2026
Journal - Research Article
Prendergast, P. J., Aitchison, A., Ho, S. S. C., Morris, V. K., Göbl, C., Dobson, R. C. J., Day, A. S., & Ogilvie, O. J. (2026). Integrated multiomics reveals stable microbe-metabolite relationships in pediatric celiac disease. Frontiers in Microbiology, 17, 1866060. doi: 10.3389/fmicb.2026.1866060
Smith, B. R., Magon, N. J., Sethi, A., Gray, S. G., Heath, S. G., Morris, V. K., & Göbl, C. (2026). The impact of physiological oxidants on triggering amyloid formation of the cell cycle regulator protein p16INK4A. Protein Science, 35, e70723. doi: 10.1002/pro.70723
Conference Contribution - Published proceedings: Abstract
Morris, V., Ganderton, J., Coldicott, R., Smith, B., Myall, D., Mayes, W., Yuan, Q., Morini, L., Sahota, J., … Pitcher, T., … Horne, K.-L., Williams, J., Göbl, C., Anderson, T., & Dalrymple-Alford, J. (2026). It'll all end in tears: Investigating novel biomarkers for Parkinson's disease from reflex tears. In A. Banstola (Ed.), Proceedings of the 42nd International Australasian Winter Conference on Brain Research (AWCBR). 42, 1.1, (pp. 39). Retrieved from https://www.awcbr.org
2025
Journal - Research Article
Reddington, C. J., Walsh, A. R., Kleffmann, T., Göbl, C., & Mace, P. D. (2025). Unconventional structure and function of PHD domains from additional sex combs-like proteins. FEBS Journal. Advance online publication. doi: 10.1111/febs.70206
Sethi, A., de Cordovez, P., Mohanty, B., Morris, V. K., & Göbl, C. (2025). 1H, 13C, 15N backbone chemical shift assignment of P18ink4c from Danio rerio (zebrafish) using solution-state NMR spectroscopy. Biomolecular NMR Assignments, 19, 275-279. doi: 10.1007/s12104-025-10245-2
Other Research Output
Goebl, C. (2025, October). Clinical implications of protein aggregation in cancer. UOC Biomedical Research Seminar Series, University of Otago, Christchurch, New Zealand. [Research Presentation].
2024
Journal - Research Article
Saseendran Nair, S., Kleffmann, T., Smith, B., Morris, V., Göbl, C., Pletzer, D., & Fellner, M. (2024). Comparative lipidomics profiles of planktonic and biofilms of methicillin-resistant and -susceptible Staphylococcus aureus. Analytical Biochemistry, 698, 115746. doi: 10.1016/j.ab.2024.115746
Heath, S. G., Naughton, J. D., Magon, N. J., Gray, S. G., Smith, B. R., Morris, V. K., & Göbl, C. (2024). Characterizing the amyloid core region of the tumor suppressor protein p16INK4a using a limited proteolysis and peptide-based approach. Journal of Biological Chemistry, 300(8), 107590. doi: 10.1016/j.jbc.2024.107590
Heath, S. G., Gray, S. G., Hamzah, E., O'Connor, K. M., Bozonet, S. M., Botha, A. D., de Cordovez, P., Magon, N. J., Naughton, J. D., … Göbl, C. (2024). Amyloid formation and depolymerization of tumor suppressor p16INK4a are regulated by a thiol-dependent redox mechanism. Nature Communications, 15(1), 5535. doi: 10.1038/s41467-024-49581-7
Conference Contribution - Poster Presentation (not in published proceedings)
O'Connor, K. M., Botha, A. D., Heath, S. G., Morris, V. K., & Göbl, C. (2024, September). Functional amyloid formation of tumour suppressor p16 protein during S-phase of the cell cycle. Poster session presented at the 34th Queenstown Molecular Biology Meeting (QMB), Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Heath, S. G., Gray, S. G., Hamzah, E. M., O'Connor, K. M., Bozonet, S. M., Botha, A. D., de Cordovez, P., Sethi, A., … Goebl, C. (2024, November). Amyloid formation and depolymerization of tumour suppressor p16INK4a are regulated by a thiol-dependent redox mechanism. Verbal presentation at the 32nd Meeting of The Society for Redox Research Australasia (SFRRA) and 11th Joint Meeting with The Society for Free Radical Research Japan (SFRRJ), Canberra, Australia.
