Research Fellow
Email simran.maggo@otago.ac.nz
Tel +64 3 378 6268
Research Interests
Dr Simran Maggo has a strong interest in drug-induced adverse drug reactions (ADRs) and is currently investigating the genetic basis of common and rare ADRs.
Publications
Kee, P. S., Karunanathie, H., Maggo, S. D. S., Kennedy, M. A., & Chua, E. W. (2023). Long-range polymerase chain reaction. In L. Domingues (Ed.), PCR: Methods and protocols: Methods in molecular biology (Vol. 2967). (2nd ed.) (pp. 181-192). New York, NY: Humana. doi: 10.1007/978-1-0716-3358-8_15
Chapter in Book - Research
Kee, P. S., Maggo, S. D. S., Kennedy, M. A., & Chin, P. K. L. (2023). The pharmacogenetics of CYP2D6 and CYP2C19 in a case series of antidepressant responses [Brief research report]. Frontiers in Pharmacology, 14, 1080117. doi: 10.3389/fphar.2023.1080117
Journal - Research Article
Kee, P. S., Maggo, S. D. S., Kennedy, M. A., Barclay, M. L., Miller, A. L., Lehnert, K., … Chin, P. K. L. (2022). Omeprazole treatment failure in gastroesophageal reflux disease and genetic variation at the CYP2C locus [Brief research report]. Frontiers in Genetics, 13, 869160. doi: 10.3389/fgene.2022.869160
Journal - Research Other
Hitchman, L. M., Faatoese, A., Merriman, T. R., Miller, A. L., Liau, Y., Graham, O. E. E., Kee, P. S., Pearson, J. F., … Cameron, V. A., Kennedy, M. A., & Maggo, S. D. S. (2022). Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples. Frontiers in Genetics, 13, 1016416. doi: 10.3389/fgene.2022.1016416
Journal - Research Article
Hitchman, L. M., Faatoese, A., Merriman, T. R., Miller, A. L., Liau, Y., Graham, O. E. E., Kee, P. S., Pearson, J. F., … Cameron, V. A., Kennedy, M. A., & Maggo, S. D. S. (2022, August-September). Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Poster Presentation (not in published proceedings)
Kee, P. S., Karunanathie, H., Maggo, S. D. S., Kennedy, M. A., & Chua, E. W. (2023). Long-range polymerase chain reaction. In L. Domingues (Ed.), PCR: Methods and protocols: Methods in molecular biology (Vol. 2967). (2nd ed.) (pp. 181-192). New York, NY: Humana. doi: 10.1007/978-1-0716-3358-8_15
Chapter in Book - Research
Chua, E. W., Maggo, S., & Kennedy, M. A. (2017). Long fragment polymerase chain reaction. In L. Domingues (Ed.), PCR: Methods in molecular biology (Vol. 1620). (pp. 65-74). New York, NY: Springer. doi: 10.1007/978-1-4939-7060-5_3
Chapter in Book - Research
Maggo, S. D. S., & Ashton, J. C. (2015). Statins and the brain: Good, bad or both? In E. R. Travers (Ed.), Statins: Medical uses, mechanisms of action and clinical outcomes. (pp. 81-104). Nova Science.
Chapter in Book - Research
Kee, P. S., Maggo, S. D. S., Kennedy, M. A., & Chin, P. K. L. (2023). The pharmacogenetics of CYP2D6 and CYP2C19 in a case series of antidepressant responses [Brief research report]. Frontiers in Pharmacology, 14, 1080117. doi: 10.3389/fphar.2023.1080117
Journal - Research Article
Hitchman, L. M., Faatoese, A., Merriman, T. R., Miller, A. L., Liau, Y., Graham, O. E. E., Kee, P. S., Pearson, J. F., … Cameron, V. A., Kennedy, M. A., & Maggo, S. D. S. (2022). Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples. Frontiers in Genetics, 13, 1016416. doi: 10.3389/fgene.2022.1016416
Journal - Research Article
Searchfield, G. D., Poppe, T. N. E. R., Durai, M., Jensen, M., Kennedy, M. A., Maggo, S., Miller, A. L., … Russell, B. R., … Wise, K. (2020). A proof-of-principle study of the short-term effects of 3,4-methylenedioxymethamphetamine (MDMA) on tinnitus and neural connectivity. International Journal of Neuroscience, 130(7), 671-682. doi: 10.1080/00207454.2019.1702544
Journal - Research Article
Liau, Y., Cree, S. L., Maggo, S., Miller, A. L., Pearson, J. F., Gladding, P. A., & Kennedy, M. A. (2019). A multiplex pharmacogenetics assay using the MinION nanopore sequencing device. Pharmacogenetics & Genomics, 29(9), 207-215. doi: 10.1097/fpc.0000000000000385
Journal - Research Article
Liau, Y., Maggo, S., Miller, A. L., Pearson, J. F., Kennedy, M. A., & Cree, S. L. (2019). Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications. Pharmacogenomics, 20(14), 1033-1047. doi: 10.2217/pgs-2019-0080
Journal - Research Article
Maggo, S. D. S., Sycamore, K. L. V., Miller, A. L., & Kennedy, M. A. (2019). The three ps: Psychiatry, pharmacy, and pharmacogenomics, a brief report from New Zealand. Frontiers in Psychiatry, 10, 690. doi: 10.3389/fpsyt.2019.00690
