Co-leader of The Infection Group
Co-director of One Health Aotearoa
Vice-Chancellor Designate
MB ChB, MD (Otago), MSc (Lond), DTM&H (Liv), FRACP, FRCPA, FFSc(RCPA)
Email david.murdoch@otago.ac.nz
Tel +64 3 479 8253
Current roles
Professor David Murdoch is the co-leader of The Infection Group, the co-director of One Health Aotearoa, a Senior Associate in the Department of International Health at Johns Hopkins School of Public Health, and a clinical microbiologist at Canterbury Health Laboratories.
In February 2022, Professor Murdoch will begin in the role of Vice-Chancellor of the University of Otago.
Research interests
David’s main research interests are the epidemiology, diagnosis and prevention of respiratory tract infections, pneumococcal disease, legionellosis, bloodstream infections, and the role of vitamin D in infectious diseases.
He has a particular interest in the microbial aetiology of pneumonia, and is the Laboratory Director of the Pneumonia Etiology Research for Child Health (PERCH) project which is focused on determining the causes of severe pneumonia in young children from developing countries. David has ongoing projects based in nine countries in Africa and Asia.
Publications
Shrestha, S., Gurung, M., Amatya, P., Bijukchhe, S., Bose, A. S., Carter, M. J., … Murdoch, D. R., … & the PneumoNepal Study Group. (2022). Effect of the of 10-valent pneumococcal conjugate vaccine in Nepal 4 years after introduction: An observational cohort study. Lancet Global Health, 10, e1494-e1504. doi: 10.1016/S2214-109X(22)00281-9
Cheung, J., Nordmeier, K., Kelland, S., Harrington, M., Williman, J., Storer, M., Beaglehole, B., … Chambers, S., Epton, M., Freeman, J., Murdoch, D., Werno, A., & Maze, M. (2022). Symptom persistence and recovery among Covid-19 survivors during a limited outbreak in Canterbury, New Zealand: A prospective cohort study. Internal Medicine Journal. Advance online publication. doi: 10.1111/imj.15930
Téllez, A., Ambrosioni, J., Hernández-Meneses, M., Llopis, J., Ripa, M., Chambers, S. T., … Raymond, N., … the International Collaboration on Endocarditis (ICE) Investigators, including Murdoch, D. R. (2022). Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci. Journal of Infection, 85, 137-146. doi: 10.1016/j.jinf.2022.05.023
Park, D. E., Watson, N. L., Focht, C., Feikin, D., Hammitt, L., Brooks, W. A., … Murdoch, D. R., … McCollum, E. D. (2022). Digitally recorded and remotely classified lung auscultation compared with conventional stethoscope classifications among children aged 1-59 months enrolled in the Pneumonia Etiology Research for Child Health (PERCH) case-control study. BMJ Open Respiratory Research, 9, e001144. doi: 10.1136/bmjresp-2021-001144
Kandasamy, R., Lo, S., Gurung, M., Carter, M. J., Gladstone, R., Lees, J., … Murdoch, D. R., … Pollard, A. J. (2022). Effect of childhood vaccination and antibiotic use on pneumococcal populations and genome-wide associations with disease among children in Nepal: An observational study. Lancet Microbe. Advance online publication. doi: 10.1016/S2666-5247(22)00066-0
Pollard, A. J., & Murdoch, D. R. (2007). Bergmedizin: Höhenbedingte erkrankungen und gesundheitsgefahren bei bergsteigern (3rd ed.). Bern, Switzerland: Hans Huber, 240p.
Authored Book - Research
Pollard, A. J., & Murdoch, D. R. (2003). The high altitude medicine handbook (3rd ed.). Oxon, UK: Radcliffe Medical Press, 193p.
Authored Book - Other
Pollard, A. J., & Murdoch, D. R. (2001). Travel Medicine. Oxford: Health Press, 152p.
Authored Book - Other
Pollard, A. J., & Murdoch, D. R. (1998). The High Altitude Medicine Handbook (2 ed.). Abingdon: Radcliffe Medical Press, 165p.
Authored Book - Other
Begg, E., Barclay, M., Vella-Brincat, J., Gardiner, S. J., Doogue, M., McDermott, L., … Chambers, S., & Murdoch, D. (Eds.). (2004). Preferred Medicines List (8th ed.). Christchurch: The Caxton Press, 172p.