Goebl, C., & Morris, V. K. (2024, September). High-throughput compound screening at the Biomolecular Interaction Centre. Verbal presentation at the Queenstown Research Week (QRW) Biomolecular Interactions Meeting, Queenstown, New Zealand.
Gray, S. G., Heath, S. G., Hamzah, E. M., Botha, A. D., O'Connor, K. M., Bozonet, S. M., … Göbl, C. (2024, September). Cancer-associated mutations of tumour suppressor p16INK4a increase the propensity for amyloid fibril formation. Verbal presentation at the Queenstown Research Week (QRW) Biomolecular Interactions Meeting, Queenstown, New Zealand.
Heath, S. G., Gray, S. G., Hamzah, E., O'Connor, K. M., Bozonet, S. M., Botha, A. D., de Cordovez, P., Magon, N. J., Schwartfeger, A. J., … Göbl, C., & Morris, V. K. (2024, September). Redox-controlled amyloid formation and disassembly of the tumour suppressor protein p16. Verbal presentation at the 34th Queenstown Molecular Biology Meeting (QMB), Queenstown, New Zealand.
2023
Journal - Research Article
Pulido, S., Rückert, H., Falsone, S. F., Göbl, C., Meyer, N. H., & Zangger, K. (2023). The membrane-binding bacterial toxin long direct repeat D inhibits protein translation. Biophysical Chemistry, 298, 107040. doi: 10.1016/j.bpc.2023.107040
Bozonet, S. M., Magon, N. J., Schwartfeger, A. J., Konigstorfer, A., Heath, S. G., Vissers, M. C. M., … Göbl, C., … Hampton, M. B. (2023). Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis. Journal of Biological Chemistry, 299(6), 104792. doi: 10.1016/j.jbc.2023.104792
Nechanitzky, R., Nechanitzky, D., Ramachandran, P., Duncan, G. S., Zheng, C., Göbl, C., … Mak, T. W. (2023). Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell Death & Differentiation, 30, 407-416. doi: 10.1038/s41418-022-01092-y
Conference Contribution - Published proceedings: Abstract
Faville, S., Hampton, M. B., Pace, P., Goebl, C., & Helem, S. (2023). Chemoproteomic analyses of the anti-cancer effects of portimines. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Austad, S., Pace, P., Goebl, C., & Hampton, M. (2023). Unravelling the functional role of peroxiredoxin oligomeric conformations. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Sethi, A., Darroch, H., Horsfield, J., Morris, V., & Göbl, C. (2023). Unravelling the functional impact of the p16INK4a transition into amyloid fibrils using zebrafish recombinant protein. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Du Toit, S., De Cordovez, P., Dickerhof, N., & Göbl, C. (2023). Characterising the substrate binding protein of a glutathione transporter from Streptococcus pneumoniae. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Schwartfeger, A., Bozonet, S. M., Magon, N. J., Göbl, C., Morris, V. K., & Hampton, M. B. (2023). Oxidation triggered amyloid assembly of the cell death regulator caspase-8. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Reddington, C., Walsh, A., Kleffmann, T., Goebl, C., Hinde, E., Day, C., & Mace, P. (2023). Redefining the ASXL PHD domain as a DNA damage recognition factor. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Morris, V., Kumar, S., Schwartfeger, A., Cristóvão, J., Göbl, C., & Gomes, C. (2023). Unravelling molecular details of protein interactions in Alzheimer's disease. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 68). Retrieved from https://www.awcbr.org
Kumar, S., Morris, V., & Goebl, C. (2023). Study of molecular interactions of TREM2 in Alzheimer's disease. In K.-L. Horne (Ed.), Proceedings of the 39th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 65). Retrieved from https://www.awcbr.org
Conference Contribution - Verbal presentation and other Conference outputs
Goebl, C., Heath, S., O'Connor, K. M., Bozonet, S., Botha, A., Smith, B., Hamzah, E., … Sethi, A., & Morris, V. K. (2023, August). A novel amyloid formation mechanism: Oxidation-induced transition of the tumour suppressor protein p16 into amyloid fibrils. Verbal presentation at the 33rd Queenstown Molecular Biology Meeting (QMB), Queenstown, New Zealand.