Journal - Research Article
Adehin, A., Bolaji, O. O., Maggo, S., & Kennedy, M. A. (2018). Genetic polymorphism of CYP2C9 and VKORC1 in the Nigerian population: Significance for warfarin therapy in the population. Polish Annals of Medicine, 25(2), 180-183. doi: 10.29089/2017.17.00041
Journal - Research Article
Maggo, S., & Ashton, J. C. (2018). Effect of cannabinoid receptor agonists on isolated rat atria. Journal of Cardiovascular Pharmacology, 72(4), 191-194. doi: 10.1097/fjc.0000000000000613
Journal - Research Article
Adehin, A., Bolaji, O. O., Maggo, S., & Kennedy, M. A. (2017). Relationship between metabolic phenotypes and genotypes of CYP1A2 and CYP2A6 in the Nigerian population. Drug Metabolism & Personalized Therapy, 32(1), 39-47. doi: 10.1515/dmpt-2016-0041
Journal - Research Article
Maggo, S. D. S., Chua, E. W., Chin, P., Cree, S., Pearson, J., Doogue, M., & Kennedy, M. A. (2017). A New Zealand platform to enable genetic investigation of adverse drug reactions. New Zealand Medical Journal, 130(1466), 62-69. Retrieved from http://www.nzma.org.nz/journal
Journal - Research Article
Maggo, S. D. S., Savage, R. L., & Kennedy, M. A. (2016). Impact of new genomic technologies on understanding adverse drug reactions. Clinical Pharmacokinetics, 55(4), 419-436. doi: 10.1007/s40262-015-0324-9
Journal - Research Article
Maggo, S., & Ashton, J. C. (2014). Effects of HMG-CoA reductase inhibitors on learning and memory in the guinea pig. European Journal of Pharmacology, 723, 294-304. doi: 10.1016/j.ejphar.2013.11.018
Journal - Research Article
Harrison-Woolrych, M., Härmark, L., Tan, M., Maggo, S., & van Grootheest, K. (2012). Epistaxis and other haemorrhagic events associated with the smoking cessation medicine varenicline: A case series from two national pharmacovigilance centres. European Journal of Clinical Pharmacology, 68, 1065-1072. doi: 10.1007/s00228-012-1220-y
Journal - Research Article
Harrison-Woolrych, M., Maggo, S., Tan, M., Savage, R., & Ashton, J. (2012). Cardiovascular events in patients taking varenicline: A case series from intensive postmarketing surveillance in New Zealand. Drug Safety, 35(1), 33-43. doi: 10.2165/11597690-000000000-00000
Journal - Research Article
Maggo, S., Clark, D., & Ashton, J. C. (2012). The effect of statins on performance in the Morris water maze in guinea pig. European Journal of Pharmacology, 674(2-3), 287-293. doi: 10.1016/j.ejphar.2011.11.006
Journal - Research Article
Rivers, J. R., Maggo, S. D. S., & Ashton, J. C. (2012). Neuroprotective effect of hydroxypropyl-β-cyclodextrin in hypoxia-ischemia. NeuroReport, 23(3), 134-138. doi: 10.1097/WNR.0b013e32834ee47c
Journal - Research Article
Maggo, S. D. S., Kennedy, M. A., & Clark, D. W. J. (2011). Clinical implications of pharmacogenetic variation on the effects of statins. Drug Safety, 34(1), 1-19. doi: 10.2165/11584380-000000000-00000
Journal - Research Article
Kee, P. S., Maggo, S. D. S., Kennedy, M. A., Barclay, M. L., Miller, A. L., Lehnert, K., … Chin, P. K. L. (2022). Omeprazole treatment failure in gastroesophageal reflux disease and genetic variation at the CYP2C locus [Brief research report]. Frontiers in Genetics, 13, 869160. doi: 10.3389/fgene.2022.869160
Journal - Research Other
Kee, P. S., Chin, P. K. L., Kennedy, M. A., & Maggo, S. D. S. (2020). Pharmacogenetics of statin-induced myotoxicity. Frontiers in Genetics, 11, 575678. doi: 10.3389/fgene.2020.575678
Journal - Research Other
Liau, Y., Chua, I., Kennedy, M. A., & Maggo, S. (2019). Pharmacogenetics of angiotensin-converting enzyme inhibitor-induced angioedema. Clinical & Experimental Allergy, 49, 142-154. doi: 10.1111/cea.13326
Journal - Research Other
Maggo, S., Kennedy, M. A., Barczyk, Z. A., Miller, A. L., Rucklidge, J. J., Mulder, R. T., & Foulds, J. A. (2019). Common CYP2D6, CYP2C9, and CYP2C19 gene variants, health anxiety, and neuroticism are not associated with self-reported antidepressant side effects [Brief report]. Frontiers in Genetics, 10, 1199. doi: 10.3389/fgene.2019.01199
Journal - Research Other
Foulds, J. A., Maggo, S. D. S., & Kennedy, M. A. (2016). Personalised prescribing in psychiatry: Has pharmacogenomics delivered on its promise? Australian & New Zealand Journal of Psychiatry, 50(6), 509-510. doi: 10.1177/0004867416640099
Journal - Research Other