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Christine Winterbourn

Principal Investigator

MSc (Auckland), PhD (Massey) CNZM, FRSNZ

Tel 64 3 364 0564


Professor Christine Winterbourn is an Auckland University chemistry graduate who received her PhD in biochemistry from Massey University.

She did postdoctoral work at the University of British Columbia, Canada before returning to the Pathology Department, University of Otago, Christchurch, where she now has a personal chair.

Research interests

Professor Winterbourn has published more than 250 scientific papers. Her field of research is the biological chemistry of free radicals and other reactive oxidants and their involvement in health and disease.

Professor Winterbourn's focus is on understanding mechanisms of reactive oxidant production, the biochemistry of biological damage and the consequences for disease pathology.

Her current interests include:

  • the production of reactive oxidants by neutrophils and their involvement in microbial killing and inflammation
  • how neutrophils form extracellular traps (NETs)
  • how thiol proteins contribute to antioxidant defence and redox regulated cell signaling
  • biochemistry and cellular functions of mammalian peroxiredoxins
  • mechanisms of oxidative protein crosslinking
  • oxidant-antioxidant interactions in red blood cells

Other positions

  • Past member of the Health Research Council
  • Past member of the Marsden Fund Council
  • Editor of the Biochemical Journal
  • Editorial Board of Free Radical Biology and Medicine


  • University of Auckland Distinguished Alumni 2015
  • Royal Society of New Zealand's Rutherford Medal - the first woman to receive the award in its 20 year history
  • NZ Association of Scientists' Marsden Medal
  • Massey University 75th Anniversary Medal
  • Society for Free Radical Research (Australasia) Distinguished Service Award
  • University of Otago Distinguished Research Medal and Society for Free Radical Research (International) Trevor Slater Award


Ashby, L., Chan, L., Winterbourn, C., Woon, S.-T., Keating, P., Heller, R., … Chua, I., & Hsiao, K.-C. (2024). Phenotypic spectrum in a family with a novel RAC2 p.I21S dominant-activating mutation [Case report]. Clinical & Translational Immunology, 13, e1493. doi: 10.1002/cti2.1493 Journal - Research Other

Paumann-Page, M., Obinger, C., Winterbourn, C. C., & Furtmüller, P. G. (2024). Peroxidasin inhibition by phloroglucinol and other peroxidase inhibitors. Antioxidants, 13, 23. doi: 10.3390/antiox13010023 Journal - Research Article

Meotti, F., de Souza, L. F., Dempsey, B., Silva, R., Pinz, M., Cruz, L., Pace, P., Hampton, M., & Winterbourn, C. (2023). Peroxiredoxin 2 interacts with granule stress proteins in proliferative leukemic myeloid cells. Free Radical Biology & Medicine, 208(Suppl. 1), 38. doi: 10.1016/j.freeradbiomed.2023.10.053 Conference Contribution - Published proceedings: Abstract

Winterbourn, C. C., Peskin, A., Kleffmann, T., Radi, R., & Pace, P. E. (2023). Carbon dioxide/bicarbonate is required for sensitive inactivation of mammalian glyceraldehyde-3-phosphate dehydrogenase by hydrogen peroxide. PNAS, 120(18), e2221047120. doi: 10.1073/pnas.2221047120 Journal - Research Article

Magon, N. J., Turner, R., Kettle, A. J., & Winterbourn, C. C. (2023). Cross-linking between cysteine and lysine, tryptophan or tyrosine in peptides and proteins treated with hypochlorous acid and other reactive halogens. Redox Biochemistry & Chemistry. Advance online publication. doi: 10.1016/j.rbc.2023.100002 Journal - Research Article

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