2022
Conference Contribution - Verbal presentation and other Conference outputs
Morris, V. K., Heath, S. G., O'Connor, K. M., Bozonnet, S., Gray, S. G., Naughton, J. D., Magon, N. J., Smith, B. R., Botha, A. D., … Göbl, C. (2022, August). The tumour suppressor protein p16 forms amyloid structures. Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
2021
Journal - Research Article
Gubensäk, N., Schrank, E., Hartlmüller, C., Göbl, C., Falsone, F. S., Becker, W., … Zangger, K. (2021). Structural and DNA binding properties of the cytoplasmic domain of Vibrio cholerae transcription factor ToxR. Journal of Biological Chemistry, 297(4), 101167. doi: 10.1016/j.jbc.2021.101167
Crowther, J. M., Gilmour, L. H., Porebski, B. T., Heath, S. G., Pattinson, N. R., Owen, M. C., … Göbl, C., & Dobson, R. C. J. (2021). Molecular basis of a redox switch: Molecular dynamics simulations and surface plasmon resonance provide insight into reduced and oxidised angiotensinogen. Biochemical Journal, 478, 3319-3330. doi: 10.1042/bcj20210476
Peskin, A. V., Meotti, F. C., Kean, K. M., Göbl, C., Peixoto, A. S., Pace, P. E., … Winterbourn, C. C. (2021). Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2. Journal of Biological Chemistry, 296, 100494. doi: 10.1016/j.jbc.2021.100494
Harjes, E., Jameson, G. B., Tu, Y.-H., Burr, N., Loo, T., Goroncy, A. K., … Göbl, C., … Norris, G. E. (2021). Experimentally based structural model of Yih1 provides insight into its function in controlling the key translational regulator Gcn2. FEBS Letters, 595, 324-340. doi: 10.1002/1873-3468.13990
Conference Contribution - Published proceedings: Abstract
Goldsmith, D., Göbl, C., & Morris, V. (2021). Insights into the molecular mechanism of TREM2: A major factor for Alzheimer's disease. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 108). Retrieved from https://www.faobmb2021.org
Heath, S. G., Magon, N. J., Winterbourn, C. C., Hampton, M., Morris, V. K., & Göbl, C. (2021). Oxidation induced amyloid formation of the tumour suppressor protein p16. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 33). Retrieved from https://www.faobmb2021.org
Morris, V., & Göbl, C. (2021). How oxidation induces rapid amyloid formation of the tumour suppressor protein p16. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 140). Retrieved from https://www.faobmb2021.org
Other Research Output
Goebl, C. (2021, August). The Southern BioNMR Centre: Establishing a new resource for measuring metabolites. UOC Research Seminar Series, University of Otago, Christchurch, New Zealand. [Research Presentation].
2020
Journal - Research Article
Göbl, C., Morris, V. K., van Dam, L., Visscher, M., Polderman, P. E., Hartlmüller, C., … Dansen, T. B. (2020). Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16INK4A. Redox Biology, 28, 101316. doi: 10.1016/j.redox.2019.101316
Other Research Output
Goebl, C. (2020, April). Protein amyloids and cancer. UOC Research Seminar Series, University of Otago, Christchurch, New Zealand. [Research Presentation].
