8.1.22

Conference Contribution - Published proceedings: Abstract

Perez, T., Glue, P., De Ridder, D., Adhia, D., & Mathew, J. (2021). Is there evidence for EEG-neurofeedback specificity in the treatment of internalizing disorders: A systematic review and meta-analysis. Proceedings of the International Society for Neuroregulation & Research (ISNR) 29th Annual Conference. Retrieved from https://isnr.org/

Mathew, J., Adhia, D., De Ridder, D., Smith, M. L., & Mani, R. (2021). Infra-slow EEG neurofeedback training for pain management in people with knee osteoarthritis: A pilot and feasibility clinical trial. Proceedings of the International Society for Neuroregulation & Research (ISNR) 29th Annual Conference. Retrieved from https://isnr.org/

Conference Contribution - Verbal presentation and other Conference outputs

Mathew, J. (2021, December). EEG neurofeedback training for pain management in people with knee osteoarthritis: A pilot, feasibility randomised control clinical trial. Verbal presentation at the Pain@Otago Research Symposium, [Online].

Other Research Output

Mathew, J. (2021, January). Brainwave training for osteoarthritic knee pain. Otago Tramping and Mountaineering Club, Dunedin, New Zealand. [Research Presentation].

2020

Journal - Research Article

Mathew, J., Rashid, M., Shirsath, P., & Raja, K. (2020). Development of learning material to complement pain education of physiotherapists in Indian universities: A synthesis of an action research study. OpenPhysio. doi: 10.14426/art/1126

Raja, K., Gupta, S., Mathew, J., & Rao, P. (2020). Development of training manuals for community disability workers. Physiotherapy, 14(1), 37-40. doi: 10.4103/PJIAP.PJIAP_19_19

Rashid, M., Mathew, J., & Raja, K. (2020). Alteration in ankle kinematics during uneven surface ambulation in stroke survivors: An exploratory observational study. International Journal of Health & Allied Sciences, 9(3), 262-266. doi: 10.4103/ijhas.IJHAS_20_20

Journal - Research Other

Rashid, M., Mathew, J., & Raja, K. (2020). Stance phase kinematics in ankle joint during ambulation on uneven surface: A comparison between stroke survivors and typical adults [Brief report]. Disability, CBR & Inclusive Development, 31(3), 164-178. doi: 10.47985/dcidj.379

Mathew, J., Adhia, D. B., Smith, M. L., De Ridder, D., & Mani, R. (2020). Protocol for a pilot randomized sham-controlled clinical trial evaluating the feasibility, safety, and acceptability of infraslow electroencephalography neurofeedback training on experimental and clinical pain outcomes in people with chronic painful knee. NeuroRegulation, 7(1), 30-44. doi: 10.15540/nr.7.1.30

Conference Contribution - Poster Presentation (not in published proceedings)

Mathew, J., Adhia, D., De Ridder, D., & Mani, R. (2020, November). Source-localized infra-slow EEG neurofeedback for pain management in people with knee osteoarthritis: A pilot investigation. Poster session presented at the Brain Health Research Centre Lecture and Poster Session, Dunedin, New Zealand.

Mathew, J., Adhia, D., De Ridder, D., & Mani, R. (2020, July-August). Infraslow neurofeedback for knee osteoarthritic pain: A feasibility study protocol. Poster session presented at the 28th Annual International Society for Neuroregulation and Research (ISNR) Conference, [Online].

Conference Contribution - Verbal presentation and other Conference outputs

Mathew, J., Adhia, D., De Ridder, D., & Mani, R. (2020, December). Electroencephalography neurofeedback training for pain management: Acceptability, perceived levels of effectiveness, motivation, and engagement with training in people with knee osteoarthritis. Verbal presentation at the School of Physiotherapy Postgraduate Research Symposium, Dunedin, New Zealand.

Smith, M. L., Perez, T., & Mathew, J. (2020, July-August). Infraslow neurofeedback: The latest research. Plenary presentation at the 28th Annual International Society for Neuroregulation and Research (ISNR) Conference, [Online].

2019

Journal - Research Article

Raja, K., Joseph, J. K., & Mathew, J. (2019). Students' perception of vertically integrated learning approach in physiotherapy education: An exploratory case study. Physiotherapy, 13(1), 48-51. doi: 10.4103/PJIAP.PJIAP_49_18

Conference Contribution - Verbal presentation and other Conference outputs

Mathew, J. (2019, December). Neurofeedback for knee osteoarthritic pain: A feasibility study protocol. Verbal presentation at the School of Physiotherapy Postgraduate Research Symposium: Health, Activity and Rehabilitation Research, Dunedin, New Zealand.

2018

Journal - Research Article

Raja, K., Girish, S., Gupta, S., Mathew, J., & Ganasan, V. (2018). Assessment Battery for Children with Developmental Coordination Disorder (ABCD): Preliminary report of tool development and clinical application. Journal of Pediatric Rehabilitaiton Medicine, 11(3), 175-185. doi: 10.3233/PRM-170441

Mathew, J., Raja, K., Baby, F. P., & Barikkal, B. (2018). Energy efficiency of ambulation: A comparison of various orthopaedic possibilities. Journal of Bodywork & Movement Therapies, 22(3), 622-626. doi: 10.1016/j.jbmt.2017.10.005

Raja, K., Joseph, J. K., & Mathew, J. (2018). Structured curriculum delivery in undergraduate physiotherapy education: A qualitative paper. Physiotherapy, 12(1), 30-36. doi: 10.4103/PJIAP.PJIAP_34_17

2017

Journal - Research Article

Mathew, J., Vanlalpeki, T., & Nair, G. G. (2017). Gait evaluation of institutionalized elders: A feasibility study. Indian Journal of Gerontology, 31(1), 71-83.

Raja, K., Mathew, J., & Bista, B. (2017). Generic work capacity assessment tool for working conditions in India: Preliminary results of development and standardization. International Journal of Health & Allied Sciences, 6(2), 99-112. doi: 10.4103/ijhas.IJHAS_172_16

Conference Contribution - Published proceedings: Abstract

Mathew, J., Vanlalpeki, T., & Nair, G. G. (2017). Kinematic gait variation in institutionalized elderly: implications to practice. Proceedings of the XXVI Congress of the International Society of Biomechanics and the 9th Asian-Pacific Conference on Biomechanics. P039. Retrieved from http://www.biomech2017.com/

2016

Conference Contribution - Verbal presentation and other Conference outputs

Mathew, J. (2016, April). Gait evaluation during uneven surface ambulation in stroke survivors. Verbal presentation at the Indian Federation of Neurorehabilitation (IFNR) & Neurorehabilitation Subsection of Indian Academy of Neurology Joint Conference, Bengaluru, India.