Edited Book - Other
Murdoch, D. R., Werno, A. M., & Jennings, L. C. (2019). Microbiological diagnosis of respiratory illness: Recent advances. In R. Wilmott, A. Bush, R. Deterding, F. Ratjen, P. Sly, H. Zar & H. Li (Eds.), Kendig's disorders of the respiratory tract in children. (9 ed.) (pp. 396-405.e3). Philadelphia, PA: Elsevier. doi: 10.1016/B978-0-323-44887-1.00022-5
Chapter in Book - Research
Murdoch, D. R. (2005). Streptococcus pneumoniae. In J. Fuchs & M. Podda (Eds.), Encyclopedia of diagnostic genomics and proteomics. (pp. 1236-1240). New York: Marcel Dekker.
Chapter in Book - Research
Murdoch, D. (2004). Altitude sickness. In Clinical Evidence 11. (pp. 1767-1773). BMJ Publishing Group. Retrieved from http://www.clinicalevidence.com/ceweb/conditions/index.jsp
Chapter in Book - Research
Pollard, A. J., Litch, J. A., & Murdoch, D. R. (1998). Children at altitude. In H. Ohno, T. Kobayashi, S. Masuyama & M. Nakashima (Eds.), Progress in mountain medicine and high mountain physiology. (pp. 422-424). Japanese Society of Mountain Medicine.
Chapter in Book - Research
Murdoch, D. (2013). Pathology. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 45-49). Christchurch, New Zealand: University of Otago.
Chapter in Book - Other
Bryce, A., Foley, L., Phillipson, J., Slow, S., Storer, M., Williman, J., Beasley, R., Bhally, H., … Dummer, J., Epton, M., … Gracie, K., Hancox, R. J., Hills, T., Hogg, S., … Kearns, N., … Murdoch, D., Raymond, N., … Maze, M. J. (2022). Clinical features of patients hospitalised with COVID-19 from February to October 2020, during the early waves of the pandemic in New Zealand. New Zealand Medical Journal, 135(1552), 120-130. Retrieved from https://journal.nzma.org.nz/
Journal - Research Article
Carter, M. J., Gurung, M., Pokhrel, B., Bijukchhe, S. M., Karmacharya, S., Khadka, B., … Murdoch, D. R., … Pollard, A. J. (2022). Childhood invasive bacterial disease in Kathmandu Nepal (2005-2013). Pediatric Infectious Disease Journal, 41(3), 192-198. doi: 10.1097/inf.0000000000003421
Journal - Research Article
Cheung, J., Nordmeier, K., Kelland, S., Harrington, M., Williman, J., Storer, M., Beaglehole, B., … Chambers, S., Epton, M., Freeman, J., Murdoch, D., Werno, A., & Maze, M. (2022). Symptom persistence and recovery among Covid-19 survivors during a limited outbreak in Canterbury, New Zealand: A prospective cohort study. Internal Medicine Journal. Advance online publication. doi: 10.1111/imj.15930
Journal - Research Article
Kandasamy, R., Lo, S., Gurung, M., Carter, M. J., Gladstone, R., Lees, J., … Murdoch, D. R., … Pollard, A. J. (2022). Effect of childhood vaccination and antibiotic use on pneumococcal populations and genome-wide associations with disease among children in Nepal: An observational study. Lancet Microbe. Advance online publication. doi: 10.1016/S2666-5247(22)00066-0
Journal - Research Article
Park, D. E., Watson, N. L., Focht, C., Feikin, D., Hammitt, L., Brooks, W. A., … Murdoch, D. R., … McCollum, E. D. (2022). Digitally recorded and remotely classified lung auscultation compared with conventional stethoscope classifications among children aged 1-59 months enrolled in the Pneumonia Etiology Research for Child Health (PERCH) case-control study. BMJ Open Respiratory Research, 9, e001144. doi: 10.1136/bmjresp-2021-001144
Journal - Research Article
Shrestha, S., Gurung, M., Amatya, P., Bijukchhe, S., Bose, A. S., Carter, M. J., … Murdoch, D. R., … & the PneumoNepal Study Group. (2022). Effect of the of 10-valent pneumococcal conjugate vaccine in Nepal 4 years after introduction: An observational cohort study. Lancet Global Health, 10, e1494-e1504. doi: 10.1016/S2214-109X(22)00281-9
Journal - Research Article
Slow, S., Anderson, T., Murdoch, D. R., Bloomfield, S., Winter, D., & Biggs, P. J. (2022). Extensive epigenetic modification with large-scale chromosomal and plasmid recombination characterise the Legionella longbeachae serogroup 1 genome. Scientific Reports, 12, 5810. doi: 10.1038/s41598-022-09721-9