2019
Journal - Research Article
Hartlmüller, C., Spreitzer, E., Göbl, C., Falsone, F., & Madl, T. (2019). NMR characterization of solvent accessibility and transient structure in intrinsically disordered proteins. Journal of Biomolecular NMR, 73(6-7), 305-317. doi: 10.1007/s10858-019-00248-2
Kubli, S. P., Bassin, C., Roux, C., Wakeham, A., Göbl, C., Zhou, W., … Gorrini, C. (2019). AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. PNAS, 116(9), 3604-3613. doi: 10.1073/pnas.1815126116
2018
Journal - Research Article
Cristóvão, J. S., Morris, V. K., Cardoso, I., Leal, S. S., Martínez, J. M., Botelho, H. M., Göbl, C., … Gomes, C. M. (2018). The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation. Science Advances, 4(6), eaaq1702. doi: 10.1126/sciadv.aaq1702
Göbl, C., & Madl, T. (2018). Entspannte Moleküle: NMR-Ober- flächen daten zur Strukturbestimmung. Biospektrum, 24(2), 161-163. doi: 10.1007/s12268-018-0898-5
Weber, B., Hora, M., Kazman, P., Göbl, C., Camilloni, C., Reif, B., & Buchner, J. (2018). The antibody light-chain linker regulates domain orientation and amyloidogenicity. Journal of Molecular Biology, 430(24), 4925-4940. doi: 10.1016/j.jmb.2018.10.024
2017
Journal - Research Article
Gourinchas, G., Etzl, S., Göbl, C., Vide, U., Madl, T., & Winkler, A. (2017). Long-range allosteric signaling in red light–regulated diguanylyl cyclases. Science Advances, 3(3), e1602498. doi: 10.1126/sciadv.1602498
Rodriquez Camargo, D. C., Tripsianes, K., Buday, K., Franko, A., Göbl, C., Hartlmüller, C., … Reif, B. (2017). The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes. Scientific Reports, 7, 44041. doi: 10.1038/srep44041
Journal - Research Other
Göbl, C., Focke-Teikl, M., Najafi, N., Schrank, E., Madl, T., Kosol, S., … Tjandra, N. (2017). Flexible IgE epitope-containing domains of Phl p 5 cause high allergenic activity. Journal of Allergy & Clinical Immunology, 140(4), 1187-1191. doi: 10.1016/j.jaci.2017.05.005
Conference Contribution - Published proceedings: Abstract
Cristóvão, J. S., Morris, V., Cardoso, I., Leal, S. S., Botelho, H. M., Göbl, C., … Gomes, C. M. (2017). The neuronal S100B cytokine targeting amyloid-β aggregation in Alzheimer's disease. FEBS Journal, 284(Suppl. 1), (pp. 184). doi: 10.1111/febs.14174
2016
Journal - Research Article
Göbl, C., Resch, M., Strickland, M., Hartlmüller, C., Viertler, M., Tjandra, N., & Madl, T. (2016). Increasing the chemical-shift dispersion of unstructured proteins with a covalent lanthanide shift reagent [Communication]. Angewandte Chemie International Edition, 55(47), 14847-14851. doi: 10.1002/anie.201607261
Strickland, M., Schwieters, C. D., Göbl, C., Opina, A. C. L., Strub, M.-P., Swenson, R. E., … Tjandra, N. (2016). Characterizing the magnetic susceptibility tensor of lanthanide-containing polymethylated-DOTA complexes. Journal of Biomolecular NMR, 66(2), 125-139. doi: 10.1007/s10858-016-0061-x
Suárez-Calvet, M., Neumann, M., Arzberger, T., Abou-Ajram, C., Funk, E., Hartmann, H., … Göbl, C., … Haass, C. (2016). Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS. Acta Neuropathologica, 131(4), 587-604. doi: 10.1007/s00401-016-1544-2
Journal - Research Other
Hartlmüller, C., Göbl, C., & Madl, T. (2016). Prediction of protein structure using surface accessibility data [Communication]. Angewandte Chemie International Edition, 55(39), 11970-11974. doi: 10.1002/anie.201604788
2015
Journal - Research Article
Chromikova, V., Mader, A., Hofbauer, S., Göbl, C., Madl, T., Gach, J. S., … Kunert, R. (2015). Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM. Biochimica et Biophysica Acta: Proteins & Proteomics, 1854(10, Pt A), 1536-1544. doi: 10.1016/j.bbapap.2015.02.018
Gersch, M., Famulla, K., Dahmen, M., Göbl, C., Malik, I., Richter, K., … Sieber, S. A. (2015). AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control. Nature Communications, 6, 6320. doi: 10.1038/ncomms7320
Hacker, C., Christ, N. A., Duchardt-Ferner, E., Korn, S., Göbl, C., Berninger, L., … Wöhnert, J. (2015). The solution structure of the lantibiotic immunity protein NisI and its interactions with nisin. Journal of Biological Chemistry, 290(48), 28869-28886. doi: 10.1074/jbc.M115.679969
Journal - Professional & Other Non-Research Articles
Göbl, C., Wolf, M., Pröll, T., Woss, D., & Schumergruber, A. (2015). Waste heat utilization in refrigerating plants with the aid of high-temperature heat pumps. BWK, 67(10), 44-48. [Review].