Journal - Research Article
Téllez, A., Ambrosioni, J., Hernández-Meneses, M., Llopis, J., Ripa, M., Chambers, S. T., … Raymond, N., … the International Collaboration on Endocarditis (ICE) Investigators, including Murdoch, D. R. (2022). Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci. Journal of Infection, 85, 137-146. doi: 10.1016/j.jinf.2022.05.023
Journal - Research Article
Awori, J. O., Kamau, A., Morpeth, S., Kazungu, S., Silaba, M., Sande, J., … Murdoch, D. R., … Scott, J. A. G. (2021). The etiology of pneumonia in HIV-uninfected Children in Kilifi, Kenya: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S29-S39. doi: 10.1097/inf.0000000000002653
Journal - Research Article
Baillie, V. L., Moore, D. P., Muthunjwa, A., Baggett, H. C., Brooks, A., Feikin, D. R., … Murdoch, D. R., … Madhi, S. A. (2021). Epidemiology of the rhinovirus (RV) in African and Southeast Asian children: A case-control pneumonia etiology study. Viruses, 13(7), 1249. doi: 10.3390/v13071249
Journal - Research Article
Bothara, R. K., Tafuna'i, M., Wilkinson, T. J., Desrosiers, J., Jack, S., Pattemore, P. K., Walls, T., Sopoaga, F., Murdoch, D. R., & Miller, A. P. (2021). Global health classroom: Mixed methods evaluation of an interinstitutional model for reciprocal global health learning among Samoan and New Zealand medical students. Globalization & Health, 17, 99. doi: 10.1186/s12992-021-00755-8
Journal - Research Article
Brooks, W. A., Zaman, K., Goswami, D., Prosperi, C., Endtz, H. P., Hossain, L., … Murdoch, D. R., … Deloria Knoll, M. (2021). The etiology of childhood pneumonia in Bangladesh: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S79-S90. doi: 10.1097/inf.0000000000002648
Journal - Research Article
Brueggemann, A. B., Jansen van Rensburg, M. J., Shaw, D., Jolley, K. A., McCarthy, N. D., Maiden, M. C. J., … Murdoch, D. R., … Zhou, F. (2021). Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and territories in the Invasive Respiratory Infection Surveillance Initiative: A prospective analysis of surveillance data. Lancet Digital Health, 3(6), e360-e370. doi: 10.1016/S2589-7500(21)00077-7
Journal - Research Article
Bunthi, C., Rhodes, J., Thamthitiwat, S., Higdon, M. M., Chuananon, S., Amorninthapichet, T., … Murdoch, D. R., … Akarasewi, P. (2021). Etiology and clinical characteristics of severe pneumonia among young children in Thailand: Pneumonia Etiology Research for Child Health (PERCH) case-control study findings, 2012-2013. Pediatric Infectious Disease Journal, 40, S91-S100. doi: 10.1097/inf.0000000000002768
Journal - Research Article
Chambers, S. T., Withers, A., Dawson, K., Anderson, T., Williman, J., Murdoch, D., Scott-Thomas, A., & Slow, S. (2021). How safe are gloves and masks used for protection against Legionella longbeachae infection when gardening? Letters in Applied Microbiology, 73, 616-622. doi: 10.1111/lam.13546
Journal - Research Article
Deloria Knoll, M., Prosperi, C., Baggett, H. C., Brooks, W. A., Feikin, D. R., Hammitt, L. L., … Murdoch, D. R., … O'Brien, K. L. (2021). Introduction to the site-specific etiologic results from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S1-S6. doi: 10.1097/inf.0000000000002778
Journal - Research Article
Ebruke, B. E., Deloria Knoll, M., Haddix, M., Zaman, S. M. A., Prosperi, C., Feikin, D. R., … Murdoch, D. R., … Howie, S. R. C. (2021). The aetiology of pneumonia from analysis of lung aspirate and pleural fluid samples: Findings from the PERCH study. Clinical Infectious Diseases, 73, e3788-e3796. doi: 10.1093/cid/ciaa1032
Journal - Research Article
Geoghegan, J. L., Douglas, J., Ren, X., Storey, M., Hadfield, J., Silander, O. K., … Baker, M. G., Murdoch, D. R., … de Ligt, J. (2021). Use of genomics to track Coronavirus disease outbreaks, New Zealand. Emerging Infectious Diseases, 27(5), 1317-1322. doi: 10.3201/eid2705.204579
Journal - Research Article