2014
Journal - Research Article
Göbl, C., Madl, T., Simon, B., & Sattler, M. (2014). NMR approaches for structural analysis of multidomain proteins and complexes in solution. Progress in Nuclear Medicine Resonance Spectroscopy, 80, 26-63. doi: 10.1016/j.pnmrs.2014.05.003
Conference Contribution - Published proceedings: Abstract
Pulido, S. A., Rückert, H. M., Göbl, C., Falsone, F., Meyer, H., & Zangger, K. (2014). Functional and structural studies of the bacterial toxin ldrD. FEBS Journal, 281(Suppl. 1), (pp. 284). doi: 10.1111/febs.12919
2012
Journal - Research Article
Kosol, S., Schrank, E., Bukvić Krajačić, M., Wagner, G. E., Meyer, N. H., Göbl, C., … Novak, P. (2012). Probing the interactions of macrolide antibiotics with membrane-mimetics by NMR spectroscopy. Journal of Medicinal Chemistry, 55(11), 5632-5636. doi: 10.1021/jm300647f
Journal - Research Other
Göbl, C., & Tjandra, N. (2012). Application of solution NMR spectroscopy to study protein dynamics. Entropy, 14(3), 581-598. doi: 10.3390/e14030581
Awarded Doctoral Degree
Göbl, C. (2012). Paramagnetic relaxation enhancements in structure determination of proteins by NMR spectroscopy (PhD). Universität Graz, Graz, Austria. 97p. Retrieved from http://inis.iaea.org/search/search.aspx?orig_q=RN:44111672
2011
Conference Contribution - Published proceedings: Abstract
Schrank, E., Kosol, S., Čuljak, K., Göbl, C., Zangger, K., & Novak, P. (2011). Deciphering interactions of macrolide antibiotics with membrane- mimetics by NMR spectroscopy. Proceedings of the Second World Conference on Physico-Chemical Methods in Drug Discovery and Development. Retrieved from https://www.bib.irb.hr/527071?rad=527071
Kosol, S., Göbl, C., Čuljak, K., Hohlweg, W., Novak, P., & Zangger, K. (2011). Determining the orientation of drugs in receptors by solvent paramagnetic relaxation NMR spectroscopy. Proceedings of the Second World Conference on Physico-Chemical Methods in Drug Discovery and Development. Retrieved from https://www.bib.irb.hr/527060?rad=527060
2010
Journal - Research Article
Göbl, C., Dulle, M., Hohlweg, W., Grossauer, J., Falsone, S. F., Glatter, O., & Zangger, K. (2010). Influence of phosphocholine alkyl Chain length on peptide—micelle interactions and micellar size and shape. Journal of Physical Chemistry B, 114(13), 4717-4724. doi: 10.1021/jp9114089
Göbl, C., Kosol, S., Stockner, T., Rückert, H. M., & Zangger, K. (2010). Solution structure and membrane binding of the toxin Fst of the par addiction module. Biochemistry, 49(31), 6567-6575. doi: 10.1021/bi1005128
Pieber, B., Schober, S., Goebl, C., & Mittelbach, M. (2010). Novel sensitive determination of steryl glycosides in biodiesel by gas chromatography–mass spectroscopy. Journal of Chromatography A, 1217(42), 6555-6561. doi: 10.1016/j.chroma.2010.08.006
2009
Journal - Research Article
Zangger, K., Respondek, M., Göbl, C., Hohlweg, W., Rasmussen, K., Grampp, G., & Madl, T. (2009). Positioning of micelle-bound peptides by paramagnetic relaxation enhancements. Journal of Physical Chemistry B, 113(13), 4400-4406. doi: 10.1021/jp808501x
2007
Journal - Research Article
Respondek, M., Madl, T., Göbl, C., Golser, R., & Zangger, K. (2007). Mapping the orientation of helices in micelle-bound peptides by paramagnetic relaxation waves. Journal of the American Chemical Society, 129(16), 5228-5234. doi: 10.1021/ja069004f