Howie, S. R. C., Ebruke, B. E., McLellan, J. L., Deloria Knoll, M., Dione, M. M., Feikin, D. R., … Murdoch, D. R., … Zaman, S. M. A. (2021). The etiology of childhood Pneumonia in The Gambia: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S7-S17. doi: 10.1097/inf.0000000000002766
Journal - Research Article
Jolliffe, D. A., Camargo, Jr, C. A., Sluyter, J. D., Aglipay, M., Aloia, J. F., Ganmaa, D., … Murdoch, D. R., … Martineau, A. R. (2021). Vitamin D supplementation to prevent acute respiratory infections: A systematic review and meta-analysis of aggregate data from randomised controlled trials. Lancet Diabetes & Endocrinology, 9, 276-292. doi: 10.1016/S2213-8587(21)00051-6
Journal - Research Article
Mohammadi, A., Chambers, S. T., Slow, S., Anderson, T., Williman, J., Scott, P., Murdoch, D., & Scott-Thomas, A. (2021). Presence of Legionella Longbeachae in pine but not composted green waste used in manufacture of potting soils in New Zealand. Journal of Applied & Environmental Microbiology, 9(1), 1-4. doi: 10.12691/jaem-9-1-1
Journal - Research Article
Moore, D. P., Baillie, V. L., Mudau, A., Wadula, J., Adams, T., Mangera, S., … Murdoch, D. R., … Madhi, S. A. (2021). The etiology of pneumonia in HIV-uninfected South African children: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S59-S68. doi: 10.1097/inf.0000000000002650
Journal - Research Article
Moore, D. P., Baillie, V. L., Mudau, A., Wadula, J., Adams, T., Mangera, S., … Murdoch, D. R., … Madhi, S. A. (2021). The etiology of pneumonia in HIV-1-infected South African children in the era of antiretroviral treatment: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S69-S78. doi: 10.1097/inf.0000000000002651
Journal - Research Article
Mwananyanda, L., Thea, D. M., Chipeta, J., Kwenda, G., Mulindwa, J. M., Mwenechanya, M., … Murdoch, D. R., … Seidenberg, P. (2021). The etiology of pneumonia in Zambian children: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S40-S49. doi: 10.1097/inf.0000000000002652
Journal - Research Article
Nguyen, T., Adnan, M., Nguyen, B. P., de Ligt, J., Geoghegan, J. L., Dean, R., … Baker, M. G., … Murdoch, D. R., … Simpson, C. R. (2021). COVID-19 vaccine strategies for Aotearoa New Zealand: A mathematical modelling study. Lancet Regional Health: Western Pacific, 15, 100256. doi: 10.1016/j.lanwpc.2021.100256
Journal - Research Article
Park, D. E., Higdon, M. M., Prosperi, C., Baggett, H. C., Brooks, W. A., Feikin, D. R., … Murdoch, D. R., … Deloria Knoll, M. (2021). Upper respiratory tract co-detection of human endemic coronaviruses and high-density pneumococcus associated with increased severity among HIV-uninfected children under 5 years old in the PERCH study. Pediatric Infectious Disease Journal, 40(6), 503-512. doi: 10.1097/inf.0000000000003139
Journal - Research Article
Pericàs, J. M., Llopis, J., Athan, E., Hernández-Meneses, M., Hannan, M. M., Murdoch, D. R., … on behalf of the International Collaboration on Endocarditis (ICE) Investigators. (2021). Prospective cohort study of infective endocarditis in people who inject drugs. Journal of the American College of Cardiology, 77(5), 544-555. doi: 10.1016/j.jacc.2020.11.062
Journal - Research Article
Scott, P., Zhang, J., Anderson, T., Priest, P. C., Chambers, S., Smith, H., Murdoch, D. R., French, N., & Biggs, P. J. (2021). Whole-genome sequencing and ad hoc shared genome analysis of Staphylococcus aureus isolates from a New Zealand primary school. Scientific Reports, 11(1), 20328. doi: 10.1038/s41598-021-99080-8
Journal - Research Article
Seidenberg, P., Mwananyanda, L., Chipeta, J., Kwenda, G., Mulindwa, J. M., Mwansa, J., … Murdoch, D. R., … Thea, D. M. (2021). The etiology of pneumonia in HIV-infected Zambian children: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S50-S58. doi: 10.1097/inf.0000000000002649
Journal - Research Article
Shrestha, S., Stockdale, L. K., Gautam, M. C., Gurung, M., Feng, S., Maskey, P., … Murdoch, D. R., … Pollard, A. J. (2021). Impact of vaccination on Haemophilus influenzae type b carriage in healthy children less than 5 years of age in an urban population in Nepal. Journal of Infectious Diseases, 224(Suppl. 3), S267-S274. doi: 10.1093/infdis/jiab072
Journal - Research Article
Tapia, M. D., Sylla, M., Driscoll, A. J., Touré, A., Kourouma, N., Sissoko, S., … Murdoch, D. R., … Kotloff, K. L. (2021). The etiology of childhood pneumonia in Mali: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Study. Pediatric Infectious Disease Journal, 40, S18-S28. doi: 10.1097/inf.0000000000002767
Journal - Research Article
Carter, M. J., Gurung, P., Jones, C., Rajkarnikar, S., Kandasamy, R., Gurung, M., … Murdoch, D. R., … for the PneumoNepal Study Group. (2020). Assessment of an antibody-in-lymphocyte supernatant assay for the etiological diagnosis of pneumococcal pneumonia in children. Frontiers in Cellular & Infection Microbiology, 9, 459. doi: 10.3389/fcimb.2019.00459
Journal - Research Article
Gallagher, K. E., Deloria Knoll, M., Prosperi, C., Baggett, H. C., Brooks, W. A., Feiken, D. R., … Murdoch, D. R., … for The PERCH Study Group. (2020). The predictive performance of a pneumonia severity score in Human Immunodeficiency Virus-negative children presenting to hospital in seven low- and middle-income countries. Clinical Infectious Diseases, 70, 1050-1057. doi: 10.1093/cid/ciz350
Journal - Research Article
Geoghegan, J. L., Ren, X., Storey, M., Hadfield, J., Jelley, L., Jefferies, S., … Baker, M. G., Murdoch, D. R., … de Ligt, J. (2020). Genomic epidemiology reveals transmission patterns and dynamics of SARS-CoV-2 in Aotearoa New Zealand. Nature Communications, 11(1), 6351. doi: 10.1038/s41467-020-20235-8
Journal - Research Article
Hannaway, R. F., Wang, X., Schneider, M., Slow, S., Cowan, J., Brockway, B., Schofield, M. R., Morgan, X. C., Murdoch, D. R., & Ussher, J. E. (2020). Mucosal-associated invariant T cells and Vδ2+ γδ T cells in community acquired pneumonia: Association of abundance in sputum with clinical severity and outcome. Clinical & Experimental Immunology, 199(2), 201-215. doi: 10.1111/cei.13377
Journal - Research Article
McCollum, E. D., Park, D. E., Watson, N. L., Fancourt, N. S. S., Focht, C., Baggett, H. C., … Murdoch, D. R., … Hammitt, L. L. (2020). Digital auscultation in PERCH: Associations with chest radiography and pneumonia mortality in children. Pediatric Pulmonology, 55, 3197-3208. doi: 10.1002/ppul.25046
Journal - Research Article
Mohammadi, A., Chambers, S. T., Scott-Thomas, A., Lewis, J. G., Anderson, T., Podmore, R., Williman, J., Murdoch, D., & Slow, S. (2020). Enhancement of culture of Legionella longbeachae from respiratory samples using immunomagnetic separation and antimicrobial decontamination. Journal of Clinical Microbiology, 58(11), e01218-20. doi: 10.1128/jcm.01218-20
Journal - Research Article
Slow, S., Pearson, J. F., Florkowski, C. M., Elder, P. A., Lewis, J. G., Kennedy, M. A., & Murdoch, D. R. (2020). Effect of genetic factors on the response to vitamin D3 supplementation in the VIDARIS randomised controlled trial. Nutrition, 75-76, 110761. doi: 10.1016/j.nut.2020.110761
Journal - Research Article
Kandasamy, R., Gurung, M., Thorson, S., Yu, L.-M., Galal, U., Voysey, M., … Murdoch, D. R., … Pollard, A. J. (2019). Comparison of two schedules of two-dose priming with the ten-valent pneumococcal conjugate vaccine in Nepalese children: An open-label, randomised non-inferiority controlled trial. Lancet Infectious Diseases, 19, 156-164. doi: 10.1016/s1473-3099(18)30568-1
Journal - Research Article
Martineau, A. R., Jolliffe, D. A., Greenberg, L., Aloia, J. F., Bergman, P., Dubnoz-Raz, G., … Murdoch, D. R., … Hooper, R. L. (2019). Vitamin D supplementation to prevent acute respiratory infections: Individual participant data meta-analysis. Health Technology Assessment, 23(2). doi: 10.3310/hta23020
Journal - Research Article